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Central America

$139+ Cheap flights from Des Moines (DSM) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SJO
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Des Moines to Central America

Keep the following information in mind while searching for Des Moines to Central America flight deals. Data was last updated September 11, 2025.

Round-trip from

$332
(Kiwi.com)

One-way from

$139
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$526
From Des Moines to Central America
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One-way flight from Des Moines to Central America
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Highest demand for flights based on searches. 23% potential increase in price ($222 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($69 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Central America

Cheapest flights from Des Moines to Central America
Explore the most affordable flight options available from Des Moines to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/38:00 amDSM - GUA
2 stops28h 22mMultiple Airlines
Wed 11/121:22 pmGUA - DSM
1 stop20h 38mMultiple Airlines
Deal found 9/10$332
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/108:00 amDSM - GUA
2 stops28h 26mMultiple Airlines
Wed 11/191:22 pmGUA - DSM
1 stop19h 07mMultiple Airlines
Deal found 9/10$343
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/910:51 amDSM - SJO
1 stop25h 39mMultiple Airlines
Thu 10/1611:37 amSJO - DSM
1 stop19h 53mMultiple Airlines
Deal found 9/11$354
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/610:50 amDSM - SJO
1 stop25h 24mMultiple Airlines
Sat 11/151:19 pmSJO - DSM
1 stop20h 41mMultiple Airlines
Deal found 9/9$362
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/248:30 amDSM - SAL
1 stop23h 00mMultiple Airlines
Wed 10/298:00 amSAL - DSM
2 stops28h 47mMultiple Airlines
Deal found 9/10$366
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/28:47 pmDSM - SJO
2 stops15h 43mMultiple Airlines
Sat 11/151:19 pmSJO - DSM
1 stop20h 41mMultiple Airlines
Deal found 9/9$366
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/610:50 amDSM - SJO
1 stop25h 24mMultiple Airlines
Wed 11/191:19 pmSJO - DSM
1 stop19h 10mMultiple Airlines
Deal found 9/9$369
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/28:47 pmDSM - SJO
2 stops15h 43mMultiple Airlines
Wed 11/191:19 pmSJO - DSM
1 stop19h 10mMultiple Airlines
Deal found 9/9$373
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/31:43 pmDSM - SJO
2 stops22h 47mMultiple Airlines
Sat 11/151:19 pmSJO - DSM
1 stop20h 41mMultiple Airlines
Deal found 9/9$374
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/31:43 pmDSM - SJO
2 stops22h 47mMultiple Airlines
Wed 11/191:19 pmSJO - DSM
1 stop19h 10mMultiple Airlines
Deal found 9/9$381
This Mytrip deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/268:47 pmDSM - GUA
2 stops15h 35mMultiple Airlines
Sun 11/21:27 pmGUA - DSM
2 stops23h 26mMultiple Airlines
Deal found 9/11$383
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3112:05 pmDSM - SJO
2 stops24h 25mMultiple Airlines
Sat 11/151:19 pmSJO - DSM
1 stop20h 41mMultiple Airlines
Deal found 9/9$388

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Des Moines to Central America that are best for you.

Fly from

Des Moines

Fly to

Central America

Route

Depart

Return

Price

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 11/3

8:00 am-12:22 pm

2 stops28h 22m

Guatemala City La Aurora

Wed 11/12

1:22 pm-10:00 am

1 stop20h 38m

$332

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 11/10

8:00 am-12:26 pm

2 stops28h 26m

Guatemala City La Aurora

Wed 11/19

1:22 pm-8:29 am

1 stop19h 07m

$343

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Thu 10/9

10:51 am-11:30 am

1 stop25h 39m

San José Juan Santamaria Intl

Thu 10/16

11:37 am-8:30 am

1 stop19h 53m

$354

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 10/26

10:41 am-11:22 am

1 stop25h 41m

Guatemala City La Aurora

Sun 11/2

1:27 pm-12:53 pm

2 stops23h 26m

$417

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Tue 11/25

4:03 pm-12:14 pm

1 stop20h 11m

San José Juan Santamaria Intl

Wed 12/3

1:19 pm-9:36 pm

2 stops32h 17m

$422

Des MoinesBelize City

DSM - BZE

DSMBZE

Des Moines

Tue 11/11

5:34 am-12:32 pm

1 stop6h 58m

Belize City Philip S.W.Goldson

Tue 11/18

1:57 pm-10:33 pm

1 stop8h 36m

$452

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Thu 10/16

6:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

Mon 10/20

10:00 am-10:28 pm

1 stop12h 28m

$461

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 10/12

6:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

Mon 10/20

10:00 am-10:28 pm

1 stop12h 28m

$461

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Mon 10/6

6:39 pm-12:56 pm

1 stop18h 17m

Panama City Tocumen Intl

Wed 10/8

2:21 pm-10:30 pm

1 stop8h 09m

$461

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Tue 10/7

6:15 am-2:14 pm

1 stop7h 59m

Panama City Tocumen Intl

Fri 10/10

10:00 am-10:28 pm

1 stop12h 28m

$461

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 60 results
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Best time to book a flight from Des Moines to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Central America

What is the cheapest month to book a flight from Des Moines to Central America?

Currently, September is the cheapest month in which you can book a flight from Des Moines to Central America (average of $398). Flying from Des Moines to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to CA?

Find hourly flight availability from Des Moines to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Central America as you normally would.

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Des Moines to Central America, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Central America?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Central America. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Des Moines to Central America?

    Airlines like Delta, United Airlines, and Southwest fly from Des Moines to Central America in about 6h 58m. The time it takes to get you to your destination can typically vary by up to 7h 12m. The distance between Des Moines and Central America is about 1687 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Des Moines to Central America one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $157. United Airlines flights start at $198 while deals on American Airlines start at $204 one-way.

  • What are the most popular routes from Des Moines to Central America?

    The most popular flight routes from Des Moines to Central America are Des Moines - San Salvador El Salvador Intl, Des Moines - San José Juan Santamaria Intl and Des Moines - Panama City Tocumen Intl.

  • Can I find deals for flights from Des Moines to Central America that include hotel bookings?

    Yes. In addition to deals on Des Moines to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Central America.

  • Can I find deals for business class flights from Des Moines to Central America?

    Yes. Cheapflights offers flight deals from Des Moines to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Central America?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to Central America (average of $398). Flying from Des Moines to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Central America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Des Moines to Central America

Discover the top 3 airlines that operate flights from Des Moines to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$289Average$673FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$411Average$675FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$445Average$686FlexibilityNo cancel feeOn-time71%

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