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South Carolina

$97+ Cheap flights from Mississippi to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — CHS
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Mississippi to South Carolina

Keep the following information in mind while searching for Mississippi to South Carolina flight deals. Data was last updated September 15, 2025.

Round-trip from

$200
(American Airlines)

One-way from

$97
(Cheapflightsfares)
From Mississippi to South Carolina
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One-way flight from Mississippi to South Carolina
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Find flight deals from Mississippi to South Carolina

Cheapest flights from Mississippi to South Carolina
Explore the most affordable flight options available from Mississippi to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/410:54 amMEM - CLT
1 stop8h 43mAmerican Airlines
Sat 10/410:06 pmCLT - MEM
Nonstop1h 53mAmerican Airlines
Deal found 9/13$200
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/58:20 pmMEM - CLT
1 stop15h 00mMultiple Airlines
Wed 10/85:45 amCLT - MEM
1 stop26h 57mMultiple Airlines
Deal found 9/13$202
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/268:40 pmMEM - CLT
1 stop14h 40mMultiple Airlines
Thu 10/3010:06 pmCLT - MEM
1 stop22h 13mMultiple Airlines
Deal found 9/12$204
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/167:11 pmMEM - CLT
1 stop13h 04mMultiple Airlines
Mon 10/2010:06 pmCLT - MEM
1 stop22h 39mMultiple Airlines
Deal found 9/14$212
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/28:30 pmMEM - CLT
1 stop14h 13mMultiple Airlines
Mon 10/610:06 pmCLT - MEM
1 stop22h 39mMultiple Airlines
Deal found 9/13$216
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/297:00 amMEM - CLT
1 stop23h 47mMultiple Airlines
Wed 11/59:49 amCLT - MEM
1 stop22h 43mMultiple Airlines
Deal found 9/15$223
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/288:43 amMEM - CHS
1 stop23h 22mMultiple Airlines
Wed 10/18:10 pmCHS - MEM
1 stop23h 21mMultiple Airlines
Deal found 9/14$226
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/187:00 amMEM - CLT
1 stop5h 52mSpirit Airlines
Sat 10/2510:06 pmCLT - MEM
1 stop26h 02mSpirit Airlines
Deal found 9/13$230
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/114:19 pmMEM - CHS
1 stop15h 38mMultiple Airlines
Sat 12/138:10 pmCHS - MEM
1 stop23h 21mMultiple Airlines
Deal found 9/13$230
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/307:00 amMEM - CLT
1 stop4h 53mSpirit Airlines
Sat 10/41:53 pmCLT - MEM
1 stop10h 57mSpirit Airlines
Deal found 9/13$232
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/297:55 pmMEM - CHS
1 stop11h 42mMultiple Airlines
Wed 10/18:10 pmCHS - MEM
1 stop23h 21mMultiple Airlines
Deal found 9/14$234
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:11 pmMEM - CLT
1 stop17h 10mMultiple Airlines
Sat 12/139:49 amCLT - MEM
1 stop8h 33mMultiple Airlines
Deal found 9/15$235

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Mississippi to South Carolina that are best for you.

Fly from

Mississippi

Fly to

South Carolina

Route

Depart

Return

Price

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Sat 10/4

10:54 am-8:37 pm

1 stop8h 43m

Charlotte Douglas

Sat 10/4

10:06 pm-10:59 pm

Nonstop1h 53m

$200

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Sun 10/5

8:20 pm-12:20 pm

1 stop15h 00m

Charlotte Douglas

Wed 10/8

5:45 am-7:42 am

1 stop26h 57m

$202

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Thu 10/23

7:11 pm-12:20 pm

1 stop16h 09m

Charlotte Douglas

Sun 10/26

10:06 pm-11:08 pm

1 stop26h 02m

$212

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Thu 10/16

7:11 pm-9:15 am

1 stop13h 04m

Charlotte Douglas

Mon 10/20

10:06 pm-7:45 pm

1 stop22h 39m

$212

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Sat 10/18

7:00 am-1:52 pm

1 stop5h 52m

Charlotte Douglas

Sat 10/25

10:06 pm-11:08 pm

1 stop26h 02m

$230

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Mon 9/29

7:55 pm-8:37 am

1 stop11h 42m

Charleston

Wed 10/1

8:10 pm-6:31 pm

1 stop23h 21m

$234

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Thu 12/11

7:11 pm-1:21 pm

1 stop17h 10m

Charlotte Douglas

Sat 12/13

9:49 am-5:22 pm

1 stop8h 33m

$235

MemphisSavannah

MEM - SAV

MEMSAV

Memphis

Thu 12/11

6:23 am-12:31 pm

1 stop5h 08m

Savannah/Hilton Head

Sat 12/13

11:12 am-9:21 pm

1 stop11h 09m

$246

MemphisSavannah

MEM - SAV

MEMSAV

Memphis

Mon 3/2

2:43 pm-9:38 pm

1 stop5h 55m

Savannah/Hilton Head

Wed 3/4

7:41 am-4:30 pm

1 stop9h 49m

$246

MemphisGreenville

MEM - GSP

MEMGSP

Memphis

Sat 10/25

6:56 pm-11:51 pm

1 stop3h 55m

Greenville

Tue 10/28

6:00 am-9:29 am

1 stop4h 29m

$247

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South Carolina

What is the cheapest month to book a flight from Mississippi to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Mississippi to South Carolina (average of $217). Flying from Mississippi to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to SC?

Find hourly flight availability from Mississippi to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to South Carolina as you normally would.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 15, 2025.
See what other customers who have flown with Southwest, Delta, and American Airlines from Mississippi to South Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,954 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to South Carolina?

    Departing from Mississippi to South Carolina will take you 5h 52m. The distance between Mississippi and South Carolina is about 510 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Mississippi to South Carolina one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $97. Users have also found prices from $119 and $119 on Delta and United Airlines, respectively.

  • Can I find deals for flights from Mississippi to South Carolina that include hotel bookings?

    Yes. In addition to deals on Mississippi to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South Carolina.

  • Can I find deals for business class flights from Mississippi to South Carolina?

    Yes. Cheapflights offers flight deals from Mississippi to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to South Carolina (average of $217). Flying from Mississippi to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Mississippi to South Carolina

Discover the top 3 airlines that operate flights from Mississippi to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$191Average$434FlexibilityNo cancel feeOn-time71%
DeltaCheapest$196Average$416FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$260Average$376FlexibilityNo cancel feeOn-time63%

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