HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South America

$109+ Cheap flights from Charlotte (CLT) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — BOG
dic 10 — dic 171
mer 12/10
mer 12/17
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charlotte to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Charlotte to South America

Keep the following information in mind while searching for Charlotte to South America flight deals. Data was last updated novembre 10, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$259
(Expedia)

One-way from

$109
(Priceline)

Popular in

November

Cheapest in

April

Average price

$1,627
Provider with most accurate pricing for Charlotte Douglas-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Sao Paulo (SAO) flights.
Search Deals
From Charlotte Douglas to South America
Search Deals
One-way flight from Charlotte Douglas to South America
Search Deals
Highest demand for flights based on searches. 28% potential increase in price ($430 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($58 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Charlotte to South America

Cheapest flights from Charlotte to South America
Explore the most affordable flight options available from Charlotte to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on novembre 10, 2025.

This Expedia deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 12/78:55 amCLT - MDE
1 stop16h 14mSpirit Airlines
sab 12/132:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 11/9$259
This CheapOair deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 12/87:00 amCLT - CTG
1 stop6h 10mSpirit Airlines
ven 12/122:15 pmCTG - CLT
1 stop9h 44mSpirit Airlines
Deal found 11/10$267
This Mytrip deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 12/128:55 amCLT - BOG
1 stop16h 17mSpirit Airlines
lun 12/153:05 pmBOG - CLT
1 stop8h 54mSpirit Airlines
Deal found 11/8$277
This Expedia deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 12/78:55 amCLT - MDE
1 stop16h 14mSpirit Airlines
ven 12/123:10 pmMDE - CLT
1 stop8h 49mSpirit Airlines
Deal found 11/8$283
This Orbitz deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 12/88:55 pmCLT - MDE
1 stop14h 00mSpirit Airlines
sab 12/132:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 11/10$292
This CheapOair deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 12/128:55 amCLT - MDE
1 stop16h 14mSpirit Airlines
sab 12/132:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 11/9$295
This KAYAK deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 11/257:30 amCLT - CTG
1 stop5h 55mSpirit Airlines
gio 12/42:15 pmCTG - CLT
1 stop9h 44mSpirit Airlines
Deal found 11/8$295
This Expedia deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 12/118:55 pmCLT - BOG
1 stop15h 57mSpirit Airlines
dom 12/142:17 amBOG - CLT
1 stop7h 22mSpirit Airlines
Deal found 11/8$297
This CheapOair deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 11/297:30 amCLT - MDE
1 stop17h 26mSpirit Airlines
ven 12/52:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 11/10$299
This Orbitz deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 11/277:30 amCLT - BOG
1 stop6h 40mSpirit Airlines
dom 12/72:17 amBOG - CLT
1 stop7h 22mSpirit Airlines
Deal found 11/10$300
This KAYAK deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 12/102:58 pmCLT - MDE
2 stops43h 57mSpirit Airlines
sab 12/132:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 11/10$300
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 11/245:59 pmCLT - CTG
1 stop19h 26mSpirit Airlines
sab 12/62:15 pmCTG - CLT
1 stop9h 44mSpirit Airlines
Deal found 11/8$300

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charlotte to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated novembre 10, 2025.
Use the filters below to find and compare flights from Charlotte to South America that are best for you.

Fly from

Charlotte

Fly to

South America

Route

Depart

Return

Price

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

lun 12/8

7:00 am-1:10 pm

1 stop6h 10m

Cartagena Rafael Nunez

lun 12/15

2:15 pm-11:59 pm

1 stop9h 44m

$267

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

lun 12/8

8:55 pm-10:55 am

1 stop14h 00m

Medellín Jose Maria Cordova Intl

sab 12/13

2:05 am-9:39 am

1 stop7h 34m

$292

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

ven 12/12

2:58 pm-1:09 am

1 stop10h 11m

Medellín Jose Maria Cordova Intl

sab 12/13

2:05 am-9:39 am

1 stop7h 34m

$303

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

ven 2/6

7:02 pm-2:15 pm

1 stop19h 13m

Medellín Jose Maria Cordova Intl

mer 2/11

3:15 pm-12:40 am

1 stop9h 25m

$309

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

gio 12/11

8:55 pm-1:10 pm

2 stops16h 15m

Cartagena Rafael Nunez

lun 12/15

2:15 pm-11:59 pm

1 stop9h 44m

$314

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

dom 11/23

5:59 pm-1:25 pm

1 stop19h 26m

Cartagena Rafael Nunez

sab 12/6

2:15 pm-11:59 pm

1 stop9h 44m

$340

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

dom 11/23

2:57 pm-1:25 pm

2 stops22h 28m

Cartagena Rafael Nunez

gio 12/4

2:15 pm-11:59 pm

1 stop9h 44m

$341

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

lun 12/1

5:59 pm-12:56 am

1 stop6h 57m

Medellín Jose Maria Cordova Intl

mer 12/17

3:10 pm-11:59 pm

1 stop8h 49m

$347

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

gio 2/5

7:00 am-1:13 pm

1 stop6h 13m

Cartagena Rafael Nunez

lun 2/9

2:21 pm-12:40 am

1 stop10h 19m

$347

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

mer 12/10

8:55 am-9:40 pm

1 stop12h 45m

Medellín Jose Maria Cordova Intl

mar 12/16

1:00 pm-11:59 pm

1 stop10h 59m

$350

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/9

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Charlotte to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Charlotte with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charlotte to South America

What is the cheapest month to book a flight from Charlotte to South America?

Currently, October is the cheapest month in which you can book a flight from Charlotte to South America (average of $96). Flying from Charlotte to South America in June is currently the most expensive (average of $423). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLT to SA?

Find hourly flight availability from Charlotte to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated novembre 10, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 7% on flights from Charlotte to South America by exploring options for tickets at noon.

What is the cheapest day to fly from Charlotte to South America?

Use this chart to determine the cheapest time to fly round-trip from Charlotte to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Charlotte to South America flight should consider departing on Sunday evenings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated novembre 10, 2025.
Read reviews from past customers who have flown Delta, LATAM Airlines, and GOL from Charlotte to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,872 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
GOL
7.3
Good
1,127 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,045 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,135 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charlotte to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charlotte to South America?

    For a flight from Charlotte to South America, you will be flying from Douglas. Charlotte Douglas (CLT) is just 5.7 mi from the center of the city.

  • How long is the flight from Charlotte to South America?

    A quick flight from Charlotte to South America can take about 6h 10m. Spirit Airlines provides one of the quickest options available for as low as $267. Charlotte and South America are separated by a distance of 1745 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Charlotte to South America?

    Most travelers choose Charlotte Douglas - Medellín Jose Maria Cordova Intl, Charlotte Douglas - Lima J Chavez Intl or Charlotte Douglas - Bogotá El Dorado when deciding on the best route from Charlotte to South America.

  • Can I find deals for flights from Charlotte to South America that include hotel bookings?

    Yes. In addition to deals on Charlotte to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charlotte to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charlotte to South America.

  • Can I find deals for business class flights from Charlotte to South America?

    Yes. Cheapflights offers flight deals from Charlotte to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charlotte to South America?

    Currently, October is the cheapest month in which you can book a flight from Charlotte to South America (average of $96). Flying from Charlotte to South America in June is currently the most expensive (average of $423). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charlotte to South America

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to John F Kennedy Intl flights
Raleigh to John F Kennedy Intl flights
Raleigh to LaGuardia flights
Charlotte to LaGuardia flights
Raleigh to Miami flights
Raleigh to Newark flights
Raleigh to Las Vegas flights
Charlotte to Newark flights
Raleigh to Orlando flights
Charlotte to Denver flights
Raleigh to Denver flights
Raleigh to Luis Munoz Marin Intl flights
Raleigh to O'Hare Intl flights
Charlotte to Dallas/Fort Worth flights
Charlotte to Las Vegas flights
Raleigh to Los Angeles flights
Raleigh to Cancún flights
Raleigh to Hobby flights
Charlotte to O'Hare Intl flights
Raleigh to Dallas/Fort Worth flights
Charlotte to Cancún flights
Charlotte to Hobby flights
Charlotte to Orlando flights
Raleigh to George Bush Intcntl flights
Charlotte to Sky Harbor Intl flights
Charlotte to Fort Lauderdale flights
Raleigh to Fort Lauderdale flights
Raleigh to Sky Harbor Intl flights
Charlotte to Boston flights
Raleigh to Boston flights
Raleigh to San Francisco flights
Charlotte to Los Angeles flights
Charlotte to George Bush Intcntl flights
Charlotte to Miami flights
Raleigh to Seattle flights
Raleigh to Tampa flights
Charlotte to Dulles Intl flights
Greensboro to LaGuardia flights
Greensboro to Newark flights
Raleigh to New Orleans flights
Charlotte to Luis Munoz Marin Intl flights
Raleigh to Heathrow flights
Raleigh to Atlanta flights
Greensboro to John F Kennedy Intl flights
Raleigh to Midway flights
Charlotte to Heathrow flights
Norfolk to John F Kennedy Intl flights
Raleigh to Austin flights
Charlotte to Seattle flights
Asheville to LaGuardia flights

Top 6 airlines flying from Charlotte to South America

Discover the top 6 airlines that operate flights from Charlotte to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated novembre 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$251Average$433FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$394Average$764FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$441Average$886FlexibilityNo cancel feeOn-time71%
DeltaCheapest$449Average$959FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$482Average$787FlexibilityNo cancel feeOn-time81%
GOLCheapest$667Average$878FlexibilityNo cancel feeOn-time74%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.