Panama City

$209+ Cheap flights from San Francisco (SFO) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — PTY
Aug 3 — Aug 101
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Cheapflights Tip: The best prices from San Francisco to Panama City Tocumen Intl are usually found in August or September, booked 26 days in advance, depart on a Tuesday or Wednesday and return on a Thursday

Cheap flight deals from San Francisco to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$499
(Cheapflightsfares)

One-way from

$209
(Justfly.com)

Popular in

December

Cheapest in

August

Average price

$616

Good round-trip deal

$506 or less

Good one-way deal

$290 or less
From San Francisco to Panama City Tocumen Intl
One-way flight from San Francisco to Panama City Tocumen Intl
Highest demand for flights based on searches. 15% potential increase in price ($118 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($37 potential savings vs. average RT price).
Average for round-trip flights in July 2025
Price to beat on a round-trip flight from San Francisco to Panama City Tocumen Intl.
Price to beat on a one-way flight from San Francisco to Panama City Tocumen Intl.

Find flight deals from San Francisco to Panama City

Cheapest flights from San Francisco to Panama City
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/52:20 pmSFO - PTY
1 stop18h 05mAvianca
Mon 9/158:10 pmPTY - SFO
1 stop18h 25mAvianca
Deal found 7/28$499
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/412:43 amSFO - PTY
1 stop13h 24mUnited Airlines
Sun 12/143:35 pmPTY - SFO
Nonstop7h 54mUnited Airlines
Deal found 7/29$508
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/49:38 pmSFO - PTY
1 stop13h 17mDelta
Fri 10/172:21 pmPTY - SFO
1 stop11h 35mDelta
Deal found 7/26$518
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/187:45 pmSFO - PTY
2 stops16h 46mAmerican Airlines
Thu 9/253:31 pmPTY - SFO
1 stop23h 34mAmerican Airlines
Deal found 7/28$520
This Copa Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/261:30 amSFO - PTY
Nonstop7h 11mCopa Airlines
Thu 9/45:50 pmPTY - SFO
Nonstop7h 35mCopa Airlines
Deal found 7/28$534
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/147:10 amSFO - PTY
1 stop20h 15mMultiple Airlines
Thu 9/1810:05 pmPTY - SFO
2 stops16h 30mMultiple Airlines
Deal found 7/28$558

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.

Fly from

San Francisco

Fly to

Panama City

Route

Depart

Return

Price

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 8/12

2:20 pm-10:25 am

1 stop18h 05m

Panama City Tocumen Intl

Sun 8/17

3:20 am-10:45 pm

2 stops21h 25m

$499

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Sat 10/4

9:38 pm-12:55 pm

1 stop13h 17m

Panama City Tocumen Intl

Fri 10/17

2:21 pm-11:56 pm

1 stop11h 35m

$518

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Fri 9/12

10:55 am-8:10 pm

Nonstop7h 15m

Panama City Tocumen Intl

Fri 9/19

3:35 pm-9:10 pm

Nonstop7h 35m

$519

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Thu 9/18

7:45 pm-2:31 pm

2 stops16h 46m

Panama City Tocumen Intl

Thu 9/25

3:31 pm-1:05 pm

1 stop23h 34m

$520

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 8/26

1:30 am-10:41 am

Nonstop7h 11m

Panama City Tocumen Intl

Thu 9/4

5:50 pm-11:25 pm

Nonstop7h 35m

$534

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Sun 9/14

7:10 am-5:25 am

1 stop20h 15m

Panama City Tocumen Intl

Thu 9/18

10:05 pm-12:35 pm

2 stops16h 30m

$558

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 8/12

12:05 am-10:25 am

1 stop8h 20m

$209

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Wed 8/27

8:48 am-8:55 am

3 stops22h 07m

$285

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Wed 10/22

10:55 am-8:10 pm

Nonstop7h 15m

$400

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 8/26

1:30 am-10:41 am

Nonstop7h 11m

$604

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

The best insider tips for San Francisco to Panama City flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your San Francisco to Panama City trip
Airports
SFO

Save time by ordering meals for pickup through the SFO2Go program during busy times.

Read more about SFOby Harriet Baskas
PTY

Use Uber for quick and cost-effective transport from PTY to Panama City, generally cheaper than taxis.

Read more about PTYby Taryn White
Our travel experts
Taryn White

Taryn White

Expert on PTY

Taryn White

Taryn White

Taryn White is a freelance travel writer, digital creator, and travel advisor who has visited nearly 100 countries and all 50 states. She’s familiar with many airports and enjoys beach hopping, boutique hotels, spa experiences, and exploring local culture. Her work has appeared in Travel + Leisure, Condé Nast Traveler, National Geographic, Smithsonian Magazine, AFAR, and more.

Read more
Harriet Baskas

Harriet Baskas

Expert on SFO

Harriet Baskas

Harriet Baskas

Harriet is an award-winning journalist who is happiest in an airport or an unusual museum. Her stories about airports, air travel, and the business of travel have appeared on NBC News, CNBC, USA TODAY, The Points Guy and other outlets. She is the creator of the StuckatTheAirport.com blog and the author of nine books. When not out on the road or exploring the latest airport amenities, she’s home in Seattle getting ready for the next adventure.

Read more

Best time to book a flight from San Francisco to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Panama City

How far ahead should I book a flight from San Francisco to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Panama City. Price data was last updated on July 25, 2025.

The best time to book flights from San Francisco to Panama City is 26 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from San Francisco to Panama City?

Currently, October is the cheapest month in which you can book a flight from San Francisco to Panama City (average of $478). Flying from San Francisco to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to PTY?

Find hourly flight availability from San Francisco to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

It’s optimal to fly from San Francisco to Panama City at noon. By choosing this option you can save up to 34% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from San Francisco to Panama City?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Panama City. Price data was last updated on July 27, 2025.

Travelers seeking maximum savings on their San Francisco to Panama City flight should consider departing on Saturday at noon when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from San Francisco to Panama City

Explore weekly flight availability from San Francisco to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 29, 2025.

The most flights from SFO to PTY are scheduled on a Monday (5 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 29, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines, and United Airlines from San Francisco to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good
8.0
Very good

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airports do I use to fly from San Francisco to Panama City?

    To fly from San Francisco to Panama City, you need to book a flight from San Francisco (SFO) to Tocumen Intl (PTY). Nonstop flights to Panama City Tocumen Intl from San Francisco take 7h 04m on average. When it comes time to book airfare, you have a few options: there are 3 outbound flights from San Francisco to Tocumen Intl offered by 5 different airlines.

  • How popular is this San Francisco to Panama City flight route?

  • What are the cheapest airlines flying from San Francisco to Panama City round-trip?

    Our cheapest airline available from San Francisco to Panama City is Avianca. Our recent data shows that you can find tickets from as low as $499 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $518 and $519 round-trip. You may be able to fly from San Francisco to Panama City for 24% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from San Francisco to Panama City one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $209. United Airlines flights start at $400 while deals on Copa Airlines start at $604 one-way.

  • What are the most reliable airlines from San Francisco to Panama City?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from San Francisco to Panama City on time: EVA Air (95%), Copa Airlines (91%), United Airlines (86%).

  • What are the cheapest flights from San Francisco to Panama City?

    While on average a flight from San Francisco to Panama City is generally $1,422, our data shows the cheapest flight currently is $209. When looking at the most popular route, (San Francisco - Panama City Tocumen Intl), you can expect to pay $494 for that flight.

  • Can I find deals for flights from San Francisco to Panama City that include hotel bookings?

    Yes. In addition to deals on San Francisco to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Panama City.

  • Can I find deals for business class flights from San Francisco to Panama City?

    Yes. Cheapflights offers flight deals from San Francisco to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Panama City?

    Currently, October is the cheapest month in which you can book a flight from San Francisco to Panama City (average of $478). Flying from San Francisco to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 5 airlines flying from San Francisco to Panama City

Discover the top 5 airlines that operate flights from San Francisco to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$387Average$611FlexibilityNo cancel feeOn-timeN/A
AviancaCheapest$400Average$581FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$513Average$648FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$539Average$712FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$544Average$590FlexibilityNo cancel feeOn-time71%

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