$69+ Cheap flights from Missouri to Illinois
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ORD
May 31 — Jun 71
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to IllinoisExplore the most affordable flight options available from Missouri to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
Explore the most affordable flight options available from Missouri to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:21 am
STL
- MDW
1 stop6h 58m
Delta
Wed 6/36:23 am
MDW
- STL
1 stop5h 57m
Delta
Deal found 4/27![Delta logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:33 pm
STL
- ORD
2 stops18h 04m
Frontier
Thu 5/286:55 am
ORD
- STL
1 stop10h 38m
Frontier
Deal found 4/26![Frontier logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:31 pm
STL
- ORD
1 stop13h 32m
Multiple Airlines
Fri 6/126:15 am
ORD
- STL
1 stop12h 03m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:27 pm
STL
- ORD
2 stops14h 55m
Multiple Airlines
Wed 6/31:29 pm
ORD
- STL
1 stop28h 04m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$188
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:25 am
STL
- ORD
2 stops8h 49m
Delta
Sat 6/68:10 am
ORD
- STL
1 stop6h 08m
Delta
Deal found 4/27![Delta logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:24 pm
MCI
- STL
1 stop23h 09m
Frontier
Fri 6/54:19 pm
STL
- MCI
2 stops25h 10m
Frontier
Deal found 4/28![Frontier logo]()
$190
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:20 am
STL
- MDW
Nonstop1h 10m
Southwest
Mon 5/259:00 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 4/29![Southwest logo]()
$191
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:00 am
STL
- ORD
Nonstop1h 29m
American Airlines
Sat 5/307:05 am
ORD
- STL
Nonstop1h 27m
American Airlines
Deal found 4/30![American Airlines logo]()
$191
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:00 am
STL
- ORD
Nonstop1h 29m
American Airlines
Mon 5/2512:40 pm
ORD
- STL
Nonstop1h 26m
American Airlines
Deal found 4/30![American Airlines logo]()
$192
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:35 am
STL
- MDW
Nonstop1h 10m
Southwest
Thu 5/2111:40 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 4/28![Southwest logo]()
$199
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:54 am
JLN
- ORD
Nonstop1h 58m
United Airlines
Mon 9/2111:29 am
ORD
- JLN
Nonstop1h 49m
United Airlines
Deal found 4/28![United Airlines logo]()
$201
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:30 am
STL
- MDW
1 stop5h 35m
Southwest
Thu 6/46:00 pm
MDW
- STL
Nonstop1h 10m
Southwest
Deal found 4/28![Southwest logo]()
$201
Best flights from Missouri to IllinoisDiscover carefully curated flight deals from Missouri to Illinois that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
Discover carefully curated flight deals from Missouri to Illinois that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3010:55 am
STL
- MDW
2 stops6h 15m
Southwest
Sat 6/68:10 am
MDW
- STL
1 stop5h 55m
Southwest
Deal found 4/30![Southwest logo]()
$216
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:01 pm
STL
- ORD
1 stop4h 58m
Delta
Sat 6/61:44 pm
ORD
- STL
2 stops9h 37m
Delta
Deal found 4/28![Delta logo]()
$216
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/119:23 am
STL
- ORD
Nonstop1h 37m
United Airlines
Tue 6/167:05 am
ORD
- STL
Nonstop1h 36m
United Airlines
Deal found 4/30![United Airlines logo]()
$237
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:47 pm
COU
- ORD
Nonstop1h 47m
American Airlines
Sun 6/284:44 pm
ORD
- COU
Nonstop1h 33m
American Airlines
Deal found 4/27![American Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:24 pm
MCI
- STL
1 stop14h 31m
Frontier
Fri 6/54:19 pm
STL
- MCI
2 stops21h 30m
Frontier
Deal found 4/30![Frontier logo]()
$293
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:40 am
STL
- MDW
Nonstop1h 10m
Southwest
Mon 6/19:30 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 4/27![Southwest logo]()
$226
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/138:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Sat 6/209:15 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 4/30![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:32 pm
COU
- ORD
Nonstop1h 50m
American Airlines
Sat 6/64:36 pm
ORD
- COU
Nonstop1h 33m
American Airlines
Deal found 4/27![American Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:45 am
STL
- MDW
1 stop5h 57m
Delta
Mon 6/15:08 pm
MDW
- STL
1 stop4h 30m
Delta
Deal found 4/27![Delta logo]()
$245
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:45 pm
STL
- MDW
Nonstop1h 05m
Southwest
Thu 5/289:30 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 4/30![Southwest logo]()
$234
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:25 pm
COU
- ORD
Nonstop1h 40m
United Airlines
Sat 5/308:45 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 4/28![United Airlines logo]()
$239
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:05 pm
COU
- ORD
Nonstop1h 41m
United Airlines
Sat 8/89:15 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 4/29![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:21 am
STL
- ORD
2 stops6h 43m
Delta
Wed 6/245:57 pm
ORD
- STL
1 stop5h 26m
Delta
Deal found 4/28![Delta logo]()
$273
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:30 am
COU
- ORD
Nonstop1h 43m
United Airlines
Sat 8/1512:55 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Deal found 4/28![United Airlines logo]()
$239
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Sat 6/278:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Deal found 4/29![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:21 am
STL
- ORD
2 stops6h 35m
Delta
Thu 5/282:00 pm
ORD
- STL
2 stops9h 21m
Delta
Deal found 4/28![Delta logo]()
$295
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/92:05 pm
MCI
- MDW
1 stop2h 55m
Southwest
Wed 6/1011:25 am
MDW
- MCI
1 stop3h 50m
Southwest
Deal found 4/29![Southwest logo]()
$300
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/209:06 am
JLN
- ORD
Nonstop1h 54m
United Airlines
Sun 5/2411:32 am
ORD
- JLN
Nonstop1h 50m
United Airlines
Deal found 4/29![United Airlines logo]()
$241
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/149:24 am
STL
- ORD
1 stop8h 14m
American Airlines
Sat 7/186:47 pm
ORD
- STL
1 stop5h 10m
American Airlines
Deal found 4/30![American Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:52 pm
SGF
- ORD
1 stop5h 07m
Delta
Mon 5/188:10 am
ORD
- SGF
1 stop6h 27m
Delta
Deal found 4/29![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:15 pm
STL
- MDW
Nonstop1h 05m
Southwest
Sat 8/296:35 am
MDW
- STL
Nonstop1h 10m
Southwest
Deal found 4/25![Southwest logo]()
$306
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:54 am
JLN
- ORD
Nonstop1h 58m
United Airlines
Wed 6/311:32 am
ORD
- JLN
Nonstop1h 50m
United Airlines
Deal found 4/29![United Airlines logo]()
$241
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:52 pm
SGF
- ORD
1 stop5h 07m
Delta
Sun 5/177:07 am
ORD
- SGF
1 stop7h 30m
Delta
Deal found 4/28![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:20 am
MCI
- MDW
Nonstop1h 25m
Southwest
Wed 7/157:50 am
MDW
- MCI
Nonstop1h 30m
Southwest
Deal found 4/29![Southwest logo]()
$309
This KAYAK deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:09 pm
SGF
- ORD
Nonstop1h 59m
American Airlines
Thu 5/215:10 am
ORD
- SGF
1 stop5h 47m
American Airlines
Deal found 4/27![American Airlines logo]()
$377
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:52 pm
SGF
- ORD
1 stop5h 07m
Delta
Sun 5/177:07 am
ORD
- SGF
1 stop7h 30m
Delta
Deal found 4/28![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/278:54 am
JLN
- ORD
Nonstop1h 58m
United Airlines
Mon 9/2111:29 am
ORD
- JLN
Nonstop1h 49m
United Airlines
Deal found 4/29![United Airlines logo]()
$251
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2110:15 am
STL
- MDW
1 stop3h 50m
Southwest
Mon 5/259:30 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 4/28![Southwest logo]()
$320
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:52 pm
SGF
- ORD
1 stop5h 07m
Delta
Sat 5/161:44 pm
ORD
- SGF
2 stops8h 35m
Delta
Deal found 4/29![Delta logo]()
$304
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:23 am
COU
- ORD
Nonstop1h 42m
United Airlines
Sun 6/710:57 pm
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 4/29![United Airlines logo]()
$252
Last-minute flights from Missouri to IllinoisDiscover last-minute flight deals from Missouri to Illinois. Data last updated May 1, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Illinois. Data last updated May 1, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:23 pm
STL
- ORD
1 stop11h 32m
Frontier
Mon 5/115:30 pm
ORD
- STL
1 stop6h 51m
Frontier
Deal found 4/27![Frontier logo]()
$202
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/191:27 pm
STL
- ORD
1 stop5h 14m
Delta
Sat 5/301:44 pm
ORD
- STL
2 stops9h 37m
Delta
Deal found 4/27![Delta logo]()
$189
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:35 am
STL
- MDW
Nonstop1h 10m
Southwest
Thu 5/2111:40 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 4/28![Southwest logo]()
$199
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/209:06 am
JLN
- ORD
Nonstop1h 54m
United Airlines
Sun 5/2411:32 am
ORD
- JLN
Nonstop1h 50m
United Airlines
Deal found 4/28![United Airlines logo]()
$201
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:20 am
STL
- MDW
Nonstop1h 10m
Southwest
Mon 5/259:00 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 4/29![Southwest logo]()
$191
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:00 am
STL
- ORD
Nonstop1h 29m
American Airlines
Sat 5/307:05 am
ORD
- STL
Nonstop1h 27m
American Airlines
Deal found 4/30![American Airlines logo]()
$191
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:00 am
STL
- ORD
Nonstop1h 29m
American Airlines
Mon 5/2512:40 pm
ORD
- STL
Nonstop1h 26m
American Airlines
Deal found 4/30![American Airlines logo]()
$192
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:02 pm
STL
- ORD
Nonstop1h 43m
American Airlines
Mon 5/2510:40 pm
ORD
- STL
Nonstop1h 14m
American Airlines
Deal found 4/26![American Airlines logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:33 pm
STL
- ORD
2 stops18h 04m
Frontier
Tue 6/21:50 pm
ORD
- STL
1 stop19h 05m
Frontier
Deal found 4/26![Frontier logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:27 pm
STL
- ORD
2 stops14h 55m
Multiple Airlines
Wed 6/31:29 pm
ORD
- STL
1 stop28h 04m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$188
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:30 am
STL
- MDW
1 stop5h 35m
Southwest
Thu 6/46:00 pm
MDW
- STL
Nonstop1h 10m
Southwest
Deal found 4/28![Southwest logo]()
$201
This Frontier deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:19 pm
STL
- ORD
1 stop6h 54m
Frontier
Sun 5/316:55 am
ORD
- STL
1 stop10h 38m
Frontier
Deal found 4/30![Frontier logo]()
$201
One-way flights from Missouri to IllinoisSearch for one-way flight options from Missouri to Illinois. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
Search for one-way flight options from Missouri to Illinois. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/263:45 pm
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 4/29![Southwest logo]()
$69
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
STL
- ORD
Nonstop1h 29m
United Airlines
Deal found 4/29![United Airlines logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:45 pm
MCI
- STL
1 stop5h 38m
Frontier
Deal found 4/29![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/234:19 pm
STL
- ORD
1 stop6h 54m
Frontier
Deal found 4/26![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:31 pm
STL
- MDW
1 stop16h 38m
Frontier
Deal found 4/29![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:33 pm
STL
- ORD
1 stop13h 22m
Frontier
Deal found 4/29![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:24 pm
MCI
- ORD
1 stop13h 31m
Frontier
Deal found 4/27![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:33 pm
STL
- MDW
1 stop27h 29m
Frontier
Deal found 4/29![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:33 pm
STL
- ORD
1 stop13h 22m
Frontier
Deal found 4/28![Frontier logo]()
$76
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:00 am
STL
- MDW
1 stop6h 00m
Delta
Deal found 4/28![Delta logo]()
$79
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1010:51 am
STL
- ORD
1 stop6h 13m
Delta
Deal found 4/27![Delta logo]()
$79
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/185:27 pm
STL
- MDW
1 stop28h 35m
Frontier
Deal found 4/28![Frontier logo]()
$82
Find flight deals from Missouri to Illinois
Keep the following information in mind while searching for Missouri to Illinois flight deals. Data was last updated May 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $184 (Delta) |
One-way from | $69 (Southwest) |
Popular in | January |
Cheapest in | August |
Average price | $279 |
Good round-trip deal | $138 or less |
Good one-way deal | $59 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
Use the filters below to find and compare flights from Missouri to Illinois that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisChicago
STL - MDW
STLMDW
Lambert-St Louis
Sat 5/30
10:55 am-5:10 pm
2 stops6h 15m
Chicago Midway
Sat 6/6
8:10 am-2:05 pm
1 stop5h 55m
$216
St. LouisChicago
STL - ORD
STLORD
Lambert-St Louis
Thu 6/4
7:01 pm-11:59 pm
1 stop4h 58m
Chicago O'Hare Intl
Sat 6/6
1:44 pm-11:21 pm
2 stops9h 37m
$216
St. LouisChicago
STL - MDW
STLMDW
Lambert-St Louis
Mon 5/25
5:40 am-6:50 am
Nonstop1h 10m
Chicago Midway
Mon 6/1
9:30 pm-10:45 pm
Nonstop1h 15m
$226
St. LouisChicago
STL - MDW
STLMDW
Lambert-St Louis
Tue 5/26
8:45 pm-9:50 pm
Nonstop1h 05m
Chicago Midway
Thu 5/28
9:30 pm-10:45 pm
Nonstop1h 15m
$234
St. LouisChicago
STL - ORD
STLORD
Lambert-St Louis
Thu 6/11
9:23 am-11:00 am
Nonstop1h 37m
Chicago O'Hare Intl
Tue 6/16
7:05 am-8:41 am
Nonstop1h 36m
$237
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Thu 6/25
6:47 pm-8:34 pm
Nonstop1h 47m
Chicago O'Hare Intl
Sun 6/28
4:44 pm-6:17 pm
Nonstop1h 33m
$239
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Sat 6/13
8:00 am-9:40 am
Nonstop1h 40m
Chicago O'Hare Intl
Sat 6/20
9:15 am-10:48 am
Nonstop1h 33m
$239
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Fri 5/22
6:32 pm-8:22 pm
Nonstop1h 50m
Chicago O'Hare Intl
Sat 6/6
4:36 pm-6:09 pm
Nonstop1h 33m
$239
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Thu 5/28
3:25 pm-5:05 pm
Nonstop1h 40m
Chicago O'Hare Intl
Sat 5/30
8:45 am-10:18 am
Nonstop1h 33m
$239
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Thu 8/6
3:05 pm-4:46 pm
Nonstop1h 41m
Chicago O'Hare Intl
Sat 8/8
9:15 am-10:48 am
Nonstop1h 33m
$239
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Illinois
Have a flexible travel schedule? Discover the best time to fly to Illinois from Missouri with our price prediction graph.
STL-MDW
STL-ORD
COU-ORD
MCI-STL
MCI-MDW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Illinois
USMO-USIL
STL-MDW
STL-ORD
COU-ORD
MCI-STL
How far ahead should I book a flight from Missouri to Illinois?
The price you pay for your flight from Missouri to Illinois may vary depending on when you book. For the best chance of a lower fare, look to book 83 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Missouri to Illinois?
Currently, August is the cheapest month in which you can book a flight from Missouri to Illinois (average of $61). Flying from Missouri to Illinois in February is currently the most expensive (average of $117). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to IL?
Find hourly flight availability from Missouri to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2026.
When flying from Missouri to Illinois, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 35% versus a flight in the evening.
What is the cheapest day to fly from Missouri to Illinois?
Use this chart to determine the cheapest time to fly round-trip from Missouri to Illinois. Price data was last updated on April 25, 2026.
Travelers seeking maximum savings on their Missouri to Illinois flight should consider departing on Friday at noon when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Missouri to Illinois
Explore weekly flight availability from Missouri to Illinois. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 1, 2026.
The most flights from USMO to USIL are scheduled on a Wednesday (77 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (28 on average).
How much does it cost to fly round-trip from Missouri to Illinois?
Reviews of airlines servicing Illinois
Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated May 1, 2026.
Read reviews from past customers who have flown Southwest,Contour, andUnited Airlines from Missouri to Illinois. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Missouri to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Missouri to Illinois
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Illinois by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Illinois by cabin class
Find flights from Missouri to Illinois, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Illinois flights
Browse other Missouri and Illinois flight options. Last updated on May 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Illinois
Find the right flight back to Missouri after your stay in Illinois
Missouri to Illinois flights
Consider these flights traveling from Missouri to Illinois.
Top 6 airlines flying from Missouri to Illinois
Discover the top 6 airlines that operate flights from Missouri to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$62 | Average$160 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$97 | Average$381 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$117 | Average$412 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$117 | Average$344 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$140 | Average$212 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$143 | Average$176 | FlexibilityNo cancel fee | On-time62% |