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South America

$128+ Cheap flights from San Antonio (SAT) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — BOG
Aug 21 — Aug 281
Thu 8/21
Thu 8/28
1 adult, Economy
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Cheap flight deals from San Antonio to South America

Keep the following information in mind while searching for San Antonio to South America flight deals. Data was last updated August 16, 2025.

Round-trip from

$312
(Kiwi.com)

One-way from

$128
(Expedia)

Popular in

April

Cheapest in

November

Average price

$1,048
From San Antonio to South America
Search Deals
One-way flight from San Antonio to South America
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Highest demand for flights based on searches. 59% potential increase in price ($2,362 potential increase over avg. RT price).
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Cheapest flight prices on average. 54% potential price decrease ($574 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from San Antonio to South America

Cheapest flights from San Antonio to South America
Explore the most affordable flight options available from San Antonio to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/127:17 pmSAT - MDE
1 stop17h 57mSpirit Airlines
Thu 9/181:24 amMDE - SAT
1 stop16h 48mSpirit Airlines
Deal found 8/15$331
This Travelocity deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/37:17 pmSAT - BOG
1 stop17h 53mSpirit Airlines
Thu 10/92:10 pmBOG - SAT
2 stops25h 45mSpirit Airlines
Deal found 8/15$334
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/277:19 pmSAT - MDE
1 stop17h 52mSpirit Airlines
Thu 10/301:12 amMDE - SAT
1 stop17h 01mSpirit Airlines
Deal found 8/15$337
This Expedia deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/282:54 pmSAT - MDE
2 stops9h 34mSpirit Airlines
Sat 10/41:24 amMDE - SAT
1 stop16h 49mSpirit Airlines
Deal found 8/13$345
This FlightHub deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/72:54 pmSAT - MDE
2 stops9h 34mSpirit Airlines
Sat 9/201:24 amMDE - SAT
1 stop16h 48mSpirit Airlines
Deal found 8/15$348
This FlightHub deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/187:17 pmSAT - MDE
1 stop29h 11mSpirit Airlines
Wed 9/242:00 pmMDE - SAT
1 stop23h 49mSpirit Airlines
Deal found 8/15$362
This Cheapflightsfares deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:17 pmSAT - BOG
1 stop17h 53mSpirit Airlines
Thu 10/22:05 pmBOG - SAT
2 stops21h 35mSpirit Airlines
Deal found 8/15$365
This FlightHub deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/187:17 pmSAT - BOG
1 stop17h 53mSpirit Airlines
Sat 9/272:05 pmBOG - SAT
2 stops23h 44mSpirit Airlines
Deal found 8/15$367
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/277:19 pmSAT - MDE
1 stop17h 52mSpirit Airlines
Tue 11/43:22 pmMDE - SAT
1 stop24h 49mSpirit Airlines
Deal found 8/15$371
This KAYAK deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/257:17 pmSAT - MDE
1 stop29h 11mSpirit Airlines
Sun 9/281:24 amMDE - SAT
1 stop16h 48mSpirit Airlines
Deal found 8/15$375
This Cheapflightsfares deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2212:45 pmSAT - MDE
2 stops24h 29mSpirit Airlines
Sun 9/281:24 amMDE - SAT
1 stop16h 48mSpirit Airlines
Deal found 8/14$377
This FlightHub deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:17 pmSAT - MDE
1 stop29h 11mSpirit Airlines
Thu 10/22:09 pmMDE - SAT
2 stops21h 31mSpirit Airlines
Deal found 8/14$378

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
Use the filters below to find and compare flights from San Antonio to South America that are best for you.

Fly from

San Antonio

Fly to

South America

Route

Depart

Return

Price

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Fri 9/26

7:17 pm-1:14 pm

1 stop17h 57m

Medellín Jose Maria Cordova Intl

Wed 10/1

1:24 am-6:12 pm

1 stop16h 48m

$331

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Sun 9/28

7:17 pm-1:14 pm

1 stop17h 57m

Medellín Jose Maria Cordova Intl

Sat 10/4

1:24 am-6:13 pm

1 stop16h 49m

$331

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Fri 9/12

7:17 pm-1:14 pm

1 stop17h 57m

Medellín Jose Maria Cordova Intl

Thu 9/18

1:24 am-6:12 pm

1 stop16h 48m

$331

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

Fri 10/3

7:17 pm-1:10 pm

1 stop17h 53m

Bogotá El Dorado

Thu 10/9

2:10 pm-3:55 pm

2 stops25h 45m

$334

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Mon 10/27

7:19 pm-1:11 pm

1 stop17h 52m

Medellín Jose Maria Cordova Intl

Thu 10/30

1:12 am-6:13 pm

1 stop17h 01m

$337

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Sun 9/7

2:54 pm-12:28 am

2 stops9h 34m

Medellín Jose Maria Cordova Intl

Sat 9/20

1:24 am-6:12 pm

1 stop16h 48m

$348

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Thu 9/25

2:54 pm-12:28 am

2 stops9h 34m

Medellín Jose Maria Cordova Intl

Sun 9/28

1:24 am-6:12 pm

1 stop16h 48m

$348

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Sun 11/9

6:00 am-1:55 pm

1 stop6h 55m

Medellín Jose Maria Cordova Intl

Sat 11/15

2:54 pm-10:27 pm

1 stop8h 33m

$357

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

Fri 9/26

7:17 pm-1:10 pm

1 stop17h 53m

Bogotá El Dorado

Thu 10/2

2:05 pm-11:40 am

2 stops21h 35m

$365

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

Thu 9/18

7:17 pm-1:10 pm

1 stop17h 53m

Bogotá El Dorado

Sat 9/27

2:05 pm-1:49 pm

2 stops23h 44m

$367

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/15

Showing 1-10 of 60 results
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Best time to book a flight from San Antonio to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to South America

What is the cheapest month to book a flight from San Antonio to South America?

Currently, May is the cheapest month in which you can book a flight from San Antonio to South America (average of $359). Flying from San Antonio to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAT to SA?

Find hourly flight availability from San Antonio to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 16, 2025.

When flying from San Antonio to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated August 16, 2025.
Read through reviews of airlines operating flights from San Antonio to South America, such as Delta, LATAM Airlines, and Aeromexico. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,985 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,985 reviews
Delta
8.0
Very good
7,985 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,840 reviews
Delta
8.0
Very good
7,985 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Aeromexico
7.5
Good
1,722 reviews
Delta
8.0
Very good
7,985 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,916 reviews
Delta
8.0
Very good
7,985 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,985 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from San Antonio to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Antonio to South America?

    Located just 7.6 mi from the city center, San Antonio (SAT) is the airport most travelers will use when flying to South America from San Antonio.

  • What are the cheapest airlines to fly from San Antonio to South America one-way?

    The cheapest airlines for a one-way flight from San Antonio to South America are Spirit Airlines ($128), Viva ($157), and United Airlines ($233).

  • What are the most popular routes from San Antonio to South America?

    When deciding which route to take from San Antonio to South America consider San Antonio - Cartagena Rafael Nunez, San Antonio - Medellín Jose Maria Cordova Intl or San Antonio - Bogotá El Dorado as they are the most popular.

  • Can I find deals for flights from San Antonio to South America that include hotel bookings?

    Yes. In addition to deals on San Antonio to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to South America.

  • Can I find deals for business class flights from San Antonio to South America?

    Yes. Cheapflights offers flight deals from San Antonio to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to South America?

    Currently, May is the cheapest month in which you can book a flight from San Antonio to South America (average of $359). Flying from San Antonio to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Antonio to South America

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Top 7 airlines flying from San Antonio to South America

Discover the top 7 airlines that operate flights from San Antonio to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$233Average$474FlexibilityNo cancel feeOn-time65%
VivaCheapest$338Average$532FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$386Average$761FlexibilityNo cancel feeOn-time71%
DeltaCheapest$401Average$720FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$414Average$904FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$419Average$858FlexibilityNo cancel feeOn-time81%
AeromexicoCheapest$530Average$676FlexibilityNo cancel feeOn-timeN/A

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