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Panama City

$428+ Cheap flights from Madrid, Spain (MAD) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — PTY
Jul 5 — Jul 121
Sat 7/5
Sat 7/12
1 adult, Economy
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Cheapflights Tip: The best prices from Madrid Barajas to Panama City Tocumen Intl are usually found in March or September, booked 88 days in advance, depart on a Friday or Monday and return on a Tuesday

Cheap flight deals from Madrid to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 30, 2025.

Round-trip from

$692
(United Airlines)

One-way from

$428
(FlightHub)

Popular in

December

Cheapest in

March

Average price

$747

Good round-trip deal

$1,262 or less

Good one-way deal

$644 or less
From Madrid Barajas to Panama City Tocumen Intl
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One-way flight from Madrid Barajas to Panama City Tocumen Intl
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Highest demand for flights based on searches. 7% potential increase in price ($68 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Price to beat on a round-trip flight from Madrid Barajas to Panama City Tocumen Intl.
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Price to beat on a one-way flight from Madrid Barajas to Panama City Tocumen Intl.
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Find flight deals from Madrid to Panama City

Cheapest flights from Madrid to Panama City
Explore the most affordable flight options available from Madrid to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1111:15 amMAD - PTY
2 stops38h 22mUnited Airlines
Thu 9/43:30 pmPTY - MAD
2 stops57h 35mUnited Airlines
Deal found 6/30$692
This KLM deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/3010:20 amMAD - PTY
1 stop37h 30mKLM
Wed 10/86:50 pmPTY - MAD
1 stop21h 35mKLM
Deal found 6/28$696
This Air Europa deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/253:05 pmMAD - PTY
Nonstop10h 35mAir Europa
Sun 9/288:25 pmPTY - MAD
Nonstop9h 50mAir Europa
Deal found 6/29$715
This KLM deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1110:05 amMAD - PTY
1 stop14h 40mMultiple Airlines
Sat 10/186:50 pmPTY - MAD
1 stop31h 45mMultiple Airlines
Deal found 6/29$741
This Avianca deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/23:25 pmMAD - PTY
1 stop29h 15mAvianca
Wed 11/123:19 amPTY - MAD
1 stop28h 06mAvianca
Deal found 6/29$746
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2110:05 amMAD - PTY
1 stop33h 50mDelta
Sat 9/272:10 pmPTY - MAD
2 stops34h 40mDelta
Deal found 6/29$762

Cheapflights Fare Finder

Customize your flight search to find flights from Madrid to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
Use the filters below to find and compare flights from Madrid to Panama City that are best for you.

Fly from

Madrid

Fly to

Panama City

Route

Depart

Return

Price

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Fri 7/11

11:15 am-6:37 pm

2 stops38h 22m

Panama City Tocumen Intl

Thu 9/4

3:30 pm-8:05 am

2 stops57h 35m

$692

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Tue 9/30

10:20 am-4:50 pm

1 stop37h 30m

Panama City Tocumen Intl

Wed 10/8

6:50 pm-11:25 pm

1 stop21h 35m

$696

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Thu 9/25

3:05 pm-6:40 pm

Nonstop10h 35m

Panama City Tocumen Intl

Mon 9/29

8:25 pm-1:15 pm

Nonstop9h 50m

$715

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Sat 10/11

10:05 am-5:45 pm

1 stop14h 40m

Panama City Tocumen Intl

Sat 10/18

6:50 pm-9:35 am

1 stop31h 45m

$741

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Sun 11/2

3:25 pm-2:40 pm

1 stop29h 15m

Panama City Tocumen Intl

Wed 11/12

3:19 am-1:25 pm

1 stop28h 06m

$746

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Sun 9/21

10:05 am-12:55 pm

1 stop33h 50m

Panama City Tocumen Intl

Sat 9/27

2:10 pm-7:50 am

2 stops34h 40m

$762

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Thu 9/11

1:30 am-10:10 am

1 stop15h 40m

$428

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Fri 9/12

9:55 pm-8:11 am

2 stops41h 16m

$506

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Fri 9/12

3:05 pm-6:40 pm

Nonstop10h 35m

$586

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Fri 9/12

12:00 pm-3:40 pm

Nonstop10h 40m

$626

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Showing 1-10 of 11 results
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The best insider tips for Madrid to Panama City flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your Madrid to Panama City trip
Airports
MAD

Many airlines at MAD offer automated kiosks for quick check-in, including Iberia. Security lines can be crowded but move quickly.

Read more about MADby Lori Zaino
PTY

At PTY, Uber is often the fastest and less expensive transport option to Panama City, compared to taxis.

Read more about PTYby Taryn White
Our travel experts
Lori Zaino

Lori Zaino

Expert on MAD

Lori Zaino

Lori Zaino

US-born but now based in Spain, Lori's visited 60 countries---and written about them for publications like CNN, Forbes, The Points Guy, NBC, and TripAdvisor. She loves combining affordable adventures with luxury travel experiences and feels equally at home salsa dancing in Colombia, sipping wine in a French castle, or backpacking through Malaysia.

Read more
Taryn White

Taryn White

Expert on PTY

Taryn White

Taryn White

Taryn White is a freelance travel writer, digital creator, and travel advisor who has visited nearly 100 countries and all 50 states. She’s familiar with many airports and enjoys beach hopping, boutique hotels, spa experiences, and exploring local culture. Her work has appeared in Travel + Leisure, Condé Nast Traveler, National Geographic, Smithsonian Magazine, AFAR, and more.

Read more

Best time to book a flight from Madrid to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Panama City

How far ahead should I book a flight from Madrid to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Madrid to Panama City. Price data was last updated on June 27, 2025.

The price you pay for your flight from Madrid to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 88 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Madrid to Panama City?

Currently, October is the cheapest month in which you can book a flight from Madrid to Panama City (average of $478). Flying from Madrid to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to PTY?

Find hourly flight availability from Madrid to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 30, 2025.

It’s optimal to fly from Madrid to Panama City in the morning. By choosing this option you can save up to 7% on the cost of your flight, compared to a flight at noon.

Weekly flight availability from Madrid to Panama City

Explore weekly flight availability from Madrid to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 30, 2025.

The most flights from MAD to PTY are scheduled on a Monday (9 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (4 on average).

How much does it cost to fly round-trip from Madrid to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated June 30, 2025.
Get a feel of what it's like to fly with Delta, KLM, and United Airlines from Madrid to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Peter,Oct 2023

MSP - GEG

The amount of carry on is put of control. We were in group 3 boarding and there was no room in upper storage for our 1 bag (between 2 people) Just because we can’t afford to up grade our seats… $2000 more. We get penaltized. Make us feel less than
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Peter,Oct 2023

MSP - GEG

The amount of carry on is put of control. We were in group 3 boarding and there was no room in upper storage for our 1 bag (between 2 people) Just because we can’t afford to up grade our seats… $2000 more. We get penaltized. Make us feel less than
KLM
7.8
Good
1,365 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Peter,Oct 2023

MSP - GEG

The amount of carry on is put of control. We were in group 3 boarding and there was no room in upper storage for our 1 bag (between 2 people) Just because we can’t afford to up grade our seats… $2000 more. We get penaltized. Make us feel less than
United Airlines
7.4
Good
8,852 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Peter,Oct 2023

MSP - GEG

The amount of carry on is put of control. We were in group 3 boarding and there was no room in upper storage for our 1 bag (between 2 people) Just because we can’t afford to up grade our seats… $2000 more. We get penaltized. Make us feel less than
Turkish Airlines
7.3
Good
3,884 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Peter,Oct 2023

MSP - GEG

The amount of carry on is put of control. We were in group 3 boarding and there was no room in upper storage for our 1 bag (between 2 people) Just because we can’t afford to up grade our seats… $2000 more. We get penaltized. Make us feel less than
Air Europa
6.9
Okay
540 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Peter,Oct 2023

MSP - GEG

The amount of carry on is put of control. We were in group 3 boarding and there was no room in upper storage for our 1 bag (between 2 people) Just because we can’t afford to up grade our seats… $2000 more. We get penaltized. Make us feel less than

Related info for your journey

Find useful and relevant information for your journey from Madrid to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Madrid to Panama City?

    To fly from Madrid to Panama City, you need to book a flight from Barajas (MAD) to Tocumen Intl (PTY). Nonstop flights to Panama City Tocumen Intl from Madrid Barajas take 10h 35m on average. When it comes time to book airfare, you have a few options: there are 5 outbound flights from Barajas to Tocumen Intl offered by 3 different airlines.

  • How popular is this Madrid to Panama City flight route?

    The Madrid Barajas to Panama City Tocumen Intl flight path was viewed by 4 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Madrid to Panama City round-trip?

    United Airlines, at $692, was found to be the cheapest airline from Madrid to Panama City.Alternate airlines to your destination round-trip include KLM and Air Europa. United Airlines is 13% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Madrid to Panama City one-way?

    For one-way options, check prices for Avianca. According to our data, you can fly for as low as $428. Users have also found prices from $586 and $626 on Air Europa and Iberia, respectively.

  • What are the most reliable airlines from Madrid to Panama City?

    Consider Pascan (100%), Qatar Airways (79%) or Iberia (79%) when booking your flight. These represent the most reliable airlines when flying from Madrid to Panama City.

  • What are the cheapest flights from Madrid to Panama City?

    The cheapest flight price from Madrid to Panama City is $490. On average you can expect to pay $1,027. The most popular route, (Madrid Barajas - Panama City Tocumen Intl), can usually be booked for $779.

  • Can I find deals for flights from Madrid to Panama City that include hotel bookings?

    Yes. In addition to deals on Madrid to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Panama City.

  • Can I find deals for business class flights from Madrid to Panama City?

    Yes. Cheapflights offers flight deals from Madrid to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Madrid to Panama City (average of $478). Flying from Madrid to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Madrid to Panama City

Discover the top 3 airlines that operate flights from Madrid to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$582Average$1,069FlexibilityNo cancel feeOn-time71%
Air EuropaCheapest$630Average$879FlexibilityNo cancel feeOn-time83%
IberiaCheapest$644Average$790FlexibilityNo cancel feeOn-time77%

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