$284+ Cheap flights from Panama to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/19. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from Panama to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama to South Carolina
Keep the following information in mind while searching for Panama to South Carolina flight deals. Data was last updated April 30, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $393 (Delta) |
One-way from | $284 (Delta) |
Find flight deals from Panama to South Carolina
Cheapest flights from Panama to South CarolinaExplore the most affordable flight options available from Panama to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.
Explore the most affordable flight options available from Panama to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Avianca Connect deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Avianca deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Ovago deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Panama to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Panama CityCharleston
PTY - CHS
PTYCHS
Panama City Tocumen Intl
Fri 7/25
2:23 pm-11:59 pm
1 stop8h 36m
Charleston
Sat 8/2
6:18 am-1:03 pm
1 stop7h 45m
Panama CityCharleston
PTY - CHS
PTYCHS
Panama City Tocumen Intl
Fri 7/25
3:10 pm-10:18 am
2 stops18h 08m
Charleston
Sat 8/2
6:00 am-2:15 pm
1 stop9h 15m
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Thu 6/19
2:23 pm-11:59 pm
1 stop8h 36m
Charlotte Douglas
Mon 6/30
6:52 am-1:08 pm
1 stop7h 16m
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Fri 9/5
1:50 pm-12:39 am
1 stop9h 49m
Charlotte Douglas
Fri 9/12
5:35 am-12:25 pm
1 stop7h 50m
Panama CityFlorence
PTY - FLO
PTYFLO
Panama City Tocumen Intl
Sat 6/28
1:50 pm-10:39 am
2 stops19h 49m
Florence
Sun 7/6
11:12 am-2:15 pm
2 stops28h 03m
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Sat 5/10
3:40 pm-11:03 am
2 stops18h 23m
Charlotte Douglas
Sat 5/17
11:23 am-12:10 am
2 stops13h 47m
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Wed 5/21
3:30 pm-10:16 pm
1 stop29h 46m
Charlotte Douglas
Fri 5/30
5:05 pm-6:37 pm
1 stop26h 32m
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Thu 5/15
5:25 pm-9:45 am
2 stops15h 20m
Charlotte Douglas
Sun 5/18
6:00 am-12:10 am
2 stops19h 10m
Panama CityMyrtle Beach
PTY - MYR
PTYMYR
Panama City Tocumen Intl
Sat 6/28
10:55 pm-10:02 am
1 stop10h 07m
Myrtle Beach Intl
Sun 7/6
10:58 am-7:31 pm
1 stop9h 33m
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Thu 6/19
2:23 pm-10:52 pm
1 stop7h 29m
Best time to book a flight from Panama to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Panama with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Panama to South Carolina
What is the cheapest month to book a flight from Panama to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Panama to South Carolina (average of $217). Flying from Panama to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PA to SC?
Find hourly flight availability from Panama to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to South Carolina as you normally would.
Rainfall in South Carolina by month
Plan your trip to South Carolina by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.
Temperature in South Carolina by month
Plan your trip to South Carolina by taking into account the average temperature totals by month.
If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 30, 2025.
Read reviews from past customers who have flown Delta, United Airlines and American Airlines from Panama to South Carolina. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
Boarding
Overall
Crew
Food
Comfort
Reviews
Aaron,Oct 2024
TUS - LAX
Entertainment
Boarding
Overall
Crew
Food
Comfort
Reviews
Aaron,Oct 2024
TUS - LAX
Entertainment
Boarding
Overall
Crew
Food
Comfort
Reviews
Aaron,Oct 2024
TUS - LAX
Entertainment
Boarding
Overall
Crew
Food
Comfort
Reviews
Aaron,Oct 2024
TUS - LAX
Entertainment
Boarding
Overall
Crew
Food
Comfort
Reviews
Aaron,Oct 2024
TUS - LAX
Related info for your journey
Find useful and relevant information for your journey from Panama to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes for Panama to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Top airline flying from Panama to South Carolina
Discover the top airline that operate flights from Panama to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$423 | Average$501 | FlexibilityNo cancel fee | On-time71% |