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Central America

$114+ Cheap flights from Des Moines (DSM) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SJO
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Des Moines to Central America

Keep the following information in mind while searching for Des Moines to Central America flight deals. Data was last updated May 1, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$386
(Mytrip)

One-way from

$114
(Mytrip)

Popular in

December

Cheapest in

September

Average price

$590
Provider with most accurate pricing for Des Moines-San Salvador El Salvador Intl flight deals.
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Provider most trusted by Cheapflights users for Des Moines-San Salvador El Salvador Intl flights.
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From Des Moines to Central America
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One-way flight from Des Moines to Central America
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Highest demand for flights based on searches. 20% potential increase in price ($190 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($58 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Des Moines to Central America

Cheapest flights from Des Moines to Central America
Explore the most affordable flight options available from Des Moines to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/291:06 pmDSM - SJO
2 stops22h 21mMultiple Airlines
Thu 6/511:32 amSJO - DSM
1 stop29h 57mMultiple Airlines
Deal found 4/30$386
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/141:15 pmDSM - GUA
2 stops23h 14mMultiple Airlines
Fri 6/2012:59 amGUA - DSM
2 stops15h 17mMultiple Airlines
Deal found 4/30$420
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/185:00 amDSM - SAL
2 stops15h 56mAmerican Airlines
Fri 7/256:00 amSAL - DSM
2 stops16h 49mAmerican Airlines
Deal found 4/30$424
This Kissandfly.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/135:52 pmDSM - PTY
2 stops25h 10mKLM
Fri 6/202:23 pmPTY - DSM
2 stops19h 15mKLM
Deal found 4/30$435
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/28:00 amDSM - PTY
1 stop8h 12mUnited Airlines
Mon 5/57:55 amPTY - DSM
1 stop14h 50mUnited Airlines
Deal found 4/30$441
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/246:30 amDSM - PTY
2 stops13h 23mDelta
Sat 5/318:00 amPTY - DSM
1 stop9h 50mDelta
Deal found 4/29$446
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/135:32 pmDSM - PTY
2 stops19h 28mAmerican Airlines
Fri 6/201:50 pmPTY - DSM
2 stops19h 14mAmerican Airlines
Deal found 4/29$447
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/16:30 amDSM - SAL
1 stop14h 05mMultiple Airlines
Sat 6/149:10 amSAL - DSM
1 stop25h 39mMultiple Airlines
Deal found 4/30$450
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/305:00 amDSM - SJO
1 stop18h 04mAmerican Airlines
Fri 7/1111:59 pmSJO - DSM
1 stop8h 04mAmerican Airlines
Deal found 4/30$506
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/18:00 amDSM - SAL
1 stop13h 17mUnited Airlines
Sat 5/101:25 pmSAL - DSM
1 stop8h 20mUnited Airlines
Deal found 4/30$507
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/205:27 pmDSM - MGA
2 stops18h 54mAmerican Airlines
Fri 5/301:55 pmMGA - DSM
2 stops21h 23mAmerican Airlines
Deal found 4/29$513
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/117:13 amDSM - BZE
1 stop6h 27mAmerican Airlines
Tue 11/182:40 pmBZE - DSM
1 stop7h 09mAmerican Airlines
Deal found 4/30$514

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Des Moines to Central America that are best for you.

Fly from

Des Moines

Fly to

Central America

Route

Depart

Return

Price

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Thu 5/29

1:06 pm-10:27 am

2 stops22h 21m

San José Juan Santamaria Intl

Thu 6/5

11:32 am-6:29 pm

1 stop29h 57m

$386

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sat 6/14

1:15 pm-11:29 am

2 stops23h 14m

Guatemala City La Aurora

Fri 6/20

12:59 am-5:16 pm

2 stops15h 17m

$420

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Fri 7/18

5:00 am-7:56 pm

2 stops15h 56m

San Salvador El Salvador Intl

Fri 7/25

6:00 am-11:49 pm

2 stops16h 49m

$424

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Fri 6/13

5:52 pm-7:02 pm

2 stops25h 10m

Panama City Tocumen Intl

Fri 6/20

2:23 pm-9:38 am

2 stops19h 15m

$435

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 5/17

5:35 am-12:48 pm

1 stop7h 13m

Panama City Tocumen Intl

Sat 5/24

2:13 pm-10:30 pm

1 stop8h 17m

$441

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Fri 6/13

5:32 pm-1:00 pm

2 stops19h 28m

Panama City Tocumen Intl

Fri 6/20

1:50 pm-9:04 am

2 stops19h 14m

$447

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 5/24

3:01 pm-4:12 pm

1 stop25h 11m

Panama City Tocumen Intl

Sat 5/31

7:55 am-10:32 pm

1 stop14h 37m

$450

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Sun 6/1

6:30 am-7:35 pm

1 stop14h 05m

San Salvador El Salvador Intl

Sat 6/14

9:10 am-11:49 am

1 stop25h 39m

$450

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Mon 6/30

5:00 am-10:04 pm

1 stop18h 04m

San José Juan Santamaria Intl

Fri 7/11

11:59 pm-9:03 am

1 stop8h 04m

$506

Des MoinesManagua

DSM - MGA

DSMMGA

Des Moines

Tue 5/20

5:27 pm-11:21 am

2 stops18h 54m

Managua Augusto C Sandino

Fri 5/30

1:55 pm-12:18 pm

2 stops21h 23m

$513

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 37 results
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Best time to book a flight from Des Moines to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Central America

What is the cheapest month to book a flight from Des Moines to Central America?

Currently, September is the cheapest month in which you can book a flight from Des Moines to Central America (average of $398). Flying from Des Moines to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to CA?

Find hourly flight availability from Des Moines to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Central America as you normally would.

Rainfall in Central America by month

Plan your trip to Central America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Central America ranges from 0.0 - 13.0 inches per month. August is typically the wettest month, when rainfall can reach 13.0 in. February is typically the driest time to visit Central America when rainfall is around 0.0 in.

Temperature in Central America by month

Plan your trip to Central America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Central America, use this chart to help with planning. For those seeking warmer temperatures, March is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated May 1, 2025.
Southwest
8.0
Very good
4,294 reviews

Entertainment

7.6

Crew

8.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,294 reviews
Southwest
8.0
Very good
4,294 reviews

Entertainment

7.6

Crew

8.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,934 reviews
Southwest
8.0
Very good
4,294 reviews

Entertainment

7.6

Crew

8.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
KLM
7.8
Good
1,334 reviews
Southwest
8.0
Very good
4,294 reviews

Entertainment

7.6

Crew

8.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,294 reviews

Entertainment

7.6

Crew

8.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,294 reviews

Entertainment

7.6

Crew

8.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Central America?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Central America. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • What are the cheapest airlines to fly from Des Moines to Central America one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $188. United Airlines flights start at $203 while deals on American Airlines start at $257 one-way.

  • What are the most popular routes from Des Moines to Central America?

    The most popular flight routes from Des Moines to Central America are Des Moines - San Salvador El Salvador Intl, Des Moines - Belize City Philip S.W.Goldson and Des Moines - San José Juan Santamaria Intl.

  • Can I find deals for flights from Des Moines to Central America that include hotel bookings?

    Yes. In addition to deals on Des Moines to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Central America.

  • Can I find deals for business class flights from Des Moines to Central America?

    Yes. Cheapflights offers flight deals from Des Moines to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Central America?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to Central America (average of $398). Flying from Des Moines to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Central America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Des Moines to Central America

Discover the top 4 airlines that operate flights from Des Moines to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$289Average$625FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$349Average$677FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$354Average$668FlexibilityNo cancel feeOn-time71%
AviancaCheapest$456Average$564FlexibilityNo cancel feeOn-time71%

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