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$57+ Cheap flights from Mississippi to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SAN
okt. 11 — okt. 181
za 10/11
za 10/18
1 adult, Economy
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Cheap flight deals from Mississippi to San Diego

Keep the following information in mind while searching for Mississippi to San Diego flight deals. Data was last updated september 11, 2025.

Round-trip from

$179
(Kiwi.com)

One-way from

$57
(Cheapflightsfares)

Popular in

December

Cheapest in

August

Average price

$427
From Mississippi to San Diego
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One-way flight from Mississippi to San Diego
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Highest demand for flights based on searches. 7% potential increase in price ($36 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Mississippi to San Diego

Cheapest flights from Mississippi to San Diego
Explore the most affordable flight options available from Mississippi to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on september 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 10/178:12 pmMEM - SAN
1 stop19h 16mMultiple Airlines
ma 10/206:25 amSAN - MEM
1 stop29h 37mMultiple Airlines
Deal found 9/9$179
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 11/53:30 pmMEM - SAN
1 stop9h 55mSouthwest
di 11/116:20 amSAN - MEM
1 stop7h 45mSouthwest
Deal found 9/9$184
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 10/152:57 pmMEM - SAN
1 stop8h 23mMultiple Airlines
do 11/133:59 pmSAN - MEM
1 stop18h 32mMultiple Airlines
Deal found 9/9$202
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 10/271:45 pmMEM - SAN
1 stop11h 19mMultiple Airlines
vr 10/313:59 pmSAN - MEM
1 stop20h 03mMultiple Airlines
Deal found 9/11$212
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 11/125:15 amMEM - SAN
1 stop6h 41mAmerican Airlines
wo 11/191:25 pmSAN - MEM
1 stop7h 00mAmerican Airlines
Deal found 9/10$213
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 10/294:00 pmJAN - SAN
1 stop9h 10mSouthwest
di 11/46:50 amSAN - JAN
1 stop8h 50mSouthwest
Deal found 9/11$214
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 11/68:10 pmMEM - SAN
1 stop29h 40mFrontier
wo 11/122:24 pmSAN - MEM
1 stop26h 58mFrontier
Deal found 9/10$222
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 10/312:57 pmMEM - SAN
1 stop10h 51mMultiple Airlines
zo 11/28:30 amSAN - MEM
1 stop26h 25mMultiple Airlines
Deal found 9/10$223
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 10/312:57 pmMEM - SAN
1 stop10h 51mMultiple Airlines
ma 11/33:59 pmSAN - MEM
1 stop20h 03mMultiple Airlines
Deal found 9/10$227
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 10/292:57 pmMEM - SAN
1 stop23h 38mMultiple Airlines
zo 11/28:30 amSAN - MEM
1 stop26h 25mMultiple Airlines
Deal found 9/10$230
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 10/92:57 pmMEM - SAN
1 stop10h 07mMultiple Airlines
do 10/166:25 amSAN - MEM
1 stop27h 40mMultiple Airlines
Deal found 9/9$236
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 10/294:00 pmJAN - SAN
1 stop9h 10mSouthwest
ma 11/36:50 amSAN - JAN
1 stop8h 50mSouthwest
Deal found 9/10$271

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated september 11, 2025.
Use the filters below to find and compare flights from Mississippi to San Diego that are best for you.

Fly from

Mississippi

Fly to

San Diego

Route

Depart

Return

Price

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

wo 11/5

6:00 am-2:25 pm

1 stop10h 25m

San Diego

di 11/11

7:10 am-5:15 pm

2 stops8h 05m

$189

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

wo 10/15

2:57 pm-9:20 pm

1 stop8h 23m

San Diego

do 11/13

3:59 pm-12:31 pm

1 stop18h 32m

$202

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

wo 11/12

7:27 am-12:00 pm

1 stop6h 33m

San Diego

wo 11/19

7:21 am-4:06 pm

1 stop6h 45m

$213

JacksonSan Diego

JAN - SAN

JANSAN

Jackson-Evers Intl

wo 10/29

4:00 pm-11:10 pm

1 stop9h 10m

San Diego

di 11/4

10:20 am-7:55 pm

2 stops7h 35m

$219

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

do 11/6

8:10 pm-11:50 pm

1 stop29h 40m

San Diego

wo 11/12

2:24 pm-7:22 pm

1 stop26h 58m

$222

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

vr 10/31

2:57 pm-11:48 pm

1 stop10h 51m

San Diego

ma 11/3

3:59 pm-2:02 pm

1 stop20h 03m

$227

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

wo 11/5

3:52 pm-8:24 am

2 stops18h 32m

San Diego

zo 11/9

6:41 am-7:15 pm

1 stop10h 34m

$237

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

ma 11/3

4:59 pm-10:20 pm

1 stop7h 21m

San Diego

di 11/11

10:23 pm-9:44 am

1 stop9h 21m

$245

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

do 11/6

12:35 pm-10:50 pm

1 stop12h 15m

San Diego

di 11/11

11:45 am-9:15 pm

1 stop7h 30m

$255

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

wo 10/29

2:57 pm-11:17 am

2 stops22h 20m

San Diego

zo 11/2

8:30 am-12:55 pm

1 stop26h 25m

$257

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to San Diego

What is the cheapest month to book a flight from Mississippi to San Diego?

Currently, August is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $286). Flying from Mississippi to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to SAN?

Find hourly flight availability from Mississippi to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated september 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to San Diego as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Mississippi?

    For a flight from Mississippi to San Diego, you will be flying into San Diego. San Diego (SAN) is just 2.6 mi from the center of the city.

  • How long is the flight from Mississippi to San Diego?

    Southwest, American Airlines, and Frontier can get you from Mississippi to San Diego in just under 6h 33m. Your travel time can differ by up to 23h 07m. Mississippi and San Diego are separated by a distance of 1563 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mississippi to San Diego one-way?

    One-way options have recently been found by users for as low as $90 on Southwest. Other airlines that offer cheap prices include United Airlines from $130 and Delta from $139 one-way.

  • What are the most popular routes from Mississippi to San Diego?

    The most popular flight routes from Mississippi to San Diego are Memphis - San Diego, Gulfport Biloxi Regional - San Diego and Baton Rouge Ryan - San Diego.

  • Can I find deals for flights from Mississippi to San Diego that include hotel bookings?

    Yes. In addition to deals on Mississippi to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to San Diego.

  • Can I find deals for business class flights from Mississippi to San Diego?

    Yes. Cheapflights offers flight deals from Mississippi to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $286). Flying from Mississippi to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
La Mesa
Poway
Lemon Grove
Coronado
Imperial Beach
National City
Alpine

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Mississippi to San Diego

Discover the top 4 airlines that operate flights from Mississippi to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated september 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$273Average$507FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$276Average$451FlexibilityNo cancel feeOn-time71%
DeltaCheapest$276Average$366FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$371Average$521FlexibilityNo cancel feeOn-time63%

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