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$317+ Cheap flights from South Carolina to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SCL
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from South Carolina to Santiago

Keep the following information in mind while searching for South Carolina to Santiago flight deals. Data was last updated January 8, 2026.

Round-trip from

$569
(Avianca Connect)

One-way from

$317
(Kiwi.com)
From South Carolina to Santiago Arturo Merino Benitez
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One-way flight from South Carolina to Santiago Arturo Merino Benitez
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Find flight deals from South Carolina to Santiago

Cheapest flights from South Carolina to Santiago
Explore the most affordable flight options available from South Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This Avianca Connect deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:30 amCLT - SCL
2 stops21h 45mMultiple Airlines
Wed 4/2211:55 pmSCL - CLT
2 stops20h 34mMultiple Airlines
Deal found 1/5$569
This Avianca Connect deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2411:12 amCLT - SCL
2 stops17h 18mMultiple Airlines
Mon 3/303:30 pmSCL - CLT
2 stops21h 49mMultiple Airlines
Deal found 1/5$616
This Ovago deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:30 amCHS - SCL
1 stop23h 10mLATAM Airlines
Thu 2/266:35 pmSCL - CHS
2 stops21h 25mLATAM Airlines
Deal found 1/6$670
This Avianca Connect deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1211:12 amCLT - SCL
2 stops17h 18mMultiple Airlines
Sun 3/221:35 amSCL - CLT
2 stops19h 48mMultiple Airlines
Deal found 1/6$680
This FlightHub deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/22:10 pmCLT - SCL
1 stop14h 45mLATAM Airlines
Mon 3/1610:30 pmSCL - CLT
1 stop17h 15mLATAM Airlines
Deal found 1/6$685
This eDestinos deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/79:59 pmCLT - SCL
2 stops31h 41mMultiple Airlines
Sat 2/289:10 pmSCL - CLT
2 stops44h 35mMultiple Airlines
Deal found 1/7$692
This Delta deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:04 pmCHS - SCL
1 stop18h 46mDelta
Wed 5/1310:55 pmSCL - CHS
1 stop17h 49mDelta
Deal found 1/5$705
This Gurufare deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/24:50 pmGSP - SCL
1 stop14h 00mMultiple Airlines
Tue 2/1010:45 pmSCL - GSP
2 stops20h 07mMultiple Airlines
Deal found 1/6$708
This Ovago deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1212:43 pmCLT - SCL
1 stop17h 57mLATAM Airlines
Mon 3/236:40 amSCL - CLT
2 stops18h 08mLATAM Airlines
Deal found 1/6$713
This United Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/44:45 pmCLT - SCL
1 stop14h 05mUnited Airlines
Wed 2/1110:45 pmSCL - CLT
1 stop14h 02mUnited Airlines
Deal found 1/5$715
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/26:56 pmGSP - SCL
1 stop12h 04mAmerican Airlines
Tue 2/1010:35 pmSCL - GSP
1 stop21h 51mAmerican Airlines
Deal found 1/6$715
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/144:49 pmCLT - SCL
2 stops34h 06mMultiple Airlines
Mon 2/238:25 amSCL - CLT
2 stops29h 55mMultiple Airlines
Deal found 1/7$718

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from South Carolina to Santiago that are best for you.

Fly from

South Carolina

Fly to

Santiago

Route

Depart

Return

Price

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Tue 3/24

11:12 am-5:30 am

2 stops17h 18m

Santiago Arturo Merino Benitez

Mon 3/30

3:30 pm-12:19 pm

2 stops21h 49m

$616

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Thu 2/19

6:30 am-7:40 am

1 stop23h 10m

Santiago Arturo Merino Benitez

Thu 2/26

6:35 pm-2:00 pm

2 stops21h 25m

$670

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Thu 3/12

11:12 am-5:30 am

2 stops17h 18m

Santiago Arturo Merino Benitez

Sun 3/22

1:35 am-8:23 pm

2 stops19h 48m

$680

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 3/2

2:10 pm-6:55 am

1 stop14h 45m

Santiago Arturo Merino Benitez

Mon 3/16

10:30 pm-2:45 pm

1 stop17h 15m

$685

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Tue 3/24

3:25 pm-5:55 am

1 stop13h 30m

Santiago Arturo Merino Benitez

Mon 3/30

11:55 pm-2:45 pm

1 stop15h 50m

$685

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Wed 5/6

12:04 pm-6:50 am

1 stop18h 46m

Santiago Arturo Merino Benitez

Mon 5/18

8:40 pm-1:45 pm

1 stop17h 05m

$705

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Tue 5/5

4:33 pm-7:15 am

1 stop14h 42m

Santiago Arturo Merino Benitez

Mon 5/18

8:40 pm-1:45 pm

1 stop17h 05m

$705

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Tue 5/5

5:59 pm-2:05 pm

2 stops20h 06m

Santiago Arturo Merino Benitez

Thu 5/14

7:45 pm-4:51 pm

2 stops21h 06m

$705

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Tue 5/5

7:30 am-5:45 am

2 stops22h 15m

Santiago Arturo Merino Benitez

Tue 5/12

11:05 pm-11:56 pm

2 stops24h 51m

$705

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Thu 5/7

5:55 pm-7:15 am

1 stop13h 20m

Santiago Arturo Merino Benitez

Thu 5/14

7:45 am-11:56 pm

2 stops16h 11m

$705

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Showing 1-10 of 45 results
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Best time to book a flight from South Carolina to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santiago
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from South Carolina?

    For a flight from South Carolina to Santiago, you will be flying into Arturo Merino Benitez. Santiago Arturo Merino Benitez (SCL) is just 8.4 mi from the center of the city.

  • How long is the flight from South Carolina to Santiago?

    A quick flight from South Carolina to Santiago can take about 15h 27m. LATAM Airlines provides one of the quickest options available for as low as $715. The distance between South Carolina and Santiago is about 4574 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from South Carolina to Santiago?

    The most popular flight routes from South Carolina to Santiago are Charlotte Douglas - Santiago Arturo Merino Benitez, Charleston - Santiago Arturo Merino Benitez and Savannah/Hilton Head - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from South Carolina to Santiago that include hotel bookings?

    Yes. In addition to deals on South Carolina to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santiago.

  • Can I find deals for business class flights from South Carolina to Santiago?

    Yes. Cheapflights offers flight deals from South Carolina to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for South Carolina to Santiago

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Top 3 airlines flying from South Carolina to Santiago

Discover the top 3 airlines that operate flights from South Carolina to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$571Average$901FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$703Average$844FlexibilityNo cancel feeOn-time71%
DeltaCheapest$793Average$948FlexibilityNo cancel feeOn-timeN/A

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