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South America

$134+ Cheap flights from Durham, NC to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — BOG
may. 4 — may. 111
dom. 5/4
dom. 5/11
1 adult, Economy
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Cheap flight deals from Durham to South America

Keep the following information in mind while searching for Durham to South America flight deals. Data was last updated abril 29, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$289
(Delta)

One-way from

$134
(Kiwi.com)

Popular in

May

Cheapest in

March

Average price

$565
Provider with most accurate pricing for Raleigh-Durham-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Raleigh-Durham-Sao Paulo (SAO) flights.
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From Durham to South America
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One-way flight from Durham to South America
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Highest demand for flights based on searches. 16% potential increase in price ($145 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($33 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Durham to South America

Cheapest flights from Durham to South America
Explore the most affordable flight options available from Durham to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 29, 2025.

This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/227:10 amRDU - BOG
1 stop13h 40mDelta
sáb. 5/311:35 amBOG - RDU
1 stop17h 14mDelta
Deal found 4/28$289
This LATAM Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/512:34 pmRDU - BOG
1 stop8h 36mLATAM Airlines
lun. 6/97:00 amBOG - RDU
1 stop8h 17mLATAM Airlines
Deal found 4/28$290
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/46:55 amRDU - BOG
1 stop16h 00mAmerican Airlines
lun. 11/103:00 amBOG - RDU
1 stop9h 15mAmerican Airlines
Deal found 4/27$292
This Copa Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/184:19 pmRDU - CTG
1 stop7h 42mCopa Airlines
mié. 5/216:20 amCTG - RDU
1 stop7h 09mCopa Airlines
Deal found 4/28$307
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/910:17 amRDU - CTG
1 stop26h 53mSpirit Airlines
mié. 6/181:15 pmCTG - RDU
1 stop19h 25mSpirit Airlines
Deal found 4/28$308
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/106:50 amRDU - BOG
1 stop13h 30mUnited Airlines
vie. 8/298:30 amBOG - RDU
1 stop30h 17mUnited Airlines
Deal found 4/28$310
This Copa Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/114:20 pmRDU - BOG
1 stop8h 46mCopa Airlines
mié. 6/184:59 amBOG - RDU
1 stop8h 30mCopa Airlines
Deal found 4/28$319
This LATAM Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/297:35 amRDU - CTG
1 stop6h 44mLATAM Airlines
jue. 5/85:12 amCTG - RDU
2 stops13h 37mLATAM Airlines
Deal found 4/28$321
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/98:27 pmRDU - CTG
2 stops18h 43mAmerican Airlines
lun. 5/123:10 pmCTG - RDU
2 stops19h 45mAmerican Airlines
Deal found 4/28$323
This Copa Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/44:20 pmRDU - MDE
1 stop16h 57mCopa Airlines
dom. 6/86:40 amMDE - RDU
1 stop6h 49mCopa Airlines
Deal found 4/29$324
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/296:25 amRDU - CTG
1 stop7h 45mDelta
sáb. 8/92:30 pmCTG - RDU
1 stop8h 50mDelta
Deal found 4/29$334
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/1210:35 amRDU - BOG
1 stop27h 30mSpirit Airlines
jue. 6/192:00 pmBOG - RDU
1 stop17h 20mSpirit Airlines
Deal found 4/29$347

Cheapflights Fare Finder

Customize your flight search to find flights from Durham to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 29, 2025.
Use the filters below to find and compare flights from Durham to South America that are best for you.

Fly from

Durham

Fly to

South America

Route

Depart

Return

Price

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

jue. 5/22

7:10 am-7:50 pm

1 stop13h 40m

Bogotá El Dorado

sáb. 5/31

1:35 am-7:49 pm

1 stop17h 14m

$289

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

jue. 6/5

12:34 pm-8:10 pm

1 stop8h 36m

Bogotá El Dorado

lun. 6/9

7:00 am-4:17 pm

1 stop8h 17m

$290

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

dom. 5/18

4:19 pm-11:01 pm

1 stop7h 42m

Cartagena Rafael Nunez

mié. 5/21

6:20 am-2:29 pm

1 stop7h 09m

$307

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

lun. 6/9

10:17 am-12:10 pm

1 stop26h 53m

Cartagena Rafael Nunez

mié. 6/18

1:15 pm-9:40 am

1 stop19h 25m

$308

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

dom. 8/10

6:50 am-7:20 pm

1 stop13h 30m

Bogotá El Dorado

vie. 8/29

8:30 am-3:47 pm

1 stop30h 17m

$310

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

mié. 6/11

4:20 pm-12:06 am

1 stop8h 46m

Bogotá El Dorado

mié. 6/18

4:59 am-2:29 pm

1 stop8h 30m

$319

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

vie. 5/9

6:43 am-2:10 pm

1 stop8h 27m

Cartagena Rafael Nunez

lun. 5/12

3:10 pm-10:28 am

2 stops18h 18m

$323

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

mié. 6/4

4:20 pm-8:17 am

1 stop16h 57m

Medellín Jose Maria Cordova Intl

dom. 6/8

6:40 am-2:29 pm

1 stop6h 49m

$324

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

mar. 7/29

6:25 am-1:10 pm

1 stop7h 45m

Cartagena Rafael Nunez

sáb. 8/9

2:30 pm-12:20 am

1 stop8h 50m

$334

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

mié. 6/11

11:12 am-9:17 pm

2 stops11h 05m

Bogotá El Dorado

mié. 6/18

6:30 am-6:40 pm

1 stop11h 10m

$335

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 60 results
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Best time to book a flight from Durham to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to South America

What is the cheapest month to book a flight from Durham to South America?

Currently, May is the cheapest month in which you can book a flight from Durham to South America (average of $359). Flying from Durham to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SA?

Find hourly flight availability from Durham to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 29, 2025.

When flying from Durham to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated abril 29, 2025.
Delta
8.0
Very good
7,936 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,936 reviews
Delta
8.0
Very good
7,936 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,767 reviews
Delta
8.0
Very good
7,936 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.5
Good
1,411 reviews
Delta
8.0
Very good
7,936 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Aeromexico
7.5
Good
1,698 reviews
Delta
8.0
Very good
7,936 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,936 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Durham to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Durham to South America one-way?

    The cheapest airlines for a one-way flight from Durham to South America are Copa Airlines ($146), United Airlines ($154), and American Airlines ($155).

  • What are the most popular routes from Durham to South America?

    While some choose either Raleigh-Durham - Medellín Jose Maria Cordova Intl or Raleigh-Durham - Bogotá El Dorado, Raleigh-Durham - Lima J Chavez Intl is the most popular route from Durham to South America.

  • Can I find deals for flights from Durham to South America that include hotel bookings?

    Yes. In addition to deals on Durham to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to South America.

  • Can I find deals for business class flights from Durham to South America?

    Yes. Cheapflights offers flight deals from Durham to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to South America?

    Currently, May is the cheapest month in which you can book a flight from Durham to South America (average of $359). Flying from Durham to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 9 airlines flying from Durham to South America

Discover the top 9 airlines that operate flights from Durham to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$232Average$700FlexibilityNo cancel feeOn-time69%
AviancaCheapest$244Average$669FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$256Average$556FlexibilityNo cancel feeOn-time70%
Spirit AirlinesCheapest$261Average$676FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$288Average$669FlexibilityNo cancel feeOn-time81%
DeltaCheapest$288Average$779FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$314Average$857FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$386Average$560FlexibilityNo cancel feeOn-time62%
GOLCheapest$451Average$741FlexibilityNo cancel feeOn-time74%

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