South America

$160+ Cheap flights from San Antonio (SAT) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/11. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — BOG
Apr 9 — Apr 161
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Cheap flight deals from San Antonio to South America

Cheapest flights from San Antonio to South America
Explore the most affordable flight options available from San Antonio to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/210:22 am
SAT
-
MDE
1 stop13h 59m
Spirit Airlines
Wed 4/81:17 am
MDE
-
SAT
1 stop8h 10m
Spirit Airlines
Deal found 3/5$361
This CheapOair deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/910:22 am
SAT
-
BOG
1 stop26h 49m
Spirit Airlines
Sun 4/122:10 pm
BOG
-
SAT
1 stop19h 17m
Spirit Airlines
Deal found 3/8$362
This Cheapflightsfares deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:00 am
SAT
-
BOG
1 stop7h 12m
Spirit Airlines
Sat 5/162:07 pm
BOG
-
SAT
1 stop9h 44m
Spirit Airlines
Deal found 3/7$368
This Expedia deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/310:22 am
SAT
-
MDE
1 stop13h 59m
Spirit Airlines
Fri 4/102:17 pm
MDE
-
SAT
2 stops22h 10m
Spirit Airlines
Deal found 3/6$368
This Cheapflightsfares deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/210:22 am
SAT
-
MDE
1 stop13h 59m
Spirit Airlines
Sun 4/51:17 am
MDE
-
SAT
1 stop8h 10m
Spirit Airlines
Deal found 3/6$371
This Priceline deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/210:22 am
SAT
-
MDE
1 stop13h 59m
Spirit Airlines
Tue 4/72:17 pm
MDE
-
SAT
2 stops22h 10m
Spirit Airlines
Deal found 3/5$373
This Orbitz deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:00 am
SAT
-
CTG
1 stop6h 06m
Spirit Airlines
Thu 4/301:11 pm
CTG
-
SAT
1 stop10h 40m
Spirit Airlines
Deal found 3/9$374
This CheapOair deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/301:22 pm
SAT
-
BOG
1 stop22h 33m
Spirit Airlines
Sat 4/112:10 pm
BOG
-
SAT
1 stop19h 17m
Spirit Airlines
Deal found 3/5$378
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3110:22 am
SAT
-
CTG
1 stop25h 44m
Spirit Airlines
Tue 4/71:14 pm
CTG
-
SAT
1 stop20h 13m
Spirit Airlines
Deal found 3/6$378
This CheapOair deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/310:22 am
SAT
-
MDE
1 stop13h 59m
Spirit Airlines
Tue 4/72:17 pm
MDE
-
SAT
2 stops22h 10m
Spirit Airlines
Deal found 3/7$378
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:13 pm
SAT
-
CTG
2 stops21h 53m
Multiple Airlines
Tue 4/71:14 pm
CTG
-
SAT
1 stop20h 13m
Multiple Airlines
Deal found 3/6$390
This CheapOair deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:22 am
SAT
-
BOG
1 stop26h 49m
Spirit Airlines
Sun 4/512:50 pm
BOG
-
SAT
2 stops20h 37m
Spirit Airlines
Deal found 3/9$391

Find flight deals from San Antonio to South America

Keep the following information in mind while searching for San Antonio to South America flight deals. Data was last updated March 10, 2026.

Round-trip from

$361
(Cheapflightsfares)

One-way from

$160
(Cheapflightsfares)

Popular in

July

Cheapest in

January

Average price

$545
From San Antonio to South America
One-way flight from San Antonio to South America
Highest demand for flights based on searches. 11% potential increase in price ($76 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from San Antonio to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Thu 4/2

10:22 am-12:21 am

1 stop13h 59m

Medellín Jose Maria Cordova Intl

Mon 4/6

1:17 am-9:27 am

1 stop8h 10m

$361

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Thu 4/2

10:22 am-12:21 am

1 stop13h 59m

Medellín Jose Maria Cordova Intl

Sun 4/5

1:17 am-9:27 am

1 stop8h 10m

$371

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Fri 4/3

10:22 am-12:21 am

1 stop13h 59m

Medellín Jose Maria Cordova Intl

Tue 4/7

2:17 pm-12:27 pm

2 stops22h 10m

$378

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Thu 4/2

10:22 am-12:21 am

1 stop13h 59m

Medellín Jose Maria Cordova Intl

Thu 4/9

2:17 pm-12:27 pm

2 stops22h 10m

$407

San AntonioCali

SAT - CLO

SATCLO

San Antonio

Thu 4/2

10:22 am-1:19 pm

1 stop26h 57m

Cali Alfonso B. Aragon Intl

Mon 4/6

2:24 pm-9:27 am

1 stop19h 03m

$409

San AntonioCartagena

SAT - CTG

SATCTG

San Antonio

Fri 4/3

10:22 am-2:41 am

2 stops16h 19m

Cartagena Rafael Nunez

Thu 4/9

1:14 pm-9:27 am

1 stop20h 13m

$437

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

Wed 4/1

1:22 pm-1:11 pm

2 stops23h 49m

Bogotá El Dorado

Sun 4/5

12:50 pm-9:27 am

2 stops44h 37m

$443

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Mon 4/13

10:22 am-12:52 pm

2 stops26h 30m

Medellín Jose Maria Cordova Intl

Thu 4/23

2:06 pm-11:51 pm

1 stop9h 45m

$443

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Wed 4/15

2:12 pm-1:08 pm

2 stops22h 56m

Medellín Jose Maria Cordova Intl

Sun 4/19

2:06 pm-11:51 pm

1 stop9h 45m

$453

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Thu 4/2

10:22 am-12:21 am

1 stop13h 59m

Medellín Jose Maria Cordova Intl

Tue 4/7

4:48 am-12:27 pm

3 stops31h 39m

$458

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/7

Showing 1-10 of 60 resultsSorted by cheapest first
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6

Best time to book a flight from San Antonio to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to South America

What is the cheapest month to book a flight from San Antonio to South America?

Currently, October is the cheapest month in which you can book a flight from San Antonio to South America (average of $103). Flying from San Antonio to South America in August is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated March 10, 2026.
Read through reviews of airlines operating flights from San Antonio to South America, such as Delta,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.9

Crew

8.5

Comfort

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Overall

7.9

Crew

8.5

Comfort

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Overall

7.9

Crew

8.5

Comfort

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Overall

7.9

Crew

8.5

Comfort

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Overall

7.9

Crew

8.5

Comfort

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Overall

7.9

Crew

8.5

Comfort

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Antonio to South America?

    Located just 7.6 mi from the city center, San Antonio (SAT) is the airport most travelers will use when flying to South America from San Antonio.

  • How long is the flight from San Antonio to South America?

    There are many flights that can get you from San Antonio to South America in 12h 19m. Fly via Spirit Airlines, United Airlines, or Delta to get the fastest option. The distance between San Antonio and South America is about 2336 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from San Antonio to South America one-way?

    The cheapest airlines for a one-way flight from San Antonio to South America are Spirit Airlines ($117), Delta ($162), and American Airlines ($184).

  • What are the most popular routes from San Antonio to South America?

  • Can I find deals for flights from San Antonio to South America that include hotel bookings?

    Yes. In addition to deals on San Antonio to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to South America.

  • Can I find deals for business class flights from San Antonio to South America?

    Yes. Cheapflights offers flight deals from San Antonio to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to South America?

    Currently, October is the cheapest month in which you can book a flight from San Antonio to South America (average of $103). Flying from San Antonio to South America in August is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for San Antonio to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from San Antonio to South America

Discover the top 6 airlines that operate flights from San Antonio to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$285Average$504FlexibilityNo cancel feeOn-time65%
DeltaCheapest$414Average$803FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$414Average$769FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$414Average$840FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$548Average$851FlexibilityNo cancel feeOn-time81%
AeromexicoCheapest$648Average$732FlexibilityNo cancel feeOn-timeN/A

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