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Roanoke

$249+ Cheap flights from Des Moines to Roanoke (DSM - ROA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/1. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ROA
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Des Moines to Roanoke

Cheapest flights from Des Moines to Roanoke
Explore the most affordable flight options available from Des Moines to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/183:44 pmDSM - ROA
1 stop21h 55mAllegiant Air
Mon 12/229:31 pmROA - DSM
1 stop17h 50mAllegiant Air
Deal found 12/3$327
This Kiwi.com deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/194:03 pmDSM - ROA
1 stop27h 36mAllegiant Air
Tue 12/239:40 pmROA - DSM
1 stop16h 15mAllegiant Air
Deal found 12/4$485
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:30 amDSM - ROA
2 stops10h 31mUnited Airlines
Mon 12/226:15 amROA - DSM
2 stops12h 50mUnited Airlines
Deal found 12/3$583
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:01 pmDSM - ROA
1 stop5h 58mAmerican Airlines
Sat 12/67:04 amROA - DSM
1 stop5h 38mAmerican Airlines
Deal found 12/3$634
This United Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:00 amDSM - ROA
1 stop11h 58mUnited Airlines
Tue 12/236:15 amROA - DSM
2 stops12h 50mUnited Airlines
Deal found 12/4$652

Find flight deals from Des Moines to Roanoke

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Roanoke (ROA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(Delta)

Popular in

January

Cheapest in

August

Average price

$278
Provider with most accurate pricing for Des Moines-Roanoke flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Roanoke flights.
Search Deals
From Des Moines to Roanoke
Search Deals
Highest demand for flights based on searches. 33% potential increase in price ($193 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($32 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Des Moines to Roanoke that are best for you.

Fly from

Des Moines

Fly to

Roanoke

Route

Depart

Return

Price

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Thu 1/1

3:27 pm-11:39 pm

1 stop7h 12m

Roanoke

Thu 1/8

8:50 am-3:44 pm

1 stop7h 54m

$249

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 2/10

8:00 am-2:46 pm

1 stop5h 46m

Roanoke

Sat 2/14

10:48 am-2:27 pm

1 stop4h 39m

$319

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Sun 2/22

9:00 am-2:22 pm

2 stops28h 22m

Roanoke

Thu 2/26

9:05 pm-6:24 pm

1 stop22h 19m

$383

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Sat 1/17

3:35 pm-9:11 pm

1 stop4h 36m

Roanoke

Wed 1/21

3:39 pm-9:50 pm

1 stop7h 11m

$449

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Sat 1/17

3:35 pm-9:11 pm

1 stop4h 36m

Roanoke

Sat 1/24

10:15 am-8:34 pm

2 stops11h 19m

$454

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Thu 12/18

3:44 pm-2:39 pm

1 stop21h 55m

Roanoke

Mon 12/22

9:31 pm-7:59 pm

2 stops47h 28m

$469

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 12/19

4:03 pm-8:39 pm

1 stop27h 36m

Roanoke

Tue 12/23

9:40 pm-12:55 pm

1 stop16h 15m

$485

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Sun 2/22

8:00 am-8:07 pm

2 stops11h 07m

Roanoke

Thu 2/26

10:15 am-9:51 pm

2 stops12h 36m

$487

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/4

Compare providers for flights from Des Moines to Roanoke

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Roanoke in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Roanoke flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Roanoke flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Roanoke flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Roanoke flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Roanoke flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Roanoke

What is the cheapest month to book a flight from Des Moines to Roanoke?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Roanoke (average of $248). Flying from Des Moines to Roanoke in February is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Roanoke

Get insights into the airlines that provide service to Roanoke. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Roanoke. Reviews last updated December 4, 2025.
Read through reviews of airlines operating flights from Des Moines to Roanoke, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,011 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Roanoke?

    Airlines like American Airlines, Delta, and United Airlines fly from Des Moines to Roanoke in about 5h 46m. The time it takes to get you to your destination can typically vary by up to 1h 26m. There are 784 mi between Des Moines and Roanoke. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Roanoke round-trip?

    Our cheapest airline available from Des Moines to Roanoke is Delta. Our recent data shows that you can find tickets from as low as $248 on this airline. An additional option worth looking into is American Airlines, starting at $258. Delta is currently priced 36% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Roanoke that include hotel bookings?

    Yes. In addition to deals on Des Moines to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Roanoke.

  • Can I find deals for business class flights from Des Moines to Roanoke?

    Yes. Cheapflights offers flight deals from Des Moines to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Roanoke?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Roanoke (average of $248). Flying from Des Moines to Roanoke in February is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Radford
Salem
Blacksburg
Christiansburg

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Alternative routes for Des Moines to Roanoke

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Des Moines to Roanoke

Discover the top 2 airlines that operate flights from Des Moines to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$323FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$258Average$363FlexibilityNo cancel feeOn-time71%

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