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South America

$143+ Cheap flights from San Antonio (SAT) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — BOG
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from San Antonio to South America

Cheapest flights from San Antonio to South America
Explore the most affordable flight options available from San Antonio to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This FlightHub deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3012:45 pmSAT - BOG
2 stops11h 27mSpirit Airlines
Wed 2/111:45 pmBOG - SAT
1 stop11h 07mSpirit Airlines
Deal found 12/3$326
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:00 amSAT - BOG
1 stop17h 30mAmerican Airlines
Thu 12/1111:55 pmBOG - SAT
1 stop18h 13mAmerican Airlines
Deal found 12/2$415
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/95:20 amSAT - CTG
1 stop7h 10mAmerican Airlines
Tue 2/104:30 pmCTG - SAT
1 stop8h 29mAmerican Airlines
Deal found 12/3$418
This American Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:23 amSAT - BOG
1 stop7h 52mAmerican Airlines
Fri 12/511:55 pmBOG - SAT
1 stop18h 13mAmerican Airlines
Deal found 12/1$440
This Expedia deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/133:10 pmSAT - MDE
2 stops8h 59mSpirit Airlines
Mon 12/223:10 pmMDE - SAT
1 stop9h 16mSpirit Airlines
Deal found 12/2$440
This Kiwi.com deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:10 amSAT - CTG
2 stops27h 00mMultiple Airlines
Fri 2/132:21 pmCTG - SAT
1 stop20h 09mMultiple Airlines
Deal found 12/3$453
This Expedia deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/242:39 pmSAT - GYE
1 stop8h 14mSpirit Airlines
Sat 12/2712:49 amGYE - SAT
2 stops12h 01mSpirit Airlines
Deal found 12/3$468
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:04 pmSAT - BOG
1 stop9h 06mUnited Airlines
Mon 4/612:14 amBOG - SAT
1 stop13h 00mUnited Airlines
Deal found 12/3$470
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:50 amSAT - MDE
1 stop25h 05mMultiple Airlines
Wed 12/243:10 pmMDE - SAT
1 stop9h 16mMultiple Airlines
Deal found 12/2$486
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:50 amSAT - MDE
1 stop25h 05mMultiple Airlines
Fri 12/192:25 amMDE - SAT
1 stop22h 01mMultiple Airlines
Deal found 12/2$493
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:50 amSAT - MDE
1 stop25h 05mMultiple Airlines
Tue 12/232:54 pmMDE - SAT
1 stop21h 56mMultiple Airlines
Deal found 12/2$494
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:10 amSAT - MDE
1 stop24h 45mMultiple Airlines
Wed 12/243:10 pmMDE - SAT
1 stop9h 16mMultiple Airlines
Deal found 12/2$497

Find flight deals from San Antonio to South America

Keep the following information in mind while searching for San Antonio to South America flight deals. Data was last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$248
(Mytrip)

One-way from

$143
(Trip.com)

Popular in

April

Cheapest in

September

Average price

$1,346
Provider with most accurate pricing for San Antonio-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Antonio-Sao Paulo (SAO) flights.
Search Deals
From San Antonio to South America
Search Deals
One-way flight from San Antonio to South America
Search Deals
Highest demand for flights based on searches. 47% potential increase in price ($1,197 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 26% potential price decrease ($282 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from San Antonio to South America that are best for you.

Fly from

San Antonio

Fly to

South America

Route

Depart

Return

Price

San AntonioGuayaquil

SAT - GYE

SATGYE

San Antonio

Sat 1/17

6:30 am-12:21 am

2 stops16h 51m

Guayaquil Jose Joaquin de Olmedo

Tue 1/20

1:26 am-11:52 pm

2 stops23h 26m

$248

San AntonioCartagena

SAT - CTG

SATCTG

San Antonio

Thu 1/22

10:35 am-1:15 pm

1 stop25h 40m

Cartagena Rafael Nunez

Fri 1/30

2:21 pm-9:40 am

1 stop20h 19m

$305

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

Tue 12/30

12:45 pm-1:12 am

2 stops11h 27m

Bogotá El Dorado

Wed 2/11

1:45 pm-11:52 pm

1 stop11h 07m

$326

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

Thu 1/22

6:30 am-2:07 pm

2 stops30h 37m

Bogotá El Dorado

Mon 1/26

1:45 pm-11:52 pm

1 stop11h 07m

$331

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

Mon 2/2

10:35 am-12:50 pm

2 stops25h 15m

Bogotá El Dorado

Fri 2/6

1:45 pm-11:52 pm

1 stop11h 07m

$337

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

Sun 1/18

10:35 am-2:07 pm

1 stop26h 32m

Bogotá El Dorado

Sat 1/24

3:06 pm-9:40 am

1 stop19h 34m

$349

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Fri 1/16

10:35 am-9:40 pm

1 stop10h 05m

Medellín Jose Maria Cordova Intl

Fri 1/23

1:00 pm-9:40 am

1 stop21h 40m

$352

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Mon 1/26

10:35 am-1:55 pm

2 stops26h 20m

Medellín Jose Maria Cordova Intl

Fri 1/30

3:15 pm-9:40 am

1 stop19h 25m

$353

San AntonioCartagena

SAT - CTG

SATCTG

San Antonio

Thu 1/22

10:35 am-1:15 pm

1 stop25h 40m

Cartagena Rafael Nunez

Tue 1/27

2:21 pm-11:52 pm

2 stops34h 31m

$361

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

Sat 1/17

10:35 am-2:07 pm

1 stop26h 32m

Bogotá El Dorado

Sat 1/24

3:06 pm-9:40 am

1 stop19h 34m

$379

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/2

Showing 1-10 of 60 results
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Best time to book a flight from San Antonio to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to South America

What is the cheapest month to book a flight from San Antonio to South America?

Currently, October is the cheapest month in which you can book a flight from San Antonio to South America (average of $103). Flying from San Antonio to South America in August is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAT to SA?

Find hourly flight availability from San Antonio to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 13% on flights from San Antonio to South America by exploring options for tickets in the morning.

What is the cheapest day to fly from San Antonio to South America?

Use this chart to determine the cheapest time to fly round-trip from San Antonio to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Antonio to South America flight should consider departing on Saturday evenings when fares are most often at their lowest. Wednesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated December 4, 2025.
Read through reviews of airlines operating flights from San Antonio to South America, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,890 reviews
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,066 reviews
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,046 reviews
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,159 reviews
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Antonio to South America?

    Located just 7.6 mi from the city center, San Antonio (SAT) is the airport most travelers will use when flying to South America from San Antonio.

  • How long is the flight from San Antonio to South America?

    There are many flights that can get you from San Antonio to South America in 16h 07m. Fly via Spirit Airlines, American Airlines, or United Airlines to get the fastest option. The distance between San Antonio and South America is about 4706 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from San Antonio to South America one-way?

    The cheapest airlines for a one-way flight from San Antonio to South America are Delta ($178), United Airlines ($178), and American Airlines ($184).

  • What are the most popular routes from San Antonio to South America?

    When deciding which route to take from San Antonio to South America consider San Antonio - Medellín Jose Maria Cordova Intl, San Antonio - Lima J Chavez Intl or San Antonio - Bogotá El Dorado as they are the most popular.

  • Can I find deals for flights from San Antonio to South America that include hotel bookings?

    Yes. In addition to deals on San Antonio to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to South America.

  • Can I find deals for business class flights from San Antonio to South America?

    Yes. Cheapflights offers flight deals from San Antonio to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to South America?

    Currently, October is the cheapest month in which you can book a flight from San Antonio to South America (average of $103). Flying from San Antonio to South America in August is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Antonio to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from San Antonio to South America

Discover the top 6 airlines that operate flights from San Antonio to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$325Average$571FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$401Average$731FlexibilityNo cancel feeOn-time71%
DeltaCheapest$412Average$712FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$414Average$860FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$539Average$886FlexibilityNo cancel feeOn-time81%
AeromexicoCheapest$648Average$725FlexibilityNo cancel feeOn-timeN/A

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