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South America

$434+ Cheap flights from Roanoke (ROA) to South America

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — BOG
Mar 14 — Mar 211
Sat 3/14
Sat 3/21
1 adult, Economy
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Cheap flight deals from Roanoke to South America

Cheapest flights from Roanoke to South America
Explore the most affordable flight options available from Roanoke to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.

This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:04 pm
ROA
-
GYE
2 stops20h 26m
American Airlines
Mon 3/162:30 pm
GYE
-
ROA
2 stops20h 04m
American Airlines
Deal found 2/10$434
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/138:00 pm
ROA
-
GYE
2 stops18h 30m
American Airlines
Tue 2/173:30 pm
GYE
-
ROA
2 stops20h 04m
American Airlines
Deal found 2/9$638
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/510:51 am
ROA
-
UIO
2 stops13h 34m
United Airlines
Thu 5/712:35 am
UIO
-
ROA
2 stops12h 38m
United Airlines
Deal found 2/8$726
This LATAM Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:28 pm
ROA
-
UIO
2 stops14h 15m
LATAM Airlines
Fri 5/86:50 pm
UIO
-
ROA
2 stops18h 49m
LATAM Airlines
Deal found 2/11$758
This LATAM Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/113:13 pm
ROA
-
SCL
1 stop15h 27m
LATAM Airlines
Sat 4/48:45 pm
SCL
-
ROA
2 stops18h 48m
LATAM Airlines
Deal found 2/10$860
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:20 am
ROA
-
GYE
2 stops36h 15m
United Airlines
Wed 10/2812:20 pm
GYE
-
ROA
2 stops21h 12m
United Airlines
Deal found 2/8$972
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/167:00 am
ROA
-
GIG
2 stops21h 05m
Delta
Thu 12/317:00 am
GIG
-
ROA
2 stops18h 49m
Delta
Deal found 2/10$1,012
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/167:00 am
ROA
-
GIG
2 stops21h 05m
Delta
Fri 1/17:00 am
GIG
-
ROA
2 stops18h 49m
Delta
Deal found 2/10$1,052
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/167:00 am
ROA
-
GIG
2 stops21h 05m
Delta
Tue 1/57:00 am
GIG
-
ROA
2 stops18h 49m
Delta
Deal found 2/10$1,062
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/217:00 am
ROA
-
GIG
2 stops31h 30m
Delta
Wed 12/307:00 am
GIG
-
ROA
2 stops18h 49m
Delta
Deal found 2/10$1,069
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:00 am
ROA
-
GIG
2 stops32h 20m
Delta
Wed 12/307:00 am
GIG
-
ROA
2 stops18h 49m
Delta
Deal found 2/10$1,102
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/217:00 am
ROA
-
GIG
2 stops45h 05m
Delta
Fri 1/17:00 am
GIG
-
ROA
2 stops18h 49m
Delta
Deal found 2/10$1,109

Find flight deals from Roanoke to South America

Keep the following information in mind while searching for Roanoke to South America flight deals. Data was last updated February 12, 2026.

Round-trip from

$434
(American Airlines)
From Roanoke to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Roanoke to South America that are best for you.

Fly from

Roanoke

Fly to

South America

Route

Depart

Return

Price

RoanokeGuayaquil

ROA - GYE

ROAGYE

Roanoke

Thu 3/5

6:04 pm-2:30 pm

2 stops20h 26m

Guayaquil Jose Joaquin de Olmedo

Mon 3/16

2:30 pm-11:34 am

2 stops20h 04m

$434

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Tue 5/5

10:51 am-11:25 pm

2 stops13h 34m

Quito Mariscal Sucr

Thu 5/7

12:35 am-2:13 pm

2 stops12h 38m

$726

RoanokeQuito

ROA - UIO

ROAUIO

Roanoke

Tue 5/5

3:28 pm-4:43 am

2 stops14h 15m

Quito Mariscal Sucr

Fri 5/8

6:50 pm-2:39 pm

2 stops18h 49m

$758

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Wed 3/11

3:13 pm-7:40 am

1 stop15h 27m

Santiago Arturo Merino Benitez

Sat 4/4

8:45 pm-2:33 pm

2 stops18h 48m

$860

RoanokeRio de Janeiro

ROA - SDU

ROASDU

Roanoke

Thu 5/21

6:15 am-4:45 pm

2 stops33h 30m

Rio de Janeiro Santos Dumont

Sat 5/30

5:30 pm-9:46 am

2 stops17h 16m

$1,238

RoanokeRio de Janeiro

ROA - SDU

ROASDU

Roanoke

Thu 3/19

10:43 am-4:45 pm

2 stops29h 02m

Rio de Janeiro Santos Dumont

Mon 3/23

1:50 pm-9:43 am

2 stops20h 53m

$1,491

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Thu 5/21

6:15 am-8:15 am

2 stops49h 00m

Rio de Janeiro–Galeão Intl

Sat 5/30

9:05 pm-9:46 am

2 stops37h 41m

$1,564

RoanokeRio de Janeiro

ROA - GIG

ROAGIG

Roanoke

Thu 5/21

11:10 am-10:45 am

2 stops22h 35m

Rio de Janeiro–Galeão Intl

Sat 5/30

9:00 pm-10:30 am

1 stop14h 30m

$6,148

RoanokeSantiago

ROA - SCL

ROASCL

Roanoke

Fri 3/27

10:30 am-7:50 am

2 stops20h 20m

Santiago Arturo Merino Benitez

Thu 4/2

1:46 am-1:29 pm

2 stops36h 43m

$6,902

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/10

Best time to book a flight from Roanoke to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to South America

What is the cheapest month to book a flight from Roanoke to South America?

Currently, April is the cheapest month in which you can book a flight from Roanoke to South America (average of $300). Flying from Roanoke to South America in December is currently the most expensive (average of $628). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated February 12, 2026.
Read reviews from past customers who have flown Delta, LATAM Airlines, and American Airlines from Roanoke to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,191 reviews

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,191 reviews
Delta
7.9
Good
8,191 reviews

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,920 reviews
Delta
7.9
Good
8,191 reviews

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,277 reviews
Delta
7.9
Good
8,191 reviews

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to South America?

    Most people fly from Roanoke (ROA) if they book a flight from Roanoke to South America. Roanoke is conveniently located just 4.2 mi from Roanoke’s city center.

  • How long is the flight from Roanoke to South America?

    American Airlines, United Airlines, and LATAM Airlines can get you from Roanoke to South America in just under 13h 34m. Your travel time can differ by up to 6h 52m. There are 2587 mi between Roanoke and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Roanoke to South America?

    The most popular route from Roanoke to South America is Roanoke - Rio de Janeiro Santos Dumont. You may also consider Roanoke - Rio de Janeiro–Galeão Intl or Roanoke - Guayaquil Jose Joaquin de Olmedo.

  • Can I find deals for flights from Roanoke to South America that include hotel bookings?

    Yes. In addition to deals on Roanoke to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to South America.

  • Can I find deals for business class flights from Roanoke to South America?

    Yes. Cheapflights offers flight deals from Roanoke to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to South America?

    Currently, April is the cheapest month in which you can book a flight from Roanoke to South America (average of $300). Flying from Roanoke to South America in December is currently the most expensive (average of $628). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Roanoke to South America

Discover the top 2 airlines that operate flights from Roanoke to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$746Average$829FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$857Average$973FlexibilityNo cancel feeOn-time81%

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