South America

$409+ Cheap flights from Medford (MFR) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — BOG
Oct 16 — Oct 231
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Cheap flight deals from Medford to South America

Keep the following information in mind while searching for Medford to South America flight deals. Data was last updated September 16, 2025.

Round-trip from

$818
(United Airlines)

One-way from

$409
(Copa Airlines)
From Medford to South America
One-way flight from Medford to South America

Find flight deals from Medford to South America

Cheapest flights from Medford to South America
Explore the most affordable flight options available from Medford to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/35:15 amMFR - SCL
2 stops19h 45mDelta
Thu 11/1311:40 pmSCL - MFR
2 stops29h 16mDelta
Deal found 9/16$818
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/95:20 amMFR - UIO
2 stops14h 44mAmerican Airlines
Mon 11/1012:55 amUIO - MFR
2 stops16h 04mAmerican Airlines
Deal found 9/13$829
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/95:00 amMFR - UIO
2 stops16h 30mUnited Airlines
Mon 11/101:35 amUIO - MFR
3 stops23h 55mUnited Airlines
Deal found 9/13$924

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Medford to South America that are best for you.

Fly from

Medford

Fly to

South America

Route

Depart

Return

Price

MedfordSantiago

MFR - SCL

MFRSCL

Medford

Mon 11/3

6:00 am-8:50 am

2 stops21h 50m

Santiago Arturo Merino Benitez

Thu 11/13

10:45 pm-10:30 pm

3 stops28h 45m

$818

MedfordSantiago

MFR - SCL

MFRSCL

Medford

Mon 11/3

5:15 am-6:00 am

2 stops19h 45m

Santiago Arturo Merino Benitez

Thu 11/13

11:40 pm-11:30 pm

2 stops28h 50m

$818

MedfordSantiago

MFR - SCL

MFRSCL

Medford

Thu 12/4

12:41 pm-9:55 pm

2 stops28h 14m

Santiago Arturo Merino Benitez

Mon 12/8

11:10 pm-4:43 pm

2 stops22h 33m

$818

MedfordQuito

MFR - UIO

MFRUIO

Medford

Sun 11/9

5:20 am-11:04 pm

2 stops14h 44m

Quito Mariscal Sucr

Mon 11/10

12:55 am-1:59 pm

2 stops16h 04m

$829

MedfordQuito

MFR - UIO

MFRUIO

Medford

Sun 11/9

5:00 am-12:30 am

2 stops16h 30m

Quito Mariscal Sucr

Mon 11/10

1:35 am-10:30 pm

3 stops23h 55m

$924

MedfordSantiago

MFR - SCL

MFRSCL

Medford

Tue 9/30

6:37 pm-12:04 am

2 stops25h 27m

$409

MedfordSantiago

MFR - SCL

MFRSCL

Medford

Sat 9/27

6:15 am-6:59 am

2 stops20h 44m

$658

MedfordSantiago

MFR - SCL

MFRSCL

Medford

Sat 9/27

5:58 am-6:00 am

1 stop20h 02m

$714

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Best time to book a flight from Medford to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to South America
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 16, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Medford to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Medford to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Medford to South America?

    Medford (MFR) is the airport you will fly out of if you book a flight from Medford to South America. It is only a 3.0 mi journey to Medford (MFR) from Medford’s city center.

  • How long is the flight from Medford to South America?

    There are many flights that can get you from Medford to South America in 14h 44m. Fly via United Airlines, Delta, or American Airlines to get the fastest option. There are 4026 mi between Medford and South America. This flight may include one or multiple stops.

  • What are the most popular routes from Medford to South America?

  • Can I find deals for flights from Medford to South America that include hotel bookings?

    Yes. In addition to deals on Medford to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to South America.

  • Can I find deals for business class flights from Medford to South America?

    Yes. Cheapflights offers flight deals from Medford to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to South America?

    Currently, May is the cheapest month in which you can book a flight from Medford to South America (average of $359). Flying from Medford to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Medford to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Medford to South America

Discover the top airline that operate flights from Medford to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$669Average$813FlexibilityNo cancel feeOn-timeN/A

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