$45+ Cheap flights from Mississippi to San Diego (SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SAN
May 5 — May 121
1 adult, Economy
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Find cheap flights from Mississippi to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mississippi to San Diego
Keep the following information in mind while searching for Mississippi to San Diego flight deals. Data was last updated April 30, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $138 (Booking.com) |
One-way from | $52 (FlightHub) |
Popular in | December |
Cheapest in | February |
Average price | $410 |
Find flight deals from Mississippi to San Diego
Cheapest flights from Mississippi to San DiegoExplore the most affordable flight options available from Mississippi to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.
Explore the most affordable flight options available from Mississippi to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.
This Booking.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/175:14 pmMEM - SAN
2 stops15h 59mSpirit Airlines
Mon 5/196:15 amSAN - MEM
1 stop11h 58mSpirit Airlines
Deal found 4/29![Spirit Airlines logo]()
$138
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/39:08 pmMEM - SAN
1 stop12h 05mMultiple Airlines
Fri 6/66:15 amSAN - MEM
1 stop12h 57mMultiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$158
This CheapOair deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/13:07 pmMEM - SAN
1 stop11h 06mFrontier
Sun 5/46:25 amSAN - MEM
1 stop5h 45mFrontier
Deal found 4/28![Frontier logo]()
$221
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/285:15 pmGPT - SAN
1 stop6h 05mUnited Airlines
Wed 6/411:50 amSAN - GPT
1 stop7h 44mUnited Airlines
Deal found 4/28![United Airlines logo]()
$247
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/27:49 pmGPT - SAN
1 stop6h 20mAmerican Airlines
Sat 8/92:48 pmSAN - GPT
1 stop6h 33mAmerican Airlines
Deal found 4/28![American Airlines logo]()
$277
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/23:30 pmGPT - SAN
1 stop8h 05mDelta
Tue 8/510:30 pmSAN - GPT
1 stop8h 33mDelta
Deal found 4/28![Delta logo]()
$282
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/279:10 amMOB - SAN
1 stop8h 36mDelta
Mon 6/92:00 pmSAN - MOB
1 stop7h 27mDelta
Deal found 4/28![Delta logo]()
$284
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/216:00 amMEM - SAN
1 stop7h 16mDelta
Tue 5/2710:30 pmSAN - MEM
1 stop7h 30mDelta
Deal found 4/28![Delta logo]()
$287
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/119:38 amBTR - SAN
1 stop7h 52mDelta
Sun 6/158:00 amSAN - BTR
1 stop8h 23mDelta
Deal found 4/29![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/212:25 pmMEM - SAN
2 stops7h 20mSouthwest
Sat 5/2410:30 amSAN - MEM
1 stop9h 40mSouthwest
Deal found 4/29![Southwest logo]()
$308
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/146:23 pmBTR - SAN
1 stop7h 20mAmerican Airlines
Sun 5/187:29 amSAN - BTR
1 stop6h 31mAmerican Airlines
Deal found 4/29![American Airlines logo]()
$332
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/139:20 amMOB - SAN
1 stop6h 37mUnited Airlines
Sat 5/176:15 amSAN - MOB
1 stop7h 57mUnited Airlines
Deal found 4/28![United Airlines logo]()
$334
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Mississippi to San Diego that are best for you.
Fly from
Mississippi
Fly to
San Diego
Route
Depart
Return
Price
MemphisSan Diego
MEM - SAN
MEMSAN
Memphis
Sat 5/17
5:14 pm-7:13 am
2 stops15h 59m
San Diego
Mon 5/19
6:15 am-8:13 pm
1 stop11h 58m
$138
MemphisSan Diego
MEM - SAN
MEMSAN
Memphis
Tue 6/3
9:08 pm-7:13 am
1 stop12h 05m
San Diego
Fri 6/6
6:15 am-9:12 pm
1 stop12h 57m
$158
GulfportSan Diego
GPT - SAN
GPTSAN
Gulfport Biloxi Regional
Wed 5/28
5:15 pm-9:20 pm
1 stop6h 05m
San Diego
Wed 6/4
11:50 am-9:34 pm
1 stop7h 44m
$247
GulfportSan Diego
GPT - SAN
GPTSAN
Gulfport Biloxi Regional
Sat 8/2
7:49 pm-12:09 am
1 stop6h 20m
San Diego
Sat 8/9
2:48 pm-11:21 pm
1 stop6h 33m
$277
GulfportSan Diego
GPT - SAN
GPTSAN
Gulfport Biloxi Regional
Sat 8/2
3:30 pm-9:35 pm
1 stop8h 05m
San Diego
Tue 8/5
10:30 pm-9:03 am
1 stop8h 33m
$282
MobileSan Diego
MOB - SAN
MOBSAN
Mobile
Tue 5/27
9:10 am-3:46 pm
1 stop8h 36m
San Diego
Mon 6/9
2:00 pm-11:27 pm
1 stop7h 27m
$284
MemphisSan Diego
MEM - SAN
MEMSAN
Memphis
Wed 5/21
6:00 am-11:16 am
1 stop7h 16m
San Diego
Tue 5/27
10:30 pm-8:00 am
1 stop7h 30m
$287
Baton RougeSan Diego
BTR - SAN
BTRSAN
Baton Rouge Ryan
Wed 6/11
9:38 am-3:30 pm
1 stop7h 52m
San Diego
Sun 6/15
8:00 am-6:23 pm
1 stop8h 23m
$289
MemphisSan Diego
MEM - SAN
MEMSAN
Memphis
Wed 5/21
2:25 pm-7:45 pm
2 stops7h 20m
San Diego
Sat 5/24
10:30 am-10:10 pm
1 stop9h 40m
$308
Baton RougeSan Diego
BTR - SAN
BTRSAN
Baton Rouge Ryan
Wed 5/14
6:23 pm-11:43 pm
1 stop7h 20m
San Diego
Sun 5/18
7:29 am-4:00 pm
1 stop6h 31m
$332
Showing 1-10 of 43 results
Best time to book a flight from Mississippi to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to San Diego
What is the cheapest month to book a flight from Mississippi to San Diego?
Currently, August is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $286). Flying from Mississippi to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MS to SAN?
Find hourly flight availability from Mississippi to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to San Diego as you normally would.
Rainfall in San Diego by month
Plan your trip to San Diego by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.
Temperature in San Diego by month
Plan your trip to San Diego by taking into account the average temperature totals by month.
If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated April 30, 2025.
To help decide which airline to fly from Mississippi to San Diego, see what other customers have to say about Breeze Airways, Southwest and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.6
Boarding
8.3
Food
6.7
Crew
8.8
Overall
8.1
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Boarding
8.3
Food
6.7
Crew
8.8
Overall
8.1
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Boarding
8.3
Food
6.7
Crew
8.8
Overall
8.1
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Boarding
8.3
Food
6.7
Crew
8.8
Overall
8.1
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Boarding
8.3
Food
6.7
Crew
8.8
Overall
8.1
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Boarding
8.3
Food
6.7
Crew
8.8
Overall
8.1
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Related info for your journey
Find useful and relevant information for your journey from Mississippi to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Mississippi?
Book flights to Mississippi if you plan to visit one of these locationsEl Cajon
Chula Vista
Lemon Grove
National City
Imperial Beach
La Mesa
Alpine
Poway
Santee
Coronado
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Mississippi to San Diego
See prices for flight routes from nearby airports that may be better suited for you.
Top 4 airlines flying from Mississippi to San Diego
Discover the top 4 airlines that operate flights from Mississippi to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$264 | Average$443 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$433 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$297 | Average$475 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$362 | Average$472 | FlexibilityNo cancel fee | On-time63% |