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O'Hare Intl

$50+ Cheap flights from Missouri to O'Hare Intl (ORD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ORD
Nov 22 — Nov 291
Sat 11/22
Sat 11/29
1 adult, Economy
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Cheap flight deals from Missouri to O'Hare Intl

Keep the following information in mind while searching for Missouri to O'Hare Intl flight deals. Data was last updated October 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$104
(Mytrip)

One-way from

$50
(Southwest)

Popular in

April

Cheapest in

August

Average price

$273

Good round-trip deal

$129 or less

Good one-way deal

$211 or less
Provider with most accurate pricing for Lambert-St Louis-Chicago (CHI) flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Chicago (CHI) flights.
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From Missouri to Chicago O'Hare Intl
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One-way flight from Missouri to Chicago O'Hare Intl
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Highest demand for flights based on searches. 7% potential increase in price ($19 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Missouri to Chicago O'Hare Intl.
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Price to beat on a one-way flight from Missouri to Chicago O'Hare Intl.
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Find flight deals from Missouri to O'Hare Intl

Cheapest flights from Missouri to O'Hare Intl
Explore the most affordable flight options available from Missouri to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.

This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/67:36 pmSTL - ORD
Nonstop1h 39mAmerican Airlines
Sat 12/132:48 pmORD - STL
Nonstop1h 31mAmerican Airlines
Deal found 10/21$109
This Booking.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/189:50 amUIN - ORD
Nonstop1h 20mContour
Thu 11/207:30 pmORD - UIN
Nonstop1h 20mContour
Deal found 10/22$110
This Mytrip deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:30 amCGI - ORD
Nonstop1h 40mContour
Sat 12/2711:50 amORD - CGI
Nonstop1h 35mContour
Deal found 10/23$121
This Mytrip deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/53:05 pmCGI - ORD
Nonstop1h 40mContour
Sun 11/911:50 amORD - CGI
Nonstop1h 35mContour
Deal found 10/21$122
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/188:01 pmSTL - ORD
Nonstop1h 29mAmerican Airlines
Tue 1/68:52 amORD - STL
Nonstop1h 30mAmerican Airlines
Deal found 10/22$127
This Booking.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/59:30 amCGI - ORD
Nonstop1h 40mContour
Sun 12/711:50 amORD - CGI
Nonstop1h 35mContour
Deal found 10/22$132
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/510:42 amSTL - ORD
1 stop11h 42mFrontier
Fri 12/127:00 amORD - STL
1 stop27h 14mFrontier
Deal found 10/21$138
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/89:30 amCGI - ORD
Nonstop1h 40mContour
Fri 12/1211:50 amORD - CGI
Nonstop1h 35mContour
Deal found 10/23$139
This Mytrip deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/59:50 amUIN - ORD
Nonstop1h 20mContour
Sun 11/92:00 pmORD - UIN
Nonstop1h 20mContour
Deal found 10/21$143
This Mytrip deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:50 amUIN - ORD
Nonstop1h 20mContour
Mon 11/107:30 pmORD - UIN
Nonstop1h 20mContour
Deal found 10/22$145
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:42 pmSTL - ORD
Nonstop1h 30mUnited Airlines
Sun 12/149:30 amORD - STL
Nonstop1h 31mUnited Airlines
Deal found 10/22$145
This Mytrip deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/34:05 pmCGI - ORD
Nonstop1h 40mContour
Fri 11/74:30 pmORD - CGI
Nonstop1h 35mContour
Deal found 10/22$147

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to O'Hare Intl that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Missouri to Chicago O'Hare Intl Airport that are best for you.

Fly from

Missouri

Fly to

O'Hare Intl

Route

Depart

Return

Price

QuincyChicago

UIN - ORD

UINORD

Quincy Regional

Tue 3/10

9:50 am-11:10 am

Nonstop1h 20m

Chicago O'Hare Intl

Wed 3/11

7:30 pm-8:50 pm

Nonstop1h 20m

$118

Cape GirardeauChicago

CGI - ORD

CGIORD

Cape Girardeau

Thu 12/25

9:30 am-11:10 am

Nonstop1h 40m

Chicago O'Hare Intl

Sat 12/27

11:50 am-1:25 pm

Nonstop1h 35m

$121

Cape GirardeauChicago

CGI - ORD

CGIORD

Cape Girardeau

Fri 1/16

9:30 am-11:10 am

Nonstop1h 40m

Chicago O'Hare Intl

Sun 1/18

11:50 am-1:25 pm

Nonstop1h 35m

$122

Cape GirardeauChicago

CGI - ORD

CGIORD

Cape Girardeau

Wed 11/5

3:05 pm-4:45 pm

Nonstop1h 40m

Chicago O'Hare Intl

Sun 11/9

11:50 am-1:25 pm

Nonstop1h 35m

$122

Cape GirardeauChicago

CGI - ORD

CGIORD

Cape Girardeau

Tue 11/4

3:05 pm-4:45 pm

Nonstop1h 40m

Chicago O'Hare Intl

Sat 11/8

11:50 am-1:25 pm

Nonstop1h 35m

$122

Cape GirardeauChicago

CGI - ORD

CGIORD

Cape Girardeau

Fri 12/5

9:30 am-11:10 am

Nonstop1h 40m

Chicago O'Hare Intl

Sun 12/7

11:50 am-1:25 pm

Nonstop1h 35m

$132

Cape GirardeauChicago

CGI - ORD

CGIORD

Cape Girardeau

Mon 12/8

9:30 am-11:10 am

Nonstop1h 40m

Chicago O'Hare Intl

Fri 12/12

11:50 am-1:25 pm

Nonstop1h 35m

$139

QuincyChicago

UIN - ORD

UINORD

Quincy Regional

Wed 11/5

9:50 am-11:10 am

Nonstop1h 20m

Chicago O'Hare Intl

Sun 11/9

2:00 pm-3:20 pm

Nonstop1h 20m

$143

QuincyChicago

UIN - ORD

UINORD

Quincy Regional

Thu 11/6

9:50 am-11:10 am

Nonstop1h 20m

Chicago O'Hare Intl

Mon 11/10

7:30 pm-8:50 pm

Nonstop1h 20m

$145

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Sat 12/6

6:42 pm-8:12 pm

Nonstop1h 30m

Chicago O'Hare Intl

Sun 12/7

2:14 pm-3:40 pm

Nonstop1h 26m

$153

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/21

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to O'Hare Intl

Have a flexible travel schedule? Discover the best time to fly to O'Hare Intl from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Chicago O'Hare Intl Airport

What is the cheapest month to book a flight from Missouri to Chicago O'Hare Intl Airport?

Currently, September is the cheapest month in which you can book a flight from Missouri to Chicago O'Hare Intl Airport (average of $62). Flying from Missouri to Chicago O'Hare Intl Airport in August is currently the most expensive (average of $142). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to ORD?

Find hourly flight availability from Missouri to O'Hare Intl. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 23, 2025.

A simple way to save on the total cost of your ticket is to fly from Missouri to Chicago O'Hare Intl Airport in the morning. If you’re flexible enough to do this you can expect to save up to 42% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Missouri to Chicago O'Hare Intl Airport?

Use this chart to determine the cheapest time to fly round-trip from Missouri to O'Hare Intl. Price data was last updated on October 19, 2025.

Travelers seeking maximum savings on their Missouri to Chicago O'Hare Intl Airport flight should consider departing on Thursday at noon when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Missouri to Chicago O'Hare Intl Airport

Explore weekly flight availability from Missouri to O'Hare Intl. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated October 23, 2025.

The most flights from USMO to ORD are scheduled on a Thursday (72 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (7 on average).

How much does it cost to fly round-trip from Missouri to Chicago O'Hare Intl Airport?

Related info for your journey

Find useful and relevant information for your journey from Missouri to O'Hare Intl. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Chicago O'Hare Intl Airport?

    Departing from Missouri to Chicago O'Hare Intl Airport will take you 1h 20m. The distance between Missouri and Chicago O'Hare Intl Airport is about 222 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Chicago O'Hare Intl Airport one-way?

    $51 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Contour and Southwest, with prices starting from $54 and $113, respectively.

  • What are the most popular routes from Missouri to Chicago O'Hare Intl Airport?

    The most popular route from Missouri to Chicago O'Hare Intl Airport is Kansas City - Chicago O'Hare Intl. You may also consider Lambert-St Louis - Chicago O'Hare Intl or Columbia Regional - Chicago O'Hare Intl.

  • What are the most reliable airlines from Missouri to Chicago O'Hare Intl Airport?

    No one likes to see their flight delayed. When booking a flight from Missouri to Chicago O'Hare Intl Airport consider choosing Cathay Pacific (90%), Japan Airlines (85%) or Austrian Airlines (85%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Missouri to Chicago O'Hare Intl Airport?

    Looking at all options, your cheapest flight can be booked for $104. While the most popular route (Kansas City - Chicago O'Hare Intl) can be booked for $109 on average, our data indicates $848 when flying from Missouri to Chicago O'Hare Intl Airport.

  • Can I find deals for flights from Missouri to O'Hare Intl that include hotel bookings?

    Yes. In addition to deals on Missouri to O'Hare Intl flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to O'Hare Intl?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to O'Hare Intl.

  • Can I find deals for business class flights from Missouri to O'Hare Intl?

    Yes. Cheapflights offers flight deals from Missouri to O'Hare Intl by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Chicago O'Hare Intl Airport?

    Currently, September is the cheapest month in which you can book a flight from Missouri to Chicago O'Hare Intl Airport (average of $62). Flying from Missouri to Chicago O'Hare Intl Airport in August is currently the most expensive (average of $142). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago O'Hare Intl Airport?

Book flights to Chicago O'Hare Intl Airport if you plan to visit one of these locations
Schaumburg
Rosemont
Skokie
Des Plaines
Gurnee
Hoffman Estates
Elgin
Oak Brook
Elk Grove Village
Beloit
Rockford
Naperville
Racine
Downers Grove
Orland Park
Merrillville
Bridgeview
Warrenville
Joliet
Waukegan

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to O'Hare Intl

See prices for flight routes from nearby airports that may be better suited for you.
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Philadelphia to Midway flights
Newark to Midway flights
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Dulles Intl to Midway flights
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Minneapolis to Midway flights
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Santa Ana to O'Hare Intl flights
Hobby to O'Hare Intl flights
Los Angeles to Midway flights
Denver to Midway flights
Love Field to O'Hare Intl flights
Reagan-National to Midway flights
San Francisco to Midway flights
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Tampa to O'Hare Intl flights
Hobby to Midway flights
Portland to O'Hare Intl flights
Fort Lauderdale to O'Hare Intl flights
Raleigh to O'Hare Intl flights
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Seattle to Midway flights
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Orlando to Midway flights
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Top 5 airlines flying from Missouri to O'Hare Intl

Discover the top 5 airlines that operate flights from Missouri to O'Hare Intl. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$114Average$301FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$116Average$340FlexibilityNo cancel feeOn-time69%
FrontierCheapest$118Average$182FlexibilityNo cancel feeOn-time62%
ContourCheapest$123Average$161FlexibilityNo cancel feeOn-timeN/A
Southern / MokuleleCheapest$140Average$221FlexibilityNo cancel feeOn-timeN/A

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