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$298+ Cheap flights from Columbia, MO to San Francisco (COU - SFO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
COU — SFO
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Columbia to San Francisco

Cheapest flights from Columbia to San Francisco
Explore the most affordable flight options available from Columbia to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This United Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/159:00 amCOU - SFO
1 stop6h 38mUnited Airlines
Tue 12/307:00 amSFO - COU
1 stop8h 25mUnited Airlines
Deal found 12/8$473
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:45 amCOU - SFO
1 stop9h 12mUnited Airlines
Mon 12/295:00 amSFO - COU
1 stop7h 35mUnited Airlines
Deal found 12/9$510
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:35 amCOU - SFO
1 stop9h 26mAmerican Airlines
Tue 12/3010:49 pmSFO - COU
1 stop8h 50mAmerican Airlines
Deal found 12/10$531
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1512:06 pmCOU - SFO
2 stops11h 24mAmerican Airlines
Tue 12/3010:49 pmSFO - COU
1 stop8h 50mAmerican Airlines
Deal found 12/8$537
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:34 pmCOU - SFO
2 stops15h 05mUnited Airlines
Tue 12/305:00 amSFO - COU
1 stop7h 35mUnited Airlines
Deal found 12/10$793
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:50 amCOU - SFO
2 stops11h 08mAmerican Airlines
Mon 12/299:15 amSFO - COU
2 stops10h 44mAmerican Airlines
Deal found 12/9$909
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2610:09 amCOU - SFO
2 stops10h 28mAmerican Airlines
Tue 12/3010:23 amSFO - COU
2 stops10h 09mAmerican Airlines
Deal found 12/10$1,109

Find flight deals from Columbia to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Columbia (COU) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$298
(United Airlines)

Popular in

September

Cheapest in

November

Average price

$575
Provider with most accurate pricing for Columbia Regional-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbia Regional-San Francisco flights.
Search Deals
From Columbia Regional to San Francisco
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($22 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Columbia to San Francisco that are best for you.

Fly from

Columbia

Fly to

San Francisco

Route

Depart

Return

Price

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Mon 3/2

3:10 pm-9:20 pm

1 stop8h 10m

San Francisco

Mon 4/27

12:45 am-10:29 am

1 stop7h 44m

$298

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Tue 2/24

12:27 pm-5:05 pm

1 stop6h 38m

San Francisco

Tue 3/3

8:00 am-5:31 pm

1 stop7h 31m

$342

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Wed 2/18

12:27 pm-5:15 pm

1 stop6h 48m

San Francisco

Sat 2/28

8:00 am-5:37 pm

1 stop7h 37m

$342

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Sat 1/10

8:09 am-2:07 pm

1 stop7h 58m

San Francisco

Tue 1/13

11:56 pm-10:42 am

1 stop8h 46m

$368

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Fri 1/16

3:10 pm-9:30 pm

1 stop8h 20m

San Francisco

Tue 1/20

11:56 pm-10:42 am

1 stop8h 46m

$388

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Thu 2/12

8:00 am-2:07 pm

1 stop8h 07m

San Francisco

Thu 2/19

11:59 pm-10:33 am

1 stop8h 34m

$393

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Compare providers for flights from Columbia to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbia to San Francisco in December.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Columbia, Missouri-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Columbia, Missouri-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Columbia, Missouri-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Columbia, Missouri-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbia, Missouri-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Columbia to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to San Francisco

What is the cheapest month to book a flight from Columbia, Missouri to San Francisco?

Currently, November is the cheapest month in which you can book a flight from Columbia, Missouri to San Francisco (average of $284). Flying from Columbia, Missouri to San Francisco in March is currently the most expensive (average of $654). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from COU to SFO?

Find hourly flight availability from Columbia to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 30% on flights from Columbia, Missouri to San Francisco by exploring options for tickets in the morning.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated December 12, 2025.
Get a feel of what it's like to fly with American Airlines from Columbia to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,050 reviews

Boarding

7.5

Overall

7.2

Comfort

7.2

Crew

8.0

Food

6.5

Entertainment

6.9

Reviews

1 / 20
8.0
Excellent

Douglas,Sep 2023

RNO - LAX

There was a maintenance issue that caused us to depart over 1 hour late.
American Airlines
7.2
Good
11,050 reviews
American Airlines
7.2
Good
11,050 reviews

Boarding

7.5

Overall

7.2

Comfort

7.2

Crew

8.0

Food

6.5

Entertainment

6.9

Reviews

1 / 20
8.0
Excellent

Douglas,Sep 2023

RNO - LAX

There was a maintenance issue that caused us to depart over 1 hour late.

Related info for your journey

Find useful and relevant information for your journey from Columbia to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbia, Missouri to San Francisco?

    United Airlines and American Airlines can get you from Columbia, Missouri to San Francisco in just under 6h 38m. Your travel time can differ by up to 1h 32m. Columbia, Missouri and San Francisco are separated by a distance of 1631 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Columbia, Missouri to San Francisco round-trip?

    Currently priced at $377, American Airlines will fly you from Columbia, Missouri to San Francisco and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. American Airlines is 28% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Columbia to San Francisco that include hotel bookings?

    Yes. In addition to deals on Columbia to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to San Francisco.

  • Can I find deals for business class flights from Columbia to San Francisco?

    Yes. Cheapflights offers flight deals from Columbia to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia, Missouri to San Francisco?

    Currently, November is the cheapest month in which you can book a flight from Columbia, Missouri to San Francisco (average of $284). Flying from Columbia, Missouri to San Francisco in March is currently the most expensive (average of $654). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
South San Francisco
Santa Cruz
Livermore
Turlock
Manteca
Watsonville
Sunnyvale
Santa Clara
San Bruno
Redwood City
Daly City
Vallejo
Hollister
Foster City
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Davis
San Ramon
Burlingame
Milpitas

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Top airline flying from Columbia to San Francisco

Discover the top airline that operate flights from Columbia to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$377Average$526FlexibilityNo cancel feeOn-time71%

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