In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

What are the most popular routes from Detroit Metropolitan Wayne County Airport to South America?

While some choose either Detroit Metropolitan Wayne County - Lima J Chavez Intl or Detroit Metropolitan Wayne County - Medellín Jose Maria Cordova Intl, Detroit Metropolitan Wayne County - Sao Paulo Guarulhos Intl is the most popular route from Detroit Metropolitan Wayne County Airport to South America.

What are the most popular airlines that fly from Detroit Metropolitan Wayne County Airport to South America?

The most popular airlines flying from Detroit Metropolitan Wayne County Airport to South America are Delta, Spirit Airlines and American Airlines. Something to consider prior to booking your flight.

What airport do you fly from for flights from Detroit to South America?

Detroit Metropolitan Wayne County (DTW), located 17.3 mi from the city center, is the airport you fly out of when you book flights from Detroit to South America.

Can I find deals for flights from Detroit to South America that include hotel bookings?

Yes. In addition to deals on Detroit to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Detroit to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to South America.

Can I find deals for business class flights from Detroit to South America?

Yes. Cheapflights offers flight deals from Detroit to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$107+ Cheap Flights from Detroit Metropolitan Wayne County Airport to South America

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Detroit to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Detroit to South America

Cheapest flights from Detroit to South America
Explore the most affordable flight options available from Detroit to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on outubro 28, 2025.

sáb 11/158:05 pmDTW - CTG

1 stop17h 10mSpirit Airlines

sáb 11/222:30 pmCTG - DTW

1 stop9h 24mSpirit Airlines

Deal found 10/27

$293

ter 11/117:00 amDTW - CTG

2 stops30h 15mSpirit Airlines

sáb 11/222:30 pmCTG - DTW

1 stop9h 24mSpirit Airlines

Deal found 10/25

$306

ter 11/117:00 amDTW - CTG

2 stops30h 15mSpirit Airlines

qua 11/192:20 pmCTG - DTW

1 stop8h 26mSpirit Airlines

Deal found 10/25

$324

sex 11/148:05 pmDTW - BOG

1 stop18h 05mSpirit Airlines

seg 12/13:17 pmBOG - DTW

2 stops26h 16mSpirit Airlines

Deal found 10/28

$325

ter 11/118:05 pmDTW - BOG

1 stop18h 05mSpirit Airlines

sáb 11/223:17 pmBOG - DTW

1 stop8h 37mSpirit Airlines

Deal found 10/27

$326

ter 11/118:05 pmDTW - BOG

1 stop18h 05mSpirit Airlines

qui 11/203:17 pmBOG - DTW

1 stop8h 37mSpirit Airlines

Deal found 10/27

$328

sáb 11/156:29 pmDTW - CTG

2 stops18h 46mMultiple Airlines

sáb 11/222:30 pmCTG - DTW

1 stop9h 24mMultiple Airlines

Deal found 10/26

$329

qua 11/126:10 amDTW - CTG

1 stop7h 05mSpirit Airlines

qua 11/192:20 pmCTG - DTW

1 stop9h 34mSpirit Airlines

Deal found 10/25

$331

ter 11/118:05 pmDTW - BOG

1 stop18h 05mMultiple Airlines

qui 11/203:17 pmBOG - DTW

2 stops16h 49mMultiple Airlines

Deal found 10/27

$331

seg 12/19:53 pmDTW - BOG

1 stop15h 07mSpirit Airlines

seg 12/83:05 pmBOG - DTW

1 stop9h 14mSpirit Airlines

Deal found 10/27

$339

seg 11/107:17 pmDTW - BOG

2 stops18h 53mSpirit Airlines

qui 11/201:55 pmBOG - DTW

1 stop9h 51mSpirit Airlines

Deal found 10/27

$340

sáb 11/157:17 pmDTW - BOG

2 stops18h 53mSpirit Airlines

ter 12/21:55 pmBOG - DTW

1 stop9h 51mSpirit Airlines

Deal found 10/28

$345

Best flights from Detroit to South America
Discover carefully curated flight deals from Detroit to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated outubro 28, 2025.

sáb 1/246:11 amDTW - CTG

1 stop6h 57mSpirit Airlines

sáb 2/72:16 pmCTG - DTW

1 stop10h 09mSpirit Airlines

Deal found 10/26

$326

qui 11/136:55 pmDTW - BOG

2 stops18h 05mMultiple Airlines

ter 12/21:55 pmBOG - DTW

1 stop9h 51mMultiple Airlines

Deal found 10/28

$346

dom 2/19:00 amDTW - BOG

2 stops13h 55mCopa Airlines

sex 2/274:45 amBOG - DTW

2 stops15h 32mCopa Airlines

Deal found 10/25

$569

ter 3/175:20 amDTW - BOG

1 stop15h 10mDelta

qui 3/263:55 pmBOG - DTW

1 stop18h 20mDelta

Deal found 10/26

$603

qui 1/226:11 amDTW - CTG

1 stop6h 57mSpirit Airlines

seg 1/262:16 pmCTG - DTW

1 stop10h 09mSpirit Airlines

Deal found 10/28

$333

ter 3/36:15 amDTW - LIM

1 stop17h 40mUnited Airlines

ter 3/101:30 amLIM - DTW

1 stop21h 29mUnited Airlines

Deal found 10/27

$680

ter 3/36:00 pmDTW - LIM

1 stop11h 10mAmerican Airlines

seg 3/231:20 amLIM - DTW

2 stops12h 27mAmerican Airlines

Deal found 10/27

$685

qua 11/126:10 amDTW - MDE

1 stop7h 53mSpirit Airlines

dom 12/72:05 amMDE - DTW

1 stop22h 14mSpirit Airlines

Deal found 10/28

$346

sáb 11/158:05 pmDTW - CTG

1 stop17h 10mMultiple Airlines

sex 11/214:50 amCTG - DTW

2 stops19h 04mMultiple Airlines

Deal found 10/26

$414

qua 1/1412:04 pmDTW - GIG

2 stops20h 11mGOL

sex 1/236:00 amGIG - DTW

2 stops19h 57mGOL

Deal found 10/26

$871

dom 12/147:42 pmDTW - MDE

1 stop18h 15mSpirit Airlines

ter 12/162:05 amMDE - DTW

1 stop8h 03mSpirit Airlines

Deal found 10/27

$360

qua 11/266:15 pmDTW - GIG

2 stops18h 55mAir Canada

dom 12/79:00 pmGIG - DTW

1 stop22h 35mAir Canada

Deal found 10/27

$945

sáb 11/158:05 pmDTW - BOG

1 stop18h 05mSpirit Airlines

ter 12/21:55 pmBOG - DTW

1 stop9h 51mSpirit Airlines

Deal found 10/28

$361

sex 11/2110:20 amDTW - GRU

1 stop17h 20mLATAM Airlines

dom 11/309:15 pmGRU - DTW

1 stop14h 11mLATAM Airlines

Deal found 10/27

$1,099

dom 12/77:42 pmDTW - MDE

1 stop15h 13mSpirit Airlines

seg 12/223:10 pmMDE - DTW

1 stop30h 01mSpirit Airlines

Deal found 10/26

$380

ter 12/26:35 amDTW - UIO

2 stops17h 15mMultiple Airlines

seg 12/83:30 amUIO - DTW

2 stops18h 19mMultiple Airlines

Deal found 10/25

$520

sex 12/52:50 pmDTW - CTG

2 stops22h 20mSpirit Airlines

dom 12/142:15 pmCTG - DTW

2 stops17h 52mSpirit Airlines

Deal found 10/26

$383

ter 11/47:00 amDTW - VCP

2 stops20h 35mMultiple Airlines

ter 11/1111:20 pmVCP - DTW

2 stops25h 38mMultiple Airlines

Deal found 10/25

$522

seg 3/211:00 amDTW - LIM

1 stop12h 55mUnited Airlines

qua 3/111:30 amLIM - DTW

1 stop21h 29mUnited Airlines

Deal found 10/27

$680

qua 11/128:05 pmDTW - BOG

1 stop18h 05mSpirit Airlines

seg 12/13:17 pmBOG - DTW

1 stop19h 00mSpirit Airlines

Deal found 10/28

$386

qui 2/268:20 pmDTW - UIO

2 stops16h 50mMultiple Airlines

seg 3/23:55 pmUIO - DTW

2 stops18h 10mMultiple Airlines

Deal found 10/28

$525

seg 3/26:15 amDTW - LIM

1 stop17h 40mUnited Airlines

seg 3/161:30 amLIM - DTW

1 stop21h 29mUnited Airlines

Deal found 10/27

$680

ter 11/47:00 amDTW - VCP

2 stops20h 35mMultiple Airlines

seg 11/1011:20 pmVCP - DTW

2 stops21h 21mMultiple Airlines

Deal found 10/26

$525

sáb 12/136:00 amDTW - CTG

1 stop7h 10mSpirit Airlines

sex 12/192:15 pmCTG - DTW

1 stop9h 44mSpirit Airlines

Deal found 10/28

$395

qua 3/49:00 amDTW - LIM

1 stop13h 15mUnited Airlines

seg 3/161:30 amLIM - DTW

1 stop21h 29mUnited Airlines

Deal found 10/27

$680

qui 11/139:39 pmDTW - BOG

2 stops16h 31mSpirit Airlines

seg 12/13:17 pmBOG - DTW

1 stop19h 00mSpirit Airlines

Deal found 10/28

$397

qua 12/1011:48 amDTW - SCL

1 stop17h 57mAmerican Airlines

qua 12/1711:15 pmSCL - DTW

1 stop21h 20mAmerican Airlines

Deal found 10/26

$864

ter 11/47:00 amDTW - VCP

2 stops20h 35mMultiple Airlines

dom 11/911:20 pmVCP - DTW

2 stops15h 12mMultiple Airlines

Deal found 10/26

$542

sex 1/1612:04 pmDTW - GIG

2 stops20h 11mGOL

dom 1/256:10 pmGIG - DTW

2 stops19h 15mGOL

Deal found 10/26

$881

dom 2/19:20 pmDTW - BOG

2 stops15h 42mSpirit Airlines

sáb 2/281:57 pmBOG - DTW

1 stop10h 22mSpirit Airlines

Deal found 10/28

$397

Last-minute flights from Detroit to South America
Discover last-minute flight deals from Detroit to South America. Data last updated outubro 28, 2025 and is based on user searches.

seg 11/107:17 pmDTW - BOG

2 stops18h 53mSpirit Airlines

qui 11/201:55 pmBOG - DTW

1 stop9h 51mSpirit Airlines

Deal found 10/27

$340

seg 11/107:17 pmDTW - BOG

2 stops18h 53mSpirit Airlines

sex 11/213:17 pmBOG - DTW

1 stop30h 41mSpirit Airlines

Deal found 10/27

$346

ter 11/117:00 amDTW - CTG

2 stops30h 15mSpirit Airlines

qui 11/202:30 pmCTG - DTW

1 stop9h 24mSpirit Airlines

Deal found 10/25

$306

ter 11/117:00 amDTW - CTG

2 stops30h 15mSpirit Airlines

qua 11/192:20 pmCTG - DTW

1 stop8h 26mSpirit Airlines

Deal found 10/25

$324

ter 11/118:05 pmDTW - BOG

1 stop18h 05mSpirit Airlines

sáb 11/223:17 pmBOG - DTW

1 stop8h 37mSpirit Airlines

Deal found 10/27

$326

ter 11/118:05 pmDTW - BOG

1 stop18h 05mSpirit Airlines

qui 11/203:17 pmBOG - DTW

1 stop8h 37mSpirit Airlines

Deal found 10/27

$328

ter 11/118:05 pmDTW - BOG

1 stop18h 05mMultiple Airlines

qui 11/203:17 pmBOG - DTW

2 stops16h 49mMultiple Airlines

Deal found 10/27

$331

qua 11/126:10 amDTW - CTG

1 stop7h 05mSpirit Airlines

qua 11/192:20 pmCTG - DTW

1 stop9h 34mSpirit Airlines

Deal found 10/25

$331

sex 11/148:05 pmDTW - BOG

1 stop18h 05mSpirit Airlines

seg 12/13:17 pmBOG - DTW

2 stops26h 16mSpirit Airlines

Deal found 10/28

$325

sáb 11/158:05 pmDTW - CTG

1 stop17h 10mSpirit Airlines

sáb 11/222:30 pmCTG - DTW

1 stop9h 24mSpirit Airlines

Deal found 10/27

$293

sáb 11/156:29 pmDTW - CTG

2 stops18h 46mMultiple Airlines

sáb 11/222:30 pmCTG - DTW

1 stop9h 24mMultiple Airlines

Deal found 10/26

$329

sáb 11/157:17 pmDTW - BOG

2 stops18h 53mSpirit Airlines

ter 12/21:55 pmBOG - DTW

1 stop9h 51mSpirit Airlines

Deal found 10/28

$345

One-way flights from Detroit to South America
Search for one-way flight options from Detroit to South America. Find affordable one-way fares based on user searches. Data last updated outubro 28, 2025.

seg 1/57:45 amDTW - MDE

1 stop17h 43mSpirit Airlines

Deal found 10/27

$107

sáb 11/157:00 amDTW - MDE

2 stops17h 57mSpirit Airlines

Deal found 10/27

$118

dom 11/166:10 amDTW - BOG

1 stop8h 00mSpirit Airlines

Deal found 10/26

$128

seg 1/263:15 pmDTW - BOG

1 stop21h 47mSpirit Airlines

Deal found 10/28

$135

qua 12/316:00 amDTW - CTG

1 stop7h 10mSpirit Airlines

Deal found 10/28

$137

qua 11/127:17 pmDTW - BOG

2 stops18h 53mSpirit Airlines

Deal found 10/26

$137

sáb 12/62:50 pmDTW - CTG

2 stops22h 20mSpirit Airlines

Deal found 10/27

$138

sex 1/26:00 amDTW - CTG

1 stop7h 10mSpirit Airlines

Deal found 10/28

$140

qua 12/39:53 pmDTW - BOG

1 stop14h 59mSpirit Airlines

Deal found 10/26

$142

seg 11/107:00 amDTW - BOG

3 stops23h 29mMultiple Airlines

Deal found 10/26

$150

qua 11/127:00 amDTW - BOG

3 stops22h 40mMultiple Airlines

Deal found 10/26

$153

seg 12/157:42 pmDTW - BOG

1 stop17h 10mSpirit Airlines

Deal found 10/27

$159

Cheap flight deals from Detroit to South America

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$291 (Orbitz)
One-way from	$107 (Cheapflightsfares)
Popular in	January
Cheapest in	April
Average price	$1,141

Provider with most accurate pricing for Detroit (DTT)-Sao Paulo (SAO) flight deals.

Search Deals

Provider most trusted by Cheapflights users for Detroit (DTT)-Sao Paulo (SAO) flights.

Search Deals

From Detroit Metropolitan Wayne County to South America

Search Deals

One-way flight from Detroit Metropolitan Wayne County to South America

Search Deals

Highest demand for flights based on searches. 19% potential increase in price ($269 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 6% potential price decrease ($70 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in October 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

sáb 1/24

6:11 am-1:08 pm

1 stop6h 57m

Cartagena Rafael Nunez

sáb 2/7

2:16 pm-12:25 am

1 stop10h 09m

$326

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

qui 1/22

6:11 am-1:08 pm

1 stop6h 57m

Cartagena Rafael Nunez

seg 1/26

2:16 pm-12:25 am

1 stop10h 09m

$333

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

qui 11/13

6:55 pm-1:00 pm

2 stops18h 05m

Bogotá El Dorado

ter 12/2

1:55 pm-11:46 pm

1 stop9h 51m

$346

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

qua 11/12

6:10 am-2:03 pm

1 stop7h 53m

Medellín Jose Maria Cordova Intl

dom 12/7

2:05 am-12:19 am

1 stop22h 14m

$346

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

dom 12/14

7:42 pm-1:57 pm

1 stop18h 15m

Medellín Jose Maria Cordova Intl

ter 12/16

2:05 am-10:08 am

1 stop8h 03m

$360

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

sáb 11/15

8:05 pm-2:10 pm

1 stop18h 05m

Bogotá El Dorado

ter 12/2

1:55 pm-11:46 pm

1 stop9h 51m

$361

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

dom 12/7

7:42 pm-10:55 am

1 stop15h 13m

Medellín Jose Maria Cordova Intl

seg 12/22

3:10 pm-9:11 pm

1 stop30h 01m

$380

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

sex 12/5

2:50 pm-1:10 pm

2 stops22h 20m

Cartagena Rafael Nunez

dom 12/14

2:15 pm-8:07 am

2 stops17h 52m

$383

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

qua 11/12

8:05 pm-2:10 pm

1 stop18h 05m

Bogotá El Dorado

seg 12/1

3:17 pm-10:17 am

1 stop19h 00m

$386

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

sáb 12/13

6:00 am-1:10 pm

1 stop7h 10m

Cartagena Rafael Nunez

sex 12/19

2:15 pm-11:59 pm

1 stop9h 44m

$395

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 60 results

...

Best time to book a flight from Detroit to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Detroit with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to South America

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to South America?

Currently, May is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to South America (average of $239). Flying from Detroit Metropolitan Wayne County Airport to South America in March is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to SA?

It’s typically best to fly out from Detroit Metropolitan Wayne County Airport to South America in the evening. Doing so could potentially save you 23% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to South America?

Travelers seeking maximum savings on their Detroit Metropolitan Wayne County Airport to South America flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Peruse reviews from past customers who have flown with Delta, LATAM Airlines, and American Airlines from Detroit Metropolitan Wayne County Airport to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

7,994 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Delta

7.9

Good

7,994 reviews

Delta

7.9

Good

7,994 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

LATAM Airlines

7.5

Good

1,871 reviews

Delta

7.9

Good

7,994 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

American Airlines

7.2

Good

11,032 reviews

Delta

7.9

Good

7,994 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

Air Canada

7.1

Good

10,371 reviews

Delta

7.9

Good

7,994 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

Spirit Airlines

6.3

Okay

8,114 reviews

Delta

7.9

Good

7,994 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

Related info for your journey

What airport do you fly from for flights from Detroit to South America?
Detroit Metropolitan Wayne County (DTW), located 17.3 mi from the city center, is the airport you fly out of when you book flights from Detroit to South America.
How long is the flight from Detroit Metropolitan Wayne County Airport to South America?
For as low as $326, Spirit Airlines can have you in South America from Detroit Metropolitan Wayne County Airport in 6h 57m. The distance from Detroit Metropolitan Wayne County Airport to South America is about 2245 mi.
What are the most popular routes from Detroit Metropolitan Wayne County Airport to South America?
While some choose either Detroit Metropolitan Wayne County - Lima J Chavez Intl or Detroit Metropolitan Wayne County - Medellín Jose Maria Cordova Intl, Detroit Metropolitan Wayne County - Sao Paulo Guarulhos Intl is the most popular route from Detroit Metropolitan Wayne County Airport to South America.
Can I find deals for flights from Detroit to South America that include hotel bookings?
Yes. In addition to deals on Detroit to South America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Detroit to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to South America.
Can I find deals for business class flights from Detroit to South America?
Yes. Cheapflights offers flight deals from Detroit to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to South America?
Currently, May is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to South America (average of $239). Flying from Detroit Metropolitan Wayne County Airport to South America in March is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 7 airlines flying from Detroit to South America

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$104	Average$510	FlexibilityNo cancel fee	On-time65%
American Airlines	Cheapest$385	Average$977	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$527	Average$1,149	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$550	Average$980	FlexibilityNo cancel fee	On-time69%
Copa Airlines	Cheapest$583	Average$932	FlexibilityNo cancel fee	On-time70%
Air Canada	Cheapest$585	Average$841	FlexibilityNo cancel fee	On-time67%
LATAM Airlines	Cheapest$652	Average$1,250	FlexibilityNo cancel fee	On-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$107+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Detroit to South America with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Detroit to South America

Cheapest flights from Detroit to South AmericaExplore the most affordable flight options available from Detroit to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on outubro 28, 2025.

Explore the most affordable flight options available from Detroit to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on outubro 28, 2025.

Cheap flight deals from Detroit to South America

Keep the following information in mind while searching for Detroit to South America flight deals. Data was last updated outubro 28, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to South America that are best for you.

Best time to book a flight from Detroit to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Detroit with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to South America

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to South America?

What is the cheapest time of day to fly from DTW to SA?

Find hourly flight availability from Detroit to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated outubro 28, 2025.

What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to South America?

Use this chart to determine the cheapest time to fly round-trip from Detroit to South America. Price data was last updated on December 16, 2024.

Reviews of airlines servicing South America

Related info for your journey

Find useful and relevant information for your journey from Detroit to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Detroit to South America?

How long is the flight from Detroit Metropolitan Wayne County Airport to South America?

What are the most popular routes from Detroit Metropolitan Wayne County Airport to South America?

Can I find deals for flights from Detroit to South America that include hotel bookings?

How can I find direct flights from Detroit to South America?

Can I find deals for business class flights from Detroit to South America?

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to South America?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Detroit to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from Detroit to South America

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Detroit to South America
Explore the most affordable flight options available from Detroit to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on outubro 28, 2025.