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$73+ Cheap flights from Mississippi to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SAN
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
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Cheap flight deals from Mississippi to San Diego

Cheapest flights from Mississippi to San Diego
Explore the most affordable flight options available from Mississippi to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:11 pmBTR - SAN
1 stop8h 35mUnited Airlines
Thu 1/18:00 amSAN - BTR
1 stop7h 32mUnited Airlines
Deal found 12/13$237
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/243:46 pmBTR - SAN
1 stop7h 10mDelta
Thu 12/258:00 amSAN - BTR
1 stop9h 48mDelta
Deal found 12/14$277
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:07 amBTR - SAN
1 stop7h 56mDelta
Wed 12/2410:30 pmSAN - BTR
1 stop9h 19mDelta
Deal found 12/14$278
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:34 amBTR - SAN
1 stop6h 52mDelta
Thu 12/2510:30 pmSAN - BTR
1 stop9h 19mDelta
Deal found 12/14$329
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:48 pmBTR - SAN
1 stop6h 58mUnited Airlines
Thu 12/256:30 amSAN - BTR
2 stops10h 53mUnited Airlines
Deal found 12/14$332
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/191:48 pmBTR - SAN
1 stop8h 28mUnited Airlines
Thu 12/258:00 amSAN - BTR
1 stop7h 32mUnited Airlines
Deal found 12/14$348
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2112:11 pmBTR - SAN
2 stops12h 21mUnited Airlines
Thu 12/256:30 amSAN - BTR
2 stops10h 53mUnited Airlines
Deal found 12/14$358
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/224:28 pmBTR - SAN
1 stop7h 28mAmerican Airlines
Tue 12/307:14 amSAN - BTR
1 stop6h 36mAmerican Airlines
Deal found 12/15$359
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/142:00 pmBTR - SAN
1 stop7h 56mUnited Airlines
Thu 12/1810:25 amSAN - BTR
1 stop6h 58mUnited Airlines
Deal found 12/14$369
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/153:57 pmBTR - SAN
1 stop5h 59mUnited Airlines
Thu 12/1811:12 amSAN - BTR
2 stops8h 06mUnited Airlines
Deal found 12/14$374
This Booking.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:07 pmMEM - SAN
1 stop25h 08mFrontier
Sat 1/34:47 pmSAN - MEM
1 stop24h 25mFrontier
Deal found 12/14$408
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:54 pmMEM - SAN
1 stop20h 17mMultiple Airlines
Sat 1/37:21 pmSAN - MEM
2 stops21h 51mMultiple Airlines
Deal found 12/14$455

Find flight deals from Mississippi to San Diego

Keep the following information in mind while searching for Mississippi to San Diego flight deals. Data was last updated December 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$158
(Kiwi.com)

One-way from

$73
(Trip.com)

Popular in

March

Cheapest in

August

Average price

$384
Provider with most accurate pricing for Jackson-Evers Intl-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-San Diego flights.
Search Deals
From Mississippi to San Diego
Search Deals
One-way flight from Mississippi to San Diego
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Mississippi to San Diego that are best for you.

Fly from

Mississippi

Fly to

San Diego

Route

Depart

Return

Price

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Fri 1/23

3:12 pm-12:08 am

1 stop10h 56m

San Diego

Mon 1/26

11:49 am-10:49 am

2 stops45h 00m

$219

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Wed 12/24

12:11 pm-6:46 pm

1 stop8h 35m

San Diego

Thu 1/1

8:00 am-5:32 pm

1 stop7h 32m

$237

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Tue 3/10

12:07 pm-7:48 pm

2 stops9h 41m

San Diego

Tue 3/17

12:16 pm-7:33 pm

1 stop5h 17m

$242

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Thu 1/15

1:57 pm-6:36 pm

1 stop6h 39m

San Diego

Mon 1/19

12:11 pm-7:48 pm

1 stop5h 37m

$267

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Fri 2/6

1:03 pm-7:12 pm

1 stop8h 09m

San Diego

Sun 2/8

9:21 am-6:03 pm

1 stop6h 42m

$273

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Fri 1/9

2:19 pm-7:39 pm

1 stop7h 20m

San Diego

Mon 1/12

10:30 pm-9:52 am

1 stop9h 22m

$277

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Mon 1/5

2:19 pm-7:39 pm

1 stop7h 20m

San Diego

Mon 1/12

10:30 pm-9:52 am

1 stop9h 22m

$277

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Mon 12/22

6:07 am-12:03 pm

1 stop7h 56m

San Diego

Thu 12/25

6:15 am-3:01 pm

1 stop6h 46m

$278

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Fri 2/27

4:55 pm-10:00 pm

1 stop7h 05m

San Diego

Tue 3/3

12:16 pm-7:34 pm

1 stop5h 18m

$278

MobileSan Diego

MOB - SAN

MOBSAN

Mobile

Thu 1/15

10:44 am-7:54 pm

2 stops11h 10m

San Diego

Mon 1/19

12:11 pm-9:59 pm

1 stop7h 48m

$282

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 54 results
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Best time to book a flight from Mississippi to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to San Diego

What is the cheapest month to book a flight from Mississippi to San Diego?

Currently, January is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $196). Flying from Mississippi to San Diego in April is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to SAN?

Find hourly flight availability from Mississippi to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 16, 2025.

It’s typically best to fly out from Mississippi to San Diego in the afternoon. Doing so could potentially save you 45% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Mississippi to San Diego?

Use this chart to determine the cheapest time to fly round-trip from Mississippi to San Diego. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mississippi to San Diego flight should consider departing on Saturday mornings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Mississippi to San Diego?

Related info for your journey

Find useful and relevant information for your journey from Mississippi to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Mississippi?

    For a flight from Mississippi to San Diego, you will be flying into San Diego. San Diego (SAN) is just 2.6 mi from the center of the city.

  • How long is the flight from Mississippi to San Diego?

    United Airlines, American Airlines, and Delta can get you from Mississippi to San Diego in just under 7h 20m. Your travel time can differ by up to 1h 15m. Mississippi and San Diego are separated by a distance of 1535 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mississippi to San Diego one-way?

    One-way options have recently been found by users for as low as $138 on Delta. Other airlines that offer cheap prices include American Airlines from $138 and United Airlines from $148 one-way.

  • What are the most popular routes from Mississippi to San Diego?

    The most popular flight routes from Mississippi to San Diego are Memphis - San Diego, Baton Rouge Ryan - San Diego and Jackson-Evers Intl - San Diego.

  • Can I find deals for flights from Mississippi to San Diego that include hotel bookings?

    Yes. In addition to deals on Mississippi to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to San Diego.

  • Can I find deals for business class flights from Mississippi to San Diego?

    Yes. Cheapflights offers flight deals from Mississippi to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to San Diego?

    Currently, January is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $196). Flying from Mississippi to San Diego in April is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
National City
La Mesa
Poway
Julian
Lemon Grove

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Alternative routes for Mississippi to San Diego

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Top 4 airlines flying from Mississippi to San Diego

Discover the top 4 airlines that operate flights from Mississippi to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$196Average$427FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$273Average$474FlexibilityNo cancel feeOn-time69%
DeltaCheapest$276Average$355FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$367Average$532FlexibilityNo cancel feeOn-time63%

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