$144+ Cheap flights from Charlotte (CLT) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/16. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — BOG
Jun 26 — Jul 31
Round-trip
1 adult, Economy
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Find cheap flights from Charlotte to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charlotte to South America
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Cheapest flights from Charlotte to South AmericaExplore the most affordable flight options available from Charlotte to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 27, 2026.
Explore the most affordable flight options available from Charlotte to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 27, 2026.
This JetBlue deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/309:00 am
CLT
- MDE
1 stop6h 45m
JetBlue
Thu 9/32:25 pm
MDE
- CLT
1 stop7h 35m
JetBlue
Deal found 5/26![JetBlue logo]()
$372
This JetBlue deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/79:00 am
CLT
- MDE
1 stop6h 45m
JetBlue
Wed 9/161:30 pm
MDE
- CLT
1 stop8h 30m
JetBlue
Deal found 5/26![JetBlue logo]()
$373
This JetBlue deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/289:00 am
CLT
- MDE
1 stop6h 45m
JetBlue
Thu 9/32:25 pm
MDE
- CLT
1 stop7h 35m
JetBlue
Deal found 5/26![JetBlue logo]()
$394
This SmartFares deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:50 am
CLT
- CTG
1 stop5h 45m
JetBlue
Sat 7/2512:35 pm
CTG
- CLT
1 stop9h 30m
JetBlue
Deal found 5/24![JetBlue logo]()
$396
This JetBlue deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/79:00 am
CLT
- MDE
1 stop6h 45m
JetBlue
Fri 9/111:30 pm
MDE
- CLT
1 stop8h 30m
JetBlue
Deal found 5/26![JetBlue logo]()
$400
This KAYAK deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:50 am
CLT
- CTG
1 stop5h 45m
JetBlue
Thu 9/1012:35 pm
CTG
- CLT
1 stop9h 25m
JetBlue
Deal found 5/24![JetBlue logo]()
$409
This Ovago deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:50 am
CLT
- CTG
1 stop5h 45m
JetBlue
Wed 8/1212:35 pm
CTG
- CLT
1 stop9h 25m
JetBlue
Deal found 5/26![JetBlue logo]()
$410
This JetBlue deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:50 am
CLT
- CTG
1 stop5h 45m
JetBlue
Thu 9/312:35 pm
CTG
- CLT
1 stop7h 34m
JetBlue
Deal found 5/26![JetBlue logo]()
$411
This Cheapflightsfares deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:50 am
CLT
- MDE
1 stop8h 55m
JetBlue
Fri 9/42:25 pm
MDE
- CLT
1 stop7h 35m
JetBlue
Deal found 5/26![JetBlue logo]()
$422
This Flighttix deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:50 am
CLT
- CTG
1 stop5h 45m
JetBlue
Wed 7/2212:35 pm
CTG
- CLT
1 stop7h 34m
JetBlue
Deal found 5/23![JetBlue logo]()
$422
This Ovago deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/309:00 am
CLT
- MDE
1 stop6h 45m
JetBlue
Fri 9/42:25 pm
MDE
- CLT
1 stop7h 35m
JetBlue
Deal found 5/26![JetBlue logo]()
$426
This JetBlue deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/69:00 am
CLT
- MDE
1 stop6h 45m
JetBlue
Tue 9/151:30 pm
MDE
- CLT
1 stop8h 30m
JetBlue
Deal found 5/26![JetBlue logo]()
$427
Best flights from Charlotte to South AmericaDiscover carefully curated flight deals from Charlotte to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 27, 2026.
Discover carefully curated flight deals from Charlotte to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 27, 2026.
This JetBlue deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:50 am
CLT
- CTG
1 stop5h 45m
JetBlue
Thu 9/312:35 pm
CTG
- CLT
1 stop7h 34m
JetBlue
Deal found 5/24![JetBlue logo]()
$411
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:45 am
CLT
- MDE
2 stops15h 25m
United Airlines
Wed 9/169:45 am
MDE
- CLT
2 stops23h 39m
United Airlines
Deal found 5/26![United Airlines logo]()
$484
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:45 am
CLT
- BOG
2 stops14h 25m
Delta
Tue 8/185:00 am
BOG
- CLT
2 stops17h 57m
Delta
Deal found 5/26![Delta logo]()
$540
This Copa Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:30 am
CLT
- LIM
2 stops15h 50m
Copa Airlines
Fri 10/302:35 am
LIM
- CLT
2 stops31h 09m
Copa Airlines
Deal found 5/24![Copa Airlines logo]()
$614
This GOL deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/215:50 pm
CLT
- GRU
2 stops28h 15m
GOL
Sun 6/2810:40 pm
GRU
- CLT
2 stops37h 14m
GOL
Deal found 5/22![GOL logo]()
$798
This Kiwi.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:58 pm
CLT
- UIO
2 stops41h 34m
Multiple Airlines
Tue 8/189:00 am
UIO
- CLT
1 stop31h 14m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$827
This JetBlue deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:50 am
CLT
- GYE
1 stop9h 32m
JetBlue
Tue 8/111:25 pm
GYE
- CLT
1 stop8h 35m
JetBlue
Deal found 5/23![JetBlue logo]()
$478
This LATAM Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:45 am
CLT
- GRU
1 stop15h 55m
LATAM Airlines
Sun 11/159:15 pm
GRU
- CLT
1 stop14h 54m
LATAM Airlines
Deal found 5/26![LATAM Airlines logo]()
$1,017
This JetBlue deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/89:00 am
CLT
- GYE
1 stop7h 20m
JetBlue
Fri 8/141:25 pm
GYE
- CLT
1 stop8h 35m
JetBlue
Deal found 5/23![JetBlue logo]()
$478
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:00 am
CLT
- MDE
2 stops16h 10m
United Airlines
Sun 8/309:45 am
MDE
- CLT
2 stops23h 23m
United Airlines
Deal found 5/24![United Airlines logo]()
$531
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:54 pm
CLT
- BOG
2 stops17h 11m
Delta
Mon 8/315:00 am
BOG
- CLT
2 stops17h 57m
Delta
Deal found 5/24![Delta logo]()
$545
This JetBlue deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:50 am
CLT
- GYE
1 stop9h 30m
JetBlue
Wed 9/21:25 pm
GYE
- CLT
1 stop8h 35m
JetBlue
Deal found 5/26![JetBlue logo]()
$486
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:05 am
CLT
- MDE
2 stops38h 05m
United Airlines
Thu 8/139:45 am
MDE
- CLT
2 stops23h 23m
United Airlines
Deal found 5/26![United Airlines logo]()
$545
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:30 am
CLT
- BOG
1 stop14h 45m
Delta
Sat 8/295:00 am
BOG
- CLT
2 stops17h 57m
Delta
Deal found 5/23![Delta logo]()
$555
This JetBlue deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:50 am
CLT
- GYE
1 stop9h 30m
JetBlue
Thu 9/31:25 pm
GYE
- CLT
1 stop8h 35m
JetBlue
Deal found 5/23![JetBlue logo]()
$486
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:00 am
CLT
- MDE
1 stop15h 10m
United Airlines
Tue 6/309:45 am
MDE
- CLT
2 stops27h 05m
United Airlines
Deal found 5/22![United Airlines logo]()
$553
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:30 am
CLT
- BOG
2 stops15h 40m
Delta
Mon 9/711:00 am
BOG
- CLT
2 stops20h 38m
Delta
Deal found 5/22![Delta logo]()
$560
This JetBlue deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:50 am
CLT
- CTG
1 stop5h 45m
JetBlue
Wed 8/512:35 pm
CTG
- CLT
1 stop9h 30m
JetBlue
Deal found 5/26![JetBlue logo]()
$487
This United Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:40 am
CLT
- BOG
1 stop11h 55m
United Airlines
Thu 3/111:30 am
BOG
- CLT
1 stop9h 22m
United Airlines
Deal found 5/23![United Airlines logo]()
$555
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:30 pm
CLT
- BOG
2 stops19h 35m
Delta
Sat 9/52:55 pm
BOG
- CLT
1 stop18h 13m
Delta
Deal found 5/22![Delta logo]()
$575
This GOL deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/225:15 am
CLT
- GIG
2 stops16h 45m
GOL
Sun 6/2810:25 pm
GIG
- CLT
2 stops36h 29m
GOL
Deal found 5/22![GOL logo]()
$801
This JetBlue deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/89:00 am
CLT
- MDE
1 stop6h 45m
JetBlue
Tue 9/151:30 pm
MDE
- CLT
1 stop8h 30m
JetBlue
Deal found 5/26![JetBlue logo]()
$499
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3111:45 am
CLT
- MDE
1 stop10h 25m
United Airlines
Fri 9/49:45 am
MDE
- CLT
2 stops23h 23m
United Airlines
Deal found 5/24![United Airlines logo]()
$557
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/410:07 am
CLT
- BOG
1 stop10h 08m
Delta
Fri 9/115:00 am
BOG
- CLT
2 stops17h 57m
Delta
Deal found 5/22![Delta logo]()
$575
This GOL deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:15 am
CLT
- GRU
2 stops16h 50m
GOL
Thu 7/2310:40 pm
GRU
- CLT
2 stops37h 14m
GOL
Deal found 5/25![GOL logo]()
$820
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:05 am
CLT
- MDE
2 stops38h 05m
United Airlines
Sat 9/129:45 am
MDE
- CLT
2 stops23h 39m
United Airlines
Deal found 5/24![United Airlines logo]()
$569
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:30 pm
CLT
- BOG
1 stop21h 10m
Delta
Sat 9/128:40 am
BOG
- CLT
2 stops14h 17m
Delta
Deal found 5/26![Delta logo]()
$576
This JetBlue deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:00 am
CLT
- GYE
1 stop7h 20m
JetBlue
Sat 8/151:25 pm
GYE
- CLT
1 stop8h 35m
JetBlue
Deal found 5/23![JetBlue logo]()
$564
This GOL deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:50 pm
CLT
- GRU
2 stops25h 20m
GOL
Fri 10/169:55 pm
GRU
- CLT
2 stops35h 30m
GOL
Deal found 5/26![GOL logo]()
$827
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:00 am
CLT
- BOG
1 stop16h 00m
United Airlines
Mon 9/148:30 am
BOG
- CLT
2 stops24h 54m
United Airlines
Deal found 5/26![United Airlines logo]()
$570
Last-minute flights from Charlotte to South AmericaDiscover last-minute flight deals from Charlotte to South America. Data last updated May 27, 2026 and is based on user searches.
Discover last-minute flight deals from Charlotte to South America. Data last updated May 27, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/710:39 pm
CLT
- CTG
1 stop16h 34m
American Airlines
Wed 6/173:13 pm
CTG
- CLT
1 stop16h 21m
American Airlines
Deal found 5/24![American Airlines logo]()
$479
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1210:39 pm
CLT
- CTG
1 stop14h 56m
American Airlines
Tue 6/163:13 pm
CTG
- CLT
1 stop16h 21m
American Airlines
Deal found 5/23![American Airlines logo]()
$548
This oojo deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:50 pm
CLT
- GIG
2 stops26h 10m
GOL
Tue 6/2310:05 pm
GIG
- CLT
2 stops24h 26m
GOL
Deal found 5/24![GOL logo]()
$605
This United Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/163:50 pm
CLT
- BOG
1 stop13h 35m
United Airlines
Thu 7/237:20 am
BOG
- CLT
1 stop12h 02m
United Airlines
Deal found 5/23![United Airlines logo]()
$620
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:00 am
CLT
- MDE
1 stop15h 10m
United Airlines
Tue 6/309:45 am
MDE
- CLT
2 stops27h 05m
United Airlines
Deal found 5/22![United Airlines logo]()
$553
This United Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2012:50 pm
CLT
- MDE
2 stops33h 20m
United Airlines
Sat 9/59:45 am
MDE
- CLT
2 stops27h 33m
United Airlines
Deal found 5/23![United Airlines logo]()
$582
This American Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/204:44 pm
CLT
- MDE
1 stop8h 06m
American Airlines
Fri 7/1712:30 am
MDE
- CLT
1 stop8h 40m
American Airlines
Deal found 5/25![American Airlines logo]()
$612
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:59 am
CLT
- BOG
2 stops14h 11m
Delta
Tue 6/3011:00 am
BOG
- CLT
2 stops22h 13m
Delta
Deal found 5/24![Delta logo]()
$610
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2210:39 pm
CLT
- BOG
1 stop13h 41m
American Airlines
Tue 6/3012:21 pm
BOG
- CLT
1 stop19h 13m
American Airlines
Deal found 5/24![American Airlines logo]()
$621
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:50 pm
CLT
- BOG
1 stop16h 30m
American Airlines
Tue 6/3012:21 pm
BOG
- CLT
1 stop19h 13m
American Airlines
Deal found 5/24![American Airlines logo]()
$616
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:30 am
CLT
- BOG
1 stop14h 45m
Delta
Tue 7/75:15 pm
BOG
- CLT
2 stops17h 06m
Delta
Deal found 5/26![Delta logo]()
$605
This American Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/274:44 pm
CLT
- CTG
1 stop20h 51m
American Airlines
Mon 7/63:17 pm
CTG
- CLT
1 stop18h 37m
American Airlines
Deal found 5/26![American Airlines logo]()
$559
One-way flights from Charlotte to South AmericaSearch for one-way flight options from Charlotte to South America. Find affordable one-way fares based on user searches. Data last updated May 27, 2026.
Search for one-way flight options from Charlotte to South America. Find affordable one-way fares based on user searches. Data last updated May 27, 2026.
This SmartFares deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/169:00 am
CLT
- GYE
1 stop7h 20m
JetBlue
Deal found 5/26![JetBlue logo]()
$144
This Cheapflightsfares deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:50 am
CLT
- GYE
1 stop9h 30m
JetBlue
Deal found 5/26![JetBlue logo]()
$159
This Super.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:50 am
CLT
- CTG
1 stop5h 45m
JetBlue
Deal found 5/24![JetBlue logo]()
$169
This JetBlue deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:50 am
CLT
- CTG
1 stop5h 45m
JetBlue
Deal found 5/26![JetBlue logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:48 pm
CLT
- MDE
2 stops20h 57m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:48 pm
CLT
- BOG
2 stops17h 18m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:48 pm
CLT
- BOG
2 stops23h 38m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$208
This Ovago deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:50 am
CLT
- CTG
1 stop5h 45m
JetBlue
Deal found 5/24![JetBlue logo]()
$216
This JetBlue deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:50 am
CLT
- CTG
1 stop5h 45m
JetBlue
Deal found 5/24![JetBlue logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:48 pm
CLT
- CTG
3 stops45h 34m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:48 pm
CLT
- BOG
2 stops17h 18m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:48 pm
CLT
- BOG
2 stops17h 18m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$237
Find flight deals from Charlotte to South America
Keep the following information in mind while searching for Charlotte to South America flight deals. Data was last updated May 27, 2026.
Round-trip from | $372 (JetBlue) |
|---|---|
One-way from | $144 (SmartFares) |
Popular in | January |
Cheapest in | February |
Average price | $515 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charlotte to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 27, 2026.
Use the filters below to find and compare flights from Charlotte to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
CharlotteCartagena
CLT - CTG
CLTCTG
Charlotte Douglas
Sun 8/30
6:50 am-11:35 am
1 stop5h 45m
Cartagena Rafael Nunez
Thu 9/3
12:35 pm-9:09 pm
1 stop7h 34m
$411
CharlotteGuayaquil
CLT - GYE
CLTGYE
Charlotte Douglas
Sun 8/2
6:50 am-3:22 pm
1 stop9h 32m
Guayaquil Jose Joaquin de Olmedo
Tue 8/11
1:25 pm-11:00 pm
1 stop8h 35m
$478
CharlotteGuayaquil
CLT - GYE
CLTGYE
Charlotte Douglas
Sat 8/8
9:00 am-3:20 pm
1 stop7h 20m
Guayaquil Jose Joaquin de Olmedo
Fri 8/14
1:25 pm-11:00 pm
1 stop8h 35m
$478
CharlotteMedellín
CLT - MDE
CLTMDE
Charlotte Douglas
Tue 9/8
6:45 am-9:10 pm
2 stops15h 25m
Medellín Jose Maria Cordova Intl
Wed 9/16
9:45 am-10:24 am
2 stops23h 39m
$484
CharlotteGuayaquil
CLT - GYE
CLTGYE
Charlotte Douglas
Mon 8/31
6:50 am-3:20 pm
1 stop9h 30m
Guayaquil Jose Joaquin de Olmedo
Wed 9/2
1:25 pm-11:00 pm
1 stop8h 35m
$486
CharlotteGuayaquil
CLT - GYE
CLTGYE
Charlotte Douglas
Mon 8/31
6:50 am-3:20 pm
1 stop9h 30m
Guayaquil Jose Joaquin de Olmedo
Thu 9/3
1:25 pm-11:00 pm
1 stop8h 35m
$486
CharlotteCartagena
CLT - CTG
CLTCTG
Charlotte Douglas
Wed 7/22
6:50 am-11:35 am
1 stop5h 45m
Cartagena Rafael Nunez
Wed 8/5
12:35 pm-11:05 pm
1 stop9h 30m
$487
CharlotteMedellín
CLT - MDE
CLTMDE
Charlotte Douglas
Tue 9/8
9:00 am-2:45 pm
1 stop6h 45m
Medellín Jose Maria Cordova Intl
Tue 9/15
1:30 pm-11:00 pm
1 stop8h 30m
$499
CharlotteMedellín
CLT - MDE
CLTMDE
Charlotte Douglas
Fri 8/28
6:00 am-9:10 pm
2 stops16h 10m
Medellín Jose Maria Cordova Intl
Sun 8/30
9:45 am-10:08 am
2 stops23h 23m
$531
CharlotteBogotá
CLT - BOG
CLTBOG
Charlotte Douglas
Tue 8/11
6:45 am-8:10 pm
2 stops14h 25m
Bogotá El Dorado
Tue 8/18
5:00 am-11:57 pm
2 stops17h 57m
$540
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Charlotte to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Charlotte with our price prediction graph.
CLT-MDE
CLT-CTG
CLT-GYE
CLT-LIM
CLT-GIG
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charlotte to South America
CLT-0SA
CLT-MDE
CLT-CTG
CLT-GYE
CLT-LIM
What is the cheapest month to book a flight from Charlotte to South America?
Currently, February is the cheapest month in which you can book a flight from Charlotte to South America (average of $72). Flying from Charlotte to South America in December is currently the most expensive (average of $1,534). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Charlotte to South America?
To ensure you get the cheapest price possible for a flight from Charlotte to South America, you should look to book at least 63 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated May 27, 2026.
Read reviews from past customers who have flown Delta,LATAM Airlines, andGOL from Charlotte to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Spirit Airlines
Crew
8.5
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Charlotte to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Charlotte to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charlotte to South America by cabin class
Find flights from Charlotte to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charlotte and South America flights
Browse other Charlotte and South America flight options. Last updated on May 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Charlotte to South America flights
Consider these flights traveling from Charlotte to South America.
Top 5 airlines flying from Charlotte to South America
Discover the top 5 airlines that operate flights from Charlotte to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$238 | Average$423 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$435 | Average$1,012 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$483 | Average$1,062 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$502 | Average$730 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$646 | Average$950 | FlexibilityNo cancel fee | On-time74% |