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$356+ Cheap flights from South Carolina to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SCL
2월 10 — 2월 171
화 2/10
화 2/17
1 adult, Economy
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Cheap flight deals from South Carolina to Santiago

Keep the following information in mind while searching for South Carolina to Santiago flight deals. Data was last updated 1월 11, 2026.

Round-trip from

$548
(Kiwi.com)

One-way from

$356
(Kiwi.com)
From South Carolina to Santiago Arturo Merino Benitez
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One-way flight from South Carolina to Santiago Arturo Merino Benitez
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Find flight deals from South Carolina to Santiago

Cheapest flights from South Carolina to Santiago
Explore the most affordable flight options available from South Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 1월 11, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 3/67:00 amCLT - SCL
2 stops23h 15mMultiple Airlines
금 3/135:50 amSCL - CLT
2 stops29h 17mMultiple Airlines
Deal found 1/10$548
This Kiwi.com deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 3/67:00 amCLT - SCL
2 stops23h 15mMultiple Airlines
월 3/166:00 amSCL - CLT
2 stops31h 19mMultiple Airlines
Deal found 1/8$556
This Kiwi.com deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 3/67:00 amCLT - SCL
2 stops23h 15mMultiple Airlines
일 3/1510:35 amSCL - CLT
1 stop24h 37mMultiple Airlines
Deal found 1/10$565
This Kiwi.com deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 3/67:00 amCLT - SCL
2 stops23h 15mMultiple Airlines
토 3/1410:35 amSCL - CLT
2 stops22h 36mMultiple Airlines
Deal found 1/10$592
This Kiwi.com deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 3/77:00 amCLT - SCL
3 stops27h 00mMultiple Airlines
금 3/1310:35 amSCL - CLT
1 stop24h 32mMultiple Airlines
Deal found 1/10$638
This Avianca Connect deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
월 2/96:00 amCLT - SCL
2 stops21h 30mMultiple Airlines
금 2/204:25 pmSCL - CLT
2 stops21h 55mMultiple Airlines
Deal found 1/8$667
This Avianca Connect deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
목 3/127:00 amCLT - SCL
2 stops21h 30mMultiple Airlines
월 3/234:25 pmSCL - CLT
2 stops20h 54mMultiple Airlines
Deal found 1/9$693
This Avianca Connect deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
수 3/1111:12 amCLT - SCL
2 stops17h 18mMultiple Airlines
월 3/234:25 pmSCL - CLT
2 stops20h 54mMultiple Airlines
Deal found 1/9$699
This Kiwi.com deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
일 3/87:48 pmCLT - SCL
2 stops23h 32mMultiple Airlines
일 3/1510:35 amSCL - CLT
1 stop24h 37mMultiple Airlines
Deal found 1/10$709
This Delta deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
월 2/237:00 pmCHS - SCL
2 stops18h 30mDelta
월 3/26:30 pmSCL - CHS
2 stops21h 30mDelta
Deal found 1/9$783
This American Airlines deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
수 5/611:04 amCHS - SCL
1 stop19h 46mAmerican Airlines
금 5/158:30 pmSCL - CHS
1 stop16h 17mAmerican Airlines
Deal found 1/10$784
This Ovago deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
수 3/43:07 pmCHS - SCL
1 stop14h 33mLATAM Airlines
일 3/86:30 pmSCL - CHS
2 stops23h 39mLATAM Airlines
Deal found 1/9$795

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated 1월 11, 2026.
Use the filters below to find and compare flights from South Carolina to Santiago that are best for you.

Fly from

South Carolina

Fly to

Santiago

Route

Depart

Return

Price

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

금 3/6

7:00 am-8:15 am

2 stops23h 15m

Santiago Arturo Merino Benitez

금 3/13

10:35 am-10:07 am

1 stop24h 32m

$565

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

금 3/6

7:00 am-8:15 am

2 stops23h 15m

Santiago Arturo Merino Benitez

일 3/15

12:28 pm-10:12 am

2 stops22h 44m

$572

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

금 3/6

7:00 am-8:15 am

2 stops23h 15m

Santiago Arturo Merino Benitez

토 3/14

10:35 am-8:11 am

2 stops22h 36m

$592

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

월 2/9

6:00 am-5:30 am

2 stops21h 30m

Santiago Arturo Merino Benitez

금 2/20

4:25 pm-12:20 pm

2 stops21h 55m

$667

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

목 3/12

7:00 am-5:30 am

2 stops21h 30m

Santiago Arturo Merino Benitez

월 3/23

4:25 pm-12:19 pm

2 stops20h 54m

$693

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

수 3/11

11:12 am-5:30 am

2 stops17h 18m

Santiago Arturo Merino Benitez

월 3/23

4:25 pm-12:19 pm

2 stops20h 54m

$699

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

토 2/7

6:00 am-5:14 am

2 stops21h 14m

Santiago Arturo Merino Benitez

토 2/28

10:35 am-12:20 pm

1 stop27h 45m

$731

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

토 3/7

9:23 pm-4:55 am

2 stops29h 32m

Santiago Arturo Merino Benitez

금 3/13

11:25 pm-12:19 pm

1 stop13h 54m

$733

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

토 3/7

7:00 am-12:00 pm

3 stops27h 00m

Santiago Arturo Merino Benitez

토 3/14

11:25 pm-12:19 pm

1 stop13h 54m

$745

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

화 3/17

3:25 pm-5:55 am

1 stop13h 30m

Santiago Arturo Merino Benitez

화 3/24

5:15 am-11:48 pm

2 stops19h 33m

$748

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/8

Showing 1-10 of 35 results
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Best time to book a flight from South Carolina to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santiago
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from South Carolina?

    For a flight from South Carolina to Santiago, you will be flying into Arturo Merino Benitez. Santiago Arturo Merino Benitez (SCL) is just 8.4 mi from the center of the city.

  • How long is the flight from South Carolina to Santiago?

    A quick flight from South Carolina to Santiago can take about 13h 40m. LATAM Airlines provides one of the quickest options available for as low as $783. The distance between South Carolina and Santiago is about 4616 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from South Carolina to Santiago?

    The most popular flight routes from South Carolina to Santiago are Charlotte Douglas - Santiago Arturo Merino Benitez, Charleston - Santiago Arturo Merino Benitez and Savannah/Hilton Head - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from South Carolina to Santiago that include hotel bookings?

    Yes. In addition to deals on South Carolina to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santiago.

  • Can I find deals for business class flights from South Carolina to Santiago?

    Yes. Cheapflights offers flight deals from South Carolina to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for South Carolina to Santiago

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Top 3 airlines flying from South Carolina to Santiago

Discover the top 3 airlines that operate flights from South Carolina to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated 1월 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$571Average$901FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$703Average$845FlexibilityNo cancel feeOn-time71%
DeltaCheapest$793Average$948FlexibilityNo cancel feeOn-timeN/A

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