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Panama City

$193+ Cheap flights from San Francisco (SFO) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — PTY
Feb 25 — Mar 41
Wed 2/25
Wed 3/4
1 adult, Economy
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Find cheap flights from San Francisco to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from San Francisco to Panama City Tocumen Intl are usually found in October or August, booked 8 days in advance, depart on a Tuesday or Monday and return on a Tuesday

Cheap flight deals from San Francisco to Panama City

Cheapest flights from San Francisco to Panama City
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 26, 2026.

This Avianca deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/311:10 pm
SFO
-
PTY
1 stop16h 45m
Avianca
Tue 2/177:50 pm
PTY
-
SFO
1 stop19h 10m
Avianca
Deal found 1/26$495
This Avianca deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/22:30 am
SFO
-
PTY
1 stop21h 25m
Avianca
Thu 4/95:30 am
PTY
-
SFO
1 stop20h 25m
Avianca
Deal found 1/25$502
This Priceline deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1312:10 am
SFO
-
PTY
1 stop8h 20m
Avianca
Mon 3/167:50 pm
PTY
-
SFO
1 stop19h 10m
Avianca
Deal found 1/23$505
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1011:10 pm
SFO
-
PTY
1 stop8h 20m
Avianca
Tue 2/179:45 am
PTY
-
SFO
2 stops15h 05m
Avianca
Deal found 1/24$509
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1512:10 am
SFO
-
PTY
1 stop8h 20m
Avianca
Sat 3/213:50 pm
PTY
-
SFO
1 stop9h 50m
Avianca
Deal found 1/24$510
This Priceline deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/212:35 am
SFO
-
PTY
1 stop14h 20m
Avianca
Sun 3/293:50 pm
PTY
-
SFO
1 stop23h 00m
Avianca
Deal found 1/25$512
This Priceline deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/221:20 pm
SFO
-
PTY
2 stops24h 35m
Avianca
Sun 3/17:50 pm
PTY
-
SFO
1 stop19h 10m
Avianca
Deal found 1/25$513
This Avianca deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2911:10 pm
SFO
-
PTY
1 stop8h 20m
Avianca
Sun 2/17:50 pm
PTY
-
SFO
1 stop19h 10m
Avianca
Deal found 1/24$515
This Priceline deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/22:30 am
SFO
-
PTY
1 stop21h 25m
Avianca
Mon 4/133:50 pm
PTY
-
SFO
1 stop23h 00m
Avianca
Deal found 1/26$519
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1512:10 am
SFO
-
PTY
1 stop8h 20m
Avianca
Sun 3/225:50 pm
PTY
-
SFO
2 stops21h 10m
Avianca
Deal found 1/26$522
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1512:10 am
SFO
-
PTY
1 stop8h 20m
Avianca
Wed 3/259:45 am
PTY
-
SFO
2 stops15h 05m
Avianca
Deal found 1/26$525
This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/2711:10 pm
SFO
-
PTY
1 stop8h 20m
Avianca
Sun 2/85:50 pm
PTY
-
SFO
2 stops21h 10m
Avianca
Deal found 1/23$528

Find flight deals from San Francisco to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$495
(Priceline)

One-way from

$193
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$658

Good round-trip deal

$536 or less

Good one-way deal

$228 or less
Provider with most accurate pricing for San Francisco-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Francisco-Panama City Tocumen Intl flights.
Search Deals
From San Francisco to Panama City Tocumen Intl
Search Deals
One-way flight from San Francisco to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($75 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from San Francisco to Panama City Tocumen Intl.
Search Deals
Price to beat on a one-way flight from San Francisco to Panama City Tocumen Intl.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.

Fly from

San Francisco

Fly to

Panama City

Route

Depart

Return

Price

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Sun 4/26

1:23 am-10:27 am

Nonstop7h 04m

Panama City Tocumen Intl

Fri 5/1

5:55 pm-11:40 pm

Nonstop7h 45m

$700

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Mon 4/27

1:23 am-10:27 am

Nonstop7h 04m

Panama City Tocumen Intl

Sun 5/3

5:55 pm-11:40 pm

Nonstop7h 45m

$715

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 3/24

1:54 am-10:46 am

Nonstop6h 52m

Panama City Tocumen Intl

Sun 4/5

5:53 pm-11:40 pm

Nonstop7h 47m

$715

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 3/31

1:23 am-10:27 am

Nonstop7h 04m

Panama City Tocumen Intl

Mon 4/20

5:53 pm-11:40 pm

Nonstop7h 47m

$715

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Mon 3/23

1:54 am-10:46 am

Nonstop6h 52m

Panama City Tocumen Intl

Sun 4/5

5:53 pm-11:40 pm

Nonstop7h 47m

$715

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Sun 5/10

8:06 pm-5:35 am

Nonstop7h 29m

Panama City Tocumen Intl

Thu 5/14

5:55 pm-11:40 pm

Nonstop7h 45m

$715

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Sun 4/12

1:23 am-10:27 am

Nonstop7h 04m

Panama City Tocumen Intl

Sat 4/18

5:53 pm-11:40 pm

Nonstop7h 47m

$715

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 4/28

1:23 am-10:27 am

Nonstop7h 04m

Panama City Tocumen Intl

Sun 5/3

5:55 pm-11:40 pm

Nonstop7h 45m

$715

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Sat 3/14

1:54 am-10:46 am

Nonstop6h 52m

Panama City Tocumen Intl

Wed 4/15

5:53 pm-11:40 pm

Nonstop7h 47m

$715

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Wed 4/22

1:23 am-10:27 am

Nonstop7h 04m

Panama City Tocumen Intl

Thu 5/7

5:55 pm-11:40 pm

Nonstop7h 45m

$715

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/24

Showing 1-10 of 21 results
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Compare providers for flights from San Francisco to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Panama City in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy3 starsTrust Score*2 stars
CheapfaremartPrice Accuracy-Trust Score*1 star
JustAirTicketPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Francisco-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Francisco-Panama City flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Panama City

How far ahead should I book a flight from San Francisco to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Panama City. Price data was last updated on January 23, 2026.

The best time to book flights from San Francisco to Panama City is 8 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from San Francisco to Panama City?

Currently, June is the cheapest month in which you can book a flight from San Francisco to Panama City (average of $222). Flying from San Francisco to Panama City in November is currently the most expensive (average of $502). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to PTY?

Find hourly flight availability from San Francisco to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 26, 2026.

When flying from San Francisco to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

The best insider tips for San Francisco to Panama City flights

AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your San Francisco to Panama City trip
Our travel experts
Taryn White

Taryn White

Expert on PTY

Taryn White is a freelance travel writer, digital creator, and travel advisor who has visited nearly 100 countries and all 50 states. She’s familiar with many airports and enjoys beach hopping, boutique hotels, spa experiences, and exploring local culture. Her work has appeared in Travel + Leisure, Condé Nast Traveler, National Geographic, Smithsonian Magazine, AFAR, and more.

Read more
Harriet Baskas

Harriet Baskas

Expert on SFO

Harriet is an award-winning journalist who is happiest in an airport or an unusual museum. Her stories about airports, air travel, and the business of travel have appeared on NBC News, CNBC, USA TODAY, The Points Guy and other outlets. She is the creator of the StuckatTheAirport.com blog and the author of nine books. When not out on the road or exploring the latest airport amenities, she’s home in Seattle getting ready for the next adventure.

Read more

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated January 26, 2026.
Read reviews from past customers who have flown Delta, Copa Airlines, and United Airlines from San Francisco to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,113 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
7.9
Good
8,113 reviews
Delta
7.9
Good
8,113 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,558 reviews
Delta
7.9
Good
8,113 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
9,198 reviews
Delta
7.9
Good
8,113 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.6
Okay
2,491 reviews
Delta
7.9
Good
8,113 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from San Francisco to Panama City?

    To fly from San Francisco to Panama City, you need to book a flight from San Francisco (SFO) to Tocumen Intl (PTY). Nonstop flights to Panama City Tocumen Intl from San Francisco take 6h 52m on average. When it comes time to book airfare, you have a few options: there are 3 outbound flights from San Francisco to Tocumen Intl offered by 4 different airlines.

  • How popular is this San Francisco to Panama City flight route?

    This flight path from San Francisco to Panama City Tocumen Intl was viewed by 93 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from San Francisco to Panama City?

    Departing from San Francisco to Panama City will take you 7h 04m. Airlines will cover a distance of 3318 mi. All flights are typically nonstop.

  • What are the cheapest airlines flying from San Francisco to Panama City round-trip?

    Our cheapest airline available from San Francisco to Panama City is Avianca. Our recent data shows that you can find tickets from as low as $234 on this airline. Additional options worth looking into are Delta and Copa Airlines, starting at $387 and $437 round-trip. You may be able to fly from San Francisco to Panama City for 64% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from San Francisco to Panama City one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $199. Copa Airlines flights start at $366 while deals on United Airlines start at $399 one-way.

  • What are the most reliable airlines from San Francisco to Panama City?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from San Francisco to Panama City on time: Copa Airlines (80%), United Airlines (80%), EVA Air (75%).

  • What are the cheapest flights from San Francisco to Panama City?

    While on average a flight from San Francisco to Panama City is generally $1,128, our data shows the cheapest flight currently is $209. When looking at the most popular route, (San Francisco - Panama City Tocumen Intl), you can expect to pay $485 for that flight.

  • Where are the most common layover locations when flying from San Francisco to Panama City?

    The most popular layover on flights from San Francisco to Panama City is San Salvador.

  • Where are the least popular layover locations for San Francisco to Panama City flights?

    Of the flights from San Francisco to Panama City that have layovers, the fewest flights stop in Houston.

  • Can I find deals for flights from San Francisco to Panama City that include hotel bookings?

    Yes. In addition to deals on San Francisco to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Panama City.

  • Can I find deals for business class flights from San Francisco to Panama City?

    Yes. Cheapflights offers flight deals from San Francisco to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Panama City?

    Currently, June is the cheapest month in which you can book a flight from San Francisco to Panama City (average of $222). Flying from San Francisco to Panama City in November is currently the most expensive (average of $502). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from San Francisco to Panama City

Discover the top 4 airlines that operate flights from San Francisco to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$234Average$496FlexibilityNo cancel feeOn-time71%
DeltaCheapest$387Average$587FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$437Average$667FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$533Average$740FlexibilityNo cancel feeOn-time69%

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