How popular is this Panama to San Francisco flight route?

The Panama to San Francisco flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

What are the cheapest airlines to fly from Panama to San Francisco one-way?

One-way options have recently been found by users for as low as $274 on Avianca. Other airlines that offer cheap prices include United Airlines from $517 and Copa Airlines from $852 one-way.

What is the cheapest day to fly from Panama to San Francisco?

Travelers seeking maximum savings on their Panama to San Francisco flight should consider departing on Friday mornings when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

What are the cheapest flights from Panama to San Francisco?

The cheapest flight price from Panama to San Francisco is $372. On average you can expect to pay $973. The most popular route, (Panama City Tocumen Intl - San Francisco), can usually be booked for $486.

What are the most popular airlines that fly from Panama to San Francisco?

When booking a flight from Panama to San Francisco, you may want to consider flying on Avianca, Copa Airlines or United Airlines as they are the most popular for this route.

What is the cheapest day to fly round-trip from Panama to San Francisco?

Flying to your destination on a Monday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to San Francisco. Check prices with Cheapflights to find a great deal for your trip.

How far in advance should I book a flight from Panama to San Francisco?

Find a great deal and save up to 35% by booking at least 36 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Panama to San Francisco within the next two weeks, with the cheapest ticket starting at $642.

What is the cheapest month to fly from Panama to San Francisco?

The best pricing can be found in the month of August. Prices to San Francisco from Panama average $632. You can even find prices in August for less than $632, as users have found deals to San Francisco from as low as $217. The month of March appears to be one of the more expensive times to travel to San Francisco from Panama. Flying in the targeted month can save you up to 8%.

What airport do you fly into for flights to San Francisco from Panama?

If you book a flight to San Francisco from Panama, you will be flying to San Francisco, which is the city’s only airport. San Francisco (SFO) is located 11.8 mi from the center of San Francisco.

Can I find deals for flights from Panama to San Francisco that include hotel bookings?

Yes. In addition to deals on Panama to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to San Francisco.

Can I find deals for business class flights from Panama to San Francisco?

Yes. Cheapflights offers flight deals from Panama to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$565+ Flights from Panama to San Francisco

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Cheap flight deals from Panama to San Francisco

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$479 (Trip.com)
One-way from	$274 (Cheapflightsfares)
Popular in	March
Cheapest in	August
Average price	$598
Good round-trip deal	$574 or less
Good one-way deal	$390 or less

Provider with most accurate pricing for Panama City Tocumen Intl-San Francisco flight deals.

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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-San Francisco flights.

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From Panama to San Francisco

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One-way flight from Panama to San Francisco

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Highest demand for flights based on searches. 4% potential increase in price ($28 potential increase over avg. RT price).

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Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).

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Average for round-trip flights in May 2025

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Price to beat on a round-trip flight from Panama to San Francisco.

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Price to beat on a one-way flight from Panama to San Francisco.

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Find flight deals from Panama to San Francisco

Cheapest flights from Panama to San Francisco
Explore the most affordable flight options available from Panama to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Tue 6/33:40 pmPTY - SFO

1 stop10h 15mAvianca

Tue 7/292:30 amSFO - PTY

1 stop11h 45mAvianca

Deal found 4/29

$479

Fri 9/122:14 pmPTY - SFO

1 stop12h 32mDelta

Thu 9/253:15 pmSFO - PTY

1 stop19h 34mDelta

Deal found 4/30

$512

Wed 8/133:40 pmPTY - SFO

2 stops23h 20mAmerican Airlines

Sun 8/3112:45 amSFO - PTY

2 stops11h 35mAmerican Airlines

Deal found 4/30

$526

Sun 6/83:15 pmPTY - SFO

Nonstop7h 43mUnited Airlines

Thu 6/2611:59 pmSFO - PTY

1 stop16h 38mUnited Airlines

Deal found 4/30

$534

Sun 6/85:50 pmPTY - SFO

Nonstop7h 50mCopa Airlines

Wed 6/251:37 amSFO - PTY

Nonstop7h 04mCopa Airlines

Deal found 4/30

$562

Fri 5/210:28 pmPTY - SFO

1 stop26h 17mMultiple Airlines

Sun 5/412:05 amSFO - PTY

1 stop8h 20mMultiple Airlines

Deal found 4/30

$619

Best flights from Panama to San Francisco
Discover carefully curated flight deals from Panama to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2025.

Tue 6/33:40 pmPTY - SFO

1 stop10h 15mAvianca

Tue 7/292:30 amSFO - PTY

1 stop11h 45mAvianca

Deal found 4/29

$479

Fri 9/122:14 pmPTY - SFO

1 stop12h 32mDelta

Thu 9/253:15 pmSFO - PTY

1 stop19h 34mDelta

Deal found 4/30

$512

Wed 8/133:40 pmPTY - SFO

1 stop21h 33mAmerican Airlines

Mon 9/112:13 pmSFO - PTY

1 stop24h 07mAmerican Airlines

Deal found 4/30

$521

Sun 6/83:15 pmPTY - SFO

Nonstop7h 43mUnited Airlines

Thu 6/2611:59 pmSFO - PTY

1 stop16h 38mUnited Airlines

Deal found 4/30

$534

Sun 6/85:50 pmPTY - SFO

Nonstop7h 50mCopa Airlines

Wed 6/251:37 amSFO - PTY

Nonstop7h 04mCopa Airlines

Deal found 4/30

$562

Tue 6/33:20 amPTY - SFO

2 stops20h 20mMultiple Airlines

Wed 6/1110:55 amSFO - PTY

Nonstop7h 15mMultiple Airlines

Deal found 4/29

$730

Last-minute flights from Panama to San Francisco
Discover last-minute flight deals from Panama to San Francisco. Data last updated May 1, 2025 and is based on user searches.

Fri 5/210:28 pmPTY - SFO

1 stop26h 17mMultiple Airlines

Sun 5/412:05 amSFO - PTY

1 stop8h 20mMultiple Airlines

Deal found 4/30

$619

Tue 5/65:50 pmPTY - SFO

Nonstop7h 50mCopa Airlines

Wed 5/141:37 amSFO - PTY

Nonstop7h 04mCopa Airlines

Deal found 4/29

$795

Tue 5/67:40 amPTY - SFO

1 stop11h 02mMultiple Airlines

Thu 5/157:52 pmSFO - PTY

Nonstop7h 21mMultiple Airlines

Deal found 4/29

$1,126

Thu 5/83:40 pmPTY - SFO

1 stop9h 05mAvianca

Thu 5/152:20 pmSFO - PTY

3 stops17h 50mAvianca

Deal found 4/30

$487

Thu 5/223:15 pmPTY - SFO

Nonstop7h 43mUnited Airlines

Tue 5/2710:55 amSFO - PTY

Nonstop7h 15mUnited Airlines

Deal found 4/30

$603

Fri 5/235:50 pmPTY - SFO

Nonstop7h 50mCopa Airlines

Sun 5/251:37 amSFO - PTY

Nonstop7h 04mCopa Airlines

Deal found 4/30

$717

One-way flights from Panama to San Francisco
Search for one-way flight options from Panama to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 1, 2025.

Sat 5/173:40 pmPTY - SFO

1 stop9h 05mAvianca

Deal found 4/30

$274

Sat 5/1710:05 pmPTY - SFO

3 stops43h 12mMultiple Airlines

Deal found 4/30

$309

Mon 6/23:15 pmPTY - SFO

Nonstop7h 43mUnited Airlines

Deal found 4/30

$517

Sat 5/175:50 pmPTY - SFO

Nonstop7h 50mCopa Airlines

Deal found 4/30

$852

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Tue 6/3

3:40 pm-11:55 pm

1 stop10h 15m

San Francisco

Tue 7/29

2:30 am-4:15 pm

1 stop11h 45m

$479

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Fri 9/12

2:14 pm-12:46 am

1 stop12h 32m

San Francisco

Thu 9/25

3:15 pm-12:49 pm

1 stop19h 34m

$512

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Wed 8/13

3:40 pm-11:13 am

1 stop21h 33m

San Francisco

Mon 9/1

12:13 pm-2:20 pm

1 stop24h 07m

$521

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Sun 6/8

3:15 pm-8:58 pm

Nonstop7h 43m

San Francisco

Thu 6/26

11:59 pm-6:37 pm

1 stop16h 38m

$534

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Sun 6/8

5:50 pm-11:40 pm

Nonstop7h 50m

San Francisco

Wed 6/25

1:37 am-10:41 am

Nonstop7h 04m

$562

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Tue 6/3

3:20 am-9:40 pm

2 stops20h 20m

San Francisco

Wed 6/11

10:55 am-8:10 pm

Nonstop7h 15m

$730

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Sat 5/17

3:40 pm-10:45 pm

1 stop9h 05m

$274

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Sat 5/17

10:05 pm-3:17 pm

3 stops43h 12m

$309

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Mon 6/2

3:15 pm-8:58 pm

Nonstop7h 43m

$517

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Sat 5/17

5:50 pm-11:40 pm

Nonstop7h 50m

$852

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Best time to book a flight from Panama to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Panama with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to San Francisco

What is the cheapest month to book a flight from Panama to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Panama to San Francisco (average of $276). Flying from Panama to San Francisco in June is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to SFO?

A simple way to save on the total cost of your ticket is to fly from Panama to San Francisco in the morning. If you’re flexible enough to do this you can expect to save up to 6% on your trip compared to booking a flight at noon.

Weekly flight availability from Panama to San Francisco

The most flights from PA0 to SFO are scheduled on a Tuesday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

Rainfall in San Francisco by month

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Read reviews from past customers who have flown Delta, Copa Airlines and United Airlines from Panama to San Francisco. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

7,934 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Copa Airlines

7.5

Good

1,415 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines

7.4

Good

8,696 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Avianca

6.7

Okay

2,317 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What airport do you fly into for flights to San Francisco from Panama?
If you book a flight to San Francisco from Panama, you will be flying to San Francisco, which is the city’s only airport. San Francisco (SFO) is located 11.8 mi from the center of San Francisco.
How popular is this Panama to San Francisco flight route?
The Panama to San Francisco flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
What are the cheapest airlines to fly from Panama to San Francisco one-way?
One-way options have recently been found by users for as low as $274 on Avianca. Other airlines that offer cheap prices include United Airlines from $517 and Copa Airlines from $852 one-way.
What are the cheapest flights from Panama to San Francisco?
The cheapest flight price from Panama to San Francisco is $372. On average you can expect to pay $973. The most popular route, (Panama City Tocumen Intl - San Francisco), can usually be booked for $486.
Can I find deals for flights from Panama to San Francisco that include hotel bookings?
Yes. In addition to deals on Panama to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to San Francisco.
Can I find deals for business class flights from Panama to San Francisco?
Yes. Cheapflights offers flight deals from Panama to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Panama to San Francisco (average of $276). Flying from Panama to San Francisco in June is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Roseville

Mountain View

Santa Cruz

Livermore

South San Francisco

Turlock

Manteca

Fairfield

Richmond

Watsonville

Hollister

Newark

Milpitas

Antioch

Sausalito

Hayward

Alameda

Sunnyvale

Campbell

Daly City

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Panama to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
Avianca	Cheapest$341	Average$615	FlexibilityNo cancel fee	On-time71%
Copa Airlines	Cheapest$514	Average$630	FlexibilityNo cancel fee	On-time70%
United Airlines	Cheapest$610	Average$842	FlexibilityNo cancel fee	On-time69%

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$274+ Cheap flights from Panama to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama to San Francisco with Cheapflights

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Cheap flight deals from Panama to San Francisco

Keep the following information in mind while searching for Panama to San Francisco flight deals. Data was last updated May 1, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Panama to San Francisco

Cheapest flights from Panama to San FranciscoExplore the most affordable flight options available from Panama to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Explore the most affordable flight options available from Panama to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama to San Francisco that are best for you.

Best time to book a flight from Panama to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Panama with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Panama to San Francisco

What is the cheapest month to book a flight from Panama to San Francisco?

What is the cheapest time of day to fly from PA to SFO?

Find hourly flight availability from Panama to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Weekly flight availability from Panama to San Francisco

Explore weekly flight availability from Panama to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 1, 2025.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

Reviews of airlines servicing San Francisco

Read reviews from past customers who have flown Delta, Copa Airlines and United Airlines from Panama to San Francisco. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Panama to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to San Francisco from Panama?

How popular is this Panama to San Francisco flight route?

What are the cheapest airlines to fly from Panama to San Francisco one-way?

What are the cheapest flights from Panama to San Francisco?

Can I find deals for flights from Panama to San Francisco that include hotel bookings?

How can I find direct flights from Panama to San Francisco?

Can I find deals for business class flights from Panama to San Francisco?

What is the cheapest month to book a flight from Panama to San Francisco?

Traveling to a place near Panama?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Panama to San Francisco

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Cheapest flights from Panama to San Francisco
Explore the most affordable flight options available from Panama to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.