$59+ Cheap flights from Illinois to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — STL
Jun 2 — Jun 91
Round-trip
1 adult, Economy
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Cheapest flights from Illinois to MissouriExplore the most affordable flight options available from Illinois to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 3, 2026.
Explore the most affordable flight options available from Illinois to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 3, 2026.
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Sun 6/79:50 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/29![Contour logo]()
$124
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2112:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Sun 5/249:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/28![Contour logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:33 pm
STL
- MCI
1 stop22h 56m
Frontier
Mon 6/86:24 pm
MCI
- STL
1 stop23h 06m
Frontier
Deal found 5/1![Frontier logo]()
$159
This Contour deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/111:15 am
ORD
- CGI
Nonstop1h 40m
Contour
Wed 9/21:30 pm
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/28![Contour logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:08 pm
STL
- MCI
1 stop17h 41m
Frontier
Tue 6/22:34 pm
MCI
- STL
2 stops18h 21m
Frontier
Deal found 4/28![Frontier logo]()
$185
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/133:55 pm
ORD
- CGI
Nonstop1h 40m
Contour
Sun 5/179:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/28![Contour logo]()
$210
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Thu 5/149:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/28![Contour logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:33 pm
STL
- MCI
1 stop22h 56m
Frontier
Tue 6/22:34 pm
MCI
- STL
1 stop28h 49m
Frontier
Deal found 4/30![Frontier logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:33 pm
STL
- MCI
1 stop22h 56m
Frontier
Tue 6/161:45 pm
MCI
- STL
2 stops19h 07m
Frontier
Deal found 5/2![Frontier logo]()
$217
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Mon 5/189:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/29![Contour logo]()
$229
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/214:25 pm
ORD
- COU
Nonstop1h 37m
American Airlines
Sun 5/246:32 pm
COU
- ORD
Nonstop1h 50m
American Airlines
Deal found 4/29![American Airlines logo]()
$238
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Tue 5/263:25 pm
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 5/1![United Airlines logo]()
$239
Best flights from Illinois to MissouriDiscover carefully curated flight deals from Illinois to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 3, 2026.
Discover carefully curated flight deals from Illinois to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 3, 2026.
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Sun 6/79:50 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/29![Contour logo]()
$124
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:00 pm
ORD
- COU
Nonstop1h 33m
United Airlines
Sat 7/118:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 5/1![United Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/214:15 pm
ORD
- STL
1 stop8h 00m
Southwest
Mon 5/257:35 am
STL
- ORD
1 stop5h 15m
Southwest
Deal found 4/29![Southwest logo]()
$246
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/64:35 pm
ORD
- COU
Nonstop1h 29m
American Airlines
Sun 8/96:37 pm
COU
- ORD
Nonstop1h 52m
American Airlines
Deal found 5/1![American Airlines logo]()
$254
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:35 am
ORD
- STL
1 stop5h 59m
Delta
Tue 6/167:08 am
STL
- ORD
1 stop5h 28m
Delta
Deal found 4/30![Delta logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1512:10 pm
ORD
- CGI
Nonstop1h 40m
Multiple Airlines
Mon 6/223:30 pm
CGI
- ORD
2 stops13h 37m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$355
This Booking.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2412:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Sun 7/269:50 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/28![Contour logo]()
$210
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/133:55 pm
ORD
- CGI
Nonstop1h 40m
Contour
Sun 5/179:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/28![Contour logo]()
$210
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:45 am
ORD
- COU
Nonstop1h 33m
United Airlines
Mon 5/258:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 4/28![United Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:15 pm
MDW
- STL
1 stop3h 45m
Southwest
Fri 9/187:40 am
STL
- MDW
1 stop5h 10m
Southwest
Deal found 4/29![Southwest logo]()
$257
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/303:50 pm
ORD
- COU
1 stop6h 30m
American Airlines
Wed 7/811:45 am
COU
- ORD
1 stop8h 44m
American Airlines
Deal found 5/1![American Airlines logo]()
$258
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Sat 6/610:48 am
COU
- ORD
Nonstop1h 41m
United Airlines
Deal found 5/2![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:06 pm
ORD
- STL
1 stop5h 53m
Delta
Mon 5/251:59 pm
STL
- ORD
1 stop6h 15m
Delta
Deal found 4/29![Delta logo]()
$265
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/13:45 pm
MDW
- STL
1 stop4h 45m
Southwest
Wed 7/83:45 pm
STL
- MDW
1 stop5h 50m
Southwest
Deal found 4/30![Southwest logo]()
$257
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/24:45 pm
ORD
- COU
1 stop6h 01m
American Airlines
Tue 7/75:19 pm
COU
- ORD
1 stop7h 24m
American Airlines
Deal found 5/2![American Airlines logo]()
$258
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Tue 6/911:23 am
COU
- ORD
Nonstop1h 42m
United Airlines
Deal found 4/30![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1712:45 pm
MDW
- SGF
1 stop5h 27m
Delta
Sun 6/213:30 pm
SGF
- MDW
1 stop6h 47m
Delta
Deal found 4/29![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:35 am
MDW
- STL
2 stops6h 20m
Southwest
Wed 6/311:30 am
STL
- MDW
1 stop3h 35m
Southwest
Deal found 4/28![Southwest logo]()
$259
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/912:45 pm
MDW
- SGF
1 stop5h 27m
Delta
Sat 6/134:08 pm
SGF
- MDW
1 stop6h 09m
Delta
Deal found 4/28![Delta logo]()
$269
This Contour deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1812:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Fri 5/229:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 5/2![Contour logo]()
$273
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1012:05 pm
ORD
- COU
1 stop6h 57m
American Airlines
Sat 7/117:16 am
COU
- ORD
1 stop7h 04m
American Airlines
Deal found 5/2![American Airlines logo]()
$273
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1910:57 pm
ORD
- COU
Nonstop1h 33m
United Airlines
Mon 6/223:05 pm
COU
- ORD
Nonstop1h 41m
United Airlines
Deal found 4/30![United Airlines logo]()
$253
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/198:30 am
ORD
- COU
Nonstop1h 36m
American Airlines
Mon 6/225:19 pm
COU
- ORD
1 stop7h 20m
American Airlines
Deal found 4/30![American Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:07 am
ORD
- SGF
1 stop7h 30m
Delta
Sat 6/612:07 pm
SGF
- ORD
1 stop6h 34m
Delta
Deal found 5/2![Delta logo]()
$284
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:50 am
MDW
- STL
Nonstop1h 15m
Southwest
Thu 5/2110:15 am
STL
- MDW
1 stop3h 50m
Southwest
Deal found 4/29![Southwest logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Thu 5/149:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 5/1![Contour logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2112:10 pm
ORD
- CGI
Nonstop1h 40m
Multiple Airlines
Sun 5/243:30 pm
CGI
- ORD
1 stop20h 34m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/262:00 pm
ORD
- SGF
2 stops8h 19m
Delta
Tue 6/23:22 pm
SGF
- ORD
1 stop7h 05m
Delta
Deal found 4/28![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:44 am
BMI
- MCI
1 stop4h 47m
United Airlines
Sun 10/46:00 am
MCI
- BMI
1 stop6h 50m
United Airlines
Deal found 4/28![United Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:35 am
MDW
- STL
2 stops6h 20m
Southwest
Thu 6/412:50 pm
STL
- MDW
1 stop4h 15m
Southwest
Deal found 4/29![Southwest logo]()
$289
Last-minute flights from Illinois to MissouriDiscover last-minute flight deals from Illinois to Missouri. Data last updated May 3, 2026 and is based on user searches.
Discover last-minute flight deals from Illinois to Missouri. Data last updated May 3, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Thu 5/149:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/28![Contour logo]()
$211
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/133:55 pm
ORD
- CGI
Nonstop1h 40m
Contour
Sun 5/179:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/28![Contour logo]()
$210
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Mon 5/189:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/29![Contour logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:10 pm
ORD
- CGI
Nonstop1h 40m
Multiple Airlines
Mon 5/183:30 pm
CGI
- ORD
1 stop23h 33m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$243
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2112:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Sun 5/249:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/28![Contour logo]()
$125
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/214:25 pm
ORD
- COU
Nonstop1h 37m
American Airlines
Sun 5/246:32 pm
COU
- ORD
Nonstop1h 50m
American Airlines
Deal found 4/29![American Airlines logo]()
$238
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/214:15 pm
ORD
- STL
1 stop8h 00m
Southwest
Mon 5/257:35 am
STL
- ORD
1 stop5h 15m
Southwest
Deal found 4/29![Southwest logo]()
$246
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Tue 5/263:25 pm
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 5/1![United Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:00 am
MDW
- STL
2 stops17h 57m
Multiple Airlines
Wed 5/275:27 pm
STL
- MDW
1 stop17h 45m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:08 pm
STL
- MCI
1 stop17h 41m
Frontier
Tue 6/22:34 pm
MCI
- STL
2 stops18h 21m
Frontier
Deal found 4/28![Frontier logo]()
$185
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:04 pm
ORD
- STL
Nonstop1h 26m
American Airlines
Fri 5/296:12 pm
STL
- ORD
1 stop5h 47m
American Airlines
Deal found 4/28![American Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:33 pm
STL
- MCI
1 stop22h 56m
Frontier
Tue 6/22:34 pm
MCI
- STL
1 stop28h 49m
Frontier
Deal found 4/30![Frontier logo]()
$214
One-way flights from Illinois to MissouriSearch for one-way flight options from Illinois to Missouri. Find affordable one-way fares based on user searches. Data last updated May 3, 2026.
Search for one-way flight options from Illinois to Missouri. Find affordable one-way fares based on user searches. Data last updated May 3, 2026.
This Booking.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 4/30![Contour logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:31 pm
STL
- MCI
1 stop22h 50m
Frontier
Deal found 5/2![Frontier logo]()
$65
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/168:20 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 4/29![Southwest logo]()
$69
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1711:00 pm
ORD
- STL
Nonstop1h 16m
American Airlines
Deal found 4/30![American Airlines logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1612:27 pm
MDW
- STL
1 stop20h 25m
Frontier
Deal found 4/29![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:08 pm
STL
- MCI
1 stop17h 41m
Frontier
Deal found 4/29![Frontier logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
MDW
- STL
1 stop26h 55m
Frontier
Deal found 4/29![Frontier logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:55 am
ORD
- STL
1 stop26h 00m
Frontier
Deal found 4/29![Frontier logo]()
$74
This Super.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/209:37 pm
ORD
- STL
1 stop21h 46m
Frontier
Deal found 4/29![Frontier logo]()
$75
This Frontier deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
MDW
- STL
1 stop11h 33m
Frontier
Deal found 4/28![Frontier logo]()
$76
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:55 am
ORD
- STL
1 stop10h 38m
Frontier
Deal found 4/29![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2912:04 pm
MDW
- STL
1 stop29h 26m
Frontier
Deal found 4/30![Frontier logo]()
$78
Find flight deals from Illinois to Missouri
Keep the following information in mind while searching for Illinois to Missouri flight deals. Data was last updated May 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $124 (Mytrip) |
One-way from | $59 (Booking.com) |
Popular in | January |
Cheapest in | December |
Average price | $283 |
Good round-trip deal | $61 or less |
Good one-way deal | $81 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Illinois to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 3, 2026.
Use the filters below to find and compare flights from Illinois to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Thu 6/4
12:10 pm-1:50 pm
Nonstop1h 40m
Cape Girardeau
Sun 6/7
9:50 am-11:35 am
Nonstop1h 45m
$124
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Fri 7/24
12:10 pm-1:50 pm
Nonstop1h 40m
Cape Girardeau
Sun 7/26
9:50 am-11:35 am
Nonstop1h 45m
$210
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Wed 5/13
3:55 pm-5:35 pm
Nonstop1h 40m
Cape Girardeau
Sun 5/17
9:45 am-11:30 am
Nonstop1h 45m
$210
Quickest round-trip
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 7/10
10:00 pm-11:33 pm
Nonstop1h 33m
Columbia Regional
Sat 7/11
8:00 am-9:40 am
Nonstop1h 40m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 5/21
8:45 am-10:18 am
Nonstop1h 33m
Columbia Regional
Mon 5/25
8:00 am-9:40 am
Nonstop1h 40m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Sat 5/30
8:08 pm-9:59 pm
Nonstop1h 51m
Columbia Regional
Sat 6/6
10:48 am-12:29 pm
Nonstop1h 41m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Tue 6/2
8:08 pm-9:59 pm
Nonstop1h 51m
Columbia Regional
Tue 6/9
11:23 am-1:05 pm
Nonstop1h 42m
$239
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Thu 5/21
4:15 pm-12:15 am
1 stop8h 00m
Lambert-St Louis
Mon 5/25
7:35 am-12:50 pm
1 stop5h 15m
$246
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 6/19
10:57 pm-12:30 am
Nonstop1h 33m
Columbia Regional
Mon 6/22
3:05 pm-4:46 pm
Nonstop1h 41m
$253
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 8/6
4:35 pm-6:04 pm
Nonstop1h 29m
Columbia Regional
Sun 8/9
6:37 pm-8:29 pm
Nonstop1h 52m
$254
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Illinois to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Illinois with our price prediction graph.
ORD-CGI
STL-MCI
MDW-STL
ORD-STL
ORD-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Illinois to Missouri
USIL-USMO
ORD-CGI
STL-MCI
MDW-STL
ORD-STL
How far ahead should I book a flight from Illinois to Missouri?
To ensure you get the cheapest price possible for a flight from Illinois to Missouri, you should look to book at least 78 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Illinois to Missouri?
Currently, September is the cheapest month in which you can book a flight from Illinois to Missouri (average of $68). Flying from Illinois to Missouri in May is currently the most expensive (average of $127). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IL to MO?
Find hourly flight availability from Illinois to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 3, 2026.
One of the essential ways to save on airfare from Illinois to Missouri is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 21% on airfare.
What is the cheapest day to fly from Illinois to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Illinois to Missouri. Price data was last updated on May 2, 2026.
Travelers seeking maximum savings on their Illinois to Missouri flight should consider departing on Friday afternoons when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Illinois to Missouri
Explore weekly flight availability from Illinois to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 3, 2026.
The most flights from USIL to USMO are scheduled on a Friday (80 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (50 on average).
How much does it cost to fly round-trip from Illinois to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated May 3, 2026.
Read reviews from past customers who have flown Southwest,Contour, andUnited Airlines from Illinois to Missouri. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Illinois to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Illinois to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Illinois to Missouri by cabin class
Find flights from Illinois to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Illinois and Missouri flights
Browse other Illinois and Missouri flight options. Last updated on May 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Illinois after your stay in Missouri
Illinois to Missouri flights
Consider these flights traveling from Illinois to Missouri.
Top 5 airlines flying from Illinois to Missouri
Discover the top 5 airlines that operate flights from Illinois to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$77 | Average$361 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$104 | Average$161 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$124 | Average$318 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$154 | Average$362 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$165 | Average$227 | FlexibilityNo cancel fee | On-timeN/A |