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South America

$139+ Cheap flights from Charleston (CHS) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BOG
ene. 8 — ene. 151
jue. 1/8
jue. 1/15
1 adult, Economy
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Cheap flight deals from Charleston to South America

Cheapest flights from Charleston to South America
Explore the most affordable flight options available from Charleston to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 9, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/92:59 pmCHS - BOG
1 stop21h 53mMultiple Airlines
lun. 12/151:47 pmBOG - CHS
1 stop18h 50mMultiple Airlines
Deal found 12/8$519
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/129:49 pmCHS - BOG
1 stop16h 20mSpirit Airlines
dom. 12/143:05 pmBOG - CHS
1 stop29h 49mSpirit Airlines
Deal found 12/8$554
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/129:49 pmCHS - BOG
2 stops18h 21mMultiple Airlines
dom. 12/141:47 pmBOG - CHS
1 stop19h 10mMultiple Airlines
Deal found 12/8$560
This Expedia deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/103:30 pmCHS - CTG
1 stop22h 47mMultiple Airlines
dom. 12/142:15 pmCTG - CHS
1 stop6h 39mMultiple Airlines
Deal found 12/7$607
This Kiwi.com deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/2110:18 pmCHS - GYE
1 stop25h 35mMultiple Airlines
mié. 12/2412:49 amGYE - CHS
2 stops32h 08mMultiple Airlines
Deal found 12/6$659
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/302:59 pmCHS - MDE
1 stop19h 56mMultiple Airlines
mar. 1/65:05 pmMDE - CHS
2 stops48h 31mMultiple Airlines
Deal found 12/8$692
This KAYAK deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/2610:18 pmCHS - GYE
1 stop25h 35mSpirit Airlines
jue. 1/112:49 amGYE - CHS
1 stop20h 34mSpirit Airlines
Deal found 12/8$701
This KAYAK deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/129:49 pmCHS - LIM
1 stop24h 46mSpirit Airlines
dom. 12/1411:37 pmLIM - CHS
1 stop21h 17mSpirit Airlines
Deal found 12/8$702
This Mytrip deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/212:15 pmCHS - GYE
3 stops33h 38mSpirit Airlines
mié. 12/2412:49 amGYE - CHS
2 stops12h 21mSpirit Airlines
Deal found 12/6$761
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/178:10 pmCHS - LIM
2 stops28h 40mMultiple Airlines
sáb. 1/1711:33 pmLIM - CHS
1 stop18h 03mMultiple Airlines
Deal found 12/9$762
This American Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/109:25 amCHS - CTG
1 stop12h 05mAmerican Airlines
dom. 12/144:30 pmCTG - CHS
1 stop8h 16mAmerican Airlines
Deal found 12/7$778
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/129:49 pmCHS - LIM
1 stop24h 46mMultiple Airlines
sáb. 12/131:50 amLIM - CHS
2 stops19h 04mMultiple Airlines
Deal found 12/8$800

Find flight deals from Charleston to South America

Keep the following information in mind while searching for Charleston to South America flight deals. Data was last updated diciembre 9, 2025.

Round-trip from

$339
(KAYAK)

One-way from

$139
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$1,804
From Charleston to South America
Search Deals
One-way flight from Charleston to South America
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($224 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 17% potential price decrease ($103 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 9, 2025.
Use the filters below to find and compare flights from Charleston to South America that are best for you.

Fly from

Charleston

Fly to

South America

Route

Depart

Return

Price

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

vie. 1/23

6:35 pm-1:15 pm

1 stop18h 40m

Cartagena Rafael Nunez

vie. 1/30

2:21 pm-5:36 pm

1 stop27h 15m

$274

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

vie. 1/30

6:35 pm-2:15 pm

1 stop19h 40m

Medellín Jose Maria Cordova Intl

dom. 2/8

3:15 pm-5:36 pm

1 stop26h 21m

$339

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

vie. 1/23

3:21 pm-1:15 pm

2 stops21h 54m

Cartagena Rafael Nunez

vie. 1/30

2:21 pm-5:36 pm

1 stop27h 15m

$340

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

vie. 1/23

3:21 pm-12:50 pm

1 stop21h 29m

Bogotá El Dorado

vie. 1/30

1:45 pm-5:36 pm

2 stops27h 51m

$346

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

jue. 1/29

6:35 pm-2:15 pm

1 stop19h 40m

Medellín Jose Maria Cordova Intl

dom. 2/8

5:00 am-8:43 am

2 stops27h 43m

$368

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

mar. 6/2

8:00 pm-4:59 am

1 stop9h 59m

Guayaquil Jose Joaquin de Olmedo

mar. 6/16

6:59 am-7:05 pm

1 stop11h 06m

$373

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

jue. 1/29

6:35 pm-2:15 pm

1 stop19h 40m

Medellín Jose Maria Cordova Intl

dom. 2/8

3:15 pm-5:36 pm

1 stop26h 21m

$373

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

sáb. 1/31

6:35 pm-1:15 pm

1 stop18h 40m

Cartagena Rafael Nunez

lun. 2/9

2:21 pm-11:02 am

2 stops44h 41m

$374

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

jue. 1/29

6:35 pm-2:15 pm

1 stop19h 40m

Medellín Jose Maria Cordova Intl

lun. 2/2

9:54 am-8:38 am

2 stops22h 44m

$378

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

vie. 1/9

6:35 pm-12:21 am

1 stop29h 46m

Guayaquil Jose Joaquin de Olmedo

vie. 1/16

1:26 am-5:36 pm

1 stop16h 10m

$386

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/8

Showing 1-10 of 60 results
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Best time to book a flight from Charleston to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to South America

What is the cheapest month to book a flight from Charleston to South America?

Currently, November is the cheapest month in which you can book a flight from Charleston to South America (average of $113). Flying from Charleston to South America in May is currently the most expensive (average of $530). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to SA?

Find hourly flight availability from Charleston to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 9, 2025.

It’s optimal to fly from Charleston to South America in the morning. By choosing this option you can save up to 23% on the cost of your flight, compared to a flight at noon.

What is the cheapest day to fly from Charleston to South America?

Use this chart to determine the cheapest time to fly round-trip from Charleston to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Charleston to South America flight should consider departing on Wednesday mornings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated diciembre 9, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and American Airlines from Charleston to South America have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,010 reviews

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,010 reviews
Delta
7.9
Good
8,010 reviews

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,889 reviews
Delta
7.9
Good
8,010 reviews

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,043 reviews
Delta
7.9
Good
8,010 reviews

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charleston to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to South America?

    For a flight from Charleston to South America, you will be flying from Charleston. Charleston (CHS) is just 10.2 mi from the center of the city.

  • How long is the flight from Charleston to South America?

    Airlines like Spirit Airlines, JetBlue, and Delta fly from Charleston to South America in about 9h 59m. The time it takes to get you to your destination can typically vary by up to 8h 41m. Charleston and South America are separated by a distance of 2420 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Charleston to South America?

    Most travelers choose Charleston - Quito Mariscal Sucr, Charleston - Lima J Chavez Intl or Charleston - Medellín Jose Maria Cordova Intl when deciding on the best route from Charleston to South America.

  • Can I find deals for flights from Charleston to South America that include hotel bookings?

    Yes. In addition to deals on Charleston to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to South America.

  • Can I find deals for business class flights from Charleston to South America?

    Yes. Cheapflights offers flight deals from Charleston to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to South America?

    Currently, November is the cheapest month in which you can book a flight from Charleston to South America (average of $113). Flying from Charleston to South America in May is currently the most expensive (average of $530). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Charleston to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Charleston to South America

Discover the top 3 airlines that operate flights from Charleston to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 9, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$301Average$863FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$435Average$781FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$542Average$820FlexibilityNo cancel feeOn-time81%

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