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South America

$106+ Cheap flights from Durham, NC to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — BOG
nov. 29 — dic. 61
sáb. 11/29
sáb. 12/6
1 adult, Economy
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Cheap flight deals from Durham to South America

Keep the following information in mind while searching for Durham to South America flight deals. Data was last updated octubre 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$253
(Copa Airlines)

One-way from

$106
(Copa Airlines)

Popular in

January

Cheapest in

November

Average price

$614
Provider with most accurate pricing for Raleigh-Durham-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Raleigh-Durham-Sao Paulo (SAO) flights.
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From Durham to South America
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One-way flight from Durham to South America
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Highest demand for flights based on searches. 15% potential increase in price ($118 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Durham to South America

Cheapest flights from Durham to South America
Explore the most affordable flight options available from Durham to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 30, 2025.

This Copa Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/263:14 pmRDU - MDE
1 stop17h 04mCopa Airlines
mié. 12/105:00 amMDE - RDU
1 stop8h 25mCopa Airlines
Deal found 10/30$253
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/203:14 pmRDU - MDE
1 stop17h 04mCopa Airlines
dom. 11/2312:42 pmMDE - RDU
1 stop24h 45mCopa Airlines
Deal found 10/30$267
This Copa Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/103:14 pmRDU - MDE
1 stop17h 35mCopa Airlines
lun. 12/85:00 amMDE - RDU
1 stop8h 25mCopa Airlines
Deal found 10/30$285
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/53:11 pmRDU - MDE
1 stop17h 07mCopa Airlines
mié. 12/105:00 amMDE - RDU
1 stop8h 25mCopa Airlines
Deal found 10/28$287
This SmartFares deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/73:14 pmRDU - MDE
1 stop17h 04mCopa Airlines
sáb. 11/159:44 amMDE - RDU
1 stop27h 43mCopa Airlines
Deal found 10/28$302
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/106:07 amRDU - MDE
1 stop15h 58mUnited Airlines
dom. 12/71:15 amMDE - RDU
1 stop14h 25mUnited Airlines
Deal found 10/30$303
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/186:00 amRDU - MDE
2 stops16h 05mUnited Airlines
lun. 12/81:15 amMDE - RDU
2 stops12h 52mUnited Airlines
Deal found 10/28$311
This JetBlue deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/297:15 amRDU - MDE
1 stop7h 17mJetBlue
jue. 11/62:10 pmMDE - RDU
1 stop7h 56mJetBlue
Deal found 10/28$315
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/94:48 pmRDU - MDE
1 stop12h 54mUnited Airlines
dom. 12/141:15 amMDE - RDU
1 stop14h 25mUnited Airlines
Deal found 10/30$320
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/296:00 amRDU - MDE
2 stops16h 05mUnited Airlines
mié. 11/510:45 amMDE - RDU
2 stops23h 29mUnited Airlines
Deal found 10/28$323
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/106:07 amRDU - BOG
1 stop16h 28mUnited Airlines
mié. 12/241:30 amBOG - RDU
1 stop9h 51mUnited Airlines
Deal found 10/28$323
This Trip.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/1512:40 pmRDU - BOG
1 stop25h 45mDelta
vie. 11/289:00 amBOG - RDU
1 stop15h 20mDelta
Deal found 10/29$324

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
Use the filters below to find and compare flights from Durham to South America that are best for you.

Fly from

Durham

Fly to

South America

Route

Depart

Return

Price

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

mié. 11/26

3:14 pm-8:18 am

1 stop17h 04m

Medellín Jose Maria Cordova Intl

mié. 12/10

5:00 am-1:25 pm

1 stop8h 25m

$253

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

lun. 11/10

3:14 pm-8:18 am

1 stop17h 04m

Medellín Jose Maria Cordova Intl

lun. 12/8

5:00 am-1:25 pm

1 stop8h 25m

$285

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

dom. 1/11

3:09 pm-8:18 am

1 stop17h 09m

Medellín Jose Maria Cordova Intl

vie. 1/30

5:00 am-1:15 pm

1 stop8h 15m

$287

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

vie. 12/5

3:11 pm-8:18 am

1 stop17h 07m

Medellín Jose Maria Cordova Intl

mié. 12/10

5:00 am-1:25 pm

1 stop8h 25m

$287

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

lun. 1/12

3:09 pm-8:18 am

1 stop17h 09m

Medellín Jose Maria Cordova Intl

lun. 1/19

5:00 am-1:15 pm

1 stop8h 15m

$298

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

jue. 2/5

10:20 am-10:05 pm

2 stops11h 45m

Medellín Jose Maria Cordova Intl

lun. 2/9

10:45 am-10:30 pm

1 stop11h 45m

$308

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

vie. 2/6

5:18 pm-10:05 pm

2 stops28h 47m

Medellín Jose Maria Cordova Intl

mar. 2/10

10:45 am-2:06 pm

3 stops27h 21m

$308

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

lun. 11/10

10:35 am-10:05 pm

2 stops11h 30m

Medellín Jose Maria Cordova Intl

lun. 12/8

10:45 am-10:14 am

2 stops23h 29m

$308

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

mié. 2/11

6:15 am-10:35 pm

1 stop16h 20m

Bogotá El Dorado

mié. 2/18

8:15 am-9:30 am

2 stops25h 15m

$308

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

jue. 2/19

4:47 pm-5:10 am

1 stop12h 23m

Bogotá El Dorado

dom. 2/22

8:15 am-2:03 pm

3 stops29h 48m

$308

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 60 results
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Best time to book a flight from Durham to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to South America

What is the cheapest month to book a flight from Durham to South America?

Currently, March is the cheapest month in which you can book a flight from Durham to South America (average of $154). Flying from Durham to South America in July is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SA?

Find hourly flight availability from Durham to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 30, 2025.

It’s typically best to fly out from Durham to South America in the afternoon. Doing so could potentially save you 7% on the flight price compared to flying in the evening, which is usually more expensive.

What is the cheapest day to fly from Durham to South America?

Use this chart to determine the cheapest time to fly round-trip from Durham to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Durham to South America flight should consider departing on Tuesday at noon when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated octubre 30, 2025.
Peruse reviews from past customers who have flown with Delta, Copa Airlines, and LATAM Airlines from Durham to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Copa Airlines
7.6
Good
1,561 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
LATAM Airlines
7.5
Good
1,873 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,998 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,035 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Durham to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Durham to South America?

    There are many flights that can get you from Durham to South America in 16h 20m. Fly via Copa Airlines, United Airlines, or Delta to get the fastest option. Durham and South America are separated by a distance of 2173 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Durham to South America one-way?

    The cheapest airlines for a one-way flight from Durham to South America are Copa Airlines ($106), Spirit Airlines ($107), and United Airlines ($128).

  • What are the most popular routes from Durham to South America?

    While some choose either Raleigh-Durham - Bogotá El Dorado or Raleigh-Durham - Lima J Chavez Intl, Raleigh-Durham - Medellín Jose Maria Cordova Intl is the most popular route from Durham to South America.

  • Can I find deals for flights from Durham to South America that include hotel bookings?

    Yes. In addition to deals on Durham to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to South America.

  • Can I find deals for business class flights from Durham to South America?

    Yes. Cheapflights offers flight deals from Durham to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to South America?

    Currently, March is the cheapest month in which you can book a flight from Durham to South America (average of $154). Flying from Durham to South America in July is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Durham to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from Durham to South America

Discover the top 8 airlines that operate flights from Durham to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$164Average$742FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$225Average$624FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$245Average$614FlexibilityNo cancel feeOn-time70%
Spirit AirlinesCheapest$260Average$671FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$283Average$742FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$314Average$761FlexibilityNo cancel feeOn-time69%
JetBlueCheapest$374Average$475FlexibilityNo cancel feeOn-time62%
GOLCheapest$540Average$1,208FlexibilityNo cancel feeOn-time74%

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