$91+ Cheap flights from Charlotte (CLT) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — BOG
Mar 29 — Apr 51
1 adult, Economy
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Find cheap flights from Charlotte to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charlotte to South America
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Cheapest flights from Charlotte to South AmericaExplore the most affordable flight options available from Charlotte to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 27, 2026.
Explore the most affordable flight options available from Charlotte to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 27, 2026.
This Travelocity deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/211:20 pm
CLT
- MDE
1 stop12h 01m
Spirit Airlines
Mon 4/62:17 pm
MDE
- CLT
1 stop17h 04m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$243
This Orbitz deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
CLT
- CTG
1 stop7h 06m
Spirit Airlines
Wed 4/151:11 pm
CTG
- CLT
1 stop8h 22m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$246
This Cheapflightsfares deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:55 am
CLT
- MDE
1 stop16h 21m
Spirit Airlines
Sun 4/262:06 pm
MDE
- CLT
1 stop7h 27m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$249
This Orbitz deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
CLT
- MDE
1 stop8h 22m
Spirit Airlines
Fri 4/172:06 pm
MDE
- CLT
1 stop7h 27m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$250
This FlightHub deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:00 am
CLT
- MDE
1 stop8h 08m
Spirit Airlines
Fri 5/151:11 am
MDE
- CLT
1 stop8h 06m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$256
This Expedia deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
CLT
- CTG
1 stop7h 06m
Spirit Airlines
Sat 4/181:11 pm
CTG
- CLT
1 stop8h 22m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:20 pm
CLT
- MDE
1 stop12h 01m
Spirit Airlines
Thu 5/142:06 pm
MDE
- CLT
1 stop7h 27m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 am
CLT
- MDE
1 stop8h 22m
Spirit Airlines
Fri 4/171:11 am
MDE
- CLT
1 stop8h 06m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$259
This Cheapflightsfares deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/271:20 pm
CLT
- MDE
1 stop12h 01m
Spirit Airlines
Fri 4/172:06 pm
MDE
- CLT
1 stop7h 27m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/81:20 pm
CLT
- MDE
1 stop12h 01m
Spirit Airlines
Sun 4/191:11 am
MDE
- CLT
1 stop8h 06m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/99:00 pm
CLT
- MDE
1 stop17h 22m
Spirit Airlines
Fri 4/172:06 pm
MDE
- CLT
1 stop7h 27m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$265
This Mytrip deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:55 am
CLT
- BOG
1 stop8h 15m
Spirit Airlines
Wed 3/112:05 pm
BOG
- CLT
1 stop17h 16m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$266
Best flights from Charlotte to South AmericaDiscover carefully curated flight deals from Charlotte to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 27, 2026.
Discover carefully curated flight deals from Charlotte to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 27, 2026.
This Expedia deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:55 am
CLT
- CTG
1 stop7h 15m
Spirit Airlines
Wed 3/181:14 pm
CTG
- CLT
1 stop10h 24m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/293:15 pm
CLT
- CLO
1 stop23h 04m
Multiple Airlines
Tue 5/262:24 pm
CLO
- CLT
1 stop16h 52m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$337
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:43 pm
CLT
- MDE
2 stops26h 27m
United Airlines
Sun 5/109:45 am
MDE
- CLT
1 stop10h 54m
United Airlines
Deal found 2/25![United Airlines logo]()
$461
This Delta deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:05 pm
CLT
- BOG
2 stops9h 30m
Delta
Thu 6/48:40 am
BOG
- CLT
2 stops12h 19m
Delta
Deal found 2/24![Delta logo]()
$500
This Copa Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:40 pm
CLT
- CLO
2 stops16h 26m
Copa Airlines
Tue 5/2612:06 pm
CLO
- CLT
2 stops20h 39m
Copa Airlines
Deal found 2/23![Copa Airlines logo]()
$511
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1810:39 pm
CLT
- CTG
1 stop16h 34m
American Airlines
Tue 6/233:13 pm
CTG
- CLT
1 stop16h 21m
American Airlines
Deal found 2/26![American Airlines logo]()
$559
This Cheapflightsfares deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/129:00 pm
CLT
- CLO
1 stop17h 19m
Spirit Airlines
Sun 4/192:24 pm
CLO
- CLT
1 stop18h 53m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$299
This Spirit deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:55 am
CLT
- BOG
1 stop8h 15m
Spirit Airlines
Mon 3/162:10 pm
BOG
- CLT
2 stops23h 50m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$305
This Mytrip deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/249:00 pm
CLT
- CLO
2 stops26h 03m
Multiple Airlines
Tue 3/3111:37 am
CLO
- CLT
2 stops12h 01m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$339
This SmartFares deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:44 pm
CLT
- SDU
2 stops19h 06m
GOL
Sun 5/1710:45 am
SDU
- CLT
2 stops35h 40m
GOL
Deal found 2/23![GOL logo]()
$690
This Cheapflightsfares deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/279:00 pm
CLT
- CLO
1 stop17h 19m
Spirit Airlines
Fri 4/32:24 pm
CLO
- CLT
1 stop9h 14m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$324
This Mytrip deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:55 am
CLT
- CTG
2 stops18h 10m
Multiple Airlines
Wed 3/1810:52 am
CTG
- CLT
3 stops20h 29m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$378
This CheapOair deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/289:54 pm
CLT
- MDE
1 stop16h 14m
Spirit Airlines
Wed 5/61:55 pm
MDE
- CLT
1 stop17h 14m
Spirit Airlines
Deal found 2/27![Spirit Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:45 am
CLT
- MDE
1 stop15h 25m
United Airlines
Tue 5/199:45 am
MDE
- CLT
2 stops24h 00m
United Airlines
Deal found 2/23![United Airlines logo]()
$469
This Avianca Connect deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:55 am
CLT
- CTG
2 stops13h 20m
Multiple Airlines
Mon 5/115:35 am
CTG
- CLT
2 stops15h 58m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$388
This FlightHub deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/269:00 pm
CLT
- CTG
1 stop16h 06m
Spirit Airlines
Tue 3/311:14 pm
CTG
- CLT
1 stop10h 24m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$346
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:35 am
CLT
- BOG
2 stops15h 35m
Delta
Sun 5/3111:00 am
BOG
- CLT
2 stops20h 56m
Delta
Deal found 2/26![Delta logo]()
$510
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:45 am
CLT
- MDE
1 stop15h 25m
United Airlines
Thu 5/149:45 am
MDE
- CLT
2 stops24h 00m
United Airlines
Deal found 2/23![United Airlines logo]()
$469
This Copa Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:44 pm
CLT
- CLO
2 stops19h 26m
Copa Airlines
Mon 7/206:16 pm
CLO
- CLT
2 stops14h 29m
Copa Airlines
Deal found 2/25![Copa Airlines logo]()
$521
This Mytrip deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/199:00 pm
CLT
- CLO
1 stop17h 19m
Multiple Airlines
Sun 3/2210:25 pm
CLO
- CLT
3 stops32h 56m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$412
This Delta deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:05 am
CLT
- BOG
2 stops12h 45m
Delta
Mon 6/111:00 am
BOG
- CLT
2 stops20h 56m
Delta
Deal found 2/24![Delta logo]()
$510
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:05 am
CLT
- MDE
2 stops14h 05m
United Airlines
Sun 5/179:45 am
MDE
- CLT
2 stops37h 45m
United Airlines
Deal found 2/23![United Airlines logo]()
$479
This Copa Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
CLT
- CTG
2 stops18h 00m
Copa Airlines
Mon 5/113:05 pm
CTG
- CLT
2 stops17h 48m
Copa Airlines
Deal found 2/24![Copa Airlines logo]()
$531
This Spirit deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/99:00 pm
CLT
- MDE
1 stop17h 22m
Spirit Airlines
Sun 4/122:17 pm
MDE
- CLT
1 stop17h 04m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:59 am
CLT
- BOG
2 stops11h 51m
Delta
Mon 6/111:00 am
BOG
- CLT
2 stops11h 53m
Delta
Deal found 2/26![Delta logo]()
$510
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/74:45 pm
CLT
- MDE
1 stop29h 25m
United Airlines
Fri 5/229:45 am
MDE
- CLT
1 stop11h 14m
United Airlines
Deal found 2/26![United Airlines logo]()
$483
This Copa Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:00 am
CLT
- CTG
2 stops12h 54m
Copa Airlines
Mon 7/279:24 am
CTG
- CLT
2 stops23h 21m
Copa Airlines
Deal found 2/24![Copa Airlines logo]()
$550
This Avianca Connect deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:12 am
CLT
- UIO
2 stops15h 03m
Multiple Airlines
Tue 5/53:30 am
UIO
- CLT
2 stops19h 17m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$455
This CheapOair deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1811:12 am
CLT
- CTG
2 stops25h 53m
Spirit Airlines
Wed 5/271:11 pm
CTG
- CLT
2 stops20h 03m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$379
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/229:41 am
CLT
- BOG
1 stop10h 34m
Delta
Mon 5/259:00 am
BOG
- CLT
1 stop10h 14m
Delta
Deal found 2/23![Delta logo]()
$515
Last-minute flights from Charlotte to South AmericaDiscover last-minute flight deals from Charlotte to South America. Data last updated February 27, 2026 and is based on user searches.
Discover last-minute flight deals from Charlotte to South America. Data last updated February 27, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:55 am
CLT
- BOG
1 stop8h 15m
Spirit Airlines
Wed 3/112:05 pm
BOG
- CLT
1 stop17h 16m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$266
This CheapOair deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:55 am
CLT
- BOG
1 stop8h 15m
Spirit Airlines
Tue 3/312:10 pm
BOG
- CLT
1 stop9h 28m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:55 am
CLT
- MDE
1 stop8h 18m
Multiple Airlines
Tue 3/171:17 am
MDE
- CLT
1 stop12h 00m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$271
This CheapOair deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/171:20 pm
CLT
- MDE
1 stop12h 01m
Spirit Airlines
Tue 3/241:52 pm
MDE
- CLT
2 stops9h 46m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$272
This CheapOair deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/209:00 pm
CLT
- MDE
1 stop17h 22m
Spirit Airlines
Sun 3/221:17 am
MDE
- CLT
1 stop18h 00m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$275
This Travelocity deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/211:20 pm
CLT
- MDE
1 stop12h 01m
Spirit Airlines
Mon 4/62:17 pm
MDE
- CLT
1 stop17h 04m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$243
This Cheapflightsfares deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/219:00 pm
CLT
- MDE
1 stop17h 22m
Spirit Airlines
Tue 3/312:17 pm
MDE
- CLT
1 stop17h 04m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$265
This Cheapflightsfares deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/226:00 am
CLT
- MDE
1 stop8h 22m
Spirit Airlines
Mon 3/301:17 am
MDE
- CLT
1 stop18h 00m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$266
This Orbitz deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:00 am
CLT
- BOG
1 stop8h 11m
Spirit Airlines
Tue 3/312:10 pm
BOG
- CLT
1 stop9h 28m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$275
This Cheapflightsfares deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/271:20 pm
CLT
- MDE
1 stop12h 01m
Spirit Airlines
Fri 4/172:06 pm
MDE
- CLT
1 stop7h 27m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:20 pm
CLT
- MDE
1 stop12h 01m
Spirit Airlines
Thu 5/142:06 pm
MDE
- CLT
1 stop7h 27m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:20 pm
CLT
- MDE
1 stop12h 01m
Spirit Airlines
Mon 5/181:11 am
MDE
- CLT
1 stop8h 06m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$278
One-way flights from Charlotte to South AmericaSearch for one-way flight options from Charlotte to South America. Find affordable one-way fares based on user searches. Data last updated February 27, 2026.
Search for one-way flight options from Charlotte to South America. Find affordable one-way fares based on user searches. Data last updated February 27, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:00 am
CLT
- MDE
1 stop8h 22m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$91
This Cheapflightsfares deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/81:20 pm
CLT
- MDE
1 stop12h 01m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:00 am
CLT
- BOG
1 stop8h 11m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$103
This Cheapflightsfares deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/146:00 am
CLT
- MDE
1 stop8h 22m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$110
This Mytrip deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:00 am
CLT
- MDE
1 stop8h 08m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$115
This Cheapflightsfares deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:00 am
CLT
- CLO
1 stop8h 19m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
CLT
- MDE
1 stop8h 08m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$116
This Mytrip deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/251:20 pm
CLT
- BOG
2 stops17h 20m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$118
This FlightHub deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
CLT
- MDE
1 stop8h 08m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:55 am
CLT
- MDE
1 stop16h 21m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$120
This CheapOair deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:00 am
CLT
- CLO
1 stop8h 19m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$121
This Super.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/219:00 pm
CLT
- MDE
1 stop17h 22m
Spirit Airlines
Deal found 2/27![Spirit Airlines logo]()
$122
Find flight deals from Charlotte to South America
Keep the following information in mind while searching for Charlotte to South America flight deals. Data was last updated February 27, 2026.
Round-trip from | $243 (Travelocity) |
|---|---|
One-way from | $91 (Cheapflightsfares) |
Popular in | January |
Cheapest in | February |
Average price | $354 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charlotte to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
Use the filters below to find and compare flights from Charlotte to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
CharlotteCartagena
CLT - CTG
CLTCTG
Charlotte Douglas
Tue 3/10
5:55 am-12:10 pm
1 stop7h 15m
Cartagena Rafael Nunez
Wed 3/18
1:14 pm-12:38 am
1 stop10h 24m
$297
CharlotteCali
CLT - CLO
CLTCLO
Charlotte Douglas
Sun 4/12
9:00 pm-1:19 pm
1 stop17h 19m
Cali Alfonso B. Aragon Intl
Sun 4/19
2:24 pm-10:17 am
1 stop18h 53m
$299
CharlotteBogotá
CLT - BOG
CLTBOG
Charlotte Douglas
Mon 3/9
5:55 am-1:10 pm
1 stop8h 15m
Bogotá El Dorado
Mon 3/16
2:10 pm-3:00 pm
2 stops23h 50m
$305
CharlotteCali
CLT - CLO
CLTCLO
Charlotte Douglas
Fri 3/27
9:00 pm-1:19 pm
1 stop17h 19m
Cali Alfonso B. Aragon Intl
Fri 4/3
2:24 pm-12:38 am
1 stop9h 14m
$324
CharlotteMedellín
CLT - MDE
CLTMDE
Charlotte Douglas
Tue 4/28
9:54 pm-1:08 pm
1 stop16h 14m
Medellín Jose Maria Cordova Intl
Wed 5/6
1:55 pm-8:09 am
1 stop17h 14m
$325
CharlotteCali
CLT - CLO
CLTCLO
Charlotte Douglas
Wed 4/29
3:15 pm-1:19 pm
1 stop23h 04m
Cali Alfonso B. Aragon Intl
Tue 5/26
2:24 pm-8:16 am
1 stop16h 52m
$337
CharlotteCali
CLT - CLO
CLTCLO
Charlotte Douglas
Tue 3/24
9:00 pm-10:03 pm
2 stops26h 03m
Cali Alfonso B. Aragon Intl
Tue 3/31
11:37 am-12:38 am
2 stops12h 01m
$339
CharlotteCartagena
CLT - CTG
CLTCTG
Charlotte Douglas
Thu 3/26
9:00 pm-12:06 pm
1 stop16h 06m
Cartagena Rafael Nunez
Tue 3/31
1:14 pm-12:38 am
1 stop10h 24m
$346
CharlotteMedellín
CLT - MDE
CLTMDE
Charlotte Douglas
Thu 4/9
9:00 pm-1:22 pm
1 stop17h 22m
Medellín Jose Maria Cordova Intl
Sun 4/12
2:17 pm-8:21 am
1 stop17h 04m
$372
CharlotteCartagena
CLT - CTG
CLTCTG
Charlotte Douglas
Tue 3/10
5:55 am-11:05 pm
2 stops18h 10m
Cartagena Rafael Nunez
Wed 3/18
10:52 am-8:21 am
3 stops20h 29m
$378
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Charlotte to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Charlotte with our price prediction graph.
CLT-MDE
CLT-BOG
CLT-CTG
CLT-CLO
CLT-SDU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charlotte to South America
CLT-0SA
CLT-MDE
CLT-BOG
CLT-CTG
CLT-CLO
What is the cheapest month to book a flight from Charlotte to South America?
Currently, October is the cheapest month in which you can book a flight from Charlotte to South America (average of $96). Flying from Charlotte to South America in June is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated February 27, 2026.
Read reviews from past customers who have flown Delta, LATAM Airlines, and GOL from Charlotte to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Food
7.2
Overall
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Food
7.2
Overall
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Food
7.2
Overall
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Food
7.2
Overall
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Food
7.2
Overall
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Food
7.2
Overall
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Charlotte to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Charlotte to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charlotte to South America by cabin class
Find flights from Charlotte to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charlotte and South America flights
Browse other Charlotte and South America flight options. Last updated on February 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Charlotte to South America flights
Consider these flights traveling from Charlotte to South America.
Top 6 airlines flying from Charlotte to South America
Discover the top 6 airlines that operate flights from Charlotte to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$149 | Average$413 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$424 | Average$508 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$435 | Average$904 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$452 | Average$1,017 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$487 | Average$760 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$667 | Average$990 | FlexibilityNo cancel fee | On-time74% |