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$287+ Cheap flights from Panama to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/2. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SFO
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Panama to San Francisco

Keep the following information in mind while searching for Panama to San Francisco flight deals. Data was last updated July 31, 2025.

Round-trip from

$497
(Avianca)

One-way from

$287
(Cheapflightsfares)

Popular in

October

Cheapest in

August

Average price

$602

Good round-trip deal

$642 or less

Good one-way deal

$319 or less
From Panama to San Francisco
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One-way flight from Panama to San Francisco
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Highest demand for flights based on searches. 3% potential increase in price ($20 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from Panama to San Francisco.
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Price to beat on a one-way flight from Panama to San Francisco.
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Find flight deals from Panama to San Francisco

Cheapest flights from Panama to San Francisco
Explore the most affordable flight options available from Panama to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Avianca deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/183:40 pmPTY - SFO
1 stop9h 05mAvianca
Thu 9/252:20 pmSFO - PTY
2 stops17h 50mAvianca
Deal found 7/29$497
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/113:35 pmPTY - SFO
Nonstop7h 35mUnited Airlines
Sat 10/1811:59 pmSFO - PTY
1 stop16h 38mUnited Airlines
Deal found 7/29$507
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/113:15 pmPTY - SFO
2 stops21h 18mAmerican Airlines
Sat 10/1811:59 pmSFO - PTY
1 stop12h 01mAmerican Airlines
Deal found 7/31$536
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/175:50 pmPTY - SFO
Nonstop7h 35mCopa Airlines
Tue 9/231:30 amSFO - PTY
Nonstop7h 11mCopa Airlines
Deal found 7/29$558

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Panama to San Francisco that are best for you.

Fly from

Panama

Fly to

San Francisco

Route

Depart

Return

Price

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Thu 9/18

3:40 pm-10:45 pm

1 stop9h 05m

San Francisco

Thu 9/25

2:20 pm-10:10 am

2 stops17h 50m

$497

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Sat 10/11

3:35 pm-9:10 pm

Nonstop7h 35m

San Francisco

Fri 10/17

12:43 am-2:14 pm

1 stop11h 31m

$507

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Sat 10/11

3:15 pm-10:33 am

2 stops21h 18m

San Francisco

Sat 10/18

11:59 pm-2:00 pm

1 stop12h 01m

$536

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Wed 9/17

5:50 pm-11:25 pm

Nonstop7h 35m

San Francisco

Tue 9/23

1:30 am-10:41 am

Nonstop7h 11m

$558

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Tue 9/2

5:25 pm-12:35 pm

2 stops21h 10m

$287

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Mon 8/11

10:05 pm-8:47 pm

3 stops24h 42m

$375

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Sat 9/20

3:35 pm-9:10 pm

Nonstop7h 35m

$462

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Best time to book a flight from Panama to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to San Francisco

What is the cheapest month to book a flight from Panama to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Panama to San Francisco (average of $276). Flying from Panama to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to SFO?

Find hourly flight availability from Panama to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama to San Francisco in the morning. If you’re flexible enough to do this you can expect to save up to 18% on your trip compared to booking a flight at noon.

Weekly flight availability from Panama to San Francisco

Explore weekly flight availability from Panama to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 31, 2025.

The most flights from PA0 to SFO are scheduled on a Wednesday (4 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated July 31, 2025.
Read through reviews of airlines operating flights from Panama to San Francisco, such as Copa Airlines, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,493 reviews

Crew

8.1

Food

6.8

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Copa Airlines
7.5
Good
1,493 reviews
Copa Airlines
7.5
Good
1,493 reviews

Crew

8.1

Food

6.8

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
United Airlines
7.4
Good
8,900 reviews
Copa Airlines
7.5
Good
1,493 reviews

Crew

8.1

Food

6.8

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
American Airlines
7.2
Good
10,000 reviews
Copa Airlines
7.5
Good
1,493 reviews

Crew

8.1

Food

6.8

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Avianca
6.7
Okay
2,388 reviews
Copa Airlines
7.5
Good
1,493 reviews

Crew

8.1

Food

6.8

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Related info for your journey

Find useful and relevant information for your journey from Panama to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Panama?

    If you book a flight to San Francisco from Panama, you will be flying to San Francisco, which is the city’s only airport. San Francisco (SFO) is located 11.8 mi from the center of San Francisco.

  • How popular is this Panama to San Francisco flight route?

    The Panama to San Francisco flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest flights from Panama to San Francisco?

    The cheapest flight price from Panama to San Francisco is $306. On average you can expect to pay $1,158. The most popular route, (Panama City Tocumen Intl - San Francisco), can usually be booked for $505.

  • Can I find deals for flights from Panama to San Francisco that include hotel bookings?

    Yes. In addition to deals on Panama to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to San Francisco.

  • Can I find deals for business class flights from Panama to San Francisco?

    Yes. Cheapflights offers flight deals from Panama to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Panama to San Francisco (average of $276). Flying from Panama to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Mountain View
Santa Cruz
South San Francisco
Livermore
Turlock
Manteca
Antioch
Hollister
Watsonville
Sunnyvale
Newark
Milpitas
Campbell
Foster City
Capitola
Santa Clara
San Leandro
Burlingame
Redwood City

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Panama to San Francisco

Discover the top 3 airlines that operate flights from Panama to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$474Average$615FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$506Average$642FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$506Average$633FlexibilityNo cancel feeOn-time70%

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