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Central America

$146+ Cheap flights from Des Moines (DSM) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SJO
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Des Moines to Central America

Keep the following information in mind while searching for Des Moines to Central America flight deals. Data was last updated July 29, 2025.

Round-trip from

$299
(American Airlines)

One-way from

$146
(Avianca)

Popular in

December

Cheapest in

September

Average price

$664
From Des Moines to Central America
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One-way flight from Des Moines to Central America
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Highest demand for flights based on searches. 22% potential increase in price ($215 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($66 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Des Moines to Central America

Cheapest flights from Des Moines to Central America
Explore the most affordable flight options available from Des Moines to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/125:38 pmDSM - SJO
1 stop20h 07mAmerican Airlines
Fri 9/197:27 amSJO - DSM
1 stop24h 37mAmerican Airlines
Deal found 7/28$299
This Avianca deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/166:02 amDSM - SAL
1 stop10h 58mMultiple Airlines
Wed 8/278:00 amSAL - DSM
1 stop13h 28mMultiple Airlines
Deal found 7/27$365
This Mytrip deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/205:51 pmDSM - GUA
2 stops18h 34mMultiple Airlines
Thu 10/2312:20 pmGUA - DSM
3 stops27h 39mMultiple Airlines
Deal found 7/28$384
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/113:18 pmDSM - BZE
2 stops20h 50mAmerican Airlines
Tue 11/184:21 pmBZE - DSM
2 stops19h 44mAmerican Airlines
Deal found 7/29$408
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/126:15 amDSM - PTY
1 stop12h 22mUnited Airlines
Mon 10/2010:00 amPTY - DSM
1 stop12h 28mUnited Airlines
Deal found 7/28$461
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/124:09 pmDSM - PTY
2 stops22h 22mAmerican Airlines
Fri 9/193:31 pmPTY - DSM
2 stops23h 45mAmerican Airlines
Deal found 7/29$465
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:44 amDSM - GUA
1 stop6h 46mDelta
Mon 10/612:56 pmGUA - DSM
1 stop8h 47mDelta
Deal found 7/29$466
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/126:39 pmDSM - PTY
1 stop18h 17mDelta
Fri 10/172:21 pmPTY - DSM
2 stops26h 31mDelta
Deal found 7/28$466
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/166:02 amDSM - SAL
1 stop15h 15mUnited Airlines
Wed 8/271:25 pmSAL - DSM
2 stops21h 58mUnited Airlines
Deal found 7/27$471
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:00 pmDSM - SAL
2 stops18h 20mAmerican Airlines
Sat 11/152:29 pmSAL - DSM
1 stop8h 30mAmerican Airlines
Deal found 7/27$476
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:11 pmDSM - GUA
2 stops18h 15mAmerican Airlines
Mon 10/612:37 pmGUA - DSM
2 stops9h 46mAmerican Airlines
Deal found 7/29$487
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/196:22 pmDSM - MGA
2 stops19h 43mAmerican Airlines
Tue 10/282:05 pmMGA - DSM
2 stops23h 58mAmerican Airlines
Deal found 7/29$493

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Des Moines to Central America that are best for you.

Fly from

Des Moines

Fly to

Central America

Route

Depart

Return

Price

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Fri 9/12

5:38 pm-12:45 pm

1 stop20h 07m

San José Juan Santamaria Intl

Fri 9/19

7:27 am-9:04 am

1 stop24h 37m

$299

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Sat 8/16

6:02 am-4:00 pm

1 stop10h 58m

San Salvador El Salvador Intl

Wed 8/27

8:00 am-10:28 pm

1 stop13h 28m

$365

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 10/20

5:51 pm-11:25 am

2 stops18h 34m

Guatemala City La Aurora

Thu 10/23

12:20 pm-4:59 pm

3 stops27h 39m

$384

Des MoinesBelize City

DSM - BZE

DSMBZE

Des Moines

Tue 11/11

3:18 pm-12:08 pm

2 stops20h 50m

Belize City Philip S.W.Goldson

Tue 11/18

4:21 pm-12:05 pm

2 stops19h 44m

$408

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 10/12

6:15 am-2:14 pm

1 stop7h 59m

Panama City Tocumen Intl

Tue 10/21

10:00 am-10:28 pm

1 stop12h 28m

$461

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Fri 9/12

4:09 pm-2:31 pm

2 stops22h 22m

Panama City Tocumen Intl

Fri 9/19

3:31 pm-3:16 pm

2 stops23h 45m

$465

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 10/2

5:44 am-11:30 am

1 stop6h 46m

Guatemala City La Aurora

Mon 10/6

12:56 pm-10:43 pm

1 stop8h 47m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 10/12

6:39 pm-12:56 pm

1 stop18h 17m

Panama City Tocumen Intl

Fri 10/17

2:21 pm-4:52 pm

2 stops26h 31m

$466

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Sat 8/16

6:50 pm-2:23 pm

2 stops20h 33m

San Salvador El Salvador Intl

Wed 8/27

1:25 pm-12:23 pm

2 stops21h 58m

$471

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Sat 11/8

6:00 pm-12:20 pm

2 stops18h 20m

San Salvador El Salvador Intl

Sat 11/15

2:29 pm-10:59 pm

1 stop8h 30m

$476

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Showing 1-10 of 35 results
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Best time to book a flight from Des Moines to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Central America

What is the cheapest month to book a flight from Des Moines to Central America?

Currently, September is the cheapest month in which you can book a flight from Des Moines to Central America (average of $398). Flying from Des Moines to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to CA?

Find hourly flight availability from Des Moines to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Central America as you normally would.

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated July 29, 2025.
Read through reviews of airlines operating flights from Des Moines to Central America, such as Southwest, Delta, and Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,238 reviews

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,238 reviews
Southwest
8.0
Very good
4,238 reviews

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,979 reviews
Southwest
8.0
Very good
4,238 reviews

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Copa Airlines
7.5
Good
1,493 reviews
Southwest
8.0
Very good
4,238 reviews

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,896 reviews
Southwest
8.0
Very good
4,238 reviews

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,238 reviews

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Central America?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Central America. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • What are the cheapest airlines to fly from Des Moines to Central America one-way?

    To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $198. American Airlines flights start at $245 while deals on Copa Airlines start at $288 one-way.

  • What are the most popular routes from Des Moines to Central America?

    The most popular flight routes from Des Moines to Central America are Des Moines - Panama City Tocumen Intl, Des Moines - San José Juan Santamaria Intl and Des Moines - Belize City Philip S.W.Goldson.

  • Can I find deals for flights from Des Moines to Central America that include hotel bookings?

    Yes. In addition to deals on Des Moines to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Central America.

  • Can I find deals for business class flights from Des Moines to Central America?

    Yes. Cheapflights offers flight deals from Des Moines to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Central America?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to Central America (average of $398). Flying from Des Moines to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Central America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Des Moines to Central America

Discover the top 3 airlines that operate flights from Des Moines to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$289Average$630FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$369Average$668FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$445Average$686FlexibilityNo cancel feeOn-time71%

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