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Panama City Beach

$145+ Cheap flights from St. Louis (STL) to Panama City Beach, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PNS
Jan 23 — Jan 301
Fri 1/23
Fri 1/30
1 adult, Economy
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Cheapflights Tip: The best prices from Lambert-St Louis to Panama City Beach are usually found in October or December, booked 88 days in advance, depart on a Wednesday or Tuesday and return on a Tuesday

Cheap flight deals from St. Louis to Panama City Beach

Cheapest flights from St. Louis to Panama City Beach
Explore the most affordable flight options available from St. Louis to Panama City Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 24, 2025.

This American Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:16 amSTL - ECP
1 stop6h 54mAmerican Airlines
Sat 12/274:09 pmECP - STL
1 stop7h 47mAmerican Airlines
Deal found 12/22$351
This Delta deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:13 pmSTL - ECP
1 stop5h 49mDelta
Thu 1/85:14 pmECP - STL
1 stop6h 25mDelta
Deal found 12/24$355
This United Airlines deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:30 amSTL - ECP
2 stops9h 40mUnited Airlines
Thu 1/84:54 pmECP - STL
1 stop5h 06mUnited Airlines
Deal found 12/24$361
This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:30 amSTL - ECP
1 stop6h 57mUnited Airlines
Mon 12/292:55 pmECP - STL
1 stop7h 00mUnited Airlines
Deal found 12/22$367
This American Airlines deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:00 amSTL - ECP
1 stop5h 37mAmerican Airlines
Sun 12/2812:40 pmECP - STL
1 stop6h 42mAmerican Airlines
Deal found 12/23$383
This Southwest deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2410:15 amSTL - ECP
1 stop5h 35mSouthwest
Sun 12/286:35 pmECP - STL
1 stop5h 30mSouthwest
Deal found 12/23$431
This Delta deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:13 pmSTL - ECP
1 stop5h 49mDelta
Fri 1/27:02 pmECP - STL
1 stop4h 40mDelta
Deal found 12/23$445
This Southwest deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:30 amSTL - ECP
1 stop10h 35mSouthwest
Sun 1/46:35 pmECP - STL
1 stop5h 30mSouthwest
Deal found 12/24$464
This Delta deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:13 pmSTL - ECP
1 stop5h 49mDelta
Sun 1/48:02 amECP - STL
1 stop6h 28mDelta
Deal found 12/23$475

Find flight deals from St. Louis to Panama City Beach

Keep the following information in mind while searching for St. Louis to Panama City Beach flight deals. Data was last updated December 24, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$289
(Delta)

One-way from

$145
(Delta)

Popular in

March

Cheapest in

October

Average price

$302
Provider with most accurate pricing for Lambert-St Louis-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Panama City NW Florida Beaches flights.
Search Deals
From Lambert-St Louis to Panama City Beach
Search Deals
One-way flight from Lambert-St Louis to Panama City Beach
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($63 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Panama City Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 24, 2025.
Use the filters below to find and compare flights from St. Louis to Panama City Beach that are best for you.

Fly from

St. Louis

Fly to

Panama City Beach

Route

Depart

Return

Price

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Sat 5/23

7:20 am-1:55 pm

1 stop6h 35m

Panama City NW Florida Beaches

Sat 5/30

7:45 am-12:54 pm

1 stop5h 09m

$289

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Tue 1/27

1:00 pm-6:14 pm

1 stop5h 14m

Panama City NW Florida Beaches

Thu 1/29

6:09 pm-11:37 pm

1 stop5h 28m

$289

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Sat 4/25

1:11 pm-7:38 pm

1 stop6h 27m

Panama City NW Florida Beaches

Mon 4/27

7:15 am-12:06 pm

1 stop4h 51m

$289

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Sun 5/31

7:20 am-12:38 pm

1 stop5h 18m

Panama City NW Florida Beaches

Sun 6/7

1:30 pm-6:02 pm

1 stop4h 32m

$289

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Wed 4/29

11:43 am-3:19 pm

1 stop3h 36m

Panama City NW Florida Beaches

Sat 5/2

7:15 am-12:06 pm

1 stop4h 51m

$289

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Fri 3/6

4:55 pm-8:35 pm

1 stop3h 40m

Panama City NW Florida Beaches

Mon 3/9

6:00 pm-12:05 am

1 stop6h 05m

$314

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Tue 3/31

12:04 pm-5:58 pm

1 stop5h 54m

Panama City NW Florida Beaches

Sun 4/5

6:43 pm-11:58 pm

1 stop5h 15m

$314

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Thu 4/9

6:59 pm-11:04 pm

1 stop4h 05m

Panama City NW Florida Beaches

Mon 4/13

7:15 am-12:06 pm

1 stop4h 51m

$314

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Thu 3/26

6:59 pm-11:04 pm

1 stop4h 05m

Panama City NW Florida Beaches

Sun 3/29

7:05 am-11:09 am

1 stop4h 04m

$314

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Wed 4/29

11:43 am-3:19 pm

1 stop3h 36m

Panama City NW Florida Beaches

Sun 5/3

7:15 am-12:06 pm

1 stop4h 51m

$314

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Showing 1-10 of 21 results
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2
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Best time to book a flight from St. Louis to Panama City Beach

Have a flexible travel schedule? Discover the best time to fly to Panama City Beach from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Panama City Beach

How far ahead should I book a flight from St. Louis to Panama City Beach?

Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Panama City Beach. Price data was last updated on December 19, 2025.

The best time to book flights from St. Louis to Panama City Beach is 88 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from St. Louis to Panama City Beach?

Currently, July is the cheapest month in which you can book a flight from St. Louis to Panama City Beach (average of $82). Flying from St. Louis to Panama City Beach in January is currently the most expensive (average of $216). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to PA9?

Find hourly flight availability from St. Louis to Panama City Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 24, 2025.

It’s optimal to fly from St. Louis to Panama City Beach in the evening. By choosing this option you can save up to 29% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from St. Louis to Panama City Beach?

Use this chart to determine the cheapest time to fly round-trip from St. Louis to Panama City Beach. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their St. Louis to Panama City Beach flight should consider departing on Monday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from St. Louis to Panama City Beach?

Reviews of airlines servicing Panama City Beach

Get insights into the airlines that provide service to Panama City Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City Beach. Reviews last updated December 24, 2025.
Read through reviews of airlines operating flights from St. Louis to Panama City Beach, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,255 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,255 reviews
Southwest
8.0
Very good
4,255 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,013 reviews
Southwest
8.0
Very good
4,255 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,054 reviews
Southwest
8.0
Very good
4,255 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Panama City Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Panama City Beach?

    Most people fly from Lambert-St Louis (STL) if they book a flight from St. Louis to Panama City Beach. On average, Lambert-St Louis has 0 outbound flights to Panama City Beach per day from 4 airlines. Lambert-St Louis is conveniently located just 12.7 mi from St. Louis’s city center.

  • How popular is this St. Louis to Panama City Beach flight route?

    Flights from Lambert-St Louis to Panama City Beach have been viewed 3 times in the past calendar month.

  • How long is the flight from St. Louis to Panama City Beach?

    Delta can get you from St. Louis to Panama City Beach in just under 6h 35m. Your travel time can differ by up to . The distance from St. Louis to Panama City Beach is about 635 mi.

  • What are the cheapest airlines to fly from St. Louis to Panama City Beach one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $88. However, be on the lookout for offers from American Airlines and Southwest, as they are both options that can get you from St. Louis to Panama City Beach for a low price.

  • Can I find deals for flights from St. Louis to Panama City Beach that include hotel bookings?

    Yes. In addition to deals on St. Louis to Panama City Beach flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Panama City Beach?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Panama City Beach.

  • Can I find deals for business class flights from St. Louis to Panama City Beach?

    Yes. Cheapflights offers flight deals from St. Louis to Panama City Beach by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Panama City Beach?

    Currently, July is the cheapest month in which you can book a flight from St. Louis to Panama City Beach (average of $82). Flying from St. Louis to Panama City Beach in January is currently the most expensive (average of $216). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from St. Louis to Panama City Beach

Discover the top 4 airlines that operate flights from St. Louis to Panama City Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$82Average$151FlexibilityNo cancel feeOn-time88%
DeltaCheapest$165Average$353FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$185Average$394FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$228Average$413FlexibilityNo cancel feeOn-time63%

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