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$278+ Cheap flights from Columbia, MO to San Francisco (COU - SFO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
COU — SFO
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Columbia to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Columbia (COU) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$278
(United Airlines)

Popular in

September

Cheapest in

August

Average price

$791
From Columbia Regional to San Francisco
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($30 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Columbia to San Francisco

Cheapest flights from Columbia to San Francisco
Explore the most affordable flight options available from Columbia to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/89:00 amCOU - SFO
1 stop8h 16mUnited Airlines
Sat 11/155:10 amSFO - COU
1 stop7h 16mUnited Airlines
Deal found 9/16$278
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/29:01 amCOU - SFO
1 stop8h 11mUnited Airlines
Mon 10/65:15 amSFO - COU
1 stop7h 02mUnited Airlines
Deal found 9/17$328
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/82:05 pmCOU - SFO
1 stop8h 54mAmerican Airlines
Sat 11/151:10 pmSFO - COU
2 stops7h 29mAmerican Airlines
Deal found 9/16$348
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/159:01 amCOU - SFO
1 stop8h 11mUnited Airlines
Wed 10/225:15 amSFO - COU
1 stop7h 02mUnited Airlines
Deal found 9/16$378
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/151:49 pmCOU - SFO
1 stop8h 38mAmerican Airlines
Wed 10/226:00 amSFO - COU
1 stop8h 42mAmerican Airlines
Deal found 9/16$387
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:00 amCOU - SFO
2 stops16h 05mUnited Airlines
Sun 12/710:40 amSFO - COU
1 stop8h 42mUnited Airlines
Deal found 9/16$432
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/221:49 pmCOU - SFO
1 stop8h 38mAmerican Airlines
Sun 10/266:00 amSFO - COU
1 stop8h 58mAmerican Airlines
Deal found 9/16$446
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/229:01 amCOU - SFO
2 stops14h 46mUnited Airlines
Sun 10/268:55 pmSFO - COU
1 stop21h 56mUnited Airlines
Deal found 9/16$500

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Columbia to San Francisco that are best for you.

Fly from

Columbia

Fly to

San Francisco

Route

Depart

Return

Price

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Sat 11/8

9:00 am-3:16 pm

1 stop8h 16m

San Francisco

Sat 11/15

5:10 am-2:26 pm

1 stop7h 16m

$278

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Thu 12/4

9:00 am-1:38 pm

1 stop6h 38m

San Francisco

Sun 12/7

7:00 am-5:40 pm

1 stop8h 40m

$278

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Tue 2/24

7:21 am-2:16 pm

1 stop8h 55m

San Francisco

Tue 3/3

5:00 am-2:38 pm

1 stop7h 38m

$342

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Sat 11/8

2:05 pm-8:59 pm

1 stop8h 54m

San Francisco

Sat 11/15

1:10 pm-10:39 pm

2 stops7h 29m

$348

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Wed 3/4

9:00 am-1:33 pm

1 stop6h 33m

San Francisco

Sat 3/7

5:30 am-2:29 pm

1 stop6h 59m

$368

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Wed 10/15

9:01 am-3:12 pm

1 stop8h 11m

San Francisco

Wed 10/22

5:15 am-2:17 pm

1 stop7h 02m

$378

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Wed 10/15

1:49 pm-8:27 pm

1 stop8h 38m

San Francisco

Wed 10/22

6:00 am-4:42 pm

1 stop8h 42m

$387

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Best time to book a flight from Columbia to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to San Francisco

What is the cheapest month to book a flight from Columbia, Missouri to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Columbia, Missouri to San Francisco (average of $276). Flying from Columbia, Missouri to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from COU to SFO?

Find hourly flight availability from Columbia to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 13% on flights from Columbia, Missouri to San Francisco by exploring options for tickets in the morning.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated September 17, 2025.
Get a feel of what it's like to fly with American Airlines from Columbia to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Comfort

7.2

Crew

8.0

Entertainment

6.9

Food

6.4

Overall

7.2

Reviews

1 / 20
8.0
Excellent

Douglas,Sep 2023

RNO - LAX

There was a maintenance issue that caused us to depart over 1 hour late.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Comfort

7.2

Crew

8.0

Entertainment

6.9

Food

6.4

Overall

7.2

Reviews

1 / 20
8.0
Excellent

Douglas,Sep 2023

RNO - LAX

There was a maintenance issue that caused us to depart over 1 hour late.

Related info for your journey

Find useful and relevant information for your journey from Columbia to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbia, Missouri to San Francisco?

    United Airlines and American Airlines can get you from Columbia, Missouri to San Francisco in just under 8h 16m. Your travel time can differ by up to 39m. Columbia, Missouri and San Francisco are separated by a distance of 1631 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Columbia, Missouri to San Francisco round-trip?

    Currently priced at $377, American Airlines will fly you from Columbia, Missouri to San Francisco and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. American Airlines is 27% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Columbia to San Francisco that include hotel bookings?

    Yes. In addition to deals on Columbia to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to San Francisco.

  • Can I find deals for business class flights from Columbia to San Francisco?

    Yes. Cheapflights offers flight deals from Columbia to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia, Missouri to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Columbia, Missouri to San Francisco (average of $276). Flying from Columbia, Missouri to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
South San Francisco
Turlock
Antioch
Watsonville
Santa Clara
Manteca
Sunnyvale
Hollister
Vacaville
Foster City
Union City
Vallejo
Burlingame
Redwood City
San Mateo
San Leandro
Lathrop

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Columbia to San Francisco

Discover the top airline that operate flights from Columbia to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$377Average$511FlexibilityNo cancel feeOn-time71%

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