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Central America

$133+ Cheap flights from Des Moines (DSM) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SJO
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Des Moines to Central America

Cheapest flights from Des Moines to Central America
Explore the most affordable flight options available from Des Moines to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:34 amDSM - PTY
1 stop13h 25mDelta
Fri 12/268:00 amPTY - DSM
1 stop10h 15mDelta
Deal found 12/10$462
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:46 pmDSM - PTY
2 stops21h 21mUnited Airlines
Mon 3/233:41 pmPTY - DSM
2 stops21h 42mUnited Airlines
Deal found 12/11$508
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:52 pmDSM - PTY
2 stops20h 02mAmerican Airlines
Mon 3/231:39 pmPTY - DSM
2 stops23h 31mAmerican Airlines
Deal found 12/10$561
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2311:00 amDSM - SJO
1 stop24h 42mMultiple Airlines
Tue 12/301:31 pmSJO - DSM
1 stop9h 39mMultiple Airlines
Deal found 12/11$593
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:07 amDSM - LIR
1 stop7h 09mAmerican Airlines
Wed 1/71:21 pmLIR - DSM
2 stops21h 29mAmerican Airlines
Deal found 12/10$604
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:45 pmDSM - SAL
1 stop23h 02mMultiple Airlines
Wed 1/73:52 pmSAL - DSM
1 stop30h 54mMultiple Airlines
Deal found 12/10$609
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:56 pmDSM - SJO
1 stop21h 29mMultiple Airlines
Thu 12/181:31 pmSJO - DSM
1 stop9h 05mMultiple Airlines
Deal found 12/10$611
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:34 amDSM - SAL
1 stop7h 37mDelta
Sun 12/212:32 pmSAL - DSM
1 stop7h 59mDelta
Deal found 12/11$614
This Mytrip deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:45 pmDSM - GUA
2 stops19h 40mMultiple Airlines
Thu 1/82:11 pmGUA - DSM
2 stops25h 29mMultiple Airlines
Deal found 12/10$628
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/128:15 amDSM - BZE
1 stop6h 17mUnited Airlines
Fri 12/193:38 pmBZE - DSM
1 stop6h 52mUnited Airlines
Deal found 12/11$634
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:45 pmDSM - GUA
2 stops43h 40mMultiple Airlines
Tue 12/303:00 pmGUA - DSM
1 stop29h 27mMultiple Airlines
Deal found 12/10$635
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/213:44 pmDSM - SJO
1 stop19h 58mMultiple Airlines
Tue 12/301:31 pmSJO - DSM
1 stop9h 39mMultiple Airlines
Deal found 12/11$637

Find flight deals from Des Moines to Central America

Keep the following information in mind while searching for Des Moines to Central America flight deals. Data was last updated December 12, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$344
(Mytrip)

One-way from

$133
(Trip.com)

Popular in

December

Cheapest in

September

Average price

$1,475
Provider with most accurate pricing for Des Moines-San Salvador El Salvador Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-San Salvador El Salvador Intl flights.
Search Deals
From Des Moines to Central America
Search Deals
One-way flight from Des Moines to Central America
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($222 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($69 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Des Moines to Central America that are best for you.

Fly from

Des Moines

Fly to

Central America

Route

Depart

Return

Price

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 1/22

2:58 pm-11:20 am

2 stops20h 22m

Guatemala City La Aurora

Thu 1/29

1:28 pm-10:46 pm

1 stop9h 18m

$345

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Sun 2/1

11:35 am-11:43 pm

1 stop12h 08m

San José Juan Santamaria Intl

Wed 2/11

2:54 pm-11:23 pm

1 stop8h 29m

$398

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Sun 2/1

6:48 pm-12:56 pm

1 stop18h 08m

San José Juan Santamaria Intl

Wed 2/11

6:30 am-10:30 pm

1 stop16h 00m

$398

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Sun 1/25

5:49 pm-10:15 pm

2 stops28h 26m

San José Juan Santamaria Intl

Tue 2/3

7:00 am-9:41 am

2 stops26h 41m

$412

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 1/25

2:58 pm-11:20 am

2 stops20h 22m

Guatemala City La Aurora

Sun 2/1

1:28 pm-10:46 pm

1 stop9h 18m

$413

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Wed 1/28

6:48 pm-12:56 pm

1 stop18h 08m

San José Juan Santamaria Intl

Mon 2/2

6:30 am-10:30 pm

1 stop16h 00m

$418

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Fri 2/6

7:43 am-9:02 pm

2 stops13h 19m

San José Juan Santamaria Intl

Fri 2/13

12:31 am-10:47 am

1 stop10h 16m

$442

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Mon 2/2

8:10 am-9:19 pm

1 stop13h 09m

San Salvador El Salvador Intl

Mon 2/9

2:50 pm-10:30 pm

1 stop7h 40m

$450

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Wed 4/1

8:00 am-8:49 pm

1 stop13h 49m

San Salvador El Salvador Intl

Wed 4/15

6:00 am-10:30 pm

1 stop15h 30m

$450

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Tue 4/14

3:00 pm-8:49 pm

1 stop6h 49m

San Salvador El Salvador Intl

Wed 4/22

6:00 am-10:30 pm

1 stop15h 30m

$450

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 55 results
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Best time to book a flight from Des Moines to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Central America

What is the cheapest month to book a flight from Des Moines to Central America?

Currently, April is the cheapest month in which you can book a flight from Des Moines to Central America (average of $289). Flying from Des Moines to Central America in December is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to CA?

Find hourly flight availability from Des Moines to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

A simple way to save on the total cost of your ticket is to fly from Des Moines to Central America at noon. If you’re flexible enough to do this you can expect to save up to 19% on your trip compared to booking a flight in the evening.

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated December 12, 2025.
Read through reviews of airlines operating flights from Des Moines to Central America, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,095 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Central America?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Central America. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Des Moines to Central America?

    Airlines like American Airlines, United Airlines, and Delta fly from Des Moines to Central America in about 12h 08m. The time it takes to get you to your destination can typically vary by up to 16h 18m. The distance between Des Moines and Central America is about 2253 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Des Moines to Central America one-way?

    To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $193. Delta flights start at $259 while deals on American Airlines start at $295 one-way.

  • What are the most popular routes from Des Moines to Central America?

    The most popular flight routes from Des Moines to Central America are Des Moines - Panama City Tocumen Intl, Des Moines - San Salvador El Salvador Intl and Des Moines - San José Juan Santamaria Intl.

  • Can I find deals for flights from Des Moines to Central America that include hotel bookings?

    Yes. In addition to deals on Des Moines to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Central America.

  • Can I find deals for business class flights from Des Moines to Central America?

    Yes. Cheapflights offers flight deals from Des Moines to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Central America?

    Currently, April is the cheapest month in which you can book a flight from Des Moines to Central America (average of $289). Flying from Des Moines to Central America in December is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Des Moines to Central America

Discover the top 3 airlines that operate flights from Des Moines to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$289Average$632FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$420Average$644FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$468Average$731FlexibilityNo cancel feeOn-time71%

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