Ohio

$64+ Cheap flights from Missouri to Ohio

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CVG
Jan 14 — Jan 211
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Ohio with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Ohio

Cheapest flights from Missouri to Ohio
Explore the most affordable flight options available from Missouri to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This Orbitz deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2110:57 amSTL - CLE
1 stop11h 16mFrontier
Mon 1/56:59 pmCLE - STL
1 stop28h 34mFrontier
Deal found 12/14$187
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:15 pmMCI - CLE
1 stop15h 22mMultiple Airlines
Wed 1/72:23 pmCLE - MCI
1 stop21h 08mMultiple Airlines
Deal found 12/14$206
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:53 amMCI - CLE
1 stop11h 02mMultiple Airlines
Thu 1/17:45 amCLE - MCI
1 stop10h 25mMultiple Airlines
Deal found 12/14$227
This Expedia deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2010:10 pmSTL - CLE
1 stop31h 00mFrontier
Mon 12/228:48 amCLE - STL
1 stop14h 45mFrontier
Deal found 12/13$234
This Frontier deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1810:42 amSTL - DTW
1 stop6h 27mFrontier
Sun 12/2110:01 pmDTW - STL
1 stop13h 01mFrontier
Deal found 12/13$238
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:35 amMCI - CLE
2 stops10h 41mAmerican Airlines
Thu 1/16:26 pmCLE - MCI
1 stop4h 56mAmerican Airlines
Deal found 12/14$260
This Frontier deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:07 amSTL - CLE
1 stop10h 43mFrontier
Wed 12/244:48 pmCLE - STL
1 stop6h 45mFrontier
Deal found 12/12$264
This Expedia deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/199:07 amSTL - CLE
1 stop10h 08mFrontier
Sun 12/219:30 pmCLE - STL
1 stop11h 42mFrontier
Deal found 12/14$272
This Mytrip deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:15 pmMCI - PIT
1 stop14h 43mSpirit Airlines
Thu 1/18:00 amPIT - MCI
1 stop10h 10mSpirit Airlines
Deal found 12/13$282
This Orbitz deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:45 pmMCI - DTW
1 stop23h 21mFrontier
Sat 1/312:20 pmDTW - MCI
1 stop8h 31mFrontier
Deal found 12/13$283
This Frontier deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/153:30 pmSTL - CLE
1 stop6h 16mFrontier
Tue 12/168:20 pmCLE - STL
1 stop14h 54mFrontier
Deal found 12/13$294
This Expedia deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1811:51 amSTL - DTW
1 stop6h 43mMultiple Airlines
Sun 12/2110:01 pmDTW - STL
1 stop13h 01mMultiple Airlines
Deal found 12/14$310

Find flight deals from Missouri to Ohio

Keep the following information in mind while searching for Missouri to Ohio flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$145
(Travelocity)

One-way from

$64
(Expedia)

Popular in

January

Cheapest in

September

Average price

$466

Good round-trip deal

$272 or less

Good one-way deal

$107 or less
Provider with most accurate pricing for Lambert-St Louis-Cleveland Hopkins Intl flight deals.
Provider most trusted by Cheapflights users for Lambert-St Louis-Cleveland Hopkins Intl flights.
From Missouri to Ohio
One-way flight from Missouri to Ohio
Highest demand for flights based on searches. 31% potential increase in price ($160 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
Average for round-trip flights in December 2025
Price to beat on a round-trip flight from Missouri to Ohio.
Price to beat on a one-way flight from Missouri to Ohio.

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Missouri to Ohio that are best for you.

Fly from

Missouri

Fly to

Ohio

Route

Depart

Return

Price

St. LouisDetroit

STL - DTW

STLDTW

Lambert-St Louis

Mon 1/26

8:22 pm-1:30 pm

1 stop16h 08m

Detroit Metropolitan Wayne County

Sun 2/8

7:14 pm-6:51 am

1 stop12h 37m

$153

St. LouisCleveland

STL - CLE

STLCLE

Lambert-St Louis

Sat 1/10

5:11 pm-7:53 am

1 stop13h 42m

Cleveland Hopkins Intl

Mon 1/12

5:30 am-4:05 pm

1 stop11h 35m

$162

St. LouisCleveland

STL - CLE

STLCLE

Lambert-St Louis

Thu 1/8

3:43 pm-11:13 pm

1 stop6h 30m

Cleveland Hopkins Intl

Mon 1/12

7:24 pm-10:34 pm

1 stop28h 10m

$162

St. LouisDetroit

STL - DTW

STLDTW

Lambert-St Louis

Sun 1/11

5:11 pm-11:41 pm

1 stop29h 30m

Detroit Metropolitan Wayne County

Sun 1/18

5:59 pm-6:51 am

1 stop13h 52m

$171

St. LouisDetroit

STL - DTW

STLDTW

Lambert-St Louis

Fri 1/16

8:32 pm-10:20 am

1 stop12h 48m

Detroit Metropolitan Wayne County

Sun 1/18

5:59 pm-6:51 am

1 stop13h 52m

$172

St. LouisDetroit

STL - DTW

STLDTW

Lambert-St Louis

Fri 2/20

8:17 pm-8:07 am

1 stop10h 50m

Detroit Metropolitan Wayne County

Mon 2/23

10:29 pm-10:27 pm

1 stop24h 58m

$174

St. LouisCleveland

STL - CLE

STLCLE

Lambert-St Louis

Wed 1/21

8:22 pm-7:34 am

1 stop10h 12m

Cleveland Hopkins Intl

Mon 1/26

1:20 pm-6:51 am

2 stops42h 31m

$174

Kansas CityCincinnati

MCI - CVG

MCICVG

Kansas City

Sun 1/11

8:23 pm-1:13 pm

1 stop15h 50m

Cincinnati Cinci./N. Kentucky

Mon 1/12

9:05 pm-4:09 pm

1 stop20h 04m

$176

St. LouisDetroit

STL - DTW

STLDTW

Lambert-St Louis

Thu 1/29

5:42 pm-7:46 pm

1 stop25h 04m

Detroit Metropolitan Wayne County

Mon 2/2

3:14 pm-11:33 pm

1 stop9h 19m

$184

Kansas CityCincinnati

MCI - CVG

MCICVG

Kansas City

Thu 1/8

8:23 pm-1:13 pm

1 stop15h 50m

Cincinnati Cinci./N. Kentucky

Thu 1/15

6:55 am-7:48 pm

1 stop13h 53m

$184

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Missouri to Ohio

Have a flexible travel schedule? Discover the best time to fly to Ohio from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Ohio

What is the cheapest month to book a flight from Missouri to Ohio?

Currently, September is the cheapest month in which you can book a flight from Missouri to Ohio (average of $146). Flying from Missouri to Ohio in March is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to OH?

Find hourly flight availability from Missouri to Ohio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

One of the essential ways to save on airfare from Missouri to Ohio is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 35% on airfare.

What is the cheapest day to fly from Missouri to Ohio?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Ohio. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Ohio flight should consider departing on Saturday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Ohio

Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated December 15, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Missouri to Ohio by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

7.9

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

7.9

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

7.9

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

7.9

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

7.9

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

7.9

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Missouri to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Missouri to Ohio?

    A quick flight from Missouri to Ohio can take about 5h 55m. Frontier provides one of the quickest options available for as low as $191. The distance between Missouri and Ohio is about 552 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Missouri to Ohio that include hotel bookings?

    Yes. In addition to deals on Missouri to Ohio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Ohio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Ohio.

  • Can I find deals for business class flights from Missouri to Ohio?

    Yes. Cheapflights offers flight deals from Missouri to Ohio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Ohio?

    Currently, September is the cheapest month in which you can book a flight from Missouri to Ohio (average of $146). Flying from Missouri to Ohio in March is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Ohio

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Missouri to Ohio

Discover the top 6 airlines that operate flights from Missouri to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$116Average$236FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$168Average$365FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$168Average$361FlexibilityNo cancel feeOn-time71%
DeltaCheapest$196Average$419FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$203Average$272FlexibilityNo cancel feeOn-time65%
SouthwestCheapest$215Average$363FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.