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Charleston

$158+ Cheap flights from Iowa to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CHS
Mar 7 — Mar 141
Sat 3/7
Sat 3/14
1 adult, Economy
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Cheap flight deals from Iowa to Charleston

Cheapest flights from Iowa to Charleston
Explore the most affordable flight options available from Iowa to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.

This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:15 am
MLI
-
CHS
1 stop4h 37m
United Airlines
Mon 3/96:45 pm
CHS
-
MLI
1 stop4h 37m
United Airlines
Deal found 2/3$269
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/284:48 pm
CID
-
CHS
1 stop5h 13m
American Airlines
Mon 3/28:25 pm
CHS
-
CID
1 stop4h 34m
American Airlines
Deal found 2/2$269
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:45 am
CID
-
CHS
1 stop4h 39m
Delta
Tue 6/304:30 pm
CHS
-
CID
1 stop6h 20m
Delta
Deal found 2/2$276
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/175:32 am
CID
-
CHS
1 stop6h 49m
Delta
Wed 3/255:27 am
CHS
-
CID
2 stops6h 44m
Delta
Deal found 2/3$288
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:20 pm
MLI
-
CHS
1 stop7h 07m
United Airlines
Sun 4/126:00 am
CHS
-
MLI
1 stop4h 58m
United Airlines
Deal found 2/1$300
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/283:52 pm
MLI
-
CHS
2 stops7h 07m
United Airlines
Tue 4/78:00 am
CHS
-
MLI
1 stop5h 27m
United Airlines
Deal found 2/5$304
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/241:01 pm
CID
-
CHS
1 stop5h 11m
American Airlines
Tue 6/308:25 am
CHS
-
CID
1 stop5h 56m
American Airlines
Deal found 2/4$304
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:07 am
OMA
-
CHS
1 stop22h 28m
Multiple Airlines
Thu 3/59:36 pm
CHS
-
OMA
2 stops23h 42m
Multiple Airlines
Deal found 2/4$310
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:29 pm
DSM
-
CHS
2 stops20h 11m
Multiple Airlines
Thu 3/53:01 pm
CHS
-
DSM
1 stop19h 35m
Multiple Airlines
Deal found 2/4$313
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:45 pm
CID
-
CHS
1 stop26h 56m
Multiple Airlines
Mon 4/207:00 am
CHS
-
CID
1 stop11h 55m
Multiple Airlines
Deal found 2/2$318
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:00 pm
MLI
-
CHS
1 stop5h 57m
Delta
Sun 9/136:30 am
CHS
-
MLI
1 stop4h 56m
Delta
Deal found 2/2$319
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:33 am
CID
-
CHS
1 stop6h 19m
United Airlines
Wed 3/188:15 am
CHS
-
CID
1 stop5h 00m
United Airlines
Deal found 2/2$319

Find flight deals from Iowa to Charleston

Keep the following information in mind while searching for Iowa to Charleston flight deals. Data was last updated February 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$264
(Kiwi.com)

One-way from

$158
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$421
Provider with most accurate pricing for Des Moines-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Charleston flights.
Search Deals
From Iowa to Charleston
Search Deals
One-way flight from Iowa to Charleston
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($94 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Iowa to Charleston that are best for you.

Fly from

Iowa

Fly to

Charleston

Route

Depart

Return

Price

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Wed 4/29

2:00 pm-9:25 pm

1 stop6h 25m

Charleston

Sat 5/2

6:48 pm-10:45 pm

1 stop4h 57m

$269

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Thu 7/9

5:00 pm-11:57 pm

1 stop5h 57m

Charleston

Sun 7/12

5:30 am-10:26 am

1 stop5h 56m

$269

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Wed 3/4

8:15 am-1:52 pm

1 stop4h 37m

Charleston

Mon 3/9

6:45 pm-10:22 pm

1 stop4h 37m

$269

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Sat 7/4

11:28 am-5:45 pm

1 stop5h 17m

Charleston

Tue 7/7

3:19 pm-9:34 pm

1 stop7h 15m

$269

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Sat 2/28

1:15 pm-11:01 pm

2 stops8h 46m

Charleston

Mon 3/2

7:03 pm-11:59 pm

1 stop5h 56m

$274

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Mon 3/9

5:32 am-1:21 pm

1 stop6h 49m

Charleston

Wed 3/18

5:27 am-11:11 am

2 stops6h 44m

$274

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Wed 6/24

5:45 am-11:24 am

1 stop4h 39m

Charleston

Tue 6/30

4:30 pm-9:50 pm

1 stop6h 20m

$276

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Thu 4/9

3:20 pm-11:27 pm

1 stop7h 07m

Charleston

Sun 4/12

6:00 am-9:58 am

1 stop4h 58m

$300

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Wed 6/24

7:31 am-2:47 pm

1 stop6h 16m

Charleston

Tue 6/30

5:05 am-12:31 pm

2 stops8h 26m

$309

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Mon 3/9

6:33 am-1:52 pm

1 stop6h 19m

Charleston

Wed 3/18

8:15 am-12:15 pm

1 stop5h 00m

$319

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/3

Showing 1-10 of 51 results
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Best time to book a flight from Iowa to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Charleston

What is the cheapest month to book a flight from Iowa to Charleston?

Currently, May is the cheapest month in which you can book a flight from Iowa to Charleston (average of $166). Flying from Iowa to Charleston in March is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Charleston from Iowa?

    If you book a flight to Charleston from Iowa, you will be flying to Charleston, which is the city’s only airport. Charleston (CHS) is located 10.2 mi from the center of Charleston.

  • How long is the flight from Iowa to Charleston?

    Airlines like United Airlines, Delta, and American Airlines fly from Iowa to Charleston in about 5h 57m. The time it takes to get you to your destination can typically vary by up to 2h 49m. Airlines will cover a distance of 824 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Iowa to Charleston?

    The most popular route from Iowa to Charleston is Omaha Eppley Airfield - Charleston. You may also consider Cedar Rapids - Charleston or Des Moines - Charleston.

  • Can I find deals for flights from Iowa to Charleston that include hotel bookings?

    Yes. In addition to deals on Iowa to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Charleston.

  • Can I find deals for business class flights from Iowa to Charleston?

    Yes. Cheapflights offers flight deals from Iowa to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Charleston?

    Currently, May is the cheapest month in which you can book a flight from Iowa to Charleston (average of $166). Flying from Iowa to Charleston in March is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Iowa to Charleston

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Iowa to Charleston

Discover the top 3 airlines that operate flights from Iowa to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$166Average$324FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$229Average$365FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$390FlexibilityNo cancel feeOn-time69%

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