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$65+ Cheap flights from Mississippi to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SAN
nov. 28 — dic. 51
vie. 11/28
vie. 12/5
1 adult, Economy
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Cheap flight deals from Mississippi to San Diego

Keep the following information in mind while searching for Mississippi to San Diego flight deals. Data was last updated octubre 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$200
(Kiwi.com)

One-way from

$65
(Priceline)

Popular in

October

Cheapest in

August

Average price

$617
Provider with most accurate pricing for Jackson-Evers Intl-San Diego flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-San Diego flights.
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From Mississippi to San Diego
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One-way flight from Mississippi to San Diego
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Highest demand for flights based on searches. 10% potential increase in price ($53 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Mississippi to San Diego

Cheapest flights from Mississippi to San Diego
Explore the most affordable flight options available from Mississippi to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 29, 2025.

This Frontier deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/48:07 pmMEM - SAN
1 stop25h 08mFrontier
jue. 12/116:34 amSAN - MEM
1 stop10h 38mFrontier
Deal found 10/29$131
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/1312:23 pmMEM - SAN
1 stop26h 12mMultiple Airlines
dom. 11/163:59 pmSAN - MEM
1 stop18h 32mMultiple Airlines
Deal found 10/29$200
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/129:33 pmMEM - SAN
1 stop17h 02mMultiple Airlines
mar. 11/186:58 amSAN - MEM
2 stops35h 40mMultiple Airlines
Deal found 10/27$211
This Booking.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/108:10 pmMEM - SAN
1 stop17h 57mFrontier
mié. 11/121:37 pmSAN - MEM
1 stop27h 45mFrontier
Deal found 10/28$224
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/119:33 pmMEM - SAN
2 stops24h 51mMultiple Airlines
dom. 11/163:59 pmSAN - MEM
1 stop18h 32mMultiple Airlines
Deal found 10/28$229
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/267:59 pmMEM - SAN
1 stop30h 00mFrontier
mié. 12/36:25 amSAN - MEM
2 stops27h 41mFrontier
Deal found 10/29$230
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/129:33 pmMEM - SAN
1 stop17h 02mMultiple Airlines
sáb. 11/158:00 amSAN - MEM
2 stops25h 28mMultiple Airlines
Deal found 10/29$231
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/141:21 pmMEM - SAN
1 stop12h 27mMultiple Airlines
dom. 11/163:59 pmSAN - MEM
1 stop18h 32mMultiple Airlines
Deal found 10/29$239
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/57:42 pmMEM - SAN
2 stops22h 10mMultiple Airlines
dom. 12/76:34 amSAN - MEM
1 stop10h 38mMultiple Airlines
Deal found 10/28$241
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/512:10 pmMEM - SAN
2 stops13h 49mMultiple Airlines
sáb. 12/64:47 pmSAN - MEM
1 stop24h 25mMultiple Airlines
Deal found 10/28$247
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/229:17 pmMEM - SAN
1 stop16h 54mMultiple Airlines
lun. 12/297:21 pmSAN - MEM
2 stops21h 51mMultiple Airlines
Deal found 10/29$254
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/1110:32 amBTR - SAN
1 stop9h 46mDelta
mar. 12/1612:24 pmSAN - BTR
1 stop7h 29mDelta
Deal found 10/27$289

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 29, 2025.
Use the filters below to find and compare flights from Mississippi to San Diego that are best for you.

Fly from

Mississippi

Fly to

San Diego

Route

Depart

Return

Price

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

mar. 11/11

9:33 pm-8:24 pm

2 stops24h 51m

San Diego

dom. 11/16

3:59 pm-12:31 pm

1 stop18h 32m

$229

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

mié. 1/7

5:54 pm-12:38 pm

1 stop20h 44m

San Diego

dom. 1/11

2:50 pm-12:31 pm

1 stop19h 41m

$230

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

jue. 1/22

8:08 pm-11:30 am

1 stop17h 22m

San Diego

lun. 1/26

1:33 pm-3:14 pm

2 stops23h 41m

$273

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

vie. 12/26

9:27 pm-12:38 pm

1 stop17h 11m

San Diego

lun. 12/29

4:47 pm-7:12 pm

1 stop24h 25m

$281

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

jue. 11/13

8:10 pm-11:50 pm

1 stop5h 40m

San Diego

dom. 11/16

6:41 am-7:15 pm

1 stop10h 34m

$288

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

jue. 12/11

10:32 am-6:18 pm

1 stop9h 46m

San Diego

lun. 12/15

12:24 pm-9:53 pm

1 stop7h 29m

$289

MobileSan Diego

MOB - SAN

MOBSAN

Mobile

jue. 12/4

7:36 pm-11:53 pm

1 stop6h 17m

San Diego

lun. 12/8

10:23 pm-10:24 am

1 stop10h 01m

$289

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

jue. 12/11

10:32 am-6:18 pm

1 stop9h 46m

San Diego

mar. 12/16

12:24 pm-9:53 pm

1 stop7h 29m

$289

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

vie. 12/12

6:01 pm-11:35 pm

1 stop7h 34m

San Diego

dom. 12/14

6:15 am-5:16 pm

1 stop9h 01m

$289

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

vie. 2/20

6:00 pm-11:11 pm

1 stop7h 11m

San Diego

sáb. 2/28

10:40 pm-9:41 am

1 stop9h 01m

$289

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to San Diego

What is the cheapest month to book a flight from Mississippi to San Diego?

Currently, August is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $218). Flying from Mississippi to San Diego in April is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to SAN?

Find hourly flight availability from Mississippi to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 29, 2025.

It’s typically best to fly out from Mississippi to San Diego in the afternoon. Doing so could potentially save you 45% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Mississippi to San Diego?

Use this chart to determine the cheapest time to fly round-trip from Mississippi to San Diego. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mississippi to San Diego flight should consider departing on Saturday mornings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Mississippi to San Diego?

Related info for your journey

Find useful and relevant information for your journey from Mississippi to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Mississippi?

    For a flight from Mississippi to San Diego, you will be flying into San Diego. San Diego (SAN) is just 2.6 mi from the center of the city.

  • How long is the flight from Mississippi to San Diego?

    Frontier, Delta, and American Airlines can get you from Mississippi to San Diego in just under 5h 40m. Your travel time can differ by up to 4h 06m. Mississippi and San Diego are separated by a distance of 1563 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mississippi to San Diego one-way?

    One-way options have recently been found by users for as low as $150 on United Airlines. Other airlines that offer cheap prices include American Airlines from $195 and Delta from $215 one-way.

  • What are the most popular routes from Mississippi to San Diego?

    The most popular flight routes from Mississippi to San Diego are Memphis - San Diego, Gulfport Biloxi Regional - San Diego and Jackson-Evers Intl - San Diego.

  • Can I find deals for flights from Mississippi to San Diego that include hotel bookings?

    Yes. In addition to deals on Mississippi to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to San Diego.

  • Can I find deals for business class flights from Mississippi to San Diego?

    Yes. Cheapflights offers flight deals from Mississippi to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $218). Flying from Mississippi to San Diego in April is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
National City

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Alternative routes for Mississippi to San Diego

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Top 4 airlines flying from Mississippi to San Diego

Discover the top 4 airlines that operate flights from Mississippi to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$276Average$355FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$288Average$497FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$288Average$455FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$390Average$532FlexibilityNo cancel feeOn-time63%

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