San Diego

$76+ Cheap flights from Mississippi to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/13. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SAN
Mar 14 — Mar 211
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Cheap flight deals from Mississippi to San Diego

Cheapest flights from Mississippi to San Diego
Explore the most affordable flight options available from Mississippi to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/58:09 pm
MEM
-
SAN
1 stop13h 56m
Frontier
Mon 3/96:25 am
SAN
-
MEM
1 stop10h 52m
Frontier
Deal found 2/8$191
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:17 pm
MEM
-
SAN
1 stop18h 35m
Multiple Airlines
Thu 5/79:07 pm
SAN
-
MEM
1 stop21h 20m
Multiple Airlines
Deal found 2/9$199
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/58:09 pm
MEM
-
SAN
1 stop13h 56m
Multiple Airlines
Sun 3/89:07 pm
SAN
-
MEM
1 stop21h 26m
Multiple Airlines
Deal found 2/9$205
This Frontier deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/18:09 pm
MEM
-
SAN
1 stop5h 59m
Frontier
Sat 3/79:18 pm
SAN
-
MEM
1 stop15h 24m
Frontier
Deal found 2/10$206
This Trip.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/22:47 pm
MEM
-
SAN
1 stop11h 18m
Frontier
Sun 4/56:25 am
SAN
-
MEM
1 stop7h 11m
Frontier
Deal found 2/11$210
This Frontier deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/144:26 pm
MEM
-
SAN
1 stop9h 35m
Frontier
Sun 5/176:25 am
SAN
-
MEM
1 stop7h 16m
Frontier
Deal found 2/9$211
This Priceline deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/18:09 pm
MEM
-
SAN
1 stop5h 59m
Frontier
Sun 3/86:25 am
SAN
-
MEM
1 stop7h 17m
Frontier
Deal found 2/9$220
This CheapOair deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:06 pm
MEM
-
SAN
1 stop17h 22m
Frontier
Fri 2/278:35 am
SAN
-
MEM
1 stop8h 36m
Frontier
Deal found 2/10$221
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/119:17 pm
MEM
-
SAN
1 stop18h 35m
Multiple Airlines
Sun 5/176:25 am
SAN
-
MEM
1 stop7h 16m
Multiple Airlines
Deal found 2/9$222
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/58:09 pm
MEM
-
SAN
1 stop13h 56m
Multiple Airlines
Mon 3/99:18 pm
SAN
-
MEM
2 stops35h 02m
Multiple Airlines
Deal found 2/8$225
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/119:17 pm
MEM
-
SAN
1 stop18h 35m
Multiple Airlines
Mon 5/186:25 am
SAN
-
MEM
2 stops25h 54m
Multiple Airlines
Deal found 2/9$229
This CheapOair deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/88:30 pm
MEM
-
SAN
1 stop21h 43m
Frontier
Wed 3/112:08 pm
SAN
-
MEM
1 stop27h 27m
Frontier
Deal found 2/10$231

Find flight deals from Mississippi to San Diego

Keep the following information in mind while searching for Mississippi to San Diego flight deals. Data was last updated February 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$191
(Kiwi.com)

One-way from

$76
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$545
Provider with most accurate pricing for Jackson-Evers Intl-San Diego flight deals.
Provider most trusted by Cheapflights users for Jackson-Evers Intl-San Diego flights.
From Mississippi to San Diego
One-way flight from Mississippi to San Diego
Highest demand for flights based on searches. 15% potential increase in price ($94 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
Average for round-trip flights in February 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Mississippi to San Diego that are best for you.

Fly from

Mississippi

Fly to

San Diego

Route

Depart

Return

Price

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Thu 3/5

8:09 pm-8:05 am

1 stop13h 56m

San Diego

Sun 3/8

9:07 pm-8:33 pm

1 stop21h 26m

$205

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Thu 4/2

2:47 pm-12:05 am

1 stop11h 18m

San Diego

Sun 4/5

6:25 am-3:36 pm

1 stop7h 11m

$210

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Mon 5/11

9:17 pm-1:52 pm

1 stop18h 35m

San Diego

Tue 5/19

7:15 am-10:19 am

2 stops25h 04m

$221

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Tue 2/24

12:14 pm-6:33 pm

1 stop8h 19m

San Diego

Sat 2/28

1:45 pm-9:32 pm

1 stop5h 47m

$237

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Thu 4/30

4:26 pm-8:34 am

1 stop18h 08m

San Diego

Tue 5/5

7:15 am-10:07 am

2 stops24h 52m

$244

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Thu 4/9

2:47 pm-11:08 am

2 stops22h 21m

San Diego

Sun 4/12

9:56 pm-8:27 pm

1 stop20h 31m

$249

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Sun 3/29

4:27 pm-12:08 am

1 stop9h 41m

San Diego

Sun 4/5

6:25 am-3:36 pm

1 stop7h 11m

$251

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Sun 3/8

2:35 pm-12:16 am

2 stops11h 41m

San Diego

Wed 3/11

8:25 am-1:58 pm

1 stop27h 33m

$256

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Fri 3/13

1:36 pm-6:51 pm

1 stop7h 15m

San Diego

Tue 3/17

10:30 pm-9:45 am

1 stop9h 15m

$277

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Sat 5/9

7:15 am-2:56 pm

2 stops9h 41m

San Diego

Wed 5/13

6:15 am-3:31 pm

1 stop7h 16m

$277

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/11

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to San Diego

What is the cheapest month to book a flight from Mississippi to San Diego?

Currently, February is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $167). Flying from Mississippi to San Diego in April is currently the most expensive (average of $379). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to San Diego from Mississippi?

    For a flight from Mississippi to San Diego, you will be flying into San Diego. San Diego (SAN) is just 2.6 mi from the center of the city.

  • How long is the flight from Mississippi to San Diego?

    Frontier, United Airlines, and Delta can get you from Mississippi to San Diego in just under 7h 15m. Your travel time can differ by up to 4h 03m. Mississippi and San Diego are separated by a distance of 1535 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mississippi to San Diego one-way?

    One-way options have recently been found by users for as low as $138 on Delta. Other airlines that offer cheap prices include American Airlines from $138 and United Airlines from $148 one-way.

  • What are the most popular routes from Mississippi to San Diego?

  • Can I find deals for flights from Mississippi to San Diego that include hotel bookings?

    Yes. In addition to deals on Mississippi to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to San Diego.

  • Can I find deals for business class flights from Mississippi to San Diego?

    Yes. Cheapflights offers flight deals from Mississippi to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to San Diego?

    Currently, February is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $167). Flying from Mississippi to San Diego in April is currently the most expensive (average of $379). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to San Diego

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Mississippi to San Diego

Discover the top 4 airlines that operate flights from Mississippi to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$138Average$350FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$447FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$273Average$475FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$367Average$568FlexibilityNo cancel feeOn-time63%

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