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South America

$156+ Cheap flights from Denver (DEN) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/28. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — BOG
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Denver to South America

Keep the following information in mind while searching for Denver to South America flight deals. Data was last updated May 1, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$334
(Copa Airlines)

One-way from

$156
(Delta)

Popular in

December

Cheapest in

October

Average price

$1,040
Provider with most accurate pricing for Denver Intl-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Denver Intl-Sao Paulo (SAO) flights.
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From Denver Intl to South America
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One-way flight from Denver Intl to South America
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Highest demand for flights based on searches. 15% potential increase in price ($195 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($42 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Denver to South America

Cheapest flights from Denver to South America
Explore the most affordable flight options available from Denver to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Copa Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1310:42 pmDEN - CTG
1 stop14h 22mCopa Airlines
Wed 8/206:20 amCTG - DEN
1 stop12h 43mCopa Airlines
Deal found 4/30$334
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/37:20 amDEN - BOG
1 stop10h 55mDelta
Sat 5/102:55 pmBOG - DEN
1 stop18h 40mDelta
Deal found 4/30$343
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/154:40 pmDEN - CTG
1 stop19h 12mDelta
Sat 8/232:06 pmCTG - DEN
1 stop9h 13mDelta
Deal found 4/30$346
This LATAM Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/3012:55 amDEN - BOG
1 stop17h 20mLATAM Airlines
Wed 5/77:00 amBOG - DEN
2 stops15h 57mLATAM Airlines
Deal found 4/30$348
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/154:45 pmDEN - CTG
2 stops18h 40mAmerican Airlines
Sat 8/231:30 pmCTG - DEN
2 stops21h 15mAmerican Airlines
Deal found 4/30$350
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/57:45 amDEN - BOG
1 stop10h 35mUnited Airlines
Sun 5/1112:14 amBOG - DEN
1 stop23h 01mUnited Airlines
Deal found 4/30$350
This Copa Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/910:25 pmDEN - BOG
1 stop10h 04mCopa Airlines
Sat 5/174:59 amBOG - DEN
1 stop14h 18mCopa Airlines
Deal found 4/30$374
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3111:59 pmDEN - BOG
1 stop19h 16mAmerican Airlines
Fri 11/78:10 amBOG - DEN
1 stop15h 51mAmerican Airlines
Deal found 4/30$391
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/135:16 amDEN - CTG
2 stops26h 27mUnited Airlines
Wed 5/219:38 amCTG - DEN
2 stops15h 20mUnited Airlines
Deal found 4/30$408
This United deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/138:31 pmDEN - CTG
2 stops35h 10mMultiple Airlines
Wed 8/204:58 amCTG - DEN
2 stops18h 01mMultiple Airlines
Deal found 4/30$410
This Flightnetwork deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/110:25 pmDEN - MDE
1 stop14h 50mCopa Airlines
Wed 5/143:29 pmMDE - DEN
1 stop27h 48mCopa Airlines
Deal found 4/29$454
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/115:00 amDEN - MDE
2 stops14h 15mAmerican Airlines
Sat 5/176:00 amMDE - DEN
2 stops18h 59mAmerican Airlines
Deal found 4/29$457

Cheapflights Fare Finder

Customize your flight search to find flights from Denver to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Denver to South America that are best for you.

Fly from

Denver

Fly to

South America

Route

Depart

Return

Price

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Wed 8/13

10:42 pm-2:04 pm

1 stop14h 22m

Cartagena Rafael Nunez

Wed 8/20

6:20 am-6:03 pm

1 stop12h 43m

$334

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Wed 5/14

10:56 am-10:30 pm

1 stop10h 34m

Bogotá El Dorado

Thu 5/15

12:25 am-5:41 pm

1 stop18h 16m

$343

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Fri 8/15

4:40 pm-12:52 pm

1 stop19h 12m

Cartagena Rafael Nunez

Sat 8/23

2:06 pm-10:19 pm

1 stop9h 13m

$346

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Thu 6/5

6:00 am-8:10 pm

2 stops13h 10m

Bogotá El Dorado

Wed 7/2

10:45 am-10:29 pm

2 stops12h 44m

$347

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Thu 10/9

5:10 am-7:20 pm

1 stop13h 10m

Bogotá El Dorado

Sun 10/12

12:14 am-9:59 pm

1 stop22h 45m

$350

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Sun 8/31

11:52 pm-2:10 pm

1 stop13h 18m

Cartagena Rafael Nunez

Tue 9/9

1:55 pm-10:22 am

2 stops21h 27m

$350

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Tue 5/13

5:16 am-8:43 am

2 stops26h 27m

Cartagena Rafael Nunez

Wed 5/21

9:38 am-11:58 pm

2 stops15h 20m

$408

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Wed 8/13

8:31 pm-8:41 am

2 stops35h 10m

Cartagena Rafael Nunez

Wed 8/20

4:58 am-9:59 pm

2 stops18h 01m

$410

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Tue 6/3

9:40 am-10:55 am

2 stops24h 15m

Bogotá El Dorado

Tue 7/1

9:00 am-8:34 am

1 stop24h 34m

$420

DenverMedellín

DEN - MDE

DENMDE

Denver Intl

Sun 5/11

5:00 am-8:15 pm

2 stops14h 15m

Medellín Jose Maria Cordova Intl

Sat 5/17

6:00 am-11:59 pm

2 stops18h 59m

$457

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/1

Showing 1-10 of 60 results
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Best time to book a flight from Denver to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to South America

What is the cheapest month to book a flight from Denver to South America?

Currently, May is the cheapest month in which you can book a flight from Denver to South America (average of $359). Flying from Denver to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to SA?

Find hourly flight availability from Denver to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated May 1, 2025.
Azul
8.0
Very good
777 reviews

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Azul
8.0
Very good
777 reviews
Azul
8.0
Very good
777 reviews

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Delta
8.0
Very good
7,934 reviews
Azul
8.0
Very good
777 reviews

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Copa Airlines
7.5
Good
1,414 reviews
Azul
8.0
Very good
777 reviews

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Aeromexico
7.5
Good
1,698 reviews
Azul
8.0
Very good
777 reviews

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
LATAM Airlines
7.5
Good
1,767 reviews
Azul
8.0
Very good
777 reviews

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

Related info for your journey

Find useful and relevant information for your journey from Denver to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Denver to South America?

    Most people fly from Denver Intl (DEN) if they book a flight from Denver to South America. Denver Intl is conveniently located just 18.5 mi from Denver’s city center.

  • What are the cheapest airlines to fly from Denver to South America one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $156. However, be on the lookout for offers from Copa Airlines and American Airlines, as they are both options that can get you from Denver to South America for a low price.

  • What are the most popular routes from Denver to South America?

    The most popular route from Denver to South America is Denver Intl - Lima J Chavez Intl. You may also consider Denver Intl - Medellín Jose Maria Cordova Intl or Denver Intl - Sao Paulo Guarulhos Intl.

  • Can I find deals for flights from Denver to South America that include hotel bookings?

    Yes. In addition to deals on Denver to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to South America.

  • Can I find deals for business class flights from Denver to South America?

    Yes. Cheapflights offers flight deals from Denver to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to South America?

    Currently, May is the cheapest month in which you can book a flight from Denver to South America (average of $359). Flying from Denver to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Denver to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 10 airlines flying from Denver to South America

Discover the top 10 airlines that operate flights from Denver to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
VolarisCheapest$208Average$319FlexibilityNo cancel feeOn-time79%
DeltaCheapest$309Average$983FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$310Average$916FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$315Average$904FlexibilityNo cancel feeOn-time71%
AeromexicoCheapest$319Average$856FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$330Average$989FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$347Average$693FlexibilityNo cancel feeOn-time70%
Air CanadaCheapest$798Average$1,002FlexibilityNo cancel feeOn-time67%
GOLCheapest$823Average$1,232FlexibilityNo cancel feeOn-time74%
AzulCheapest$973Average$1,604FlexibilityNo cancel feeOn-time82%

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