South America

$139+ Cheap flights from San Antonio (SAT) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — BOG
Nov 29 — Dec 61
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Antonio to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Antonio to South America

Keep the following information in mind while searching for San Antonio to South America flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$288
(CheapOair)

One-way from

$139
(CheapOair)

Popular in

April

Cheapest in

September
Provider with most accurate pricing for San Antonio-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for San Antonio-Sao Paulo (SAO) flights.
From San Antonio to South America
One-way flight from San Antonio to South America
Highest demand for flights based on searches. 47% potential increase in price ($1,196 potential increase over avg. RT price).
Cheapest flight prices on average. 26% potential price decrease ($282 potential savings vs. average RT price).

Find flight deals from San Antonio to South America

Cheapest flights from San Antonio to South America
Explore the most affordable flight options available from San Antonio to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This CheapOair deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/117:37 pmSAT - MDE
1 stop17h 26mSpirit Airlines
Sat 11/151:52 amMDE - SAT
1 stop17h 40mSpirit Airlines
Deal found 10/30$332
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/81:55 pmSAT - MDE
1 stop10h 14mSpirit Airlines
Sun 12/143:10 pmMDE - SAT
1 stop9h 16mSpirit Airlines
Deal found 10/28$344
This KAYAK deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/41:55 pmSAT - MDE
1 stop10h 14mSpirit Airlines
Sun 12/72:05 amMDE - SAT
1 stop22h 21mSpirit Airlines
Deal found 10/29$348
This CheapOair deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:37 pmSAT - MDE
1 stop17h 26mSpirit Airlines
Wed 12/173:10 pmMDE - SAT
2 stops21h 40mSpirit Airlines
Deal found 10/30$352
This CheapOair deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/302:39 pmSAT - BOG
1 stop9h 33mSpirit Airlines
Wed 2/111:57 pmBOG - SAT
1 stop9h 30mSpirit Airlines
Deal found 10/30$353
This KAYAK deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:37 pmSAT - BOG
1 stop17h 33mSpirit Airlines
Sun 11/163:15 pmBOG - SAT
1 stop28h 17mSpirit Airlines
Deal found 10/29$365
This CheapOair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/268:33 pmSAT - MDE
1 stop16h 28mSpirit Airlines
Sun 11/301:51 amMDE - SAT
1 stop17h 41mSpirit Airlines
Deal found 10/29$368
This KAYAK deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/27:37 pmSAT - MDE
2 stops38h 18mSpirit Airlines
Sun 12/72:05 amMDE - SAT
1 stop22h 21mSpirit Airlines
Deal found 10/30$369
This Orbitz deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:37 pmSAT - BOG
1 stop17h 33mSpirit Airlines
Wed 12/243:05 pmBOG - SAT
1 stop9h 21mSpirit Airlines
Deal found 10/30$374
This KAYAK deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/107:37 pmSAT - BOG
1 stop17h 33mSpirit Airlines
Thu 12/41:47 pmBOG - SAT
1 stop25h 28mSpirit Airlines
Deal found 10/28$381
This KAYAK deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/133:10 pmSAT - BOG
1 stop20h 42mSpirit Airlines
Fri 2/201:57 pmBOG - SAT
1 stop9h 30mSpirit Airlines
Deal found 10/30$382
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/67:37 pmSAT - BOG
1 stop17h 33mSpirit Airlines
Fri 12/53:05 pmBOG - SAT
1 stop9h 21mSpirit Airlines
Deal found 10/30$386

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from San Antonio to South America that are best for you.

Fly from

San Antonio

Fly to

South America

Route

Depart

Return

Price

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Sun 1/25

4:16 pm-12:56 am

1 stop7h 40m

Medellín Jose Maria Cordova Intl

Sat 1/31

1:51 am-3:11 pm

1 stop14h 20m

$297

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Thu 1/22

4:16 pm-12:56 am

1 stop7h 40m

Medellín Jose Maria Cordova Intl

Fri 1/30

12:09 pm-10:27 pm

1 stop11h 18m

$343

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Fri 1/9

4:16 pm-12:56 am

1 stop7h 40m

Medellín Jose Maria Cordova Intl

Tue 1/13

12:09 pm-10:27 pm

1 stop11h 18m

$347

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Mon 12/8

3:10 pm-1:09 am

2 stops8h 59m

Medellín Jose Maria Cordova Intl

Sun 12/14

3:10 pm-11:26 pm

1 stop9h 16m

$348

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Fri 1/23

4:16 pm-12:56 am

1 stop7h 40m

Medellín Jose Maria Cordova Intl

Sun 1/25

1:51 am-3:11 pm

1 stop14h 20m

$356

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Tue 1/20

6:00 am-11:03 am

1 stop28h 03m

Medellín Jose Maria Cordova Intl

Tue 1/27

12:09 pm-10:27 pm

1 stop11h 18m

$367

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

Sat 11/29

9:45 am-10:35 pm

1 stop11h 50m

Bogotá El Dorado

Sun 12/7

1:30 am-10:51 am

1 stop10h 21m

$415

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

Tue 3/10

5:30 am-2:33 pm

1 stop9h 03m

Bogotá El Dorado

Wed 3/11

3:55 pm-10:00 am

1 stop18h 05m

$415

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

Mon 11/10

5:15 am-2:25 pm

1 stop8h 10m

Bogotá El Dorado

Thu 12/4

6:35 pm-1:43 pm

2 stops20h 08m

$415

San AntonioBogotá

SAT - BOG

SATBOG

San Antonio

Tue 12/30

5:15 am-10:35 pm

1 stop16h 20m

Bogotá El Dorado

Tue 2/10

1:30 am-5:33 pm

1 stop17h 03m

$415

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from San Antonio to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to South America

What is the cheapest month to book a flight from San Antonio to South America?

Currently, October is the cheapest month in which you can book a flight from San Antonio to South America (average of $103). Flying from San Antonio to South America in December is currently the most expensive (average of $307). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAT to SA?

Find hourly flight availability from San Antonio to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 13% on flights from San Antonio to South America by exploring options for tickets in the morning.

What is the cheapest day to fly from San Antonio to South America?

Use this chart to determine the cheapest time to fly round-trip from San Antonio to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Antonio to South America flight should consider departing on Saturday evenings when fares are most often at their lowest. Wednesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated October 30, 2025.
Read through reviews of airlines operating flights from San Antonio to South America, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Overall

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Overall

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Overall

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Overall

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Overall

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Antonio to South America?

    Located just 7.6 mi from the city center, San Antonio (SAT) is the airport most travelers will use when flying to South America from San Antonio.

  • How long is the flight from San Antonio to South America?

    There are many flights that can get you from San Antonio to South America in 7h 40m. Fly via Spirit Airlines, United Airlines, or Delta to get the fastest option. The distance between San Antonio and South America is about 2203 mi. This flight may include one or multiple stops.

  • What are the most popular routes from San Antonio to South America?

  • Can I find deals for flights from San Antonio to South America that include hotel bookings?

    Yes. In addition to deals on San Antonio to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to South America.

  • Can I find deals for business class flights from San Antonio to South America?

    Yes. Cheapflights offers flight deals from San Antonio to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to South America?

    Currently, October is the cheapest month in which you can book a flight from San Antonio to South America (average of $103). Flying from San Antonio to South America in December is currently the most expensive (average of $307). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Antonio to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from San Antonio to South America

Discover the top 7 airlines that operate flights from San Antonio to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$233Average$433FlexibilityNo cancel feeOn-time65%
VivaCheapest$338Average$442FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$386Average$727FlexibilityNo cancel feeOn-time71%
DeltaCheapest$412Average$701FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$414Average$884FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$419Average$810FlexibilityNo cancel feeOn-time81%
AeromexicoCheapest$648Average$725FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.