Cheap flights from Missouri (MO) to Chicago (CHI)

Know your dates, get live prices in seconds:

From
To
Depart
–
Return
Any month
Compare vs. Cheapflights |
From
To
Depart
Depart
Time
Anytime
From
To
Depart
Depart
Time
Anytime
From
To
Depart
Depart
Time
Anytime
From
To
Depart
Depart
Time
Anytime
From
To
Depart
Depart
Time
Anytime
From
To
Depart
Depart
Time
Anytime
Add another flight clear all

We work with more than 300 partners to bring you better travel deals

Home Flights North America USA Illinois Chicago Cheap flights from Missouri to Chicago

How to find the cheapest flight from
Missouri to Chicago (CHI)

All the information you need to plan the best null to CHI flight in 2022: compare Missouri to Chicago flight prices with the expected peak season, weather and rainfall in Chicago.
When is the cheapest time to fly from Missouri to Chicago (MO - CHI)?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Chicago as you normally would.

How far in advance should I book a flight from Missouri to Chicago?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 33 days in advance, which can save you up to 51% on flights from Missouri to Chicago compared to booking the week you need them. Waiting 33 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $278. For sooner than that we have options available in the next 3 days from $367.

What is the cheapest month to fly from Missouri to Chicago?

September can be a great time to fly to Chicago from Missouri with a flight ticket averaging about $246. Cheapflights users have found deals in the month of September for as cheap as $154. The most expensive prices can be found in the month of March.

Cheap flights from Missouri to Chicago in August, September 2022

The best prices found for Missouri to CHI flights for August, September
3 Sep - 4 Sep
$146pp
MCI
Kansas City
United Airlines
Non-Stop
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
United Airlines
Non-Stop
MCI
Kansas City
3 Sep - 4 Sep
$153pp
MCI
Kansas City
American Airlines
 
1 STOP
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
American Airlines
Non-Stop
MCI
Kansas City
3 Sep - 4 Sep
$161pp
MCI
Kansas City
American Airlines
 
1 STOP
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
American Airlines
 
1 STOP
MCI
Kansas City

Missouri to Chicago 2022 flight deals

Cheap flights to Chicago from Missouri found for this year
3 Sep - 4 Sep
$146pp
MCI
Kansas City
United Airlines
Non-Stop
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
United Airlines
Non-Stop
MCI
Kansas City
3 Sep - 4 Sep
$153pp
MCI
Kansas City
American Airlines
 
1 STOP
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
American Airlines
Non-Stop
MCI
Kansas City
3 Sep - 4 Sep
$161pp
MCI
Kansas City
American Airlines
 
1 STOP
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
American Airlines
 
1 STOP
MCI
Kansas City

Cheap American Airlines flights from Missouri to Chicago

3 Sep - 4 Sep
$153pp
MCI
Kansas City
American Airlines
 
1 STOP
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
American Airlines
Non-Stop
MCI
Kansas City
3 Sep - 4 Sep
$161pp
MCI
Kansas City
American Airlines
 
1 STOP
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
American Airlines
 
1 STOP
MCI
Kansas City
4 Sep - 10 Sep
$172pp
MCI
Kansas City
American Airlines
Non-Stop
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
American Airlines
Non-Stop
MCI
Kansas City

Cheap United Airlines flights from Missouri to Chicago

3 Sep - 4 Sep
$146pp
MCI
Kansas City
United Airlines
Non-Stop
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
United Airlines
Non-Stop
MCI
Kansas City
9 Sep - 12 Sep
$190pp
CGI
Cape Girardeau
United Airlines
Non-Stop
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
United Airlines
Non-Stop
CGI
Cape Girardeau
3 Sep - 9 Sep
$193pp
MCI
Kansas City
United Airlines
Non-Stop
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
United Airlines
Non-Stop
MCI
Kansas City

Non-stop flights to Chicago from Missouri

Save time with Missouri to Chicago direct flight deals
3 Sep - 4 Sep
$146pp
MCI
Kansas City
United Airlines
Non-Stop
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
United Airlines
Non-Stop
MCI
Kansas City
4 Sep - 10 Sep
$172pp
MCI
Kansas City
American Airlines
Non-Stop
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
American Airlines
Non-Stop
MCI
Kansas City
3 Sep - 30 Sep
$172pp
STL
Lambert-St Louis
American Airlines
Non-Stop
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
American Airlines
Non-Stop
STL
Lambert-St Louis

Last minute flights from Missouri to Chicago

Late deals on round-trip flights to Chicago from Missouri, departing today and this week
15 Aug - 27 Aug
$248pp
STL
Lambert-St Louis
Multiple Airlines
 
1 STOP
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
American Airlines
Non-Stop
STL
Lambert-St Louis
14 Aug - 6 Sep
$252pp
JLN
Joplin
United Airlines
Non-Stop
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
United Airlines
Non-Stop
JLN
Joplin
15 Aug - 27 Aug
$257pp
STL
Lambert-St Louis
Multiple Airlines
 
1 STOP
ORD
Chicago O'Hare Intl
ORD
Chicago O'Hare Intl
American Airlines
 
1 STOP
STL
Lambert-St Louis

One-way flights to Chicago from Missouri

The cheapest one-way flights from Missouri to Chicago
4:21 am - 5:51 am
United Airlines
Nonstop
1h 30m
STL - ORD
United Airlines
$73
United
2:30 am - 8:45 am
Delta
1 Stop
6h 15m
MCI - ORD
Delta
$82
Delta
8:50 am - 12:01 pm
Spirit Airlines
2 Stops
27h 11m
STL - ORD
Spirit Airlines
$100
mytrip.com

Related info for your journey

Useful info, stats and facts about <span class="emphasized">Missouri</span> to <span class="emphasized">Chicago</span> flights.

Flight FAQs

From Missouri to Chicago

Which airlines flying from Missouri to Chicago have flexible cancellations due to COVID-19?

United Airlines, American Airlines, and Delta are some of the carriers that may have flexible cancellation policies. You can use our site to filter for other airlines that may also have this kind of flexibility.

Can I find flights from Missouri to Chicago for under $200 on Cheapflights?

Yes, there are multiple flights from Missouri to Chicago for under $200. The cheapest flight booked recently is on United Airlines for just $146, but on average you can expect to pay $180.

Are there nonstop flights from Missouri to Chicago for under $200 on Cheapflights?

Cheapflights has at least 20 direct flights from Missouri to Chicago under $200. A good price for a nonstop flight from Missouri to Chicago is less than $199.

Are there last-minute flights available from Missouri to Chicago for under $300?

There are currently 20+ open flights from Missouri to Chicago within the next 7 days for less than $300.

What days are nonstop flights available from Missouri to Chicago?

Nonstop flights are available for this route on the following days: Monday, Tuesday, Wednesday, Thursday, Friday, Saturday.

How many flights depart from Missouri to Chicago on average per day?

6 flight departures from Missouri to Chicago per day on average.
Morning (6am - Noon) - 67% of flight departures
Afternoon (Noon - 6pm) - 33% of flight departures

How long is the flight from Missouri to Chicago?

United Airlines, American Airlines, and Delta can get you from Missouri to Chicago in just under 1h 42m. Your travel time can differ by up to 4h 32m. Missouri and Chicago are separated by a distance of 259 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines to fly from Missouri to Chicago one-way?

One-way options have recently been found by users for as low as $64 on Frontier. Other airlines that offer cheap prices include United Airlines from $73 and Delta from $82 one-way.

What are the most popular airlines that fly from Missouri to Chicago?

Consider Train, Bus or Air Choice One when booking your flight. These represent the most popular airlines when flying from Missouri to Chicago.

What are the cheapest flights from Missouri to Chicago?

The cheapest flight price from Missouri to Chicago is $88. On average you can expect to pay $395. The most popular route, (Kansas City - Chicago O'Hare Intl), can usually be booked for $172.

What are the most popular routes from Missouri to Chicago?

When deciding which route to take from Missouri to Chicago consider Kansas City - Chicago O'Hare Intl, Kansas City - Chicago Midway or Lambert-St Louis - Chicago O'Hare Intl as they are the most popular.

What are the most reliable airlines from Missouri to Chicago?

Consider Finnair (100%), Air Wisconsin (100%) or SkyWest Airlines (95%) when booking your flight. These represent the most reliable airlines when flying from Missouri to Chicago.

Related searches

Flights to Chicago from Missouri
Flights to Missouri Flights to Chicago Flights from Chicago

Rent a Car

Car Rentals in Chicago Car Rentals in Illinois Car Rentals at O'Hare Intl Car Rentals at Midway Car Rentals at Rockford

COVID Restrictions

View COVID Travel Restrictions for Chicago, IL

Do I need a COVID test to fly to Chicago from Missouri?

Information is based on travel restrictions for travel to Chicago within the United States

Most visitors from Missouri need to provide a negative COVID-19 test result and/or quarantine to enter Chicago.

COVID-19 testing requirements
Visitors from Missouri are not required to present a negative COVID-19 PCR test or antigen result upon entering Chicago.

Quarantine requirements
Visitors from Missouri are not required to quarantine after entering Chicago.

Do I need a test to fly back to Missouri from Chicago?

Returning to Missouri from Chicago

COVID-19 testing requirements
Visitors from Chicago are not required to present a negative COVID-19 PCR test or antigen result upon entering Missouri.

Quarantine requirements
Visitors from Chicago are not required to quarantine after entering Missouri.

Hide COVID Travel Restrictions for Chicago, IL

Departure points for flights from Missouri to Chicago

Select to see more specific information for flights to Chicago from all departure points in Missouri.
Show more

Top 5 airlines flying from Missouri to Chicago

The chart below displays the airlines Cheapflights users traveling from Missouri to Chicago choose most often. Cheapest and average prices are based on aggregated data from the past 12 months.
Airline Cheapest Average Flexibility On-time COVID-19 safety
Juneyao Airlines 		$16 $25 No cancel fee 66%

We couldn't confirm the COVID-19 safety measures taken by Juneyao Airlines. Please check directly on their website for additional information.
Air Choice One 		$70 $74 No cancel fee N/A

We couldn't confirm the COVID-19 safety measures taken by Air Choice One. Please check directly on their website for additional information.
Delta 		$72 $286 No cancel fee N/A
United Airlines 		$76 $255 No cancel fee 69%
American Airlines 		$99 $297 No cancel fee 71%

Popular flight searches

Check out other popular destinations found by fellow travelers in 2022.
Home Flights North America USA Illinois Chicago Cheap flights from Missouri to Chicago