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South America

$100+ Cheap flights from Durham, NC to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — BOG
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Durham to South America

Keep the following information in mind while searching for Durham to South America flight deals. Data was last updated September 11, 2025.

Round-trip from

$273
(American Airlines)

One-way from

$100
(SmartFares)

Popular in

January

Cheapest in

March

Average price

$571
From Durham to South America
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One-way flight from Durham to South America
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Highest demand for flights based on searches. 17% potential increase in price ($130 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($28 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Durham to South America

Cheapest flights from Durham to South America
Explore the most affordable flight options available from Durham to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/264:21 pmRDU - MDE
1 stop16h 56mCopa Airlines
Wed 10/15:04 amMDE - RDU
1 stop8h 23mCopa Airlines
Deal found 9/9$253
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/104:19 pmRDU - MDE
1 stop17h 51mCopa Airlines
Wed 10/226:37 amMDE - RDU
1 stop6h 50mCopa Airlines
Deal found 9/8$267
This Trip.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/187:15 amRDU - MDE
1 stop7h 50mJetBlue
Tue 10/211:30 pmMDE - RDU
1 stop7h 40mJetBlue
Deal found 9/9$280
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/217:15 amRDU - MDE
1 stop7h 50mJetBlue
Wed 10/291:10 pmMDE - RDU
1 stop7h 56mJetBlue
Deal found 9/10$281
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:00 amRDU - MDE
1 stop7h 35mAmerican Airlines
Mon 11/33:10 pmMDE - RDU
1 stop9h 16mAmerican Airlines
Deal found 9/10$283
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/103:14 pmRDU - BOG
1 stop8h 51mCopa Airlines
Fri 11/146:10 amBOG - RDU
1 stop7h 17mCopa Airlines
Deal found 9/11$284
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:07 amRDU - MDE
2 stops15h 08mAmerican Airlines
Wed 11/127:00 amMDE - RDU
1 stop11h 10mAmerican Airlines
Deal found 9/11$287
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/53:14 pmRDU - BOG
1 stop8h 51mCopa Airlines
Tue 11/114:45 amBOG - RDU
1 stop8h 42mCopa Airlines
Deal found 9/9$287
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/187:51 pmRDU - MDE
1 stop17h 44mAmerican Airlines
Tue 10/216:00 amMDE - RDU
1 stop15h 14mAmerican Airlines
Deal found 9/11$290
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/244:19 pmRDU - BOG
1 stop7h 36mCopa Airlines
Wed 10/296:10 amBOG - RDU
1 stop7h 17mCopa Airlines
Deal found 9/11$291
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:55 pmRDU - BOG
1 stop17h 45mAmerican Airlines
Sat 11/81:40 pmBOG - RDU
1 stop10h 46mAmerican Airlines
Deal found 9/10$296
This JetBlue deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/187:15 amRDU - MDE
1 stop7h 50mJetBlue
Wed 10/221:30 pmMDE - RDU
1 stop7h 40mJetBlue
Deal found 9/9$297

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Durham to South America that are best for you.

Fly from

Durham

Fly to

South America

Route

Depart

Return

Price

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Fri 11/7

3:14 pm-12:20 am

1 stop9h 06m

Bogotá El Dorado

Fri 11/14

6:10 am-1:27 pm

1 stop7h 17m

$284

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Mon 11/10

3:14 pm-10:55 pm

1 stop7h 41m

Bogotá El Dorado

Fri 11/14

6:10 am-1:27 pm

1 stop7h 17m

$284

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Thu 10/30

6:07 am-8:15 pm

2 stops15h 08m

Medellín Jose Maria Cordova Intl

Tue 11/11

1:30 am-1:08 pm

2 stops11h 38m

$287

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Wed 11/5

3:14 pm-12:05 am

1 stop8h 51m

Bogotá El Dorado

Tue 11/11

4:45 am-1:27 pm

1 stop8h 42m

$287

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Fri 10/24

4:19 pm-10:55 pm

1 stop7h 36m

Bogotá El Dorado

Wed 10/29

6:10 am-2:27 pm

1 stop7h 17m

$291

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Fri 10/10

4:19 pm-8:17 am

1 stop16h 58m

Medellín Jose Maria Cordova Intl

Mon 10/13

5:04 am-2:27 pm

1 stop8h 23m

$298

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Fri 11/28

1:15 pm-10:35 pm

1 stop9h 20m

Bogotá El Dorado

Fri 12/5

1:30 am-3:44 pm

1 stop14h 14m

$303

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Fri 10/17

4:19 pm-10:51 pm

1 stop7h 32m

Medellín Jose Maria Cordova Intl

Mon 10/20

6:37 am-2:27 pm

1 stop6h 50m

$306

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Wed 10/8

12:09 pm-9:17 pm

2 stops10h 08m

Bogotá El Dorado

Tue 10/21

6:30 am-8:54 pm

2 stops13h 24m

$307

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Tue 10/21

12:09 pm-9:17 pm

2 stops10h 08m

Bogotá El Dorado

Wed 10/29

6:50 am-11:06 pm

2 stops15h 16m

$307

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 60 results
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Best time to book a flight from Durham to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to South America

What is the cheapest month to book a flight from Durham to South America?

Currently, May is the cheapest month in which you can book a flight from Durham to South America (average of $359). Flying from Durham to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SA?

Find hourly flight availability from Durham to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Durham to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Delta, Copa Airlines, and LATAM Airlines from Durham to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.6
Good
1,531 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,847 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Durham to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Durham to South America?

    There are many flights that can get you from Durham to South America in 9h 06m. Fly via Copa Airlines, American Airlines, or Spirit Airlines to get the fastest option. Durham and South America are separated by a distance of 2173 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Durham to South America one-way?

    The cheapest airlines for a one-way flight from Durham to South America are JetBlue ($100), Copa Airlines ($106), and American Airlines ($118).

  • What are the most popular routes from Durham to South America?

    While some choose either Raleigh-Durham - Bogotá El Dorado or Raleigh-Durham - Lima J Chavez Intl, Raleigh-Durham - Medellín Jose Maria Cordova Intl is the most popular route from Durham to South America.

  • Can I find deals for flights from Durham to South America that include hotel bookings?

    Yes. In addition to deals on Durham to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to South America.

  • Can I find deals for business class flights from Durham to South America?

    Yes. Cheapflights offers flight deals from Durham to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to South America?

    Currently, May is the cheapest month in which you can book a flight from Durham to South America (average of $359). Flying from Durham to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from Durham to South America

Discover the top 8 airlines that operate flights from Durham to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$189Average$777FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$222Average$757FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$225Average$632FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$246Average$527FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$288Average$728FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$311Average$680FlexibilityNo cancel feeOn-time69%
JetBlueCheapest$374Average$491FlexibilityNo cancel feeOn-time62%
GOLCheapest$481Average$620FlexibilityNo cancel feeOn-time74%

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