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Charleston

$165+ Cheap flights from Iowa to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CHS
ene. 15 — ene. 221
jue. 1/15
jue. 1/22
1 adult, Economy
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Cheap flight deals from Iowa to Charleston

Cheapest flights from Iowa to Charleston
Explore the most affordable flight options available from Iowa to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.

This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/313:27 pmCID - CHS
1 stop7h 30mAmerican Airlines
dom. 1/44:49 pmCHS - CID
1 stop6h 48mAmerican Airlines
Deal found 12/16$279
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/241:58 pmOMA - CHS
1 stop4h 34mAmerican Airlines
jue. 1/18:08 pmCHS - OMA
1 stop4h 51mAmerican Airlines
Deal found 12/16$301
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/241:58 pmOMA - CHS
1 stop4h 34mAmerican Airlines
mié. 1/1412:37 pmCHS - OMA
1 stop6h 04mAmerican Airlines
Deal found 12/15$327
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/312:07 pmDSM - CHS
1 stop4h 41mAmerican Airlines
dom. 1/48:08 pmCHS - DSM
1 stop5h 29mAmerican Airlines
Deal found 12/14$338
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/248:31 amDSM - CHS
2 stops35h 52mMultiple Airlines
mar. 12/302:15 pmCHS - DSM
1 stop24h 39mMultiple Airlines
Deal found 12/14$369
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/313:44 pmOMA - CHS
1 stop5h 42mAmerican Airlines
dom. 1/48:08 pmCHS - OMA
1 stop4h 51mAmerican Airlines
Deal found 12/15$384
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/311:09 pmDSM - CHS
1 stop8h 17mAmerican Airlines
vie. 1/28:08 pmCHS - DSM
1 stop5h 29mAmerican Airlines
Deal found 12/14$403
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/248:47 amDSM - CHS
2 stops9h 45mAmerican Airlines
mar. 12/305:10 amCHS - DSM
2 stops8h 53mAmerican Airlines
Deal found 12/14$433
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/302:07 pmDSM - CHS
1 stop4h 21mAmerican Airlines
vie. 1/95:57 pmCHS - DSM
1 stop6h 26mAmerican Airlines
Deal found 12/14$437
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/302:07 pmDSM - CHS
1 stop4h 21mAmerican Airlines
lun. 1/54:13 pmCHS - DSM
2 stops8h 17mAmerican Airlines
Deal found 12/14$442
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/157:34 pmOMA - CHS
1 stop12h 03mMultiple Airlines
dom. 12/212:59 pmCHS - OMA
1 stop26h 50mMultiple Airlines
Deal found 12/14$460
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/216:42 pmOMA - CHS
2 stops51h 01mMultiple Airlines
dom. 1/118:59 pmCHS - OMA
1 stop14h 21mMultiple Airlines
Deal found 12/15$463

Find flight deals from Iowa to Charleston

Keep the following information in mind while searching for Iowa to Charleston flight deals. Data was last updated diciembre 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$243
(Delta)

One-way from

$165
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$426
Provider with most accurate pricing for Des Moines-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Charleston flights.
Search Deals
From Iowa to Charleston
Search Deals
One-way flight from Iowa to Charleston
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($90 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 16, 2025.
Use the filters below to find and compare flights from Iowa to Charleston that are best for you.

Fly from

Iowa

Fly to

Charleston

Route

Depart

Return

Price

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

vie. 1/16

5:11 pm-11:55 pm

1 stop5h 44m

Charleston

dom. 1/18

5:18 pm-10:33 pm

1 stop6h 15m

$243

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

dom. 1/11

2:58 pm-5:36 pm

1 stop25h 38m

Charleston

dom. 1/18

11:10 am-7:23 pm

2 stops33h 13m

$246

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

vie. 1/9

8:00 am-2:02 pm

1 stop5h 02m

Charleston

lun. 1/12

4:41 pm-9:34 pm

1 stop5h 53m

$269

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

jue. 1/29

5:35 am-11:48 am

1 stop5h 13m

Charleston

lun. 2/2

3:28 pm-9:47 pm

1 stop7h 19m

$269

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

mié. 12/31

3:27 pm-11:57 pm

1 stop7h 30m

Charleston

dom. 1/4

4:49 pm-10:37 pm

1 stop6h 48m

$279

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

jue. 2/5

6:35 am-2:48 pm

2 stops7h 13m

Charleston

lun. 2/9

2:58 pm-9:34 pm

2 stops7h 36m

$279

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

vie. 1/16

11:28 am-9:11 pm

2 stops8h 43m

Charleston

dom. 1/18

3:16 pm-9:58 pm

1 stop7h 42m

$283

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

jue. 1/29

2:58 pm-5:36 pm

1 stop25h 38m

Charleston

jue. 2/5

6:35 pm-10:19 am

2 stops16h 44m

$285

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

dom. 1/18

10:14 am-6:19 pm

1 stop7h 05m

Charleston

sáb. 1/24

9:00 am-12:15 pm

1 stop4h 15m

$293

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

dom. 1/18

1:55 pm-11:07 pm

2 stops8h 12m

Charleston

sáb. 1/24

7:42 pm-11:42 pm

1 stop5h 00m

$298

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 43 results
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Best time to book a flight from Iowa to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Charleston

What is the cheapest month to book a flight from Iowa to Charleston?

Currently, May is the cheapest month in which you can book a flight from Iowa to Charleston (average of $166). Flying from Iowa to Charleston in March is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to CHS?

Find hourly flight availability from Iowa to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 16, 2025.

One of the essential ways to save on airfare from Iowa to Charleston is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 35% on airfare.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Charleston from Iowa?

    If you book a flight to Charleston from Iowa, you will be flying to Charleston, which is the city’s only airport. Charleston (CHS) is located 10.2 mi from the center of Charleston.

  • How long is the flight from Iowa to Charleston?

    Airlines like Delta, United Airlines, and American Airlines fly from Iowa to Charleston in about 5h 02m. The time it takes to get you to your destination can typically vary by up to 2h 28m. Airlines will cover a distance of 890 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Iowa to Charleston?

    The most popular route from Iowa to Charleston is Omaha Eppley Airfield - Charleston. You may also consider Des Moines - Charleston or Moline Quad-City - Charleston.

  • Can I find deals for flights from Iowa to Charleston that include hotel bookings?

    Yes. In addition to deals on Iowa to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Charleston.

  • Can I find deals for business class flights from Iowa to Charleston?

    Yes. Cheapflights offers flight deals from Iowa to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Charleston?

    Currently, May is the cheapest month in which you can book a flight from Iowa to Charleston (average of $166). Flying from Iowa to Charleston in March is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach

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Alternative routes for Iowa to Charleston

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Iowa to Charleston

Discover the top 3 airlines that operate flights from Iowa to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$199Average$335FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$229Average$366FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$378FlexibilityNo cancel feeOn-time69%

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