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$72+ Cheap flights from Iowa to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAN
nov. 29 — dic. 61
sáb. 11/29
sáb. 12/6
1 adult, Economy
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Cheap flight deals from Iowa to San Diego

Keep the following information in mind while searching for Iowa to San Diego flight deals. Data was last updated octubre 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$122
(Kiwi.com)

One-way from

$72
(Priceline)

Popular in

March

Cheapest in

June

Average price

$359
Provider with most accurate pricing for Des Moines-San Diego flight deals.
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Provider most trusted by Cheapflights users for Des Moines-San Diego flights.
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From Iowa to San Diego
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One-way flight from Iowa to San Diego
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Highest demand for flights based on searches. 16% potential increase in price ($71 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Iowa to San Diego

Cheapest flights from Iowa to San Diego
Explore the most affordable flight options available from Iowa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 30, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/87:58 pmDSM - SAN
1 stop6h 01mFrontier
vie. 12/126:34 amSAN - DSM
1 stop10h 29mFrontier
Deal found 10/29$122
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/232:35 pmDSM - SAN
1 stop11h 24mFrontier
dom. 12/281:06 pmSAN - DSM
2 stops28h 38mFrontier
Deal found 10/28$132
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/148:26 pmCID - SAN
1 stop15h 01mFrontier
mié. 11/191:37 pmSAN - CID
1 stop28h 09mFrontier
Deal found 10/29$146
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/157:58 pmDSM - SAN
1 stop28h 48mFrontier
dom. 12/214:47 pmSAN - DSM
1 stop24h 57mFrontier
Deal found 10/28$160
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/127:58 pmDSM - SAN
1 stop6h 01mFrontier
vie. 12/194:47 pmSAN - DSM
1 stop24h 57mFrontier
Deal found 10/28$163
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/157:58 pmDSM - SAN
1 stop6h 01mMultiple Airlines
mar. 12/231:06 pmSAN - DSM
1 stop23h 04mMultiple Airlines
Deal found 10/28$172
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/157:58 pmDSM - SAN
1 stop28h 48mFrontier
jue. 12/254:47 pmSAN - DSM
1 stop24h 57mFrontier
Deal found 10/28$173
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/122:24 pmOMA - SAN
1 stop6h 51mFrontier
sáb. 1/101:18 pmSAN - OMA
1 stop22h 31mFrontier
Deal found 10/30$174
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/102:32 pmDSM - SAN
1 stop23h 35mFrontier
jue. 11/136:00 pmSAN - DSM
1 stop17h 49mFrontier
Deal found 10/30$176
This Frontier deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/138:26 pmCID - SAN
1 stop5h 24mFrontier
jue. 11/206:49 amSAN - CID
1 stop10h 57mFrontier
Deal found 10/29$176
This Frontier deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/148:26 pmCID - SAN
1 stop5h 24mFrontier
jue. 11/206:49 amSAN - CID
1 stop10h 57mFrontier
Deal found 10/29$182
This Priceline deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/42:24 pmOMA - SAN
1 stop6h 51mFrontier
dom. 12/76:34 amSAN - OMA
1 stop4h 57mFrontier
Deal found 10/29$182

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
Use the filters below to find and compare flights from Iowa to San Diego that are best for you.

Fly from

Iowa

Fly to

San Diego

Route

Depart

Return

Price

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

jue. 12/18

8:42 pm-12:38 pm

2 stops17h 56m

San Diego

dom. 12/21

6:25 am-8:14 pm

1 stop11h 49m

$202

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

lun. 11/24

6:55 am-11:06 am

1 stop6h 11m

San Diego

jue. 11/27

6:30 am-4:54 pm

1 stop8h 24m

$233

Des MoinesSan Diego

DSM - SAN

DSMSAN

Des Moines

lun. 12/15

7:58 pm-11:59 pm

1 stop6h 01m

San Diego

dom. 12/21

1:06 pm-3:51 pm

2 stops24h 45m

$234

MolineSan Diego

MLI - SAN

MLISAN

Moline Quad-City

sáb. 1/10

3:58 pm-10:50 pm

1 stop8h 52m

San Diego

sáb. 1/24

7:10 am-3:27 pm

1 stop6h 17m

$251

MolineSan Diego

MLI - SAN

MLISAN

Moline Quad-City

sáb. 1/10

3:58 pm-10:50 pm

1 stop8h 52m

San Diego

mié. 1/21

6:20 am-3:27 pm

1 stop7h 07m

$251

MolineSan Diego

MLI - SAN

MLISAN

Moline Quad-City

sáb. 1/10

3:58 pm-10:50 pm

1 stop8h 52m

San Diego

mar. 1/20

1:19 pm-9:58 pm

1 stop6h 39m

$251

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

jue. 11/13

7:46 pm-11:50 pm

1 stop6h 04m

San Diego

lun. 11/17

6:41 am-8:06 pm

1 stop11h 25m

$252

MolineSan Diego

MLI - SAN

MLISAN

Moline Quad-City

mié. 1/7

7:31 am-1:08 pm

1 stop7h 37m

San Diego

dom. 1/11

7:10 am-3:27 pm

1 stop6h 17m

$270

Cedar RapidsSan Diego

CID - SAN

CIDSAN

Cedar Rapids

mié. 12/3

4:25 pm-8:42 pm

1 stop6h 17m

San Diego

sáb. 12/13

11:05 am-10:19 pm

1 stop9h 14m

$277

Cedar RapidsSan Diego

CID - SAN

CIDSAN

Cedar Rapids

jue. 12/4

4:25 pm-8:42 pm

1 stop6h 17m

San Diego

sáb. 12/13

12:24 pm-10:19 pm

1 stop7h 55m

$283

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 60 results
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Best time to book a flight from Iowa to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to San Diego

What is the cheapest month to book a flight from Iowa to San Diego?

Currently, August is the cheapest month in which you can book a flight from Iowa to San Diego (average of $100). Flying from Iowa to San Diego in December is currently the most expensive (average of $150). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to SAN?

Find hourly flight availability from Iowa to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 30, 2025.

It’s optimal to fly from Iowa to San Diego in the evening. By choosing this option you can save up to 28% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Iowa to San Diego?

Use this chart to determine the cheapest time to fly round-trip from Iowa to San Diego. Price data was last updated on December 8, 2024.

Travelers seeking maximum savings on their Iowa to San Diego flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Iowa to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Iowa?

    San Diego (SAN) is the airport you will fly into if you book a flight from Iowa to San Diego. It is only a 2.6 mi journey from San Diego (SAN) to San Diego’s city center.

  • How popular is this Iowa to San Diego flight route?

    Within the past month, 1 users have taken a look at flights from Iowa to San Diego.

  • How long is the flight from Iowa to San Diego?

    A quick flight from Iowa to San Diego can take about 6h 11m. Frontier provides one of the quickest options available for as low as $233. The distance from Iowa to San Diego is about 1310 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Iowa to San Diego one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $95. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Iowa to San Diego for a low price.

  • What are the most popular routes from Iowa to San Diego?

    The most popular route from Iowa to San Diego is Des Moines - San Diego. You may also consider Omaha Eppley Airfield - San Diego or Cedar Rapids - San Diego.

  • Can I find deals for flights from Iowa to San Diego that include hotel bookings?

    Yes. In addition to deals on Iowa to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to San Diego.

  • Can I find deals for business class flights from Iowa to San Diego?

    Yes. Cheapflights offers flight deals from Iowa to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Iowa to San Diego (average of $100). Flying from Iowa to San Diego in December is currently the most expensive (average of $150). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
National City

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Alternative routes for Iowa to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Iowa to San Diego

Discover the top 6 airlines that operate flights from Iowa to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$104Average$170FlexibilityNo cancel feeOn-time88%
FrontierCheapest$125Average$258FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$247Average$388FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$253Average$426FlexibilityNo cancel feeOn-time69%
DeltaCheapest$270Average$349FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$333Average$485FlexibilityNo cancel feeOn-time63%

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