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South America

$139+ Cheap flights from Denver (DEN) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — BOG
feb. 14 — feb. 211
sáb. 2/14
sáb. 2/21
1 adult, Economy
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Cheap flight deals from Denver to South America

Keep the following information in mind while searching for Denver to South America flight deals. Data was last updated enero 15, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$325
(Copa Airlines)

One-way from

$139
(Copa Airlines)

Popular in

December

Cheapest in

May

Average price

$884
Provider with most accurate pricing for Denver Intl-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Denver Intl-Sao Paulo (SAO) flights.
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From Denver Intl to South America
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One-way flight from Denver Intl to South America
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Highest demand for flights based on searches. 13% potential increase in price ($140 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Denver to South America

Cheapest flights from Denver to South America
Explore the most affordable flight options available from Denver to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 15, 2026.

This Copa Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/239:38 pm
DEN
-
CTG
1 stop9h 03m
Copa Airlines
sáb. 3/76:25 am
CTG
-
DEN
1 stop12h 51m
Copa Airlines
Deal found 1/14$325
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/2811:31 pm
DEN
-
CTG
1 stop13h 59m
American Airlines
mié. 3/111:27 pm
CTG
-
DEN
1 stop11h 32m
American Airlines
Deal found 1/14$328
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/62:14 pm
DEN
-
CTG
2 stops20h 55m
American Airlines
vie. 4/173:10 pm
CTG
-
DEN
2 stops21h 59m
American Airlines
Deal found 1/14$342
This Copa Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/239:38 pm
DEN
-
CTG
1 stop9h 03m
Copa Airlines
lun. 3/29:42 am
CTG
-
DEN
1 stop9h 34m
Copa Airlines
Deal found 1/13$345
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/2811:59 pm
DEN
-
CTG
2 stops13h 31m
American Airlines
mar. 3/101:27 pm
CTG
-
DEN
1 stop11h 32m
American Airlines
Deal found 1/14$365
This Copa Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/510:51 pm
DEN
-
CTG
1 stop8h 16m
Copa Airlines
vie. 4/179:46 am
CTG
-
DEN
1 stop9h 39m
Copa Airlines
Deal found 1/15$366
This Copa Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 1/199:38 pm
DEN
-
BOG
1 stop10h 32m
Copa Airlines
vie. 1/307:00 am
BOG
-
DEN
1 stop12h 16m
Copa Airlines
Deal found 1/14$367
This Copa Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/289:38 pm
DEN
-
CTG
1 stop9h 03m
Copa Airlines
mar. 3/106:25 am
CTG
-
DEN
1 stop12h 51m
Copa Airlines
Deal found 1/14$371
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/2411:59 pm
DEN
-
CTG
2 stops13h 31m
American Airlines
vie. 3/64:30 pm
CTG
-
DEN
1 stop9h 29m
American Airlines
Deal found 1/14$378
This Copa Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/2610:51 pm
DEN
-
CTG
1 stop8h 46m
Copa Airlines
sáb. 5/26:20 am
CTG
-
DEN
1 stop13h 05m
Copa Airlines
Deal found 1/14$385
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 1/289:38 pm
DEN
-
BOG
1 stop9h 47m
Copa Airlines
sáb. 2/710:00 am
BOG
-
DEN
1 stop9h 16m
Copa Airlines
Deal found 1/14$386
This Booking.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 1/289:38 pm
DEN
-
BOG
1 stop17h 48m
Copa Airlines
mar. 2/34:45 am
BOG
-
DEN
1 stop14h 31m
Copa Airlines
Deal found 1/14$390

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 15, 2026.
Use the filters below to find and compare flights from Denver to South America that are best for you.

Fly from

Denver

Fly to

South America

Route

Depart

Return

Price

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

lun. 2/23

9:38 pm-8:41 am

1 stop9h 03m

Cartagena Rafael Nunez

sáb. 3/7

9:42 am-5:16 pm

1 stop9h 34m

$325

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

sáb. 2/14

9:38 pm-8:06 am

1 stop8h 28m

Cartagena Rafael Nunez

sáb. 2/21

9:42 am-5:16 pm

1 stop9h 34m

$325

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

mar. 2/24

9:38 pm-8:41 am

1 stop9h 03m

Cartagena Rafael Nunez

vie. 3/6

9:22 am-5:16 pm

1 stop9h 54m

$325

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

lun. 4/6

4:43 pm-12:09 pm

2 stops18h 26m

Cartagena Rafael Nunez

vie. 4/17

3:10 pm-9:38 am

2 stops19h 28m

$342

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

lun. 2/23

9:38 pm-8:41 am

1 stop9h 03m

Cartagena Rafael Nunez

lun. 3/2

9:42 am-5:16 pm

1 stop9h 34m

$345

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

dom. 4/5

10:51 pm-8:07 am

1 stop8h 16m

Cartagena Rafael Nunez

vie. 4/17

9:46 am-6:25 pm

1 stop9h 39m

$366

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

sáb. 2/28

11:59 pm-3:30 pm

2 stops13h 31m

Cartagena Rafael Nunez

mar. 3/10

1:27 pm-8:20 am

2 stops19h 53m

$369

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

sáb. 2/28

9:38 pm-8:41 am

1 stop9h 03m

Cartagena Rafael Nunez

mar. 3/10

6:25 am-6:16 pm

1 stop12h 51m

$371

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

sáb. 2/28

9:38 pm-8:41 am

1 stop9h 03m

Cartagena Rafael Nunez

sáb. 3/7

9:42 am-5:16 pm

1 stop9h 34m

$371

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

mar. 2/24

11:59 pm-3:30 pm

2 stops13h 31m

Cartagena Rafael Nunez

vie. 3/6

4:30 pm-8:20 am

2 stops17h 50m

$383

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/14

Showing 1-10 of 60 results
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Best time to book a flight from Denver to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to South America

What is the cheapest month to book a flight from Denver to South America?

Currently, September is the cheapest month in which you can book a flight from Denver to South America (average of $237). Flying from Denver to South America in March is currently the most expensive (average of $342). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated enero 15, 2026.
Read reviews from past customers who have flown Delta, Copa Airlines, and LATAM Airlines from Denver to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,048 reviews

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,048 reviews
Delta
7.9
Good
8,048 reviews

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.6
Good
1,559 reviews
Delta
7.9
Good
8,048 reviews

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,904 reviews
Delta
7.9
Good
8,048 reviews

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,163 reviews
Delta
7.9
Good
8,048 reviews

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,130 reviews
Delta
7.9
Good
8,048 reviews

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Denver to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Denver to South America?

    Most people fly from Denver Intl (DEN) if they book a flight from Denver to South America. Denver Intl is conveniently located just 18.5 mi from Denver’s city center.

  • How long is the flight from Denver to South America?

    There are many flights that can get you from Denver to South America in 8h 16m. Fly via Copa Airlines, American Airlines, or United Airlines to get the fastest option. Denver and South America are separated by a distance of 3082 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Denver to South America one-way?

    The cheapest airline one-way is LATAM Airlines, with whom users have recently found tickets for as low as $151. However, be on the lookout for offers from Copa Airlines and United Airlines, as they are both options that can get you from Denver to South America for a low price.

  • What are the most popular routes from Denver to South America?

    The most popular route from Denver to South America is Denver Intl - Lima J Chavez Intl. You may also consider Denver Intl - Buenos Aires Ministro Pistarini or Denver Intl - Cartagena Rafael Nunez.

  • Can I find deals for flights from Denver to South America that include hotel bookings?

    Yes. In addition to deals on Denver to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to South America.

  • Can I find deals for business class flights from Denver to South America?

    Yes. Cheapflights offers flight deals from Denver to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to South America?

    Currently, September is the cheapest month in which you can book a flight from Denver to South America (average of $237). Flying from Denver to South America in March is currently the most expensive (average of $342). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Denver to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from Denver to South America

Discover the top 8 airlines that operate flights from Denver to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
VolarisCheapest$168Average$237FlexibilityNo cancel feeOn-time79%
DeltaCheapest$230Average$761FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$328Average$866FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$331Average$600FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$335Average$707FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$342Average$844FlexibilityNo cancel feeOn-time69%
AeromexicoCheapest$557Average$918FlexibilityNo cancel feeOn-timeN/A
Air CanadaCheapest$930Average$1,097FlexibilityNo cancel feeOn-time67%

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