HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South America

$129+ Cheap flights from San Antonio (SAT) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — BOG
Dec 24 — Dec 311
Wed 12/24
Wed 12/31
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Antonio to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Antonio to South America

Keep the following information in mind while searching for San Antonio to South America flight deals. Data was last updated November 24, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$300
(KAYAK)

One-way from

$129
(Trip.com)

Popular in

April

Cheapest in

September

Average price

$911
Provider with most accurate pricing for San Antonio-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Antonio-Sao Paulo (SAO) flights.
Search Deals
From San Antonio to South America
Search Deals
One-way flight from San Antonio to South America
Search Deals
Highest demand for flights based on searches. 47% potential increase in price ($1,197 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 26% potential price decrease ($282 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from San Antonio to South America

Cheapest flights from San Antonio to South America
Explore the most affordable flight options available from San Antonio to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 24, 2025.

This Priceline deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/81:55 pmSAT - MDE
1 stop10h 14mSpirit Airlines
Fri 12/123:10 pmMDE - SAT
1 stop9h 16mSpirit Airlines
Deal found 11/24$300
This Spirit Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:10 pmSAT - CTG
2 stops18h 00mSpirit Airlines
Fri 12/122:15 pmCTG - SAT
1 stop10h 11mSpirit Airlines
Deal found 11/23$356
This CheapOair deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/302:39 pmSAT - BOG
1 stop9h 33mSpirit Airlines
Wed 2/111:45 pmBOG - SAT
1 stop11h 07mSpirit Airlines
Deal found 11/22$360
This Priceline deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/27:37 pmSAT - MDE
1 stop17h 26mSpirit Airlines
Fri 12/123:10 pmMDE - SAT
1 stop9h 16mSpirit Airlines
Deal found 11/22$365
This KAYAK deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:55 pmSAT - MDE
1 stop10h 14mSpirit Airlines
Sun 12/282:25 amMDE - SAT
1 stop22h 01mSpirit Airlines
Deal found 11/22$376
This KAYAK deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/133:10 pmSAT - BOG
1 stop20h 42mSpirit Airlines
Sat 12/203:05 pmBOG - SAT
1 stop9h 21mSpirit Airlines
Deal found 11/22$388
This KAYAK deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/133:10 pmSAT - BOG
1 stop20h 42mSpirit Airlines
Thu 2/191:47 pmBOG - SAT
1 stop11h 06mSpirit Airlines
Deal found 11/22$412
This Kiwi.com deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/297:37 pmSAT - CTG
1 stop16h 48mSpirit Airlines
Fri 12/122:15 pmCTG - SAT
1 stop10h 11mSpirit Airlines
Deal found 11/22$412
This Delta deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/255:15 amSAT - BOG
1 stop13h 15mDelta
Fri 12/59:00 amBOG - SAT
1 stop15h 17mDelta
Deal found 11/22$415
This KAYAK deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/297:37 pmSAT - CTG
1 stop16h 48mSpirit Airlines
Thu 12/112:15 pmCTG - SAT
1 stop10h 11mSpirit Airlines
Deal found 11/22$416
This Kiwi.com deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/17:37 pmSAT - CTG
1 stop16h 48mSpirit Airlines
Thu 12/112:15 pmCTG - SAT
1 stop10h 11mSpirit Airlines
Deal found 11/22$417
This Delta deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:10 amSAT - CTG
1 stop8h 07mDelta
Tue 12/93:32 pmCTG - SAT
1 stop10h 02mDelta
Deal found 11/22$418

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
Use the filters below to find and compare flights from San Antonio to South America that are best for you.

Fly from

San Antonio

Fly to

South America

Route

Depart

Return

Price

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Mon 12/8

1:55 pm-1:09 am

1 stop10h 14m

Medellín Jose Maria Cordova Intl

Fri 12/12

3:10 pm-11:26 pm

1 stop9h 16m

$300

San AntonioCartagena

SAT - CTG

SATCTG

San Antonio

Tue 1/27

6:30 am-1:15 pm

2 stops29h 45m

Cartagena Rafael Nunez

Wed 2/4

2:21 pm-9:40 am

1 stop20h 19m

$348

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Mon 1/19

10:35 am-9:40 pm

1 stop10h 05m

Medellín Jose Maria Cordova Intl

Fri 1/23

1:00 pm-9:40 am

1 stop21h 40m

$353

San AntonioCartagena

SAT - CTG

SATCTG

San Antonio

Mon 12/8

6:10 pm-1:10 pm

2 stops18h 00m

Cartagena Rafael Nunez

Fri 12/12

2:15 pm-11:26 pm

1 stop10h 11m

$356

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

Tue 12/30

2:39 pm-1:12 am

1 stop9h 33m

Bogotá El Dorado

Wed 2/11

1:45 pm-11:52 pm

1 stop11h 07m

$360

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Thu 12/11

1:55 pm-1:09 am

1 stop10h 14m

Medellín Jose Maria Cordova Intl

Sun 12/28

2:25 am-11:26 pm

1 stop22h 01m

$376

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Tue 1/20

6:30 am-2:15 pm

2 stops30h 45m

Medellín Jose Maria Cordova Intl

Tue 1/27

2:50 pm-11:52 pm

1 stop10h 02m

$379

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Fri 2/27

10:26 am-2:13 pm

1 stop26h 47m

Medellín Jose Maria Cordova Intl

Tue 3/3

2:54 pm-11:53 pm

1 stop9h 59m

$389

San AntonioLima

SAT - LIM

SATLIM

San Antonio

Mon 1/26

10:35 am-10:35 pm

1 stop11h 00m

Lima J Chavez Intl

Thu 1/29

11:33 pm-9:40 am

1 stop11h 07m

$404

San AntonioLima

SAT - LIM

SATLIM

San Antonio

Fri 1/16

10:35 am-10:35 pm

1 stop11h 00m

Lima J Chavez Intl

Sat 1/31

11:33 pm-9:40 am

1 stop11h 07m

$410

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from San Antonio to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to South America

What is the cheapest month to book a flight from San Antonio to South America?

Currently, May is the cheapest month in which you can book a flight from San Antonio to South America (average of $161). Flying from San Antonio to South America in March is currently the most expensive (average of $286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAT to SA?

Find hourly flight availability from San Antonio to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 24, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 9% on flights from San Antonio to South America by exploring options for tickets in the evening.

What is the cheapest day to fly from San Antonio to South America?

Use this chart to determine the cheapest time to fly round-trip from San Antonio to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Antonio to South America flight should consider departing on Saturday evenings when fares are most often at their lowest. Wednesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated November 24, 2025.
Read through reviews of airlines operating flights from San Antonio to South America, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Boarding

8.1

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Boarding

8.1

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,887 reviews
Delta
7.9
Good
7,998 reviews

Boarding

8.1

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,044 reviews
Delta
7.9
Good
7,998 reviews

Boarding

8.1

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Aeromexico
7.4
Good
1,659 reviews
Delta
7.9
Good
7,998 reviews

Boarding

8.1

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,042 reviews
Delta
7.9
Good
7,998 reviews

Boarding

8.1

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Antonio to South America?

    Located just 7.6 mi from the city center, San Antonio (SAT) is the airport most travelers will use when flying to South America from San Antonio.

  • How long is the flight from San Antonio to South America?

    There are many flights that can get you from San Antonio to South America in 10h 14m. Fly via Spirit Airlines, United Airlines, or Delta to get the fastest option. The distance between San Antonio and South America is about 2203 mi. This flight may include one or multiple stops.

  • What are the most popular routes from San Antonio to South America?

    When deciding which route to take from San Antonio to South America consider San Antonio - Medellín Jose Maria Cordova Intl, San Antonio - Lima J Chavez Intl or San Antonio - Bogotá El Dorado as they are the most popular.

  • Can I find deals for flights from San Antonio to South America that include hotel bookings?

    Yes. In addition to deals on San Antonio to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to South America.

  • Can I find deals for business class flights from San Antonio to South America?

    Yes. Cheapflights offers flight deals from San Antonio to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to South America?

    Currently, May is the cheapest month in which you can book a flight from San Antonio to South America (average of $161). Flying from San Antonio to South America in March is currently the most expensive (average of $286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Antonio to South America

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to John F Kennedy Intl flights
Dallas/Fort Worth to LaGuardia flights
Dallas/Fort Worth to Newark flights
Hobby to LaGuardia flights
Dallas/Fort Worth to Las Vegas flights
Hobby to Newark flights
Dallas/Fort Worth to Seattle flights
Dallas/Fort Worth to Los Angeles flights
Dallas/Fort Worth to Cancún flights
Hobby to John F Kennedy Intl flights
Dallas/Fort Worth to San Francisco flights
Dallas/Fort Worth to Denver flights
Dallas/Fort Worth to O'Hare Intl flights
George Bush Intcntl to Cancún flights
Dallas/Fort Worth to Orlando flights
George Bush Intcntl to LaGuardia flights
George Bush Intcntl to Newark flights
Hobby to Denver flights
Dallas/Fort Worth to Fort Lauderdale flights
Dallas/Fort Worth to Mexico City flights
George Bush Intcntl to John F Kennedy Intl flights
Hobby to Las Vegas flights
Dallas/Fort Worth to Luis Munoz Marin Intl flights
Dallas/Fort Worth to Baltimore flights
Hobby to Seattle flights
Hobby to Cancún flights
George Bush Intcntl to Denver flights
Dallas/Fort Worth to Dulles Intl flights
Dallas/Fort Worth to Narita flights
Austin to Newark flights
George Bush Intcntl to Las Vegas flights
Austin to John F Kennedy Intl flights
Dallas/Fort Worth to Atlanta flights
Love Field to Las Vegas flights
Hobby to Los Angeles flights
Dallas/Fort Worth to Miami flights
Austin to Las Vegas flights
Dallas/Fort Worth to Boston flights
Dallas/Fort Worth to Haneda flights
Dallas/Fort Worth to Sky Harbor Intl flights
Hobby to Mexico City flights
Hobby to Orlando flights
George Bush Intcntl to Seattle flights
Love Field to LaGuardia flights
Dallas/Fort Worth to Cozumel flights
Dallas/Fort Worth to Heathrow flights
Hobby to Haneda flights
Dallas/Fort Worth to Santa Ana flights
Dallas/Fort Worth to Ontario flights
Austin to Denver flights

Top 5 airlines flying from San Antonio to South America

Discover the top 5 airlines that operate flights from San Antonio to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$386Average$735FlexibilityNo cancel feeOn-time71%
DeltaCheapest$412Average$702FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$414Average$877FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$419Average$851FlexibilityNo cancel feeOn-time81%
AeromexicoCheapest$648Average$725FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.