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South America

$131+ Cheap flights from Denver (DEN) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — BOG
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
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Cheap flight deals from Denver to South America

Cheapest flights from Denver to South America
Explore the most affordable flight options available from Denver to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

This FlightHub deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:42 pmDEN - LIM
1 stop14h 18mLATAM Airlines
Tue 2/312:15 pmLIM - DEN
1 stop12h 35mLATAM Airlines
Deal found 12/14$468
This FlightHub deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:42 pmDEN - LIM
1 stop14h 18mLATAM Airlines
Mon 2/28:25 amLIM - DEN
2 stops16h 25mLATAM Airlines
Deal found 12/16$481
This LATAM Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:27 pmDEN - LIM
1 stop12h 23mLATAM Airlines
Mon 2/212:15 pmLIM - DEN
1 stop12h 35mLATAM Airlines
Deal found 12/14$487
This FlightHub deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:27 pmDEN - LIM
1 stop12h 23mLATAM Airlines
Tue 2/38:25 amLIM - DEN
2 stops16h 25mLATAM Airlines
Deal found 12/16$501
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3011:55 amDEN - LIM
1 stop18h 55mDelta
Tue 2/312:15 pmLIM - DEN
1 stop14h 13mDelta
Deal found 12/16$505
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:27 pmDEN - LIM
1 stop12h 23mMultiple Airlines
Mon 2/211:33 pmLIM - DEN
2 stops38h 30mMultiple Airlines
Deal found 12/16$506
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/275:00 amDEN - BOG
1 stop22h 10mUnited Airlines
Tue 12/308:15 amBOG - DEN
1 stop26h 03mUnited Airlines
Deal found 12/14$506
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/275:30 amDEN - LIM
1 stop25h 20mDelta
Fri 1/1611:40 pmLIM - DEN
1 stop21h 48mDelta
Deal found 12/16$511
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:45 amDEN - BOG
1 stop19h 25mUnited Airlines
Thu 1/18:15 amBOG - DEN
1 stop15h 51mUnited Airlines
Deal found 12/14$521
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:05 pmDEN - BOG
1 stop30h 05mUnited Airlines
Mon 12/298:15 amBOG - DEN
1 stop24h 26mUnited Airlines
Deal found 12/15$540
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:00 amDEN - BOG
1 stop15h 35mUnited Airlines
Tue 12/308:15 amBOG - DEN
1 stop26h 03mUnited Airlines
Deal found 12/14$542
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2911:59 pmDEN - CTG
2 stops19h 31mAmerican Airlines
Tue 1/134:30 pmCTG - DEN
2 stops23h 44mAmerican Airlines
Deal found 12/15$547

Find flight deals from Denver to South America

Keep the following information in mind while searching for Denver to South America flight deals. Data was last updated December 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$348
(American Airlines)

One-way from

$131
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$1,200
Provider with most accurate pricing for Denver Intl-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Sao Paulo (SAO) flights.
Search Deals
From Denver Intl to South America
Search Deals
One-way flight from Denver Intl to South America
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($155 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Denver to South America that are best for you.

Fly from

Denver

Fly to

South America

Route

Depart

Return

Price

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Wed 1/21

4:30 pm-10:35 pm

1 stop28h 05m

Bogotá El Dorado

Sat 1/31

8:15 am-7:55 pm

1 stop13h 40m

$350

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Wed 3/18

5:00 am-10:35 pm

1 stop16h 35m

Bogotá El Dorado

Sun 3/22

8:15 am-6:40 am

1 stop23h 25m

$350

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Thu 1/29

6:23 am-11:30 pm

2 stops15h 07m

Bogotá El Dorado

Thu 2/19

3:15 pm-11:59 pm

1 stop10h 44m

$358

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Wed 1/21

3:39 pm-10:35 pm

1 stop28h 56m

Bogotá El Dorado

Sun 2/1

1:30 am-11:41 pm

1 stop24h 11m

$358

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Thu 2/19

11:59 pm-12:47 pm

1 stop10h 48m

Bogotá El Dorado

Mon 2/23

1:45 pm-9:41 pm

2 stops33h 56m

$380

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Thu 3/19

7:45 am-8:05 pm

1 stop11h 20m

Bogotá El Dorado

Tue 3/24

7:50 am-6:17 pm

1 stop11h 27m

$381

DenverMedellín

DEN - MDE

DENMDE

Denver Intl

Tue 2/24

11:59 pm-1:55 pm

1 stop11h 56m

Medellín Jose Maria Cordova Intl

Sat 2/28

2:50 pm-8:19 am

2 stops19h 29m

$389

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Wed 1/21

7:20 am-10:10 pm

1 stop12h 50m

Bogotá El Dorado

Sun 2/1

11:55 pm-6:13 pm

1 stop20h 18m

$393

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Wed 4/8

7:05 am-8:10 pm

2 stops12h 05m

Bogotá El Dorado

Wed 4/15

11:00 am-11:51 pm

2 stops13h 51m

$396

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Wed 1/21

6:00 am-10:10 pm

2 stops14h 10m

Bogotá El Dorado

Sat 1/31

8:00 am-11:54 pm

1 stop17h 54m

$398

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 60 results
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Best time to book a flight from Denver to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to South America

What is the cheapest month to book a flight from Denver to South America?

Currently, September is the cheapest month in which you can book a flight from Denver to South America (average of $224). Flying from Denver to South America in August is currently the most expensive (average of $342). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to SA?

Find hourly flight availability from Denver to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 16, 2025.

It’s typically best to fly out from Denver to South America in the evening. Doing so could potentially save you 31% on the flight price compared to flying in the afternoon, which is usually more expensive.

What is the cheapest day to fly from Denver to South America?

Use this chart to determine the cheapest time to fly round-trip from Denver to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Denver to South America flight should consider departing on Thursday afternoons when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated December 16, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines, and LATAM Airlines from Denver to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,010 reviews

Food

7.3

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,010 reviews
Delta
7.9
Good
8,010 reviews

Food

7.3

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.6
Good
1,556 reviews
Delta
7.9
Good
8,010 reviews

Food

7.3

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,891 reviews
Delta
7.9
Good
8,010 reviews

Food

7.3

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,094 reviews
Delta
7.9
Good
8,010 reviews

Food

7.3

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,048 reviews
Delta
7.9
Good
8,010 reviews

Food

7.3

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Denver to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Denver to South America?

    Most people fly from Denver Intl (DEN) if they book a flight from Denver to South America. Denver Intl is conveniently located just 18.5 mi from Denver’s city center.

  • How long is the flight from Denver to South America?

    There are many flights that can get you from Denver to South America in 11h 47m. Fly via United Airlines, American Airlines, or Delta to get the fastest option. Denver and South America are separated by a distance of 2704 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Denver to South America one-way?

    The cheapest airline one-way is LATAM Airlines, with whom users have recently found tickets for as low as $151. However, be on the lookout for offers from Copa Airlines and United Airlines, as they are both options that can get you from Denver to South America for a low price.

  • What are the most popular routes from Denver to South America?

    The most popular route from Denver to South America is Denver Intl - Medellín Jose Maria Cordova Intl. You may also consider Denver Intl - Lima J Chavez Intl or Denver Intl - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from Denver to South America that include hotel bookings?

    Yes. In addition to deals on Denver to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to South America.

  • Can I find deals for business class flights from Denver to South America?

    Yes. Cheapflights offers flight deals from Denver to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to South America?

    Currently, September is the cheapest month in which you can book a flight from Denver to South America (average of $224). Flying from Denver to South America in August is currently the most expensive (average of $342). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Denver to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from Denver to South America

Discover the top 8 airlines that operate flights from Denver to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
VolarisCheapest$180Average$270FlexibilityNo cancel feeOn-time79%
American AirlinesCheapest$323Average$948FlexibilityNo cancel feeOn-time71%
DeltaCheapest$329Average$899FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$331Average$633FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$331Average$740FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$341Average$915FlexibilityNo cancel feeOn-time69%
AeromexicoCheapest$492Average$906FlexibilityNo cancel feeOn-timeN/A
Air CanadaCheapest$930Average$1,097FlexibilityNo cancel feeOn-time67%

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