South Carolina

$74+ Cheap flights from San Francisco (SFO) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/8. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — CHS
Jan 11 — Jan 181
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Cheap flight deals from San Francisco to South Carolina

Cheapest flights from San Francisco to South Carolina
Explore the most affordable flight options available from San Francisco to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:24 amSFO - CLT
1 stop25h 58mFrontier
Mon 1/53:07 pmCLT - SFO
2 stops34h 52mFrontier
Deal found 12/11$289
This Alaska Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:41 pmSFO - CHS
1 stop17h 16mAlaska Airlines
Wed 1/77:22 pmCHS - SFO
1 stop29h 36mAlaska Airlines
Deal found 12/10$331
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2911:20 pmSFO - CLT
2 stops13h 36mMultiple Airlines
Fri 1/96:50 pmCLT - SFO
1 stop8h 34mMultiple Airlines
Deal found 12/11$335
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:12 pmSFO - CLT
2 stops17h 07mFrontier
Fri 1/96:50 pmCLT - SFO
1 stop8h 34mFrontier
Deal found 12/11$355
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:00 amSFO - CHS
1 stop9h 28mAmerican Airlines
Wed 1/75:24 pmCHS - SFO
1 stop8h 01mAmerican Airlines
Deal found 12/11$367
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:16 pmSFO - CLT
1 stop17h 26mMultiple Airlines
Tue 1/69:34 pmCLT - SFO
2 stops37h 19mMultiple Airlines
Deal found 12/11$367
This CheapOair deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:30 amSFO - CLT
1 stop7h 19mFrontier
Sun 12/145:44 pmCLT - SFO
1 stop17h 09mFrontier
Deal found 12/10$368
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:16 pmSFO - CLT
1 stop17h 26mMultiple Airlines
Thu 1/811:12 amCLT - SFO
2 stops23h 51mMultiple Airlines
Deal found 12/11$380
This Southwest deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:25 amSFO - CLT
1 stop9h 45mSouthwest
Mon 12/2212:50 pmCLT - SFO
2 stops12h 10mSouthwest
Deal found 12/11$382
This CheapOair deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/114:07 pmSFO - CLT
1 stop21h 42mFrontier
Sun 12/145:44 pmCLT - SFO
1 stop17h 09mFrontier
Deal found 12/10$398
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:25 amSFO - SAV
1 stop9h 38mAmerican Airlines
Tue 1/64:33 pmSAV - SFO
1 stop8h 04mAmerican Airlines
Deal found 12/11$405
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:30 pmSFO - CLT
2 stops34h 52mFrontier
Mon 1/126:50 pmCLT - SFO
1 stop28h 56mFrontier
Deal found 12/9$412

Find flight deals from San Francisco to South Carolina

Keep the following information in mind while searching for San Francisco to South Carolina flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$251
(American Airlines)

One-way from

$74
(Frontier)

Popular in

December

Cheapest in

November

Average price

$866
Provider with most accurate pricing for San Francisco-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for San Francisco-Myrtle Beach Intl flights.
From San Francisco to South Carolina
One-way flight from San Francisco to South Carolina
Highest demand for flights based on searches. 7% potential increase in price ($40 potential increase over avg. RT price).
Cheapest flight prices on average. 6% potential price decrease ($33 potential savings vs. average RT price).
Average for round-trip flights in December 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from San Francisco to South Carolina that are best for you.

Fly from

San Francisco

Fly to

South Carolina

Route

Depart

Return

Price

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Wed 2/18

9:50 am-8:50 pm

1 stop8h 00m

Charleston

Wed 2/25

1:45 pm-9:20 pm

2 stops10h 35m

$256

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Sat 1/10

5:45 am-5:43 pm

1 stop8h 58m

Charleston

Sat 1/17

6:00 am-12:39 pm

1 stop9h 39m

$257

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Thu 2/19

6:30 am-5:32 pm

1 stop8h 02m

Charleston

Mon 2/23

6:32 pm-10:37 am

1 stop19h 05m

$262

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Thu 2/19

11:10 am-9:40 pm

1 stop7h 30m

Charleston

Wed 2/25

1:45 pm-9:20 pm

2 stops10h 35m

$262

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Sat 3/28

11:20 pm-10:02 am

1 stop7h 42m

Charleston

Wed 4/1

4:05 pm-10:43 pm

1 stop9h 38m

$263

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Thu 1/8

8:34 pm-9:20 am

1 stop9h 46m

Charleston

Mon 1/12

12:09 pm-10:59 pm

1 stop13h 50m

$263

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Thu 1/8

5:00 am-4:17 pm

1 stop8h 17m

Charleston

Mon 1/12

7:45 pm-1:30 am

1 stop8h 45m

$263

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Thu 1/29

10:54 pm-11:09 am

1 stop9h 15m

Charleston

Sun 2/1

12:53 pm-7:49 pm

1 stop9h 56m

$263

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Fri 1/23

11:55 pm-11:40 am

1 stop8h 45m

Charleston

Mon 1/26

5:13 pm-11:59 pm

1 stop9h 46m

$263

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Sun 1/4

10:45 pm-10:59 am

1 stop9h 14m

Charleston

Tue 1/13

5:25 am-12:55 pm

1 stop10h 30m

$308

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 60 results
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Best time to book a flight from San Francisco to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to South Carolina

What is the cheapest month to book a flight from San Francisco to South Carolina?

Currently, May is the cheapest month in which you can book a flight from San Francisco to South Carolina (average of $148). Flying from San Francisco to South Carolina in March is currently the most expensive (average of $276). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to SC?

Find hourly flight availability from San Francisco to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 1% on flights from San Francisco to South Carolina by exploring options for tickets at noon.

What is the cheapest day to fly from San Francisco to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to South Carolina flight should consider departing on Saturday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 12, 2025.
Peruse reviews from past customers who have flown with Breeze Airways, Southwest, and Delta from San Francisco to South Carolina to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.4

Overall

8.2

Comfort

8.2

Crew

8.8

Food

6.7

Entertainment

6.6

Reviews

1 / 15
8.0
Excellent

Lyle,Dec 2025

BDL - RSW

Seating was comfortable, crew excellent, no food or entertainment offered.

Boarding

8.4

Overall

8.2

Comfort

8.2

Crew

8.8

Food

6.7

Entertainment

6.6

Reviews

1 / 15
8.0
Excellent

Lyle,Dec 2025

BDL - RSW

Seating was comfortable, crew excellent, no food or entertainment offered.

Boarding

8.4

Overall

8.2

Comfort

8.2

Crew

8.8

Food

6.7

Entertainment

6.6

Reviews

1 / 15
8.0
Excellent

Lyle,Dec 2025

BDL - RSW

Seating was comfortable, crew excellent, no food or entertainment offered.

Boarding

8.4

Overall

8.2

Comfort

8.2

Crew

8.8

Food

6.7

Entertainment

6.6

Reviews

1 / 15
8.0
Excellent

Lyle,Dec 2025

BDL - RSW

Seating was comfortable, crew excellent, no food or entertainment offered.

Boarding

8.4

Overall

8.2

Comfort

8.2

Crew

8.8

Food

6.7

Entertainment

6.6

Reviews

1 / 15
8.0
Excellent

Lyle,Dec 2025

BDL - RSW

Seating was comfortable, crew excellent, no food or entertainment offered.

Boarding

8.4

Overall

8.2

Comfort

8.2

Crew

8.8

Food

6.7

Entertainment

6.6

Reviews

1 / 15
8.0
Excellent

Lyle,Dec 2025

BDL - RSW

Seating was comfortable, crew excellent, no food or entertainment offered.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Francisco to South Carolina?

    For a flight from San Francisco to South Carolina, you will be flying from San Francisco. San Francisco (SFO) is just 11.8 mi from the center of the city.

  • How long is the flight from San Francisco to South Carolina?

    A quick flight from San Francisco to South Carolina can take about 8h. Southwest provides one of the quickest options available for as low as $256. San Francisco and South Carolina are separated by a distance of 2389 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from San Francisco to South Carolina one-way?

    One-way options have recently been found by users for as low as $89 on Breeze Airways. Other airlines that offer cheap prices include Southwest from $102 and American Airlines from $125 one-way.

  • What are the most popular routes from San Francisco to South Carolina?

  • Can I find deals for flights from San Francisco to South Carolina that include hotel bookings?

    Yes. In addition to deals on San Francisco to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to South Carolina.

  • Can I find deals for business class flights from San Francisco to South Carolina?

    Yes. Cheapflights offers flight deals from San Francisco to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to South Carolina?

    Currently, May is the cheapest month in which you can book a flight from San Francisco to South Carolina (average of $148). Flying from San Francisco to South Carolina in March is currently the most expensive (average of $276). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for San Francisco to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from San Francisco to South Carolina

Discover the top 6 airlines that operate flights from San Francisco to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$167Average$287FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$236Average$464FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$266Average$508FlexibilityNo cancel feeOn-time69%
JetBlueCheapest$270Average$362FlexibilityNo cancel feeOn-time62%
DeltaCheapest$276Average$482FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$286Average$496FlexibilityNo cancel feeOn-time63%

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