$59+ Cheap flights from Missouri to Ohio
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/1. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CLE
Jun 9 — Jun 161
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Missouri to Ohio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Ohio
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missouri to OhioExplore the most affordable flight options available from Missouri to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 10, 2026.
Explore the most affordable flight options available from Missouri to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 10, 2026.
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:15 pm
STL
- CLE
Nonstop1h 30m
Southwest
Tue 6/237:55 pm
CLE
- STL
Nonstop1h 35m
Southwest
Deal found 5/8![Southwest logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/104:52 pm
STL
- DTW
1 stop6h 48m
Frontier
Tue 7/142:02 pm
DTW
- STL
1 stop19h 55m
Frontier
Deal found 5/6![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:24 pm
MCI
- CVG
1 stop16h 17m
Frontier
Fri 6/1212:54 pm
CVG
- MCI
1 stop5h 27m
Frontier
Deal found 5/8![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:16 pm
MCI
- CLE
1 stop16h 33m
Frontier
Thu 8/63:46 pm
CLE
- MCI
1 stop26h 35m
Frontier
Deal found 5/9![Frontier logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/224:52 pm
STL
- DTW
1 stop6h 48m
Frontier
Sat 7/252:54 pm
DTW
- STL
1 stop27h 43m
Frontier
Deal found 5/5![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:16 pm
MCI
- CVG
1 stop16h 32m
Frontier
Mon 8/312:54 pm
CVG
- MCI
1 stop5h 27m
Frontier
Deal found 5/6![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:33 pm
STL
- CLE
1 stop16h 17m
Frontier
Sun 6/78:46 pm
CLE
- STL
1 stop13h 09m
Frontier
Deal found 5/9![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:24 pm
MCI
- CLE
1 stop13h 29m
Frontier
Wed 6/106:37 am
CLE
- MCI
1 stop11h 44m
Frontier
Deal found 5/7![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:33 pm
STL
- CLE
1 stop16h 16m
Frontier
Wed 8/127:24 pm
CLE
- STL
1 stop23h 13m
Frontier
Deal found 5/6![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:33 pm
STL
- CLE
1 stop18h 58m
Frontier
Tue 6/93:46 pm
CLE
- STL
1 stop18h 01m
Frontier
Deal found 5/5![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:24 pm
MCI
- CVG
1 stop15h 40m
Frontier
Wed 6/1012:54 pm
CVG
- MCI
1 stop5h 27m
Frontier
Deal found 5/6![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:24 pm
MCI
- CLE
1 stop13h 29m
Frontier
Wed 6/106:37 am
CLE
- MCI
1 stop11h 44m
Frontier
Deal found 5/6![Frontier logo]()
$129
Best flights from Missouri to OhioDiscover carefully curated flight deals from Missouri to Ohio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 10, 2026.
Discover carefully curated flight deals from Missouri to Ohio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 10, 2026.
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:15 pm
STL
- CLE
Nonstop1h 30m
Southwest
Tue 6/237:55 pm
CLE
- STL
Nonstop1h 35m
Southwest
Deal found 5/8![Southwest logo]()
$117
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:13 am
STL
- CLE
1 stop6h 18m
Delta
Wed 8/268:08 am
CLE
- STL
1 stop6h 06m
Delta
Deal found 5/5![Delta logo]()
$179
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/911:25 am
STL
- PIT
1 stop4h 45m
United Airlines
Wed 6/106:16 pm
PIT
- STL
1 stop4h 05m
United Airlines
Deal found 5/5![United Airlines logo]()
$264
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:30 am
STL
- CLE
Nonstop1h 30m
Southwest
Tue 6/97:55 pm
CLE
- STL
Nonstop1h 35m
Southwest
Deal found 5/7![Southwest logo]()
$137
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:26 am
MCI
- CVG
1 stop5h 30m
American Airlines
Tue 8/186:25 pm
CVG
- MCI
1 stop6h 00m
American Airlines
Deal found 5/7![American Airlines logo]()
$347
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:40 am
STL
- CLE
Nonstop1h 30m
Southwest
Wed 8/266:25 pm
CLE
- STL
1 stop4h 45m
Southwest
Deal found 5/5![Southwest logo]()
$174
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2810:19 am
STL
- DTW
Nonstop1h 34m
Delta
Tue 8/412:36 pm
DTW
- STL
Nonstop1h 38m
Delta
Deal found 5/6![Delta logo]()
$209
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1010:15 am
STL
- CLE
2 stops7h 20m
Southwest
Wed 6/177:10 pm
CLE
- STL
1 stop4h 15m
Southwest
Deal found 5/8![Southwest logo]()
$189
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/21:59 pm
STL
- DTW
Nonstop1h 34m
Delta
Tue 6/912:30 pm
DTW
- STL
Nonstop1h 39m
Delta
Deal found 5/5![Delta logo]()
$209
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/610:20 am
STL
- CLE
Nonstop1h 30m
Southwest
Mon 6/86:25 am
CLE
- STL
Nonstop1h 35m
Southwest
Deal found 5/6![Southwest logo]()
$191
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:59 pm
STL
- DTW
Nonstop1h 34m
Delta
Mon 6/18:30 pm
DTW
- STL
Nonstop1h 39m
Delta
Deal found 5/6![Delta logo]()
$213
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:29 pm
STL
- CMH
1 stop5h 30m
United Airlines
Sat 6/69:00 am
CMH
- STL
1 stop4h 11m
United Airlines
Deal found 5/6![United Airlines logo]()
$278
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:00 am
STL
- DTW
2 stops7h 34m
United Airlines
Wed 6/1011:00 am
DTW
- STL
1 stop5h 46m
United Airlines
Deal found 5/9![United Airlines logo]()
$286
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:15 pm
STL
- CLE
Nonstop1h 30m
Southwest
Thu 6/254:45 pm
CLE
- STL
1 stop3h 25m
Southwest
Deal found 5/5![Southwest logo]()
$218
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:00 pm
STL
- DTW
1 stop6h 30m
Southwest
Thu 6/48:15 pm
DTW
- STL
Nonstop1h 35m
Southwest
Deal found 5/7![Southwest logo]()
$223
This American Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:12 pm
SGF
- DTW
1 stop5h 29m
American Airlines
Tue 7/219:13 pm
DTW
- SGF
1 stop13h 50m
American Airlines
Deal found 5/9![American Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:55 am
STL
- CLE
1 stop4h 05m
Southwest
Fri 7/35:45 pm
CLE
- STL
2 stops6h 00m
Southwest
Deal found 5/10![Southwest logo]()
$223
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:01 pm
STL
- CMH
1 stop4h 29m
Delta
Fri 6/57:00 pm
CMH
- STL
1 stop5h 59m
Delta
Deal found 5/5![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:30 am
SGF
- DTW
1 stop4h 55m
United Airlines
Sat 8/224:26 pm
DTW
- SGF
2 stops8h 16m
United Airlines
Deal found 5/10![United Airlines logo]()
$336
This KAYAK deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:16 pm
MCI
- CMH
1 stop5h 36m
American Airlines
Wed 6/32:52 pm
CMH
- MCI
1 stop8h 08m
American Airlines
Deal found 5/7![American Airlines logo]()
$388
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:30 am
STL
- CMH
1 stop3h 57m
Delta
Sun 6/216:30 am
CMH
- STL
1 stop4h 02m
Delta
Deal found 5/5![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:35 pm
SGF
- DTW
1 stop4h 22m
United Airlines
Mon 5/257:05 am
DTW
- SGF
1 stop4h 37m
United Airlines
Deal found 5/6![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:40 pm
STL
- DTW
1 stop3h 30m
Southwest
Mon 6/13:35 pm
DTW
- STL
2 stops8h 40m
Southwest
Deal found 5/6![Southwest logo]()
$238
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:10 pm
STL
- PIT
1 stop4h 57m
Delta
Sun 6/216:30 am
PIT
- STL
1 stop4h 02m
Delta
Deal found 5/9![Delta logo]()
$303
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:12 pm
SGF
- DTW
1 stop5h 21m
American Airlines
Mon 6/226:45 am
DTW
- SGF
1 stop4h 19m
American Airlines
Deal found 5/10![American Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:10 pm
MCI
- CLE
1 stop4h 19m
United Airlines
Tue 7/77:08 pm
CLE
- MCI
1 stop5h 51m
United Airlines
Deal found 5/10![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/163:15 pm
STL
- DTW
2 stops6h 35m
Southwest
Wed 6/175:35 am
DTW
- STL
2 stops6h 40m
Southwest
Deal found 5/5![Southwest logo]()
$239
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:41 pm
MCI
- CVG
1 stop4h 18m
United Airlines
Wed 6/38:00 pm
CVG
- MCI
1 stop4h 13m
United Airlines
Deal found 5/5![United Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:46 pm
MCI
- CVG
1 stop4h 16m
Delta
Tue 8/186:05 am
CVG
- MCI
1 stop4h 40m
Delta
Deal found 5/10![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/98:30 am
STL
- PIT
1 stop8h 15m
Southwest
Wed 6/106:45 am
PIT
- STL
Nonstop1h 45m
Southwest
Deal found 5/5![Southwest logo]()
$266
Last-minute flights from Missouri to OhioDiscover last-minute flight deals from Missouri to Ohio. Data last updated May 10, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Ohio. Data last updated May 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:33 pm
STL
- CLE
1 stop18h 58m
Frontier
Tue 6/93:46 pm
CLE
- STL
1 stop18h 01m
Frontier
Deal found 5/5![Frontier logo]()
$126
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:30 am
STL
- CLE
Nonstop1h 30m
Southwest
Tue 6/97:55 pm
CLE
- STL
Nonstop1h 35m
Southwest
Deal found 5/7![Southwest logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:33 pm
STL
- DTW
1 stop5h 06m
Frontier
Tue 6/96:54 pm
DTW
- STL
1 stop14h 53m
Frontier
Deal found 5/5![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:24 pm
MCI
- CVG
1 stop15h 40m
Frontier
Wed 6/1012:54 pm
CVG
- MCI
1 stop5h 27m
Frontier
Deal found 5/6![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:24 pm
MCI
- CLE
1 stop13h 29m
Frontier
Wed 6/106:37 am
CLE
- MCI
1 stop11h 44m
Frontier
Deal found 5/6![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:33 pm
STL
- CLE
1 stop16h 17m
Frontier
Sun 6/78:46 pm
CLE
- STL
1 stop13h 09m
Frontier
Deal found 5/9![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:24 pm
MCI
- CVG
1 stop16h 17m
Frontier
Fri 6/1212:54 pm
CVG
- MCI
1 stop5h 27m
Frontier
Deal found 5/8![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:24 pm
MCI
- CLE
1 stop13h 29m
Frontier
Wed 6/106:37 am
CLE
- MCI
1 stop11h 44m
Frontier
Deal found 5/7![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:33 pm
STL
- CLE
1 stop16h 17m
Frontier
Thu 6/116:37 am
CLE
- STL
1 stop11h 53m
Frontier
Deal found 5/7![Frontier logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/146:31 pm
STL
- CLE
1 stop16h 21m
Frontier
Tue 6/165:51 pm
CLE
- STL
1 stop16h 01m
Frontier
Deal found 5/7![Frontier logo]()
$140
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:15 pm
STL
- CLE
Nonstop1h 30m
Southwest
Tue 6/237:55 pm
CLE
- STL
Nonstop1h 35m
Southwest
Deal found 5/8![Southwest logo]()
$117
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2310:15 am
STL
- CLE
2 stops7h 20m
Southwest
Tue 6/237:55 pm
CLE
- STL
Nonstop1h 35m
Southwest
Deal found 5/6![Southwest logo]()
$152
One-way flights from Missouri to OhioSearch for one-way flight options from Missouri to Ohio. Find affordable one-way fares based on user searches. Data last updated May 10, 2026.
Search for one-way flight options from Missouri to Ohio. Find affordable one-way fares based on user searches. Data last updated May 10, 2026.
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:15 pm
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 5/8![Southwest logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:33 pm
STL
- DTW
1 stop21h 17m
Frontier
Deal found 5/6![Frontier logo]()
$62
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:16 pm
MCI
- DTW
1 stop18h 28m
Frontier
Deal found 5/8![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:06 pm
STL
- DTW
1 stop6h 38m
Frontier
Deal found 5/9![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:33 pm
STL
- CLE
1 stop16h 17m
Frontier
Deal found 5/9![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:24 pm
MCI
- CLE
1 stop13h 29m
Frontier
Deal found 5/5![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:16 pm
MCI
- DTW
1 stop18h 28m
Frontier
Deal found 5/5![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:33 pm
STL
- DTW
1 stop29h 07m
Frontier
Deal found 5/5![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:16 pm
MCI
- CMH
1 stop21h 48m
Frontier
Deal found 5/10![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:33 pm
STL
- CLE
1 stop16h 59m
Frontier
Deal found 5/5![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:27 pm
STL
- CMH
1 stop22h 43m
Frontier
Deal found 5/6![Frontier logo]()
$65
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:30 am
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 5/5![Southwest logo]()
$69
Find flight deals from Missouri to Ohio
Keep the following information in mind while searching for Missouri to Ohio flight deals. Data was last updated May 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $117 (Southwest) |
One-way from | $59 (Southwest) |
Popular in | January |
Cheapest in | September |
Average price | $298 |
Good round-trip deal | $177 or less |
Good one-way deal | $185 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 10, 2026.
Use the filters below to find and compare flights from Missouri to Ohio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
St. LouisCleveland
STL - CLE
STLCLE
Lambert-St Louis
Tue 6/16
7:15 pm-9:45 pm
Nonstop1h 30m
Cleveland Hopkins Intl
Tue 6/23
7:55 pm-8:30 pm
Nonstop1h 35m
$117
St. LouisCleveland
STL - CLE
STLCLE
Lambert-St Louis
Tue 6/2
11:30 am-2:00 pm
Nonstop1h 30m
Cleveland Hopkins Intl
Tue 6/9
7:55 pm-8:30 pm
Nonstop1h 35m
$137
St. LouisCleveland
STL - CLE
STLCLE
Lambert-St Louis
Mon 8/24
10:40 am-1:10 pm
Nonstop1h 30m
Cleveland Hopkins Intl
Wed 8/26
6:25 pm-10:10 pm
1 stop4h 45m
$174
St. LouisCleveland
STL - CLE
STLCLE
Lambert-St Louis
Mon 8/24
11:13 am-6:31 pm
1 stop6h 18m
Cleveland Hopkins Intl
Wed 8/26
8:08 am-1:14 pm
1 stop6h 06m
$179
St. LouisCleveland
STL - CLE
STLCLE
Lambert-St Louis
Wed 6/10
10:15 am-6:35 pm
2 stops7h 20m
Cleveland Hopkins Intl
Wed 6/17
7:10 pm-10:25 pm
1 stop4h 15m
$189
St. LouisCleveland
STL - CLE
STLCLE
Lambert-St Louis
Sat 6/6
10:20 am-12:50 pm
Nonstop1h 30m
Cleveland Hopkins Intl
Mon 6/8
6:25 am-7:00 am
Nonstop1h 35m
$191
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Tue 7/28
10:19 am-12:53 pm
Nonstop1h 34m
Detroit Metropolitan Wayne County
Tue 8/4
12:36 pm-1:14 pm
Nonstop1h 38m
$209
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Tue 6/2
1:59 pm-4:33 pm
Nonstop1h 34m
Detroit Metropolitan Wayne County
Tue 6/9
12:30 pm-1:09 pm
Nonstop1h 39m
$209
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Thu 5/28
1:59 pm-4:33 pm
Nonstop1h 34m
Detroit Metropolitan Wayne County
Mon 6/1
8:30 pm-9:09 pm
Nonstop1h 39m
$213
St. LouisCleveland
STL - CLE
STLCLE
Lambert-St Louis
Tue 6/23
7:15 pm-9:45 pm
Nonstop1h 30m
Cleveland Hopkins Intl
Thu 6/25
4:45 pm-7:10 pm
1 stop3h 25m
$218
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Ohio
Have a flexible travel schedule? Discover the best time to fly to Ohio from Missouri with our price prediction graph.
STL-CLE
MCI-CVG
MCI-CLE
STL-DTW
STL-PIT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Ohio
USMO-USOH
STL-CLE
MCI-CVG
MCI-CLE
STL-DTW
How far ahead should I book a flight from Missouri to Ohio?
The price you pay for your flight from Missouri to Ohio may vary depending on when you book. For the best chance of a lower fare, look to book 56 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Missouri to Ohio?
Currently, September is the cheapest month in which you can book a flight from Missouri to Ohio (average of $89). Flying from Missouri to Ohio in April is currently the most expensive (average of $207). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to OH?
Find hourly flight availability from Missouri to Ohio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 10, 2026.
One of the essential ways to save on airfare from Missouri to Ohio is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 27% on airfare.
How much does it cost to fly round-trip from Missouri to Ohio?
Reviews of airlines servicing Ohio
Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated May 10, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Missouri to Ohio by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
7.9
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
7.9
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
7.9
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
7.9
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
7.9
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Missouri to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for Missouri to Ohio
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Ohio by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Ohio by cabin class
Find flights from Missouri to Ohio, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Ohio flights
Browse other Missouri and Ohio flight options. Last updated on May 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Ohio
Find the right flight back to Missouri after your stay in Ohio
Missouri to Ohio flights
Consider these flights traveling from Missouri to Ohio.
Top 6 airlines flying from Missouri to Ohio
Discover the top 6 airlines that operate flights from Missouri to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$144 | Average$241 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$168 | Average$379 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$168 | Average$378 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$186 | Average$395 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$196 | Average$409 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$203 | Average$328 | FlexibilityNo cancel fee | On-time65% |