How long is the flight from South Carolina to Santiago?

A quick flight from South Carolina to Santiago can take about 13h 30m. LATAM Airlines provides one of the quickest options available for as low as $684. The distance between South Carolina and Santiago is about 4783 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

What are the most popular routes from South Carolina to Santiago?

The most popular flight routes from South Carolina to Santiago are Charlotte Douglas - Santiago Arturo Merino Benitez, Charleston - Santiago Arturo Merino Benitez and Greenville - Santiago Arturo Merino Benitez.

What is the cheapest time of day to fly from SC to SCL?

When flying from South Carolina to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What airport do you fly into for flights to Santiago from South Carolina?

For a flight from South Carolina to Santiago, you will be flying into Arturo Merino Benitez. Santiago Arturo Merino Benitez (SCL) is just 8.4 mi from the center of the city.

Can I find deals for flights from South Carolina to Santiago that include hotel bookings?

Yes. In addition to deals on South Carolina to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from South Carolina to Santiago?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santiago.

Can I find deals for business class flights from South Carolina to Santiago?

Yes. Cheapflights offers flight deals from South Carolina to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$260+ Flights from South Carolina to Santiago

Q: How much does it cost to fly round-trip from South Carolina to Santiago?

Airfare is below average for this route at the moment. South Carolina to Santiago flights typically cost between $735 and $797 in January. The cheapest round-trip price found within the last 3 days was $704 on LATAM Airlines (Jan 31-Feb 5).

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from South Carolina to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Santiago

Cheapest flights from South Carolina to Santiago
Explore the most affordable flight options available from South Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 27, 2025.

Mon 12/294:09 pmCHS - SCL

2 stops19h 56mLATAM Airlines

Wed 12/3111:10 pmSCL - CHS

1 stop14h 26mLATAM Airlines

Deal found 12/25

$1,296

Mon 12/296:35 amCHS - SCL

3 stops29h 55mMultiple Airlines

Wed 12/314:25 pmSCL - CHS

2 stops28h 58mMultiple Airlines

Deal found 12/25

$1,535

Sat 12/277:03 pmCHS - SCL

2 stops32h 27mMultiple Airlines

Thu 1/11:35 amSCL - CHS

2 stops18h 32mMultiple Airlines

Deal found 12/26

$1,735

Thu 12/2512:23 pmCHS - SCL

3 stops24h 07mLATAM Airlines

Fri 1/212:10 amSCL - CHS

2 stops25h 48mLATAM Airlines

Deal found 12/25

$1,954

Sat 12/275:58 pmCHS - SCL

1 stop11h 42mLATAM Airlines

Fri 1/28:10 amSCL - CHS

2 stops17h 48mLATAM Airlines

Deal found 12/26

$1,957

Thu 12/257:03 pmCHS - SCL

2 stops32h 27mMultiple Airlines

Fri 1/21:35 amSCL - CHS

2 stops18h 31mMultiple Airlines

Deal found 12/25

$1,999

Sat 12/275:00 pmCHS - SCL

1 stop13h 50mUnited Airlines

Fri 1/210:45 pmSCL - CHS

1 stop19h 25mUnited Airlines

Deal found 12/26

$2,139

Best flights from South Carolina to Santiago
Discover carefully curated flight deals from South Carolina to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 27, 2025.

Tue 3/103:25 pmCLT - SCL

1 stop13h 30mLATAM Airlines

Mon 3/1610:30 pmSCL - CLT

1 stop17h 15mLATAM Airlines

Deal found 12/27

$684

Mon 2/96:00 amCLT - SCL

2 stops21h 30mMultiple Airlines

Mon 2/164:25 pmSCL - CLT

2 stops21h 55mMultiple Airlines

Deal found 12/26

$703

Thu 1/153:16 pmCHS - SCL

1 stop14h 59mAmerican Airlines

Sat 1/2410:30 pmSCL - CHS

1 stop17h 55mAmerican Airlines

Deal found 12/25

$704

Thu 3/193:23 pmSAV - SCL

1 stop15h 27mUnited Airlines

Mon 3/239:45 pmSCL - SAV

1 stop16h 29mUnited Airlines

Deal found 12/26

$714

Tue 2/104:00 pmMYR - SCL

1 stop13h 40mDelta

Tue 2/1711:10 pmSCL - MYR

1 stop17h 52mDelta

Deal found 12/26

$756

Mon 3/22:10 pmCLT - SCL

1 stop14h 45mLATAM Airlines

Mon 3/164:35 amSCL - CLT

2 stops20h 13mLATAM Airlines

Deal found 12/26

$699

Sat 1/313:16 pmCHS - SCL

1 stop14h 59mAmerican Airlines

Thu 2/511:55 pmSCL - CHS

1 stop20h 53mAmerican Airlines

Deal found 12/24

$704

Mon 3/2311:12 amCLT - SCL

2 stops17h 18mMultiple Airlines

Fri 3/271:35 amSCL - CLT

2 stops19h 48mMultiple Airlines

Deal found 12/26

$711

Mon 2/94:54 pmCLT - SCL

1 stop12h 46mLATAM Airlines

Mon 2/1610:35 amSCL - CLT

2 stops15h 14mLATAM Airlines

Deal found 12/26

$702

Wed 2/45:30 pmCHS - SCL

1 stop12h 10mLATAM Airlines

Fri 2/135:15 amSCL - CHS

2 stops19h 20mLATAM Airlines

Deal found 12/26

$704

Sat 1/318:00 amCHS - SCL

2 stops18h 30mLATAM Airlines

Thu 2/511:10 pmSCL - CHS

1 stop20h 43mLATAM Airlines

Deal found 12/24

$704

Wed 4/17:12 pmGSP - SCL

1 stop11h 53mAmerican Airlines

Wed 4/158:50 pmSCL - GSP

1 stop21h 21mAmerican Airlines

Deal found 12/26

$854

Tue 2/104:00 pmMYR - SCL

2 stops21h 30mLATAM Airlines

Tue 2/1711:10 pmSCL - MYR

1 stop12h 35mLATAM Airlines

Deal found 12/26

$714

Fri 4/106:44 pmGSP - SCL

1 stop12h 21mAmerican Airlines

Sat 4/188:50 pmSCL - GSP

1 stop21h 21mAmerican Airlines

Deal found 12/27

$934

Mon 2/162:26 pmCLT - SCL

1 stop15h 14mLATAM Airlines

Wed 2/2512:10 amSCL - CLT

2 stops25h 39mLATAM Airlines

Deal found 12/26

$714

Wed 3/45:55 pmSAV - SCL

2 stops22h 00mLATAM Airlines

Sun 3/84:20 pmSCL - SAV

2 stops30h 51mLATAM Airlines

Deal found 12/25

$714

Thu 3/194:57 pmSAV - SCL

1 stop13h 43mLATAM Airlines

Mon 3/235:15 amSCL - SAV

2 stops19h 38mLATAM Airlines

Deal found 12/26

$714

Fri 2/206:55 pmMYR - SCL

1 stop34h 45mLATAM Airlines

Fri 2/276:30 pmSCL - MYR

2 stops17h 10mLATAM Airlines

Deal found 12/26

$739

Fri 4/107:59 pmGSP - SCL

3 stops25h 16mLATAM Airlines

Sat 4/189:10 pmSCL - GSP

2 stops39h 10mLATAM Airlines

Deal found 12/27

$999

Fri 4/107:59 pmGSP - SCL

1 stop11h 16mLATAM Airlines

Tue 4/147:45 pmSCL - GSP

2 stops23h 40mLATAM Airlines

Deal found 12/25

$1,184

Last-minute flights from South Carolina to Santiago
Discover last-minute flight deals from South Carolina to Santiago. Data last updated December 27, 2025 and is based on user searches.

Mon 12/294:09 pmCHS - SCL

2 stops19h 56mLATAM Airlines

Wed 12/3111:10 pmSCL - CHS

1 stop14h 26mLATAM Airlines

Deal found 12/25

$1,296

Sat 1/32:57 pmCLT - SCL

1 stop14h 03mMultiple Airlines

Sat 1/108:15 amSCL - CLT

2 stops30h 07mMultiple Airlines

Deal found 12/27

$1,307

Sun 1/42:43 pmCLT - SCL

1 stop15h 12mAmerican Airlines

Sun 5/108:50 pmSCL - CLT

1 stop22h 27mAmerican Airlines

Deal found 12/27

$814

Wed 1/75:18 pmCHS - SCL

1 stop12h 22mLATAM Airlines

Sat 1/1010:15 pmSCL - CHS

2 stops27h 40mLATAM Airlines

Deal found 12/26

$1,349

Fri 1/91:13 pmCHS - SCL

2 stops17h 37mUnited Airlines

Mon 1/1210:45 pmSCL - CHS

1 stop19h 32mUnited Airlines

Deal found 12/26

$922

Wed 1/144:56 pmCLT - SCL

1 stop13h 19mAmerican Airlines

Tue 5/58:50 pmSCL - CLT

1 stop13h 37mAmerican Airlines

Deal found 12/26

$734

Wed 1/146:00 amCLT - SCL

2 stops21h 30mMultiple Airlines

Tue 5/511:55 pmSCL - CLT

2 stops20h 34mMultiple Airlines

Deal found 12/26

$771

Wed 1/142:25 pmCLT - SCL

3 stops22h 05mLATAM Airlines

Tue 5/57:45 amSCL - CLT

2 stops16h 08mLATAM Airlines

Deal found 12/26

$1,081

Thu 1/155:13 pmCHS - SCL

1 stop13h 37mUnited Airlines

Sat 1/2410:45 pmSCL - CHS

2 stops22h 19mUnited Airlines

Deal found 12/25

$709

Sun 1/256:53 pmCLT - SCL

1 stop34h 02mLATAM Airlines

Sun 2/110:15 pmSCL - CLT

2 stops27h 39mLATAM Airlines

Deal found 12/27

$750

Sun 1/259:19 pmCLT - SCL

2 stops22h 31mMultiple Airlines

Sun 2/19:05 pmSCL - CLT

2 stops42h 46mMultiple Airlines

Deal found 12/26

$1,234

Sat 1/3110:31 amCHS - SCL

2 stops29h 24mLATAM Airlines

Thu 2/58:50 amSCL - CHS

2 stops17h 05mLATAM Airlines

Deal found 12/26

$704

One-way flights from South Carolina to Santiago
Search for one-way flight options from South Carolina to Santiago. Find affordable one-way fares based on user searches. Data last updated December 27, 2025.

Thu 1/227:00 amCLT - SCL

2 stops18h 35mMultiple Airlines

Deal found 12/25

$260

Mon 3/239:37 pmCLT - SCL

2 stops23h 38mMultiple Airlines

Deal found 12/27

$273

Mon 1/52:57 pmCLT - SCL

2 stops29h 18mMultiple Airlines

Deal found 12/27

$285

Sun 1/47:42 pmCLT - SCL

2 stops32h 58mMultiple Airlines

Deal found 12/27

$287

Fri 5/13:21 pmCHS - SCL

2 stops46h 04mMultiple Airlines

Deal found 12/26

$307

Sat 1/39:02 pmCLT - SCL

2 stops29h 12mMultiple Airlines

Deal found 12/27

$355

Thu 1/17:42 pmCLT - SCL

2 stops24h 33mMultiple Airlines

Deal found 12/27

$358

Fri 1/29:04 pmCLT - SCL

2 stops45h 16mMultiple Airlines

Deal found 12/27

$367

Wed 2/45:55 pmCHS - SCL

3 stops43h 25mMultiple Airlines

Deal found 12/26

$413

Wed 2/45:13 pmCHS - SCL

1 stop13h 37mUnited Airlines

Deal found 12/26

$493

Mon 1/121:45 pmGSP - SCL

2 stops16h 30mAmerican Airlines

Deal found 12/27

$568

Thu 1/12:33 pmCHS - SCL

2 stops16h 52mAmerican Airlines

Deal found 12/26

$578

Find flight deals from South Carolina to Santiago

Round-trip from	$575 (Avianca Connect)
One-way from	$260 (Trip.com)

From South Carolina to Santiago Arturo Merino Benitez

Search Deals

One-way flight from South Carolina to Santiago Arturo Merino Benitez

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Tue 3/10

3:25 pm-5:55 am

1 stop13h 30m

Santiago Arturo Merino Benitez

Mon 3/16

10:30 pm-2:45 pm

1 stop17h 15m

$684

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 3/2

2:10 pm-6:55 am

1 stop14h 45m

Santiago Arturo Merino Benitez

Mon 3/16

4:35 am-11:48 pm

2 stops20h 13m

$699

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 2/9

4:54 pm-7:40 am

1 stop12h 46m

Santiago Arturo Merino Benitez

Mon 2/16

10:35 am-11:49 pm

2 stops15h 14m

$702

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 2/9

6:00 am-5:30 am

2 stops21h 30m

Santiago Arturo Merino Benitez

Mon 2/16

4:25 pm-12:20 pm

2 stops21h 55m

$703

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Thu 1/15

3:16 pm-8:15 am

1 stop14h 59m

Santiago Arturo Merino Benitez

Sat 1/24

10:30 pm-2:25 pm

1 stop17h 55m

$704

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Sat 1/31

3:16 pm-8:15 am

1 stop14h 59m

Santiago Arturo Merino Benitez

Thu 2/5

11:55 pm-6:48 pm

1 stop20h 53m

$704

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Wed 2/4

5:30 pm-7:40 am

1 stop12h 10m

Santiago Arturo Merino Benitez

Fri 2/13

5:15 am-10:35 pm

2 stops19h 20m

$704

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Sat 1/31

8:00 am-4:30 am

2 stops18h 30m

Santiago Arturo Merino Benitez

Thu 2/5

11:10 pm-5:53 pm

1 stop20h 43m

$704

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 3/23

11:12 am-5:30 am

2 stops17h 18m

Santiago Arturo Merino Benitez

Fri 3/27

1:35 am-8:23 pm

2 stops19h 48m

$711

SavannahSantiago

SAV - SCL

SAVSCL

Savannah/Hilton Head

Thu 3/19

3:23 pm-7:50 am

1 stop15h 27m

Santiago Arturo Merino Benitez

Mon 3/23

9:45 pm-1:14 pm

1 stop16h 29m

$714

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/25

Showing 1-10 of 35 results

Best time to book a flight from South Carolina to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from South Carolina with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santiago

How much does it cost to fly round-trip from South Carolina to Santiago?

Related info for your journey

What airport do you fly into for flights to Santiago from South Carolina?
For a flight from South Carolina to Santiago, you will be flying into Arturo Merino Benitez. Santiago Arturo Merino Benitez (SCL) is just 8.4 mi from the center of the city.
How long is the flight from South Carolina to Santiago?
A quick flight from South Carolina to Santiago can take about 13h 30m. LATAM Airlines provides one of the quickest options available for as low as $684. The distance between South Carolina and Santiago is about 4783 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the most popular routes from South Carolina to Santiago?
The most popular flight routes from South Carolina to Santiago are Charlotte Douglas - Santiago Arturo Merino Benitez, Charleston - Santiago Arturo Merino Benitez and Greenville - Santiago Arturo Merino Benitez.
Can I find deals for flights from South Carolina to Santiago that include hotel bookings?
Yes. In addition to deals on South Carolina to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from South Carolina to Santiago?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santiago.
Can I find deals for business class flights from South Carolina to Santiago?
Yes. Cheapflights offers flight deals from South Carolina to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for South Carolina to Santiago

John F Kennedy Intl to Santiago flights

Miami to Santiago flights

Los Angeles to Santiago flights

LaGuardia to Santiago flights

Newark to Santiago flights

San Francisco to Santiago flights

Denver to Santiago flights

Dulles Intl to Santiago flights

Baltimore to Santiago flights

Boston to Santiago flights

Reagan-National to Santiago flights

Atlanta to Santiago flights

Seattle to Santiago flights

Dallas/Fort Worth to Santiago flights

Hobby to Santiago flights

Austin to Santiago flights

Orlando to Santiago flights

George Bush Intcntl to Santiago flights

O'Hare Intl to Santiago flights

Minneapolis to Santiago flights

Philadelphia to Santiago flights

Tampa to Santiago flights

Fort Lauderdale to Santiago flights

Midway to Santiago flights

San Diego to Santiago flights

Kansas City to Santiago flights

Detroit to Santiago flights

Ontario to Santiago flights

Cincinnati to Santiago flights

Las Vegas to Santiago flights

Reagan-National to Punta Arenas flights

Cleveland to Santiago flights

Raleigh to Santiago flights

Salt Lake City to Santiago flights

Charlotte to Santiago flights

Portland to Santiago flights

Orlando Sanford Intl to Santiago flights

St. Louis to Santiago flights

Sky Harbor Intl to Santiago flights

Love Field to Santiago flights

John F Kennedy Intl to Easter Island flights

John F Kennedy Intl to Balmaceda flights

Boston to Punta Arenas flights

Grand Rapids to Santiago flights

Richmond to Santiago flights

Columbus to Santiago flights

Des Moines to Santiago flights

Pittsburgh to Santiago flights

San Francisco to Punta Arenas flights

Hartford to Santiago flights

Other flights to Santiago

Santiago to Concepción flights

Santiago to La Serena flights

Santiago to Calama flights

Santiago to Valdivia flights

Santiago to Mendoza flights

Santiago to Iquique flights

Santiago to Osorno flights

Santiago to Temuco flights

Santiago to Osorno flights

Santiago to Antofagasta flights

Santiago to Calama flights

Santiago to La Serena flights

Santiago to Arica flights

Santiago to Puerto Montt flights

Santiago to Buenos Aires Jorge Newbery Airport flights

Santiago to Buenos Aires Ministro Pistarini Airport flights

Santiago to Arica flights

Santiago to Buenos Aires Jorge Newbery Airport flights

Top 2 airlines flying from South Carolina to Santiago

Airline	Cheapest	Average	Flexibility	On-time
LATAM Airlines	Cheapest$571	Average$901	FlexibilityNo cancel fee	On-time81%
Delta	Cheapest$793	Average$948	FlexibilityNo cancel fee	On-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$260+ Cheap flights from South Carolina to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from South Carolina to Santiago with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from South Carolina to Santiago

Cheapest flights from South Carolina to SantiagoExplore the most affordable flight options available from South Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 27, 2025.

Explore the most affordable flight options available from South Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 27, 2025.

Find flight deals from South Carolina to Santiago

Keep the following information in mind while searching for South Carolina to Santiago flight deals. Data was last updated December 27, 2025.

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Santiago that are best for you.

Best time to book a flight from South Carolina to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from South Carolina with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santiago

How much does it cost to fly round-trip from South Carolina to Santiago?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santiago from South Carolina?

How long is the flight from South Carolina to Santiago?

What are the most popular routes from South Carolina to Santiago?

Can I find deals for flights from South Carolina to Santiago that include hotel bookings?

How can I find direct flights from South Carolina to Santiago?

Can I find deals for business class flights from South Carolina to Santiago?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Santiago

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from South Carolina to Santiago

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from South Carolina to Santiago
Explore the most affordable flight options available from South Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 27, 2025.