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South America

$569+ Cheap flights from Roanoke (ROA) to South America

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/12. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — BOG
nov. 22 — nov. 291
sáb. 11/22
sáb. 11/29
1 adult, Economy
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Cheap flight deals from Roanoke to South America

Keep the following information in mind while searching for Roanoke to South America flight deals. Data was last updated octubre 23, 2025.

Round-trip from

$569
(United Airlines)
From Roanoke to South America
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Find flight deals from Roanoke to South America

Cheapest flights from Roanoke to South America
Explore the most affordable flight options available from Roanoke to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 23, 2025.

This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/157:35 amROA - GYE
2 stops39h 31mAmerican Airlines
mar. 11/186:00 amGYE - ROA
2 stops27h 45mAmerican Airlines
Deal found 10/20$587
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/610:20 amROA - SCL
2 stops20h 30mUnited Airlines
sáb. 12/1310:45 pmSCL - ROA
2 stops17h 24mUnited Airlines
Deal found 10/22$799
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/86:45 amROA - UIO
2 stops17h 45mUnited Airlines
lun. 11/101:35 amUIO - ROA
2 stops15h 21mUnited Airlines
Deal found 10/21$847
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/86:00 amROA - UIO
1 stop12h 55mDelta
lun. 11/1012:55 amUIO - ROA
1 stop9h 45mDelta
Deal found 10/20$913
This LATAM Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/86:00 amROA - UIO
1 stop12h 55mLATAM Airlines
lun. 11/1012:55 amUIO - ROA
1 stop9h 45mLATAM Airlines
Deal found 10/21$921
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/88:25 amROA - UIO
2 stops14h 39mAmerican Airlines
mar. 11/118:27 amUIO - ROA
2 stops13h 09mAmerican Airlines
Deal found 10/21$1,034
This LATAM Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/206:00 amROA - SCL
1 stop23h 40mLATAM Airlines
mar. 1/206:40 amSCL - ROA
2 stops19h 09mLATAM Airlines
Deal found 10/22$1,036
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/811:20 amROA - SCL
1 stop18h 20mDelta
vie. 12/1211:10 pmSCL - ROA
1 stop13h 30mDelta
Deal found 10/22$1,114
This LATAM Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/86:00 amROA - SCL
2 stops21h 35mLATAM Airlines
vie. 12/127:15 amSCL - ROA
3 stops18h 56mLATAM Airlines
Deal found 10/22$1,119
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/207:55 pmROA - SCL
2 stops58h 55mUnited Airlines
mar. 1/2010:45 pmSCL - ROA
2 stops17h 24mUnited Airlines
Deal found 10/22$1,303
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/710:20 amROA - SDU
2 stops28h 15mUnited Airlines
dom. 12/142:50 pmSDU - ROA
2 stops21h 16mUnited Airlines
Deal found 10/23$1,323
This Avianca deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/157:50 pmROA - GYE
2 stops37h 25mAvianca
lun. 11/174:40 amGYE - ROA
2 stops14h 03mAvianca
Deal found 10/22$3,127

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 23, 2025.
Use the filters below to find and compare flights from Roanoke to South America that are best for you.

Fly from

Roanoke

Fly to

South America

Route

Depart

Return

Price

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

dom. 4/12

8:00 pm-11:25 pm

2 stops28h 25m

Quito Mariscal Sucr

dom. 4/19

12:35 am-8:39 pm

2 stops19h 04m

$569

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

sáb. 11/15

7:35 am-11:06 pm

2 stops39h 31m

Guayaquil Jose Joaquin de Olmedo

mar. 11/18

6:00 am-9:45 am

2 stops27h 45m

$587

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

dom. 4/12

7:50 pm-8:09 pm

1 stop25h 19m

Quito Mariscal Sucr

lun. 4/20

9:11 am-11:49 pm

2 stops13h 38m

$654

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

vie. 3/13

11:20 am-8:35 pm

1 stop10h 15m

Quito Mariscal Sucr

dom. 3/22

11:45 pm-10:33 am

1 stop9h 48m

$763

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

vie. 3/13

7:00 am-5:17 am

2 stops23h 17m

Quito Mariscal Sucr

dom. 3/22

7:00 pm-10:33 am

2 stops14h 33m

$774

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

sáb. 12/6

10:20 am-8:50 am

2 stops20h 30m

Santiago Arturo Merino Benitez

sáb. 12/13

10:45 pm-2:09 pm

2 stops17h 24m

$799

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

sáb. 11/8

6:45 am-12:30 am

2 stops17h 45m

Quito Mariscal Sucr

lun. 11/10

1:35 am-2:12 pm

2 stops12h 37m

$847

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

sáb. 12/20

6:00 am-7:40 am

1 stop23h 40m

Santiago Arturo Merino Benitez

mar. 1/20

6:40 am-11:49 pm

2 stops19h 09m

$1,036

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

lun. 12/8

3:50 pm-7:40 am

1 stop13h 50m

Santiago Arturo Merino Benitez

jue. 12/11

4:35 am-12:11 am

2 stops21h 36m

$1,114

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

lun. 12/8

3:50 pm-2:05 pm

2 stops20h 15m

Santiago Arturo Merino Benitez

vie. 12/12

8:10 am-12:11 am

2 stops18h 01m

$1,114

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/21

Showing 1-10 of 15 results
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Best time to book a flight from Roanoke to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to South America

What is the cheapest month to book a flight from Roanoke to South America?

Currently, April is the cheapest month in which you can book a flight from Roanoke to South America (average of $302). Flying from Roanoke to South America in October is currently the most expensive (average of $662). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to SA?

Find hourly flight availability from Roanoke to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 23, 2025.

A simple way to save on the total cost of your ticket is to fly from Roanoke to South America in the morning. If you’re flexible enough to do this you can expect to save up to 35% on your trip compared to booking a flight at noon.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated octubre 23, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Roanoke to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,982 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,982 reviews
Delta
7.9
Good
7,982 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,982 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to South America?

    Most people fly from Roanoke (ROA) if they book a flight from Roanoke to South America. Roanoke is conveniently located just 4.2 mi from Roanoke’s city center.

  • How long is the flight from Roanoke to South America?

    United Airlines, American Airlines, and Delta can get you from Roanoke to South America in just under 25h 19m. Your travel time can differ by up to 14h 12m. There are 2587 mi between Roanoke and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Roanoke to South America?

    The most popular route from Roanoke to South America is Roanoke - Santiago Arturo Merino Benitez. You may also consider Roanoke - Quito Mariscal Sucr or Roanoke - Guayaquil Jose Joaquin de Olmedo.

  • Can I find deals for flights from Roanoke to South America that include hotel bookings?

    Yes. In addition to deals on Roanoke to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to South America.

  • Can I find deals for business class flights from Roanoke to South America?

    Yes. Cheapflights offers flight deals from Roanoke to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to South America?

    Currently, April is the cheapest month in which you can book a flight from Roanoke to South America (average of $302). Flying from Roanoke to South America in October is currently the most expensive (average of $662). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Roanoke to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Roanoke to South America

Discover the top 2 airlines that operate flights from Roanoke to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$410Average$484FlexibilityNo cancel feeOn-time71%
DeltaCheapest$501Average$769FlexibilityNo cancel feeOn-timeN/A

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