HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
O'Hare Intl

$89+ Cheap flights from Knoxville (TYS) to O'Hare Intl (ORD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ORD
May 21 — May 281
Thu 5/21
Thu 5/28
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to O'Hare Intl with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.
Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Chicago O'Hare Intl are usually found in August or April, booked 68 days in advance, depart on a Friday or Thursday and return on a Saturday

Cheap flight deals from Knoxville to O'Hare Intl

Cheapest flights from Knoxville to O'Hare Intl
Explore the most affordable flight options available from Knoxville to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 21, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:20 pm
TYS
-
ORD
1 stop9h 53m
Multiple Airlines
Wed 5/278:05 am
ORD
-
TYS
1 stop27h 08m
Multiple Airlines
Deal found 4/17$203
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:20 pm
TYS
-
ORD
1 stop5h 37m
Delta
Sat 9/191:15 pm
ORD
-
TYS
1 stop4h 02m
Delta
Deal found 4/20$213
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:40 pm
TYS
-
ORD
2 stops20h 23m
Multiple Airlines
Wed 6/107:52 am
ORD
-
TYS
1 stop9h 06m
Multiple Airlines
Deal found 4/16$215
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:40 pm
TYS
-
ORD
1 stop27h 19m
Multiple Airlines
Thu 5/218:05 am
ORD
-
TYS
2 stops31h 35m
Multiple Airlines
Deal found 4/16$218
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:56 am
TYS
-
ORD
1 stop10h 21m
Multiple Airlines
Wed 5/61:59 pm
ORD
-
TYS
2 stops24h 42m
Multiple Airlines
Deal found 4/16$223
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/133:05 pm
TYS
-
ORD
1 stop6h 09m
Delta
Sun 5/175:30 am
ORD
-
TYS
1 stop4h 39m
Delta
Deal found 4/20$225
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:32 pm
TYS
-
ORD
1 stop25h 00m
Multiple Airlines
Fri 5/157:33 pm
ORD
-
TYS
1 stop14h 33m
Multiple Airlines
Deal found 4/18$227
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:39 pm
TYS
-
ORD
1 stop19h 44m
Multiple Airlines
Sun 5/178:30 am
ORD
-
TYS
1 stop13h 03m
Multiple Airlines
Deal found 4/20$231
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:40 pm
TYS
-
ORD
1 stop27h 19m
Multiple Airlines
Tue 5/191:18 pm
ORD
-
TYS
1 stop27h 41m
Multiple Airlines
Deal found 4/17$232
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/101:02 pm
TYS
-
ORD
1 stop11h 13m
Multiple Airlines
Sat 6/137:52 pm
ORD
-
TYS
1 stop23h 37m
Multiple Airlines
Deal found 4/16$237

Find flight deals from Knoxville to O'Hare Intl

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to O'Hare Intl (ORD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$203
(Kiwi.com)

One-way from

$89
(Kiwi.com)

Popular in

October

Cheapest in

August

Average price

$256

Good round-trip deal

$383 or less

Good one-way deal

$201 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Chicago O'Hare Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Chicago O'Hare Intl flights.
Search Deals
From Knoxville McGhee Tyson to Chicago O'Hare Intl
Search Deals
One-way flight from Knoxville McGhee Tyson to Chicago O'Hare Intl
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($23 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a round-trip flight from Knoxville McGhee Tyson to Chicago O'Hare Intl.
Search Deals
Price to beat on a one-way flight from Knoxville McGhee Tyson to Chicago O'Hare Intl.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to O'Hare Intl that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 21, 2026.
Use the filters below to find and compare flights from Knoxville to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 7/8

3:54 pm-10:08 pm

1 stop7h 14m

Chicago O'Hare Intl

Mon 7/13

2:07 pm-9:38 pm

1 stop6h 31m

$269

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 7/3

3:54 pm-8:32 pm

1 stop5h 38m

Chicago O'Hare Intl

Tue 7/7

3:22 pm-9:58 pm

1 stop5h 36m

$269

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 9/18

4:00 pm-9:45 pm

1 stop6h 45m

Chicago O'Hare Intl

Mon 9/21

8:00 am-3:07 pm

1 stop6h 07m

$269

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Sun 5/24

5:40 am-8:39 am

1 stop3h 59m

Chicago O'Hare Intl

Tue 5/26

5:30 am-1:10 pm

1 stop6h 40m

$269
Quickest round-trip

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 6/12

7:43 pm-11:59 pm

1 stop5h 16m

Chicago O'Hare Intl

Tue 6/16

5:40 pm-11:54 pm

1 stop5h 14m

$269

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 5/21

6:35 am-12:50 pm

1 stop7h 15m

Chicago O'Hare Intl

Sun 5/24

2:00 pm-6:45 pm

1 stop3h 45m

$300

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Sun 7/19

3:54 pm-10:08 pm

1 stop7h 14m

Chicago O'Hare Intl

Fri 7/24

1:44 pm-7:53 pm

1 stop5h 09m

$309
Cheapest one-way

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Tue 6/2

1:59 pm-6:41 pm

1 stop5h 42m

$94

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Tue 6/2

5:05 pm-7:51 pm

2 stops27h 46m

$125

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 5/13

3:30 pm-8:26 pm

1 stop5h 56m

$130

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/20

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Compare providers for flights from Knoxville to O'Hare Intl

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to O'Hare Intl in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Chicago O'Hare Intl Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Chicago O'Hare Intl Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Chicago O'Hare Intl Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Chicago O'Hare Intl Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Chicago O'Hare Intl Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to O'Hare Intl

Have a flexible travel schedule? Discover the best time to fly to O'Hare Intl from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Chicago O'Hare Intl Airport

How far ahead should I book a flight from Knoxville to Chicago O'Hare Intl Airport?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to O'Hare Intl. Price data was last updated on April 17, 2026.

To ensure you get the cheapest price possible for a flight from Knoxville to Chicago O'Hare Intl Airport, you should look to book at least 23 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Knoxville to Chicago O'Hare Intl Airport?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Chicago O'Hare Intl Airport (average of $216). Flying from Knoxville to Chicago O'Hare Intl Airport in October is currently the most expensive (average of $371). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to ORD?

Find hourly flight availability from Knoxville to O'Hare Intl. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 21, 2026.

Unlike at noon, when flights are generally more expensive, you can save up to 27% on flights from Knoxville to Chicago O'Hare Intl Airport by exploring options for tickets in the morning.

What is the cheapest day to fly from Knoxville to Chicago O'Hare Intl Airport?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to O'Hare Intl. Price data was last updated on April 18, 2026.

Travelers seeking maximum savings on their Knoxville to Chicago O'Hare Intl Airport flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Knoxville to Chicago O'Hare Intl Airport?

Reviews of airlines servicing O'Hare Intl

Get insights into the airlines that provide service to O'Hare Intl. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to O'Hare Intl. Reviews last updated April 21, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Knoxville to Chicago O'Hare Intl Airport. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,613 reviews

Food

6.6

Crew

8.1

Comfort

7.3

Overall

7.4

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,613 reviews
United Airlines
7.4
Good
9,613 reviews

Food

6.6

Crew

8.1

Comfort

7.3

Overall

7.4

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.1
Good
11,645 reviews
United Airlines
7.4
Good
9,613 reviews

Food

6.6

Crew

8.1

Comfort

7.3

Overall

7.4

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Knoxville to O'Hare Intl. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Chicago O'Hare Intl?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson is the airport most travelers will use when flying to Chicago O'Hare Intl from Knoxville. Booking flights from McGhee Tyson (TYS) to Chicago O'Hare Intl should be relatively easy as there are 28 daily outbound flights to Chicago O'Hare Intl from 2 different airlines.

  • How long is the flight from Knoxville to Chicago O'Hare Intl Airport?

    A quick flight from Knoxville to Chicago O'Hare Intl Airport can take about 7h 14m. Delta provides one of the quickest options available for as low as $269. Airlines will cover a distance of 475 mi.

  • What are the cheapest airlines flying from Knoxville to Chicago O'Hare Intl Airport round-trip?

    According to our current data, American Airlines ($189), and United Airlines ($189) offers the cheapest pricing from Knoxville to Chicago O'Hare Intl Airport. Users have found that American Airlines is 34% cheaper than the other options available to this destination.

  • What are the most reliable airlines from Knoxville to Chicago O'Hare Intl Airport?

    The top 3 most reliable airlines when flying from Knoxville to Chicago O'Hare Intl Airport are Emirates (86%), ANA (78%) and Avianca (75%).

  • What are the cheapest flights from Knoxville to Chicago O'Hare Intl Airport?

    Looking at all options, your cheapest flight can be booked for $145. While the most popular route (Knoxville McGhee Tyson - Chicago O'Hare Intl) can be booked for $249 on average, our data indicates $753 when flying from Knoxville to Chicago O'Hare Intl Airport.

  • Can I find deals for flights from Knoxville to O'Hare Intl that include hotel bookings?

    Yes. In addition to deals on Knoxville to O'Hare Intl flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to O'Hare Intl?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to O'Hare Intl.

  • Can I find deals for business class flights from Knoxville to O'Hare Intl?

    Yes. Cheapflights offers flight deals from Knoxville to O'Hare Intl by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Chicago O'Hare Intl Airport?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Chicago O'Hare Intl Airport (average of $216). Flying from Knoxville to Chicago O'Hare Intl Airport in October is currently the most expensive (average of $371). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago O'Hare Intl Airport?

Book flights to Chicago O'Hare Intl Airport if you plan to visit one of these locations
Rosemont
Schaumburg
Naperville
Gurnee
Lake Geneva
Delavan
Hoffman Estates
Downers Grove
Oakbrook Terrace
Benton Harbor
Des Plaines
Oak Brook
South Holland
Libertyville
Elgin
Warrenville
Elk Grove Village
Bridgeview
Great Lakes
Lansing

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Knoxville to O'Hare Intl

Discover the top 2 airlines that operate flights from Knoxville to O'Hare Intl. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$189Average$307FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$189Average$284FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights