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$205+ Cheap flights from Indiana to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/19. Fares are subject to change and may not be available on all flights or dates of travel.
IND — SCL
Mar 13 — Mar 201
Fri 3/13
Fri 3/20
1 adult, Economy
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Cheap flight deals from Indiana to Santiago

Cheapest flights from Indiana to Santiago
Explore the most affordable flight options available from Indiana to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.

This Mytrip deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:55 am
ORD
-
SCL
3 stops33h 20m
Multiple Airlines
Mon 3/239:05 pm
SCL
-
ORD
2 stops23h 26m
Multiple Airlines
Deal found 2/10$514
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:36 pm
ORD
-
SCL
2 stops52h 33m
Multiple Airlines
Mon 4/611:00 pm
SCL
-
ORD
1 stop35h 50m
Multiple Airlines
Deal found 2/10$521
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/307:56 am
ORD
-
SCL
1 stop13h 43m
Multiple Airlines
Sun 4/128:20 pm
SCL
-
ORD
2 stops38h 30m
Multiple Airlines
Deal found 2/10$526
This Copa Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:06 am
ORD
-
SCL
1 stop13h 37m
Copa Airlines
Tue 5/264:41 am
SCL
-
ORD
1 stop21h 34m
Copa Airlines
Deal found 2/10$528
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1312:20 pm
ORD
-
SCL
1 stop17h 45m
American Airlines
Wed 4/228:35 pm
SCL
-
ORD
1 stop15h 29m
American Airlines
Deal found 2/10$529
This Copa Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:06 am
ORD
-
SCL
1 stop17h 54m
Copa Airlines
Sun 5/32:22 am
SCL
-
ORD
1 stop23h 53m
Copa Airlines
Deal found 2/8$533
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:15 pm
ORD
-
SCL
2 stops33h 15m
Multiple Airlines
Tue 5/2611:00 pm
SCL
-
ORD
1 stop20h 15m
Multiple Airlines
Deal found 2/10$534
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:34 pm
ORD
-
SCL
2 stops25h 31m
Multiple Airlines
Sun 5/2410:55 pm
SCL
-
ORD
1 stop19h 40m
Multiple Airlines
Deal found 2/10$536
This Avianca deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:20 pm
ORD
-
SCL
1 stop13h 55m
Avianca
Fri 4/246:40 am
SCL
-
ORD
1 stop15h 40m
Avianca
Deal found 2/9$537
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:52 pm
ORD
-
SCL
2 stops28h 13m
Multiple Airlines
Fri 5/2911:00 pm
SCL
-
ORD
1 stop20h 15m
Multiple Airlines
Deal found 2/10$538
This Copa Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/178:34 am
ORD
-
SCL
1 stop13h 15m
Copa Airlines
Mon 3/2312:28 pm
SCL
-
ORD
1 stop14h 36m
Copa Airlines
Deal found 2/8$539
This LATAM Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:53 pm
MDW
-
SCL
2 stops17h 02m
LATAM Airlines
Sat 5/168:40 pm
SCL
-
MDW
1 stop14h 11m
LATAM Airlines
Deal found 2/8$544

Find flight deals from Indiana to Santiago

Keep the following information in mind while searching for Indiana to Santiago flight deals. Data was last updated February 11, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$514
(Mytrip)

One-way from

$205
(Kiwi.com)

Popular in

February

Cheapest in

March

Average price

$1,586
Provider with most accurate pricing for Indianapolis-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Santiago Arturo Merino Benitez flights.
Search Deals
From Indiana to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Indiana to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($84 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($44 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Indiana to Santiago that are best for you.

Fly from

Indiana

Fly to

Santiago

Route

Depart

Return

Price

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 4/13

8:06 am-10:43 pm

1 stop13h 37m

Santiago Arturo Merino Benitez

Wed 4/22

11:25 am-1:13 am

1 stop14h 48m

$517

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 4/27

8:06 am-11:26 pm

1 stop14h 20m

Santiago Arturo Merino Benitez

Mon 5/4

11:17 am-1:15 am

1 stop14h 58m

$517

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Fri 5/15

8:02 am-11:26 pm

1 stop14h 24m

Santiago Arturo Merino Benitez

Sun 5/24

2:22 am-1:15 am

1 stop23h 53m

$528

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 4/19

8:06 am-11:26 pm

1 stop14h 20m

Santiago Arturo Merino Benitez

Fri 4/24

11:25 am-1:13 am

1 stop14h 48m

$533

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Tue 3/17

8:34 am-11:49 pm

1 stop13h 15m

Santiago Arturo Merino Benitez

Mon 3/23

12:28 pm-1:04 am

1 stop14h 36m

$539

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Tue 3/10

1:37 pm-5:55 am

1 stop14h 18m

Santiago Arturo Merino Benitez

Tue 3/17

10:40 pm-12:57 pm

1 stop16h 17m

$540

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Tue 4/28

5:21 pm-7:15 am

1 stop12h 54m

Santiago Arturo Merino Benitez

Thu 5/28

8:40 pm-12:42 pm

2 stops17h 02m

$545

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Thu 4/30

1:23 pm-7:15 am

2 stops16h 52m

Santiago Arturo Merino Benitez

Tue 5/26

8:40 pm-9:51 am

1 stop14h 11m

$545

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Mon 4/27

5:21 pm-7:15 am

1 stop12h 54m

Santiago Arturo Merino Benitez

Thu 5/28

8:40 pm-11:56 am

1 stop16h 16m

$545

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Wed 4/29

5:21 pm-7:15 am

1 stop12h 54m

Santiago Arturo Merino Benitez

Tue 5/26

8:40 pm-12:42 pm

2 stops17h 02m

$545

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/10

Showing 1-10 of 53 results
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Best time to book a flight from Indiana to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Santiago

What is the cheapest month to book a flight from Indiana to Santiago?

Currently, November is the cheapest month in which you can book a flight from Indiana to Santiago (average of $718). Flying from Indiana to Santiago in February is currently the most expensive (average of $1,449). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Indiana to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Indiana?

    If you book a flight to Santiago from Indiana, you will be flying to Arturo Merino Benitez, which is the city’s only airport. Santiago Arturo Merino Benitez (SCL) is located 8.4 mi from the center of Santiago.

  • How long is the flight from Indiana to Santiago?

    There are many flights that can get you from Indiana to Santiago in 12h 54m. Fly via Copa Airlines, Delta, or LATAM Airlines to get the fastest option. The distance between Indiana and Santiago is about 5301 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Indiana to Santiago?

    Most travelers choose Chicago O'Hare Intl - Santiago Arturo Merino Benitez, Chicago Midway - Santiago Arturo Merino Benitez or Cincinnati Cinci./N. Kentucky - Santiago Arturo Merino Benitez when deciding on the best route from Indiana to Santiago.

  • Can I find deals for flights from Indiana to Santiago that include hotel bookings?

    Yes. In addition to deals on Indiana to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Santiago.

  • Can I find deals for business class flights from Indiana to Santiago?

    Yes. Cheapflights offers flight deals from Indiana to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Santiago?

    Currently, November is the cheapest month in which you can book a flight from Indiana to Santiago (average of $718). Flying from Indiana to Santiago in February is currently the most expensive (average of $1,449). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indiana to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Indiana to Santiago

Discover the top 3 airlines that operate flights from Indiana to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$803Average$1,023FlexibilityNo cancel feeOn-time81%
DeltaCheapest$844Average$1,063FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$864Average$1,164FlexibilityNo cancel feeOn-time71%

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