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South America

$422+ Cheap flights from Roanoke (ROA) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — BOG
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Cheap flight deals from Roanoke to South America

Keep the following information in mind while searching for Roanoke to South America flight deals. Data was last updated November 13, 2025.

Round-trip from

$787
(United Airlines)

One-way from

$422
(Ovago)
From Roanoke to South America
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One-way flight from Roanoke to South America
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Find flight deals from Roanoke to South America

Cheapest flights from Roanoke to South America
Explore the most affordable flight options available from Roanoke to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/155:05 amROA - GYE
2 stops18h 01mAmerican Airlines
Tue 11/186:00 amGYE - ROA
2 stops17h 53mAmerican Airlines
Deal found 11/12$457
This Avianca deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/157:50 pmROA - UIO
2 stops31h 00mAvianca
Mon 11/174:00 amUIO - ROA
2 stops14h 43mAvianca
Deal found 11/11$635
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1310:20 amROA - UIO
2 stops38h 10mUnited Airlines
Wed 12/178:00 amUIO - ROA
2 stops25h 57mUnited Airlines
Deal found 11/12$787
This LATAM Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:00 amROA - UIO
2 stops13h 05mLATAM Airlines
Tue 11/186:45 pmUIO - ROA
2 stops29h 30mLATAM Airlines
Deal found 11/11$793
This Avianca deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/157:50 pmROA - GYE
2 stops37h 25mAvianca
Mon 11/173:30 amGYE - ROA
2 stops15h 13mAvianca
Deal found 11/11$822
This Expedia deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/133:50 pmROA - UIO
2 stops37h 27mLATAM Airlines
Wed 12/1711:45 pmUIO - ROA
1 stop19h 30mLATAM Airlines
Deal found 11/12$827
This Ovago deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1311:20 amROA - GYE
2 stops19h 33mLATAM Airlines
Mon 1/197:13 pmGYE - ROA
2 stops15h 31mLATAM Airlines
Deal found 11/12$958
This Ovago deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:00 amROA - GYE
2 stops26h 33mLATAM Airlines
Sun 1/185:31 pmGYE - ROA
2 stops25h 48mLATAM Airlines
Deal found 11/13$977
This Ovago deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:00 amROA - UIO
1 stop14h 00mLATAM Airlines
Fri 1/1611:45 pmUIO - ROA
1 stop10h 59mLATAM Airlines
Deal found 11/13$982
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:00 amROA - UIO
1 stop12h 55mDelta
Mon 11/1712:55 amUIO - ROA
1 stop9h 45mDelta
Deal found 11/11$1,095
This LATAM Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:00 amROA - SCL
1 stop22h 10mLATAM Airlines
Sat 12/2010:35 amSCL - ROA
2 stops15h 32mLATAM Airlines
Deal found 11/11$1,139
This United deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1310:20 amROA - GYE
2 stops31h 16mMultiple Airlines
Sun 1/183:30 amGYE - ROA
2 stops34h 39mMultiple Airlines
Deal found 11/11$1,593

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Roanoke to South America that are best for you.

Fly from

Roanoke

Fly to

South America

Route

Depart

Return

Price

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Sat 12/13

10:20 am-12:30 am

2 stops38h 10m

Quito Mariscal Sucr

Wed 12/17

8:00 am-9:57 am

2 stops25h 57m

$787

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Sat 12/13

3:50 pm-5:17 am

2 stops37h 27m

Quito Mariscal Sucr

Wed 12/17

11:45 pm-7:15 pm

1 stop19h 30m

$827

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Thu 1/1

6:00 am-9:25 pm

1 stop15h 25m

Quito Mariscal Sucr

Mon 1/12

6:45 pm-12:06 am

2 stops29h 21m

$933

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

Sat 12/13

6:00 am-6:53 am

2 stops24h 53m

Guayaquil Jose Joaquin de Olmedo

Mon 1/19

3:20 pm-10:44 am

2 stops19h 24m

$958

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

Sat 12/13

6:00 am-8:33 am

2 stops26h 33m

Guayaquil Jose Joaquin de Olmedo

Sun 1/18

5:31 pm-7:19 pm

2 stops25h 48m

$977

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Thu 12/18

6:00 am-8:00 pm

1 stop14h 00m

Quito Mariscal Sucr

Fri 1/16

11:45 pm-10:44 am

1 stop10h 59m

$982

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Thu 1/1

6:00 am-9:25 pm

1 stop15h 25m

Quito Mariscal Sucr

Mon 1/12

7:00 pm-1:40 pm

2 stops18h 40m

$1,014

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Mon 12/15

6:00 am-6:10 am

1 stop22h 10m

Santiago Arturo Merino Benitez

Sat 12/20

10:35 am-12:07 am

2 stops15h 32m

$1,139

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Thu 12/18

6:00 am-5:17 am

2 stops23h 17m

Quito Mariscal Sucr

Sat 1/17

7:00 pm-11:06 pm

2 stops28h 06m

$1,144

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Sat 3/21

3:25 pm-2:10 pm

2 stops21h 45m

Rio de Janeiro–Galeão Intl

Wed 3/25

7:15 am-2:39 pm

2 stops32h 24m

$1,181

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Showing 1-10 of 18 results
1
2

Best time to book a flight from Roanoke to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to South America

What is the cheapest month to book a flight from Roanoke to South America?

Currently, April is the cheapest month in which you can book a flight from Roanoke to South America (average of $302). Flying from Roanoke to South America in October is currently the most expensive (average of $662). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to SA?

Find hourly flight availability from Roanoke to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

A simple way to save on the total cost of your ticket is to fly from Roanoke to South America in the morning. If you’re flexible enough to do this you can expect to save up to 43% on your trip compared to booking a flight at noon.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated November 13, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Roanoke to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,007 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to South America?

    Most people fly from Roanoke (ROA) if they book a flight from Roanoke to South America. Roanoke is conveniently located just 4.2 mi from Roanoke’s city center.

  • How long is the flight from Roanoke to South America?

    United Airlines, LATAM Airlines, and Delta can get you from Roanoke to South America in just under 21h 45m. Your travel time can differ by up to 16h 25m. There are 4789 mi between Roanoke and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Roanoke to South America?

    The most popular route from Roanoke to South America is Roanoke - Quito Mariscal Sucr. You may also consider Roanoke - Guayaquil Jose Joaquin de Olmedo or Roanoke - Rio de Janeiro Santos Dumont.

  • Can I find deals for flights from Roanoke to South America that include hotel bookings?

    Yes. In addition to deals on Roanoke to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to South America.

  • Can I find deals for business class flights from Roanoke to South America?

    Yes. Cheapflights offers flight deals from Roanoke to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to South America?

    Currently, April is the cheapest month in which you can book a flight from Roanoke to South America (average of $302). Flying from Roanoke to South America in October is currently the most expensive (average of $662). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Roanoke to South America

Discover the top 2 airlines that operate flights from Roanoke to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$410Average$484FlexibilityNo cancel feeOn-time71%
DeltaCheapest$501Average$769FlexibilityNo cancel feeOn-timeN/A

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