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South Carolina

$85+ Cheap flights from Mississippi to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — CHS
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from Mississippi to South Carolina

Keep the following information in mind while searching for Mississippi to South Carolina flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$196
(Kiwi.com)

One-way from

$85
(Breeze Airways)
Provider with most accurate pricing for Jackson-Evers Intl-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Myrtle Beach Intl flights.
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From Mississippi to South Carolina
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One-way flight from Mississippi to South Carolina
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Find flight deals from Mississippi to South Carolina

Cheapest flights from Mississippi to South Carolina
Explore the most affordable flight options available from Mississippi to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:07 pmMEM - CLT
1 stop19h 42mMultiple Airlines
Mon 12/82:58 pmCLT - MEM
1 stop22h 34mMultiple Airlines
Deal found 10/28$196
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:42 pmMEM - CLT
1 stop12h 55mMultiple Airlines
Sun 12/78:44 amCLT - MEM
1 stop11h 52mMultiple Airlines
Deal found 10/30$203
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2610:07 amMEM - CLT
1 stop6h 05mMultiple Airlines
Tue 12/210:45 amCLT - MEM
1 stop23h 17mMultiple Airlines
Deal found 10/30$208
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:42 pmMEM - CLT
1 stop11h 15mMultiple Airlines
Mon 12/152:58 pmCLT - MEM
1 stop22h 34mMultiple Airlines
Deal found 10/30$209
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:42 pmMEM - CLT
1 stop23h 18mMultiple Airlines
Tue 12/910:45 amCLT - MEM
1 stop9h 02mMultiple Airlines
Deal found 10/30$212
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/75:14 pmMEM - CHS
1 stop26h 40mMultiple Airlines
Fri 12/129:49 pmCHS - MEM
2 stops21h 58mMultiple Airlines
Deal found 10/29$213
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:42 pmMEM - CLT
1 stop11h 15mMultiple Airlines
Sun 12/148:44 amCLT - MEM
1 stop10h 47mMultiple Airlines
Deal found 10/29$219
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/75:14 pmMEM - CHS
1 stop26h 40mMultiple Airlines
Sat 12/1311:55 amCHS - MEM
2 stops32h 17mMultiple Airlines
Deal found 10/29$220
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/33:47 pmMEM - CLT
1 stop20h 45mMultiple Airlines
Thu 12/48:55 amCLT - MEM
1 stop8h 41mMultiple Airlines
Deal found 10/28$222
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/67:42 pmMEM - CHS
1 stop11h 55mMultiple Airlines
Thu 12/119:38 pmCHS - MEM
2 stops14h 52mMultiple Airlines
Deal found 10/30$223
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/148:55 pmMEM - CLT
1 stop14h 28mMultiple Airlines
Tue 11/187:25 pmCLT - MEM
2 stops39h 38mMultiple Airlines
Deal found 10/30$233
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:42 pmMEM - MYR
1 stop16h 38mSpirit Airlines
Sun 12/148:27 pmMYR - MEM
1 stop23h 20mSpirit Airlines
Deal found 10/30$238

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Mississippi to South Carolina that are best for you.

Fly from

Mississippi

Fly to

South Carolina

Route

Depart

Return

Price

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Sun 12/7

5:14 pm-8:54 pm

1 stop26h 40m

Charleston

Fri 12/12

9:49 pm-6:47 pm

2 stops21h 58m

$213

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Sat 12/6

7:42 pm-8:37 am

1 stop11h 55m

Charleston

Thu 12/11

9:38 pm-11:30 am

2 stops14h 52m

$223

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Sun 12/7

5:14 pm-8:54 pm

1 stop26h 40m

Charleston

Sat 12/13

8:10 pm-7:36 pm

1 stop24h 26m

$227

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Sun 11/2

8:20 pm-5:36 pm

1 stop20h 16m

Charlotte Douglas

Sun 11/9

6:20 pm-7:22 pm

1 stop26h 02m

$240

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Sat 12/6

7:42 pm-8:54 pm

2 stops24h 12m

Charleston

Thu 12/11

9:49 pm-6:47 pm

2 stops21h 58m

$243

Baton RougeGreenville

BTR - GSP

BTRGSP

Baton Rouge Ryan

Wed 3/25

1:40 pm-6:49 pm

1 stop4h 09m

Greenville

Sat 3/28

7:45 am-12:54 pm

1 stop6h 09m

$249

Baton RougeCharleston

BTR - CHS

BTRCHS

Baton Rouge Ryan

Thu 12/18

6:59 pm-11:50 pm

1 stop3h 51m

Charleston

Fri 12/26

5:30 am-9:49 am

1 stop5h 19m

$249

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Sun 12/7

7:42 pm-8:54 pm

2 stops24h 12m

Charleston

Fri 12/12

9:49 pm-6:47 pm

2 stops21h 58m

$249

Baton RougeCharleston

BTR - CHS

BTRCHS

Baton Rouge Ryan

Thu 12/4

10:32 am-5:24 pm

1 stop5h 52m

Charleston

Sun 12/7

5:25 am-9:43 am

1 stop5h 18m

$249

Baton RougeCharleston

BTR - CHS

BTRCHS

Baton Rouge Ryan

Sat 3/7

1:40 pm-7:09 pm

1 stop4h 29m

Charleston

Wed 3/11

6:30 am-9:44 am

1 stop4h 14m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South Carolina

What is the cheapest month to book a flight from Mississippi to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Mississippi to South Carolina (average of $191). Flying from Mississippi to South Carolina in July is currently the most expensive (average of $273). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to SC?

Find hourly flight availability from Mississippi to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

A simple way to save on the total cost of your ticket is to fly from Mississippi to South Carolina at noon. If you’re flexible enough to do this you can expect to save up to 24% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 30, 2025.
See what other customers who have flown with Delta and American Airlines from Mississippi to South Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,035 reviews
Delta
7.9
Good
7,998 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to South Carolina?

    Departing from Mississippi to South Carolina will take you 4h 09m. The distance between Mississippi and South Carolina is about 600 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Mississippi to South Carolina one-way?

    For one-way options, check prices for Breeze Airways. According to our data, you can fly for as low as $85. Users have also found prices from $119 and $125 on Spirit Airlines and American Airlines, respectively.

  • Can I find deals for flights from Mississippi to South Carolina that include hotel bookings?

    Yes. In addition to deals on Mississippi to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South Carolina.

  • Can I find deals for business class flights from Mississippi to South Carolina?

    Yes. Cheapflights offers flight deals from Mississippi to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to South Carolina (average of $191). Flying from Mississippi to South Carolina in July is currently the most expensive (average of $273). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to South Carolina

Discover the top 2 airlines that operate flights from Mississippi to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$191Average$382FlexibilityNo cancel feeOn-time71%
DeltaCheapest$193Average$405FlexibilityNo cancel feeOn-timeN/A

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