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South America

$109+ Cheap flights from Charlotte (CLT) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/1. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — BOG
Dec 24 — Dec 311
Wed 12/24
Wed 12/31
1 adult, Economy
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Cheap flight deals from Charlotte to South America

Keep the following information in mind while searching for Charlotte to South America flight deals. Data was last updated November 24, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$209
(Expedia)

One-way from

$109
(Priceline)

Popular in

November

Cheapest in

April

Average price

$1,627
Provider with most accurate pricing for Charlotte Douglas-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Charlotte Douglas-Sao Paulo (SAO) flights.
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From Charlotte Douglas to South America
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One-way flight from Charlotte Douglas to South America
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Highest demand for flights based on searches. 28% potential increase in price ($430 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($58 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Charlotte to South America

Cheapest flights from Charlotte to South America
Explore the most affordable flight options available from Charlotte to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 24, 2025.

This Priceline deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:00 amCLT - CTG
1 stop6h 10mSpirit Airlines
Thu 12/112:15 pmCTG - CLT
1 stop9h 44mSpirit Airlines
Deal found 11/23$242
This Spirit Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/82:58 pmCLT - MDE
1 stop10h 11mSpirit Airlines
Thu 12/112:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 11/23$280
This Expedia deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/132:57 pmCLT - MDE
1 stop10h 12mSpirit Airlines
Sun 12/212:25 amMDE - CLT
1 stop7h 14mSpirit Airlines
Deal found 11/22$291
This CheapOair deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:55 amCLT - MDE
1 stop16h 14mSpirit Airlines
Sun 12/142:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 11/22$296
This CheapOair deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:55 pmCLT - MDE
1 stop14h 00mSpirit Airlines
Sun 12/212:25 amMDE - CLT
1 stop7h 14mSpirit Airlines
Deal found 11/22$307
This Mytrip deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/88:55 pmCLT - CTG
2 stops16h 15mMultiple Airlines
Thu 12/119:10 amCTG - CLT
2 stops14h 49mMultiple Airlines
Deal found 11/23$311
This eDestinos deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/62:57 pmCLT - MDE
1 stop10h 12mSpirit Airlines
Sun 12/142:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 11/22$318
This KAYAK deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/132:57 pmCLT - MDE
1 stop10h 12mSpirit Airlines
Sat 12/202:25 amMDE - CLT
1 stop18h 08mSpirit Airlines
Deal found 11/21$319
This Travelocity deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1012:59 pmCLT - BOG
2 stops23h 53mSpirit Airlines
Thu 12/113:05 pmBOG - CLT
1 stop8h 54mSpirit Airlines
Deal found 11/23$323
This KAYAK deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:00 amCLT - CTG
1 stop6h 10mSpirit Airlines
Mon 12/292:15 pmCTG - CLT
1 stop19h 24mSpirit Airlines
Deal found 11/22$327
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/73:42 pmCLT - GYE
1 stop13h 38mMultiple Airlines
Tue 12/1612:49 amGYE - CLT
1 stop13h 14mMultiple Airlines
Deal found 11/23$332
This KAYAK deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/92:58 pmCLT - GYE
1 stop8h 45mSpirit Airlines
Tue 12/1612:49 amGYE - CLT
1 stop13h 14mSpirit Airlines
Deal found 11/23$335

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charlotte to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
Use the filters below to find and compare flights from Charlotte to South America that are best for you.

Fly from

Charlotte

Fly to

South America

Route

Depart

Return

Price

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Mon 12/8

7:00 am-1:10 pm

1 stop6h 10m

Cartagena Rafael Nunez

Thu 12/11

2:15 pm-11:59 pm

1 stop9h 44m

$244

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Wed 1/21

7:00 am-1:15 pm

1 stop6h 15m

Cartagena Rafael Nunez

Mon 2/2

2:21 pm-12:40 am

1 stop10h 19m

$267

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Sun 1/25

7:00 am-12:21 am

1 stop17h 21m

Guayaquil Jose Joaquin de Olmedo

Tue 1/27

1:26 am-10:58 am

1 stop9h 32m

$286

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Thu 1/29

6:56 pm-2:15 pm

1 stop19h 19m

Medellín Jose Maria Cordova Intl

Mon 2/2

3:15 pm-12:40 am

1 stop9h 25m

$290

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Sun 1/18

7:00 am-1:15 pm

1 stop6h 15m

Cartagena Rafael Nunez

Sun 1/25

2:21 pm-12:40 am

1 stop10h 19m

$290

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 2/4

7:00 am-12:21 am

1 stop17h 21m

Guayaquil Jose Joaquin de Olmedo

Wed 2/18

12:59 am-6:02 pm

1 stop17h 03m

$291

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Wed 1/21

7:00 am-2:15 pm

1 stop7h 15m

Medellín Jose Maria Cordova Intl

Sat 1/24

3:15 pm-8:26 am

1 stop17h 11m

$294

CharlotteCali

CLT - CLO

CLTCLO

Charlotte Douglas

Mon 1/26

7:00 am-2:15 pm

1 stop7h 15m

Cali Alfonso B. Aragon Intl

Thu 1/29

3:22 pm-8:26 am

1 stop17h 04m

$295

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 2/5

1:24 pm-12:21 am

1 stop10h 57m

Guayaquil Jose Joaquin de Olmedo

Tue 2/17

12:59 am-12:40 am

1 stop23h 41m

$297

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Thu 1/29

6:56 pm-1:55 pm

2 stops18h 59m

Medellín Jose Maria Cordova Intl

Tue 2/3

3:15 pm-12:40 am

1 stop9h 25m

$308

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/22

Showing 1-10 of 60 results
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Best time to book a flight from Charlotte to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Charlotte with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charlotte to South America

What is the cheapest month to book a flight from Charlotte to South America?

Currently, October is the cheapest month in which you can book a flight from Charlotte to South America (average of $96). Flying from Charlotte to South America in June is currently the most expensive (average of $423). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLT to SA?

Find hourly flight availability from Charlotte to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 24, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 6% on flights from Charlotte to South America by exploring options for tickets in the evening.

What is the cheapest day to fly from Charlotte to South America?

Use this chart to determine the cheapest time to fly round-trip from Charlotte to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Charlotte to South America flight should consider departing on Sunday mornings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated November 24, 2025.
Read reviews from past customers who have flown Delta, LATAM Airlines, and GOL from Charlotte to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,887 reviews
Delta
7.9
Good
7,998 reviews

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
GOL
7.3
Good
1,128 reviews
Delta
7.9
Good
7,998 reviews

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
7,998 reviews

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,158 reviews
Delta
7.9
Good
7,998 reviews

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charlotte to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charlotte to South America?

    For a flight from Charlotte to South America, you will be flying from Douglas. Charlotte Douglas (CLT) is just 5.7 mi from the center of the city.

  • How long is the flight from Charlotte to South America?

    A quick flight from Charlotte to South America can take about 6h 10m. Spirit Airlines provides one of the quickest options available for as low as $244. Charlotte and South America are separated by a distance of 1745 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Charlotte to South America?

    Most travelers choose Charlotte Douglas - Medellín Jose Maria Cordova Intl, Charlotte Douglas - Lima J Chavez Intl or Charlotte Douglas - Bogotá El Dorado when deciding on the best route from Charlotte to South America.

  • Can I find deals for flights from Charlotte to South America that include hotel bookings?

    Yes. In addition to deals on Charlotte to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charlotte to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charlotte to South America.

  • Can I find deals for business class flights from Charlotte to South America?

    Yes. Cheapflights offers flight deals from Charlotte to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charlotte to South America?

    Currently, October is the cheapest month in which you can book a flight from Charlotte to South America (average of $96). Flying from Charlotte to South America in June is currently the most expensive (average of $423). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charlotte to South America

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Top 6 airlines flying from Charlotte to South America

Discover the top 6 airlines that operate flights from Charlotte to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$279Average$455FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$394Average$764FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$441Average$918FlexibilityNo cancel feeOn-time71%
DeltaCheapest$449Average$959FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$482Average$821FlexibilityNo cancel feeOn-time81%
GOLCheapest$667Average$872FlexibilityNo cancel feeOn-time74%

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