$99+ Cheap flights from St. Louis (STL) to Panama City Beach, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/5. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PNS
Mar 8 — Mar 151
1 adult, Economy
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Find cheap flights from St. Louis to Panama City Beach with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Lambert-St Louis to Panama City Beach are usually found in October or December, booked 44 days in advance, depart on a Wednesday or Tuesday and return on a Thursday
Cheap flight deals from St. Louis to Panama City Beach
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to Panama City BeachExplore the most affordable flight options available from St. Louis to Panama City Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 6, 2026.
Explore the most affordable flight options available from St. Louis to Panama City Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 6, 2026.
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:59 pm
STL
- ECP
1 stop4h 05m
Delta
Fri 4/174:31 pm
ECP
- STL
1 stop4h 48m
Delta
Deal found 2/5![Delta logo]()
$197
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:47 pm
STL
- ECP
1 stop3h 52m
Delta
Tue 2/245:00 pm
ECP
- STL
1 stop6h 36m
Delta
Deal found 2/5![Delta logo]()
$205
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/211:30 pm
STL
- ECP
2 stops10h 19m
American Airlines
Wed 2/2510:20 am
ECP
- STL
1 stop6h 38m
American Airlines
Deal found 2/3![American Airlines logo]()
$210
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:53 pm
STL
- ECP
1 stop4h 53m
American Airlines
Tue 4/1411:43 am
ECP
- STL
1 stop5h 20m
American Airlines
Deal found 2/5![American Airlines logo]()
$243
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:53 pm
STL
- ECP
1 stop4h 53m
American Airlines
Sat 4/253:38 pm
ECP
- STL
1 stop5h 47m
American Airlines
Deal found 2/4![American Airlines logo]()
$254
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
STL
- ECP
1 stop6h 44m
American Airlines
Sat 2/283:00 pm
ECP
- STL
1 stop6h 12m
American Airlines
Deal found 2/4![American Airlines logo]()
$258
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:50 pm
STL
- ECP
1 stop4h 22m
Delta
Mon 5/116:47 pm
ECP
- STL
1 stop5h 12m
Delta
Deal found 2/4![Delta logo]()
$264
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/83:37 pm
STL
- ECP
1 stop5h 42m
American Airlines
Wed 2/1112:03 pm
ECP
- STL
1 stop6h 31m
American Airlines
Deal found 2/3![American Airlines logo]()
$267
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:37 am
STL
- ECP
1 stop4h 47m
American Airlines
Fri 3/137:19 am
ECP
- STL
1 stop5h 24m
American Airlines
Deal found 2/3![American Airlines logo]()
$268
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:25 pm
STL
- ECP
2 stops10h 27m
American Airlines
Thu 4/167:21 am
ECP
- STL
1 stop6h 01m
American Airlines
Deal found 2/5![American Airlines logo]()
$272
Best flights from St. Louis to Panama City BeachDiscover carefully curated flight deals from St. Louis to Panama City Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 6, 2026.
Discover carefully curated flight deals from St. Louis to Panama City Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 6, 2026.
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:59 pm
STL
- ECP
1 stop4h 05m
Delta
Fri 4/174:31 pm
ECP
- STL
1 stop4h 48m
Delta
Deal found 2/5![Delta logo]()
$197
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
STL
- ECP
1 stop6h 44m
American Airlines
Sat 2/287:19 am
ECP
- STL
2 stops9h 54m
American Airlines
Deal found 2/4![American Airlines logo]()
$263
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:41 pm
STL
- ECP
1 stop4h 41m
Delta
Wed 4/155:10 pm
ECP
- STL
1 stop6h 24m
Delta
Deal found 2/5![Delta logo]()
$197
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:59 am
STL
- ECP
1 stop5h 27m
Delta
Wed 4/155:10 pm
ECP
- STL
1 stop6h 24m
Delta
Deal found 2/5![Delta logo]()
$197
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:41 pm
STL
- ECP
1 stop6h 31m
Delta
Sat 4/185:10 pm
ECP
- STL
1 stop6h 24m
Delta
Deal found 2/5![Delta logo]()
$197
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:02 pm
STL
- ECP
1 stop4h 58m
Delta
Fri 4/174:31 pm
ECP
- STL
1 stop4h 48m
Delta
Deal found 2/5![Delta logo]()
$197
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:25 pm
STL
- ECP
2 stops10h 27m
American Airlines
Wed 4/157:21 am
ECP
- STL
2 stops9h 20m
American Airlines
Deal found 2/5![American Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:01 pm
STL
- ECP
1 stop5h 38m
Delta
Wed 2/255:00 pm
ECP
- STL
1 stop6h 36m
Delta
Deal found 2/3![Delta logo]()
$205
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:47 pm
STL
- ECP
1 stop3h 52m
Delta
Tue 2/245:00 pm
ECP
- STL
1 stop6h 36m
Delta
Deal found 2/4![Delta logo]()
$205
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:50 pm
STL
- ECP
1 stop4h 22m
Delta
Mon 5/116:47 pm
ECP
- STL
1 stop5h 12m
Delta
Deal found 2/4![Delta logo]()
$264
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:00 pm
STL
- ECP
1 stop6h 04m
Delta
Thu 4/165:49 am
ECP
- STL
1 stop4h 45m
Delta
Deal found 2/5![Delta logo]()
$278
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:41 pm
STL
- ECP
1 stop6h 31m
Delta
Mon 4/207:05 am
ECP
- STL
1 stop4h 51m
Delta
Deal found 2/5![Delta logo]()
$278
Last-minute flights from St. Louis to Panama City BeachDiscover last-minute flight deals from St. Louis to Panama City Beach. Data last updated February 6, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Panama City Beach. Data last updated February 6, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/83:37 pm
STL
- ECP
1 stop5h 42m
American Airlines
Wed 2/1112:03 pm
ECP
- STL
1 stop6h 31m
American Airlines
Deal found 2/3![American Airlines logo]()
$267
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:47 pm
STL
- ECP
1 stop3h 52m
Delta
Tue 2/245:00 pm
ECP
- STL
1 stop6h 36m
Delta
Deal found 2/5![Delta logo]()
$205
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:57 pm
STL
- ECP
1 stop4h 52m
American Airlines
Tue 2/242:00 pm
ECP
- STL
2 stops9h 48m
American Airlines
Deal found 2/4![American Airlines logo]()
$283
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/211:30 pm
STL
- ECP
2 stops10h 19m
American Airlines
Wed 2/2510:20 am
ECP
- STL
1 stop6h 38m
American Airlines
Deal found 2/3![American Airlines logo]()
$210
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/211:30 pm
STL
- ECP
2 stops10h 19m
American Airlines
Sat 2/283:00 pm
ECP
- STL
1 stop6h 12m
American Airlines
Deal found 2/4![American Airlines logo]()
$277
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
STL
- ECP
1 stop6h 44m
American Airlines
Sat 2/283:00 pm
ECP
- STL
1 stop6h 12m
American Airlines
Deal found 2/4![American Airlines logo]()
$258
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:47 pm
STL
- ECP
1 stop3h 52m
Delta
Mon 3/96:00 am
ECP
- STL
1 stop5h 09m
Delta
Deal found 2/3![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:37 am
STL
- ECP
1 stop4h 47m
American Airlines
Fri 3/137:19 am
ECP
- STL
1 stop5h 24m
American Airlines
Deal found 2/3![American Airlines logo]()
$268
This Southwest deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:40 am
STL
- ECP
1 stop10h 40m
Southwest
Mon 3/304:30 pm
ECP
- STL
1 stop7h 15m
Southwest
Deal found 2/4![Southwest logo]()
$294
One-way flights from St. Louis to Panama City BeachSearch for one-way flight options from St. Louis to Panama City Beach. Find affordable one-way fares based on user searches. Data last updated February 6, 2026.
Search for one-way flight options from St. Louis to Panama City Beach. Find affordable one-way fares based on user searches. Data last updated February 6, 2026.
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:59 pm
STL
- ECP
1 stop4h 05m
Delta
Deal found 2/5![Delta logo]()
$99
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:10 am
STL
- ECP
1 stop4h 15m
Delta
Deal found 2/4![Delta logo]()
$103
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:25 pm
STL
- ECP
2 stops10h 27m
American Airlines
Deal found 2/6![American Airlines logo]()
$104
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:06 am
STL
- ECP
2 stops7h 24m
American Airlines
Deal found 2/5![American Airlines logo]()
$108
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:57 pm
STL
- ECP
1 stop4h 52m
American Airlines
Deal found 2/4![American Airlines logo]()
$134
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:53 pm
STL
- ECP
1 stop4h 56m
American Airlines
Deal found 2/4![American Airlines logo]()
$138
This Southwest deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:40 pm
STL
- ECP
Nonstop1h 45m
Southwest
Deal found 2/6![Southwest logo]()
$140
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:00 am
STL
- ECP
2 stops10h 04m
American Airlines
Deal found 2/4![American Airlines logo]()
$143
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:52 pm
STL
- ECP
1 stop4h 25m
American Airlines
Deal found 2/2![American Airlines logo]()
$145
This Southwest deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/410:40 am
STL
- ECP
Nonstop1h 50m
Southwest
Deal found 2/5![Southwest logo]()
$161
Find flight deals from St. Louis to Panama City Beach
Keep the following information in mind while searching for St. Louis to Panama City Beach flight deals. Data was last updated February 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $197 (Delta) |
One-way from | $99 (Delta) |
Popular in | February |
Cheapest in | October |
Average price | $437 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Panama City Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 6, 2026.
Use the filters below to find and compare flights from St. Louis to Panama City Beach that are best for you.
Fly from
St. Louis
Fly to
Panama City Beach
Route
Depart
Return
Price
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Fri 4/10
6:59 pm-11:04 pm
1 stop4h 05m
Panama City NW Florida Beaches
Fri 4/17
4:31 pm-9:19 pm
1 stop4h 48m
$197
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Mon 4/13
4:41 pm-9:22 pm
1 stop4h 41m
Panama City NW Florida Beaches
Wed 4/15
5:10 pm-11:34 pm
1 stop6h 24m
$197
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Tue 4/14
9:59 am-3:26 pm
1 stop5h 27m
Panama City NW Florida Beaches
Wed 4/15
5:10 pm-11:34 pm
1 stop6h 24m
$197
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Mon 4/13
4:41 pm-11:12 pm
1 stop6h 31m
Panama City NW Florida Beaches
Sat 4/18
5:10 pm-11:34 pm
1 stop6h 24m
$197
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Tue 4/14
1:02 pm-6:00 pm
1 stop4h 58m
Panama City NW Florida Beaches
Fri 4/17
4:31 pm-9:19 pm
1 stop4h 48m
$197
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Sat 2/21
5:01 pm-10:39 pm
1 stop5h 38m
Panama City NW Florida Beaches
Wed 2/25
5:00 pm-11:36 pm
1 stop6h 36m
$205
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Fri 2/20
6:47 pm-10:39 pm
1 stop3h 52m
Panama City NW Florida Beaches
Tue 2/24
5:00 pm-11:36 pm
1 stop6h 36m
$205
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Tue 2/24
6:00 am-12:44 pm
1 stop6h 44m
Panama City NW Florida Beaches
Sat 2/28
7:19 am-5:13 pm
2 stops9h 54m
$263
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Wed 5/6
6:50 pm-11:12 pm
1 stop4h 22m
Panama City NW Florida Beaches
Mon 5/11
6:47 pm-11:59 pm
1 stop5h 12m
$264
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Tue 4/14
12:25 pm-10:52 pm
2 stops10h 27m
Panama City NW Florida Beaches
Wed 4/15
7:21 am-4:41 pm
2 stops9h 20m
$278
Showing 1-10 of 20 results
Best time to book a flight from St. Louis to Panama City Beach
Have a flexible travel schedule? Discover the best time to fly to Panama City Beach from St. Louis with our price prediction graph.
STL-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Panama City Beach
STL-PA9
STL-ECP
How far ahead should I book a flight from St. Louis to Panama City Beach?
Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Panama City Beach. Price data was last updated on January 30, 2026.
The best time to book flights from St. Louis to Panama City Beach is 44 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from St. Louis to Panama City Beach?
Currently, July is the cheapest month in which you can book a flight from St. Louis to Panama City Beach (average of $85). Flying from St. Louis to Panama City Beach in October is currently the most expensive (average of $110). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from STL to PA9?
Find hourly flight availability from St. Louis to Panama City Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 6, 2026.
It’s optimal to fly from St. Louis to Panama City Beach in the afternoon. By choosing this option you can save up to 11% on the cost of your flight, compared to a flight in the evening.
Reviews of airlines servicing Panama City Beach
Get insights into the airlines that provide service to Panama City Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City Beach. Reviews last updated February 6, 2026.
Read through reviews of airlines operating flights from St. Louis to Panama City Beach, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Panama City Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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St. Louis and Panama City Beach flights
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Top 4 airlines flying from St. Louis to Panama City Beach
Discover the top 4 airlines that operate flights from St. Louis to Panama City Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$82 | Average$158 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$165 | Average$350 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$185 | Average$382 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$414 | FlexibilityNo cancel fee | On-time63% |