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$368+ Cheap flights from Buffalo (BUF) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/5. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — SCL
Apr 27 — May 41
Sun 4/27
Sun 5/4
1 adult, Economy
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Cheap flight deals from Buffalo to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 22, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$1,058
(American Airlines)

One-way from

$368
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$803
Provider with most accurate pricing for Buffalo-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Santiago Arturo Merino Benitez flights.
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From Buffalo to Santiago Arturo Merino Benitez
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One-way flight from Buffalo to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 6% potential increase in price ($74 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($38 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Buffalo to Santiago

Cheapest flights from Buffalo to Santiago
Explore the most affordable flight options available from Buffalo to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/212:25 pmBUF - SCL
2 stops16h 30mAmerican Airlines
Wed 6/119:55 pmSCL - BUF
2 stops19h 19mAmerican Airlines
Deal found 4/21$1,058
This FlightHub deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2312:10 pmBUF - SCL
2 stops16h 35mLATAM Airlines
Thu 7/248:40 pmSCL - BUF
1 stop14h 36mLATAM Airlines
Deal found 4/20$1,071
This Copa Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/106:15 amBUF - SCL
2 stops22h 49mCopa Airlines
Thu 6/1212:13 amSCL - BUF
2 stops20h 48mCopa Airlines
Deal found 4/22$1,076
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/206:00 amBUF - SCL
2 stops15h 55mDelta
Mon 5/2612:30 amSCL - BUF
2 stops23h 25mDelta
Deal found 4/21$1,104
This LATAM Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2010:33 amBUF - SCL
1 stop20h 12mMultiple Airlines
Mon 5/2612:30 amSCL - BUF
2 stops41h 00mMultiple Airlines
Deal found 4/21$1,106

Cheapflights Fare Finder

Customize your flight search to find flights from Buffalo to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
Use the filters below to find and compare flights from Buffalo to Santiago that are best for you.

Fly from

Buffalo

Fly to

Santiago

Route

Depart

Return

Price

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Wed 5/21

2:25 pm-6:55 am

2 stops16h 30m

Santiago Arturo Merino Benitez

Wed 6/11

9:55 pm-5:14 pm

2 stops19h 19m

$1,058

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Mon 6/23

12:10 pm-4:45 am

2 stops16h 35m

Santiago Arturo Merino Benitez

Thu 7/24

8:40 pm-11:16 am

1 stop14h 36m

$1,071

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Tue 6/10

6:15 am-5:04 am

2 stops22h 49m

Santiago Arturo Merino Benitez

Thu 6/12

12:13 am-9:01 pm

2 stops20h 48m

$1,076

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Tue 5/20

6:35 pm-2:00 pm

2 stops19h 25m

Santiago Arturo Merino Benitez

Tue 5/27

10:35 am-11:00 am

2 stops24h 25m

$1,104

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Tue 5/20

10:33 am-6:45 am

1 stop20h 12m

Santiago Arturo Merino Benitez

Mon 5/26

12:30 am-5:30 pm

2 stops41h 00m

$1,106

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Thu 6/5

9:37 pm-12:50 am

2 stops27h 13m

$368

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Wed 5/21

12:05 pm-5:50 am

2 stops17h 45m

$543

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Sun 8/10

12:09 pm-7:00 am

1 stop18h 51m

$583

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Compare providers for flights from Buffalo to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Santiago in April.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Santiago flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Buffalo-Santiago flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Buffalo-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Santiago flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Santiago

What is the cheapest time of day to fly from BUF to SCL?

Find hourly flight availability from Buffalo to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

When flying from Buffalo to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 7% versus a flight at noon.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 22, 2025.
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
LATAM Airlines
7.5
Good
1,764 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Copa Airlines
7.5
Good
1,408 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Buffalo to Santiago round-trip?

    Flying on American Airlines is currently your cheapest option to Santiago, with prices starting at $1,058. Additional round-trip tickets that might be worth considering are offered by LATAM Airlines and Copa Airlines, with the lowest prices starting at $1,071 and $1,076, respectively.

  • Can I find deals for flights from Buffalo to Santiago that include hotel bookings?

    Yes. In addition to deals on Buffalo to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Santiago.

  • Can I find deals for business class flights from Buffalo to Santiago?

    Yes. Cheapflights offers flight deals from Buffalo to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Buffalo to Santiago (average of $752). Flying from Buffalo to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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