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$371+ Cheap flights from South Carolina to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/11. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SCL
Jun 10 — Jun 171
Wed 6/10
Wed 6/17
1 adult, Economy
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Cheap flight deals from South Carolina to Santiago

Cheapest flights from South Carolina to Santiago
Explore the most affordable flight options available from South Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.

This FlightHub deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/91:15 pm
CLT
-
SCL
1 stop16h 35m
LATAM Airlines
Fri 11/2011:55 pm
SCL
-
CLT
1 stop15h 59m
LATAM Airlines
Deal found 5/6$847
This KAYAK deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:59 pm
CLT
-
SCL
2 stops17h 06m
LATAM Airlines
Mon 9/2811:05 pm
SCL
-
CLT
2 stops20h 12m
LATAM Airlines
Deal found 5/6$855
This KAYAK deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/241:15 pm
CLT
-
SCL
1 stop16h 35m
LATAM Airlines
Wed 12/211:55 pm
SCL
-
CLT
1 stop15h 59m
LATAM Airlines
Deal found 5/9$867
This FlightHub deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/241:49 pm
CLT
-
SCL
1 stop16h 36m
LATAM Airlines
Tue 9/111:00 pm
SCL
-
CLT
2 stops19h 17m
LATAM Airlines
Deal found 5/6$877
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:12 am
MYR
-
SCL
2 stops18h 33m
American Airlines
Wed 12/911:45 pm
SCL
-
MYR
1 stop18h 50m
American Airlines
Deal found 5/6$880
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:05 am
CHS
-
SCL
2 stops24h 45m
United Airlines
Wed 11/1110:45 pm
SCL
-
CHS
2 stops21h 21m
United Airlines
Deal found 5/10$880
This KAYAK deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:15 pm
CLT
-
SCL
1 stop16h 35m
LATAM Airlines
Tue 1/197:45 pm
SCL
-
CLT
2 stops20h 09m
LATAM Airlines
Deal found 5/10$885
This FlightHub deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:49 pm
CLT
-
SCL
1 stop16h 36m
LATAM Airlines
Tue 8/2510:55 pm
SCL
-
CLT
1 stop19h 56m
LATAM Airlines
Deal found 5/5$893
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:20 pm
MYR
-
SCL
2 stops39h 30m
United Airlines
Mon 12/710:45 pm
SCL
-
MYR
2 stops17h 48m
United Airlines
Deal found 5/6$898
This Justfly.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:49 pm
CLT
-
SCL
1 stop16h 36m
LATAM Airlines
Mon 8/3111:00 pm
SCL
-
CLT
2 stops19h 17m
LATAM Airlines
Deal found 5/6$905
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:20 pm
MYR
-
SCL
2 stops39h 30m
United Airlines
Tue 12/810:45 pm
SCL
-
MYR
2 stops41h 48m
United Airlines
Deal found 5/6$916
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:35 pm
SAV
-
SCL
1 stop15h 15m
United Airlines
Mon 11/210:45 pm
SCL
-
SAV
1 stop16h 15m
United Airlines
Deal found 5/7$925

Find flight deals from South Carolina to Santiago

Keep the following information in mind while searching for South Carolina to Santiago flight deals. Data was last updated May 11, 2026.

Round-trip from

$855
(KAYAK)

One-way from

$371
(Kiwi.com)
From South Carolina to Santiago Arturo Merino Benitez
Search Deals
One-way flight from South Carolina to Santiago Arturo Merino Benitez
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from South Carolina to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Thu 11/5

4:50 pm-8:50 am

1 stop14h 00m

Santiago Arturo Merino Benitez

Wed 11/11

10:45 pm-6:06 pm

2 stops21h 21m

$880

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 8/12

5:30 pm-6:55 am

2 stops13h 25m

Santiago Arturo Merino Benitez

Mon 8/31

11:00 pm-6:17 pm

2 stops19h 17m

$925
Quickest round-trip

SavannahSantiago

SAV - SCL

SAVSCL

Savannah/Hilton Head

Thu 10/29

3:35 pm-7:50 am

1 stop15h 15m

Santiago Arturo Merino Benitez

Mon 11/2

10:45 pm-1:00 pm

1 stop16h 15m

$925

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Wed 11/4

5:15 pm-8:50 am

1 stop13h 35m

Santiago Arturo Merino Benitez

Tue 2/2

10:45 pm-3:18 pm

1 stop18h 33m

$925

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Thu 10/29

6:05 am-7:50 am

2 stops24h 45m

Santiago Arturo Merino Benitez

Mon 11/2

10:45 pm-6:06 pm

2 stops21h 21m

$930

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Thu 10/29

7:00 am-7:50 am

1 stop23h 50m

Santiago Arturo Merino Benitez

Mon 11/2

10:45 pm-3:18 pm

1 stop18h 33m

$935

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Fri 10/23

4:30 pm-6:55 am

2 stops13h 25m

Santiago Arturo Merino Benitez

Sun 11/1

11:25 pm-6:12 pm

2 stops20h 47m

$938

SavannahSantiago

SAV - SCL

SAVSCL

Savannah/Hilton Head

Wed 10/28

3:35 pm-7:50 am

1 stop15h 15m

Santiago Arturo Merino Benitez

Sun 11/1

10:45 pm-5:40 pm

1 stop20h 55m

$975

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Wed 11/4

7:55 pm-4:30 pm

2 stops18h 35m

Santiago Arturo Merino Benitez

Tue 2/2

12:25 am-6:49 pm

2 stops20h 24m

$996

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Thu 10/29

3:20 pm-7:50 am

2 stops39h 30m

Santiago Arturo Merino Benitez

Mon 11/2

10:45 pm-10:37 am

2 stops37h 52m

$999

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/6

Showing 1-10 of 37 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santiago

How much does it cost to fly round-trip from South Carolina to Santiago?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from South Carolina?

    For a flight from South Carolina to Santiago, you will be flying into Arturo Merino Benitez. Santiago Arturo Merino Benitez (SCL) is just 8.4 mi from the center of the city.

  • How long is the flight from South Carolina to Santiago?

    A quick flight from South Carolina to Santiago can take about 13h 25m. United Airlines provides one of the quickest options available for as low as $925. The distance between South Carolina and Santiago is about 4783 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from South Carolina to Santiago?

    The most popular flight routes from South Carolina to Santiago are Charlotte Douglas - Santiago Arturo Merino Benitez, Charleston - Santiago Arturo Merino Benitez and Myrtle Beach Intl - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from South Carolina to Santiago that include hotel bookings?

    Yes. In addition to deals on South Carolina to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santiago.

  • Can I find deals for business class flights from South Carolina to Santiago?

    Yes. Cheapflights offers flight deals from South Carolina to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from South Carolina to Santiago

Discover the top 2 airlines that operate flights from South Carolina to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$562Average$1,022FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$703Average$883FlexibilityNo cancel feeOn-time71%

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