How long is the flight from San Antonio to South America?

There are many flights that can get you from San Antonio to South America in 13h 17m. Fly via Spirit Airlines, United Airlines, or Delta to get the fastest option. The distance between San Antonio and South America is about 2336 mi. This flight may include one or multiple stops.

What are the cheapest airlines to fly from San Antonio to South America one-way?

The cheapest airlines for a one-way flight from San Antonio to South America are Delta ($162), United Airlines ($178), and American Airlines ($184).

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

What are the most popular routes from San Antonio to South America?

When deciding which route to take from San Antonio to South America consider San Antonio - Medellín Jose Maria Cordova Intl, San Antonio - Rio de Janeiro–Galeão Intl or San Antonio - Lima J Chavez Intl as they are the most popular.

What are the most popular airlines that fly from San Antonio to South America?

The most popular airlines flying from San Antonio to South America are United Airlines, American Airlines and Delta. Something to consider prior to booking your flight.

What is the cheapest time of day to fly from SAT to SA?

When flying from San Antonio to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What airport do you fly from for flights from San Antonio to South America?

Located just 7.6 mi from the city center, San Antonio (SAT) is the airport most travelers will use when flying to South America from San Antonio.

Can I find deals for flights from San Antonio to South America that include hotel bookings?

Yes. In addition to deals on San Antonio to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from San Antonio to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to South America.

Can I find deals for business class flights from San Antonio to South America?

Yes. Cheapflights offers flight deals from San Antonio to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$161+ Flights from San Antonio to South America

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from San Antonio to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Antonio to South America

Cheapest flights from San Antonio to South America
Explore the most affordable flight options available from San Antonio to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on décembre 28, 2025.

mar. 12/307:05 amSAT - BOG

1 stop11h 25mDelta

mer. 2/115:00 amBOG - SAT

2 stops20h 39mDelta

Deal found 12/26

$415

sam. 12/277:04 pmSAT - BOG

1 stop26h 31mUnited Airlines

mar. 4/78:30 amBOG - SAT

1 stop14h 29mUnited Airlines

Deal found 12/27

$446

lun. 12/295:15 amSAT - MDE

1 stop15h 50mUnited Airlines

mar. 12/301:15 amMDE - SAT

1 stop15h 38mUnited Airlines

Deal found 12/25

$513

lun. 12/296:37 amSAT - BOG

2 stops14h 33mAmerican Airlines

mar. 12/3011:55 pmBOG - SAT

1 stop10h 50mAmerican Airlines

Deal found 12/26

$544

ven. 12/262:39 pmSAT - BOG

1 stop9h 33mSpirit Airlines

ven. 1/91:45 pmBOG - SAT

1 stop11h 07mSpirit Airlines

Deal found 12/26

$712

dim. 12/282:39 pmSAT - BOG

1 stop9h 33mSpirit Airlines

sam. 1/101:45 pmBOG - SAT

1 stop11h 07mSpirit Airlines

Deal found 12/26

$741

lun. 12/2912:45 pmSAT - BOG

2 stops11h 27mSpirit Airlines

mar. 12/303:05 pmBOG - SAT

2 stops21h 45mSpirit Airlines

Deal found 12/26

$754

ven. 12/266:22 pmSAT - BOG

1 stop24h 08mDelta

ven. 1/95:00 amBOG - SAT

2 stops19h 23mDelta

Deal found 12/26

$774

lun. 12/297:37 pmSAT - LIM

2 stops15h 48mMultiple Airlines

lun. 1/126:04 amLIM - SAT

1 stop29h 07mMultiple Airlines

Deal found 12/26

$840

lun. 12/297:37 pmSAT - LIM

1 stop32h 13mVolaris

lun. 1/126:04 amLIM - SAT

1 stop29h 07mVolaris

Deal found 12/26

$882

lun. 12/297:37 pmSAT - LIM

2 stops15h 48mMultiple Airlines

dim. 1/116:04 amLIM - SAT

1 stop29h 07mMultiple Airlines

Deal found 12/26

$901

ven. 12/264:55 pmSAT - LIM

2 stops33h 35mMultiple Airlines

mar. 1/136:04 amLIM - SAT

1 stop10h 16mMultiple Airlines

Deal found 12/26

$909

Best flights from San Antonio to South America
Discover carefully curated flight deals from San Antonio to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated décembre 28, 2025.

lun. 2/910:35 amSAT - CLO

1 stop26h 40mSpirit Airlines

lun. 2/233:22 pmCLO - SAT

1 stop19h 08mSpirit Airlines

Deal found 12/26

$262

mer. 2/2510:26 amSAT - MDE

1 stop10h 14mMultiple Airlines

lun. 3/21:00 pmMDE - SAT

1 stop21h 30mMultiple Airlines

Deal found 12/27

$331

lun. 3/309:40 amSAT - CLO

2 stops32h 04mUnited Airlines

mar. 4/145:00 amCLO - SAT

2 stops27h 42mUnited Airlines

Deal found 12/26

$414

mer. 3/116:13 amSAT - BOG

1 stop13h 17mDelta

dim. 3/223:55 pmBOG - SAT

1 stop18h 00mDelta

Deal found 12/26

$415

dim. 1/255:20 amSAT - CTG

1 stop7h 57mLATAM Airlines

jeu. 1/293:32 pmCTG - SAT

1 stop10h 06mLATAM Airlines

Deal found 12/25

$418

jeu. 1/225:00 pmSAT - CTG

2 stops19h 30mAmerican Airlines

mar. 1/274:30 pmCTG - SAT

1 stop8h 29mAmerican Airlines

Deal found 12/27

$423

lun. 2/910:35 amSAT - CLO

1 stop26h 40mMultiple Airlines

lun. 2/1610:15 pmCLO - SAT

2 stops36h 15mMultiple Airlines

Deal found 12/26

$343

mar. 2/2410:26 amSAT - LIM

1 stop11h 09mSpirit Airlines

mer. 3/1810:30 pmLIM - SAT

1 stop10h 52mSpirit Airlines

Deal found 12/25

$365

lun. 2/2310:26 amSAT - MDE

1 stop10h 14mMultiple Airlines

jeu. 2/261:00 pmMDE - SAT

1 stop21h 30mMultiple Airlines

Deal found 12/26

$344

dim. 2/157:40 amSAT - CLO

2 stops9h 10mUnited Airlines

sam. 2/285:03 amCLO - SAT

2 stops28h 40mUnited Airlines

Deal found 12/26

$414

dim. 2/226:30 amSAT - BOG

2 stops19h 45mDelta

mer. 2/255:00 amBOG - SAT

2 stops20h 35mDelta

Deal found 12/26

$415

lun. 1/265:20 amSAT - CTG

1 stop7h 57mLATAM Airlines

jeu. 1/293:32 pmCTG - SAT

1 stop10h 06mLATAM Airlines

Deal found 12/26

$418

ven. 1/3010:35 amSAT - BOG

2 stops34h 56mMultiple Airlines

ven. 2/63:06 pmBOG - SAT

1 stop19h 24mMultiple Airlines

Deal found 12/26

$346

ven. 1/306:30 amSAT - BOG

1 stop29h 20mSpirit Airlines

mar. 2/31:45 pmBOG - SAT

2 stops44h 45mSpirit Airlines

Deal found 12/26

$389

lun. 2/211:43 amSAT - CLO

2 stops29h 07mUnited Airlines

jeu. 2/55:03 amCLO - SAT

2 stops18h 54mUnited Airlines

Deal found 12/27

$414

ven. 3/135:10 amSAT - BOG

1 stop9h 15mDelta

lun. 3/233:55 pmBOG - SAT

1 stop19h 34mDelta

Deal found 12/26

$415

mer. 3/116:13 amSAT - CTG

1 stop7h 02mLATAM Airlines

ven. 3/202:30 pmCTG - SAT

1 stop10h 08mLATAM Airlines

Deal found 12/26

$418

sam. 1/1710:35 amSAT - LIM

1 stop11h 00mSpirit Airlines

dim. 1/2511:33 pmLIM - SAT

1 stop11h 07mSpirit Airlines

Deal found 12/26

$390

lun. 1/1910:35 amSAT - MDE

1 stop10h 05mMultiple Airlines

ven. 1/231:00 pmMDE - SAT

1 stop21h 40mMultiple Airlines

Deal found 12/26

$357

lun. 2/98:00 amSAT - BOG

1 stop10h 30mDelta

lun. 2/169:00 amBOG - SAT

1 stop12h 25mDelta

Deal found 12/25

$415

sam. 1/174:04 pmSAT - CLO

2 stops48h 33mUnited Airlines

sam. 2/143:11 pmCLO - SAT

2 stops42h 32mUnited Airlines

Deal found 12/27

$420

sam. 4/185:29 amSAT - MDE

1 stop7h 11mAmerican Airlines

sam. 4/255:50 amMDE - SAT

1 stop17h 17mAmerican Airlines

Deal found 12/27

$513

dim. 3/156:13 amSAT - CTG

1 stop7h 02mLATAM Airlines

sam. 3/212:30 pmCTG - SAT

1 stop19h 25mLATAM Airlines

Deal found 12/26

$427

mer. 2/186:00 amSAT - LIM

2 stops15h 35mSpirit Airlines

mer. 3/1810:30 pmLIM - SAT

1 stop10h 52mSpirit Airlines

Deal found 12/25

$411

jeu. 3/126:13 amSAT - BOG

1 stop8h 12mDelta

lun. 3/233:55 pmBOG - SAT

1 stop18h 00mDelta

Deal found 12/26

$415

jeu. 1/229:50 amSAT - CTG

2 stops12h 10mUnited Airlines

mar. 1/276:24 amCTG - SAT

2 stops17h 33mUnited Airlines

Deal found 12/26

$421

lun. 1/265:10 amSAT - MDE

1 stop7h 53mAmerican Airlines

lun. 2/27:00 amMDE - SAT

1 stop10h 30mAmerican Airlines

Deal found 12/27

$513

mar. 1/208:00 amSAT - BOG

1 stop10h 30mDelta

mar. 2/39:00 amBOG - SAT

1 stop14h 28mDelta

Deal found 12/27

$415

lun. 2/2310:26 amSAT - LIM

1 stop11h 09mSpirit Airlines

mer. 3/1810:30 pmLIM - SAT

1 stop10h 52mSpirit Airlines

Deal found 12/27

$415

lun. 1/267:29 amSAT - CTG

2 stops14h 31mUnited Airlines

jeu. 1/296:24 amCTG - SAT

2 stops12h 09mUnited Airlines

Deal found 12/26

$421

Last-minute flights from San Antonio to South America
Discover last-minute flight deals from San Antonio to South America. Data last updated décembre 28, 2025 and is based on user searches.

mar. 12/307:05 amSAT - BOG

1 stop11h 25mDelta

mer. 2/115:00 amBOG - SAT

2 stops20h 39mDelta

Deal found 12/26

$415

sam. 1/1710:35 amSAT - LIM

1 stop11h 00mSpirit Airlines

dim. 1/2511:33 pmLIM - SAT

1 stop11h 07mSpirit Airlines

Deal found 12/27

$390

sam. 1/174:04 pmSAT - CLO

2 stops48h 33mUnited Airlines

sam. 2/143:11 pmCLO - SAT

2 stops42h 32mUnited Airlines

Deal found 12/27

$420

lun. 1/1910:35 amSAT - MDE

1 stop10h 05mMultiple Airlines

ven. 1/231:00 pmMDE - SAT

1 stop21h 40mMultiple Airlines

Deal found 12/26

$357

jeu. 1/229:50 amSAT - CTG

2 stops12h 10mUnited Airlines

mar. 1/276:24 amCTG - SAT

2 stops17h 33mUnited Airlines

Deal found 12/26

$421

jeu. 1/225:00 pmSAT - CTG

2 stops19h 30mAmerican Airlines

mar. 1/274:30 pmCTG - SAT

1 stop8h 29mAmerican Airlines

Deal found 12/27

$423

dim. 1/255:20 amSAT - CTG

1 stop7h 57mLATAM Airlines

jeu. 1/293:32 pmCTG - SAT

1 stop10h 06mLATAM Airlines

Deal found 12/25

$418

lun. 1/2610:35 amSAT - LIM

1 stop11h 00mSpirit Airlines

lun. 2/211:33 pmLIM - SAT

2 stops25h 19mSpirit Airlines

Deal found 12/27

$386

lun. 1/2610:35 amSAT - MDE

1 stop26h 40mSpirit Airlines

lun. 2/22:50 pmMDE - SAT

1 stop10h 02mSpirit Airlines

Deal found 12/27

$415

ven. 1/3010:35 amSAT - BOG

2 stops34h 56mMultiple Airlines

ven. 2/63:06 pmBOG - SAT

1 stop19h 24mMultiple Airlines

Deal found 12/26

$346

ven. 1/306:30 amSAT - BOG

1 stop29h 20mSpirit Airlines

mar. 2/31:45 pmBOG - SAT

2 stops44h 45mSpirit Airlines

Deal found 12/26

$389

ven. 1/3010:35 amSAT - BOG

1 stop26h 32mSpirit Airlines

ven. 2/63:06 pmBOG - SAT

1 stop19h 24mSpirit Airlines

Deal found 12/26

$395

One-way flights from San Antonio to South America
Search for one-way flight options from San Antonio to South America. Find affordable one-way fares based on user searches. Data last updated décembre 28, 2025.

sam. 1/2410:35 amSAT - LIM

1 stop11h 00mSpirit Airlines

Deal found 12/25

$161

mar. 3/3110:26 amSAT - MDE

1 stop14h 10mSpirit Airlines

Deal found 12/27

$176

sam. 3/212:20 pmSAT - BOG

1 stop8h 15mUnited Airlines

Deal found 12/27

$179

mar. 3/172:08 pmSAT - BOG

1 stop21h 33mMultiple Airlines

Deal found 12/27

$181

sam. 3/215:00 amSAT - BOG

2 stops11h 45mMultiple Airlines

Deal found 12/26

$184

lun. 1/55:20 amSAT - CTG

1 stop7h 57mDelta

Deal found 12/25

$184

sam. 3/215:05 pmSAT - BOG

2 stops27h 15mLATAM Airlines

Deal found 12/27

$189

sam. 1/3110:35 amSAT - LIM

1 stop11h 00mSpirit Airlines

Deal found 12/25

$191

sam. 3/77:00 pmSAT - CTG

2 stops27h 00mUnited Airlines

Deal found 12/26

$197

ven. 1/237:20 pmSAT - CLO

2 stops21h 17mUnited Airlines

Deal found 12/26

$197

jeu. 1/84:29 pmSAT - CTG

1 stop20h 48mDelta

Deal found 12/26

$198

ven. 1/2310:35 amSAT - CLO

1 stop26h 40mSpirit Airlines

Deal found 12/26

$209

Find flight deals from San Antonio to South America

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$262 (Kiwi.com)
One-way from	$161 (Cheapflightsfares)

Provider with most accurate pricing for San Antonio-Sao Paulo (SAO) flight deals.

Search Deals

Provider most trusted by Cheapflights users for San Antonio-Sao Paulo (SAO) flights.

Search Deals

From San Antonio to South America

Search Deals

One-way flight from San Antonio to South America

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Antonio to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San AntonioCali

SAT - CLO

SATCLO

San Antonio

lun. 2/9

10:35 am-2:15 pm

1 stop26h 40m

Cali Alfonso B. Aragon Intl

lun. 2/23

3:22 pm-9:30 am

1 stop19h 08m

$262

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

mer. 2/25

10:26 am-9:40 pm

1 stop10h 14m

Medellín Jose Maria Cordova Intl

lun. 3/2

1:00 pm-9:30 am

1 stop21h 30m

$331

San AntonioCali

SAT - CLO

SATCLO

San Antonio

lun. 2/9

10:35 am-2:15 pm

1 stop26h 40m

Cali Alfonso B. Aragon Intl

lun. 2/16

10:15 pm-9:30 am

2 stops36h 15m

$343

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

lun. 2/23

10:26 am-9:40 pm

1 stop10h 14m

Medellín Jose Maria Cordova Intl

jeu. 2/26

1:00 pm-9:30 am

1 stop21h 30m

$344

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

ven. 1/30

10:35 am-10:31 pm

2 stops34h 56m

Bogotá El Dorado

ven. 2/6

3:06 pm-9:30 am

1 stop19h 24m

$346

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

lun. 1/19

10:35 am-9:40 pm

1 stop10h 05m

Medellín Jose Maria Cordova Intl

ven. 1/23

1:00 pm-9:40 am

1 stop21h 40m

$357

San AntonioLima

SAT - LIM

SATLIM

San Antonio

mar. 2/24

10:26 am-10:35 pm

1 stop11h 09m

Lima J Chavez Intl

mer. 3/18

10:30 pm-9:22 am

1 stop10h 52m

$365

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

ven. 1/30

6:30 am-12:50 pm

1 stop29h 20m

Bogotá El Dorado

mar. 2/3

1:45 pm-9:30 am

2 stops44h 45m

$389

San AntonioLima

SAT - LIM

SATLIM

San Antonio

sam. 1/17

10:35 am-10:35 pm

1 stop11h 00m

Lima J Chavez Intl

dim. 1/25

11:33 pm-9:40 am

1 stop11h 07m

$390

San AntonioLima

SAT - LIM

SATLIM

San Antonio

mer. 2/18

6:00 am-10:35 pm

2 stops15h 35m

Lima J Chavez Intl

mer. 3/18

10:30 pm-9:22 am

1 stop10h 52m

$411

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/25

Showing 1-10 of 60 results

...

Best time to book a flight from San Antonio to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Antonio with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to South America

What is the cheapest month to book a flight from San Antonio to South America?

Currently, October is the cheapest month in which you can book a flight from San Antonio to South America (average of $103). Flying from San Antonio to South America in August is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Read through reviews of airlines operating flights from San Antonio to South America, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,015 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,015 reviews

Delta

7.9

Good

8,015 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

LATAM Airlines

7.5

Good

1,895 reviews

Delta

7.9

Good

8,015 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

United Airlines

7.4

Good

9,114 reviews

Delta

7.9

Good

8,015 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

American Airlines

7.2

Good

11,070 reviews

Delta

7.9

Good

8,015 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Spirit Airlines

6.3

Okay

8,209 reviews

Delta

7.9

Good

8,015 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

What airport do you fly from for flights from San Antonio to South America?
Located just 7.6 mi from the city center, San Antonio (SAT) is the airport most travelers will use when flying to South America from San Antonio.
How long is the flight from San Antonio to South America?
There are many flights that can get you from San Antonio to South America in 13h 17m. Fly via Spirit Airlines, United Airlines, or Delta to get the fastest option. The distance between San Antonio and South America is about 2336 mi. This flight may include one or multiple stops.
What are the cheapest airlines to fly from San Antonio to South America one-way?
The cheapest airlines for a one-way flight from San Antonio to South America are Delta ($162), United Airlines ($178), and American Airlines ($184).
What are the most popular routes from San Antonio to South America?
When deciding which route to take from San Antonio to South America consider San Antonio - Medellín Jose Maria Cordova Intl, San Antonio - Rio de Janeiro–Galeão Intl or San Antonio - Lima J Chavez Intl as they are the most popular.
Can I find deals for flights from San Antonio to South America that include hotel bookings?
Yes. In addition to deals on San Antonio to South America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from San Antonio to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to South America.
Can I find deals for business class flights from San Antonio to South America?
Yes. Cheapflights offers flight deals from San Antonio to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from San Antonio to South America?
Currently, October is the cheapest month in which you can book a flight from San Antonio to South America (average of $103). Flying from San Antonio to South America in August is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from San Antonio to South America

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$325	Average$577	FlexibilityNo cancel fee	On-time65%
American Airlines	Cheapest$401	Average$730	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$412	Average$717	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$414	Average$867	FlexibilityNo cancel fee	On-time69%
LATAM Airlines	Cheapest$539	Average$851	FlexibilityNo cancel fee	On-time81%
Aeromexico	Cheapest$648	Average$725	FlexibilityNo cancel fee	On-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$161+ Cheap flights from San Antonio (SAT) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/24. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from San Antonio to South America with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from San Antonio to South America

Cheapest flights from San Antonio to South AmericaExplore the most affordable flight options available from San Antonio to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on décembre 28, 2025.

Explore the most affordable flight options available from San Antonio to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on décembre 28, 2025.

Find flight deals from San Antonio to South America

Keep the following information in mind while searching for San Antonio to South America flight deals. Data was last updated décembre 28, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Antonio to South America that are best for you.

Best time to book a flight from San Antonio to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Antonio with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to South America

What is the cheapest month to book a flight from San Antonio to South America?

Reviews of airlines servicing South America

Read through reviews of airlines operating flights from San Antonio to South America, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from San Antonio to South America?

How long is the flight from San Antonio to South America?

What are the cheapest airlines to fly from San Antonio to South America one-way?

What are the most popular routes from San Antonio to South America?

Can I find deals for flights from San Antonio to South America that include hotel bookings?

How can I find direct flights from San Antonio to South America?

Can I find deals for business class flights from San Antonio to South America?

What is the cheapest month to book a flight from San Antonio to South America?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Antonio to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from San Antonio to South America

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from San Antonio to South America
Explore the most affordable flight options available from San Antonio to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on décembre 28, 2025.