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South America

$99+ Cheap flights from Durham, NC to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/23. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — BOG
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Durham to South America

Keep the following information in mind while searching for Durham to South America flight deals. Data was last updated July 31, 2025.

Round-trip from

$231
(CheapOair)

One-way from

$99
(SmartFares)

Popular in

January

Cheapest in

March

Average price

$723
From Durham to South America
Search Deals
One-way flight from Durham to South America
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($147 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Durham to South America

Cheapest flights from Durham to South America
Explore the most affordable flight options available from Durham to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/119:23 amRDU - MDE
1 stop16h 05mSpirit Airlines
Sun 9/141:24 amMDE - RDU
1 stop12h 11mSpirit Airlines
Deal found 7/30$234
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/314:22 pmRDU - CTG
1 stop7h 36mCopa Airlines
Sun 9/76:20 amCTG - RDU
1 stop7h 07mCopa Airlines
Deal found 7/31$274
This FlightHub deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/186:25 amRDU - BOG
1 stop13h 50mLATAM Airlines
Mon 9/2210:15 amBOG - RDU
1 stop7h 52mLATAM Airlines
Deal found 7/29$282
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/194:21 pmRDU - BOG
1 stop7h 19mCopa Airlines
Sun 9/216:10 amBOG - RDU
1 stop7h 17mCopa Airlines
Deal found 7/31$284
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/137:45 amRDU - CTG
1 stop6h 31mDelta
Sat 9/202:33 pmCTG - RDU
1 stop7h 05mDelta
Deal found 7/30$286
This CheapOair deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/79:23 amRDU - BOG
1 stop28h 47mSpirit Airlines
Wed 10/12:05 pmBOG - RDU
1 stop23h 30mSpirit Airlines
Deal found 7/29$288
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/256:00 amRDU - CTG
1 stop9h 04mAmerican Airlines
Wed 9/31:25 pmCTG - RDU
2 stops19h 34mAmerican Airlines
Deal found 7/30$290
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/261:30 pmRDU - BOG
2 stops16h 24mUnited Airlines
Thu 9/118:30 amBOG - RDU
2 stops14h 21mUnited Airlines
Deal found 7/31$294
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/188:03 pmRDU - BOG
2 stops16h 57mDelta
Sat 9/202:55 pmBOG - RDU
1 stop18h 03mDelta
Deal found 7/30$296
This CheapOair deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/257:56 pmRDU - CTG
1 stop17h 32mSpirit Airlines
Wed 9/31:36 pmCTG - RDU
1 stop23h 59mSpirit Airlines
Deal found 7/30$301
This FlightHub deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2512:35 pmRDU - UIO
1 stop7h 24mLATAM Airlines
Mon 10/279:11 amUIO - RDU
1 stop10h 14mLATAM Airlines
Deal found 7/30$304
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/178:00 amRDU - BOG
2 stops14h 17mAmerican Airlines
Wed 9/246:30 amBOG - RDU
1 stop16h 15mAmerican Airlines
Deal found 7/31$304

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Durham to South America that are best for you.

Fly from

Durham

Fly to

South America

Route

Depart

Return

Price

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Thu 9/11

9:23 am-12:28 am

1 stop16h 05m

Medellín Jose Maria Cordova Intl

Sun 9/14

1:24 am-2:35 pm

1 stop12h 11m

$234

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Fri 10/3

4:19 pm-8:41 am

1 stop17h 22m

Cartagena Rafael Nunez

Sun 10/12

6:21 am-2:27 pm

1 stop7h 06m

$274

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Thu 9/18

6:25 am-7:15 pm

1 stop13h 50m

Bogotá El Dorado

Mon 9/22

10:15 am-7:07 pm

1 stop7h 52m

$282

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Fri 9/19

4:21 pm-10:40 pm

1 stop7h 19m

Bogotá El Dorado

Sun 9/21

6:10 am-2:27 pm

1 stop7h 17m

$284

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sat 9/6

7:45 am-1:18 pm

1 stop6h 33m

Cartagena Rafael Nunez

Sat 9/13

2:33 pm-8:51 am

1 stop17h 18m

$286

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Sun 9/7

9:23 am-1:10 pm

1 stop28h 47m

Bogotá El Dorado

Wed 10/1

2:05 pm-2:35 pm

1 stop23h 30m

$288

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Fri 8/22

7:53 pm-2:04 pm

1 stop19h 11m

Cartagena Rafael Nunez

Fri 8/29

1:25 pm-8:51 am

2 stops18h 26m

$289

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Wed 10/1

9:56 am-7:32 pm

2 stops34h 36m

Cartagena Rafael Nunez

Sat 10/4

2:33 pm-8:51 am

1 stop17h 18m

$291

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Tue 8/26

1:30 pm-4:54 am

2 stops16h 24m

Bogotá El Dorado

Thu 9/11

8:30 am-11:51 pm

2 stops14h 21m

$294

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sun 9/28

9:23 am-12:23 pm

1 stop28h 00m

Cartagena Rafael Nunez

Wed 10/1

1:29 pm-2:35 pm

1 stop24h 06m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Showing 1-10 of 60 results
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Best time to book a flight from Durham to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to South America

What is the cheapest month to book a flight from Durham to South America?

Currently, May is the cheapest month in which you can book a flight from Durham to South America (average of $359). Flying from Durham to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SA?

Find hourly flight availability from Durham to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

When flying from Durham to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated July 31, 2025.
Peruse reviews from past customers who have flown with Azul, Delta, and LATAM Airlines from Durham to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Azul
8.0
Very good
802 reviews

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

7.9

Food

7.1

Overall

8.0

Reviews

1 / 15
10.0
Excellent

Dean,Jul 2025

CNF - FLL

The touch screens on the aircraft (A330 Neo) were terrible... they did not function properly, and the hand controller did not work much better. With much effort, I was able to view some content that I wanted to see. The "Map" function on the system was inoperative, as well. The only information you could get was the basic info about the flight (altitude, temperature, time-to-destination). Considering that this route takes you over top of one of the most amazing countries/regions in the world, it would have been nice to see the landmarks on a map.
Azul
8.0
Very good
802 reviews
Azul
8.0
Very good
802 reviews

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

7.9

Food

7.1

Overall

8.0

Reviews

1 / 15
10.0
Excellent

Dean,Jul 2025

CNF - FLL

The touch screens on the aircraft (A330 Neo) were terrible... they did not function properly, and the hand controller did not work much better. With much effort, I was able to view some content that I wanted to see. The "Map" function on the system was inoperative, as well. The only information you could get was the basic info about the flight (altitude, temperature, time-to-destination). Considering that this route takes you over top of one of the most amazing countries/regions in the world, it would have been nice to see the landmarks on a map.
Delta
8.0
Very good
7,981 reviews
Azul
8.0
Very good
802 reviews

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

7.9

Food

7.1

Overall

8.0

Reviews

1 / 15
10.0
Excellent

Dean,Jul 2025

CNF - FLL

The touch screens on the aircraft (A330 Neo) were terrible... they did not function properly, and the hand controller did not work much better. With much effort, I was able to view some content that I wanted to see. The "Map" function on the system was inoperative, as well. The only information you could get was the basic info about the flight (altitude, temperature, time-to-destination). Considering that this route takes you over top of one of the most amazing countries/regions in the world, it would have been nice to see the landmarks on a map.
LATAM Airlines
7.5
Good
1,822 reviews
Azul
8.0
Very good
802 reviews

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

7.9

Food

7.1

Overall

8.0

Reviews

1 / 15
10.0
Excellent

Dean,Jul 2025

CNF - FLL

The touch screens on the aircraft (A330 Neo) were terrible... they did not function properly, and the hand controller did not work much better. With much effort, I was able to view some content that I wanted to see. The "Map" function on the system was inoperative, as well. The only information you could get was the basic info about the flight (altitude, temperature, time-to-destination). Considering that this route takes you over top of one of the most amazing countries/regions in the world, it would have been nice to see the landmarks on a map.
Copa Airlines
7.5
Good
1,493 reviews
Azul
8.0
Very good
802 reviews

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

7.9

Food

7.1

Overall

8.0

Reviews

1 / 15
10.0
Excellent

Dean,Jul 2025

CNF - FLL

The touch screens on the aircraft (A330 Neo) were terrible... they did not function properly, and the hand controller did not work much better. With much effort, I was able to view some content that I wanted to see. The "Map" function on the system was inoperative, as well. The only information you could get was the basic info about the flight (altitude, temperature, time-to-destination). Considering that this route takes you over top of one of the most amazing countries/regions in the world, it would have been nice to see the landmarks on a map.
United Airlines
7.4
Good
8,900 reviews
Azul
8.0
Very good
802 reviews

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

7.9

Food

7.1

Overall

8.0

Reviews

1 / 15
10.0
Excellent

Dean,Jul 2025

CNF - FLL

The touch screens on the aircraft (A330 Neo) were terrible... they did not function properly, and the hand controller did not work much better. With much effort, I was able to view some content that I wanted to see. The "Map" function on the system was inoperative, as well. The only information you could get was the basic info about the flight (altitude, temperature, time-to-destination). Considering that this route takes you over top of one of the most amazing countries/regions in the world, it would have been nice to see the landmarks on a map.

Related info for your journey

Find useful and relevant information for your journey from Durham to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Durham to South America one-way?

    The cheapest airlines for a one-way flight from Durham to South America are Spirit Airlines ($99), Copa Airlines ($156), and United Airlines ($168).

  • What are the most popular routes from Durham to South America?

    While some choose either Raleigh-Durham - Bogotá El Dorado or Raleigh-Durham - Sao Paulo Guarulhos Intl, Raleigh-Durham - Medellín Jose Maria Cordova Intl is the most popular route from Durham to South America.

  • Can I find deals for flights from Durham to South America that include hotel bookings?

    Yes. In addition to deals on Durham to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to South America.

  • Can I find deals for business class flights from Durham to South America?

    Yes. Cheapflights offers flight deals from Durham to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to South America?

    Currently, May is the cheapest month in which you can book a flight from Durham to South America (average of $359). Flying from Durham to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 8 airlines flying from Durham to South America

Discover the top 8 airlines that operate flights from Durham to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$189Average$776FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$222Average$757FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$225Average$628FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$249Average$523FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$302Average$745FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$311Average$671FlexibilityNo cancel feeOn-time69%
JetBlueCheapest$393Average$561FlexibilityNo cancel feeOn-time62%
GOLCheapest$481Average$620FlexibilityNo cancel feeOn-time74%

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