$122+ Cheap flights from North Carolina to Panama City, FL (ECP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — ECP
Aug 29 — Sep 51
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from North Carolina to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from North Carolina to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from North Carolina to Panama CityExplore the most affordable flight options available from North Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.
Explore the most affordable flight options available from North Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/252:16 pm
TYS
- ECP
1 stop5h 19m
Delta
Tue 9/15:26 pm
ECP
- TYS
1 stop5h 26m
Delta
Deal found 7/28![Delta logo]()
$243
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:50 am
TYS
- ECP
1 stop5h 15m
Southwest
Sat 8/227:15 am
ECP
- TYS
2 stops11h 05m
Southwest
Deal found 7/24![Southwest logo]()
$248
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:13 pm
TYS
- ECP
1 stop3h 50m
Delta
Tue 9/227:35 am
ECP
- TYS
1 stop4h 46m
Delta
Deal found 7/27![Delta logo]()
$266
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:05 pm
TYS
- ECP
1 stop7h 55m
Southwest
Thu 8/277:05 am
ECP
- TYS
2 stops9h 05m
Southwest
Deal found 7/24![Southwest logo]()
$271
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:40 am
TYS
- ECP
1 stop3h 36m
Delta
Mon 9/217:35 am
ECP
- TYS
1 stop4h 46m
Delta
Deal found 7/26![Delta logo]()
$274
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:40 am
TYS
- ECP
1 stop3h 36m
Delta
Sun 9/136:00 am
ECP
- TYS
1 stop4h 23m
Delta
Deal found 7/28![Delta logo]()
$276
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:56 pm
MYR
- ECP
1 stop5h 29m
Delta
Thu 9/246:00 am
ECP
- MYR
1 stop3h 07m
Delta
Deal found 7/28![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:05 pm
TYS
- ECP
1 stop8h 00m
Southwest
Mon 9/287:05 am
ECP
- TYS
2 stops9h 05m
Southwest
Deal found 7/24![Southwest logo]()
$281
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:43 am
MYR
- ECP
1 stop4h 56m
American Airlines
Fri 9/111:32 pm
ECP
- MYR
1 stop4h 13m
American Airlines
Deal found 7/27![American Airlines logo]()
$283
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:50 am
TYS
- ECP
1 stop5h 49m
Delta
Mon 9/216:00 am
ECP
- TYS
1 stop4h 18m
Delta
Deal found 7/29![Delta logo]()
$286
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:14 pm
MYR
- ECP
1 stop4h 39m
American Airlines
Sat 10/176:43 pm
ECP
- MYR
1 stop4h 15m
American Airlines
Deal found 7/28![American Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:38 pm
TYS
- ECP
1 stop4h 30m
Delta
Fri 8/2811:31 am
ECP
- TYS
1 stop2h 59m
Delta
Deal found 7/26![Delta logo]()
$289
Best flights from North Carolina to Panama CityDiscover carefully curated flight deals from North Carolina to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2026.
Discover carefully curated flight deals from North Carolina to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2026.
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:40 am
TYS
- ECP
1 stop3h 34m
Delta
Sat 10/245:40 pm
ECP
- TYS
1 stop3h 42m
Delta
Deal found 7/27![Delta logo]()
$243
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:50 am
TYS
- ECP
2 stops9h 05m
Southwest
Sat 9/510:40 am
ECP
- TYS
1 stop6h 05m
Southwest
Deal found 7/26![Southwest logo]()
$276
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:43 am
MYR
- ECP
1 stop4h 56m
American Airlines
Fri 9/111:32 pm
ECP
- MYR
1 stop4h 13m
American Airlines
Deal found 7/27![American Airlines logo]()
$283
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:40 am
GSO
- ECP
1 stop7h 26m
United Airlines
Tue 9/11:47 pm
ECP
- GSO
1 stop6h 33m
United Airlines
Deal found 7/25![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:40 am
TYS
- ECP
1 stop3h 38m
Delta
Fri 9/256:19 pm
ECP
- TYS
1 stop4h 36m
Delta
Deal found 7/27![Delta logo]()
$276
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:10 am
TYS
- ECP
2 stops6h 40m
Southwest
Fri 8/286:00 am
ECP
- TYS
1 stop6h 25m
Southwest
Deal found 7/24![Southwest logo]()
$294
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:29 pm
TRI
- ECP
1 stop6h 11m
American Airlines
Sat 8/295:48 pm
ECP
- TRI
1 stop4h 11m
American Airlines
Deal found 7/25![American Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:19 pm
ORF
- ECP
1 stop4h 46m
Delta
Tue 9/2211:19 am
ECP
- ORF
1 stop5h 55m
Delta
Deal found 7/29![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1512:15 pm
ORF
- ECP
2 stops9h 20m
Southwest
Tue 9/2211:30 am
ECP
- ORF
1 stop4h 50m
Southwest
Deal found 7/29![Southwest logo]()
$314
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:00 pm
ORF
- ECP
1 stop6h 08m
Delta
Tue 12/85:15 pm
ECP
- ORF
1 stop6h 18m
Delta
Deal found 7/29![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:04 pm
AVL
- ECP
1 stop4h 48m
American Airlines
Sat 11/77:53 am
ECP
- AVL
1 stop4h 23m
American Airlines
Deal found 7/30![American Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:40 pm
ORF
- ECP
1 stop6h 30m
Southwest
Wed 9/97:45 am
ECP
- ORF
2 stops7h 10m
Southwest
Deal found 7/24![Southwest logo]()
$314
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:13 pm
TRI
- ECP
1 stop2h 55m
Delta
Fri 9/254:33 pm
ECP
- TRI
1 stop4h 47m
Delta
Deal found 7/27![Delta logo]()
$313
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:10 am
TYS
- ECP
2 stops6h 40m
Southwest
Mon 9/287:05 am
ECP
- TYS
2 stops9h 05m
Southwest
Deal found 7/24![Southwest logo]()
$315
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
TRI
- ECP
1 stop3h 16m
Delta
Wed 9/166:00 am
ECP
- TRI
1 stop5h 45m
Delta
Deal found 7/26![Delta logo]()
$313
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:15 am
RDU
- ECP
2 stops8h 55m
Southwest
Tue 9/19:10 am
ECP
- RDU
2 stops8h 00m
Southwest
Deal found 7/26![Southwest logo]()
$319
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:00 am
RDU
- ECP
2 stops8h 06m
United Airlines
Tue 9/16:30 am
ECP
- RDU
1 stop8h 29m
United Airlines
Deal found 7/25![United Airlines logo]()
$477
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:25 am
CLT
- ECP
1 stop3h 45m
Southwest
Fri 9/114:10 pm
ECP
- CLT
1 stop4h 45m
Southwest
Deal found 7/27![Southwest logo]()
$319
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:00 am
ILM
- ECP
1 stop5h 42m
Delta
Wed 9/25:26 pm
ECP
- ILM
1 stop3h 40m
Delta
Deal found 7/28![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:40 am
MYR
- ECP
2 stops9h 10m
Southwest
Sat 10/175:55 am
ECP
- MYR
2 stops10h 20m
Southwest
Deal found 7/28![Southwest logo]()
$324
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:45 am
AVL
- ECP
1 stop3h 46m
Delta
Wed 8/269:27 am
ECP
- AVL
1 stop2h 44m
Delta
Deal found 7/27![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/184:44 pm
ILM
- ECP
2 stops24h 54m
United Airlines
Tue 8/251:47 pm
ECP
- ILM
2 stops9h 10m
United Airlines
Deal found 7/27![United Airlines logo]()
$567
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:19 pm
AVL
- ECP
1 stop4h 46m
Delta
Tue 9/156:00 am
ECP
- AVL
1 stop4h 04m
Delta
Deal found 7/25![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:10 am
CLT
- ECP
2 stops8h 35m
Southwest
Wed 9/29:10 am
ECP
- CLT
2 stops11h 15m
Southwest
Deal found 7/27![Southwest logo]()
$325
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:22 pm
ILM
- ECP
1 stop4h 18m
American Airlines
Sun 8/166:57 pm
ECP
- ILM
1 stop3h 59m
American Airlines
Deal found 7/28![American Airlines logo]()
$551
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:45 am
AVL
- ECP
1 stop3h 31m
Delta
Sat 9/126:00 am
ECP
- AVL
1 stop4h 04m
Delta
Deal found 7/26![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/284:44 pm
ILM
- ECP
2 stops19h 20m
United Airlines
Tue 9/11:47 pm
ECP
- ILM
2 stops9h 10m
United Airlines
Deal found 7/27![United Airlines logo]()
$597
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1511:10 am
CLT
- ECP
1 stop4h 50m
Southwest
Thu 9/1710:00 am
ECP
- CLT
1 stop10h 55m
Southwest
Deal found 7/29![Southwest logo]()
$338
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/244:00 pm
GSO
- ECP
1 stop4h 36m
Delta
Mon 12/287:05 pm
ECP
- GSO
1 stop3h 49m
Delta
Deal found 7/26![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:55 am
MYR
- ECP
2 stops11h 20m
Southwest
Mon 9/147:05 am
ECP
- MYR
2 stops9h 30m
Southwest
Deal found 7/29![Southwest logo]()
$338
Last-minute flights from North Carolina to Panama CityDiscover last-minute flight deals from North Carolina to Panama City. Data last updated July 30, 2026 and is based on user searches.
Discover last-minute flight deals from North Carolina to Panama City. Data last updated July 30, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:50 am
TYS
- ECP
1 stop5h 15m
Southwest
Sat 8/227:15 am
ECP
- TYS
2 stops11h 05m
Southwest
Deal found 7/24![Southwest logo]()
$248
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:25 pm
TYS
- ECP
1 stop4h 15m
American Airlines
Mon 8/245:48 pm
ECP
- TYS
1 stop4h 10m
American Airlines
Deal found 7/25![American Airlines logo]()
$266
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:05 pm
TYS
- ECP
1 stop7h 55m
Southwest
Thu 8/277:05 am
ECP
- TYS
2 stops9h 05m
Southwest
Deal found 7/24![Southwest logo]()
$271
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:10 am
TYS
- ECP
2 stops6h 40m
Southwest
Mon 8/247:05 am
ECP
- TYS
2 stops9h 05m
Southwest
Deal found 7/25![Southwest logo]()
$276
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:38 pm
TYS
- ECP
1 stop4h 30m
Delta
Fri 8/2811:31 am
ECP
- TYS
1 stop2h 59m
Delta
Deal found 7/26![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:10 am
TYS
- ECP
2 stops6h 40m
Southwest
Fri 8/286:00 am
ECP
- TYS
1 stop6h 25m
Southwest
Deal found 7/24![Southwest logo]()
$294
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:29 pm
TRI
- ECP
1 stop6h 11m
American Airlines
Sat 8/295:48 pm
ECP
- TRI
1 stop4h 11m
American Airlines
Deal found 7/26![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:15 pm
AVL
- ECP
1 stop6h 25m
American Airlines
Mon 8/315:48 pm
ECP
- AVL
1 stop3h 54m
American Airlines
Deal found 7/28![American Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/252:16 pm
TYS
- ECP
1 stop5h 19m
Delta
Tue 9/15:26 pm
ECP
- TYS
1 stop5h 26m
Delta
Deal found 7/28![Delta logo]()
$243
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:23 pm
ORF
- ECP
1 stop4h 17m
American Airlines
Mon 8/315:48 pm
ECP
- ORF
1 stop4h 20m
American Airlines
Deal found 7/26![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:26 pm
RDU
- ECP
1 stop4h 14m
American Airlines
Mon 8/316:40 am
ECP
- RDU
1 stop3h 39m
American Airlines
Deal found 7/26![American Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:50 am
TYS
- ECP
2 stops9h 05m
Southwest
Sat 9/58:15 am
ECP
- TYS
2 stops8h 30m
Southwest
Deal found 7/26![Southwest logo]()
$305
One-way flights from North Carolina to Panama CitySearch for one-way flight options from North Carolina to Panama City. Find affordable one-way fares based on user searches. Data last updated July 30, 2026.
Search for one-way flight options from North Carolina to Panama City. Find affordable one-way fares based on user searches. Data last updated July 30, 2026.
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:05 pm
TYS
- ECP
1 stop5h 35m
American Airlines
Deal found 7/27![American Airlines logo]()
$122
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:55 pm
TYS
- ECP
2 stops7h 35m
Southwest
Deal found 7/29![Southwest logo]()
$127
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am
MYR
- ECP
1 stop3h 16m
Delta
Deal found 7/25![Delta logo]()
$153
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:55 am
RDU
- ECP
1 stop5h 05m
Southwest
Deal found 7/28![Southwest logo]()
$155
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:25 pm
TYS
- ECP
1 stop5h 00m
Delta
Deal found 7/26![Delta logo]()
$155
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:50 am
CLT
- ECP
1 stop5h 45m
Southwest
Deal found 7/25![Southwest logo]()
$158
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/88:05 am
TYS
- ECP
2 stops11h 10m
Southwest
Deal found 7/24![Southwest logo]()
$179
This KAYAK deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/214:54 pm
RDU
- ECP
1 stop5h 09m
Delta
Deal found 7/28![Delta logo]()
$184
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:50 am
CLT
- ECP
1 stop5h 45m
Southwest
Deal found 7/28![Southwest logo]()
$190
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:40 am
TYS
- ECP
1 stop3h 36m
Delta
Deal found 7/26![Delta logo]()
$190
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:33 pm
ORF
- ECP
1 stop4h 45m
Delta
Deal found 7/27![Delta logo]()
$199
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:35 am
CLT
- ECP
2 stops11h 30m
Southwest
Deal found 7/24![Southwest logo]()
$201
Find flight deals from North Carolina to Panama City
Keep the following information in mind while searching for North Carolina to Panama City flight deals. Data was last updated July 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $243 (Delta) |
One-way from | $122 (American Airlines) |
Popular in | November |
Cheapest in | August |
Average price | $436 |
Good round-trip deal | $480 or less |
Good one-way deal | $490 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from North Carolina to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from North Carolina to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Sat 10/10
5:40 am-8:14 am
1 stop3h 34m
Panama City NW Florida Beaches
Sat 10/24
5:40 pm-10:22 pm
1 stop3h 42m
$243
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Sat 8/29
6:50 am-2:55 pm
2 stops9h 05m
Panama City NW Florida Beaches
Sat 9/5
10:40 am-5:45 pm
1 stop6h 05m
$276
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Sat 9/19
5:40 am-8:18 am
1 stop3h 38m
Panama City NW Florida Beaches
Fri 9/25
6:19 pm-11:55 pm
1 stop4h 36m
$276
Myrtle BeachPanama City
MYR - ECP
MYRECP
Myrtle Beach Intl
Sun 9/6
6:43 am-10:39 am
1 stop4h 56m
Panama City NW Florida Beaches
Fri 9/11
1:32 pm-6:45 pm
1 stop4h 13m
$283
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Fri 8/21
7:10 am-12:50 pm
2 stops6h 40m
Panama City NW Florida Beaches
Fri 8/28
6:00 am-1:25 pm
1 stop6h 25m
$294
BlountvillePanama City
TRI - ECP
TRIECP
Blountville Tri Cities TN/VA
Sat 8/22
5:29 pm-10:40 pm
1 stop6h 11m
Panama City NW Florida Beaches
Sat 8/29
5:48 pm-10:59 pm
1 stop4h 11m
$299
NorfolkPanama City
ORF - ECP
ORFECP
Norfolk
Tue 9/15
7:19 pm-11:05 pm
1 stop4h 46m
Panama City NW Florida Beaches
Tue 9/22
11:19 am-6:14 pm
1 stop5h 55m
$309
NorfolkPanama City
ORF - ECP
ORFECP
Norfolk
Wed 12/2
3:00 pm-8:08 pm
1 stop6h 08m
Panama City NW Florida Beaches
Tue 12/8
5:15 pm-12:33 am
1 stop6h 18m
$309
BlountvillePanama City
TRI - ECP
TRIECP
Blountville Tri Cities TN/VA
Sat 9/19
5:13 pm-7:08 pm
1 stop2h 55m
Panama City NW Florida Beaches
Fri 9/25
4:33 pm-10:20 pm
1 stop4h 47m
$313
BlountvillePanama City
TRI - ECP
TRIECP
Blountville Tri Cities TN/VA
Wed 9/9
6:00 am-8:16 am
1 stop3h 16m
Panama City NW Florida Beaches
Wed 9/16
6:00 am-12:45 pm
1 stop5h 45m
$313
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from North Carolina to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from North Carolina with our price prediction graph.
TYS-ECP
MYR-ECP
RDU-ECP
CLT-ECP
ORF-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from North Carolina to Panama City
USNC-ECP
TYS-ECP
MYR-ECP
RDU-ECP
CLT-ECP
What is the cheapest month to book a flight from North Carolina to Panama City, Florida?
Currently, September is the cheapest month in which you can book a flight from North Carolina to Panama City, Florida (average of $349). Flying from North Carolina to Panama City, Florida in April is currently the most expensive (average of $497). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from NC to ECP?
Find hourly flight availability from North Carolina to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2026.
Unlike at noon, when flights are generally more expensive, you can save up to 9% on flights from North Carolina to Panama City, Florida by exploring options for tickets in the morning.
How much does it cost to fly round-trip from North Carolina to Panama City, Florida?
Airfare is below average for this route at the moment.
North Carolina to Panama City, Florida flights typically cost between $449 and $645 in August.The cheapest round-trip price found within the last 5 days was $315 on Southwest (Aug 24-Aug 31).
How far ahead should I book a flight from North Carolina to Panama City, Florida?
To ensure you get the cheapest price possible for a flight from North Carolina to Panama City, Florida, you should look to book at least 32 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Related info for your journey
Find useful and relevant information for your journey from North Carolina to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsMexico Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Panama City flight routes
Popular flights
Top destinations
Alternative routes for North Carolina to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from North Carolina to Panama City by cabin class
Find flights from North Carolina to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
North Carolina and Panama City flights
Browse other North Carolina and Panama City flight options. Last updated on July 30, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
North Carolina to Panama City flights
Consider these flights traveling from North Carolina to Panama City.
Top 3 airlines flying from North Carolina to Panama City
Discover the top 3 airlines that operate flights from North Carolina to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$158 | Average$401 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$276 | Average$449 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$313 | Average$436 | FlexibilityNo cancel fee | On-time63% |