How popular is this San Francisco to Panama City flight route?

This flight path from San Francisco to Panama City Tocumen Intl was viewed by 141 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

What are the cheapest airlines flying from San Francisco to Panama City round-trip?

Our cheapest airline available from San Francisco to Panama City is Avianca. Our recent data shows that you can find tickets from as low as $482 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $518 and $519 round-trip. You may be able to fly from San Francisco to Panama City for 28% less than the average price by searching for these airlines.

What are the cheapest airlines to fly from San Francisco to Panama City one-way?

To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $213. United Airlines flights start at $525 while deals on Copa Airlines start at $579 one-way.

What are the cheapest flights from San Francisco to Panama City?

While on average a flight from San Francisco to Panama City is generally $1,311, our data shows the cheapest flight currently is $211. When looking at the most popular route, (San Francisco - Panama City Tocumen Intl), you can expect to pay $486 for that flight.

What are the most reliable airlines from San Francisco to Panama City?

Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from San Francisco to Panama City on time: EVA Air (90%), United Airlines (90%), Copa Airlines (89%).

What are the most popular airlines that fly from San Francisco to Panama City?

The most popular airlines flying from San Francisco to Panama City are American Airlines, Avianca and Copa Airlines. Something to consider prior to booking your flight.

What is the cheapest day to fly round-trip from San Francisco to Panama City?

Flights from San Francisco to Panama City are found to be more expensive on Friday. This shouldn't discourage you from searching as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Panama City.

How far in advance should I book a flight from San Francisco to Panama City?

Travelers have found it’s best to book a flight 41 days in advance to save up to 60% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 41 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from San Francisco to Panama City 1-2 weeks in advance for as low as $608, or $1,095 for flights within the next 24 hours.

What is the cheapest month to fly from San Francisco to Panama City?

Due to multiple factors, expect to potentially pay more when booking in December. For low rates, August can be a great choice for travel to Panama City. Flights to Panama City from San Francisco in August are about $672 on average during August, but can be found for as low as $477.

Most accurate provider : When it comes to deals on San Francisco-Panama City flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on San Francisco-Panama City flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from San Francisco-Panama City flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on San Francisco-Panama City flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airports do I use to fly from San Francisco to Panama City?

To fly from San Francisco to Panama City, you need to book a flight from San Francisco (SFO) to Tocumen Intl (PTY). Nonstop flights to Panama City Tocumen Intl from San Francisco take 7h 02m on average. When it comes time to book airfare, you have a few options: there are 3 outbound flights from San Francisco to Tocumen Intl offered by 5 different airlines.

Can I find deals for flights from San Francisco to Panama City that include hotel bookings?

Yes. In addition to deals on San Francisco to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from San Francisco to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Panama City.

Can I find deals for business class flights from San Francisco to Panama City?

Yes. Cheapflights offers flight deals from San Francisco to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$213+ Flights from San Francisco to Panama City

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from San Francisco to Panama City Tocumen Intl are usually found in August or September, booked 40 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from San Francisco to Panama City

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$482 (Avianca)
One-way from	$213 (Cheapflightsfares)
Popular in	December
Cheapest in	August
Average price	$647
Good round-trip deal	$582 or less
Good one-way deal	$255 or less

Provider with most accurate pricing for San Francisco-Panama City Tocumen Intl flight deals.

Search Deals

Provider most trusted by Cheapflights users for San Francisco-Panama City Tocumen Intl flights.

Search Deals

From San Francisco to Panama City Tocumen Intl

Search Deals

One-way flight from San Francisco to Panama City Tocumen Intl

Search Deals

Highest demand for flights based on searches. 16% potential increase in price ($134 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 6% potential price decrease ($40 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

Search Deals

Price to beat on a round-trip flight from San Francisco to Panama City Tocumen Intl.

Search Deals

Price to beat on a one-way flight from San Francisco to Panama City Tocumen Intl.

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Find flight deals from San Francisco to Panama City

Cheapest flights from San Francisco to Panama City
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

Thu 6/122:30 amSFO - PTY

2 stops16h 40mAvianca

Fri 6/208:10 pmPTY - SFO

1 stop18h 25mAvianca

Deal found 4/28

$482

Mon 9/110:30 pmSFO - PTY

1 stop12h 24mDelta

Mon 9/222:14 pmPTY - SFO

1 stop12h 32mDelta

Deal found 4/27

$518

Wed 6/1110:55 amSFO - PTY

Nonstop7h 15mUnited Airlines

Thu 6/193:15 pmPTY - SFO

Nonstop7h 43mUnited Airlines

Deal found 4/27

$519

Tue 5/271:37 amSFO - PTY

Nonstop7h 04mCopa Airlines

Sun 6/85:50 pmPTY - SFO

Nonstop7h 50mCopa Airlines

Deal found 4/27

$601

Sun 11/1612:31 amSFO - PTY

2 stops11h 49mAmerican Airlines

Thu 12/42:45 pmPTY - SFO

1 stop11h 14mAmerican Airlines

Deal found 4/27

$648

Thu 6/122:30 amSFO - PTY

1 stop12h 21mMultiple Airlines

Wed 6/183:40 pmPTY - SFO

1 stop9h 05mMultiple Airlines

Deal found 4/28

$649

Best flights from San Francisco to Panama City
Discover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2025.

Thu 6/122:30 amSFO - PTY

2 stops16h 40mAvianca

Fri 6/208:10 pmPTY - SFO

1 stop18h 25mAvianca

Deal found 4/28

$482

Thu 6/1911:59 pmSFO - PTY

1 stop17h 31mDelta

Thu 6/262:23 pmPTY - SFO

1 stop12h 31mDelta

Deal found 4/27

$518

Wed 6/1110:55 amSFO - PTY

Nonstop7h 15mUnited Airlines

Wed 6/183:15 pmPTY - SFO

Nonstop7h 43mUnited Airlines

Deal found 4/27

$519

Tue 5/271:37 amSFO - PTY

Nonstop7h 04mCopa Airlines

Sun 6/85:50 pmPTY - SFO

Nonstop7h 50mCopa Airlines

Deal found 4/27

$601

Sun 6/156:47 pmSFO - PTY

2 stops17h 38mAmerican Airlines

Sat 6/211:50 pmPTY - SFO

2 stops21h 54mAmerican Airlines

Deal found 4/28

$648

Thu 6/122:30 amSFO - PTY

1 stop12h 21mMultiple Airlines

Wed 6/183:40 pmPTY - SFO

1 stop9h 05mMultiple Airlines

Deal found 4/28

$649

Last-minute flights from San Francisco to Panama City
Discover last-minute flight deals from San Francisco to Panama City. Data last updated April 29, 2025 and is based on user searches.

Tue 5/612:05 amSFO - PTY

1 stop8h 20mAvianca

Thu 5/83:40 pmPTY - SFO

1 stop9h 05mAvianca

Deal found 4/28

$486

Tue 5/61:37 amSFO - PTY

Nonstop7h 04mCopa Airlines

Thu 5/85:50 pmPTY - SFO

Nonstop7h 50mCopa Airlines

Deal found 4/28

$981

Tue 5/612:05 amSFO - PTY

1 stop8h 20mMultiple Airlines

Thu 5/85:50 pmPTY - SFO

Nonstop7h 50mMultiple Airlines

Deal found 4/28

$1,592

Fri 5/912:05 amSFO - PTY

1 stop8h 20mAvianca

Mon 5/193:40 pmPTY - SFO

1 stop9h 05mAvianca

Deal found 4/27

$485

Mon 5/125:49 pmSFO - PTY

2 stops16h 30mAmerican Airlines

Fri 5/161:20 pmPTY - SFO

2 stops22h 15mAmerican Airlines

Deal found 4/26

$1,438

Sat 5/2410:55 amSFO - PTY

Nonstop7h 15mUnited Airlines

Sun 6/13:15 pmPTY - SFO

Nonstop7h 43mUnited Airlines

Deal found 4/26

$534

Sat 5/246:09 pmSFO - PTY

3 stops25h 01mMultiple Airlines

Sun 5/253:20 amPTY - SFO

2 stops35h 15mMultiple Airlines

Deal found 4/26

$868

Tue 5/271:37 amSFO - PTY

Nonstop7h 04mCopa Airlines

Sun 6/85:50 pmPTY - SFO

Nonstop7h 50mCopa Airlines

Deal found 4/27

$601

One-way flights from San Francisco to Panama City
Search for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated April 29, 2025.

Mon 5/1212:05 amSFO - PTY

1 stop12h 40mAvianca

Deal found 4/28

$213

Wed 6/411:33 pmSFO - PTY

3 stops32h 37mMultiple Airlines

Deal found 4/27

$242

Sat 6/2110:55 amSFO - PTY

Nonstop7h 15mUnited Airlines

Deal found 4/28

$525

Sat 6/141:37 amSFO - PTY

Nonstop7h 04mCopa Airlines

Deal found 4/27

$579

Tue 5/131:35 pmSFO - PTY

2 stops20h 44mAmerican Airlines

Deal found 4/27

$1,215

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Thu 6/12

2:30 am-9:10 pm

2 stops16h 40m

Panama City Tocumen Intl

Fri 6/20

8:10 pm-12:35 pm

1 stop18h 25m

$482

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Mon 9/1

10:30 pm-12:54 pm

1 stop12h 24m

Panama City Tocumen Intl

Mon 9/22

2:14 pm-12:46 am

1 stop12h 32m

$518

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Wed 6/11

10:55 am-8:10 pm

Nonstop7h 15m

Panama City Tocumen Intl

Wed 6/18

3:15 pm-8:58 pm

Nonstop7h 43m

$519

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 5/27

1:37 am-10:41 am

Nonstop7h 04m

Panama City Tocumen Intl

Sun 6/8

5:50 pm-11:40 pm

Nonstop7h 50m

$601

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Sun 6/15

6:47 pm-2:25 pm

2 stops17h 38m

Panama City Tocumen Intl

Sat 6/21

1:50 pm-9:44 am

2 stops21h 54m

$648

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Thu 6/12

2:30 am-4:51 pm

1 stop12h 21m

Panama City Tocumen Intl

Wed 6/18

3:40 pm-10:45 pm

1 stop9h 05m

$649

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Mon 5/12

12:05 am-4:30 pm

2 stops14h 25m

$213

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Wed 6/4

11:33 pm-10:10 am

3 stops32h 37m

$242

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Sat 6/21

10:55 am-8:10 pm

Nonstop7h 15m

$525

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Sat 6/14

1:37 am-10:41 am

Nonstop7h 04m

$579

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 11 results

Compare providers for flights from San Francisco to Panama City

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Panama City in April.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*2 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy3 stars	Trust Score*3 stars
Cheapflightsfares	Price Accuracy3 stars	Trust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on San Francisco-Panama City flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on San Francisco-Panama City flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from San Francisco-Panama City flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on San Francisco-Panama City flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

The best insider tips for San Francisco to Panama City flights

Cheapflights partnered with top experts to bring you the best recommendations for your San Francisco to Panama City trip

Airports

SFO

Save time by using the AirTrain Red Line to quickly navigate between terminals at SFO, especially during busy travel times.

PTY

Use Uber for a quick and cost-effective ride from PTY to Panama City, offering more convenience than taxis or public transport.

Our travel experts

Taryn White

Expert on PTY

Harriet Baskas

Expert on SFO

Best time to book a flight from San Francisco to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Panama City

How far ahead should I book a flight from San Francisco to Panama City?

The best time to book flights from San Francisco to Panama City is 40 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from San Francisco to Panama City?

Currently, October is the cheapest month in which you can book a flight from San Francisco to Panama City (average of $478). Flying from San Francisco to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to PTY?

It’s optimal to fly from San Francisco to Panama City at noon. By choosing this option you can save up to 40% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from San Francisco to Panama City?

Travelers seeking maximum savings on their San Francisco to Panama City flight should consider departing on Saturday at noon when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from San Francisco to Panama City

The most flights from SFO to PTY are scheduled on a Wednesday (5 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (3 on average).

Rainfall in Panama City by month

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

Temperature in Panama City by month

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama City

Peruse reviews from past customers who have flown with Delta, Copa Airlines and United Airlines from San Francisco to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,929 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,929 reviews

Delta

8.0

Very good

7,929 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines

7.5

Good

1,410 reviews

Delta

8.0

Very good

7,929 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

8,696 reviews

Delta

8.0

Very good

7,929 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,929 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Avianca

6.7

Okay

2,317 reviews

Delta

8.0

Very good

7,929 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What airports do I use to fly from San Francisco to Panama City?
To fly from San Francisco to Panama City, you need to book a flight from San Francisco (SFO) to Tocumen Intl (PTY). Nonstop flights to Panama City Tocumen Intl from San Francisco take 7h 02m on average. When it comes time to book airfare, you have a few options: there are 3 outbound flights from San Francisco to Tocumen Intl offered by 5 different airlines.
How popular is this San Francisco to Panama City flight route?
This flight path from San Francisco to Panama City Tocumen Intl was viewed by 141 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
What are the cheapest airlines flying from San Francisco to Panama City round-trip?
Our cheapest airline available from San Francisco to Panama City is Avianca. Our recent data shows that you can find tickets from as low as $482 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $518 and $519 round-trip. You may be able to fly from San Francisco to Panama City for 28% less than the average price by searching for these airlines.
What are the cheapest airlines to fly from San Francisco to Panama City one-way?
To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $213. United Airlines flights start at $525 while deals on Copa Airlines start at $579 one-way.
What are the most reliable airlines from San Francisco to Panama City?
Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from San Francisco to Panama City on time: EVA Air (90%), United Airlines (90%), Copa Airlines (89%).
What are the cheapest flights from San Francisco to Panama City?
While on average a flight from San Francisco to Panama City is generally $1,311, our data shows the cheapest flight currently is $211. When looking at the most popular route, (San Francisco - Panama City Tocumen Intl), you can expect to pay $486 for that flight.
Can I find deals for flights from San Francisco to Panama City that include hotel bookings?
Yes. In addition to deals on San Francisco to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from San Francisco to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Panama City.
Can I find deals for business class flights from San Francisco to Panama City?
Yes. Cheapflights offers flight deals from San Francisco to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from San Francisco to Panama City?
Currently, October is the cheapest month in which you can book a flight from San Francisco to Panama City (average of $478). Flying from San Francisco to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for San Francisco to Panama City

Complete your trip

Panama City car rentals

Panama City Tocumen Intl Airport car rentals

Casco Viejo car rentals

San Francisco car rentals

Bella Vista car rentals

Calidonia car rentals

Ancón car rentals

Santa Ana car rentals

Bethania car rentals

Parque Lefevre car rentals

Juan Diaz car rentals

Pueblo Nuevo car rentals

Other flights to Panama City

Top 5 airlines flying from San Francisco to Panama City

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$387	Average$732	FlexibilityNo cancel fee	On-timeN/A
Avianca	Cheapest$400	Average$639	FlexibilityNo cancel fee	On-time71%
Copa Airlines	Cheapest$477	Average$647	FlexibilityNo cancel fee	On-time70%
United Airlines	Cheapest$540	Average$719	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$544	Average$596	FlexibilityNo cancel fee	On-time71%

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$213+ Cheap flights from San Francisco (SFO) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from San Francisco to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from San Francisco to Panama City Tocumen Intl are usually found in August or September, booked 40 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from San Francisco to Panama City

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from San Francisco to Panama City

Cheapest flights from San Francisco to Panama CityExplore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.

Compare providers for flights from San Francisco to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Panama City in April.

The best insider tips for San Francisco to Panama City flights

Cheapflights partnered with top experts to bring you the best recommendations for your San Francisco to Panama City trip

Airports

SFO

PTY

Our travel experts

Best time to book a flight from San Francisco to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Panama City

How far ahead should I book a flight from San Francisco to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Panama City. Price data was last updated on April 25, 2025.

What is the cheapest month to book a flight from San Francisco to Panama City?

What is the cheapest time of day to fly from SFO to PTY?

Find hourly flight availability from San Francisco to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

What is the cheapest day to fly from San Francisco to Panama City?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Panama City. Price data was last updated on March 30, 2025.

Weekly flight availability from San Francisco to Panama City

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

Reviews of airlines servicing Panama City

Peruse reviews from past customers who have flown with Delta, Copa Airlines and United Airlines from San Francisco to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from San Francisco to Panama City?

How popular is this San Francisco to Panama City flight route?

What are the cheapest airlines flying from San Francisco to Panama City round-trip?

What are the cheapest airlines to fly from San Francisco to Panama City one-way?

What are the most reliable airlines from San Francisco to Panama City?

What are the cheapest flights from San Francisco to Panama City?

Can I find deals for flights from San Francisco to Panama City that include hotel bookings?

How can I find direct flights from San Francisco to Panama City?

Can I find deals for business class flights from San Francisco to Panama City?

What is the cheapest month to book a flight from San Francisco to Panama City?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for San Francisco to Panama City

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Cheapest flights from San Francisco to Panama City
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.