What are the cheapest airlines to fly from Washington, D.C. Reagan-National Airport to South America one-way?

$123 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on American Airlines and JetBlue, with prices starting from $128 and $130, respectively.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

What are the most popular routes from Washington, D.C. Reagan-National Airport to South America?

The most popular route from Washington, D.C. Reagan-National Airport to South America is Washington, D.C. Reagan-National - Lima J Chavez Intl. You may also consider Washington, D.C. Reagan-National - Bogotá El Dorado or Washington, D.C. Reagan-National - Buenos Aires Ministro Pistarini.

What are the most popular airlines that fly from Washington, D.C. Reagan-National Airport to South America?

The most popular airlines flying from Washington, D.C. Reagan-National Airport to South America are American Airlines, LATAM Airlines and Delta. Something to consider prior to booking your flight.

Can I find deals for flights from Reagan-National to South America that include hotel bookings?

Yes. In addition to deals on Reagan-National to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Reagan-National to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Reagan-National to South America.

Can I find deals for business class flights from Reagan-National to South America?

Yes. Cheapflights offers flight deals from Reagan-National to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$123+ Flights from Washington, D.C. Reagan-National Airport to South America

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Find flight deals from Reagan-National to South America

Cheapest flights from Reagan-National to South America
Explore the most affordable flight options available from Reagan-National to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

Mon 11/1710:10 pmDCA - CTG

2 stops15h 16mAmerican Airlines

Thu 11/204:30 pmCTG - DCA

2 stops16h 44mAmerican Airlines

Deal found 10/16

$301

Wed 10/296:00 amDCA - MDE

1 stop16h 05mUnited Airlines

Wed 11/510:45 amMDE - DCA

1 stop12h 59mUnited Airlines

Deal found 10/14

$303

Wed 11/1212:25 pmDCA - MDE

2 stops11h 14mAmerican Airlines

Sat 11/157:00 amMDE - DCA

1 stop17h 24mAmerican Airlines

Deal found 10/15

$308

Thu 11/67:59 pmDCA - MDE

1 stop26h 06mUnited Airlines

Wed 11/1210:45 amMDE - DCA

1 stop10h 00mUnited Airlines

Deal found 10/14

$310

Tue 12/25:59 amDCA - CTG

1 stop7h 27mAmerican Airlines

Tue 12/164:30 pmCTG - DCA

1 stop16h 28mAmerican Airlines

Deal found 10/16

$311

Sat 11/87:50 pmDCA - CTG

2 stops17h 36mAmerican Airlines

Tue 11/114:30 pmCTG - DCA

2 stops16h 44mAmerican Airlines

Deal found 10/14

$316

Sat 11/296:00 amDCA - MDE

1 stop16h 05mUnited Airlines

Fri 12/51:15 amMDE - DCA

1 stop17h 45mUnited Airlines

Deal found 10/15

$330

Sat 11/812:50 pmDCA - MDE

1 stop9h 15mUnited Airlines

Mon 12/151:15 amMDE - DCA

1 stop10h 17mUnited Airlines

Deal found 10/14

$334

Tue 10/282:51 pmDCA - MDE

1 stop31h 14mUnited Airlines

Tue 11/410:45 amMDE - DCA

1 stop12h 59mUnited Airlines

Deal found 10/15

$341

Wed 10/152:56 pmDCA - MDE

1 stop31h 14mUnited Airlines

Wed 10/229:45 amMDE - DCA

1 stop13h 05mUnited Airlines

Deal found 10/14

$342

Mon 11/310:20 amDCA - BOG

1 stop9h 10mLATAM Airlines

Thu 11/68:35 amBOG - DCA

1 stop13h 30mLATAM Airlines

Deal found 10/14

$343

Fri 11/78:59 amDCA - BOG

1 stop10h 31mDelta

Thu 11/139:00 amBOG - DCA

1 stop8h 26mDelta

Deal found 10/15

$353

Best flights from Reagan-National to South America
Discover carefully curated flight deals from Reagan-National to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 16, 2025.

Fri 11/78:15 amDCA - MDE

1 stop13h 50mUnited Airlines

Wed 11/1210:45 amMDE - DCA

1 stop10h 00mUnited Airlines

Deal found 10/15

$303

Wed 11/1212:25 pmDCA - MDE

2 stops11h 14mAmerican Airlines

Sat 11/157:00 amMDE - DCA

1 stop17h 24mAmerican Airlines

Deal found 10/15

$308

Wed 10/297:59 amDCA - BOG

1 stop12h 31mDelta

Wed 11/129:00 amBOG - DCA

1 stop12h 49mDelta

Deal found 10/13

$353

Thu 12/1110:20 amDCA - LIM

1 stop11h 00mMultiple Airlines

Fri 12/263:55 pmLIM - DCA

2 stops29h 01mMultiple Airlines

Deal found 10/15

$425

Wed 10/2912:50 pmDCA - MDE

1 stop9h 15mUnited Airlines

Sat 11/19:45 amMDE - DCA

1 stop10h 00mUnited Airlines

Deal found 10/15

$303

Wed 10/298:15 amDCA - MDE

1 stop13h 50mUnited Airlines

Wed 11/510:45 amMDE - DCA

1 stop10h 00mUnited Airlines

Deal found 10/15

$303

Tue 10/216:00 amDCA - GRU

2 stops26h 15mAir Canada

Tue 11/119:30 pmGRU - DCA

1 stop24h 15mAir Canada

Deal found 10/16

$671

Sun 10/267:00 amDCA - BOG

1 stop13h 30mDelta

Thu 10/306:35 pmBOG - DCA

2 stops15h 56mDelta

Deal found 10/14

$353

Thu 11/67:59 pmDCA - MDE

1 stop26h 06mUnited Airlines

Wed 11/1210:45 amMDE - DCA

1 stop10h 00mUnited Airlines

Deal found 10/14

$310

Wed 10/292:40 pmDCA - SDU

2 stops17h 45mLATAM Airlines

Wed 11/58:05 pmSDU - DCA

2 stops16h 01mLATAM Airlines

Deal found 10/15

$770

Wed 11/56:00 amDCA - BOG

1 stop8h 25mDelta

Wed 11/129:00 amBOG - DCA

1 stop8h 26mDelta

Deal found 10/15

$353

Fri 2/610:10 pmDCA - CTG

2 stops15h 20mAmerican Airlines

Wed 2/114:30 pmCTG - DCA

1 stop16h 28mAmerican Airlines

Deal found 10/13

$391

Wed 4/18:30 pmDCA - BOG

1 stop18h 05mDelta

Thu 4/238:35 amBOG - DCA

1 stop12h 37mDelta

Deal found 10/13

$353

Sat 11/296:00 amDCA - MDE

1 stop16h 05mUnited Airlines

Sat 12/610:45 amMDE - DCA

1 stop10h 11mUnited Airlines

Deal found 10/15

$330

Fri 2/66:00 amDCA - CTG

1 stop8h 15mDelta

Wed 2/113:30 pmCTG - DCA

1 stop7h 50mDelta

Deal found 10/13

$356

Thu 11/63:50 pmDCA - VCP

1 stop24h 55mAzul

Sun 11/911:20 pmVCP - DCA

1 stop25h 09mAzul

Deal found 10/14

$951

Tue 11/185:15 pmDCA - VCP

2 stops15h 30mGOL

Fri 11/289:50 amVCP - DCA

2 stops26h 53mGOL

Deal found 10/14

$967

Sat 11/812:50 pmDCA - MDE

1 stop9h 15mUnited Airlines

Tue 12/1610:45 amMDE - DCA

1 stop11h 19mUnited Airlines

Deal found 10/14

$334

Sun 2/86:00 amDCA - CTG

1 stop8h 15mDelta

Fri 2/133:30 pmCTG - DCA

1 stop7h 50mDelta

Deal found 10/15

$356

Fri 11/78:15 amDCA - BOG

1 stop14h 20mUnited Airlines

Mon 11/108:15 amBOG - DCA

1 stop10h 27mUnited Airlines

Deal found 10/15

$353

Tue 3/177:00 amDCA - CTG

2 stops18h 31mDelta

Thu 3/192:30 pmCTG - DCA

1 stop17h 44mDelta

Deal found 10/15

$362

Mon 11/312:50 pmDCA - BOG

1 stop9h 45mUnited Airlines

Wed 11/51:30 amBOG - DCA

1 stop9h 59mUnited Airlines

Deal found 10/14

$353

Sat 11/294:10 pmDCA - GRU

1 stop14h 50mAir Canada

Tue 12/99:45 pmGRU - DCA

1 stop19h 46mAir Canada

Deal found 10/14

$681

Mon 2/98:15 amDCA - BOG

1 stop14h 20mUnited Airlines

Thu 2/121:30 amBOG - DCA

1 stop10h 05mUnited Airlines

Deal found 10/14

$353

Fri 12/54:15 pmDCA - LIM

1 stop12h 45mDelta

Sun 12/1411:40 pmLIM - DCA

1 stop15h 20mDelta

Deal found 10/14

$425

Mon 11/178:15 amDCA - BOG

1 stop14h 20mUnited Airlines

Sat 11/228:15 amBOG - DCA

1 stop12h 30mUnited Airlines

Deal found 10/15

$353

Thu 11/135:58 pmDCA - GRU

1 stop12h 07mAmerican Airlines

Tue 11/2512:15 amGRU - DCA

1 stop20h 45mAmerican Airlines

Deal found 10/16

$751

Thu 11/2710:20 amDCA - LIM

1 stop18h 40mDelta

Wed 12/38:00 amLIM - DCA

1 stop14h 08mDelta

Deal found 10/13

$425

Sun 2/14:28 pmDCA - BOG

1 stop12h 42mUnited Airlines

Sun 2/88:15 amBOG - DCA

1 stop12h 41mUnited Airlines

Deal found 10/14

$353

Mon 10/277:59 pmDCA - VCP

1 stop20h 46mMultiple Airlines

Thu 11/65:55 pmVCP - DCA

2 stops29h 19mMultiple Airlines

Deal found 10/14

$856

Last-minute flights from Reagan-National to South America
Discover last-minute flight deals from Reagan-National to South America. Data last updated October 16, 2025 and is based on user searches.

Tue 10/282:51 pmDCA - MDE

1 stop31h 14mUnited Airlines

Tue 11/410:45 amMDE - DCA

1 stop12h 59mUnited Airlines

Deal found 10/15

$341

Wed 10/298:15 amDCA - MDE

1 stop13h 50mUnited Airlines

Wed 11/510:45 amMDE - DCA

1 stop10h 00mUnited Airlines

Deal found 10/15

$303

Mon 11/310:20 amDCA - BOG

1 stop9h 10mLATAM Airlines

Thu 11/68:35 amBOG - DCA

1 stop13h 30mLATAM Airlines

Deal found 10/14

$343

Thu 11/67:59 pmDCA - MDE

1 stop26h 06mUnited Airlines

Wed 11/1210:45 amMDE - DCA

1 stop11h 24mUnited Airlines

Deal found 10/14

$310

Fri 11/78:59 amDCA - BOG

1 stop10h 31mDelta

Thu 11/139:00 amBOG - DCA

1 stop8h 26mDelta

Deal found 10/15

$353

Sat 11/87:50 pmDCA - CTG

2 stops17h 36mAmerican Airlines

Tue 11/114:30 pmCTG - DCA

2 stops16h 44mAmerican Airlines

Deal found 10/14

$316

Sat 11/812:50 pmDCA - MDE

1 stop9h 15mUnited Airlines

Mon 12/151:15 amMDE - DCA

1 stop10h 17mUnited Airlines

Deal found 10/14

$334

Tue 11/116:00 amDCA - CTG

1 stop8h 14mLATAM Airlines

Sat 11/153:29 pmCTG - DCA

1 stop8h 12mLATAM Airlines

Deal found 10/15

$356

Wed 11/1212:25 pmDCA - MDE

2 stops11h 14mAmerican Airlines

Sat 11/157:00 amMDE - DCA

1 stop17h 24mAmerican Airlines

Deal found 10/15

$308

Fri 11/148:15 amDCA - MDE

1 stop13h 50mUnited Airlines

Mon 11/1710:45 amMDE - DCA

1 stop31h 57mUnited Airlines

Deal found 10/14

$342

Mon 11/1710:10 pmDCA - CTG

2 stops15h 16mAmerican Airlines

Thu 11/204:30 pmCTG - DCA

2 stops16h 44mAmerican Airlines

Deal found 10/16

$301

Sat 11/296:00 amDCA - MDE

1 stop16h 05mUnited Airlines

Fri 12/51:15 amMDE - DCA

1 stop17h 45mUnited Airlines

Deal found 10/15

$330

One-way flights from Reagan-National to South America
Search for one-way flight options from Reagan-National to South America. Find affordable one-way fares based on user searches. Data last updated October 16, 2025.

Tue 11/118:25 amDCA - CTG

1 stop7h 05mAmerican Airlines

Deal found 10/15

$123

Mon 1/52:45 pmDCA - MDE

1 stop14h 57mUnited Airlines

Deal found 10/15

$123

Wed 12/3110:15 amDCA - MDE

2 stops10h 55mAmerican Airlines

Deal found 10/16

$128

Sun 1/115:00 amDCA - MDE

1 stop18h 10mAmerican Airlines

Deal found 10/15

$129

Wed 1/217:10 amDCA - CTG

1 stop7h 40mJetBlue

Deal found 10/16

$130

Mon 1/56:00 amDCA - MDE

1 stop17h 39mAmerican Airlines

Deal found 10/16

$131

Sat 10/258:30 pmDCA - CTG

1 stop16h 55mAmerican Airlines

Deal found 10/15

$138

Fri 11/284:34 pmDCA - MDE

1 stop29h 31mUnited Airlines

Deal found 10/13

$141

Sat 11/1512:30 pmDCA - MDE

2 stops11h 09mAmerican Airlines

Deal found 10/15

$143

Tue 10/286:59 amDCA - BOG

1 stop12h 41mDelta

Deal found 10/15

$149

Sat 10/256:59 amDCA - CTG

1 stop7h 15mDelta

Deal found 10/16

$153

Fri 10/246:00 amDCA - BOG

1 stop14h 15mDelta

Deal found 10/16

$153

Cheap flight deals from Reagan-National to South America

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$301 (American Airlines)
One-way from	$123 (American Airlines)
Popular in	December
Cheapest in	October
Average price	$663

Provider with most accurate pricing for Washington, D.C. (WAS)-Sao Paulo (SAO) flight deals.

Search Deals

Provider most trusted by Cheapflights users for Washington, D.C. (WAS)-Sao Paulo (SAO) flights.

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From Washington, D.C. Reagan-National to South America

Search Deals

One-way flight from Washington, D.C. Reagan-National to South America

Search Deals

Highest demand for flights based on searches. 13% potential increase in price ($127 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($27 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in October 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Washington, D.C. Reagan-National Airport to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Washington, D.C.Medellín

DCA - MDE

DCAMDE

Washington, D.C. Reagan-National

Fri 11/7

8:15 am-10:05 pm

1 stop13h 50m

Medellín Jose Maria Cordova Intl

Wed 11/12

10:45 am-8:45 pm

1 stop10h 00m

$303

Washington, D.C.Medellín

DCA - MDE

DCAMDE

Washington, D.C. Reagan-National

Wed 10/29

12:50 pm-9:05 pm

1 stop9h 15m

Medellín Jose Maria Cordova Intl

Sat 11/1

9:45 am-8:45 pm

1 stop10h 00m

$303

Washington, D.C.Medellín

DCA - MDE

DCAMDE

Washington, D.C. Reagan-National

Wed 10/29

8:15 am-9:05 pm

1 stop13h 50m

Medellín Jose Maria Cordova Intl

Wed 11/5

10:45 am-8:45 pm

1 stop10h 00m

$303

Washington, D.C.Medellín

DCA - MDE

DCAMDE

Washington, D.C. Reagan-National

Wed 11/12

12:25 pm-11:39 pm

2 stops11h 14m

Medellín Jose Maria Cordova Intl

Sat 11/15

7:00 am-12:24 am

1 stop17h 24m

$308

Washington, D.C.Medellín

DCA - MDE

DCAMDE

Washington, D.C. Reagan-National

Thu 11/6

7:59 pm-10:05 pm

1 stop26h 06m

Medellín Jose Maria Cordova Intl

Wed 11/12

10:45 am-8:45 pm

1 stop10h 00m

$310

Washington, D.C.Medellín

DCA - MDE

DCAMDE

Washington, D.C. Reagan-National

Sat 11/29

6:00 am-10:05 pm

1 stop16h 05m

Medellín Jose Maria Cordova Intl

Sat 12/6

10:45 am-8:56 pm

1 stop10h 11m

$330

Washington, D.C.Medellín

DCA - MDE

DCAMDE

Washington, D.C. Reagan-National

Sat 11/8

12:50 pm-10:05 pm

1 stop9h 15m

Medellín Jose Maria Cordova Intl

Tue 12/16

10:45 am-10:04 pm

1 stop11h 19m

$334

Washington, D.C.Bogotá

DCA - BOG

DCABOG

Washington, D.C. Reagan-National

Wed 10/29

7:59 am-7:30 pm

1 stop12h 31m

Bogotá El Dorado

Wed 11/12

9:00 am-9:49 pm

1 stop12h 49m

$353

Washington, D.C.Bogotá

DCA - BOG

DCABOG

Washington, D.C. Reagan-National

Sun 10/26

7:00 am-7:30 pm

1 stop13h 30m

Bogotá El Dorado

Thu 10/30

6:35 pm-11:31 am

2 stops15h 56m

$353

Washington, D.C.Bogotá

DCA - BOG

DCABOG

Washington, D.C. Reagan-National

Wed 11/5

6:00 am-2:25 pm

1 stop8h 25m

Bogotá El Dorado

Wed 11/12

9:00 am-5:26 pm

1 stop8h 26m

$353

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

Showing 1-10 of 60 results

...

Best time to book a flight from Reagan-National to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Reagan-National with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Washington, D.C. Reagan-National Airport to South America

What is the cheapest month to book a flight from Washington, D.C. Reagan-National Airport to South America?

Currently, July is the cheapest month in which you can book a flight from Washington, D.C. Reagan-National Airport to South America (average of $179). Flying from Washington, D.C. Reagan-National Airport to South America in April is currently the most expensive (average of $338). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DCA to SA?

Unlike in the morning, when flights are generally more expensive, you can save up to 14% on flights from Washington, D.C. Reagan-National Airport to South America by exploring options for tickets in the evening.

What is the cheapest day to fly from Washington, D.C. Reagan-National Airport to South America?

Travelers seeking maximum savings on their Washington, D.C. Reagan-National Airport to South America flight should consider departing on Tuesday mornings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

See what other customers who have flown with Delta, Copa Airlines, and LATAM Airlines from Washington, D.C. Reagan-National Airport to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,984 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Delta

8.0

Very good

7,984 reviews

Delta

8.0

Very good

7,984 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

Copa Airlines

7.6

Good

1,551 reviews

Delta

8.0

Very good

7,984 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

LATAM Airlines

7.5

Good

1,866 reviews

Delta

8.0

Very good

7,984 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

United Airlines

7.4

Good

8,982 reviews

Delta

8.0

Very good

7,984 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

American Airlines

7.2

Good

11,043 reviews

Delta

8.0

Very good

7,984 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

Related info for your journey

How long is the flight from Washington, D.C. Reagan-National Airport to South America?
For as low as $308, United Airlines can have you in South America from Washington, D.C. Reagan-National Airport in 11h 14m. The distance between Washington, D.C. Reagan-National Airport and South America is about 2259 mi. This flight may include one or multiple stops.
What are the cheapest airlines to fly from Washington, D.C. Reagan-National Airport to South America one-way?
$123 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on American Airlines and JetBlue, with prices starting from $128 and $130, respectively.
What are the most popular routes from Washington, D.C. Reagan-National Airport to South America?
The most popular route from Washington, D.C. Reagan-National Airport to South America is Washington, D.C. Reagan-National - Lima J Chavez Intl. You may also consider Washington, D.C. Reagan-National - Bogotá El Dorado or Washington, D.C. Reagan-National - Buenos Aires Ministro Pistarini.
Can I find deals for flights from Reagan-National to South America that include hotel bookings?
Yes. In addition to deals on Reagan-National to South America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Reagan-National to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Reagan-National to South America.
Can I find deals for business class flights from Reagan-National to South America?
Yes. Cheapflights offers flight deals from Reagan-National to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Washington, D.C. Reagan-National Airport to South America?
Currently, July is the cheapest month in which you can book a flight from Washington, D.C. Reagan-National Airport to South America (average of $179). Flying from Washington, D.C. Reagan-National Airport to South America in April is currently the most expensive (average of $338). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 7 airlines flying from Reagan-National to South America

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$266	Average$705	FlexibilityNo cancel fee	On-timeN/A
LATAM Airlines	Cheapest$288	Average$649	FlexibilityNo cancel fee	On-time81%
Copa Airlines	Cheapest$290	Average$502	FlexibilityNo cancel fee	On-time70%
American Airlines	Cheapest$302	Average$765	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$302	Average$673	FlexibilityNo cancel fee	On-time69%
Avianca	Cheapest$382	Average$585	FlexibilityNo cancel fee	On-time71%
Air Canada	Cheapest$588	Average$741	FlexibilityNo cancel fee	On-time67%

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$123+ Cheap flights from Reagan-National (DCA) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.

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Find flight deals from Reagan-National to South America

Cheapest flights from Reagan-National to South AmericaExplore the most affordable flight options available from Reagan-National to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

Explore the most affordable flight options available from Reagan-National to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

Cheap flight deals from Reagan-National to South America

Keep the following information in mind while searching for Reagan-National to South America flight deals. Data was last updated October 16, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Washington, D.C. Reagan-National Airport to South America that are best for you.

Best time to book a flight from Reagan-National to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Reagan-National with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Washington, D.C. Reagan-National Airport to South America

What is the cheapest month to book a flight from Washington, D.C. Reagan-National Airport to South America?

What is the cheapest time of day to fly from DCA to SA?

Find hourly flight availability from Reagan-National to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

What is the cheapest day to fly from Washington, D.C. Reagan-National Airport to South America?

Use this chart to determine the cheapest time to fly round-trip from Reagan-National to South America. Price data was last updated on December 16, 2024.

Reviews of airlines servicing South America

See what other customers who have flown with Delta, Copa Airlines, and LATAM Airlines from Washington, D.C. Reagan-National Airport to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Reagan-National to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Washington, D.C. Reagan-National Airport to South America?

What are the cheapest airlines to fly from Washington, D.C. Reagan-National Airport to South America one-way?

What are the most popular routes from Washington, D.C. Reagan-National Airport to South America?

Can I find deals for flights from Reagan-National to South America that include hotel bookings?

How can I find direct flights from Reagan-National to South America?

Can I find deals for business class flights from Reagan-National to South America?

What is the cheapest month to book a flight from Washington, D.C. Reagan-National Airport to South America?

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Alternative routes for Reagan-National to South America

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Top 7 airlines flying from Reagan-National to South America

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Cheapest flights from Reagan-National to South America
Explore the most affordable flight options available from Reagan-National to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.