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$328+ Cheap flights from Panama City, FL (ECP) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — BOG
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Panama City to South America

Keep the following information in mind while searching for Panama City to South America flight deals. Data was last updated June 12, 2025.

Round-trip from

$503
(Delta)

One-way from

$328
(Delta)
From Panama City NW Florida Beaches to South America
Search Deals
One-way flight from Panama City NW Florida Beaches to South America
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Find flight deals from Panama City to South America

Cheapest flights from Panama City to South America
Explore the most affordable flight options available from Panama City to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/811:10 amECP - BOG
1 stop17h 44mUnited Airlines
Tue 3/31:30 amBOG - ECP
1 stop11h 22mUnited Airlines
Deal found 6/9$503
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/79:23 amECP - BOG
2 stops10h 31mDelta
Thu 3/57:00 amBOG - ECP
2 stops13h 38mDelta
Deal found 6/9$507
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/611:34 amECP - BOG
1 stop10h 27mAmerican Airlines
Thu 3/512:45 amBOG - ECP
1 stop14h 17mAmerican Airlines
Deal found 6/10$535
This United deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/285:06 pmECP - BGA
2 stops26h 19mMultiple Airlines
Wed 9/36:55 amBGA - ECP
2 stops26h 59mMultiple Airlines
Deal found 6/10$537
This United deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/136:30 amECP - BOG
2 stops11h 44mMultiple Airlines
Sun 6/158:30 amBOG - ECP
2 stops28h 36mMultiple Airlines
Deal found 6/10$811
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/138:55 amECP - BGA
2 stops34h 39mUnited Airlines
Fri 6/206:56 pmBGA - ECP
2 stops24h 15mUnited Airlines
Deal found 6/11$1,015
This United deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/811:10 amECP - CUZ
2 stops23h 50mMultiple Airlines
Fri 7/1112:15 pmCUZ - ECP
2 stops21h 41mMultiple Airlines
Deal found 6/11$1,190
This United deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/175:07 pmECP - LPB
2 stops32h 03mMultiple Airlines
Thu 6/193:25 pmLPB - ECP
3 stops28h 46mMultiple Airlines
Deal found 6/10$1,292
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/811:46 amECP - CUZ
3 stops19h 38mAmerican Airlines
Fri 7/115:17 pmCUZ - ECP
3 stops20h 48mAmerican Airlines
Deal found 6/11$2,884

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Panama City to South America that are best for you.

Fly from

Panama City

Fly to

South America

Route

Depart

Return

Price

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Wed 10/8

7:45 am-7:15 pm

1 stop11h 30m

Bogotá El Dorado

Wed 3/4

3:55 pm-8:20 am

1 stop17h 25m

$503

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Tue 10/7

6:30 am-7:20 pm

1 stop12h 50m

Bogotá El Dorado

Wed 3/4

1:30 am-7:52 pm

1 stop19h 22m

$516

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Mon 10/6

11:34 am-10:01 pm

1 stop10h 27m

Bogotá El Dorado

Thu 3/5

12:45 am-2:02 pm

1 stop14h 17m

$535

Panama CityBucaramanga

ECP - BGA

ECPBGA

Panama City NW Florida Beaches

Thu 8/28

5:06 pm-7:25 pm

2 stops26h 19m

Bucaramanga Palo Negro

Wed 9/3

6:55 am-9:54 am

2 stops26h 59m

$537

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Mon 6/30

5:02 pm-1:20 pm

2 stops20h 18m

Bogotá El Dorado

Fri 7/4

12:14 am-1:23 pm

2 stops37h 09m

$897

Panama CityCusco

ECP - CUZ

ECPCUZ

Panama City NW Florida Beaches

Tue 7/8

11:10 am-11:00 am

2 stops23h 50m

Cusco Velazco Astete

Fri 7/11

12:15 pm-9:56 am

2 stops21h 41m

$1,190

Panama CityCusco

ECP - CUZ

ECPCUZ

Panama City NW Florida Beaches

Tue 7/8

11:46 am-7:24 am

3 stops19h 38m

Cusco Velazco Astete

Fri 7/11

5:17 pm-2:05 pm

3 stops20h 48m

$2,884

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Wed 8/20

1:53 pm-12:00 pm

2 stops22h 07m

$328

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Mon 7/7

6:55 pm-1:05 pm

2 stops18h 10m

$338

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

Tue 6/17

8:55 am-7:20 pm

1 stop10h 25m

$341

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 11 results
1
2

Best time to book a flight from Panama City to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to South America

What is the cheapest month to book a flight from Panama City, Florida to South America?

Currently, May is the cheapest month in which you can book a flight from Panama City, Florida to South America (average of $359). Flying from Panama City, Florida to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to SA?

Find hourly flight availability from Panama City to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated June 12, 2025.
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to South America?

    Located just 16.0 mi from the city center, Panama City NW Florida Beaches (ECP) is the airport most travelers will use when flying to South America from Panama City.

  • What are the cheapest airlines to fly from Panama City, Florida to South America one-way?

    $328 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $338 and $356, respectively.

  • What are the most popular routes from Panama City, Florida to South America?

    The most popular flight routes from Panama City, Florida to South America are Panama City NW Florida Beaches - Bogotá El Dorado, Panama City NW Florida Beaches - Guayaquil Jose Joaquin de Olmedo and Panama City NW Florida Beaches - Belém Val De Cans.

  • Can I find deals for flights from Panama City to South America that include hotel bookings?

    Yes. In addition to deals on Panama City to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to South America.

  • Can I find deals for business class flights from Panama City to South America?

    Yes. Cheapflights offers flight deals from Panama City to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to South America?

    Currently, May is the cheapest month in which you can book a flight from Panama City, Florida to South America (average of $359). Flying from Panama City, Florida to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Panama City to South America

Discover the top 2 airlines that operate flights from Panama City to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$448Average$704FlexibilityNo cancel feeOn-time69%
DeltaCheapest$479Average$636FlexibilityNo cancel feeOn-timeN/A

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