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South America

$126+ Cheap flights from Charleston (CHS) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BOG
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from Charleston to South America

Cheapest flights from Charleston to South America
Explore the most affordable flight options available from Charleston to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/129:49 pmCHS - BOG
1 stop16h 20mMultiple Airlines
Tue 1/1310:40 pmBOG - CHS
2 stops33h 53mMultiple Airlines
Deal found 11/12$501
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/59:49 pmCHS - BOG
1 stop20h 21mMultiple Airlines
Wed 12/319:00 amBOG - CHS
2 stops28h 10mMultiple Airlines
Deal found 11/12$509
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/129:49 pmCHS - BOG
1 stop16h 20mSpirit Airlines
Fri 1/93:06 pmBOG - CHS
1 stop26h 30mSpirit Airlines
Deal found 11/12$515
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:59 pmCHS - BOG
1 stop21h 53mMultiple Airlines
Tue 1/1310:40 pmBOG - CHS
2 stops33h 53mMultiple Airlines
Deal found 11/12$539
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:55 amCHS - BOG
2 stops37h 17mMultiple Airlines
Wed 12/317:00 amBOG - CHS
1 stop25h 37mMultiple Airlines
Deal found 11/12$558
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:55 amCHS - BOG
2 stops37h 17mMultiple Airlines
Tue 12/309:10 amBOG - CHS
1 stop30h 18mMultiple Airlines
Deal found 11/12$565
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/59:49 pmCHS - BOG
2 stops39h 03mMultiple Airlines
Tue 12/309:10 amBOG - CHS
1 stop30h 18mMultiple Airlines
Deal found 11/12$566
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/129:49 pmCHS - BOG
1 stop16h 20mMultiple Airlines
Mon 1/123:06 pmBOG - CHS
2 stops17h 32mMultiple Airlines
Deal found 11/12$570
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:49 pmCHS - BOG
2 stops15h 03mSpirit Airlines
Fri 1/93:06 pmBOG - CHS
1 stop26h 30mSpirit Airlines
Deal found 11/12$573
This KAYAK deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:50 amCHS - CTG
1 stop6h 35mSpirit Airlines
Wed 12/102:15 pmCTG - CHS
2 stops20h 45mSpirit Airlines
Deal found 11/10$576
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/129:49 pmCHS - BOG
1 stop16h 20mMultiple Airlines
Sat 1/1010:10 amBOG - CHS
2 stops31h 26mMultiple Airlines
Deal found 11/12$576
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:00 amCHS - MDE
1 stop15h 10mAmerican Airlines
Tue 12/161:30 amMDE - CHS
1 stop7h 15mAmerican Airlines
Deal found 11/12$579

Cheap flight deals from Charleston to South America

Keep the following information in mind while searching for Charleston to South America flight deals. Data was last updated November 13, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$276
(KAYAK)

One-way from

$126
(Kiwi.com)
Provider with most accurate pricing for Charleston-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Sao Paulo (SAO) flights.
Search Deals
From Charleston to South America
Search Deals
One-way flight from Charleston to South America
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Charleston to South America that are best for you.

Fly from

Charleston

Fly to

South America

Route

Depart

Return

Price

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Thu 1/22

6:31 pm-1:13 pm

1 stop18h 42m

Cartagena Rafael Nunez

Wed 1/28

2:21 pm-5:36 pm

1 stop27h 15m

$276

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Sun 2/1

6:31 pm-1:13 pm

1 stop18h 42m

Cartagena Rafael Nunez

Sun 2/8

2:21 pm-5:36 pm

1 stop27h 15m

$304

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Thu 1/22

8:59 pm-1:13 pm

2 stops40h 14m

Cartagena Rafael Nunez

Wed 1/28

2:21 pm-5:36 pm

1 stop27h 15m

$342

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Thu 1/8

6:31 pm-12:21 am

1 stop29h 50m

Guayaquil Jose Joaquin de Olmedo

Tue 1/13

1:26 am-8:33 am

2 stops31h 07m

$397

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Fri 1/16

6:31 pm-2:15 pm

1 stop19h 44m

Medellín Jose Maria Cordova Intl

Fri 1/23

3:15 pm-5:36 pm

1 stop26h 21m

$401

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Thu 1/8

5:05 pm-12:21 am

2 stops31h 16m

Guayaquil Jose Joaquin de Olmedo

Tue 1/13

1:26 am-4:10 pm

3 stops38h 44m

$457

CharlestonLima

CHS - LIM

CHSLIM

Charleston

Sun 1/11

6:31 pm-10:35 pm

1 stop28h 04m

Lima J Chavez Intl

Thu 1/15

11:33 pm-5:36 pm

1 stop18h 03m

$467

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Sun 2/1

6:31 pm-8:52 pm

3 stops26h 21m

Cartagena Rafael Nunez

Sun 2/8

2:21 pm-4:10 pm

3 stops25h 49m

$470

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Sun 2/1

7:51 pm-3:30 pm

2 stops19h 39m

Cartagena Rafael Nunez

Sun 2/8

4:30 pm-9:48 am

2 stops17h 18m

$496

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Wed 1/28

8:00 am-2:17 pm

1 stop6h 17m

Cartagena Rafael Nunez

Sun 2/1

3:32 pm-9:24 am

1 stop17h 52m

$497

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/13

Showing 1-10 of 60 results
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Best time to book a flight from Charleston to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to South America

What is the cheapest month to book a flight from Charleston to South America?

Currently, September is the cheapest month in which you can book a flight from Charleston to South America (average of $176). Flying from Charleston to South America in May is currently the most expensive (average of $530). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to SA?

Find hourly flight availability from Charleston to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

It’s optimal to fly from Charleston to South America in the morning. By choosing this option you can save up to 23% on the cost of your flight, compared to a flight at noon.

What is the cheapest day to fly from Charleston to South America?

Use this chart to determine the cheapest time to fly round-trip from Charleston to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Charleston to South America flight should consider departing on Wednesday mornings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated November 13, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and American Airlines from Charleston to South America have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,875 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charleston to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to South America?

    For a flight from Charleston to South America, you will be flying from Charleston. Charleston (CHS) is just 10.2 mi from the center of the city.

  • How long is the flight from Charleston to South America?

    Airlines like Spirit Airlines, Delta, and United Airlines fly from Charleston to South America in about 11h 20m. The time it takes to get you to your destination can typically vary by up to 17h 45m. Charleston and South America are separated by a distance of 1983 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Charleston to South America?

    Most travelers choose Charleston - Medellín Jose Maria Cordova Intl, Charleston - Lima J Chavez Intl or Charleston - Buenos Aires Ministro Pistarini when deciding on the best route from Charleston to South America.

  • Can I find deals for flights from Charleston to South America that include hotel bookings?

    Yes. In addition to deals on Charleston to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to South America.

  • Can I find deals for business class flights from Charleston to South America?

    Yes. Cheapflights offers flight deals from Charleston to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to South America?

    Currently, September is the cheapest month in which you can book a flight from Charleston to South America (average of $176). Flying from Charleston to South America in May is currently the most expensive (average of $530). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Charleston to South America

Discover the top 3 airlines that operate flights from Charleston to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$301Average$882FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$458Average$779FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$542Average$918FlexibilityNo cancel feeOn-time81%

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