South America

$116+ Cheap flights from Midway (MDW) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — BOG
Jun 17 — Jun 241
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Cheap flight deals from Midway to South America

Keep the following information in mind while searching for Midway to South America flight deals. Data was last updated June 12, 2025.

Round-trip from

$316
(Justfly.com)

One-way from

$116
(Delta)

Popular in

October

Cheapest in

March

Average price

$1,097
From Chicago Midway to South America
One-way flight from Chicago Midway to South America
Highest demand for flights based on searches. 13% potential increase in price ($144 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($31 potential savings vs. average RT price).
Average for round-trip flights in June 2025

Find flight deals from Midway to South America

Cheapest flights from Midway to South America
Explore the most affordable flight options available from Midway to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Justfly.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/206:00 amMDW - BOG
1 stop7h 40mLATAM Airlines
Wed 10/12:55 pmBOG - MDW
1 stop18h 56mLATAM Airlines
Deal found 6/12$316
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:00 amMDW - BOG
1 stop7h 30mDelta
Tue 11/113:50 pmBOG - MDW
1 stop19h 01mDelta
Deal found 6/11$321
This Justfly.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:00 amMDW - CTG
1 stop6h 46mLATAM Airlines
Tue 11/113:06 pmCTG - MDW
1 stop7h 38mLATAM Airlines
Deal found 6/12$332
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/46:20 pmMDW - CTG
2 stops18h 53mDelta
Thu 8/212:05 pmCTG - MDW
1 stop7h 44mDelta
Deal found 6/9$346
This LATAM Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:00 amMDW - MDE
2 stops15h 10mLATAM Airlines
Wed 11/127:47 pmMDE - MDW
2 stops21h 36mLATAM Airlines
Deal found 6/11$433
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/44:25 pmMDW - UIO
1 stop26h 40mDelta
Sun 10/1211:20 pmUIO - MDW
1 stop22h 24mDelta
Deal found 6/10$456
This SmartFares deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:00 amMDW - UIO
1 stop13h 05mLATAM Airlines
Wed 11/511:50 pmUIO - MDW
1 stop22h 54mLATAM Airlines
Deal found 6/11$477
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/35:25 pmMDW - MDE
2 stops49h 04mDelta
Fri 11/148:02 amMDE - MDW
2 stops26h 49mDelta
Deal found 6/11$493
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/410:31 amMDW - CTG
2 stops25h 39mMultiple Airlines
Thu 7/101:28 pmCTG - MDW
2 stops20h 13mMultiple Airlines
Deal found 6/10$503
This Justfly.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/225:25 pmMDW - LIM
2 stops13h 00mLATAM Airlines
Mon 9/298:15 amLIM - MDW
2 stops13h 29mLATAM Airlines
Deal found 6/10$516
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/246:42 pmMDW - GIG
1 stop13h 33mDelta
Tue 8/269:00 pmGIG - MDW
1 stop14h 16mDelta
Deal found 6/11$552
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:00 amMDW - LIM
2 stops15h 45mDelta
Tue 11/1112:15 pmLIM - MDW
1 stop10h 29mDelta
Deal found 6/9$559

Cheapflights Fare Finder

Customize your flight search to find flights from Midway to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to South America that are best for you.

Fly from

Midway

Fly to

South America

Route

Depart

Return

Price

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

Wed 8/13

10:11 am-7:15 pm

1 stop9h 04m

Bogotá El Dorado

Wed 8/27

10:15 am-9:49 pm

2 stops11h 34m

$320

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

Wed 8/13

10:11 am-7:15 pm

1 stop9h 04m

Bogotá El Dorado

Mon 8/18

1:35 am-12:28 pm

2 stops10h 53m

$325

ChicagoCartagena

MDW - CTG

MDWCTG

Chicago Midway

Mon 8/4

6:20 pm-1:13 pm

2 stops18h 53m

Cartagena Rafael Nunez

Thu 8/21

2:05 pm-9:49 pm

1 stop7h 44m

$346

ChicagoCartagena

MDW - CTG

MDWCTG

Chicago Midway

Mon 8/4

6:47 pm-1:13 pm

1 stop18h 26m

Cartagena Rafael Nunez

Thu 8/21

2:05 pm-9:49 pm

1 stop7h 44m

$379

ChicagoQuito

MDW - UIO

MDWUIO

Chicago Midway

Sat 10/4

4:25 pm-7:05 pm

1 stop26h 40m

Quito Mariscal Sucr

Sun 10/12

11:20 pm-9:44 pm

1 stop22h 24m

$456

ChicagoQuito

MDW - UIO

MDWUIO

Chicago Midway

Sat 10/25

6:00 am-7:05 pm

1 stop13h 05m

Quito Mariscal Sucr

Wed 11/5

11:50 pm-9:44 pm

1 stop22h 54m

$477

ChicagoCartagena

MDW - CTG

MDWCTG

Chicago Midway

Fri 7/4

10:31 am-12:10 pm

2 stops25h 39m

Cartagena Rafael Nunez

Thu 7/10

1:28 pm-9:41 am

2 stops20h 13m

$503

ChicagoLima

MDW - LIM

MDWLIM

Chicago Midway

Sun 8/31

4:25 pm-6:25 am

2 stops14h 00m

Lima J Chavez Intl

Sat 9/27

8:15 am-9:44 pm

2 stops13h 29m

$516

ChicagoMedellín

MDW - MDE

MDWMDE

Chicago Midway

Tue 8/5

6:00 am-10:00 pm

2 stops16h 00m

Medellín Jose Maria Cordova Intl

Sun 8/10

6:01 am-9:42 pm

2 stops15h 41m

$531

ChicagoRio de Janeiro

MDW - GIG

MDWGIG

Chicago Midway

Sun 8/24

6:42 pm-10:15 am

1 stop13h 33m

Rio de Janeiro–Galeão Intl

Tue 8/26

9:00 pm-9:16 am

1 stop14h 16m

$552

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 56 results
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Best time to book a flight from Midway to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to South America

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated June 12, 2025.
8.0
Very good

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Midway to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the most popular routes from Chicago Midway Airport to South America?

  • Can I find deals for flights from Midway to South America that include hotel bookings?

    Yes. In addition to deals on Midway to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to South America.

  • Can I find deals for business class flights from Midway to South America?

    Yes. Cheapflights offers flight deals from Midway to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to South America?

    Currently, May is the cheapest month in which you can book a flight from Chicago Midway Airport to South America (average of $359). Flying from Chicago Midway Airport to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Midway to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Midway to South America

Discover the top airline that operate flights from Midway to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$467Average$618FlexibilityNo cancel feeOn-time81%

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