South America

$701+ Cheap flights from Roanoke (ROA) to South America

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/21. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — BOG
Aug 25 — Sep 11
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Cheap flight deals from Roanoke to South America

Keep the following information in mind while searching for Roanoke to South America flight deals. Data was last updated August 20, 2025.

Round-trip from

$738
(Delta)
From Roanoke to South America

Find flight deals from Roanoke to South America

Cheapest flights from Roanoke to South America
Explore the most affordable flight options available from Roanoke to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/216:00 amROA - UIO
2 stops14h 05mDelta
Thu 8/289:11 amUIO - ROA
2 stops14h 21mDelta
Deal found 8/19$701
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:59 pmROA - UIO
2 stops23h 06mDelta
Mon 11/1012:55 amUIO - ROA
1 stop9h 38mDelta
Deal found 8/18$738
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:20 amROA - UIO
2 stops18h 10mUnited Airlines
Mon 11/101:35 amUIO - ROA
2 stops12h 37mUnited Airlines
Deal found 8/18$752
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/67:55 amROA - GYE
2 stops12h 15mAmerican Airlines
Wed 10/88:15 amGYE - ROA
2 stops25h 27mAmerican Airlines
Deal found 8/17$801
This LATAM Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/83:30 pmROA - SCL
2 stops20h 35mLATAM Airlines
Fri 12/1211:15 pmSCL - ROA
1 stop13h 18mLATAM Airlines
Deal found 8/18$814
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:00 amROA - UIO
2 stops14h 57mAmerican Airlines
Tue 11/118:27 amUIO - ROA
2 stops13h 09mAmerican Airlines
Deal found 8/18$860
This Expedia deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/13:30 pmROA - SCL
3 stops21h 00mLATAM Airlines
Sat 12/66:40 amSCL - ROA
2 stops19h 09mLATAM Airlines
Deal found 8/17$1,018
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/16:20 amROA - GYE
2 stops29h 55mUnited Airlines
Sun 9/78:32 amGYE - ROA
2 stops24h 34mUnited Airlines
Deal found 8/18$1,026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Roanoke to South America that are best for you.

Fly from

Roanoke

Fly to

South America

Route

Depart

Return

Price

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Sat 11/8

7:59 pm-7:05 pm

2 stops23h 06m

Quito Mariscal Sucr

Mon 11/10

12:55 am-10:33 am

1 stop9h 38m

$738

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Sat 11/8

6:45 am-12:30 am

2 stops17h 45m

Quito Mariscal Sucr

Mon 11/10

1:35 am-2:12 pm

2 stops12h 37m

$752

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

Mon 10/6

7:55 am-7:10 pm

2 stops12h 15m

Guayaquil Jose Joaquin de Olmedo

Wed 10/8

8:15 am-10:42 am

2 stops25h 27m

$801

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Mon 12/1

11:20 am-6:40 am

2 stops17h 20m

Santiago Arturo Merino Benitez

Fri 12/5

4:35 am-11:49 pm

2 stops21h 14m

$814

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Mon 12/8

11:20 am-6:25 am

2 stops17h 05m

Santiago Arturo Merino Benitez

Fri 12/12

9:30 pm-10:33 am

1 stop15h 03m

$814

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

Mon 9/1

6:20 am-11:15 am

2 stops29h 55m

Guayaquil Jose Joaquin de Olmedo

Sun 9/7

8:32 am-10:06 am

2 stops24h 34m

$1,026

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Mon 9/15

11:15 am-6:10 am

2 stops17h 55m

$753

RoanokeRio de Janeiro

ROA - SDU

ROASDU

Roanoke

Mon 9/15

2:50 pm-2:20 pm

2 stops22h 30m

$839

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Mon 9/15

6:20 am-1:50 pm

3 stops30h 30m

$1,891

RoanokeRio de Janeiro

ROA - SDU

ROASDU

Roanoke

Mon 9/15

6:20 am-2:20 pm

3 stops31h 00m

$1,891

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/19

Best time to book a flight from Roanoke to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to South America

What is the cheapest month to book a flight from Roanoke to South America?

Currently, May is the cheapest month in which you can book a flight from Roanoke to South America (average of $359). Flying from Roanoke to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to SA?

Find hourly flight availability from Roanoke to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Roanoke to South America as you normally would.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated August 20, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Roanoke to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Comfort

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Comfort

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Comfort

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Roanoke to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Roanoke to South America?

    Most people fly from Roanoke (ROA) if they book a flight from Roanoke to South America. Roanoke is conveniently located just 4.2 mi from Roanoke’s city center.

  • How long is the flight from Roanoke to South America?

    Delta, United Airlines, and American Airlines can get you from Roanoke to South America in just under 12h 15m. Your travel time can differ by up to 10h 51m. There are 2726 mi between Roanoke and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Roanoke to South America one-way?

    The cheapest airlines for a one-way flight from Roanoke to South America are Delta ($753), United Airlines ($839), and Air Canada ($1,891).

  • What are the most popular routes from Roanoke to South America?

  • Can I find deals for flights from Roanoke to South America that include hotel bookings?

    Yes. In addition to deals on Roanoke to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to South America.

  • Can I find deals for business class flights from Roanoke to South America?

    Yes. Cheapflights offers flight deals from Roanoke to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to South America?

    Currently, May is the cheapest month in which you can book a flight from Roanoke to South America (average of $359). Flying from Roanoke to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Roanoke to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Roanoke to South America

Discover the top 2 airlines that operate flights from Roanoke to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$410Average$484FlexibilityNo cancel feeOn-time71%
DeltaCheapest$501Average$755FlexibilityNo cancel feeOn-timeN/A

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