$749+ Cheap flights from Roanoke (ROA) to South America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — BOG
Oct 12 — Oct 191
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
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Best
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Cheapest flights from Roanoke to South AmericaExplore the most affordable flight options available from Roanoke to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
Explore the most affordable flight options available from Roanoke to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
This FlightHub deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
2 stops17h 00m
Sun 11/157:05 am -
2 stops17h 14m
Deal found 9/8![LATAM Airlines logo]()
$783
This Ovago deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:00 pm -
2 stops27h 30m
Tue 11/35:05 am -
2 stops30h 21m
Deal found 9/12![Copa Airlines logo]()
$957
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:26 am -
2 stops20h 24m
Mon 11/210:45 pm -
2 stops17h 30m
Deal found 9/11![United Airlines logo]()
$1,060
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
1 stop15h 25m
Sat 11/1412:55 am -
1 stop9h 43m
Deal found 9/8![Delta logo]()
$1,062
This LATAM Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:00 pm -
2 stops27h 00m
Fri 12/411:10 pm -
1 stop20h 32m
Deal found 9/11![LATAM Airlines logo]()
$1,075
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:15 am -
2 stops21h 10m
Fri 12/410:15 pm -
2 stops19h 19m
Deal found 9/8![American Airlines logo]()
$1,102
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/121:03 pm -
2 stops18h 07m
Mon 10/199:30 pm -
2 stops20h 48m
Deal found 9/11![American Airlines logo]()
$1,121
This LATAM Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:35 pm -
2 stops15h 27m
Wed 11/185:00 pm -
2 stops25h 14m
Deal found 9/7![LATAM Airlines logo]()
$1,137
This LATAM Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/123:32 pm -
1 stop15h 43m
Mon 10/198:55 pm -
2 stops18h 57m
Deal found 9/11![LATAM Airlines logo]()
$1,144
This lastminute.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:00 am -
2 stops24h 30m
Mon 11/28:25 pm -
3 stops27h 32m
Deal found 9/11![LATAM Airlines logo]()
$1,201
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:03 pm -
2 stops18h 17m
Fri 10/3011:55 pm -
2 stops18h 18m
Deal found 9/8![American Airlines logo]()
$1,207
This LATAM Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:13 am -
1 stop22h 02m
Fri 10/307:10 am -
2 stops18h 17m
Deal found 9/8![LATAM Airlines logo]()
$1,263
Best flights from Roanoke to South AmericaDiscover carefully curated flight deals from Roanoke to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
Discover carefully curated flight deals from Roanoke to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/510:35 am -
2 stops37h 55m
Sun 2/141:35 am -
2 stops35h 58m
Deal found 9/10![United Airlines logo]()
$749
This Orbitz deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
1 stop15h 25m
Sun 11/157:05 am -
2 stops17h 14m
Deal found 9/8![LATAM Airlines logo]()
$868
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/57:50 pm -
2 stops23h 02m
Sun 2/1412:55 am -
1 stop9h 39m
Deal found 9/10![Delta logo]()
$892
This Ovago deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:00 pm -
2 stops27h 30m
Tue 11/35:05 am -
2 stops30h 21m
Deal found 9/12![Copa Airlines logo]()
$957
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:15 am -
2 stops21h 10m
Fri 12/410:15 pm -
2 stops19h 19m
Deal found 9/8![American Airlines logo]()
$1,102
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/25:41 am -
2 stops18h 49m
Fri 2/51:35 am -
2 stops22h 57m
Deal found 9/8![United Airlines logo]()
$814
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
1 stop15h 25m
Sat 11/1412:55 am -
1 stop9h 43m
Deal found 9/8![Delta logo]()
$1,062
This LATAM Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
2 stops23h 30m
Fri 12/47:30 am -
2 stops18h 57m
Deal found 9/11![LATAM Airlines logo]()
$1,075
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:26 am -
2 stops20h 24m
Mon 11/210:45 pm -
2 stops17h 30m
Deal found 9/11![United Airlines logo]()
$1,060
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:03 pm -
2 stops18h 17m
Fri 10/3011:55 pm -
2 stops18h 18m
Deal found 9/8![American Airlines logo]()
$1,207
This LATAM Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:35 pm -
2 stops15h 27m
Wed 11/185:00 pm -
2 stops25h 14m
Deal found 9/7![LATAM Airlines logo]()
$1,137
This LATAM Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:13 am -
1 stop19h 27m
Mon 11/211:10 pm -
1 stop15h 23m
Deal found 9/11![LATAM Airlines logo]()
$1,144
This Expedia deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2911:20 am -
2 stops27h 20m
Sun 2/79:05 pm -
1 stop15h 29m
Deal found 9/12![LATAM Airlines logo]()
$1,202
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/295:41 am -
2 stops29h 29m
Sun 2/710:05 am -
2 stops29h 53m
Deal found 9/12![United Airlines logo]()
$1,393
This LATAM Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/47:50 pm -
1 stop12h 25m
Mon 3/89:05 pm -
1 stop15h 29m
Deal found 9/8![LATAM Airlines logo]()
$1,203
This LATAM Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/43:25 pm -
2 stops16h 00m
Mon 3/810:10 am -
2 stops30h 30m
Deal found 9/7![LATAM Airlines logo]()
$1,223
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/97:50 pm -
2 stops19h 10m
Sun 3/218:13 am -
2 stops27h 21m
Deal found 9/10![Delta logo]()
$1,865
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:13 am -
2 stops21h 12m
Tue 11/36:55 pm -
2 stops19h 38m
Deal found 9/12![Delta logo]()
$2,253
This Avianca deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/910:20 am -
2 stops17h 25m
Sun 3/214:15 pm -
2 stops18h 08m
Deal found 9/10![Multiple Airlines logo]()
$5,537
This BusinessClass deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/93:25 pm -
1 stop14h 15m
Sun 3/218:13 am -
2 stops27h 21m
Deal found 9/10![LATAM Airlines logo]()
$2,161
This Priceline deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:32 pm -
2 stops29h 28m
Fri 10/306:55 pm -
2 stops18h 38m
Deal found 9/8![LATAM Airlines logo]()
$3,427
Last-minute flights from Roanoke to South AmericaDiscover last-minute flight deals from Roanoke to South America. Data last updated September 12, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to South America. Data last updated September 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/121:03 pm -
2 stops18h 07m
Mon 10/199:30 pm -
2 stops20h 48m
Deal found 9/11![American Airlines logo]()
$1,121
This LATAM Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/123:32 pm -
1 stop15h 43m
Mon 10/198:55 pm -
2 stops18h 57m
Deal found 9/11![LATAM Airlines logo]()
$1,144
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:03 pm -
2 stops18h 17m
Fri 10/3011:55 pm -
2 stops18h 18m
Deal found 9/8![American Airlines logo]()
$1,207
This LATAM Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:13 am -
1 stop22h 02m
Fri 10/307:10 am -
2 stops18h 17m
Deal found 9/8![LATAM Airlines logo]()
$1,263
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:13 am -
1 stop22h 02m
Fri 10/309:05 pm -
1 stop16h 28m
Deal found 9/8![Delta logo]()
$1,379
This Priceline deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:32 pm -
2 stops29h 28m
Fri 10/306:55 pm -
2 stops18h 38m
Deal found 9/8![LATAM Airlines logo]()
$3,427
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:26 am -
2 stops20h 24m
Mon 11/210:45 pm -
2 stops17h 30m
Deal found 9/11![United Airlines logo]()
$1,060
This lastminute.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:00 am -
2 stops24h 30m
Mon 11/28:25 pm -
3 stops27h 32m
Deal found 9/11![LATAM Airlines logo]()
$1,201
This Ovago deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:00 pm -
2 stops27h 30m
Tue 11/35:05 am -
2 stops30h 21m
Deal found 9/12![Copa Airlines logo]()
$957
This Priceline deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:38 pm -
1 stop14h 37m
Tue 11/38:30 am -
2 stops30h 03m
Deal found 9/12![LATAM Airlines logo]()
$1,475
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:13 am -
2 stops21h 12m
Tue 11/36:55 pm -
2 stops19h 38m
Deal found 9/12![Delta logo]()
$2,253
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:40 am -
2 stops21h 55m
Tue 11/39:55 pm -
3 stops25h 06m
Deal found 9/12![United Airlines logo]()
$18,147
Find flight deals from Roanoke to South America
Keep the following information in mind while searching for Roanoke to South America flight deals. Data was last updated September 12, 2026.
Round-trip from | $749 (United Airlines) |
|---|
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
Use the filters below to find and compare flights from Roanoke to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeQuito
ROA Roanoke - UIO Quito Mariscal Sucr
ROAUIO
Roanoke
Tue 1/5
10:35 am-12:30 am
2 stops37h 55m
Quito Mariscal Sucr
Sun 2/14
1:35 am-1:33 pm
2 stops35h 58m
$749
RoanokeQuito
ROA Roanoke - UIO Quito Mariscal Sucr
ROAUIO
Roanoke
Tue 2/2
5:41 am-12:30 am
2 stops18h 49m
Quito Mariscal Sucr
Fri 2/5
1:35 am-12:32 am
2 stops22h 57m
$814
RoanokeQuito
ROA Roanoke - UIO Quito Mariscal Sucr
ROAUIO
Roanoke
Sun 11/8
6:00 am-9:25 pm
1 stop15h 25m
Quito Mariscal Sucr
Sun 11/15
7:05 am-12:19 am
2 stops17h 14m
$868
RoanokeQuito
ROA Roanoke - UIO Quito Mariscal Sucr
ROAUIO
Roanoke
Tue 1/5
7:50 pm-6:52 pm
2 stops23h 02m
Quito Mariscal Sucr
Sun 2/14
12:55 am-10:34 am
1 stop9h 39m
$892
RoanokeRio de Janeiro
ROA Roanoke - GIG Rio de Janeiro–Galeão Intl
ROAGIG
Roanoke
Tue 10/27
8:00 pm-12:30 am
2 stops27h 30m
Rio de Janeiro–Galeão Intl
Tue 11/3
5:05 am-9:26 am
2 stops30h 21m
$957
RoanokeSantiago
ROA Roanoke - SCL Santiago Arturo Merino Benitez
ROASCL
Roanoke
Mon 10/26
10:26 am-7:50 am
2 stops20h 24m
Santiago Arturo Merino Benitez
Mon 11/2
10:45 pm-2:15 pm
2 stops17h 30m
$1,060
Quickest round-trip
RoanokeQuito
ROA Roanoke - UIO Quito Mariscal Sucr
ROAUIO
Roanoke
Sun 11/8
6:00 am-9:25 pm
1 stop15h 25m
Quito Mariscal Sucr
Sat 11/14
12:55 am-10:38 am
1 stop9h 43m
$1,062
RoanokeSantiago
ROA Roanoke - SCL Santiago Arturo Merino Benitez
ROASCL
Roanoke
Fri 11/27
6:00 am-7:30 am
2 stops23h 30m
Santiago Arturo Merino Benitez
Fri 12/4
7:30 am-12:27 am
2 stops18h 57m
$1,075
RoanokeSantiago
ROA Roanoke - SCL Santiago Arturo Merino Benitez
ROASCL
Roanoke
Fri 11/27
10:15 am-9:25 am
2 stops21h 10m
Santiago Arturo Merino Benitez
Fri 12/4
10:15 pm-3:34 pm
2 stops19h 19m
$1,102
RoanokeGuayaquil
ROA Roanoke - GYE Guayaquil Jose Joaquin de Olmedo
ROAGYE
Roanoke
Sat 11/14
4:35 pm-8:02 am
2 stops15h 27m
Guayaquil Jose Joaquin de Olmedo
Wed 11/18
5:00 pm-6:14 pm
2 stops25h 14m
$1,137
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Roanoke to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Roanoke with our price prediction graph.
ROA-GIG
ROA-SCL
ROA-SDU
ROA-UIO
ROA-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to South America
ROA-0SA
ROA-GIG
ROA-SCL
ROA-SDU
ROA-UIO
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 12, 2026.
Read reviews from past customers who have flown LATAM Airlines from Roanoke to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Food
6.7
Entertainment
7.0
Overall
7.4
Crew
8.0
Comfort
7.3
Reviews
1 / 20
8.0
ExcellentNoah,Aug 2026
JFK - GRU
Boarding
7.5
Food
6.7
Entertainment
7.0
Overall
7.4
Crew
8.0
Comfort
7.3
Reviews
1 / 20
8.0
ExcellentNoah,Aug 2026
JFK - GRU
Related info for your journey
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Discover the top airline that operate flights from Roanoke to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$662 | Average$973 | FlexibilityNo cancel fee | On-time81% |