HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South America

$169+ Cheap flights from Cleveland (CLE) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — BOG
Feb 14 — Feb 211
Sat 2/14
Sat 2/21
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Cleveland to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Cleveland to South America

Keep the following information in mind while searching for Cleveland to South America flight deals. Data was last updated January 15, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$292
(Kiwi.com)

One-way from

$169
(Avianca Connect)

Popular in

July

Cheapest in

February

Average price

$995
Provider with most accurate pricing for Cleveland Hopkins Intl-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Sao Paulo (SAO) flights.
Search Deals
From Cleveland Hopkins Intl to South America
Search Deals
One-way flight from Cleveland Hopkins Intl to South America
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($38 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Find flight deals from Cleveland to South America

Cheapest flights from Cleveland to South America
Explore the most affordable flight options available from Cleveland to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/217:10 pm
CLE
-
CTG
1 stop18h 00m
Multiple Airlines
Wed 2/252:21 pm
CTG
-
CLE
1 stop23h 42m
Multiple Airlines
Deal found 1/14$292
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/277:04 pm
CLE
-
CTG
1 stop18h 06m
Multiple Airlines
Fri 3/62:21 pm
CTG
-
CLE
1 stop11h 21m
Multiple Airlines
Deal found 1/13$304
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:04 pm
CLE
-
CTG
1 stop18h 06m
Multiple Airlines
Thu 3/121:21 pm
CTG
-
CLE
1 stop11h 21m
Multiple Airlines
Deal found 1/13$310
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/156:26 pm
CLE
-
CTG
1 stop18h 53m
Multiple Airlines
Tue 3/171:24 pm
CTG
-
CLE
1 stop9h 04m
Multiple Airlines
Deal found 1/14$316
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/94:38 pm
CLE
-
CTG
1 stop20h 41m
Multiple Airlines
Tue 4/141:24 pm
CTG
-
CLE
1 stop26h 16m
Multiple Airlines
Deal found 1/14$330
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/287:04 pm
CLE
-
CTG
1 stop18h 06m
Multiple Airlines
Sat 3/72:21 pm
CTG
-
CLE
2 stops19h 19m
Multiple Airlines
Deal found 1/13$336
This Avianca Connect deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:26 pm
CLE
-
MDE
1 stop28h 14m
Multiple Airlines
Tue 3/3110:20 am
MDE
-
CLE
1 stop29h 51m
Multiple Airlines
Deal found 1/15$365
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1110:30 am
CLE
-
MDE
2 stops27h 43m
Multiple Airlines
Wed 2/183:15 pm
MDE
-
CLE
1 stop23h 12m
Multiple Airlines
Deal found 1/14$369
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/146:29 pm
CLE
-
BOG
1 stop18h 18m
Multiple Airlines
Sat 2/211:45 pm
BOG
-
CLE
1 stop18h 01m
Multiple Airlines
Deal found 1/13$379
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/117:02 pm
CLE
-
MDE
1 stop19h 11m
Multiple Airlines
Sun 2/156:25 am
MDE
-
CLE
2 stops17h 00m
Multiple Airlines
Deal found 1/13$394
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/277:04 pm
CLE
-
MDE
1 stop19h 09m
Multiple Airlines
Fri 3/63:15 pm
MDE
-
CLE
1 stop10h 27m
Multiple Airlines
Deal found 1/13$398
This Mytrip deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/56:10 pm
CLE
-
LIM
2 stops56h 05m
Multiple Airlines
Wed 2/1111:33 pm
LIM
-
CLE
1 stop18h 36m
Multiple Airlines
Deal found 1/12$398

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cleveland to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from Cleveland to South America that are best for you.

Fly from

Cleveland

Fly to

South America

Route

Depart

Return

Price

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Sat 2/21

7:10 pm-1:10 pm

1 stop18h 00m

Cartagena Rafael Nunez

Wed 2/25

2:21 pm-2:03 pm

1 stop23h 42m

$292

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Fri 2/27

7:04 pm-1:10 pm

1 stop18h 06m

Cartagena Rafael Nunez

Fri 3/6

2:21 pm-1:42 am

1 stop11h 21m

$304

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Mon 3/9

7:04 pm-12:10 pm

1 stop18h 06m

Cartagena Rafael Nunez

Thu 3/12

1:24 pm-1:42 am

1 stop11h 18m

$315

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Sun 3/15

6:26 pm-12:19 pm

1 stop18h 53m

Cartagena Rafael Nunez

Tue 3/17

1:24 pm-11:28 pm

1 stop9h 04m

$316

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Thu 4/9

4:38 pm-12:19 pm

1 stop20h 41m

Cartagena Rafael Nunez

Tue 4/14

1:24 pm-4:40 pm

1 stop26h 16m

$330

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Sat 2/28

7:04 pm-1:10 pm

1 stop18h 06m

Cartagena Rafael Nunez

Sat 3/7

2:21 pm-9:40 am

2 stops19h 19m

$336

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Wed 3/25

6:26 pm-9:40 pm

1 stop28h 14m

Medellín Jose Maria Cordova Intl

Tue 3/31

10:20 am-5:11 pm

1 stop29h 51m

$365

ClevelandLima

CLE - LIM

CLELIM

Cleveland Hopkins Intl

Thu 2/5

6:10 pm-2:15 am

2 stops56h 05m

Lima J Chavez Intl

Wed 2/11

11:33 pm-6:09 pm

1 stop18h 36m

$398

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Wed 2/11

7:02 pm-2:13 pm

1 stop19h 11m

Medellín Jose Maria Cordova Intl

Wed 2/18

3:15 pm-2:27 pm

1 stop23h 12m

$401

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Tue 2/10

7:02 pm-1:55 pm

2 stops18h 53m

Medellín Jose Maria Cordova Intl

Tue 2/17

2:50 pm-6:09 pm

2 stops27h 19m

$405

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/14

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Cleveland to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Cleveland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cleveland to South America

What is the cheapest month to book a flight from Cleveland to South America?

Currently, February is the cheapest month in which you can book a flight from Cleveland to South America (average of $200). Flying from Cleveland to South America in December is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated January 15, 2026.
See what other customers who have flown with Delta, Copa Airlines, and LATAM Airlines from Cleveland to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,048 reviews

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,048 reviews
Delta
7.9
Good
8,048 reviews

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.6
Good
1,559 reviews
Delta
7.9
Good
8,048 reviews

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,904 reviews
Delta
7.9
Good
8,048 reviews

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,163 reviews
Delta
7.9
Good
8,048 reviews

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,130 reviews
Delta
7.9
Good
8,048 reviews

Crew

8.5

Entertainment

7.8

Overall

7.9

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Cleveland to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Cleveland to South America?

    Cleveland Hopkins Intl (CLE) is the airport you will fly out of if you book a flight from Cleveland to South America. It is only a 10.1 mi journey to Hopkins Intl (CLE) from Cleveland’s city center.

  • How long is the flight from Cleveland to South America?

    A quick flight from Cleveland to South America can take about 10h 25m. Spirit Airlines provides one of the quickest options available for as low as $448. The distance from Cleveland to South America is about 2579 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Cleveland to South America one-way?

    One-way options have recently been found by users for as low as $244 on Copa Airlines. Other airlines that offer cheap prices include Delta from $245 and American Airlines from $350 one-way.

  • What are the most popular routes from Cleveland to South America?

    The most popular route from Cleveland to South America is Cleveland Hopkins Intl - Lima J Chavez Intl. You may also consider Cleveland Hopkins Intl - Buenos Aires Ministro Pistarini or Cleveland Hopkins Intl - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from Cleveland to South America that include hotel bookings?

    Yes. In addition to deals on Cleveland to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cleveland to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cleveland to South America.

  • Can I find deals for business class flights from Cleveland to South America?

    Yes. Cheapflights offers flight deals from Cleveland to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cleveland to South America?

    Currently, February is the cheapest month in which you can book a flight from Cleveland to South America (average of $200). Flying from Cleveland to South America in December is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Cleveland to South America

See prices for flight routes from nearby airports that may be better suited for you.
Detroit to Orlando flights
Detroit to Fort Lauderdale flights
Detroit to Miami flights
Cleveland to Orlando flights
Detroit to Cancún flights
Cincinnati to Orlando flights
Detroit to Las Vegas flights
Cleveland to Fort Lauderdale flights
Detroit to Sky Harbor Intl flights
Cleveland to Fort Myers flights
Detroit to Tampa flights
Detroit to Dallas/Fort Worth flights
Cleveland to Las Vegas flights
Cincinnati to Las Vegas flights
Detroit to Fort Myers flights
Cincinnati to Fort Lauderdale flights
Cleveland to Tampa flights
Detroit to Los Angeles flights
Cincinnati to Tampa flights
Cincinnati to Fort Myers flights
Detroit to West Palm Beach flights
Cincinnati to John F Kennedy Intl flights
Akron to Orlando flights
Detroit to Denver flights
Cleveland to Sky Harbor Intl flights
Detroit to John F Kennedy Intl flights
Detroit to Sarasota flights
Pittsburgh to Orlando flights
Cincinnati to Sky Harbor Intl flights
Cincinnati to LaGuardia flights
Detroit to LaGuardia flights
Columbus to Las Vegas flights
Cincinnati to Newark flights
Pittsburgh to Fort Lauderdale flights
Pittsburgh to Tampa flights
Cleveland to John F Kennedy Intl flights
Cincinnati to Denver flights
Cleveland to Denver flights
Detroit to Newark flights
Pittsburgh to Las Vegas flights
Cleveland to Cancún flights
Detroit to Luis Munoz Marin Intl flights
Cleveland to Atlanta flights
Columbus to Orlando flights
Cleveland to LaGuardia flights
Cleveland to Miami flights
Columbus to John F Kennedy Intl flights
Columbus to Fort Lauderdale flights
Detroit to San Francisco flights
Cleveland to Dallas/Fort Worth flights

Top 5 airlines flying from Cleveland to South America

Discover the top 5 airlines that operate flights from Cleveland to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$413Average$898FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$462Average$746FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$469Average$837FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$498Average$858FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$536Average$788FlexibilityNo cancel feeOn-time70%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.