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South Carolina

$67+ Cheap flights from Mississippi to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — CHS
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Mississippi to South Carolina

Keep the following information in mind while searching for Mississippi to South Carolina flight deals. Data was last updated July 31, 2025.

Round-trip from

$140
(Mytrip)

One-way from

$67
(Booking.com)
From Mississippi to South Carolina
Search Deals
One-way flight from Mississippi to South Carolina
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Find flight deals from Mississippi to South Carolina

Cheapest flights from Mississippi to South Carolina
Explore the most affordable flight options available from Mississippi to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/27:00 amMEM - CAE
1 stop10h 16mSpirit Airlines
Sun 10/57:11 pmCAE - MEM
1 stop5h 39mSpirit Airlines
Deal found 7/30$140
This Booking.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/48:35 pmMEM - CLT
1 stop10h 30mSpirit Airlines
Mon 9/86:11 amCLT - MEM
1 stop7h 19mSpirit Airlines
Deal found 7/29$152
This Mytrip deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/288:35 pmMEM - MYR
1 stop14h 22mSpirit Airlines
Wed 10/14:15 pmMYR - MEM
1 stop8h 35mSpirit Airlines
Deal found 7/31$167
This Mytrip deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2110:37 amMEM - CHS
1 stop7h 35mMultiple Airlines
Sun 8/2410:38 amCHS - MEM
1 stop6h 26mMultiple Airlines
Deal found 7/31$213
This Mytrip deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/258:43 amMEM - CLT
1 stop5h 49mMultiple Airlines
Mon 9/292:58 pmCLT - MEM
2 stops9h 52mMultiple Airlines
Deal found 7/31$222
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/227:46 pmMEM - MYR
2 stops14h 15mMultiple Airlines
Mon 8/259:40 pmMYR - MEM
2 stops25h 54mMultiple Airlines
Deal found 7/30$224
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/16:45 amMEM - CLT
1 stop3h 16mDelta
Thu 9/411:21 amCLT - MEM
1 stop5h 30mDelta
Deal found 7/31$227
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/276:40 pmJAN - CLT
1 stop16h 37mAmerican Airlines
Thu 8/282:35 pmCLT - JAN
Nonstop2h 05mAmerican Airlines
Deal found 7/31$228
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/266:55 amMEM - CHS
1 stop6h 13mAmerican Airlines
Tue 9/27:38 pmCHS - MEM
1 stop4h 22mAmerican Airlines
Deal found 7/31$236
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/122:21 pmMEM - SAV
1 stop4h 07mDelta
Tue 9/1610:22 amSAV - MEM
1 stop6h 16mDelta
Deal found 7/31$237
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/312:46 pmMEM - MYR
1 stop4h 25mDelta
Sat 9/66:35 pmMYR - MEM
1 stop5h 18mDelta
Deal found 7/31$237
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/56:50 pmJAN - CHS
1 stop4h 01mDelta
Sun 9/75:15 amCHS - JAN
1 stop4h 58mDelta
Deal found 7/31$237

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Mississippi to South Carolina that are best for you.

Fly from

Mississippi

Fly to

South Carolina

Route

Depart

Return

Price

MemphisColumbia

MEM - CAE

MEMCAE

Memphis

Thu 10/2

7:00 am-6:16 pm

1 stop10h 16m

Columbia Metropolitan

Sun 10/5

7:11 pm-11:50 pm

1 stop5h 39m

$140

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Thu 9/4

8:35 pm-8:05 am

1 stop10h 30m

Charlotte Douglas

Mon 9/8

6:11 am-12:30 pm

1 stop7h 19m

$152

MemphisMyrtle Beach

MEM - MYR

MEMMYR

Memphis

Sun 9/28

8:35 pm-11:57 am

1 stop14h 22m

Myrtle Beach Intl

Wed 10/1

4:15 pm-11:50 pm

1 stop8h 35m

$167

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Thu 8/21

10:37 am-7:12 pm

1 stop7h 35m

Charleston

Sun 8/24

10:38 am-4:04 pm

1 stop6h 26m

$213

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Thu 9/25

8:43 am-3:32 pm

1 stop5h 49m

Charlotte Douglas

Mon 9/29

2:58 pm-11:50 pm

2 stops9h 52m

$222

MemphisMyrtle Beach

MEM - MYR

MEMMYR

Memphis

Fri 8/22

7:46 pm-11:01 am

2 stops14h 15m

Myrtle Beach Intl

Mon 8/25

9:40 pm-10:34 pm

2 stops25h 54m

$224

MemphisCharlotte

MEM - CLT

MEMCLT

Memphis

Mon 9/1

6:45 am-11:01 am

1 stop3h 16m

Charlotte Douglas

Thu 9/4

11:21 am-3:51 pm

1 stop5h 30m

$227

JacksonCharlotte

JAN - CLT

JANCLT

Jackson-Evers Intl

Wed 8/27

6:40 pm-12:17 pm

1 stop16h 37m

Charlotte Douglas

Thu 8/28

2:35 pm-3:40 pm

Nonstop2h 05m

$228

MemphisCharleston

MEM - CHS

MEMCHS

Memphis

Tue 8/26

6:55 am-2:08 pm

1 stop6h 13m

Charleston

Tue 9/2

7:38 pm-11:00 pm

1 stop4h 22m

$236

MemphisSavannah

MEM - SAV

MEMSAV

Memphis

Fri 9/12

2:21 pm-7:28 pm

1 stop4h 07m

Savannah/Hilton Head

Tue 9/16

10:22 am-3:38 pm

1 stop6h 16m

$237

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South Carolina

What is the cheapest month to book a flight from Mississippi to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Mississippi to South Carolina (average of $217). Flying from Mississippi to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to SC?

Find hourly flight availability from Mississippi to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to South Carolina as you normally would.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 31, 2025.
See what other customers who have flown with Southwest, Delta, and Breeze Airways from Mississippi to South Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,981 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Breeze Airways
8.0
Very good
191 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,900 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Mississippi to South Carolina one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $67. Users have also found prices from $114 and $118 on Delta and Allegiant Air, respectively.

  • Can I find deals for flights from Mississippi to South Carolina that include hotel bookings?

    Yes. In addition to deals on Mississippi to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South Carolina.

  • Can I find deals for business class flights from Mississippi to South Carolina?

    Yes. Cheapflights offers flight deals from Mississippi to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to South Carolina (average of $217). Flying from Mississippi to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Mississippi to South Carolina

Discover the top 3 airlines that operate flights from Mississippi to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$191Average$373FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$409FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$260Average$376FlexibilityNo cancel feeOn-time63%

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