$252+ Cheap flights from South America to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
BOG — SFO
Jan 17 — Jan 241
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South America to San Francisco
Cheapest flights from South America to San FranciscoExplore the most affordable flight options available from South America to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.
Explore the most affordable flight options available from South America to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.
This Copa Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:24 amMDE - SFO
1 stop19h 53mCopa Airlines
Thu 1/2912:42 amSFO - MDE
1 stop16h 53mCopa Airlines
Deal found 12/17![Copa Airlines logo]()
$435
This Copa Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2012:42 pmMDE - SFO
1 stop13h 35mCopa Airlines
Tue 12/3012:36 amSFO - MDE
1 stop16h 40mCopa Airlines
Deal found 12/16![Copa Airlines logo]()
$437
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1910:45 amMDE - SFO
1 stop16h 36mUnited Airlines
Fri 1/25:15 amSFO - MDE
1 stop21h 27mUnited Airlines
Deal found 12/16![United Airlines logo]()
$442
This Avianca deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2410:40 amMDE - SFO
2 stops14h 10mAvianca
Fri 1/3011:10 pmSFO - MDE
1 stop10h 45mAvianca
Deal found 12/16![Avianca logo]()
$444
This Cheapflightsfares deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/234:00 amBOG - SFO
1 stop11h 00mAvianca
Thu 1/81:35 amSFO - BOG
1 stop11h 25mAvianca
Deal found 12/16![Avianca logo]()
$484
This Cheapflightsfares deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:30 pmBOG - SFO
1 stop12h 50mAvianca
Thu 1/81:20 pmSFO - BOG
1 stop9h 30mAvianca
Deal found 12/17![Avianca logo]()
$486
This Flightnetwork deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:00 amBOG - SFO
1 stop19h 17mCopa Airlines
Thu 1/2912:42 amSFO - BOG
1 stop20h 38mCopa Airlines
Deal found 12/17![Copa Airlines logo]()
$503
This Copa Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2110:40 amBOG - SFO
1 stop15h 37mCopa Airlines
Sat 1/1712:42 amSFO - BOG
1 stop9h 47mCopa Airlines
Deal found 12/16![Copa Airlines logo]()
$506
This Copa Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2210:00 amBOG - SFO
1 stop16h 17mCopa Airlines
Thu 2/1912:42 amSFO - BOG
1 stop19h 13mCopa Airlines
Deal found 12/15![Copa Airlines logo]()
$507
This Avianca deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:30 pmBOG - SFO
1 stop11h 20mAvianca
Thu 1/81:35 amSFO - BOG
1 stop11h 25mAvianca
Deal found 12/16![Avianca logo]()
$508
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/188:15 amBOG - SFO
1 stop17h 34mUnited Airlines
Tue 12/307:11 pmSFO - BOG
1 stop24h 24mUnited Airlines
Deal found 12/15![United Airlines logo]()
$509
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/183:55 pmBOG - SFO
1 stop21h 35mDelta
Wed 12/312:05 pmSFO - BOG
2 stops17h 50mDelta
Deal found 12/16![Delta logo]()
$510
Find flight deals from South America to San Francisco
Keep the following information in mind while searching for South America to San Francisco flight deals. Data was last updated December 18, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $421 (Cheapflightsfares) |
One-way from | $252 (Kiwi.com) |
Popular in | July |
Cheapest in | February |
Average price | $896 |
Cheapflights Fare Finder
Customize your flight search to find flights from South America to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from South America to San Francisco that are best for you.
Fly from
South America
Fly to
San Francisco
Route
Depart
Return
Price
MedellínSan Francisco
MDE - SFO
MDESFO
Medellín Jose Maria Cordova Intl
Wed 1/28
10:15 pm-12:00 pm
2 stops16h 45m
San Francisco
Wed 2/4
11:10 pm-12:55 pm
1 stop10h 45m
$421
MedellínSan Francisco
MDE - SFO
MDESFO
Medellín Jose Maria Cordova Intl
Wed 1/21
12:42 pm-11:20 pm
1 stop13h 38m
San Francisco
Fri 3/13
1:54 am-2:15 pm
1 stop10h 21m
$435
MedellínSan Francisco
MDE - SFO
MDESFO
Medellín Jose Maria Cordova Intl
Mon 2/2
8:37 am-11:20 pm
1 stop17h 43m
San Francisco
Tue 2/10
12:42 am-2:45 pm
1 stop11h 03m
$435
MedellínSan Francisco
MDE - SFO
MDESFO
Medellín Jose Maria Cordova Intl
Sat 1/31
9:17 am-11:20 pm
1 stop17h 03m
San Francisco
Fri 2/6
12:42 am-2:15 pm
1 stop10h 33m
$435
MedellínSan Francisco
MDE - SFO
MDESFO
Medellín Jose Maria Cordova Intl
Sat 3/14
5:00 am-11:40 pm
1 stop20h 40m
San Francisco
Sat 3/14
1:54 am-2:15 pm
1 stop10h 21m
$435
MedellínSan Francisco
MDE - SFO
MDESFO
Medellín Jose Maria Cordova Intl
Wed 3/25
2:10 pm-10:50 pm
1 stop10h 40m
San Francisco
Wed 4/15
2:20 pm-2:05 am
1 stop9h 45m
$436
MedellínSan Francisco
MDE - SFO
MDESFO
Medellín Jose Maria Cordova Intl
Wed 3/25
10:46 am-11:40 pm
1 stop14h 54m
San Francisco
Sun 4/5
8:35 pm-2:45 pm
1 stop16h 10m
$437
MedellínSan Francisco
MDE - SFO
MDESFO
Medellín Jose Maria Cordova Intl
Fri 5/1
9:45 am-10:39 am
1 stop26h 54m
San Francisco
Tue 5/5
5:00 am-9:10 pm
1 stop14h 10m
$438
BogotáSan Francisco
BOG - SFO
BOGSFO
Bogotá El Dorado
Tue 2/3
8:40 am-11:20 pm
1 stop17h 40m
San Francisco
Tue 2/10
12:42 am-1:29 pm
1 stop9h 47m
$506
BogotáSan Francisco
BOG - SFO
BOGSFO
Bogotá El Dorado
Sun 12/21
10:40 am-11:17 pm
1 stop15h 37m
San Francisco
Sat 1/17
12:42 am-1:29 pm
1 stop9h 47m
$506
Showing 1-10 of 60 results
Best time to book a flight from South America to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from South America with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South America to San Francisco
What is the cheapest month to book a flight from South America to San Francisco?
Currently, September is the cheapest month in which you can book a flight from South America to San Francisco (average of $221). Flying from South America to San Francisco in January is currently the most expensive (average of $351). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SA to SFO?
Find hourly flight availability from South America to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.
One of the essential ways to save on airfare from South America to San Francisco is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 13% on airfare.
What is the cheapest day to fly from South America to San Francisco?
Use this chart to determine the cheapest time to fly round-trip from South America to San Francisco. Price data was last updated on December 16, 2024.
Travelers seeking maximum savings on their South America to San Francisco flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated December 18, 2025.
Read through reviews of airlines operating flights from South America to San Francisco, such as Copa Airlines, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.6
Crew
8.1
Comfort
7.4
Entertainment
6.8
Food
6.8
Boarding
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Sep 2025
PEI - PTY
Overall
7.6
Crew
8.1
Comfort
7.4
Entertainment
6.8
Food
6.8
Boarding
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Sep 2025
PEI - PTY
Overall
7.6
Crew
8.1
Comfort
7.4
Entertainment
6.8
Food
6.8
Boarding
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Sep 2025
PEI - PTY
Overall
7.6
Crew
8.1
Comfort
7.4
Entertainment
6.8
Food
6.8
Boarding
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Sep 2025
PEI - PTY
Overall
7.6
Crew
8.1
Comfort
7.4
Entertainment
6.8
Food
6.8
Boarding
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Sep 2025
PEI - PTY
Overall
7.6
Crew
8.1
Comfort
7.4
Entertainment
6.8
Food
6.8
Boarding
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Sep 2025
PEI - PTY
Related info for your journey
Find useful and relevant information for your journey from South America to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsRoseville
South San Francisco
Santa Cruz
Livermore
Turlock
Manteca
Watsonville
Redwood City
Sunnyvale
Santa Clara
San Bruno
Daly City
San Carlos
Vallejo
Hollister
San Ramon
Foster City
Union City
Davis
Emeryville
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Alternative routes for South America to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Top 9 airlines flying from South America to San Francisco
Discover the top 9 airlines that operate flights from South America to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$276 | Average$761 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$288 | Average$715 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$344 | Average$627 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$359 | Average$805 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$440 | Average$852 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$481 | Average$830 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$527 | Average$615 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$569 | Average$635 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$832 | Average$903 | FlexibilityNo cancel fee | On-time74% |