$49+ Cheap flights from Missouri to Ohio
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CVG
Apr 12 — Apr 191
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to OhioExplore the most affordable flight options available from Missouri to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
Explore the most affordable flight options available from Missouri to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:30 am
STL
- CLE
Nonstop1h 30m
Southwest
Tue 4/147:05 am
CLE
- STL
Nonstop1h 40m
Southwest
Deal found 3/10![Southwest logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:41 pm
STL
- DTW
1 stop5h 18m
Frontier
Tue 5/121:31 pm
DTW
- STL
1 stop20h 24m
Frontier
Deal found 3/12![Frontier logo]()
$134
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:10 pm
STL
- CLE
Nonstop1h 30m
Southwest
Wed 4/157:05 am
CLE
- STL
Nonstop1h 40m
Southwest
Deal found 3/9![Southwest logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:27 pm
STL
- CMH
1 stop22h 43m
Frontier
Sun 5/106:05 pm
CMH
- STL
1 stop15h 50m
Frontier
Deal found 3/12![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Fri 5/18:49 pm
DTW
- STL
1 stop11h 01m
Frontier
Deal found 3/11![Frontier logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:55 pm
STL
- CLE
1 stop25h 02m
Frontier
Tue 5/126:54 am
CLE
- STL
1 stop27h 01m
Frontier
Deal found 3/11![Frontier logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:25 am
STL
- CVG
1 stop5h 08m
Frontier
Sun 4/266:53 pm
CVG
- STL
1 stop12h 57m
Frontier
Deal found 3/12![Frontier logo]()
$159
This Expedia deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:06 pm
STL
- DTW
1 stop13h 52m
Frontier
Sun 4/2610:27 pm
DTW
- STL
1 stop22h 05m
Frontier
Deal found 3/9![Frontier logo]()
$160
This Expedia deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2412:14 pm
STL
- CLE
1 stop17h 52m
Frontier
Wed 3/2510:00 pm
CLE
- STL
1 stop26h 19m
Frontier
Deal found 3/8![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:23 pm
STL
- DTW
1 stop14h 22m
Frontier
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Deal found 3/12![Frontier logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:17 pm
STL
- DTW
1 stop13h 41m
Frontier
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Deal found 3/11![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:29 pm
STL
- DTW
1 stop12h 33m
Frontier
Tue 4/147:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Deal found 3/8![Frontier logo]()
$174
Best flights from Missouri to OhioDiscover carefully curated flight deals from Missouri to Ohio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
Discover carefully curated flight deals from Missouri to Ohio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:30 am
STL
- CLE
Nonstop1h 30m
Southwest
Tue 4/146:15 am
CLE
- STL
1 stop6h 10m
Southwest
Deal found 3/10![Southwest logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:23 pm
STL
- CVG
1 stop20h 25m
Frontier
Sat 5/24:26 pm
CVG
- STL
1 stop7h 53m
Frontier
Deal found 3/11![Frontier logo]()
$248
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:15 am
STL
- CMH
1 stop5h 34m
Delta
Tue 5/126:44 pm
CMH
- STL
1 stop6h 15m
Delta
Deal found 3/8![Delta logo]()
$255
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:30 am
STL
- CLE
Nonstop1h 30m
Southwest
Tue 5/127:40 pm
CLE
- STL
Nonstop1h 40m
Southwest
Deal found 3/11![Southwest logo]()
$134
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:00 am
MCI
- CVG
1 stop4h 10m
United Airlines
Wed 4/157:00 am
CVG
- MCI
1 stop6h 24m
United Airlines
Deal found 3/11![United Airlines logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2411:19 am
MCI
- CVG
2 stops25h 25m
Multiple Airlines
Mon 4/276:00 am
CVG
- MCI
1 stop12h 06m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$292
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:00 am
MCI
- CVG
1 stop5h 47m
American Airlines
Thu 4/167:56 am
CVG
- MCI
1 stop7h 52m
American Airlines
Deal found 3/9![American Airlines logo]()
$301
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:00 pm
STL
- CLE
1 stop6h 20m
Southwest
Sat 4/255:40 am
CLE
- STL
2 stops8h 55m
Southwest
Deal found 3/8![Southwest logo]()
$212
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Mon 6/88:15 pm
DTW
- STL
Nonstop1h 35m
Southwest
Deal found 3/8![Southwest logo]()
$215
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:59 pm
STL
- CMH
1 stop4h 25m
Delta
Sun 4/126:15 am
CMH
- STL
1 stop4h 31m
Delta
Deal found 3/8![Delta logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:19 am
MCI
- CVG
1 stop6h 17m
Frontier
Sun 4/196:53 pm
CVG
- MCI
1 stop16h 35m
Frontier
Deal found 3/12![Frontier logo]()
$270
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:25 am
STL
- CLE
1 stop5h 48m
United Airlines
Wed 4/16:00 am
CLE
- STL
1 stop5h 28m
United Airlines
Deal found 3/12![United Airlines logo]()
$281
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Mon 4/208:15 pm
DTW
- STL
Nonstop1h 40m
Southwest
Deal found 3/10![Southwest logo]()
$215
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:30 pm
STL
- CLE
1 stop6h 07m
Delta
Sun 6/217:00 am
CLE
- STL
1 stop6h 54m
Delta
Deal found 3/10![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:15 am
MCI
- PIT
2 stops6h 39m
United Airlines
Wed 4/222:09 pm
PIT
- MCI
1 stop4h 29m
United Airlines
Deal found 3/9![United Airlines logo]()
$292
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:10 pm
STL
- CLE
Nonstop1h 30m
Southwest
Sun 5/315:30 am
CLE
- STL
1 stop6h 35m
Southwest
Deal found 3/9![Southwest logo]()
$224
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:50 pm
STL
- PIT
1 stop4h 50m
Delta
Mon 4/277:46 pm
PIT
- STL
1 stop4h 50m
Delta
Deal found 3/9![Delta logo]()
$284
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/154:51 pm
MCI
- CLE
1 stop5h 45m
American Airlines
Mon 5/188:45 pm
CLE
- MCI
1 stop4h 31m
American Airlines
Deal found 3/10![American Airlines logo]()
$347
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/122:30 pm
STL
- CLE
2 stops6h 45m
Southwest
Thu 5/213:45 pm
CLE
- STL
2 stops8h 30m
Southwest
Deal found 3/10![Southwest logo]()
$226
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2811:25 am
STL
- CMH
1 stop4h 21m
United Airlines
Mon 3/305:59 pm
CMH
- STL
1 stop4h 09m
United Airlines
Deal found 3/10![United Airlines logo]()
$305
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:30 pm
STL
- PIT
1 stop5h 54m
Delta
Mon 7/67:55 pm
PIT
- STL
1 stop4h 43m
Delta
Deal found 3/8![Delta logo]()
$287
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/274:25 pm
STL
- CLE
2 stops6h 30m
Southwest
Mon 3/308:05 pm
CLE
- STL
Nonstop1h 45m
Southwest
Deal found 3/9![Southwest logo]()
$230
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:45 am
STL
- DTW
1 stop4h 35m
United Airlines
Sun 4/57:18 am
DTW
- STL
1 stop6h 04m
United Airlines
Deal found 3/12![United Airlines logo]()
$307
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:15 am
MCI
- CLE
2 stops6h 55m
United Airlines
Wed 4/84:14 pm
CLE
- MCI
1 stop4h 31m
United Airlines
Deal found 3/10![United Airlines logo]()
$308
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/282:30 pm
STL
- DTW
2 stops7h 00m
Southwest
Fri 5/17:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Deal found 3/12![Southwest logo]()
$234
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:40 am
STL
- DTW
1 stop3h 30m
Southwest
Fri 4/107:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Deal found 3/11![Southwest logo]()
$238
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:25 am
MCI
- PIT
1 stop6h 03m
Delta
Mon 4/67:35 pm
PIT
- MCI
1 stop5h 37m
Delta
Deal found 3/12![Delta logo]()
$357
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:15 am
MCI
- CLE
1 stop6h 04m
United Airlines
Mon 4/274:14 pm
CLE
- MCI
1 stop6h 45m
United Airlines
Deal found 3/12![United Airlines logo]()
$327
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:45 am
STL
- PIT
1 stop6h 40m
Southwest
Mon 4/208:05 pm
PIT
- STL
Nonstop1h 50m
Southwest
Deal found 3/8![Southwest logo]()
$241
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:05 pm
MCI
- CMH
1 stop4h 56m
United Airlines
Thu 4/165:30 am
CMH
- MCI
1 stop4h 22m
United Airlines
Deal found 3/11![United Airlines logo]()
$335
Last-minute flights from Missouri to OhioDiscover last-minute flight deals from Missouri to Ohio. Data last updated March 13, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Ohio. Data last updated March 13, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2412:14 pm
STL
- CLE
1 stop17h 52m
Frontier
Wed 3/2510:00 pm
CLE
- STL
1 stop26h 19m
Frontier
Deal found 3/8![Frontier logo]()
$160
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:30 am
STL
- CLE
Nonstop1h 30m
Southwest
Tue 4/147:05 am
CLE
- STL
Nonstop1h 40m
Southwest
Deal found 3/10![Southwest logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:29 pm
STL
- DTW
1 stop12h 33m
Frontier
Tue 4/147:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Deal found 3/8![Frontier logo]()
$174
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:10 pm
STL
- CLE
Nonstop1h 30m
Southwest
Wed 4/157:05 am
CLE
- STL
Nonstop1h 40m
Southwest
Deal found 3/9![Southwest logo]()
$134
This Expedia deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Thu 4/168:43 pm
DTW
- STL
1 stop11h 07m
Frontier
Deal found 3/12![Frontier logo]()
$180
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:30 am
STL
- CLE
Nonstop1h 30m
Southwest
Mon 4/207:00 am
CLE
- STL
Nonstop1h 40m
Southwest
Deal found 3/11![Southwest logo]()
$171
This Expedia deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Sun 4/1910:27 pm
DTW
- STL
1 stop22h 05m
Frontier
Deal found 3/8![Frontier logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:25 am
STL
- CVG
1 stop5h 08m
Frontier
Sun 4/266:53 pm
CVG
- STL
1 stop12h 57m
Frontier
Deal found 3/12![Frontier logo]()
$159
This Expedia deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:06 pm
STL
- DTW
1 stop13h 52m
Frontier
Sun 4/2610:27 pm
DTW
- STL
1 stop22h 05m
Frontier
Deal found 3/9![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:23 pm
STL
- DTW
1 stop14h 22m
Frontier
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Deal found 3/12![Frontier logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:17 pm
STL
- DTW
1 stop13h 41m
Frontier
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Deal found 3/11![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Fri 5/18:49 pm
DTW
- STL
1 stop11h 01m
Frontier
Deal found 3/11![Frontier logo]()
$148
One-way flights from Missouri to OhioSearch for one-way flight options from Missouri to Ohio. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
Search for one-way flight options from Missouri to Ohio. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/111:30 am
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 3/11![Southwest logo]()
$49
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:30 pm
STL
- CLE
2 stops6h 45m
Southwest
Deal found 3/9![Southwest logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Deal found 3/10![Frontier logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:13 pm
STL
- DTW
1 stop11h 57m
Frontier
Deal found 3/9![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:27 pm
STL
- CLE
1 stop14h 26m
Frontier
Deal found 3/11![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:13 pm
STL
- CMH
1 stop17h 28m
Frontier
Deal found 3/10![Frontier logo]()
$70
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:59 pm
STL
- CLE
1 stop4h 51m
Delta
Deal found 3/10![Delta logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:21 am
STL
- DTW
1 stop19h 41m
Frontier
Deal found 3/9![Frontier logo]()
$78
This Priceline deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:53 am
MCI
- DTW
1 stop5h 53m
Frontier
Deal found 3/8![Frontier logo]()
$80
This Frontier deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:13 am
MCI
- CVG
1 stop6h 23m
Frontier
Deal found 3/9![Frontier logo]()
$80
This Frontier deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/94:55 pm
STL
- CLE
1 stop7h 15m
Frontier
Deal found 3/9![Frontier logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:23 pm
STL
- DTW
1 stop14h 15m
Frontier
Deal found 3/9![Frontier logo]()
$83
Find flight deals from Missouri to Ohio
Keep the following information in mind while searching for Missouri to Ohio flight deals. Data was last updated March 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $97 (Southwest) |
One-way from | $49 (Southwest) |
Popular in | March |
Cheapest in | September |
Average price | $440 |
Good round-trip deal | $235 or less |
Good one-way deal | $164 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Missouri to Ohio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCleveland
STL - CLE
STLCLE
Lambert-St Louis
Tue 4/7
11:30 am-2:00 pm
Nonstop1h 30m
Cleveland Hopkins Intl
Tue 4/14
6:15 am-11:25 am
1 stop6h 10m
$107
St. LouisCleveland
STL - CLE
STLCLE
Lambert-St Louis
Thu 5/7
10:30 am-1:00 pm
Nonstop1h 30m
Cleveland Hopkins Intl
Tue 5/12
7:40 pm-8:20 pm
Nonstop1h 40m
$134
St. LouisCleveland
STL - CLE
STLCLE
Lambert-St Louis
Fri 4/24
4:00 pm-11:20 pm
1 stop6h 20m
Cleveland Hopkins Intl
Sat 4/25
5:40 am-1:35 pm
2 stops8h 55m
$212
Quickest round-trip
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Mon 6/1
7:40 pm-10:10 pm
Nonstop1h 30m
Detroit Metropolitan Wayne County
Mon 6/8
8:15 pm-8:50 pm
Nonstop1h 35m
$215
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Thu 4/16
7:40 pm-10:10 pm
Nonstop1h 30m
Detroit Metropolitan Wayne County
Mon 4/20
8:15 pm-8:55 pm
Nonstop1h 40m
$215
St. LouisCleveland
STL - CLE
STLCLE
Lambert-St Louis
Thu 5/28
8:10 pm-10:40 pm
Nonstop1h 30m
Cleveland Hopkins Intl
Sun 5/31
5:30 am-11:05 am
1 stop6h 35m
$224
St. LouisCleveland
STL - CLE
STLCLE
Lambert-St Louis
Tue 5/12
2:30 pm-10:15 pm
2 stops6h 45m
Cleveland Hopkins Intl
Thu 5/21
3:45 pm-11:15 pm
2 stops8h 30m
$226
St. LouisCleveland
STL - CLE
STLCLE
Lambert-St Louis
Fri 3/27
4:25 pm-11:55 pm
2 stops6h 30m
Cleveland Hopkins Intl
Mon 3/30
8:05 pm-8:50 pm
Nonstop1h 45m
$230
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Tue 4/28
2:30 pm-10:30 pm
2 stops7h 00m
Detroit Metropolitan Wayne County
Fri 5/1
7:00 am-7:45 am
Nonstop1h 45m
$234
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Thu 4/9
5:40 am-10:10 am
1 stop3h 30m
Detroit Metropolitan Wayne County
Fri 4/10
7:00 am-7:45 am
Nonstop1h 45m
$238
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Ohio
Have a flexible travel schedule? Discover the best time to fly to Ohio from Missouri with our price prediction graph.
STL-CLE
MCI-CVG
STL-DTW
MCI-CLE
STL-CVG
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Ohio
USMO-USOH
STL-CLE
MCI-CVG
STL-DTW
MCI-CLE
What is the cheapest month to book a flight from Missouri to Ohio?
Currently, September is the cheapest month in which you can book a flight from Missouri to Ohio (average of $146). Flying from Missouri to Ohio in January is currently the most expensive (average of $203). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to OH?
Find hourly flight availability from Missouri to Ohio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 13, 2026.
One of the essential ways to save on airfare from Missouri to Ohio is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 26% on airfare.
Weekly flight availability from Missouri to Ohio
Explore weekly flight availability from Missouri to Ohio. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 13, 2026.
The most flights from USMO to USOH are scheduled on a Monday (1 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).
Reviews of airlines servicing Ohio
Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated March 13, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Missouri to Ohio by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Missouri to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missouri to Ohio
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Ohio by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Ohio by cabin class
Find flights from Missouri to Ohio, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Ohio flights
Browse other Missouri and Ohio flight options. Last updated on March 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Ohio
Find the right flight back to Missouri after your stay in Ohio
Missouri to Ohio flights
Consider these flights traveling from Missouri to Ohio.
Top 6 airlines flying from Missouri to Ohio
Discover the top 6 airlines that operate flights from Missouri to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$89 | Average$217 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$168 | Average$365 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$186 | Average$370 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$196 | Average$409 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$203 | Average$328 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$206 | Average$378 | FlexibilityNo cancel fee | On-time63% |