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South Carolina

$94+ Cheap flights from San Francisco (SFO) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — CHS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from San Francisco to South Carolina

Keep the following information in mind while searching for San Francisco to South Carolina flight deals. Data was last updated September 11, 2025.

Round-trip from

$182
(Southwest)

One-way from

$94
(Orbitz)

Popular in

December

Cheapest in

September

Average price

$422
From San Francisco to South Carolina
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One-way flight from San Francisco to South Carolina
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Highest demand for flights based on searches. 4% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from San Francisco to South Carolina

Cheapest flights from San Francisco to South Carolina
Explore the most affordable flight options available from San Francisco to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/283:50 pmSFO - SAV
2 stops15h 10mSouthwest
Tue 11/47:05 amSAV - SFO
1 stop9h 15mSouthwest
Deal found 9/11$182
This Breeze Airways deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2612:50 pmSFO - CHS
1 stop6h 53mBreeze Airways
Sat 11/16:25 amCHS - SFO
1 stop8h 29mBreeze Airways
Deal found 9/11$231
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/112:39 pmSFO - CHS
1 stop7h 20mMultiple Airlines
Mon 10/63:33 pmCHS - SFO
2 stops46h 22mMultiple Airlines
Deal found 9/9$232
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/288:00 amSFO - CHS
1 stop8h 04mAmerican Airlines
Fri 10/3112:15 pmCHS - SFO
2 stops9h 35mAmerican Airlines
Deal found 9/10$238
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2712:47 pmSFO - CHS
1 stop6h 41mMultiple Airlines
Tue 11/42:59 pmCHS - SFO
2 stops34h 28mMultiple Airlines
Deal found 9/10$239
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2312:22 amSFO - SAV
1 stop9h 02mAmerican Airlines
Wed 12/317:38 pmSAV - SFO
1 stop7h 54mAmerican Airlines
Deal found 9/10$239
This Breeze Airways deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/612:50 pmSFO - CHS
1 stop6h 53mBreeze Airways
Sun 11/97:05 amCHS - SFO
1 stop8h 00mBreeze Airways
Deal found 9/10$244
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:37 amSFO - SAV
1 stop9h 10mAmerican Airlines
Tue 1/66:58 amSAV - SFO
1 stop7h 55mAmerican Airlines
Deal found 9/11$244
This Priceline deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2412:39 pmSFO - CHS
1 stop7h 20mBreeze Airways
Wed 10/16:25 amCHS - SFO
1 stop8h 29mBreeze Airways
Deal found 9/10$245
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1410:15 pmSFO - CHS
1 stop8h 16mAmerican Airlines
Wed 1/145:32 amCHS - SFO
2 stops9h 43mAmerican Airlines
Deal found 9/10$248
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/3012:47 amSFO - SAV
1 stop7h 53mAmerican Airlines
Wed 10/153:36 pmSAV - SFO
1 stop9h 20mAmerican Airlines
Deal found 9/10$249
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/111:36 pmSFO - MYR
1 stop8h 57mAmerican Airlines
Wed 11/53:32 pmMYR - SFO
1 stop7h 58mAmerican Airlines
Deal found 9/10$249

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from San Francisco to South Carolina that are best for you.

Fly from

San Francisco

Fly to

South Carolina

Route

Depart

Return

Price

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Thu 11/6

12:50 pm-10:43 pm

1 stop6h 53m

Charleston

Sun 11/9

7:05 am-12:05 pm

1 stop8h 00m

$244

San FranciscoMyrtle Beach

SFO - MYR

SFOMYR

San Francisco

Sat 11/1

11:36 pm-10:33 am

1 stop8h 57m

Myrtle Beach Intl

Wed 11/5

3:32 pm-8:30 pm

1 stop7h 58m

$249

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Fri 10/17

12:47 pm-10:28 pm

1 stop6h 41m

Charleston

Mon 10/20

7:05 am-12:02 pm

1 stop7h 57m

$268

San FranciscoSavannah

SFO - SAV

SFOSAV

San Francisco

Fri 10/24

9:50 pm-9:17 am

1 stop8h 27m

Savannah/Hilton Head

Mon 10/27

3:33 pm-9:03 pm

1 stop8h 30m

$277

San FranciscoSavannah

SFO - SAV

SFOSAV

San Francisco

Fri 11/14

11:20 pm-10:46 am

1 stop8h 26m

Savannah/Hilton Head

Mon 11/17

7:05 pm-1:15 am

1 stop9h 10m

$277

San FranciscoSavannah

SFO - SAV

SFOSAV

San Francisco

Sat 11/8

7:15 am-4:39 pm

1 stop6h 24m

Savannah/Hilton Head

Wed 11/12

6:58 pm-11:58 pm

1 stop8h 00m

$277

San FranciscoSavannah

SFO - SAV

SFOSAV

San Francisco

Wed 10/29

1:45 pm-11:58 pm

1 stop7h 13m

Savannah/Hilton Head

Sun 11/2

5:40 am-9:58 am

1 stop7h 18m

$277

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Wed 10/8

1:45 pm-11:55 pm

1 stop7h 10m

Greenville

Wed 10/15

3:10 pm-6:56 pm

1 stop6h 46m

$277

San FranciscoSavannah

SFO - SAV

SFOSAV

San Francisco

Wed 10/1

10:15 am-10:37 pm

2 stops9h 22m

Savannah/Hilton Head

Wed 10/15

12:35 pm-7:23 pm

1 stop9h 48m

$279

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Mon 11/24

11:39 pm-3:03 pm

1 stop12h 24m

Charleston

Sat 11/29

5:25 pm-11:30 pm

1 stop9h 05m

$283

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 60 results
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Best time to book a flight from San Francisco to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to South Carolina

What is the cheapest month to book a flight from San Francisco to South Carolina?

Currently, August is the cheapest month in which you can book a flight from San Francisco to South Carolina (average of $217). Flying from San Francisco to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to SC?

Find hourly flight availability from San Francisco to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from San Francisco to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from San Francisco to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Southwest, Breeze Airways, and Delta from San Francisco to South Carolina to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Breeze Airways
8.0
Very good
205 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,960 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
8,937 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Francisco to South Carolina?

    For a flight from San Francisco to South Carolina, you will be flying from San Francisco. San Francisco (SFO) is just 11.8 mi from the center of the city.

  • How long is the flight from San Francisco to South Carolina?

    A quick flight from San Francisco to South Carolina can take about 6h 53m. Breeze Airways provides one of the quickest options available for as low as $244. San Francisco and South Carolina are separated by a distance of 2389 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from San Francisco to South Carolina one-way?

    One-way options have recently been found by users for as low as $97 on Breeze Airways. Other airlines that offer cheap prices include Southwest from $107 and American Airlines from $125 one-way.

  • What are the most popular routes from San Francisco to South Carolina?

    Most travelers choose San Francisco - Charlotte Douglas, San Francisco - Savannah/Hilton Head or San Francisco - Charleston when deciding on the best route from San Francisco to South Carolina.

  • Can I find deals for flights from San Francisco to South Carolina that include hotel bookings?

    Yes. In addition to deals on San Francisco to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to South Carolina.

  • Can I find deals for business class flights from San Francisco to South Carolina?

    Yes. Cheapflights offers flight deals from San Francisco to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from San Francisco to South Carolina (average of $217). Flying from San Francisco to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Francisco to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from San Francisco to South Carolina

Discover the top 5 airlines that operate flights from San Francisco to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$174Average$341FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$216Average$483FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$265Average$546FlexibilityNo cancel feeOn-time69%
DeltaCheapest$276Average$465FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$298Average$496FlexibilityNo cancel feeOn-time63%

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