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South America

$659+ Cheap flights from Roanoke (ROA) to South America

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — BOG
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Roanoke to South America

Keep the following information in mind while searching for Roanoke to South America flight deals. Data was last updated September 15, 2025.

Round-trip from

$659
(Delta)
From Roanoke to South America
Search Deals

Find flight deals from Roanoke to South America

Cheapest flights from Roanoke to South America
Explore the most affordable flight options available from Roanoke to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:00 amROA - UIO
1 stop12h 55mDelta
Mon 11/1012:55 amUIO - ROA
1 stop18h 20mDelta
Deal found 9/14$659
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:45 amROA - UIO
2 stops17h 45mUnited Airlines
Mon 11/101:35 amUIO - ROA
2 stops12h 37mUnited Airlines
Deal found 9/14$683
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/65:00 amROA - GYE
2 stops15h 10mAmerican Airlines
Wed 10/88:15 amGYE - ROA
2 stops23h 33mAmerican Airlines
Deal found 9/12$848
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/67:30 pmROA - GYE
2 stops16h 45mUnited Airlines
Wed 10/812:15 pmGYE - ROA
2 stops24h 49mUnited Airlines
Deal found 9/13$906
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:50 pmROA - GYE
2 stops16h 26mUnited Airlines
Thu 11/68:30 amGYE - ROA
2 stops53h 42mUnited Airlines
Deal found 9/15$935
This LATAM Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/811:20 amROA - SCL
2 stops17h 20mLATAM Airlines
Fri 12/126:40 amSCL - ROA
2 stops19h 40mLATAM Airlines
Deal found 9/13$1,114
This United deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2010:26 amROA - GYE
2 stops22h 49mMultiple Airlines
Sun 11/302:35 pmGYE - ROA
2 stops28h 08mMultiple Airlines
Deal found 9/14$1,268
This Avianca deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/67:30 pmROA - GYE
3 stops26h 20mAvianca
Wed 10/82:50 pmGYE - ROA
2 stops26h 55mAvianca
Deal found 9/12$1,390

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Roanoke to South America that are best for you.

Fly from

Roanoke

Fly to

South America

Route

Depart

Return

Price

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Sat 11/8

6:00 am-6:55 pm

1 stop12h 55m

Quito Mariscal Sucr

Mon 11/10

12:55 am-7:15 pm

1 stop18h 20m

$659

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Sat 11/8

6:45 am-12:30 am

2 stops17h 45m

Quito Mariscal Sucr

Mon 11/10

1:35 am-2:12 pm

2 stops12h 37m

$683

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

Mon 10/6

5:00 am-7:10 pm

2 stops15h 10m

Guayaquil Jose Joaquin de Olmedo

Wed 10/8

8:15 am-8:48 am

2 stops23h 33m

$848

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

Mon 10/6

7:30 pm-11:15 am

2 stops16h 45m

Guayaquil Jose Joaquin de Olmedo

Wed 10/8

12:15 pm-2:04 pm

2 stops24h 49m

$906

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

Thu 10/30

7:50 pm-11:16 am

2 stops16h 26m

Guayaquil Jose Joaquin de Olmedo

Thu 11/6

8:30 am-2:12 pm

2 stops53h 42m

$935

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Mon 12/8

3:50 pm-7:40 am

1 stop13h 50m

Santiago Arturo Merino Benitez

Thu 12/11

4:35 am-12:20 am

2 stops21h 45m

$1,114

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

Thu 11/20

10:26 am-9:15 am

2 stops22h 49m

Guayaquil Jose Joaquin de Olmedo

Sun 11/30

2:35 pm-6:43 pm

2 stops28h 08m

$1,268

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

Mon 10/6

7:30 pm-8:50 pm

3 stops26h 20m

Guayaquil Jose Joaquin de Olmedo

Wed 10/8

2:50 pm-6:45 pm

2 stops26h 55m

$1,390

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from Roanoke to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to South America

What is the cheapest month to book a flight from Roanoke to South America?

Currently, May is the cheapest month in which you can book a flight from Roanoke to South America (average of $359). Flying from Roanoke to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to SA?

Find hourly flight availability from Roanoke to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Roanoke to South America as you normally would.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 15, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Roanoke to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Roanoke to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to South America?

    Most people fly from Roanoke (ROA) if they book a flight from Roanoke to South America. Roanoke is conveniently located just 4.2 mi from Roanoke’s city center.

  • How long is the flight from Roanoke to South America?

    Delta, United Airlines, and American Airlines can get you from Roanoke to South America in just under 12h 55m. Your travel time can differ by up to 4h 50m. There are 2587 mi between Roanoke and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Roanoke to South America?

    The most popular route from Roanoke to South America is Roanoke - Rio de Janeiro–Galeão Intl. You may also consider Roanoke - Guayaquil Jose Joaquin de Olmedo or Roanoke - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from Roanoke to South America that include hotel bookings?

    Yes. In addition to deals on Roanoke to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to South America.

  • Can I find deals for business class flights from Roanoke to South America?

    Yes. Cheapflights offers flight deals from Roanoke to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to South America?

    Currently, May is the cheapest month in which you can book a flight from Roanoke to South America (average of $359). Flying from Roanoke to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Roanoke to South America

Discover the top 2 airlines that operate flights from Roanoke to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$410Average$484FlexibilityNo cancel feeOn-time71%
DeltaCheapest$501Average$741FlexibilityNo cancel feeOn-timeN/A

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