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South America

$230+ Cheap flights from Charleston (CHS) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/23. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BOG
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Charleston to South America

Keep the following information in mind while searching for Charleston to South America flight deals. Data was last updated septiembre 11, 2025.

Round-trip from

$380
(Kiwi.com)

One-way from

$230
(Kiwi.com)

Popular in

December

Cheapest in

February

Average price

$869
From Charleston to South America
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One-way flight from Charleston to South America
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Highest demand for flights based on searches. 16% potential increase in price ($187 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($38 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Charleston to South America

Cheapest flights from Charleston to South America
Explore the most affordable flight options available from Charleston to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/145:40 pmCHS - MDE
1 stop20h 36mMultiple Airlines
lun. 11/1710:03 pmMDE - CHS
2 stops36h 42mMultiple Airlines
Deal found 9/10$380
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/88:10 pmCHS - BOG
2 stops18h 05mMultiple Airlines
dom. 10/192:10 pmBOG - CHS
1 stop17h 56mMultiple Airlines
Deal found 9/9$385
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/2610:10 amCHS - BOG
1 stop28h 00mMultiple Airlines
lun. 9/2912:55 pmBOG - CHS
1 stop18h 42mMultiple Airlines
Deal found 9/11$393
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/145:20 pmCHS - MDE
1 stop21h 12mJetBlue
lun. 11/172:10 pmMDE - CHS
1 stop26h 12mJetBlue
Deal found 9/10$395
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/259:40 amCHS - MDE
1 stop28h 52mJetBlue
sáb. 11/11:10 pmMDE - CHS
1 stop27h 12mJetBlue
Deal found 9/10$396
This Mytrip deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/257:55 pmCHS - MDE
2 stops18h 16mSpirit Airlines
vie. 10/311:16 amMDE - CHS
2 stops16h 25mSpirit Airlines
Deal found 9/10$408
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/87:55 pmCHS - BOG
2 stops18h 20mSpirit Airlines
mié. 10/152:10 pmBOG - CHS
1 stop17h 56mSpirit Airlines
Deal found 9/8$408
This Mytrip deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/77:55 pmCHS - MDE
3 stops29h 26mSpirit Airlines
jue. 10/91:16 amMDE - CHS
1 stop6h 50mSpirit Airlines
Deal found 9/10$412
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/711:10 amCHS - MDE
2 stops27h 55mJetBlue
vie. 10/101:30 pmMDE - CHS
1 stop18h 24mJetBlue
Deal found 9/10$429
This Mytrip deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/257:55 pmCHS - MDE
2 stops18h 09mMultiple Airlines
sáb. 11/19:10 amMDE - CHS
3 stops23h 56mMultiple Airlines
Deal found 9/10$454
This Mytrip deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/87:55 pmCHS - BOG
2 stops18h 20mMultiple Airlines
mié. 10/154:25 pmBOG - CHS
2 stops15h 41mMultiple Airlines
Deal found 9/8$472
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/37:05 pmCHS - BOG
2 stops18h 40mDelta
vie. 11/283:55 pmBOG - CHS
1 stop17h 36mDelta
Deal found 9/10$533

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Charleston to South America that are best for you.

Fly from

Charleston

Fly to

South America

Route

Depart

Return

Price

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

vie. 11/14

5:40 pm-2:16 pm

1 stop20h 36m

Medellín Jose Maria Cordova Intl

lun. 11/17

10:03 pm-10:45 am

2 stops36h 42m

$380

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

vie. 11/14

5:20 pm-2:32 pm

1 stop21h 12m

Medellín Jose Maria Cordova Intl

lun. 11/17

2:10 pm-4:22 pm

1 stop26h 12m

$395

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

sáb. 10/25

9:40 am-1:32 pm

1 stop28h 52m

Medellín Jose Maria Cordova Intl

sáb. 11/1

1:10 pm-5:22 pm

1 stop27h 12m

$396

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

sáb. 10/25

7:55 pm-1:11 pm

2 stops18h 16m

Medellín Jose Maria Cordova Intl

vie. 10/31

1:16 am-6:41 pm

2 stops16h 25m

$408

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

mar. 10/7

7:55 pm-12:21 am

3 stops29h 26m

Medellín Jose Maria Cordova Intl

jue. 10/9

1:16 am-9:06 am

1 stop6h 50m

$412

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

vie. 9/26

6:08 pm-1:10 pm

2 stops20h 02m

Bogotá El Dorado

lun. 9/29

12:55 pm-8:37 am

1 stop18h 42m

$430

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

sáb. 10/25

7:55 pm-11:59 pm

3 stops29h 04m

Medellín Jose Maria Cordova Intl

sáb. 11/1

9:10 am-10:06 am

3 stops23h 56m

$470

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

mié. 10/8

7:55 pm-1:15 pm

2 stops18h 20m

Bogotá El Dorado

mié. 10/15

4:25 pm-9:06 am

2 stops15h 41m

$472

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

mar. 3/10

5:30 am-1:35 pm

1 stop9h 05m

Bogotá El Dorado

mié. 3/18

6:35 pm-11:25 am

2 stops15h 50m

$523

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

jue. 2/26

10:23 am-9:51 am

2 stops23h 28m

Medellín Jose Maria Cordova Intl

dom. 3/8

10:46 am-9:55 am

2 stops22h 09m

$535

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 44 results
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Best time to book a flight from Charleston to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to South America

What is the cheapest month to book a flight from Charleston to South America?

Currently, May is the cheapest month in which you can book a flight from Charleston to South America (average of $359). Flying from Charleston to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to SA?

Find hourly flight availability from Charleston to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Charleston to South America as you normally would.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated septiembre 11, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and American Airlines from Charleston to South America have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,847 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Charleston to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to South America?

    For a flight from Charleston to South America, you will be flying from Charleston. Charleston (CHS) is just 10.2 mi from the center of the city.

  • How long is the flight from Charleston to South America?

    Airlines like JetBlue, Spirit Airlines, and Delta fly from Charleston to South America in about 9h 05m. The time it takes to get you to your destination can typically vary by up to 12h 07m. Charleston and South America are separated by a distance of 1983 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Charleston to South America one-way?

    The cheapest airlines for a one-way flight from Charleston to South America are Copa Airlines ($252), American Airlines ($334), and LATAM Airlines ($346).

  • What are the most popular routes from Charleston to South America?

    Most travelers choose Charleston - Lima J Chavez Intl, Charleston - Bogotá El Dorado or Charleston - Buenos Aires Ministro Pistarini when deciding on the best route from Charleston to South America.

  • Can I find deals for flights from Charleston to South America that include hotel bookings?

    Yes. In addition to deals on Charleston to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to South America.

  • Can I find deals for business class flights from Charleston to South America?

    Yes. Cheapflights offers flight deals from Charleston to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to South America?

    Currently, May is the cheapest month in which you can book a flight from Charleston to South America (average of $359). Flying from Charleston to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Charleston to South America

Discover the top 3 airlines that operate flights from Charleston to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$436Average$833FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$458Average$901FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$491Average$857FlexibilityNo cancel feeOn-time81%

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