South America

$694+ Cheap flights from Roanoke (ROA) to South America

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/21. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — BOG
Jul 16 — Jul 231
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Cheap flight deals from Roanoke to South America

Cheapest flights from Roanoke to South America
Explore the most affordable flight options available from Roanoke to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2026.

This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:20 am
ROA
-
UIO
2 stops17h 37m
American Airlines
Mon 8/3111:56 pm
UIO
-
ROA
2 stops16h 26m
American Airlines
Deal found 6/15$694
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:35 am
ROA
-
SCL
2 stops19h 50m
American Airlines
Mon 8/248:50 pm
SCL
-
ROA
2 stops17h 40m
American Airlines
Deal found 6/11$952
This KAYAK deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am
ROA
-
UIO
1 stop13h 59m
LATAM Airlines
Sun 8/3012:59 am
UIO
-
ROA
1 stop8h 38m
LATAM Airlines
Deal found 6/12$960
This LATAM Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:33 pm
ROA
-
GYE
2 stops16h 41m
LATAM Airlines
Thu 9/244:19 pm
GYE
-
ROA
2 stops29h 25m
LATAM Airlines
Deal found 6/14$1,019
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:32 pm
ROA
-
SCL
1 stop15h 43m
Delta
Mon 8/2411:00 pm
SCL
-
ROA
2 stops20h 19m
Delta
Deal found 6/11$1,032
This KAYAK deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:32 pm
ROA
-
SCL
3 stops21h 53m
LATAM Airlines
Mon 8/2411:00 pm
SCL
-
ROA
2 stops20h 19m
LATAM Airlines
Deal found 6/11$1,042
This Travelocity deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:40 pm
ROA
-
SCL
3 stops40h 09m
LATAM Airlines
Wed 9/309:40 pm
SCL
-
ROA
1 stop13h 53m
LATAM Airlines
Deal found 6/11$1,053
This Travelocity deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:40 pm
ROA
-
SCL
3 stops40h 09m
LATAM Airlines
Wed 9/3012:05 am
SCL
-
ROA
2 stops23h 39m
LATAM Airlines
Deal found 6/11$1,058
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am
ROA
-
UIO
1 stop13h 59m
Delta
Sun 8/3012:59 am
UIO
-
ROA
1 stop8h 38m
Delta
Deal found 6/15$1,101
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:40 am
ROA
-
GYE
2 stops17h 57m
United Airlines
Thu 9/2412:22 pm
GYE
-
ROA
2 stops20h 40m
United Airlines
Deal found 6/15$1,109
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:40 pm
ROA
-
SCL
1 stop12h 35m
Delta
Wed 9/3011:00 pm
SCL
-
ROA
2 stops24h 44m
Delta
Deal found 6/11$1,226
This oojo deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:05 pm
ROA
-
UIO
2 stops28h 35m
Avianca
Mon 8/3111:35 am
UIO
-
ROA
3 stops30h 31m
Avianca
Deal found 6/15$1,314

Find flight deals from Roanoke to South America

Keep the following information in mind while searching for Roanoke to South America flight deals. Data was last updated June 16, 2026.

Round-trip from

$694
(American Airlines)
From Roanoke to South America

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2026.
Use the filters below to find and compare flights from Roanoke to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Fri 8/21

7:20 am-11:57 pm

2 stops17h 37m

Quito Mariscal Sucr

Mon 8/31

11:56 pm-5:22 pm

2 stops16h 26m

$694

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

Mon 9/21

3:33 pm-7:14 am

2 stops16h 41m

Guayaquil Jose Joaquin de Olmedo

Thu 9/24

4:19 pm-10:44 pm

2 stops29h 25m

$1,019

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Tue 8/18

3:32 pm-7:15 am

1 stop15h 43m

Santiago Arturo Merino Benitez

Mon 8/24

11:00 pm-7:19 pm

2 stops20h 19m

$1,032

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Tue 8/18

3:32 pm-7:15 am

1 stop15h 43m

Santiago Arturo Merino Benitez

Mon 8/24

8:40 pm-2:51 pm

1 stop18h 11m

$1,048

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Fri 8/21

7:59 pm-11:00 pm

2 stops28h 01m

Quito Mariscal Sucr

Sun 8/30

12:59 am-10:37 am

1 stop8h 38m

$1,051

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Mon 9/21

6:40 pm-11:49 am

3 stops40h 09m

Santiago Arturo Merino Benitez

Wed 9/30

9:40 pm-10:33 am

1 stop13h 53m

$1,053

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Mon 9/21

6:40 pm-11:49 am

3 stops40h 09m

Santiago Arturo Merino Benitez

Wed 9/30

12:05 am-10:44 pm

2 stops23h 39m

$1,058
Quickest round-trip

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Fri 8/21

6:00 am-6:59 pm

1 stop13h 59m

Quito Mariscal Sucr

Sun 8/30

12:59 am-10:37 am

1 stop8h 38m

$1,101

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

Mon 9/21

6:40 am-11:37 pm

2 stops17h 57m

Guayaquil Jose Joaquin de Olmedo

Thu 9/24

12:22 pm-10:02 am

2 stops20h 40m

$1,109

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Mon 9/21

6:40 pm-8:15 am

1 stop12h 35m

Santiago Arturo Merino Benitez

Wed 9/30

11:00 pm-10:44 pm

2 stops24h 44m

$1,226

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Best time to book a flight from Roanoke to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to South America
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated June 16, 2026.
Read reviews from past customers who have flown LATAM Airlines from Roanoke to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.0

Overall

7.4

Comfort

7.3

Crew

8.0

Food

6.7

Boarding

7.5

Reviews

1 / 20
6.0
Good

Juan,Apr 2026

BOG - CLO

Very old aircraft and it was very dirty in the seats and floor

Entertainment

7.0

Overall

7.4

Comfort

7.3

Crew

8.0

Food

6.7

Boarding

7.5

Reviews

1 / 20
6.0
Good

Juan,Apr 2026

BOG - CLO

Very old aircraft and it was very dirty in the seats and floor

Related info for your journey

Find useful and relevant information for your journey from Roanoke to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Roanoke to South America?

    Most people fly from Roanoke (ROA) if they book a flight from Roanoke to South America. Roanoke is conveniently located just 4.2 mi from Roanoke’s city center.

  • How long is the flight from Roanoke to South America?

    American Airlines, LATAM Airlines, and Delta can get you from Roanoke to South America in just under 15h 43m. Your travel time can differ by up to 1h 54m. There are 4918 mi between Roanoke and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Roanoke to South America?

  • Can I find deals for flights from Roanoke to South America that include hotel bookings?

    Yes. In addition to deals on Roanoke to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to South America.

  • Can I find deals for business class flights from Roanoke to South America?

    Yes. Cheapflights offers flight deals from Roanoke to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Roanoke to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Roanoke to South America

Discover the top airline that operate flights from Roanoke to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$662Average$973FlexibilityNo cancel feeOn-time81%

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