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South America

$259+ Cheap flights from Panama City, FL (ECP) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — BOG
feb. 26 — mar. 51
jue. 2/26
jue. 3/5
1 adult, Economy
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Cheap flight deals from Panama City to South America

Cheapest flights from Panama City to South America
Explore the most affordable flight options available from Panama City to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 27, 2026.

This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/52:10 pm
ECP
-
BOG
1 stop14h 20m
Multiple Airlines
mié. 3/119:10 am
BOG
-
ECP
2 stops12h 47m
Multiple Airlines
Deal found 1/27$521
This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/136:30 am
ECP
-
BOG
2 stops18h 20m
Multiple Airlines
dom. 2/154:00 am
BOG
-
ECP
2 stops13h 11m
Multiple Airlines
Deal found 1/27$522
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/167:05 am
ECP
-
BOG
1 stop12h 25m
Delta
mié. 3/253:55 pm
BOG
-
ECP
1 stop16h 45m
Delta
Deal found 1/26$537
This LATAM Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/169:25 am
ECP
-
BOG
2 stops10h 55m
Multiple Airlines
mié. 3/257:00 am
BOG
-
ECP
2 stops16h 04m
Multiple Airlines
Deal found 1/26$542
This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/111:10 pm
ECP
-
BOG
2 stops11h 40m
Multiple Airlines
sáb. 2/144:00 am
BOG
-
ECP
2 stops13h 11m
Multiple Airlines
Deal found 1/27$550
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/96:00 am
ECP
-
BOG
1 stop13h 25m
Delta
vie. 5/229:00 am
BOG
-
ECP
1 stop10h 36m
Delta
Deal found 1/26$557
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/162:10 pm
ECP
-
BOG
2 stops15h 00m
United Airlines
mar. 3/241:30 am
BOG
-
ECP
1 stop10h 34m
United Airlines
Deal found 1/26$559
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/96:44 am
ECP
-
BOG
1 stop15h 46m
American Airlines
vie. 5/2212:25 pm
BOG
-
ECP
2 stops22h 00m
American Airlines
Deal found 1/27$562
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/307:01 am
ECP
-
BOG
1 stop15h 04m
American Airlines
dom. 10/42:35 pm
BOG
-
ECP
2 stops19h 35m
American Airlines
Deal found 1/27$576
This KAYAK deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/56:30 am
ECP
-
BOG
1 stop15h 05m
Azul
mié. 3/118:15 am
BOG
-
ECP
1 stop13h 42m
Azul
Deal found 1/27$582
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/57:19 am
ECP
-
BOG
2 stops13h 51m
American Airlines
mié. 3/112:15 pm
BOG
-
ECP
2 stops22h 29m
American Airlines
Deal found 1/27$588
This Ovago deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/92:15 pm
ECP
-
BOG
2 stops14h 39m
Multiple Airlines
mar. 6/1612:14 am
BOG
-
ECP
1 stop10h 51m
Multiple Airlines
Deal found 1/25$593

Find flight deals from Panama City to South America

Keep the following information in mind while searching for Panama City to South America flight deals. Data was last updated enero 27, 2026.

Round-trip from

$522
(Avianca)

One-way from

$259
(Avianca)
From Panama City NW Florida Beaches to South America
Search Deals
One-way flight from Panama City NW Florida Beaches to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 27, 2026.
Use the filters below to find and compare flights from Panama City to South America that are best for you.

Fly from

Panama City

Fly to

South America

Route

Depart

Return

Price

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

jue. 3/5

2:10 pm-5:30 am

1 stop14h 20m

Bogotá El Dorado

mié. 3/11

9:10 am-9:57 pm

2 stops12h 47m

$521

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

mar. 6/9

3:10 pm-4:54 am

1 stop13h 44m

Bogotá El Dorado

mié. 6/17

8:30 am-7:06 pm

1 stop10h 36m

$537

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

lun. 3/16

7:05 am-7:30 pm

1 stop12h 25m

Bogotá El Dorado

mié. 3/25

3:55 pm-8:40 am

1 stop16h 45m

$537

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

mié. 2/11

1:10 pm-1:50 am

2 stops11h 40m

Bogotá El Dorado

sáb. 2/14

4:00 am-4:11 pm

2 stops13h 11m

$550

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

sáb. 5/9

7:45 am-7:25 pm

1 stop11h 40m

Bogotá El Dorado

vie. 5/22

9:00 am-7:36 pm

1 stop10h 36m

$557

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

lun. 3/16

2:10 pm-5:10 am

2 stops15h 00m

Bogotá El Dorado

mar. 3/24

1:30 am-12:04 pm

1 stop10h 34m

$559

Panama CityBogotá

ECP - BOG

ECPBOG

Panama City NW Florida Beaches

sáb. 5/9

6:44 am-10:30 pm

1 stop15h 46m

Bogotá El Dorado

vie. 5/22

2:10 pm-10:25 am

2 stops20h 15m

$562

Panama CityBucaramanga

ECP - BGA

ECPBGA

Panama City NW Florida Beaches

mar. 2/24

6:30 am-7:39 pm

2 stops12h 09m

Bucaramanga Palo Negro

jue. 2/26

7:00 am-12:04 pm

2 stops30h 04m

$627

Panama CityGuayaquil

ECP - GYE

ECPGYE

Panama City NW Florida Beaches

mar. 3/10

6:30 am-5:33 pm

2 stops35h 03m

Guayaquil Jose Joaquin de Olmedo

vie. 3/20

8:32 am-12:04 pm

2 stops27h 32m

$645

Panama CityLa Paz

ECP - LPB

ECPLPB

Panama City NW Florida Beaches

vie. 5/22

11:35 am-2:20 am

2 stops13h 45m

La Paz El Alto Intl

mié. 5/27

3:25 am-8:00 pm

2 stops17h 35m

$745

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 20 results
1
2

Best time to book a flight from Panama City to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to South America

What is the cheapest month to book a flight from Panama City, Florida to South America?

Currently, February is the cheapest month in which you can book a flight from Panama City, Florida to South America (average of $256). Flying from Panama City, Florida to South America in June is currently the most expensive (average of $531). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated enero 27, 2026.
Read reviews from past customers who have flown Delta and United Airlines from Panama City to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,119 reviews

Crew

8.5

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,119 reviews
Delta
7.9
Good
8,119 reviews

Crew

8.5

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
9,205 reviews
Delta
7.9
Good
8,119 reviews

Crew

8.5

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to South America?

    Located just 16.0 mi from the city center, Panama City NW Florida Beaches (ECP) is the airport most travelers will use when flying to South America from Panama City.

  • How long is the flight from Panama City, Florida to South America?

    A quick flight from Panama City, Florida to South America can take about 12h 25m. United Airlines provides one of the quickest options available for as low as $537. Airlines will cover a distance of 1927 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Panama City, Florida to South America?

    The most popular flight routes from Panama City, Florida to South America are Panama City NW Florida Beaches - Bogotá El Dorado, Panama City NW Florida Beaches - Guayaquil Jose Joaquin de Olmedo and Panama City NW Florida Beaches - Bucaramanga Palo Negro.

  • Can I find deals for flights from Panama City to South America that include hotel bookings?

    Yes. In addition to deals on Panama City to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to South America.

  • Can I find deals for business class flights from Panama City to South America?

    Yes. Cheapflights offers flight deals from Panama City to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to South America?

    Currently, February is the cheapest month in which you can book a flight from Panama City, Florida to South America (average of $256). Flying from Panama City, Florida to South America in June is currently the most expensive (average of $531). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Panama City to South America

Discover the top airline that operate flights from Panama City to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$482Average$773FlexibilityNo cancel feeOn-timeN/A

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