$308+ Cheap flights from South Carolina to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/16. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from South Carolina to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Santiago
Keep the following information in mind while searching for South Carolina to Santiago flight deals. Data was last updated June 12, 2025.
Round-trip from | $739 (Justfly.com) |
|---|---|
One-way from | $308 (Kiwi.com) |
Find flight deals from South Carolina to Santiago
Cheapest flights from South Carolina to SantiagoExplore the most affordable flight options available from South Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.
Explore the most affordable flight options available from South Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Justfly.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Justfly.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This LATAM Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Cheapflightsfares deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from South Carolina to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
CharlotteSantiago
CLT - SCL
CLTSCL
Charlotte Douglas
Sun 8/17
9:28 pm-4:15 am
2 stops30h 47m
Santiago Arturo Merino Benitez
Sun 8/24
11:00 am-12:38 pm
1 stop25h 38m
CharlotteSantiago
CLT - SCL
CLTSCL
Charlotte Douglas
Tue 11/4
11:45 am-7:00 am
1 stop17h 15m
Santiago Arturo Merino Benitez
Tue 11/11
11:15 pm-11:03 am
1 stop13h 48m
SavannahSantiago
SAV - SCL
SAVSCL
Savannah/Hilton Head
Wed 10/22
12:26 pm-6:40 am
2 stops17h 14m
Santiago Arturo Merino Benitez
Wed 10/29
8:15 am-11:59 pm
2 stops16h 44m
GreenvilleSantiago
GSP - SCL
GSPSCL
Greenville
Wed 10/15
7:46 pm-8:05 am
1 stop11h 19m
Santiago Arturo Merino Benitez
Mon 10/27
10:15 pm-5:41 pm
1 stop20h 26m
SavannahSantiago
SAV - SCL
SAVSCL
Savannah/Hilton Head
Thu 11/13
5:42 pm-5:14 am
3 stops33h 32m
Santiago Arturo Merino Benitez
Sun 11/16
5:59 am-11:55 am
2 stops31h 56m
GreenvilleSantiago
GSP - SCL
GSPSCL
Greenville
Wed 10/15
5:05 pm-7:00 am
1 stop12h 55m
Santiago Arturo Merino Benitez
Sun 10/26
12:25 am-6:49 pm
2 stops19h 24m
CharlotteSantiago
CLT - SCL
CLTSCL
Charlotte Douglas
Wed 10/1
10:05 am-8:05 am
1 stop21h 00m
Santiago Arturo Merino Benitez
Tue 10/14
9:55 pm-1:06 pm
2 stops16h 11m
GreenvilleSantiago
GSP - SCL
GSPSCL
Greenville
Wed 10/15
12:00 pm-6:40 am
2 stops17h 40m
Santiago Arturo Merino Benitez
Sun 10/26
12:25 am-6:49 pm
2 stops19h 24m
SavannahSantiago
SAV - SCL
SAVSCL
Savannah/Hilton Head
Wed 10/22
8:18 pm-8:05 am
1 stop10h 47m
Santiago Arturo Merino Benitez
Wed 10/29
9:15 pm-12:05 am
1 stop27h 50m
SavannahSantiago
SAV - SCL
SAVSCL
Savannah/Hilton Head
Fri 11/14
3:50 pm-3:00 pm
2 stops21h 10m
Santiago Arturo Merino Benitez
Sat 2/14
8:40 pm-9:20 am
2 stops14h 40m
Best time to book a flight from South Carolina to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from South Carolina with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Santiago
What is the cheapest month to book a flight from South Carolina to Santiago?
Currently, April is the cheapest month in which you can book a flight from South Carolina to Santiago (average of $752). Flying from South Carolina to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to SCL?
Find hourly flight availability from South Carolina to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.
When flying from South Carolina to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Rainfall in Santiago by month
Plan your trip to Santiago by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.
Temperature in Santiago by month
Plan your trip to Santiago by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated June 12, 2025.
To help decide which airline to fly from South Carolina to Santiago, see what other customers have to say about Delta, LATAM Airlines and Qantas Airways. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
Comfort
Food
Overall
Entertainment
Crew
Reviews
Kim,May 2025
PIH - SLC
Boarding
Comfort
Food
Overall
Entertainment
Crew
Reviews
Kim,May 2025
PIH - SLC
Boarding
Comfort
Food
Overall
Entertainment
Crew
Reviews
Kim,May 2025
PIH - SLC
Boarding
Comfort
Food
Overall
Entertainment
Crew
Reviews
Kim,May 2025
PIH - SLC
Boarding
Comfort
Food
Overall
Entertainment
Crew
Reviews
Kim,May 2025
PIH - SLC
Boarding
Comfort
Food
Overall
Entertainment
Crew
Reviews
Kim,May 2025
PIH - SLC
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for South Carolina to Santiago
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from South Carolina to Santiago
Discover the top 2 airlines that operate flights from South Carolina to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$532 | Average$920 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$603 | Average$882 | FlexibilityNo cancel fee | On-time81% |