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South America

$652+ Cheap flights from Roanoke (ROA) to South America

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — BOG
Apr 18 — Apr 251
Sat 4/18
Sat 4/25
1 adult, Economy
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Cheap flight deals from Roanoke to South America

Cheapest flights from Roanoke to South America
Explore the most affordable flight options available from Roanoke to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 19, 2026.

This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:00 am
ROA
-
UIO
2 stops23h 43m
Delta
Tue 10/136:50 pm
UIO
-
ROA
2 stops14h 44m
Delta
Deal found 3/18$652
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:00 am
ROA
-
UIO
2 stops23h 43m
Delta
Wed 10/1412:59 am
UIO
-
ROA
1 stop21h 50m
Delta
Deal found 3/18$657
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/279:00 am
ROA
-
UIO
2 stops20h 43m
Delta
Wed 10/1412:59 am
UIO
-
ROA
1 stop21h 50m
Delta
Deal found 3/18$660
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:25 pm
ROA
-
UIO
2 stops14h 18m
Delta
Fri 10/166:15 pm
UIO
-
ROA
2 stops28h 34m
Delta
Deal found 3/18$662
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:00 am
ROA
-
UIO
2 stops20h 43m
Delta
Sun 10/1812:59 am
UIO
-
ROA
1 stop21h 50m
Delta
Deal found 3/18$667
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/279:00 am
ROA
-
UIO
2 stops20h 43m
Delta
Sat 10/1712:59 am
UIO
-
ROA
1 stop21h 50m
Delta
Deal found 3/18$670
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:00 am
ROA
-
UIO
2 stops20h 43m
Delta
Sun 10/186:50 pm
UIO
-
ROA
2 stops27h 00m
Delta
Deal found 3/18$672
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:59 pm
ROA
-
UIO
2 stops28h 26m
United Airlines
Mon 5/257:25 am
UIO
-
ROA
2 stops25h 21m
United Airlines
Deal found 3/18$687
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:20 am
ROA
-
UIO
2 stops18h 23m
Delta
Sat 10/176:50 pm
UIO
-
ROA
2 stops27h 59m
Delta
Deal found 3/18$689
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:00 pm
ROA
-
UIO
2 stops28h 25m
United Airlines
Mon 10/512:35 am
UIO
-
ROA
2 stops21h 48m
United Airlines
Deal found 3/16$707
This KAYAK deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am
ROA
-
UIO
1 stop13h 59m
LATAM Airlines
Tue 10/1312:59 am
UIO
-
ROA
1 stop12h 41m
LATAM Airlines
Deal found 3/18$712
This BusinessClass deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am
ROA
-
UIO
1 stop13h 59m
LATAM Airlines
Thu 10/1512:59 am
UIO
-
ROA
1 stop21h 50m
LATAM Airlines
Deal found 3/18$722

Find flight deals from Roanoke to South America

Keep the following information in mind while searching for Roanoke to South America flight deals. Data was last updated March 19, 2026.

Round-trip from

$687
(United Airlines)
From Roanoke to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 19, 2026.
Use the filters below to find and compare flights from Roanoke to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Sat 5/16

7:59 pm-11:25 pm

2 stops28h 26m

Quito Mariscal Sucr

Mon 5/25

7:25 am-9:46 am

2 stops25h 21m

$687

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Sat 4/11

2:04 pm-5:00 am

2 stops15h 56m

Quito Mariscal Sucr

Tue 4/14

12:35 am-12:37 am

2 stops23h 02m

$786
Quickest round-trip

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Sat 4/11

11:08 am-11:00 pm

2 stops12h 52m

Quito Mariscal Sucr

Tue 4/14

12:59 am-2:47 pm

1 stop12h 48m

$852

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Sat 5/16

6:00 am-11:45 am

2 stops30h 45m

Quito Mariscal Sucr

Sun 5/24

12:59 am-12:34 am

1 stop22h 35m

$882

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Sat 5/16

7:05 am-4:43 am

2 stops22h 38m

Quito Mariscal Sucr

Sun 5/24

12:59 am-12:34 am

1 stop22h 35m

$917

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Sat 9/5

8:00 pm-12:25 am

2 stops27h 25m

Rio de Janeiro–Galeão Intl

Sat 9/12

5:10 am-9:44 am

2 stops29h 34m

$1,089

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Mon 8/24

8:00 pm-12:25 am

2 stops27h 25m

Rio de Janeiro–Galeão Intl

Sun 8/30

5:10 am-9:44 am

2 stops29h 34m

$1,089

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Thu 9/3

11:20 am-6:00 am

2 stops18h 40m

Santiago Arturo Merino Benitez

Mon 9/7

8:40 pm-10:35 am

1 stop14h 55m

$1,235

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Sun 5/3

7:59 pm-8:15 am

2 stops35h 16m

Rio de Janeiro–Galeão Intl

Sun 5/10

9:05 pm-11:43 pm

2 stops51h 38m

$1,251

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Mon 8/24

7:50 pm-10:15 am

1 stop13h 25m

Rio de Janeiro–Galeão Intl

Sun 8/30

5:20 pm-11:50 pm

2 stops31h 30m

$1,292

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/18

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Best time to book a flight from Roanoke to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to South America

What is the cheapest month to book a flight from Roanoke to South America?

Currently, July is the cheapest month in which you can book a flight from Roanoke to South America (average of $377). Flying from Roanoke to South America in December is currently the most expensive (average of $628). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated March 19, 2026.
Read reviews from past customers who have flown LATAM Airlines from Roanoke to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.4
Good
1,915 reviews

Entertainment

7.0

Comfort

7.3

Food

6.7

Crew

8.0

Overall

7.4

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken
LATAM Airlines
7.4
Good
1,915 reviews
LATAM Airlines
7.4
Good
1,915 reviews

Entertainment

7.0

Comfort

7.3

Food

6.7

Crew

8.0

Overall

7.4

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken

Related info for your journey

Find useful and relevant information for your journey from Roanoke to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to South America?

    Most people fly from Roanoke (ROA) if they book a flight from Roanoke to South America. Roanoke is conveniently located just 4.2 mi from Roanoke’s city center.

  • How long is the flight from Roanoke to South America?

    United Airlines, LATAM Airlines, and Copa Airlines can get you from Roanoke to South America in just under 13h 59m. Your travel time can differ by up to 14h 27m. There are 2587 mi between Roanoke and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Roanoke to South America?

    The most popular route from Roanoke to South America is Roanoke - Rio de Janeiro–Galeão Intl. You may also consider Roanoke - Guayaquil Jose Joaquin de Olmedo or Roanoke - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from Roanoke to South America that include hotel bookings?

    Yes. In addition to deals on Roanoke to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to South America.

  • Can I find deals for business class flights from Roanoke to South America?

    Yes. Cheapflights offers flight deals from Roanoke to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to South America?

    Currently, July is the cheapest month in which you can book a flight from Roanoke to South America (average of $377). Flying from Roanoke to South America in December is currently the most expensive (average of $628). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Roanoke to South America

Discover the top airline that operate flights from Roanoke to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 19, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$662Average$973FlexibilityNo cancel feeOn-time81%

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