$216+ Cheap flights from South America to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
BOG — SFO
Apr 9 — Apr 161
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from South America to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South America to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from South America to San FranciscoExplore the most affordable flight options available from South America to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
Explore the most affordable flight options available from South America to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:30 am
BOG
- SFO
1 stop18h 31m
American Airlines
Wed 4/291:12 pm
SFO
- BOG
1 stop21h 53m
American Airlines
Deal found 3/6![American Airlines logo]()
$342
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:30 am
BOG
- SFO
1 stop18h 31m
American Airlines
Wed 5/65:32 am
SFO
- BOG
1 stop14h 58m
American Airlines
Deal found 3/6![American Airlines logo]()
$346
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:30 am
BOG
- SFO
1 stop19h 29m
American Airlines
Thu 5/285:23 am
SFO
- BOG
1 stop15h 15m
American Airlines
Deal found 3/8![American Airlines logo]()
$347
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:30 am
BOG
- SFO
2 stops16h 34m
American Airlines
Tue 4/286:15 am
SFO
- BOG
1 stop13h 02m
American Airlines
Deal found 3/9![American Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:00 am
MDE
- SFO
2 stops19h 59m
American Airlines
Tue 4/2812:30 am
SFO
- MDE
2 stops17h 45m
American Airlines
Deal found 3/8![American Airlines logo]()
$353
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:25 am
BOG
- SFO
1 stop24h 34m
American Airlines
Sat 5/96:15 am
SFO
- BOG
1 stop13h 02m
American Airlines
Deal found 3/7![American Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:25 am
BOG
- SFO
1 stop16h 34m
American Airlines
Tue 5/127:10 am
SFO
- BOG
2 stops13h 20m
American Airlines
Deal found 3/5![American Airlines logo]()
$356
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:25 am
BOG
- SFO
1 stop20h 50m
American Airlines
Fri 5/111:49 pm
SFO
- BOG
1 stop20h 41m
American Airlines
Deal found 3/10![American Airlines logo]()
$367
This Avianca deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/141:40 pm
BOG
- SFO
1 stop12h 15m
Avianca
Sat 5/162:15 pm
SFO
- BOG
1 stop9h 45m
Avianca
Deal found 3/5![Avianca logo]()
$368
This Avianca deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:40 pm
BOG
- SFO
1 stop12h 15m
Avianca
Thu 4/232:15 pm
SFO
- BOG
1 stop9h 45m
Avianca
Deal found 3/7![Avianca logo]()
$369
This Avianca deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:40 pm
BOG
- SFO
1 stop12h 15m
Avianca
Sat 4/2511:55 pm
SFO
- BOG
1 stop10h 05m
Avianca
Deal found 3/9![Avianca logo]()
$370
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:00 am
MDE
- SFO
1 stop19h 59m
American Airlines
Sun 5/310:30 pm
SFO
- MDE
1 stop12h 18m
American Airlines
Deal found 3/9![American Airlines logo]()
$370
Best flights from South America to San FranciscoDiscover carefully curated flight deals from South America to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
Discover carefully curated flight deals from South America to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/288:30 am
BOG
- SFO
1 stop12h 28m
United Airlines
Tue 5/122:28 pm
SFO
- BOG
1 stop26h 52m
United Airlines
Deal found 3/7![United Airlines logo]()
$371
This Avianca deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:10 pm
MDE
- SFO
1 stop11h 45m
Avianca
Sat 5/211:55 pm
SFO
- MDE
1 stop11h 15m
Avianca
Deal found 3/6![Avianca logo]()
$373
This Copa Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:40 pm
MDE
- SFO
1 stop13h 00m
Copa Airlines
Sun 8/301:12 am
SFO
- MDE
1 stop11h 33m
Copa Airlines
Deal found 3/6![Copa Airlines logo]()
$464
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:59 am
UIO
- SFO
1 stop21h 25m
Delta
Mon 5/115:50 am
SFO
- UIO
2 stops20h 53m
Delta
Deal found 3/5![Delta logo]()
$466
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:45 am
MDE
- SFO
1 stop23h 30m
United Airlines
Sun 5/107:15 am
SFO
- MDE
1 stop11h 55m
United Airlines
Deal found 3/5![United Airlines logo]()
$372
This LATAM Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/248:45 am
LIM
- SFO
1 stop30h 14m
Multiple Airlines
Mon 3/3010:35 pm
SFO
- LIM
1 stop21h 20m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$760
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:45 am
MDE
- SFO
1 stop11h 20m
United Airlines
Wed 5/1312:45 am
SFO
- MDE
1 stop18h 25m
United Airlines
Deal found 3/5![United Airlines logo]()
$372
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/299:45 am
MDE
- SFO
1 stop28h 33m
United Airlines
Fri 5/1511:59 pm
SFO
- MDE
1 stop19h 11m
United Airlines
Deal found 3/7![United Airlines logo]()
$374
This Copa Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:01 am
UIO
- SFO
1 stop19h 39m
Copa Airlines
Wed 4/298:37 pm
SFO
- UIO
1 stop18h 55m
Copa Airlines
Deal found 3/7![Copa Airlines logo]()
$477
This GOL deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:15 pm
GIG
- SFO
2 stops31h 44m
GOL
Wed 6/39:50 pm
SFO
- GIG
1 stop30h 30m
GOL
Deal found 3/6![GOL logo]()
$990
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:45 am
MDE
- SFO
1 stop28h 33m
United Airlines
Mon 4/2011:59 pm
SFO
- MDE
1 stop19h 11m
United Airlines
Deal found 3/7![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:35 pm
EZE
- SFO
2 stops19h 50m
American Airlines
Tue 4/2110:46 am
SFO
- EZE
1 stop20h 19m
American Airlines
Deal found 3/10![American Airlines logo]()
$1,031
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/243:55 pm
BOG
- SFO
2 stops24h 51m
Delta
Fri 5/19:35 pm
SFO
- BOG
1 stop19h 40m
Delta
Deal found 3/6![Delta logo]()
$516
This Copa Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/32:29 pm
UIO
- SFO
1 stop11h 11m
Copa Airlines
Sun 5/101:12 am
SFO
- UIO
1 stop17h 31m
Copa Airlines
Deal found 3/7![Copa Airlines logo]()
$501
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:40 am
BOG
- SFO
2 stops18h 43m
Delta
Fri 5/811:59 pm
SFO
- BOG
2 stops18h 11m
Delta
Deal found 3/6![Delta logo]()
$516
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/288:30 am
BOG
- SFO
1 stop16h 00m
United Airlines
Wed 5/138:55 am
SFO
- BOG
1 stop17h 59m
United Airlines
Deal found 3/9![United Airlines logo]()
$398
This Copa Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/232:30 pm
UIO
- SFO
1 stop11h 10m
Copa Airlines
Thu 4/308:37 pm
SFO
- UIO
1 stop18h 55m
Copa Airlines
Deal found 3/6![Copa Airlines logo]()
$515
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/229:45 am
MDE
- SFO
1 stop11h 13m
United Airlines
Wed 5/62:28 pm
SFO
- MDE
1 stop28h 42m
United Airlines
Deal found 3/9![United Airlines logo]()
$400
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/239:45 am
MDE
- SFO
1 stop26h 55m
United Airlines
Mon 5/412:45 am
SFO
- MDE
1 stop18h 25m
United Airlines
Deal found 3/9![United Airlines logo]()
$400
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:55 pm
SCL
- SFO
1 stop22h 54m
Delta
Thu 8/207:00 am
SFO
- SCL
1 stop19h 35m
Delta
Deal found 3/9![Delta logo]()
$611
This eDestinos deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:30 pm
LIM
- SFO
2 stops26h 06m
Multiple Airlines
Sun 5/3110:24 pm
SFO
- LIM
3 stops52h 37m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$761
This Copa Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:17 am
SCL
- SFO
1 stop15h 23m
Copa Airlines
Mon 5/181:12 am
SFO
- SCL
1 stop15h 11m
Copa Airlines
Deal found 3/6![Copa Airlines logo]()
$573
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:30 am
BOG
- SFO
1 stop12h 35m
United Airlines
Wed 5/611:59 pm
SFO
- BOG
1 stop17h 21m
United Airlines
Deal found 3/9![United Airlines logo]()
$415
This Avianca deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:20 am
GIG
- SFO
2 stops44h 35m
Avianca
Tue 5/2611:55 pm
SFO
- GIG
2 stops20h 35m
Avianca
Deal found 3/10![Avianca logo]()
$814
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2110:55 pm
SCL
- SFO
1 stop27h 17m
Delta
Mon 5/411:00 am
SFO
- SCL
1 stop15h 35m
Delta
Deal found 3/9![Delta logo]()
$626
This Copa Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2411:25 am
SCL
- SFO
1 stop15h 15m
Copa Airlines
Sun 5/101:12 am
SFO
- SCL
1 stop19h 14m
Copa Airlines
Deal found 3/10![Copa Airlines logo]()
$573
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:45 am
MDE
- SFO
1 stop16h 30m
United Airlines
Tue 6/25:00 am
SFO
- MDE
1 stop14h 10m
United Airlines
Deal found 3/5![United Airlines logo]()
$418
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:40 am
SCL
- SFO
2 stops21h 44m
Delta
Tue 8/187:00 am
SFO
- SCL
1 stop19h 35m
Delta
Deal found 3/6![Delta logo]()
$646
This Copa Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:49 am
SCL
- SFO
1 stop16h 36m
Copa Airlines
Thu 4/238:37 pm
SFO
- SCL
1 stop19h 46m
Copa Airlines
Deal found 3/5![Copa Airlines logo]()
$593
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/279:45 am
MDE
- SFO
1 stop16h 30m
United Airlines
Tue 6/25:00 am
SFO
- MDE
1 stop14h 10m
United Airlines
Deal found 3/5![United Airlines logo]()
$418
Last-minute flights from South America to San FranciscoDiscover last-minute flight deals from South America to San Francisco. Data last updated March 10, 2026 and is based on user searches.
Discover last-minute flight deals from South America to San Francisco. Data last updated March 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:30 am
BOG
- SFO
1 stop18h 31m
American Airlines
Wed 4/291:12 pm
SFO
- BOG
1 stop21h 53m
American Airlines
Deal found 3/6![American Airlines logo]()
$342
This Avianca deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:40 pm
BOG
- SFO
1 stop12h 15m
Avianca
Sat 5/22:30 am
SFO
- BOG
1 stop11h 30m
Avianca
Deal found 3/6![Avianca logo]()
$369
This Avianca deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:40 pm
BOG
- SFO
1 stop12h 15m
Avianca
Sat 4/2511:55 pm
SFO
- BOG
1 stop10h 05m
Avianca
Deal found 3/9![Avianca logo]()
$370
This Avianca deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:40 pm
BOG
- SFO
1 stop12h 15m
Avianca
Tue 4/2811:55 pm
SFO
- BOG
1 stop14h 05m
Avianca
Deal found 3/9![Avianca logo]()
$372
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:30 am
BOG
- SFO
2 stops16h 34m
American Airlines
Tue 4/286:15 am
SFO
- BOG
1 stop13h 02m
American Airlines
Deal found 3/9![American Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:30 am
BOG
- SFO
1 stop18h 31m
American Airlines
Wed 5/65:32 am
SFO
- BOG
1 stop14h 58m
American Airlines
Deal found 3/6![American Airlines logo]()
$346
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:00 am
MDE
- SFO
2 stops19h 59m
American Airlines
Tue 4/2812:30 am
SFO
- MDE
2 stops17h 45m
American Airlines
Deal found 3/8![American Airlines logo]()
$353
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:25 am
BOG
- SFO
1 stop20h 50m
American Airlines
Fri 5/111:49 pm
SFO
- BOG
1 stop20h 41m
American Airlines
Deal found 3/10![American Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:00 am
MDE
- SFO
1 stop19h 59m
American Airlines
Sun 5/310:30 pm
SFO
- MDE
1 stop12h 18m
American Airlines
Deal found 3/9![American Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:25 am
BOG
- SFO
1 stop16h 34m
American Airlines
Tue 5/127:10 am
SFO
- BOG
2 stops13h 20m
American Airlines
Deal found 3/5![American Airlines logo]()
$356
This Avianca deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/301:40 pm
BOG
- SFO
1 stop12h 15m
Avianca
Thu 5/142:15 pm
SFO
- BOG
1 stop9h 45m
Avianca
Deal found 3/5![Avianca logo]()
$371
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:45 am
MDE
- SFO
1 stop16h 14m
United Airlines
Fri 5/154:45 pm
SFO
- MDE
1 stop26h 25m
United Airlines
Deal found 3/5![United Airlines logo]()
$372
One-way flights from South America to San FranciscoSearch for one-way flight options from South America to San Francisco. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
Search for one-way flight options from South America to San Francisco. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:53 pm
MDE
- SFO
1 stop12h 06m
American Airlines
Deal found 3/6![American Airlines logo]()
$216
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
MDE
- SFO
1 stop19h 59m
American Airlines
Deal found 3/6![American Airlines logo]()
$219
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:00 am
MDE
- SFO
1 stop19h 59m
American Airlines
Deal found 3/9![American Airlines logo]()
$228
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:25 am
BOG
- SFO
2 stops17h 00m
American Airlines
Deal found 3/9![American Airlines logo]()
$231
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
MDE
- SFO
2 stops19h 15m
American Airlines
Deal found 3/9![American Airlines logo]()
$233
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:25 am
BOG
- SFO
1 stop24h 44m
American Airlines
Deal found 3/9![American Airlines logo]()
$234
This Avianca deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:40 pm
BOG
- SFO
1 stop12h 15m
Avianca
Deal found 3/7![Avianca logo]()
$240
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:30 am
BOG
- SFO
1 stop24h 52m
United Airlines
Deal found 3/7![United Airlines logo]()
$244
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:45 am
MDE
- SFO
1 stop25h 57m
United Airlines
Deal found 3/7![United Airlines logo]()
$246
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:45 am
MDE
- SFO
1 stop23h 31m
United Airlines
Deal found 3/8![United Airlines logo]()
$247
This Avianca deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3010:40 am
MDE
- SFO
2 stops15h 15m
Avianca
Deal found 3/7![Avianca logo]()
$248
This Aviatur deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aviatur is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:10 pm
MDE
- SFO
1 stop11h 45m
Avianca
Deal found 3/5![Avianca logo]()
$251
Find flight deals from South America to San Francisco
Keep the following information in mind while searching for South America to San Francisco flight deals. Data was last updated March 10, 2026.
Round-trip from | $342 (American Airlines) |
|---|---|
One-way from | $216 (American Airlines) |
Popular in | December |
Cheapest in | February |
Average price | $530 |
Cheapflights Fare Finder
Customize your flight search to find flights from South America to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from South America to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BogotáSan Francisco
BOG - SFO
BOGSFO
Bogotá El Dorado
Tue 4/28
8:30 am-6:58 pm
1 stop12h 28m
San Francisco
Tue 5/12
2:28 pm-7:20 pm
1 stop26h 52m
$371
MedellínSan Francisco
MDE - SFO
MDESFO
Medellín Jose Maria Cordova Intl
Mon 5/4
9:45 am-7:15 am
1 stop23h 30m
San Francisco
Sun 5/10
7:15 am-9:10 pm
1 stop11h 55m
$372
MedellínSan Francisco
MDE - SFO
MDESFO
Medellín Jose Maria Cordova Intl
Thu 5/7
9:45 am-7:05 pm
1 stop11h 20m
San Francisco
Wed 5/13
12:45 am-9:10 pm
1 stop18h 25m
$372
Quickest round-trip
MedellínSan Francisco
MDE - SFO
MDESFO
Medellín Jose Maria Cordova Intl
Thu 4/16
2:10 pm-11:55 pm
1 stop11h 45m
San Francisco
Sat 5/2
11:55 pm-1:10 pm
1 stop11h 15m
$373
MedellínSan Francisco
MDE - SFO
MDESFO
Medellín Jose Maria Cordova Intl
Wed 4/29
9:45 am-12:18 pm
1 stop28h 33m
San Francisco
Fri 5/15
11:59 pm-9:10 pm
1 stop19h 11m
$374
MedellínSan Francisco
MDE - SFO
MDESFO
Medellín Jose Maria Cordova Intl
Thu 4/16
9:45 am-12:18 pm
1 stop28h 33m
San Francisco
Mon 4/20
11:59 pm-9:10 pm
1 stop19h 11m
$374
BogotáSan Francisco
BOG - SFO
BOGSFO
Bogotá El Dorado
Tue 4/28
8:30 am-10:30 pm
1 stop16h 00m
San Francisco
Wed 5/13
8:55 am-4:54 am
1 stop17h 59m
$398
MedellínSan Francisco
MDE - SFO
MDESFO
Medellín Jose Maria Cordova Intl
Wed 4/22
9:45 am-6:58 pm
1 stop11h 13m
San Francisco
Wed 5/6
2:28 pm-9:10 pm
1 stop28h 42m
$400
MedellínSan Francisco
MDE - SFO
MDESFO
Medellín Jose Maria Cordova Intl
Thu 4/23
9:45 am-10:40 am
1 stop26h 55m
San Francisco
Mon 5/4
12:45 am-9:10 pm
1 stop18h 25m
$400
BogotáSan Francisco
BOG - SFO
BOGSFO
Bogotá El Dorado
Tue 5/5
8:30 am-7:05 pm
1 stop12h 35m
San Francisco
Wed 5/6
11:59 pm-7:20 pm
1 stop17h 21m
$415
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South America to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from South America with our price prediction graph.
BOG-SFO
MDE-SFO
UIO-SFO
LIM-SFO
GIG-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South America to San Francisco
0SA-SFO
BOG-SFO
MDE-SFO
UIO-SFO
LIM-SFO
What is the cheapest month to book a flight from South America to San Francisco?
Currently, February is the cheapest month in which you can book a flight from South America to San Francisco (average of $222). Flying from South America to San Francisco in July is currently the most expensive (average of $315). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated March 10, 2026.
Read through reviews of airlines operating flights from South America to San Francisco, such as Copa Airlines,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.4
Food
6.8
Boarding
7.8
Entertainment
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Comfort
7.4
Food
6.8
Boarding
7.8
Entertainment
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Comfort
7.4
Food
6.8
Boarding
7.8
Entertainment
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Comfort
7.4
Food
6.8
Boarding
7.8
Entertainment
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Comfort
7.4
Food
6.8
Boarding
7.8
Entertainment
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Comfort
7.4
Food
6.8
Boarding
7.8
Entertainment
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Related info for your journey
Find useful and relevant information for your journey from South America to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Livermore
Roseville
Watsonville
San Bruno
Sunnyvale
Vacaville
Turlock
San Carlos
San Ramon
Redwood City
Daly City
Rancho Cordova
San Lorenzo
Davis
Hollister
Manteca
Union City
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
San Francisco flight routes
Top destinations
Alternative routes for South America to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South America to San Francisco by cabin class
Find flights from South America to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South America and San Francisco flights
Browse other South America and San Francisco flight options. Last updated on March 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 10, 2026.
South America to San Francisco flights
Consider these flights traveling from South America to San Francisco.
Top 9 airlines flying from South America to San Francisco
Discover the top 9 airlines that operate flights from South America to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$208 | Average$610 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$230 | Average$699 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$263 | Average$739 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$330 | Average$798 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$358 | Average$801 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$481 | Average$787 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$527 | Average$615 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$569 | Average$645 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$832 | Average$903 | FlexibilityNo cancel fee | On-time74% |