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South Carolina

$78+ Cheap flights from Mississippi to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — CHS
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Mississippi to South Carolina

Cheapest flights from Mississippi to South Carolina
Explore the most affordable flight options available from Mississippi to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:15 am
MEM
-
CLT
1 stop19h 43m
Multiple Airlines
Mon 3/210:42 pm
CLT
-
MEM
1 stop12h 38m
Multiple Airlines
Deal found 1/27$171
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:15 am
MEM
-
CLT
1 stop27h 14m
Multiple Airlines
Fri 2/2710:20 pm
CLT
-
MEM
1 stop13h 00m
Multiple Airlines
Deal found 1/27$183
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:15 am
MEM
-
CLT
1 stop25h 36m
Multiple Airlines
Thu 3/55:55 am
CLT
-
MEM
1 stop12h 31m
Multiple Airlines
Deal found 1/27$184
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/58:35 pm
MEM
-
CLT
1 stop14h 26m
Multiple Airlines
Sun 2/88:36 am
CLT
-
MEM
1 stop12h 09m
Multiple Airlines
Deal found 1/26$189
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:15 am
MEM
-
CLT
1 stop19h 43m
Multiple Airlines
Mon 3/210:42 pm
CLT
-
MEM
1 stop12h 38m
Multiple Airlines
Deal found 1/27$190
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:15 am
MEM
-
CLT
1 stop19h 43m
Multiple Airlines
Sun 3/19:52 pm
CLT
-
MEM
1 stop13h 28m
Multiple Airlines
Deal found 1/27$191
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/58:35 pm
MEM
-
CLT
1 stop14h 26m
Multiple Airlines
Tue 2/105:54 pm
CLT
-
MEM
2 stops49h 15m
Multiple Airlines
Deal found 1/25$195
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:07 pm
MEM
-
CLT
1 stop14h 19m
Multiple Airlines
Mon 3/210:42 pm
CLT
-
MEM
1 stop12h 38m
Multiple Airlines
Deal found 1/26$196
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/127:04 pm
MEM
-
CLT
2 stops18h 14m
Multiple Airlines
Mon 2/1610:42 pm
CLT
-
MEM
1 stop12h 38m
Multiple Airlines
Deal found 1/26$198
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/84:52 pm
MEM
-
CHS
1 stop4h 07m
Multiple Airlines
Sun 2/156:15 am
CHS
-
MEM
2 stops13h 04m
Multiple Airlines
Deal found 1/27$222
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1111:15 am
MEM
-
CHS
1 stop20h 23m
Multiple Airlines
Thu 3/1212:57 pm
CHS
-
MEM
1 stop4h 15m
Multiple Airlines
Deal found 1/26$234
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1011:15 am
MEM
-
CHS
2 stops27h 50m
Multiple Airlines
Thu 3/1212:57 pm
CHS
-
MEM
1 stop4h 15m
Multiple Airlines
Deal found 1/26$244

Find flight deals from Mississippi to South Carolina

Keep the following information in mind while searching for Mississippi to South Carolina flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$171
(Kiwi.com)

One-way from

$78
(Priceline)
Provider with most accurate pricing for Jackson-Evers Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Myrtle Beach Intl flights.
Search Deals
From Mississippi to South Carolina
Search Deals
One-way flight from Mississippi to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Mississippi to South Carolina that are best for you.

Fly from

Mississippi

Fly to

South Carolina

Route

Depart

Return

Price

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Thu 2/26

7:04 pm-2:20 pm

2 stops18h 16m

Charlotte Douglas

Tue 3/3

2:46 pm-10:20 am

1 stop20h 34m

$190

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Wed 2/25

11:15 am-7:58 am

1 stop19h 43m

Charlotte Douglas

Sun 3/1

9:52 pm-10:20 am

1 stop13h 28m

$191

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Sat 2/14

11:15 am-10:17 am

1 stop22h 02m

Charlotte Douglas

Mon 2/16

10:42 pm-10:20 am

1 stop12h 38m

$200

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Wed 2/11

11:44 am-8:13 am

1 stop19h 29m

Charlotte Douglas

Mon 2/16

10:42 pm-10:20 am

1 stop12h 38m

$207

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Thu 2/12

7:04 pm-2:18 pm

2 stops18h 14m

Charlotte Douglas

Fri 2/20

10:20 pm-10:20 am

1 stop13h 00m

$210

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Thu 2/26

11:15 am-7:58 am

1 stop19h 43m

Charlotte Douglas

Sun 3/1

9:52 pm-10:20 am

1 stop13h 28m

$211

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Fri 2/27

11:15 am-8:33 am

1 stop20h 18m

Charlotte Douglas

Sun 3/1

5:55 am-6:19 pm

2 stops13h 24m

$220

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Fri 2/13

11:15 am-8:33 am

1 stop20h 18m

Charlotte Douglas

Wed 2/18

7:13 pm-6:15 pm

1 stop24h 02m

$228

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Thu 4/9

11:14 am-7:48 pm

1 stop7h 34m

Charlotte Douglas

Sun 4/12

2:47 pm-10:15 am

1 stop20h 28m

$240

MemphisMyrtle Beach

MEM - MYR

MEMMYR

Memphis

Thu 4/2

8:30 pm-5:39 pm

1 stop20h 09m

Myrtle Beach Intl

Sun 4/5

6:37 pm-8:02 am

1 stop14h 25m

$245

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South Carolina

What is the cheapest month to book a flight from Mississippi to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Mississippi to South Carolina (average of $191). Flying from Mississippi to South Carolina in December is currently the most expensive (average of $388). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Mississippi to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 28, 2026.
See what other customers who have flown with Delta and American Airlines from Mississippi to South Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,123 reviews

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,123 reviews
Delta
7.9
Good
8,123 reviews

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,201 reviews
Delta
7.9
Good
8,123 reviews

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to South Carolina?

    Departing from Mississippi to South Carolina will take you 4h 56m. The distance between Mississippi and South Carolina is about 672 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Mississippi to South Carolina that include hotel bookings?

    Yes. In addition to deals on Mississippi to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South Carolina.

  • Can I find deals for business class flights from Mississippi to South Carolina?

    Yes. Cheapflights offers flight deals from Mississippi to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to South Carolina (average of $191). Flying from Mississippi to South Carolina in December is currently the most expensive (average of $388). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to South Carolina

Discover the top 2 airlines that operate flights from Mississippi to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$191Average$362FlexibilityNo cancel feeOn-time71%
DeltaCheapest$193Average$405FlexibilityNo cancel feeOn-timeN/A

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