South America

$626+ Cheap flights from Medford (MFR) to South America

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/22. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — BOG
Feb 28 — Mar 71
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Medford to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Medford to South America

Cheapest flights from Medford to South America
Explore the most affordable flight options available from Medford to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/225:02 am
MFR
-
BOG
2 stops21h 08m
United Airlines
Tue 2/248:15 am
BOG
-
MFR
2 stops29h 41m
United Airlines
Deal found 1/28$626
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/175:00 am
MFR
-
UIO
2 stops16h 30m
United Airlines
Wed 3/1812:35 am
UIO
-
MFR
2 stops24h 23m
United Airlines
Deal found 1/28$730
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:34 pm
MFR
-
UIO
2 stops26h 51m
United Airlines
Fri 6/197:25 am
UIO
-
MFR
2 stops31h 44m
United Airlines
Deal found 1/27$765
This KAYAK deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:00 am
MFR
-
UIO
2 stops40h 30m
Multiple Airlines
Tue 3/1712:35 am
UIO
-
MFR
2 stops24h 23m
Multiple Airlines
Deal found 1/27$829
This LATAM Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:00 am
MFR
-
SCL
2 stops20h 25m
Multiple Airlines
Mon 8/106:45 pm
SCL
-
MFR
2 stops23h 28m
Multiple Airlines
Deal found 1/27$875
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:30 pm
MFR
-
SCL
2 stops34h 45m
Delta
Fri 5/110:30 am
SCL
-
MFR
2 stops28h 17m
Delta
Deal found 1/28$936
This Ovago deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:11 pm
MFR
-
SCL
2 stops18h 34m
Multiple Airlines
Fri 4/2411:25 pm
SCL
-
MFR
1 stop18h 32m
Multiple Airlines
Deal found 1/28$965
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:00 am
MFR
-
SCL
2 stops22h 50m
Delta
Fri 4/2411:25 pm
SCL
-
MFR
2 stops26h 14m
Delta
Deal found 1/27$976
This Ovago deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/127:15 am
MFR
-
SCL
1 stop19h 20m
Multiple Airlines
Fri 5/111:25 pm
SCL
-
MFR
1 stop27h 34m
Multiple Airlines
Deal found 1/28$1,022
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/121:10 pm
MFR
-
UIO
2 stops37h 50m
United Airlines
Sun 6/287:25 am
UIO
-
MFR
2 stops39h 45m
United Airlines
Deal found 1/28$1,027
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/165:00 am
MFR
-
UIO
2 stops16h 30m
United Airlines
Tue 3/1712:35 am
UIO
-
MFR
2 stops24h 23m
United Airlines
Deal found 1/26$1,097
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:00 am
MFR
-
UIO
2 stops16h 30m
United Airlines
Fri 3/2712:35 am
UIO
-
MFR
2 stops48h 39m
United Airlines
Deal found 1/27$1,150

Find flight deals from Medford to South America

Keep the following information in mind while searching for Medford to South America flight deals. Data was last updated January 29, 2026.

Round-trip from

$626
(United Airlines)
From Medford to South America

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Medford to South America that are best for you.

Fly from

Medford

Fly to

South America

Route

Depart

Return

Price

MedfordBogotá

MFR - BOG

MFRBOG

Medford

Sun 2/22

5:02 am-5:10 am

2 stops21h 08m

Bogotá El Dorado

Tue 2/24

8:15 am-10:56 am

2 stops29h 41m

$626

MedfordQuito

MFR - UIO

MFRUIO

Medford

Tue 3/17

5:00 am-11:30 pm

2 stops16h 30m

Quito Mariscal Sucr

Wed 3/18

12:35 am-10:58 pm

2 stops24h 23m

$730

MedfordQuito

MFR - UIO

MFRUIO

Medford

Sun 6/7

6:34 pm-11:25 pm

2 stops26h 51m

Quito Mariscal Sucr

Fri 6/19

7:25 am-1:09 pm

2 stops31h 44m

$765

MedfordQuito

MFR - UIO

MFRUIO

Medford

Thu 3/12

5:00 am-11:30 pm

2 stops40h 30m

Quito Mariscal Sucr

Tue 3/17

12:35 am-10:58 pm

2 stops24h 23m

$829

MedfordSantiago

MFR - SCL

MFRSCL

Medford

Sun 4/12

5:30 pm-7:15 am

2 stops34h 45m

Santiago Arturo Merino Benitez

Fri 5/1

10:30 am-11:47 am

2 stops28h 17m

$936

MedfordSantiago

MFR - SCL

MFRSCL

Medford

Fri 4/10

4:11 pm-1:45 pm

2 stops18h 34m

Santiago Arturo Merino Benitez

Fri 4/24

11:25 pm-2:57 pm

1 stop18h 32m

$965

MedfordSantiago

MFR - SCL

MFRSCL

Medford

Sun 4/12

7:15 am-5:35 am

1 stop19h 20m

Santiago Arturo Merino Benitez

Fri 5/1

9:10 pm-11:59 pm

2 stops29h 49m

$971

MedfordSantiago

MFR - SCL

MFRSCL

Medford

Fri 4/10

5:00 am-6:50 am

2 stops22h 50m

Santiago Arturo Merino Benitez

Fri 4/24

11:25 pm-10:39 pm

2 stops26h 14m

$976

MedfordQuito

MFR - UIO

MFRUIO

Medford

Fri 6/12

1:10 pm-5:00 am

2 stops37h 50m

Quito Mariscal Sucr

Sun 6/28

7:25 am-9:10 pm

2 stops39h 45m

$1,027

MedfordQuito

MFR - UIO

MFRUIO

Medford

Mon 3/16

5:00 am-11:30 pm

2 stops16h 30m

Quito Mariscal Sucr

Tue 3/17

12:35 am-10:58 pm

2 stops24h 23m

$1,097

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 11 results
1
2

Best time to book a flight from Medford to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to South America
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated January 29, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Medford to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Food

6.6

Crew

8.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Food

6.6

Crew

8.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Food

6.6

Crew

8.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Medford to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Medford to South America?

    Medford (MFR) is the airport you will fly out of if you book a flight from Medford to South America. It is only a 3.0 mi journey to Medford (MFR) from Medford’s city center.

  • How long is the flight from Medford to South America?

    There are many flights that can get you from Medford to South America in 21h 08m. Fly via United Airlines or Delta to get the fastest option. There are 3953 mi between Medford and South America. This flight may include one or multiple stops.

  • What are the most popular routes from Medford to South America?

  • Can I find deals for flights from Medford to South America that include hotel bookings?

    Yes. In addition to deals on Medford to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to South America.

  • Can I find deals for business class flights from Medford to South America?

    Yes. Cheapflights offers flight deals from Medford to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Medford to South America

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.