South America

$114+ Cheap flights from Charlotte (CLT) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — BOG
nov 16 — nov 231
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Cheap flight deals from Charlotte to South America

Keep the following information in mind while searching for Charlotte to South America flight deals. Data was last updated outubro 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$279
(Cheapflightsfares)

One-way from

$114
(CheapOair)

Popular in

December

Cheapest in

April
Provider with most accurate pricing for Charlotte Douglas-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for Charlotte Douglas-Sao Paulo (SAO) flights.
From Charlotte Douglas to South America
One-way flight from Charlotte Douglas to South America
Highest demand for flights based on searches. 4% potential increase in price ($49 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($34 potential savings vs. average RT price).

Find flight deals from Charlotte to South America

Cheapest flights from Charlotte to South America
Explore the most affordable flight options available from Charlotte to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on outubro 17, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 12/53:15 pmCLT - MDE
1 stop10h 05mSpirit Airlines
dom 12/72:15 amMDE - CLT
1 stop7h 24mSpirit Airlines
Deal found 10/17$279
This Expedia deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 11/1210:07 amCLT - MDE
1 stop14h 50mSpirit Airlines
sáb 11/151:52 amMDE - CLT
1 stop7h 10mSpirit Airlines
Deal found 10/15$304
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 11/310:07 amCLT - CTG
1 stop27h 08mSpirit Airlines
sex 11/72:20 pmCTG - CLT
1 stop18h 42mSpirit Airlines
Deal found 10/17$311
This CheapOair deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 12/43:15 pmCLT - MDE
1 stop10h 05mSpirit Airlines
ter 12/92:15 amMDE - CLT
1 stop12h 05mSpirit Airlines
Deal found 10/16$319
This Cheapflightsfares deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 11/86:44 pmCLT - MDE
1 stop6h 13mSpirit Airlines
sex 11/141:52 amMDE - CLT
1 stop7h 10mSpirit Airlines
Deal found 10/15$327
This Cheapflightsfares deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 11/510:07 amCLT - MDE
1 stop14h 50mSpirit Airlines
sex 11/71:52 amMDE - CLT
1 stop7h 10mSpirit Airlines
Deal found 10/15$328
This CheapOair deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 11/86:44 pmCLT - MDE
1 stop6h 13mSpirit Airlines
seg 11/101:52 amMDE - CLT
1 stop7h 10mSpirit Airlines
Deal found 10/17$329
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 12/15:59 pmCLT - BOG
1 stop20h 11mSpirit Airlines
seg 12/83:05 pmBOG - CLT
1 stop23h 15mSpirit Airlines
Deal found 10/16$338
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 11/86:44 pmCLT - CTG
1 stop18h 31mSpirit Airlines
qui 11/132:20 pmCTG - CLT
1 stop18h 42mSpirit Airlines
Deal found 10/17$338
This CheapOair deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 12/53:15 pmCLT - MDE
1 stop10h 05mSpirit Airlines
dom 12/711:50 amMDE - CLT
1 stop7h 22mSpirit Airlines
Deal found 10/16$339
This Avianca Connect deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 11/69:38 pmCLT - GYE
2 stops20h 52mMultiple Airlines
seg 11/106:55 pmGYE - CLT
2 stops18h 05mMultiple Airlines
Deal found 10/15$344
This Cheapflightsfares deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 11/247:30 amCLT - BOG
1 stop6h 40mSpirit Airlines
sáb 12/61:59 amBOG - CLT
1 stop7h 40mSpirit Airlines
Deal found 10/16$345

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charlotte to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated outubro 17, 2025.
Use the filters below to find and compare flights from Charlotte to South America that are best for you.

Fly from

Charlotte

Fly to

South America

Route

Depart

Return

Price

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

sex 12/5

3:15 pm-1:20 am

1 stop10h 05m

Medellín Jose Maria Cordova Intl

dom 12/7

2:15 am-9:39 am

1 stop7h 24m

$279

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

sáb 11/8

6:44 pm-12:57 am

1 stop6h 13m

Medellín Jose Maria Cordova Intl

sex 11/14

1:52 am-9:02 am

1 stop7h 10m

$327

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

sex 11/7

9:38 pm-2:30 pm

2 stops16h 52m

Guayaquil Jose Joaquin de Olmedo

dom 11/9

6:55 pm-7:47 am

2 stops12h 52m

$344

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

qua 1/28

10:11 pm-1:55 pm

1 stop15h 44m

Medellín Jose Maria Cordova Intl

ter 2/3

12:09 pm-9:06 pm

1 stop8h 57m

$349

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

sex 11/7

6:44 pm-9:40 pm

1 stop26h 56m

Medellín Jose Maria Cordova Intl

seg 11/10

1:00 pm-9:02 am

1 stop20h 02m

$350

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

seg 2/2

5:06 pm-9:40 pm

1 stop28h 34m

Medellín Jose Maria Cordova Intl

seg 3/2

1:00 pm-9:27 am

1 stop20h 27m

$350

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

sex 1/23

10:11 pm-11:03 am

1 stop12h 52m

Medellín Jose Maria Cordova Intl

sáb 2/7

1:51 am-9:27 am

1 stop7h 36m

$358

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

sex 10/31

1:49 pm-5:20 am

1 stop16h 31m

Guayaquil Jose Joaquin de Olmedo

ter 11/4

7:05 pm-1:00 pm

1 stop17h 55m

$363

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

qua 1/21

5:06 pm-12:56 am

1 stop7h 50m

Medellín Jose Maria Cordova Intl

sáb 1/24

12:09 pm-9:06 pm

1 stop8h 57m

$363

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

qui 12/4

7:00 am-1:20 pm

1 stop6h 20m

Cartagena Rafael Nunez

dom 12/7

2:25 pm-10:09 pm

1 stop7h 44m

$367

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/16

Showing 1-10 of 60 results
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Best time to book a flight from Charlotte to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Charlotte with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charlotte to South America

What is the cheapest month to book a flight from Charlotte to South America?

Currently, October is the cheapest month in which you can book a flight from Charlotte to South America (average of $96). Flying from Charlotte to South America in June is currently the most expensive (average of $423). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLT to SA?

Find hourly flight availability from Charlotte to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated outubro 17, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 3% on flights from Charlotte to South America by exploring options for tickets at noon.

What is the cheapest day to fly from Charlotte to South America?

Use this chart to determine the cheapest time to fly round-trip from Charlotte to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Charlotte to South America flight should consider departing on Sunday evenings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated outubro 17, 2025.
Read reviews from past customers who have flown Delta, LATAM Airlines, and GOL from Charlotte to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.5

Comfort

7.9

Food

7.3

Overall

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Crew

8.5

Comfort

7.9

Food

7.3

Overall

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Crew

8.5

Comfort

7.9

Food

7.3

Overall

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Crew

8.5

Comfort

7.9

Food

7.3

Overall

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Crew

8.5

Comfort

7.9

Food

7.3

Overall

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Crew

8.5

Comfort

7.9

Food

7.3

Overall

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Charlotte to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Charlotte to South America?

    For a flight from Charlotte to South America, you will be flying from Douglas. Charlotte Douglas (CLT) is just 5.7 mi from the center of the city.

  • How long is the flight from Charlotte to South America?

    A quick flight from Charlotte to South America can take about 10h 05m. Spirit Airlines provides one of the quickest options available for as low as $279. Charlotte and South America are separated by a distance of 2037 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Charlotte to South America?

  • Can I find deals for flights from Charlotte to South America that include hotel bookings?

    Yes. In addition to deals on Charlotte to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charlotte to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charlotte to South America.

  • Can I find deals for business class flights from Charlotte to South America?

    Yes. Cheapflights offers flight deals from Charlotte to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charlotte to South America?

    Currently, October is the cheapest month in which you can book a flight from Charlotte to South America (average of $96). Flying from Charlotte to South America in June is currently the most expensive (average of $423). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Charlotte to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Charlotte to South America

Discover the top 6 airlines that operate flights from Charlotte to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated outubro 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$247Average$432FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$394Average$718FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$444Average$891FlexibilityNo cancel feeOn-time71%
DeltaCheapest$452Average$900FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$482Average$818FlexibilityNo cancel feeOn-time81%
GOLCheapest$667Average$888FlexibilityNo cancel feeOn-time74%

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