
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $210 (Kiwi.com) |
One-way from | $66 (Kiwi.com) |
Popular in | March |
Cheapest in | January |
Average price | $249 |
Good round-trip deal | $120 or less |
Good one-way deal | $80 or less |
Fly from
Fly to
Route
Depart
Return
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Tue 6/23
6:55 pm-9:10 pm
1 stop3h 15m
Chicago Midway
Tue 6/30
9:00 am-5:00 pm
1 stop7h 00m
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Wed 5/27
12:50 pm-5:30 pm
1 stop5h 40m
Chicago Midway
Wed 6/3
1:00 pm-8:50 pm
1 stop6h 50m
KnoxvilleChicago
TYS - ORD
TYSORD
Knoxville McGhee Tyson
Thu 5/21
6:30 am-7:29 am
Nonstop1h 59m
Chicago O'Hare Intl
Tue 5/26
7:10 am-10:05 am
Nonstop1h 55m
KnoxvilleSt. Louis
TYS - STL
TYSSTL
Knoxville McGhee Tyson
Tue 5/26
5:50 pm-10:00 pm
1 stop5h 10m
Lambert-St Louis
Sat 5/30
6:20 am-1:20 pm
1 stop6h 00m
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Fri 5/29
5:59 pm-9:09 pm
1 stop4h 10m
Chicago Midway
Tue 6/2
6:23 am-1:10 pm
1 stop5h 47m
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Sat 8/8
7:11 am-12:33 pm
1 stop6h 22m
Chicago Midway
Sat 8/15
10:35 am-3:07 pm
1 stop3h 32m
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Thu 10/22
4:00 pm-9:45 pm
1 stop6h 45m
Chicago Midway
Mon 10/26
5:25 pm-11:46 pm
1 stop5h 21m
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Sat 5/23
5:40 pm-10:35 pm
1 stop5h 55m
Chicago Midway
Sat 5/30
2:15 pm-6:30 pm
1 stop3h 15m
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Sat 5/23
5:35 pm-9:09 pm
1 stop4h 34m
Chicago Midway
Mon 5/25
6:23 am-11:09 am
1 stop3h 46m
KnoxvilleChicago
TYS - MDW
TYSMDW
Knoxville McGhee Tyson
Thu 5/21
5:40 am-10:00 am
1 stop5h 20m
Chicago Midway
Sun 5/24
6:23 am-11:09 am
1 stop3h 46m
To ensure you get the cheapest price possible for a flight from Knoxville to Illinois, you should look to book at least 70 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Currently, November is the cheapest month in which you can book a flight from Knoxville to Illinois (average of $48). Flying from Knoxville to Illinois in March is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
It’s typically best to fly out from Knoxville to Illinois in the morning. Doing so could potentially save you 25% on the flight price compared to flying in the evening, which is usually more expensive.
Travelers seeking maximum savings on their Knoxville to Illinois flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
The most flights from TYS to USIL are scheduled on a Friday (33 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (21 on average).
Overall
Comfort
Food
Crew
Boarding
Entertainment
Reviews
Dane,Jan 2026
TYS - IAD
Overall
Comfort
Food
Crew
Boarding
Entertainment
Reviews
Dane,Jan 2026
TYS - IAD
Overall
Comfort
Food
Crew
Boarding
Entertainment
Reviews
Dane,Jan 2026
TYS - IAD
Overall
Comfort
Food
Crew
Boarding
Entertainment
Reviews
Dane,Jan 2026
TYS - IAD
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$60 | Average$103 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$189 | Average$342 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$189 | Average$307 | FlexibilityNo cancel fee | On-time71% |