HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
O'Hare Intl

$91+ Cheap flights from Knoxville (TYS) to O'Hare Intl (ORD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ORD
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to O'Hare Intl with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Chicago O'Hare Intl are usually found in August or February, booked 38 days in advance, depart on a Friday or Thursday and return on a Wednesday

Cheap flight deals from Knoxville to O'Hare Intl

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to O'Hare Intl (ORD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 20, 2025.

Round-trip from

$179
(FlightHub)

One-way from

$91
(FlightHub)

Popular in

January

Cheapest in

August

Average price

$204

Good round-trip deal

$306 or less

Good one-way deal

$278 or less
From Knoxville McGhee Tyson to Chicago O'Hare Intl
Search Deals
One-way flight from Knoxville McGhee Tyson to Chicago O'Hare Intl
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($26 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
Search Deals
Price to beat on a round-trip flight from Knoxville McGhee Tyson to Chicago O'Hare Intl.
Search Deals
Price to beat on a one-way flight from Knoxville McGhee Tyson to Chicago O'Hare Intl.
Search Deals

Find flight deals from Knoxville to O'Hare Intl

Cheapest flights from Knoxville to O'Hare Intl
Explore the most affordable flight options available from Knoxville to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/48:40 pmTYS - ORD
1 stop13h 57mFrontier
Sun 9/76:00 amORD - TYS
1 stop9h 18mFrontier
Deal found 8/18$179
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/122:00 pmTYS - ORD
Nonstop2h 02mUnited Airlines
Sun 9/147:55 pmORD - TYS
Nonstop1h 50mUnited Airlines
Deal found 8/18$189
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/57:00 amTYS - ORD
Nonstop1h 55mUnited Airlines
Fri 9/127:45 pmORD - TYS
Nonstop1h 51mUnited Airlines
Deal found 8/18$194
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/44:48 pmTYS - ORD
Nonstop2h 01mAmerican Airlines
Mon 9/89:28 amORD - TYS
Nonstop1h 53mAmerican Airlines
Deal found 8/19$199
This FlightHub deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/48:40 pmTYS - ORD
1 stop13h 57mFrontier
Mon 9/810:42 amORD - TYS
1 stop8h 03mFrontier
Deal found 8/19$205
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:11 pmTYS - ORD
1 stop5h 43mDelta
Mon 9/297:10 amORD - TYS
1 stop3h 31mDelta
Deal found 8/18$209
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/188:30 amTYS - ORD
1 stop12h 14mMultiple Airlines
Thu 9/258:05 amORD - TYS
1 stop11h 26mMultiple Airlines
Deal found 8/19$211
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/55:19 pmTYS - ORD
1 stop6h 01mDelta
Mon 9/85:45 amORD - TYS
1 stop3h 57mDelta
Deal found 8/18$214
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/147:00 amTYS - ORD
1 stop27h 37mMultiple Airlines
Sun 9/218:49 pmORD - TYS
1 stop24h 45mMultiple Airlines
Deal found 8/19$217
This Frontier deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/75:08 pmTYS - ORD
1 stop7h 51mFrontier
Mon 9/810:42 amORD - TYS
1 stop8h 03mFrontier
Deal found 8/18$218
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/263:13 pmTYS - ORD
Nonstop2h 08mAmerican Airlines
Sun 9/2811:56 amORD - TYS
Nonstop1h 47mAmerican Airlines
Deal found 8/18$219
This Mytrip deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/104:31 pmTYS - ORD
1 stop7h 17mMultiple Airlines
Fri 9/125:46 pmORD - TYS
1 stop15h 21mMultiple Airlines
Deal found 8/18$220

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to O'Hare Intl that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Knoxville to Chicago O'Hare Intl Airport that are best for you.

Fly from

Knoxville

Fly to

O'Hare Intl

Route

Depart

Return

Price

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 9/4

8:40 pm-9:37 am

1 stop13h 57m

Chicago O'Hare Intl

Sun 9/7

6:00 am-4:18 pm

1 stop9h 18m

$179

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Tue 10/14

5:37 pm-6:33 pm

Nonstop1h 56m

Chicago O'Hare Intl

Sat 12/13

8:00 am-10:42 am

Nonstop1h 42m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Tue 9/9

5:35 pm-6:37 pm

Nonstop2h 02m

Chicago O'Hare Intl

Sat 9/13

7:17 am-9:58 am

Nonstop1h 41m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 9/12

7:14 am-8:18 am

Nonstop2h 04m

Chicago O'Hare Intl

Mon 9/15

11:56 am-2:43 pm

Nonstop1h 47m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 9/12

2:00 pm-3:02 pm

Nonstop2h 02m

Chicago O'Hare Intl

Sun 9/14

7:55 pm-10:45 pm

Nonstop1h 50m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 9/12

7:14 am-8:18 am

Nonstop2h 04m

Chicago O'Hare Intl

Mon 9/22

1:37 pm-4:19 pm

Nonstop1h 42m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 9/25

12:51 pm-1:49 pm

Nonstop1h 58m

Chicago O'Hare Intl

Sun 9/28

11:56 am-2:43 pm

Nonstop1h 47m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 11/14

5:52 pm-6:56 pm

Nonstop2h 04m

Chicago O'Hare Intl

Sun 11/16

11:43 am-2:29 pm

Nonstop1h 46m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 9/17

7:14 am-8:18 am

Nonstop2h 04m

Chicago O'Hare Intl

Sun 9/21

9:28 am-12:21 pm

Nonstop1h 53m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Mon 9/15

8:35 pm-9:28 pm

1 stop25h 53m

$91

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/18

Showing 1-10 of 17 results
1
2

Best time to book a flight from Knoxville to O'Hare Intl

Have a flexible travel schedule? Discover the best time to fly to O'Hare Intl from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Chicago O'Hare Intl Airport

How far ahead should I book a flight from Knoxville to Chicago O'Hare Intl Airport?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to O'Hare Intl. Price data was last updated on August 8, 2025.

To ensure you get the cheapest price possible for a flight from Knoxville to Chicago O'Hare Intl Airport, you should look to book at least 38 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Knoxville to Chicago O'Hare Intl Airport?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Chicago O'Hare Intl Airport (average of $245). Flying from Knoxville to Chicago O'Hare Intl Airport in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to ORD?

Find hourly flight availability from Knoxville to O'Hare Intl. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 43% on flights from Knoxville to Chicago O'Hare Intl Airport by exploring options for tickets in the morning.

What is the cheapest day to fly from Knoxville to Chicago O'Hare Intl Airport?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to O'Hare Intl. Price data was last updated on August 17, 2025.

Travelers seeking maximum savings on their Knoxville to Chicago O'Hare Intl Airport flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing O'Hare Intl

Get insights into the airlines that provide service to O'Hare Intl. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to O'Hare Intl. Reviews last updated August 20, 2025.
Read reviews from past customers who have flown United Airlines and American Airlines from Knoxville to Chicago O'Hare Intl Airport. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,928 reviews

Comfort

7.3

Overall

7.4

Boarding

7.7

Crew

8.1

Food

6.6

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,928 reviews
United Airlines
7.4
Good
8,928 reviews

Comfort

7.3

Overall

7.4

Boarding

7.7

Crew

8.1

Food

6.6

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,928 reviews

Comfort

7.3

Overall

7.4

Boarding

7.7

Crew

8.1

Food

6.6

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to O'Hare Intl. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Chicago O'Hare Intl?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson is the airport most travelers will use when flying to Chicago O'Hare Intl from Knoxville. Booking flights from McGhee Tyson (TYS) to Chicago O'Hare Intl should be relatively easy as there are 30 daily outbound flights to Chicago O'Hare Intl from 2 different airlines.

  • How long is the flight from Knoxville to Chicago O'Hare Intl Airport?

    A quick flight from Knoxville to Chicago O'Hare Intl Airport can take about 1h 56m. Frontier provides one of the quickest options available for as low as $189. Airlines will cover a distance of 475 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Knoxville to Chicago O'Hare Intl Airport round-trip?

    According to our current data, American Airlines ($179), and United Airlines ($189) offers the cheapest pricing from Knoxville to Chicago O'Hare Intl Airport. Users have found that American Airlines is 34% cheaper than the other options available to this destination.

  • What are the most reliable airlines from Knoxville to Chicago O'Hare Intl Airport?

    The top 3 most reliable airlines when flying from Knoxville to Chicago O'Hare Intl Airport are Avianca (93%), Envoy Air (89%) and Republic Airways (86%).

  • What are the cheapest flights from Knoxville to Chicago O'Hare Intl Airport?

    Looking at all options, your cheapest flight can be booked for $180. While the most popular route (Knoxville McGhee Tyson - Chicago O'Hare Intl) can be booked for $189 on average our data indicates $1,137 when flying from Knoxville to Chicago O'Hare Intl Airport.

  • Can I find deals for flights from Knoxville to O'Hare Intl that include hotel bookings?

    Yes. In addition to deals on Knoxville to O'Hare Intl flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to O'Hare Intl?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to O'Hare Intl.

  • Can I find deals for business class flights from Knoxville to O'Hare Intl?

    Yes. Cheapflights offers flight deals from Knoxville to O'Hare Intl by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Chicago O'Hare Intl Airport?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Chicago O'Hare Intl Airport (average of $245). Flying from Knoxville to Chicago O'Hare Intl Airport in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago O'Hare Intl Airport?

Book flights to Chicago O'Hare Intl Airport if you plan to visit one of these locations
Schaumburg
Rosemont
Hoffman Estates
Beloit
Skokie
Des Plaines
Elgin
Gurnee
Arlington Heights
Racine
Rockford
Great Lakes
Orland Park
Naperville
Merrillville
Elk Grove Village
Downers Grove
Evanston
Lake Geneva
Joliet

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Knoxville to O'Hare Intl

Discover the top 2 airlines that operate flights from Knoxville to O'Hare Intl. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$179Average$257FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$189Average$303FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.