$119+ Cheap flights from Knoxville (TYS) to O'Hare Intl (ORD)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ORD
Oct 23 — Oct 301
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to O'Hare Intl with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Chicago O'Hare Intl are usually found in April or January, booked 66 days in advance, depart on a Friday or Thursday and return on a Saturday
Cheap flight deals from Knoxville to O'Hare Intl
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to O'Hare IntlExplore the most affordable flight options available from Knoxville to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
Explore the most affordable flight options available from Knoxville to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:15 am -
1 stop10h 15m
Mon 10/197:44 pm -
2 stops22h 08m
Deal found 9/18![Multiple Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:54 pm -
1 stop7h 45m
Mon 10/268:04 am -
1 stop10h 20m
Deal found 9/18![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:14 pm -
1 stop24h 16m
Wed 10/216:00 am -
2 stops28h 29m
Deal found 9/19![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:14 pm -
1 stop24h 16m
Wed 10/287:15 am -
2 stops27h 14m
Deal found 9/21![Multiple Airlines logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:17 pm -
1 stop10h 26m
Wed 11/117:15 am -
2 stops27h 23m
Deal found 9/20![Multiple Airlines logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:14 pm -
1 stop24h 23m
Sat 10/318:00 am -
1 stop24h 25m
Deal found 9/23![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:57 pm -
1 stop10h 42m
Fri 10/308:00 am -
1 stop25h 05m
Deal found 9/23![Multiple Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:55 pm -
1 stop28h 44m
Tue 10/138:04 am -
1 stop25h 01m
Deal found 9/18![Multiple Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:57 pm -
1 stop10h 42m
Mon 10/268:04 am -
1 stop10h 20m
Deal found 9/18![Multiple Airlines logo]()
$286
Best flights from Knoxville to O'Hare IntlDiscover carefully curated flight deals from Knoxville to O'Hare Intl that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
Discover carefully curated flight deals from Knoxville to O'Hare Intl that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
Nonstop1h 56m
Mon 10/196:03 pm -
Nonstop1h 46m
Deal found 9/18![United Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:38 pm -
1 stop7h 00m
Wed 10/215:27 am -
1 stop4h 27m
Deal found 9/19![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/710:51 am -
Nonstop2h 09m
Sun 11/86:55 am -
Nonstop1h 58m
Deal found 9/19![United Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:22 pm -
1 stop5h 32m
Sun 11/155:30 am -
1 stop4h 58m
Deal found 9/18![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:40 pm -
Nonstop2h 03m
Sun 11/155:59 pm -
Nonstop1h 55m
Deal found 9/23![United Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:42 am -
Nonstop1h 58m
Sun 10/255:59 pm -
Nonstop1h 55m
Deal found 9/21![United Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:10 am -
1 stop4h 29m
Sat 11/285:30 am -
1 stop4h 58m
Deal found 9/22![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:40 am -
1 stop5h 31m
Mon 10/126:30 am -
1 stop6h 10m
Deal found 9/23![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:45 am -
Nonstop2h 09m
Sat 11/282:07 pm -
Nonstop1h 52m
Deal found 9/23![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
Nonstop1h 56m
Mon 10/56:03 pm -
Nonstop1h 46m
Deal found 9/19![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:42 am -
Nonstop1h 58m
Sun 10/410:30 am -
Nonstop1h 44m
Deal found 9/19![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:45 am -
Nonstop2h 09m
Sun 11/296:55 am -
Nonstop1h 58m
Deal found 9/20![United Airlines logo]()
$370
Last-minute flights from Knoxville to O'Hare IntlDiscover last-minute flight deals from Knoxville to O'Hare Intl. Data last updated September 23, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to O'Hare Intl. Data last updated September 23, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:08 am -
1 stop6h 10m
Sun 10/44:50 pm -
Nonstop1h 53m
Deal found 9/19![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am -
Nonstop1h 56m
Sun 10/46:59 am -
Nonstop1h 46m
Deal found 9/22![United Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:08 am -
1 stop7h 20m
Mon 10/56:40 pm -
1 stop4h 15m
Deal found 9/22![American Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
Nonstop1h 56m
Sun 10/410:30 am -
Nonstop1h 44m
Deal found 9/18![United Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
Nonstop1h 56m
Mon 10/510:30 am -
Nonstop1h 44m
Deal found 9/21![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:42 am -
Nonstop1h 58m
Tue 10/68:50 am -
1 stop4h 52m
Deal found 9/21![United Airlines logo]()
$414
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:14 pm -
Nonstop2h 15m
Tue 10/68:20 am -
Nonstop1h 45m
Deal found 9/19![American Airlines logo]()
$391
One-way flights from Knoxville to O'Hare IntlSearch for one-way flight options from Knoxville to O'Hare Intl. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
Search for one-way flight options from Knoxville to O'Hare Intl. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:04 pm -
1 stop21h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:15 am -
1 stop10h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2112:21 pm -
1 stop7h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:14 pm -
1 stop24h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:54 pm -
1 stop7h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:21 pm -
1 stop9h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:52 pm -
1 stop17h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1612:25 pm -
1 stop25h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:57 pm -
1 stop10h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/129:33 pm -
1 stop18h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$134
Find flight deals from Knoxville to O'Hare Intl
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to O'Hare Intl (ORD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $265 (Kiwi.com) |
One-way from | $119 (Kiwi.com) |
Popular in | June |
Cheapest in | April |
Average price | $349 |
Good round-trip deal | $368 or less |
Good one-way deal | $265 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to O'Hare Intl that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
Use the filters below to find and compare flights from Knoxville to Chicago O'Hare Intl Airport that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleChicago
TYS Knoxville McGhee Tyson - ORD Chicago O'Hare Intl
TYSORD
Knoxville McGhee Tyson
Tue 10/20
7:04 pm-6:31 pm
3 stops24h 27m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$195
KnoxvilleChicago
TYS Knoxville McGhee Tyson - ORD Chicago O'Hare Intl
TYSORD
Knoxville McGhee Tyson
Mon 10/26
6:45 am-7:54 am
Nonstop2h 09m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$214
KnoxvilleChicago
TYS Knoxville McGhee Tyson - ORD Chicago O'Hare Intl
TYSORD
Knoxville McGhee Tyson
Sat 10/17
4:11 pm-8:38 pm
1 stop5h 27m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$224
KnoxvilleChicago
TYS Knoxville McGhee Tyson - ORD Chicago O'Hare Intl
TYSORD
Knoxville McGhee Tyson
Tue 10/6
10:42 am-11:40 am
Nonstop1h 58m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$234
KnoxvilleChicago
TYS Knoxville McGhee Tyson - ORD Chicago O'Hare Intl
TYSORD
Knoxville McGhee Tyson
Sun 10/11
10:42 am-11:40 am
Nonstop1h 58m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$244
KnoxvilleChicago
TYS Knoxville McGhee Tyson - ORD Chicago O'Hare Intl
TYSORD
Knoxville McGhee Tyson
Sat 11/21
1:56 pm-3:00 pm
Nonstop2h 04m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$259
KnoxvilleChicago
TYS Knoxville McGhee Tyson - ORD Chicago O'Hare Intl
TYSORD
Knoxville McGhee Tyson
Fri 12/18
6:30 am-7:41 am
Nonstop2h 11m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$259
Quickest round-trip
KnoxvilleChicago
TYS Knoxville McGhee Tyson - ORD Chicago O'Hare Intl
TYSORD
Knoxville McGhee Tyson
Sat 10/17
6:00 am-6:56 am
Nonstop1h 56m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$259
KnoxvilleChicago
TYS Knoxville McGhee Tyson - ORD Chicago O'Hare Intl
TYSORD
Knoxville McGhee Tyson
Thu 11/19
1:51 pm-2:55 pm
Nonstop2h 04m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$259
KnoxvilleChicago
TYS Knoxville McGhee Tyson - ORD Chicago O'Hare Intl
TYSORD
Knoxville McGhee Tyson
Tue 11/24
6:45 am-7:54 am
Nonstop2h 09m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$259
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Knoxville to O'Hare Intl
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to O'Hare Intl in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Chicago O'Hare Intl Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Chicago O'Hare Intl Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Chicago O'Hare Intl Airport flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Chicago O'Hare Intl Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Chicago O'Hare Intl Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to O'Hare Intl
Have a flexible travel schedule? Discover the best time to fly to O'Hare Intl from Knoxville with our price prediction graph.
TYS-ORD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Chicago O'Hare Intl Airport
Prices
Airlines
How far ahead should I book a flight from Knoxville to Chicago O'Hare Intl Airport?
To ensure you get the cheapest price possible for a flight from Knoxville to Chicago O'Hare Intl Airport, you should look to book at least 32 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Knoxville to Chicago O'Hare Intl Airport?
Currently, April is the cheapest month in which you can book a flight from Knoxville to Chicago O'Hare Intl Airport (average of $264). Flying from Knoxville to Chicago O'Hare Intl Airport in June is currently the most expensive (average of $404). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TYS to ORD?
Find hourly flight availability from Knoxville to O'Hare Intl. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 23, 2026.
Unlike at noon, when flights are generally more expensive, you can save up to 40% on flights from Knoxville to Chicago O'Hare Intl Airport by exploring options for tickets in the morning.
What is the cheapest day to fly from Knoxville to Chicago O'Hare Intl Airport?
Use this chart to determine the cheapest time to fly round-trip from Knoxville to O'Hare Intl. Price data was last updated on September 19, 2026.
Travelers seeking maximum savings on their Knoxville to Chicago O'Hare Intl Airport flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing O'Hare Intl
Get insights into the airlines that provide service to O'Hare Intl. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to O'Hare Intl. Reviews last updated September 23, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Knoxville to Chicago O'Hare Intl Airport. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Entertainment
7.1
Boarding
7.7
Food
6.7
Comfort
7.3
Overall
7.4
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Crew
8.1
Entertainment
7.1
Boarding
7.7
Food
6.7
Comfort
7.3
Overall
7.4
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Crew
8.1
Entertainment
7.1
Boarding
7.7
Food
6.7
Comfort
7.3
Overall
7.4
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Knoxville to O'Hare Intl. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago O'Hare Intl Airport?
Book flights to Chicago O'Hare Intl Airport if you plan to visit one of these locationsBenton Harbor
Rosemont
Des Plaines
Lake Geneva
Naperville
Glenview
Schaumburg
Oakbrook Terrace
Delavan
Oak Brook
Aurora
Libertyville
Rockford
Hoffman Estates
Beloit
Orland Park
South Holland
Elgin
Racine
Janesville
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Top 2 airlines flying from Knoxville to O'Hare Intl
Discover the top 2 airlines that operate flights from Knoxville to O'Hare Intl. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$189 | Average$326 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$189 | Average$317 | FlexibilityNo cancel fee | On-time71% |