HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
O'Hare Intl

$72+ Cheap flights from Knoxville (TYS) to O'Hare Intl (ORD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ORD
nov. 13 — nov. 201
jue. 11/13
jue. 11/20
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to O'Hare Intl with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Chicago O'Hare Intl are usually found in August or February, booked 38 days in advance, depart on a Friday or Thursday and return on a Wednesday

Cheap flight deals from Knoxville to O'Hare Intl

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to O'Hare Intl (ORD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated octubre 14, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$189
(American Airlines)

One-way from

$72
(Trip.com)

Popular in

October

Cheapest in

August

Average price

$363

Good round-trip deal

$336 or less

Good one-way deal

$218 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Chicago O'Hare Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Chicago O'Hare Intl flights.
Search Deals
From Knoxville McGhee Tyson to Chicago O'Hare Intl
Search Deals
One-way flight from Knoxville McGhee Tyson to Chicago O'Hare Intl
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals
Price to beat on a round-trip flight from Knoxville McGhee Tyson to Chicago O'Hare Intl.
Search Deals
Price to beat on a one-way flight from Knoxville McGhee Tyson to Chicago O'Hare Intl.
Search Deals

Find flight deals from Knoxville to O'Hare Intl

Cheapest flights from Knoxville to O'Hare Intl
Explore the most affordable flight options available from Knoxville to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 14, 2025.

This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/126:29 pmTYS - ORD
Nonstop2h 04mAmerican Airlines
dom. 12/143:08 pmORD - TYS
Nonstop1h 50mAmerican Airlines
Deal found 10/12$189
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/58:26 amTYS - ORD
Nonstop2h 04mUnited Airlines
dom. 11/97:20 amORD - TYS
Nonstop1h 45mUnited Airlines
Deal found 10/13$194
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/316:45 amTYS - ORD
Nonstop2h 01mUnited Airlines
lun. 11/35:50 pmORD - TYS
Nonstop1h 43mUnited Airlines
Deal found 10/14$199
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/117:59 pmTYS - ORD
1 stop5h 03mDelta
dom. 1/1812:15 pmORD - TYS
1 stop7h 21mDelta
Deal found 10/14$209
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/248:26 amTYS - ORD
Nonstop2h 04mUnited Airlines
vie. 11/2810:35 amORD - TYS
Nonstop1h 42mUnited Airlines
Deal found 10/13$212
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/610:50 amTYS - ORD
Nonstop2h 03mUnited Airlines
dom. 11/97:20 amORD - TYS
Nonstop1h 45mUnited Airlines
Deal found 10/13$213
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/307:48 amTYS - ORD
Nonstop2h 02mAmerican Airlines
jue. 1/16:33 pmORD - TYS
Nonstop1h 48mAmerican Airlines
Deal found 10/12$214
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/96:45 amTYS - ORD
Nonstop2h 01mUnited Airlines
dom. 11/165:50 pmORD - TYS
Nonstop1h 43mUnited Airlines
Deal found 10/12$217
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/112:58 pmTYS - ORD
Nonstop2h 08mAmerican Airlines
lun. 12/1511:42 amORD - TYS
Nonstop1h 45mAmerican Airlines
Deal found 10/14$219
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/248:50 amTYS - ORD
Nonstop2h 02mUnited Airlines
lun. 10/277:20 amORD - TYS
Nonstop1h 45mUnited Airlines
Deal found 10/13$224
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/66:30 amTYS - ORD
2 stops17h 58mMultiple Airlines
mié. 11/126:05 pmORD - TYS
1 stop23h 17mMultiple Airlines
Deal found 10/12$228

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to O'Hare Intl that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 14, 2025.
Use the filters below to find and compare flights from Knoxville to Chicago O'Hare Intl Airport that are best for you.

Fly from

Knoxville

Fly to

O'Hare Intl

Route

Depart

Return

Price

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

vie. 12/12

6:29 pm-7:33 pm

Nonstop2h 04m

Chicago O'Hare Intl

dom. 12/14

6:48 pm-9:40 pm

Nonstop1h 52m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

sáb. 11/8

8:26 am-9:30 am

Nonstop2h 04m

Chicago O'Hare Intl

sáb. 11/15

7:20 am-10:05 am

Nonstop1h 45m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

jue. 2/19

6:45 am-7:47 am

Nonstop2h 02m

Chicago O'Hare Intl

mar. 2/24

7:35 am-10:19 am

Nonstop1h 44m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

mar. 11/11

8:26 am-9:30 am

Nonstop2h 04m

Chicago O'Hare Intl

mar. 11/18

10:35 am-1:17 pm

Nonstop1h 42m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

jue. 12/11

7:59 pm-12:02 am

1 stop5h 03m

Chicago O'Hare Intl

lun. 12/15

2:30 pm-8:00 pm

1 stop4h 30m

$209

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

vie. 11/21

5:35 am-8:41 am

1 stop4h 06m

Chicago O'Hare Intl

vie. 11/28

5:13 pm-11:41 pm

1 stop5h 28m

$209

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

mié. 12/10

6:10 am-1:18 pm

1 stop8h 08m

Chicago O'Hare Intl

dom. 1/18

12:15 pm-8:36 pm

1 stop7h 21m

$209

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

jue. 12/11

7:59 pm-12:02 am

1 stop5h 03m

Chicago O'Hare Intl

dom. 1/18

12:15 pm-8:36 pm

1 stop7h 21m

$209

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

lun. 10/20

8:17 pm-9:09 pm

1 stop25h 52m

$113

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

jue. 12/11

6:30 am-6:34 pm

1 stop13h 04m

$117

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/13

Showing 1-10 of 17 results
1
2

Compare providers for flights from Knoxville to O'Hare Intl

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to O'Hare Intl in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Chicago O'Hare Intl Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Chicago O'Hare Intl Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Chicago O'Hare Intl Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Chicago O'Hare Intl Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Chicago O'Hare Intl Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to O'Hare Intl

Have a flexible travel schedule? Discover the best time to fly to O'Hare Intl from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Chicago O'Hare Intl Airport

How far ahead should I book a flight from Knoxville to Chicago O'Hare Intl Airport?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to O'Hare Intl. Price data was last updated on October 10, 2025.

To ensure you get the cheapest price possible for a flight from Knoxville to Chicago O'Hare Intl Airport, you should look to book at least 38 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Knoxville to Chicago O'Hare Intl Airport?

Currently, November is the cheapest month in which you can book a flight from Knoxville to Chicago O'Hare Intl Airport (average of $159). Flying from Knoxville to Chicago O'Hare Intl Airport in July is currently the most expensive (average of $194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to ORD?

Find hourly flight availability from Knoxville to O'Hare Intl. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 14, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 42% on flights from Knoxville to Chicago O'Hare Intl Airport by exploring options for tickets in the morning.

What is the cheapest day to fly from Knoxville to Chicago O'Hare Intl Airport?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to O'Hare Intl. Price data was last updated on October 12, 2025.

Travelers seeking maximum savings on their Knoxville to Chicago O'Hare Intl Airport flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing O'Hare Intl

Get insights into the airlines that provide service to O'Hare Intl. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to O'Hare Intl. Reviews last updated octubre 14, 2025.
Read reviews from past customers who have flown United Airlines and American Airlines from Knoxville to Chicago O'Hare Intl Airport. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,976 reviews

Boarding

7.7

Comfort

7.3

Overall

7.4

Crew

8.1

Entertainment

7.1

Food

6.6

Reviews

1 / 20
8.0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.
United Airlines
7.4
Good
8,976 reviews
United Airlines
7.4
Good
8,976 reviews

Boarding

7.7

Comfort

7.3

Overall

7.4

Crew

8.1

Entertainment

7.1

Food

6.6

Reviews

1 / 20
8.0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.
American Airlines
7.2
Good
11,042 reviews
United Airlines
7.4
Good
8,976 reviews

Boarding

7.7

Comfort

7.3

Overall

7.4

Crew

8.1

Entertainment

7.1

Food

6.6

Reviews

1 / 20
8.0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to O'Hare Intl. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Chicago O'Hare Intl?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson is the airport most travelers will use when flying to Chicago O'Hare Intl from Knoxville. Booking flights from McGhee Tyson (TYS) to Chicago O'Hare Intl should be relatively easy as there are 28 daily outbound flights to Chicago O'Hare Intl from 2 different airlines.

  • How long is the flight from Knoxville to Chicago O'Hare Intl Airport?

    A quick flight from Knoxville to Chicago O'Hare Intl Airport can take about 2h 04m. American Airlines provides one of the quickest options available for as low as $189. Airlines will cover a distance of 475 mi. Generally, flights for this route are nonstop.

  • What are the cheapest airlines flying from Knoxville to Chicago O'Hare Intl Airport round-trip?

    According to our current data, American Airlines ($189), and United Airlines ($192) offers the cheapest pricing from Knoxville to Chicago O'Hare Intl Airport. Users have found that American Airlines is 33% cheaper than the other options available to this destination.

  • What are the most reliable airlines from Knoxville to Chicago O'Hare Intl Airport?

    The top 3 most reliable airlines when flying from Knoxville to Chicago O'Hare Intl Airport are Republic Airways (95%), GoJet (93%) and Avianca (92%).

  • What are the cheapest flights from Knoxville to Chicago O'Hare Intl Airport?

    Looking at all options, your cheapest flight can be booked for $128. While the most popular route (Knoxville McGhee Tyson - Chicago O'Hare Intl) can be booked for $189 on average, our data indicates $922 when flying from Knoxville to Chicago O'Hare Intl Airport.

  • Can I find deals for flights from Knoxville to O'Hare Intl that include hotel bookings?

    Yes. In addition to deals on Knoxville to O'Hare Intl flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to O'Hare Intl?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to O'Hare Intl.

  • Can I find deals for business class flights from Knoxville to O'Hare Intl?

    Yes. Cheapflights offers flight deals from Knoxville to O'Hare Intl by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Chicago O'Hare Intl Airport?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Chicago O'Hare Intl Airport (average of $159). Flying from Knoxville to Chicago O'Hare Intl Airport in July is currently the most expensive (average of $194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago O'Hare Intl Airport?

Book flights to Chicago O'Hare Intl Airport if you plan to visit one of these locations
Schaumburg
Rosemont
Skokie
Des Plaines
Gurnee
Hoffman Estates
Elgin
Racine
Oak Brook
Elk Grove Village
Beloit
Rockford
Naperville
Downers Grove
Orland Park
Merrillville
Bridgeview
Warrenville
Joliet
Waukegan

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Knoxville to O'Hare Intl

Discover the top 2 airlines that operate flights from Knoxville to O'Hare Intl. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$189Average$269FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$192Average$315FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.