$125+ Cheap flights from North Carolina to Panama City, FL (ECP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/1. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — ECP
May 31 — Jun 71
Round-trip
1 adult, Economy
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Find cheap flights from North Carolina to Panama City with Cheapflights
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Cheapest flights from North Carolina to Panama CityExplore the most affordable flight options available from North Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
Explore the most affordable flight options available from North Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:05 am
TYS
- ECP
1 stop3h 25m
Southwest
Tue 6/27:15 am
ECP
- TYS
1 stop3h 45m
Southwest
Deal found 4/26![Southwest logo]()
$249
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:15 am
TYS
- ECP
2 stops11h 40m
Southwest
Wed 6/37:15 am
ECP
- TYS
2 stops8h 55m
Southwest
Deal found 4/29![Southwest logo]()
$259
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:33 pm
TYS
- ECP
1 stop4h 28m
Delta
Mon 5/256:00 am
ECP
- TYS
1 stop4h 09m
Delta
Deal found 4/28![Delta logo]()
$263
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:35 am
TYS
- ECP
1 stop5h 51m
Delta
Thu 6/255:08 pm
ECP
- TYS
1 stop5h 49m
Delta
Deal found 4/29![Delta logo]()
$274
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:33 pm
TYS
- ECP
1 stop4h 55m
Delta
Thu 6/46:45 pm
ECP
- TYS
1 stop4h 11m
Delta
Deal found 4/28![Delta logo]()
$277
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:55 pm
TYS
- ECP
1 stop4h 00m
Southwest
Wed 6/177:40 am
ECP
- TYS
2 stops8h 20m
Southwest
Deal found 4/27![Southwest logo]()
$279
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:05 am
TYS
- ECP
1 stop3h 25m
Southwest
Sat 5/2312:40 pm
ECP
- TYS
1 stop4h 50m
Southwest
Deal found 4/26![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:40 am
TYS
- ECP
1 stop3h 50m
Delta
Thu 6/115:08 pm
ECP
- TYS
1 stop5h 49m
Delta
Deal found 4/28![Delta logo]()
$288
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:00 am
TRI
- ECP
1 stop5h 48m
Delta
Tue 7/149:12 am
ECP
- TRI
1 stop5h 16m
Delta
Deal found 4/28![Delta logo]()
$289
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:35 am
AVL
- ECP
1 stop3h 42m
Delta
Thu 8/69:15 am
ECP
- AVL
1 stop4h 25m
Delta
Deal found 4/30![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:01 am
RDU
- ECP
1 stop6h 27m
American Airlines
Tue 7/76:54 pm
ECP
- RDU
1 stop4h 05m
American Airlines
Deal found 4/30![American Airlines logo]()
$307
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:35 am
GSO
- ECP
1 stop5h 13m
Delta
Sat 7/255:00 pm
ECP
- GSO
1 stop5h 59m
Delta
Deal found 4/30![Delta logo]()
$309
Best flights from North Carolina to Panama CityDiscover carefully curated flight deals from North Carolina to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
Discover carefully curated flight deals from North Carolina to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:59 pm
TYS
- ECP
1 stop6h 02m
Delta
Wed 6/36:00 am
ECP
- TYS
1 stop4h 09m
Delta
Deal found 4/29![Delta logo]()
$249
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:15 am
TYS
- ECP
2 stops11h 40m
Southwest
Wed 6/37:15 am
ECP
- TYS
2 stops8h 55m
Southwest
Deal found 4/29![Southwest logo]()
$259
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:26 pm
TRI
- ECP
1 stop4h 11m
American Airlines
Wed 7/224:17 pm
ECP
- TRI
1 stop4h 40m
American Airlines
Deal found 4/26![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:15 am
ORF
- ECP
2 stops8h 03m
United Airlines
Wed 5/272:26 pm
ECP
- ORF
1 stop7h 04m
United Airlines
Deal found 4/26![United Airlines logo]()
$338
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:35 am
TYS
- ECP
1 stop4h 19m
Delta
Thu 6/257:41 am
ECP
- TYS
1 stop4h 38m
Delta
Deal found 4/26![Delta logo]()
$274
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2512:35 pm
TYS
- ECP
2 stops8h 35m
Southwest
Tue 6/307:40 am
ECP
- TYS
2 stops8h 20m
Southwest
Deal found 4/30![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:00 am
TRI
- ECP
1 stop5h 48m
Delta
Tue 7/149:12 am
ECP
- TRI
1 stop5h 16m
Delta
Deal found 4/28![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:15 am
TYS
- ECP
2 stops11h 40m
Southwest
Sun 6/72:05 pm
ECP
- TYS
1 stop6h 10m
Southwest
Deal found 4/26![Southwest logo]()
$289
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:45 am
ORF
- ECP
2 stops12h 13m
United Airlines
Thu 6/42:05 pm
ECP
- ORF
1 stop6h 32m
United Airlines
Deal found 4/29![United Airlines logo]()
$338
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:35 am
AVL
- ECP
1 stop3h 42m
Delta
Thu 8/69:15 am
ECP
- AVL
1 stop4h 25m
Delta
Deal found 4/30![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:40 am
TYS
- ECP
1 stop3h 55m
Southwest
Tue 7/147:40 am
ECP
- TYS
1 stop3h 25m
Southwest
Deal found 4/29![Southwest logo]()
$299
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/218:41 pm
MYR
- ECP
1 stop3h 59m
American Airlines
Sat 6/276:45 pm
ECP
- MYR
1 stop4h 04m
American Airlines
Deal found 4/28![American Airlines logo]()
$371
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:35 am
AVL
- ECP
1 stop3h 42m
Delta
Tue 8/116:00 am
ECP
- AVL
1 stop3h 42m
Delta
Deal found 4/30![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:10 am
TYS
- ECP
1 stop3h 15m
Southwest
Mon 8/107:05 am
ECP
- TYS
1 stop3h 50m
Southwest
Deal found 4/25![Southwest logo]()
$299
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:55 am
AVL
- ECP
1 stop7h 14m
United Airlines
Tue 10/2710:25 am
ECP
- AVL
1 stop5h 19m
United Airlines
Deal found 4/28![United Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:40 am
TYS
- ECP
1 stop3h 34m
Delta
Sun 6/215:08 pm
ECP
- TYS
1 stop5h 46m
Delta
Deal found 4/30![Delta logo]()
$299
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:55 pm
GSO
- ECP
1 stop5h 51m
American Airlines
Mon 5/187:21 am
ECP
- GSO
1 stop5h 36m
American Airlines
Deal found 4/26![American Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/132:35 pm
TYS
- ECP
1 stop8h 15m
Southwest
Thu 9/177:05 am
ECP
- TYS
1 stop3h 50m
Southwest
Deal found 4/29![Southwest logo]()
$304
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:08 am
RDU
- ECP
2 stops7h 50m
United Airlines
Wed 8/191:39 pm
ECP
- RDU
2 stops9h 08m
United Airlines
Deal found 4/30![United Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/257:46 pm
TYS
- ECP
1 stop4h 58m
Delta
Mon 6/296:00 am
ECP
- TYS
1 stop4h 09m
Delta
Deal found 4/28![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:40 am
TYS
- ECP
1 stop3h 55m
Southwest
Tue 7/287:40 am
ECP
- TYS
2 stops8h 20m
Southwest
Deal found 4/27![Southwest logo]()
$304
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:33 pm
ILM
- ECP
1 stop5h 17m
American Airlines
Sun 10/47:00 pm
ECP
- ILM
1 stop4h 19m
American Airlines
Deal found 4/26![American Airlines logo]()
$421
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:10 am
ORF
- ECP
1 stop5h 48m
United Airlines
Wed 8/1910:25 am
ECP
- ORF
1 stop5h 53m
United Airlines
Deal found 4/29![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/117:00 pm
RDU
- ECP
1 stop4h 58m
Delta
Sat 7/187:50 am
ECP
- RDU
1 stop5h 40m
Delta
Deal found 4/27![Delta logo]()
$307
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:27 pm
TRI
- ECP
1 stop4h 13m
American Airlines
Mon 6/16:45 pm
ECP
- TRI
1 stop4h 02m
American Airlines
Deal found 4/30![American Airlines logo]()
$427
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:55 pm
RDU
- ECP
1 stop4h 06m
Delta
Thu 5/284:54 pm
ECP
- RDU
1 stop6h 22m
Delta
Deal found 4/30![Delta logo]()
$307
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3010:55 am
CLT
- ECP
2 stops9h 05m
Southwest
Wed 6/37:15 am
ECP
- CLT
2 stops9h 30m
Southwest
Deal found 4/26![Southwest logo]()
$343
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/222:54 pm
GSO
- ECP
1 stop4h 56m
Delta
Sun 7/269:12 am
ECP
- GSO
1 stop5h 18m
Delta
Deal found 4/30![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:40 am
CLT
- ECP
1 stop3h 50m
Southwest
Thu 5/211:40 pm
ECP
- CLT
2 stops7h 00m
Southwest
Deal found 4/27![Southwest logo]()
$350
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/52:46 pm
GSO
- ECP
1 stop4h 40m
American Airlines
Sat 6/66:45 pm
ECP
- GSO
1 stop4h 13m
American Airlines
Deal found 4/28![American Airlines logo]()
$467
Last-minute flights from North Carolina to Panama CityDiscover last-minute flight deals from North Carolina to Panama City. Data last updated May 1, 2026 and is based on user searches.
Discover last-minute flight deals from North Carolina to Panama City. Data last updated May 1, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:05 am
TYS
- ECP
1 stop3h 25m
Southwest
Sat 5/2312:40 pm
ECP
- TYS
1 stop4h 50m
Southwest
Deal found 4/26![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:33 pm
TYS
- ECP
1 stop4h 28m
Delta
Mon 5/256:00 am
ECP
- TYS
1 stop4h 09m
Delta
Deal found 4/28![Delta logo]()
$263
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:12 pm
MYR
- ECP
1 stop6h 28m
American Airlines
Sat 5/306:45 pm
ECP
- MYR
1 stop4h 05m
American Airlines
Deal found 4/28![American Airlines logo]()
$311
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:30 am
TYS
- ECP
2 stops10h 55m
Southwest
Wed 5/277:15 am
ECP
- TYS
2 stops8h 55m
Southwest
Deal found 4/28![Southwest logo]()
$290
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/248:08 pm
RDU
- ECP
1 stop4h 32m
American Airlines
Wed 5/277:05 am
ECP
- RDU
1 stop4h 24m
American Airlines
Deal found 4/27![American Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:05 am
TYS
- ECP
1 stop3h 25m
Southwest
Tue 6/27:15 am
ECP
- TYS
1 stop3h 45m
Southwest
Deal found 4/26![Southwest logo]()
$249
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:20 pm
AVL
- ECP
1 stop6h 20m
American Airlines
Tue 6/26:45 pm
ECP
- AVL
1 stop4h 14m
American Airlines
Deal found 4/28![American Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:15 am
TYS
- ECP
2 stops11h 40m
Southwest
Wed 6/37:15 am
ECP
- TYS
2 stops8h 55m
Southwest
Deal found 4/29![Southwest logo]()
$259
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:59 pm
TYS
- ECP
1 stop4h 41m
American Airlines
Wed 6/36:45 pm
ECP
- TYS
1 stop4h 02m
American Airlines
Deal found 4/27![American Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:33 pm
TYS
- ECP
1 stop4h 55m
Delta
Thu 6/46:45 pm
ECP
- TYS
1 stop4h 11m
Delta
Deal found 4/28![Delta logo]()
$277
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:23 am
GSO
- ECP
1 stop4h 07m
Delta
Wed 6/39:19 am
ECP
- GSO
1 stop5h 01m
Delta
Deal found 4/30![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/315:40 am
TYS
- ECP
1 stop3h 50m
Delta
Tue 6/26:00 am
ECP
- TYS
1 stop4h 09m
Delta
Deal found 4/29![Delta logo]()
$294
One-way flights from North Carolina to Panama CitySearch for one-way flight options from North Carolina to Panama City. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
Search for one-way flight options from North Carolina to Panama City. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:40 am
TYS
- ECP
1 stop3h 34m
Delta
Deal found 4/29![Delta logo]()
$125
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:45 pm
TYS
- ECP
1 stop8h 20m
Southwest
Deal found 4/29![Southwest logo]()
$130
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/208:15 am
TYS
- ECP
2 stops11h 40m
Southwest
Deal found 4/29![Southwest logo]()
$144
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1911:55 am
TYS
- ECP
1 stop5h 28m
Delta
Deal found 4/29![Delta logo]()
$150
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:25 pm
RDU
- ECP
1 stop6h 15m
American Airlines
Deal found 4/27![American Airlines logo]()
$154
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/198:15 am
TYS
- ECP
2 stops11h 40m
Southwest
Deal found 4/28![Southwest logo]()
$155
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:10 pm
ORF
- ECP
1 stop4h 30m
American Airlines
Deal found 4/30![American Airlines logo]()
$160
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:30 am
TYS
- ECP
2 stops10h 55m
Southwest
Deal found 4/28![Southwest logo]()
$161
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:40 am
CLT
- ECP
1 stop3h 50m
Southwest
Deal found 4/29![Southwest logo]()
$163
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/241:25 pm
CLT
- ECP
1 stop8h 45m
Southwest
Deal found 4/27![Southwest logo]()
$168
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:28 pm
ORF
- ECP
1 stop5h 23m
Delta
Deal found 4/26![Delta logo]()
$174
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:44 pm
MYR
- ECP
1 stop3h 53m
American Airlines
Deal found 4/27![American Airlines logo]()
$174
Find flight deals from North Carolina to Panama City
Keep the following information in mind while searching for North Carolina to Panama City flight deals. Data was last updated May 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $249 (Southwest) |
One-way from | $125 (Delta) |
Popular in | November |
Cheapest in | August |
Average price | $394 |
Good round-trip deal | $381 or less |
Good one-way deal | $393 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from North Carolina to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
Use the filters below to find and compare flights from North Carolina to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Wed 5/27
5:59 pm-11:01 pm
1 stop6h 02m
Panama City NW Florida Beaches
Wed 6/3
6:00 am-11:09 am
1 stop4h 09m
$249
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Wed 5/27
8:15 am-6:55 pm
2 stops11h 40m
Panama City NW Florida Beaches
Wed 6/3
7:15 am-5:10 pm
2 stops8h 55m
$259
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Tue 6/23
7:35 am-10:54 am
1 stop4h 19m
Panama City NW Florida Beaches
Thu 6/25
7:41 am-1:19 pm
1 stop4h 38m
$274
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Thu 6/25
12:35 pm-8:10 pm
2 stops8h 35m
Panama City NW Florida Beaches
Tue 6/30
7:40 am-5:00 pm
2 stops8h 20m
$284
BlountvillePanama City
TRI - ECP
TRIECP
Blountville Tri Cities TN/VA
Fri 7/10
6:00 am-10:48 am
1 stop5h 48m
Panama City NW Florida Beaches
Tue 7/14
9:12 am-3:28 pm
1 stop5h 16m
$289
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Wed 6/3
8:15 am-6:55 pm
2 stops11h 40m
Panama City NW Florida Beaches
Sun 6/7
2:05 pm-9:15 pm
1 stop6h 10m
$289
AshevillePanama City
AVL - ECP
AVLECP
Asheville Regional
Thu 7/30
5:35 am-8:17 am
1 stop3h 42m
Panama City NW Florida Beaches
Thu 8/6
9:15 am-2:40 pm
1 stop4h 25m
$289
AshevillePanama City
AVL - ECP
AVLECP
Asheville Regional
Fri 7/31
5:35 am-8:17 am
1 stop3h 42m
Panama City NW Florida Beaches
Tue 8/11
6:00 am-10:42 am
1 stop3h 42m
$289
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Fri 7/10
6:40 am-9:35 am
1 stop3h 55m
Panama City NW Florida Beaches
Tue 7/14
7:40 am-12:05 pm
1 stop3h 25m
$299
Quickest round-trip
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Fri 8/7
7:10 am-9:25 am
1 stop3h 15m
Panama City NW Florida Beaches
Mon 8/10
7:05 am-11:55 am
1 stop3h 50m
$299
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from North Carolina to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from North Carolina with our price prediction graph.
TYS-ECP
AVL-ECP
RDU-ECP
GSO-ECP
MYR-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from North Carolina to Panama City
USNC-ECP
TYS-ECP
AVL-ECP
RDU-ECP
GSO-ECP
How far ahead should I book a flight from North Carolina to Panama City, Florida?
To ensure you get the cheapest price possible for a flight from North Carolina to Panama City, Florida, you should look to book at least 50 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from North Carolina to Panama City, Florida?
Currently, May is the cheapest month in which you can book a flight from North Carolina to Panama City, Florida (average of $116). Flying from North Carolina to Panama City, Florida in December is currently the most expensive (average of $288). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from NC to ECP?
Find hourly flight availability from North Carolina to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2026.
Unlike at noon, when flights are generally more expensive, you can save up to 15% on flights from North Carolina to Panama City, Florida by exploring options for tickets in the evening.
Related info for your journey
Find useful and relevant information for your journey from North Carolina to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsMexico Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for North Carolina to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from North Carolina to Panama City by cabin class
Find flights from North Carolina to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
North Carolina and Panama City flights
Browse other North Carolina and Panama City flight options. Last updated on May 1, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
North Carolina to Panama City flights
Consider these flights traveling from North Carolina to Panama City.
Top 3 airlines flying from North Carolina to Panama City
Discover the top 3 airlines that operate flights from North Carolina to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$158 | Average$412 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$252 | Average$382 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$313 | Average$407 | FlexibilityNo cancel fee | On-time63% |