Panama City

$206+ Cheap flights from San Francisco (SFO) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — PTY
Jan 11 — Jan 181
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Find cheap flights from San Francisco to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from San Francisco to Panama City Tocumen Intl are usually found in October or August, booked 40 days in advance, depart on a Tuesday or Friday and return on a Monday

Cheap flight deals from San Francisco to Panama City

Cheapest flights from San Francisco to Panama City
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Priceline deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:10 amSFO - PTY
2 stops22h 20mAvianca
Sun 12/142:55 amPTY - SFO
2 stops21h 55mAvianca
Deal found 12/10$698
This Cheapflightsfares deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/131:35 amSFO - PTY
1 stop14h 20mAvianca
Tue 12/169:45 amPTY - SFO
2 stops15h 05mAvianca
Deal found 12/10$774
This Cheapflightsfares deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/131:35 amSFO - PTY
1 stop14h 20mAvianca
Mon 12/223:50 pmPTY - SFO
1 stop23h 10mAvianca
Deal found 12/10$791
This Cheapflightsfares deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/151:20 pmSFO - PTY
1 stop18h 10mAvianca
Tue 12/163:50 pmPTY - SFO
1 stop10h 30mAvianca
Deal found 12/10$793
This Expedia deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:25 amSFO - PTY
2 stops37h 15mMultiple Airlines
Tue 12/169:45 amPTY - SFO
2 stops15h 05mMultiple Airlines
Deal found 12/10$799
This Orbitz deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:07 pmSFO - PTY
2 stops22h 33mMultiple Airlines
Sat 12/272:55 amPTY - SFO
2 stops21h 55mMultiple Airlines
Deal found 12/10$827
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:07 pmSFO - PTY
2 stops17h 47mAmerican Airlines
Thu 1/84:50 pmPTY - SFO
2 stops22h 22mAmerican Airlines
Deal found 12/9$847
This Expedia deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:16 pmSFO - PTY
2 stops35h 14mMultiple Airlines
Tue 1/63:50 pmPTY - SFO
1 stop23h 10mMultiple Airlines
Deal found 12/11$855
This Expedia deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2311:07 pmSFO - PTY
2 stops38h 48mMultiple Airlines
Tue 1/63:50 pmPTY - SFO
1 stop23h 10mMultiple Airlines
Deal found 12/10$880

Find flight deals from San Francisco to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$637
(Copa Airlines)

One-way from

$206
(FlightHub)

Popular in

December

Cheapest in

October

Average price

$844

Good round-trip deal

$621 or less

Good one-way deal

$288 or less
Provider with most accurate pricing for San Francisco-Panama City Tocumen Intl flight deals.
Provider most trusted by Cheapflights users for San Francisco-Panama City Tocumen Intl flights.
From San Francisco to Panama City Tocumen Intl
One-way flight from San Francisco to Panama City Tocumen Intl
Highest demand for flights based on searches. 10% potential increase in price ($78 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
Average for round-trip flights in December 2025
Price to beat on a round-trip flight from San Francisco to Panama City Tocumen Intl.
Price to beat on a one-way flight from San Francisco to Panama City Tocumen Intl.

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.

Fly from

San Francisco

Fly to

Panama City

Route

Depart

Return

Price

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 2/10

12:42 am-10:46 am

Nonstop7h 04m

Panama City Tocumen Intl

Tue 2/17

6:27 pm-11:20 pm

Nonstop7h 53m

$637

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 2/10

12:42 am-10:46 am

Nonstop7h 04m

Panama City Tocumen Intl

Wed 2/18

6:27 pm-11:20 pm

Nonstop7h 53m

$637

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 2/3

12:42 am-10:46 am

Nonstop7h 04m

Panama City Tocumen Intl

Mon 2/23

6:27 pm-11:20 pm

Nonstop7h 53m

$652

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Thu 4/2

8:35 pm-5:35 am

Nonstop7h 00m

Panama City Tocumen Intl

Tue 4/21

5:53 pm-11:40 pm

Nonstop7h 47m

$652

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Thu 3/5

12:54 am-10:46 am

Nonstop6h 52m

Panama City Tocumen Intl

Fri 3/13

5:51 pm-11:40 pm

Nonstop7h 49m

$652

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Thu 4/2

8:35 pm-5:35 am

Nonstop7h 00m

Panama City Tocumen Intl

Tue 4/7

5:53 pm-11:40 pm

Nonstop7h 47m

$652

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 4/28

1:23 am-10:27 am

Nonstop7h 04m

Panama City Tocumen Intl

Sun 5/3

5:55 pm-11:40 pm

Nonstop7h 45m

$652

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Fri 5/15

1:12 am-10:27 am

Nonstop7h 15m

Panama City Tocumen Intl

Sun 5/24

12:38 pm-6:14 pm

Nonstop7h 36m

$667

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Thu 5/14

8:06 pm-5:35 am

Nonstop7h 29m

Panama City Tocumen Intl

Sun 5/17

5:55 pm-11:40 pm

Nonstop7h 45m

$667

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Thu 4/16

8:35 pm-5:35 am

Nonstop7h 00m

Panama City Tocumen Intl

Mon 4/20

5:53 pm-11:40 pm

Nonstop7h 47m

$667

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 17 results
1
2

Compare providers for flights from San Francisco to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Panama City in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy3 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Francisco-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Francisco-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Francisco-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Francisco-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Panama City

How far ahead should I book a flight from San Francisco to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Panama City. Price data was last updated on December 5, 2025.

The best time to book flights from San Francisco to Panama City is 40 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from San Francisco to Panama City?

Currently, June is the cheapest month in which you can book a flight from San Francisco to Panama City (average of $222). Flying from San Francisco to Panama City in November is currently the most expensive (average of $502). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to PTY?

Find hourly flight availability from San Francisco to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

It’s optimal to fly from San Francisco to Panama City at noon. By choosing this option you can save up to 56% on the cost of your flight, compared to a flight in the afternoon.

The best insider tips for San Francisco to Panama City flights

AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your San Francisco to Panama City trip
Airports
SFO

Save time by ordering meals for pickup through the SFO2Go program during busy times.

PTY

Use Uber for quick and cost-effective transport from PTY to Panama City, generally cheaper than taxis.

Our travel experts
Taryn White

Taryn White

Expert on PTY

Taryn White

Taryn White

Taryn White is a freelance travel writer, digital creator, and travel advisor who has visited nearly 100 countries and all 50 states. She’s familiar with many airports and enjoys beach hopping, boutique hotels, spa experiences, and exploring local culture. Her work has appeared in Travel + Leisure, Condé Nast Traveler, National Geographic, Smithsonian Magazine, AFAR, and more.

Read more
Harriet Baskas

Harriet Baskas

Expert on SFO

Harriet Baskas

Harriet Baskas

Harriet is an award-winning journalist who is happiest in an airport or an unusual museum. Her stories about airports, air travel, and the business of travel have appeared on NBC News, CNBC, USA TODAY, The Points Guy and other outlets. She is the creator of the StuckatTheAirport.com blog and the author of nine books. When not out on the road or exploring the latest airport amenities, she’s home in Seattle getting ready for the next adventure.

Read more

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated December 12, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines, and United Airlines from San Francisco to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airports do I use to fly from San Francisco to Panama City?

    To fly from San Francisco to Panama City, you need to book a flight from San Francisco (SFO) to Tocumen Intl (PTY). Nonstop flights to Panama City Tocumen Intl from San Francisco take 6h 53m on average. When it comes time to book airfare, you have a few options: there are 5 outbound flights from San Francisco to Tocumen Intl offered by 5 different airlines.

  • How popular is this San Francisco to Panama City flight route?

  • How long is the flight from San Francisco to Panama City?

    Departing from San Francisco to Panama City will take you 7h 04m. Airlines will cover a distance of 3318 mi. All flights are typically nonstop.

  • What are the cheapest airlines flying from San Francisco to Panama City round-trip?

    Our cheapest airline available from San Francisco to Panama City is Avianca. Our recent data shows that you can find tickets from as low as $280 on this airline. Additional options worth looking into are Delta and Copa Airlines, starting at $387 and $498 round-trip. You may be able to fly from San Francisco to Panama City for 56% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from San Francisco to Panama City one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $201. Copa Airlines flights start at $354 while deals on United Airlines start at $399 one-way.

  • What are the most reliable airlines from San Francisco to Panama City?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from San Francisco to Panama City on time: Copa Airlines (86%), United Airlines (86%), EVA Air (84%).

  • What are the cheapest flights from San Francisco to Panama City?

    While on average a flight from San Francisco to Panama City is generally $1,016, our data shows the cheapest flight currently is $209. When looking at the most popular route, (San Francisco - Panama City Tocumen Intl), you can expect to pay $556 for that flight.

  • Where are the most common layover locations when flying from San Francisco to Panama City?

  • What are some popular things to do or see while on a layover in Houston?

    Houston travelers tend to visit Space Center Houston, House of Blues Houston, and Revention Music Center more than anywhere else. Space Center Houston, House of Blues Houston, and Revention Music Center can be accessed by traveling approximately 33.5 mi, 16.1 mi, and 15.5 mi, respectively from Houston George Bush Intcntl. Those landing in Houston looking to spend some time exploring during their layover can rent a car for about $38 per day.

  • Where are the least popular layover locations for San Francisco to Panama City flights?

  • Can I find deals for flights from San Francisco to Panama City that include hotel bookings?

    Yes. In addition to deals on San Francisco to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Panama City.

  • Can I find deals for business class flights from San Francisco to Panama City?

    Yes. Cheapflights offers flight deals from San Francisco to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Panama City?

    Currently, June is the cheapest month in which you can book a flight from San Francisco to Panama City (average of $222). Flying from San Francisco to Panama City in November is currently the most expensive (average of $502). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 5 airlines flying from San Francisco to Panama City

Discover the top 5 airlines that operate flights from San Francisco to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$387Average$547FlexibilityNo cancel feeOn-timeN/A
AviancaCheapest$434Average$504FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$503Average$651FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$533Average$739FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$579Average$895FlexibilityNo cancel feeOn-time71%

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