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$55+ Cheap flights from Missouri to Ohio

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CVG
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Missouri to Ohio

Cheapest flights from Missouri to Ohio
Explore the most affordable flight options available from Missouri to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Expedia deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:17 pm
STL
-
CLE
1 stop10h 17m
Frontier
Tue 3/38:46 pm
CLE
-
STL
1 stop11h 05m
Frontier
Deal found 1/27$128
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:17 pm
STL
-
CLE
1 stop10h 17m
Frontier
Fri 2/272:40 pm
CLE
-
STL
1 stop17h 11m
Frontier
Deal found 1/26$133
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2310:55 am
MCI
-
DTW
1 stop25h 35m
Multiple Airlines
Wed 2/258:30 am
DTW
-
MCI
1 stop8h 14m
Multiple Airlines
Deal found 1/26$134
This Expedia deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:33 pm
MCI
-
DTW
1 stop26h 22m
Frontier
Wed 2/258:30 am
DTW
-
MCI
1 stop8h 14m
Frontier
Deal found 1/27$138
This Frontier deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:17 pm
STL
-
DTW
1 stop10h 50m
Frontier
Wed 3/48:30 am
DTW
-
STL
1 stop8h 23m
Frontier
Deal found 1/27$138
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:22 pm
STL
-
DTW
1 stop11h 10m
Frontier
Sun 3/15:06 pm
DTW
-
STL
1 stop14h 45m
Frontier
Deal found 1/25$139
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:17 pm
STL
-
DTW
1 stop10h 50m
Multiple Airlines
Thu 2/262:35 pm
DTW
-
STL
1 stop17h 16m
Multiple Airlines
Deal found 1/27$144
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:17 pm
STL
-
DTW
1 stop10h 50m
Multiple Airlines
Wed 3/410:59 pm
DTW
-
STL
2 stops33h 03m
Multiple Airlines
Deal found 1/27$151
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:00 am
MCI
-
DTW
1 stop9h 05m
Frontier
Sun 3/15:06 pm
DTW
-
MCI
1 stop17h 47m
Frontier
Deal found 1/26$152
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:17 pm
STL
-
DTW
1 stop10h 50m
Multiple Airlines
Sat 2/2110:59 pm
DTW
-
STL
2 stops32h 52m
Multiple Airlines
Deal found 1/26$152
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/273:49 pm
STL
-
CVG
1 stop8h 10m
Frontier
Sun 3/11:07 pm
CVG
-
STL
1 stop18h 44m
Frontier
Deal found 1/27$154
This Priceline deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1410:00 am
MCI
-
CLE
1 stop7h 38m
Frontier
Sat 2/211:20 pm
CLE
-
MCI
1 stop7h 26m
Frontier
Deal found 1/26$154

Find flight deals from Missouri to Ohio

Keep the following information in mind while searching for Missouri to Ohio flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$128
(Expedia)

One-way from

$55
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$388

Good round-trip deal

$249 or less

Good one-way deal

$107 or less
Provider with most accurate pricing for Lambert-St Louis-Cleveland Hopkins Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Cleveland Hopkins Intl flights.
Search Deals
From Missouri to Ohio
Search Deals
One-way flight from Missouri to Ohio
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($46 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Missouri to Ohio.
Search Deals
Price to beat on a one-way flight from Missouri to Ohio.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Missouri to Ohio that are best for you.

Fly from

Missouri

Fly to

Ohio

Route

Depart

Return

Price

St. LouisCleveland

STL - CLE

STLCLE

Lambert-St Louis

Wed 2/25

3:49 pm-12:38 pm

1 stop19h 49m

Cleveland Hopkins Intl

Tue 3/3

8:46 pm-6:51 am

1 stop11h 05m

$128

St. LouisCleveland

STL - CLE

STLCLE

Lambert-St Louis

Wed 2/25

8:17 pm-7:34 am

1 stop10h 17m

Cleveland Hopkins Intl

Fri 2/27

2:40 pm-6:51 am

1 stop17h 11m

$133

St. LouisCincinnati

STL - CVG

STLCVG

Lambert-St Louis

Fri 2/27

3:49 pm-12:59 am

1 stop8h 10m

Cincinnati Cinci./N. Kentucky

Sun 3/1

1:07 pm-6:51 am

1 stop18h 44m

$154

St. LouisCleveland

STL - CLE

STLCLE

Lambert-St Louis

Wed 3/18

6:59 pm-12:29 am

1 stop4h 30m

Cleveland Hopkins Intl

Tue 3/24

6:15 am-9:46 am

1 stop4h 31m

$157

St. LouisCleveland

STL - CLE

STLCLE

Lambert-St Louis

Wed 2/25

8:17 pm-6:09 pm

2 stops20h 52m

Cleveland Hopkins Intl

Tue 3/3

8:46 pm-6:51 am

1 stop11h 05m

$163

St. LouisDetroit

STL - DTW

STLDTW

Lambert-St Louis

Wed 2/18

8:17 pm-8:07 am

1 stop10h 50m

Detroit Metropolitan Wayne County

Sat 2/21

3:17 pm-11:59 pm

1 stop9h 42m

$165

St. LouisDetroit

STL - DTW

STLDTW

Lambert-St Louis

Tue 2/24

3:49 pm-8:57 am

1 stop16h 08m

Detroit Metropolitan Wayne County

Thu 2/26

9:00 am-6:51 am

1 stop22h 51m

$170

St. LouisCleveland

STL - CLE

STLCLE

Lambert-St Louis

Wed 2/18

3:49 pm-11:09 pm

1 stop6h 20m

Cleveland Hopkins Intl

Sat 2/21

6:29 pm-11:59 pm

1 stop6h 30m

$172

Kansas CityCleveland

MCI - CLE

MCICLE

Kansas City

Wed 2/18

4:39 pm-8:55 pm

1 stop27h 16m

Cleveland Hopkins Intl

Sun 2/22

8:48 pm-9:53 am

1 stop14h 05m

$173

St. LouisCleveland

STL - CLE

STLCLE

Lambert-St Louis

Mon 3/9

4:21 pm-10:40 pm

1 stop5h 19m

Cleveland Hopkins Intl

Wed 3/11

4:50 pm-9:06 pm

1 stop5h 16m

$174

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Ohio

Have a flexible travel schedule? Discover the best time to fly to Ohio from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Ohio

What is the cheapest month to book a flight from Missouri to Ohio?

Currently, September is the cheapest month in which you can book a flight from Missouri to Ohio (average of $146). Flying from Missouri to Ohio in March is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to OH?

Find hourly flight availability from Missouri to Ohio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 28, 2026.

One of the essential ways to save on airfare from Missouri to Ohio is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 33% on airfare.

Reviews of airlines servicing Ohio

Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated January 28, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Missouri to Ohio by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Entertainment

7.5

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Entertainment

7.5

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,124 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Entertainment

7.5

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,212 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Entertainment

7.5

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,201 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Entertainment

7.5

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Frontier
5.7
Fair
3,056 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Entertainment

7.5

Crew

8.6

Food

7.0

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Missouri to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Ohio?

    A quick flight from Missouri to Ohio can take about 4h 30m. Frontier provides one of the quickest options available for as low as $157. The distance between Missouri and Ohio is about 486 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Ohio one-way?

    $72 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $84 and $93, respectively.

  • Can I find deals for flights from Missouri to Ohio that include hotel bookings?

    Yes. In addition to deals on Missouri to Ohio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Ohio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Ohio.

  • Can I find deals for business class flights from Missouri to Ohio?

    Yes. Cheapflights offers flight deals from Missouri to Ohio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Ohio?

    Currently, September is the cheapest month in which you can book a flight from Missouri to Ohio (average of $146). Flying from Missouri to Ohio in March is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Ohio

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Missouri to Ohio

Discover the top 6 airlines that operate flights from Missouri to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$89Average$220FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$168Average$363FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$168Average$372FlexibilityNo cancel feeOn-time71%
DeltaCheapest$196Average$414FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$203Average$272FlexibilityNo cancel feeOn-time65%
SouthwestCheapest$215Average$367FlexibilityNo cancel feeOn-time63%

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