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South America

$126+ Cheap flights from Midway (MDW) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — BOG
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from Midway to South America

Keep the following information in mind while searching for Midway to South America flight deals. Data was last updated July 30, 2025.

Round-trip from

$325
(Delta)

One-way from

$126
(Delta)

Popular in

December

Cheapest in

March

Average price

$995
From Chicago Midway to South America
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One-way flight from Chicago Midway to South America
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Highest demand for flights based on searches. 9% potential increase in price ($98 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Midway to South America

Cheapest flights from Midway to South America
Explore the most affordable flight options available from Midway to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/156:00 amMDW - BOG
1 stop7h 40mDelta
Mon 9/291:35 amBOG - MDW
2 stops10h 53mDelta
Deal found 7/29$325
This Aviatur deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aviatur is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/912:48 pmMDW - BOG
2 stops22h 07mLATAM Airlines
Wed 10/1510:15 amBOG - MDW
2 stops11h 59mLATAM Airlines
Deal found 7/28$335
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:00 amMDW - CTG
1 stop7h 14mDelta
Mon 11/104:35 amCTG - MDW
2 stops12h 48mDelta
Deal found 7/30$403
This KAYAK deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:00 amMDW - CTG
1 stop7h 14mLATAM Airlines
Tue 11/113:06 pmCTG - MDW
1 stop7h 38mLATAM Airlines
Deal found 7/28$410
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/106:23 pmMDW - UIO
2 stops48h 36mDelta
Wed 10/159:11 amUIO - MDW
2 stops13h 03mDelta
Deal found 7/30$443
This Trip.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:00 amMDW - MDE
2 stops11h 27mMultiple Airlines
Sun 11/303:48 pmMDE - MDW
2 stops45h 07mMultiple Airlines
Deal found 7/27$454
This CheapOair deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/85:25 pmMDW - UIO
2 stops25h 40mLATAM Airlines
Tue 10/1411:20 pmUIO - MDW
1 stop10h 31mLATAM Airlines
Deal found 7/27$457
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/126:30 pmMDW - LIM
1 stop10h 30mDelta
Mon 9/2211:20 pmLIM - MDW
1 stop10h 20mDelta
Deal found 7/27$478
This LATAM Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/226:00 amMDW - LIM
1 stop15h 10mLATAM Airlines
Sat 9/2712:15 pmLIM - MDW
1 stop21h 25mLATAM Airlines
Deal found 7/28$485
This CheapOair deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/910:31 amMDW - MDE
2 stops21h 19mLATAM Airlines
Tue 10/2811:10 amMDE - MDW
2 stops22h 30mLATAM Airlines
Deal found 7/29$504
This Trip.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:25 pmMDW - CTG
1 stop19h 21mMultiple Airlines
Tue 11/189:27 amCTG - MDW
2 stops25h 24mMultiple Airlines
Deal found 7/28$539
This FlightHub deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/274:25 pmMDW - GIG
1 stop15h 50mLATAM Airlines
Tue 9/26:15 amGIG - MDW
2 stops17h 11mLATAM Airlines
Deal found 7/30$550

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to South America that are best for you.

Fly from

Midway

Fly to

South America

Route

Depart

Return

Price

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

Mon 9/15

6:00 am-1:40 pm

1 stop7h 40m

Bogotá El Dorado

Mon 9/29

1:35 am-12:28 pm

2 stops10h 53m

$325

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

Thu 10/9

12:48 pm-10:55 am

2 stops22h 07m

Bogotá El Dorado

Wed 10/15

10:15 am-10:14 pm

2 stops11h 59m

$335

ChicagoCartagena

MDW - CTG

MDWCTG

Chicago Midway

Fri 9/26

6:15 pm-1:16 pm

2 stops19h 01m

Cartagena Rafael Nunez

Tue 9/30

5:01 am-5:35 pm

2 stops12h 34m

$407

ChicagoQuito

MDW - UIO

MDWUIO

Chicago Midway

Fri 10/10

6:23 pm-6:59 pm

2 stops48h 36m

Quito Mariscal Sucr

Wed 10/15

9:11 am-10:14 pm

2 stops13h 03m

$443

ChicagoQuito

MDW - UIO

MDWUIO

Chicago Midway

Wed 10/8

5:25 pm-7:05 pm

2 stops25h 40m

Quito Mariscal Sucr

Tue 10/14

11:20 pm-9:51 am

1 stop10h 31m

$457

ChicagoLima

MDW - LIM

MDWLIM

Chicago Midway

Fri 9/12

6:30 pm-5:00 am

1 stop10h 30m

Lima J Chavez Intl

Mon 9/22

11:20 pm-9:40 am

1 stop10h 20m

$478

ChicagoLima

MDW - LIM

MDWLIM

Chicago Midway

Mon 9/22

6:00 am-9:10 pm

1 stop15h 10m

Lima J Chavez Intl

Sat 9/27

12:15 pm-9:40 am

1 stop21h 25m

$485

ChicagoMedellín

MDW - MDE

MDWMDE

Chicago Midway

Tue 9/16

6:00 am-7:25 pm

2 stops13h 25m

Medellín Jose Maria Cordova Intl

Sun 9/21

2:00 pm-7:23 am

1 stop17h 23m

$488

ChicagoCartagena

MDW - CTG

MDWCTG

Chicago Midway

Tue 10/21

10:35 am-9:43 am

2 stops23h 08m

Cartagena Rafael Nunez

Sun 10/26

4:35 am-10:14 pm

2 stops17h 39m

$493

ChicagoMedellín

MDW - MDE

MDWMDE

Chicago Midway

Tue 9/9

10:31 am-7:50 am

2 stops21h 19m

Medellín Jose Maria Cordova Intl

Tue 10/28

11:10 am-9:40 am

2 stops22h 30m

$504

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 53 results
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Best time to book a flight from Midway to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to South America

What is the cheapest time of day to fly from MDW to SA?

Find hourly flight availability from Midway to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Chicago Midway Airport to South America as you normally would.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated July 30, 2025.
Read reviews from past customers who have flown Delta, LATAM Airlines, and Aeromexico from Chicago Midway Airport to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,822 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Aeromexico
7.5
Good
1,721 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Midway to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Chicago Midway Airport to South America one-way?

    The cheapest airlines for a one-way flight from Chicago Midway Airport to South America are Delta ($126), LATAM Airlines ($145), and Aeromexico ($410).

  • What are the most popular routes from Chicago Midway Airport to South America?

    While some choose either Chicago Midway - Bogotá El Dorado or Chicago Midway - Buenos Aires Ministro Pistarini, Chicago Midway - Lima J Chavez Intl is the most popular route from Chicago Midway Airport to South America.

  • Can I find deals for flights from Midway to South America that include hotel bookings?

    Yes. In addition to deals on Midway to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to South America.

  • Can I find deals for business class flights from Midway to South America?

    Yes. Cheapflights offers flight deals from Midway to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to South America?

    Currently, May is the cheapest month in which you can book a flight from Chicago Midway Airport to South America (average of $359). Flying from Chicago Midway Airport to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Midway to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Midway to South America

Discover the top 2 airlines that operate flights from Midway to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$348Average$650FlexibilityNo cancel feeOn-time81%
DeltaCheapest$374Average$649FlexibilityNo cancel feeOn-timeN/A

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