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$262+ Cheap flights from Indiana to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
IND — SCL
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Indiana to Santiago

Keep the following information in mind while searching for Indiana to Santiago flight deals. Data was last updated September 15, 2025.

Round-trip from

$603
(Mytrip)

One-way from

$262
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$953
From Indiana to Santiago Arturo Merino Benitez
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One-way flight from Indiana to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 6% potential increase in price ($62 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($32 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Indiana to Santiago

Cheapest flights from Indiana to Santiago
Explore the most affordable flight options available from Indiana to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Mytrip deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2610:27 amORD - SCL
2 stops26h 18mMultiple Airlines
Mon 9/295:55 amSCL - ORD
3 stops29h 23mMultiple Airlines
Deal found 9/12$602
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:49 amIND - SCL
2 stops19h 46mMultiple Airlines
Fri 2/279:10 pmSCL - IND
3 stops29h 22mMultiple Airlines
Deal found 9/15$603
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/107:30 pmORD - SCL
3 stops29h 05mMultiple Airlines
Sun 11/1612:30 pmSCL - ORD
2 stops27h 00mMultiple Airlines
Deal found 9/14$604
This Avianca Connect deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3010:43 amIND - SCL
2 stops17h 47mMultiple Airlines
Wed 11/51:35 amSCL - IND
2 stops23h 21mMultiple Airlines
Deal found 9/15$607
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2911:08 amORD - SCL
3 stops33h 07mMultiple Airlines
Wed 11/55:50 amSCL - ORD
2 stops33h 40mMultiple Airlines
Deal found 9/14$610
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3010:27 amORD - SCL
2 stops33h 48mMultiple Airlines
Thu 11/611:25 pmSCL - ORD
1 stop16h 05mMultiple Airlines
Deal found 9/15$611
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/101:35 pmORD - SCL
2 stops35h 00mMultiple Airlines
Wed 11/1911:25 pmSCL - ORD
1 stop16h 05mMultiple Airlines
Deal found 9/14$618
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/162:35 pmORD - SCL
1 stop21h 50mAvianca
Tue 9/303:30 pmSCL - ORD
1 stop23h 45mAvianca
Deal found 9/15$620
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/91:35 pmORD - SCL
2 stops29h 40mMultiple Airlines
Sun 11/1610:50 amSCL - ORD
1 stop28h 40mMultiple Airlines
Deal found 9/14$621
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/410:20 pmORD - SCL
1 stop14h 00mMultiple Airlines
Tue 11/184:25 pmSCL - ORD
2 stops48h 13mMultiple Airlines
Deal found 9/14$623
This Trip.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:15 amSDF - SCL
2 stops22h 20mMultiple Airlines
Wed 11/54:35 amSCL - SDF
2 stops21h 10mMultiple Airlines
Deal found 9/15$685
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/196:40 pmIND - SCL
3 stops43h 05mMultiple Airlines
Sun 11/23:33 pmSCL - IND
3 stops20h 15mMultiple Airlines
Deal found 9/14$711

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Indiana to Santiago that are best for you.

Fly from

Indiana

Fly to

Santiago

Route

Depart

Return

Price

IndianapolisSantiago

IND - SCL

INDSCL

Indianapolis

Thu 10/30

10:43 am-5:30 am

2 stops17h 47m

Santiago Arturo Merino Benitez

Wed 11/5

1:35 am-10:56 pm

2 stops23h 21m

$607

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Tue 11/4

4:03 pm-5:50 am

3 stops34h 47m

Santiago Arturo Merino Benitez

Tue 11/18

12:30 pm-7:16 pm

3 stops33h 46m

$648

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 10/6

2:35 pm-5:15 am

1 stop12h 40m

Santiago Arturo Merino Benitez

Mon 10/20

12:55 am-1:15 pm

1 stop14h 20m

$653

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Tue 11/4

10:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

Sun 11/9

1:35 am-8:20 pm

1 stop21h 45m

$663

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sat 11/15

8:00 am-5:30 am

2 stops18h 30m

Santiago Arturo Merino Benitez

Tue 11/18

11:25 pm-12:30 pm

1 stop16h 05m

$664

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 10/6

7:59 am-11:40 pm

1 stop13h 41m

Santiago Arturo Merino Benitez

Tue 10/21

12:29 pm-12:21 am

1 stop13h 52m

$672

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Tue 11/4

6:56 am-11:41 pm

1 stop13h 45m

Santiago Arturo Merino Benitez

Mon 11/17

3:23 am-12:05 am

1 stop23h 42m

$672

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Wed 11/12

6:56 am-3:43 am

1 stop17h 47m

Santiago Arturo Merino Benitez

Thu 11/20

5:12 am-12:05 am

1 stop21h 53m

$672

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 10/13

7:59 am-12:04 am

1 stop14h 05m

Santiago Arturo Merino Benitez

Mon 10/20

4:47 am-12:21 am

1 stop21h 34m

$672

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 10/30

7:59 am-3:42 am

1 stop17h 43m

Santiago Arturo Merino Benitez

Wed 11/5

1:12 am-12:46 pm

1 stop14h 34m

$672

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 49 results
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Best time to book a flight from Indiana to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Santiago

What is the cheapest month to book a flight from Indiana to Santiago?

Currently, April is the cheapest month in which you can book a flight from Indiana to Santiago (average of $752). Flying from Indiana to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to SCL?

Find hourly flight availability from Indiana to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from Indiana to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from Indiana to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Indiana?

    If you book a flight to Santiago from Indiana, you will be flying to Arturo Merino Benitez, which is the city’s only airport. Santiago Arturo Merino Benitez (SCL) is located 8.4 mi from the center of Santiago.

  • How long is the flight from Indiana to Santiago?

    There are many flights that can get you from Indiana to Santiago in 12h 20m. Fly via Avianca, Copa Airlines, or LATAM Airlines to get the fastest option. The distance between Indiana and Santiago is about 5080 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Indiana to Santiago?

    Most travelers choose Chicago O'Hare Intl - Santiago Arturo Merino Benitez, Chicago Midway - Santiago Arturo Merino Benitez or Indianapolis - Santiago Arturo Merino Benitez when deciding on the best route from Indiana to Santiago.

  • Can I find deals for flights from Indiana to Santiago that include hotel bookings?

    Yes. In addition to deals on Indiana to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Santiago.

  • Can I find deals for business class flights from Indiana to Santiago?

    Yes. Cheapflights offers flight deals from Indiana to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Indiana to Santiago (average of $752). Flying from Indiana to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indiana to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Indiana to Santiago

Discover the top 2 airlines that operate flights from Indiana to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$693Average$1,005FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$803Average$970FlexibilityNo cancel feeOn-time81%

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