HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Roanoke

$269+ Cheap flights from Des Moines to Roanoke (DSM - ROA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/20. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ROA
Aug 2 — Aug 91
Sun 8/2
Sun 8/9
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Roanoke with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Roanoke

Cheapest flights from Des Moines to Roanoke
Explore the most affordable flight options available from Des Moines to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2026.

This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:30 pm
DSM
-
ROA
1 stop5h 18m
American Airlines
Sat 10/31:57 pm
ROA
-
DSM
1 stop6h 54m
American Airlines
Deal found 6/29$309
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/141:41 pm
DSM
-
ROA
1 stop6h 39m
American Airlines
Sat 7/187:53 pm
ROA
-
DSM
1 stop5h 16m
American Airlines
Deal found 6/29$339
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:20 pm
DSM
-
ROA
1 stop4h 39m
United Airlines
Sat 8/295:50 pm
ROA
-
DSM
1 stop4h 33m
United Airlines
Deal found 6/30$389
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am
DSM
-
ROA
2 stops7h 14m
United Airlines
Sat 10/36:49 am
ROA
-
DSM
2 stops10h 31m
United Airlines
Deal found 6/29$398
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:00 am
DSM
-
ROA
2 stops8h 42m
American Airlines
Tue 7/212:51 pm
ROA
-
DSM
2 stops10h 10m
American Airlines
Deal found 7/1$409
This American Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:04 am
DSM
-
ROA
1 stop6h 38m
American Airlines
Sun 7/57:53 pm
ROA
-
DSM
1 stop5h 16m
American Airlines
Deal found 6/28$414
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:29 am
DSM
-
ROA
2 stops6h 25m
United Airlines
Sun 9/206:40 am
ROA
-
DSM
1 stop4h 51m
United Airlines
Deal found 6/30$424

Find flight deals from Des Moines to Roanoke

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Roanoke (ROA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$309
(American Airlines)

One-way from

$269
(Delta)

Popular in

July

Cheapest in

September

Average price

$750
Provider with most accurate pricing for Des Moines-Roanoke flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Roanoke flights.
Search Deals
From Des Moines to Roanoke
Search Deals
One-way flight from Des Moines to Roanoke
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($124 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($39 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2026.
Use the filters below to find and compare flights from Des Moines to Roanoke that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Wed 9/30

1:30 pm-7:48 pm

1 stop5h 18m

Roanoke

Sat 10/3

1:57 pm-7:51 pm

1 stop6h 54m

$309

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 7/17

11:23 am-5:11 pm

1 stop4h 48m

Roanoke

Tue 7/21

6:15 am-2:27 pm

2 stops9h 12m

$344
Quickest round-trip

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 8/25

3:20 pm-8:59 pm

1 stop4h 39m

Roanoke

Sat 8/29

5:50 pm-9:23 pm

1 stop4h 33m

$389

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 7/17

5:00 am-2:42 pm

2 stops8h 42m

Roanoke

Tue 7/21

2:51 pm-12:01 am

2 stops10h 10m

$409

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Sat 9/19

6:29 am-1:54 pm

2 stops6h 25m

Roanoke

Sun 9/20

6:40 am-10:31 am

1 stop4h 51m

$424

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 7/14

6:00 am-1:55 pm

2 stops6h 55m

Roanoke

Sat 7/18

10:30 am-9:22 pm

2 stops11h 52m

$438
Cheapest one-way
Quickest one-way

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 11/20

6:30 pm-12:23 am

1 stop4h 53m

$269

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 11/20

7:29 am-4:48 pm

2 stops8h 19m

$345

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Thu 7/9

3:24 pm-11:44 pm

2 stops7h 20m

$424

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Thu 7/9

3:42 pm-3:50 pm

3 stops23h 08m

$549

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/29

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Compare providers for flights from Des Moines to Roanoke

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Roanoke in July.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Roanoke flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Roanoke flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Roanoke flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Roanoke flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Roanoke flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Roanoke

Get insights into the airlines that provide service to Roanoke. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Roanoke. Reviews last updated July 3, 2026.
Read through reviews of airlines operating flights from Des Moines to Roanoke, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,764 reviews

Overall

7.1

Boarding

7.5

Entertainment

6.8

Comfort

7.2

Food

6.4

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!
American Airlines
7.1
Good
11,764 reviews
American Airlines
7.1
Good
11,764 reviews

Overall

7.1

Boarding

7.5

Entertainment

6.8

Comfort

7.2

Food

6.4

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Roanoke?

    Airlines like American Airlines and United Airlines fly from Des Moines to Roanoke in about 4h 48m. The time it takes to get you to your destination can typically vary by up to 30m. There are 784 mi between Des Moines and Roanoke. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Des Moines to Roanoke round-trip?

    Our cheapest airline available from Des Moines to Roanoke is American Airlines. Our recent data shows that you can find tickets from as low as $258 on this airline. American Airlines is currently priced 35% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Roanoke that include hotel bookings?

    Yes. In addition to deals on Des Moines to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Roanoke.

  • Can I find deals for business class flights from Des Moines to Roanoke?

    Yes. Cheapflights offers flight deals from Des Moines to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Salem
Radford
Blacksburg
Christiansburg

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Des Moines to Roanoke

Discover the top airline that operate flights from Des Moines to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$381FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.