$34+ Cheap flights from Massachusetts to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
BOS — CHS
Feb 28 — Mar 71
1 adult, Economy
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Massachusetts to South Carolina
Cheapest flights from Massachusetts to South CarolinaExplore the most affordable flight options available from Massachusetts to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.
Explore the most affordable flight options available from Massachusetts to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/29:57 am
BOS
- MYR
Nonstop2h 28m
Spirit Airlines
Tue 3/101:20 pm
MYR
- BOS
Nonstop2h 07m
Spirit Airlines
Deal found 1/28![Spirit Airlines logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/259:57 am
BOS
- MYR
Nonstop2h 28m
Spirit Airlines
Tue 3/31:20 pm
MYR
- BOS
Nonstop2h 07m
Spirit Airlines
Deal found 1/27![Spirit Airlines logo]()
$97
This Super.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/226:29 pm
BOS
- MYR
Nonstop2h 19m
Spirit Airlines
Wed 3/256:37 pm
MYR
- BOS
1 stop5h 22m
Spirit Airlines
Deal found 1/27![Spirit Airlines logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/189:57 am
BOS
- MYR
Nonstop2h 28m
Spirit Airlines
Thu 2/261:20 pm
MYR
- BOS
Nonstop2h 07m
Spirit Airlines
Deal found 1/28![Spirit Airlines logo]()
$101
This Cheapflightsfares deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/239:57 am
BOS
- MYR
Nonstop2h 28m
Spirit Airlines
Mon 3/21:20 pm
MYR
- BOS
Nonstop2h 07m
Spirit Airlines
Deal found 1/28![Spirit Airlines logo]()
$102
This Priceline deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:39 pm
BOS
- MYR
Nonstop2h 25m
Spirit Airlines
Sat 2/149:53 am
MYR
- BOS
Nonstop1h 59m
Spirit Airlines
Deal found 1/28![Spirit Airlines logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/92:37 pm
BDL
- CHS
Nonstop2h 28m
Breeze Airways
Wed 2/1111:42 am
CHS
- BDL
Nonstop2h 05m
Breeze Airways
Deal found 1/27![Breeze Airways logo]()
$103
This Cheapflightsfares deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/279:57 am
BOS
- MYR
Nonstop2h 28m
Spirit Airlines
Fri 3/61:20 pm
MYR
- BOS
Nonstop2h 07m
Spirit Airlines
Deal found 1/28![Spirit Airlines logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/179:57 am
BOS
- MYR
Nonstop2h 28m
Spirit Airlines
Wed 2/251:20 pm
MYR
- BOS
Nonstop2h 07m
Spirit Airlines
Deal found 1/28![Spirit Airlines logo]()
$106
This CheapOair deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/279:57 am
BOS
- MYR
Nonstop2h 28m
Spirit Airlines
Mon 3/21:20 pm
MYR
- BOS
Nonstop2h 07m
Spirit Airlines
Deal found 1/28![Spirit Airlines logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/19:57 am
BOS
- MYR
Nonstop2h 28m
Spirit Airlines
Thu 3/126:37 pm
MYR
- BOS
1 stop5h 22m
Spirit Airlines
Deal found 1/28![Spirit Airlines logo]()
$109
This CheapOair deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:29 pm
BOS
- MYR
Nonstop2h 19m
Spirit Airlines
Sat 4/1810:37 am
MYR
- BOS
Nonstop2h 05m
Spirit Airlines
Deal found 1/27![Spirit Airlines logo]()
$110
Find flight deals from Massachusetts to South Carolina
Keep the following information in mind while searching for Massachusetts to South Carolina flight deals. Data was last updated January 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $96 (Kiwi.com) |
One-way from | $34 (Priceline) |
Popular in | December |
Cheapest in | February |
Average price | $167 |
Good round-trip deal | $138 or less |
Good one-way deal | $85 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Massachusetts to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Massachusetts to South Carolina that are best for you.
Fly from
Massachusetts
Fly to
South Carolina
Route
Depart
Return
Price
BostonMyrtle Beach
BOS - MYR
BOSMYR
Boston Logan Intl
Wed 4/8
5:40 am-5:39 pm
1 stop11h 59m
Myrtle Beach Intl
Mon 4/13
3:29 pm-5:33 pm
Nonstop2h 04m
$98
BostonMyrtle Beach
BOS - MYR
BOSMYR
Boston Logan Intl
Sat 3/7
6:10 pm-7:13 am
1 stop13h 03m
Myrtle Beach Intl
Fri 3/13
3:29 pm-5:33 pm
Nonstop2h 04m
$103
HartfordCharleston
BDL - CHS
BDLCHS
Hartford Bradley Intl
Mon 3/23
2:37 pm-5:05 pm
Nonstop2h 28m
Charleston
Thu 3/26
7:56 pm-10:01 pm
Nonstop2h 05m
$123
BostonMyrtle Beach
BOS - MYR
BOSMYR
Boston Logan Intl
Wed 2/18
6:00 am-8:39 pm
2 stops14h 39m
Myrtle Beach Intl
Wed 2/25
1:20 pm-3:27 pm
Nonstop2h 07m
$143
BostonMyrtle Beach
BOS - MYR
BOSMYR
Boston Logan Intl
Tue 3/10
9:57 am-12:25 pm
Nonstop2h 28m
Myrtle Beach Intl
Fri 3/13
6:37 pm-11:59 pm
1 stop5h 22m
$146
HartfordCharleston
BDL - CHS
BDLCHS
Hartford Bradley Intl
Sat 5/9
6:10 am-8:28 am
Nonstop2h 18m
Charleston
Sat 5/16
9:04 pm-11:12 pm
Nonstop2h 08m
$148
BostonMyrtle Beach
BOS - MYR
BOSMYR
Boston Logan Intl
Sun 4/19
6:33 pm-9:03 pm
Nonstop2h 30m
Myrtle Beach Intl
Thu 4/23
8:01 pm-10:04 pm
Nonstop2h 03m
$148
BostonSavannah
BOS - SAV
BOSSAV
Boston Logan Intl
Wed 3/4
1:20 pm-8:15 pm
1 stop6h 55m
Savannah/Hilton Head
Mon 3/9
7:45 pm-12:05 am
1 stop4h 20m
$151
BostonSavannah
BOS - SAV
BOSSAV
Boston Logan Intl
Tue 3/3
1:20 pm-8:15 pm
1 stop6h 55m
Savannah/Hilton Head
Mon 3/9
7:45 pm-12:05 am
1 stop4h 20m
$151
BostonSavannah
BOS - SAV
BOSSAV
Boston Logan Intl
Mon 3/2
2:45 pm-8:50 pm
1 stop6h 05m
Savannah/Hilton Head
Sat 3/7
2:15 pm-11:05 pm
1 stop8h 50m
$156
Showing 1-10 of 60 results
Best time to book a flight from Massachusetts to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Massachusetts with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Massachusetts to South Carolina
What is the cheapest month to book a flight from Massachusetts to South Carolina?
Currently, March is the cheapest month in which you can book a flight from Massachusetts to South Carolina (average of $63). Flying from Massachusetts to South Carolina in October is currently the most expensive (average of $108). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MA to SC?
Find hourly flight availability from Massachusetts to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.
It’s optimal to fly from Massachusetts to South Carolina in the evening. By choosing this option you can save up to 23% on the cost of your flight, compared to a flight at noon.
What is the cheapest day to fly from Massachusetts to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Massachusetts to South Carolina. Price data was last updated on January 24, 2026.
Travelers seeking maximum savings on their Massachusetts to South Carolina flight should consider departing on Monday evenings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Massachusetts to South Carolina
Explore weekly flight availability from Massachusetts to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 29, 2026.
The most flights from USMA to USSC are scheduled on a Thursday (5 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (2 on average).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 29, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Massachusetts to South Carolina by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Massachusetts to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Massachusetts to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Top 7 airlines flying from Massachusetts to South Carolina
Discover the top 7 airlines that operate flights from Massachusetts to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$41 | Average$183 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$55 | Average$175 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$85 | Average$325 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$86 | Average$264 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$133 | Average$358 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$173 | Average$378 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$181 | Average$392 | FlexibilityNo cancel fee | On-time63% |