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Panama City

$174+ Cheap flights from Myrtle Beach to Panama City, FL (MYR - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/1. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — ECP
May 30 — Jun 61
Sat 5/30
Sat 6/6
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Panama City

Cheapest flights from Myrtle Beach to Panama City
Explore the most affordable flight options available from Myrtle Beach to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:12 pm
MYR
-
ECP
1 stop6h 28m
American Airlines
Sat 5/306:45 pm
ECP
-
MYR
1 stop4h 05m
American Airlines
Deal found 4/28$311
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:55 pm
MYR
-
ECP
1 stop4h 33m
Delta
Mon 6/86:00 am
ECP
-
MYR
1 stop3h 44m
Delta
Deal found 4/28$329
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:15 pm
MYR
-
ECP
1 stop6h 21m
Delta
Thu 12/247:45 am
ECP
-
MYR
1 stop4h 50m
Delta
Deal found 4/28$347
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:45 pm
MYR
-
ECP
1 stop6h 10m
Southwest
Sat 6/138:30 am
ECP
-
MYR
1 stop6h 40m
Southwest
Deal found 4/29$359
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am
MYR
-
ECP
1 stop3h 17m
Delta
Sat 12/197:45 am
ECP
-
MYR
1 stop4h 50m
Delta
Deal found 4/28$367
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/218:41 pm
MYR
-
ECP
1 stop3h 59m
American Airlines
Sat 6/276:45 pm
ECP
-
MYR
1 stop4h 04m
American Airlines
Deal found 4/28$371
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:55 am
MYR
-
ECP
2 stops11h 15m
Southwest
Mon 9/141:30 pm
ECP
-
MYR
1 stop4h 50m
Southwest
Deal found 4/26$372
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:43 am
MYR
-
ECP
1 stop5h 54m
Delta
Tue 5/196:00 am
ECP
-
MYR
1 stop3h 39m
Delta
Deal found 4/27$373
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:30 pm
MYR
-
ECP
2 stops7h 30m
Southwest
Sun 9/1312:50 pm
ECP
-
MYR
1 stop6h 50m
Southwest
Deal found 4/26$382
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1211:00 am
MYR
-
ECP
2 stops12h 47m
Delta
Tue 12/227:45 am
ECP
-
MYR
1 stop6h 09m
Delta
Deal found 4/28$392

Find flight deals from Myrtle Beach to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$311
(American Airlines)

One-way from

$174
(American Airlines)

Popular in

March

Cheapest in

September
Provider with most accurate pricing for Myrtle Beach Intl-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Panama City NW Florida Beaches flights.
Search Deals
From Myrtle Beach Intl to Panama City NW Florida Beaches
Search Deals
One-way flight from Myrtle Beach Intl to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($107 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($17 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sat 6/6

5:45 pm-10:55 pm

1 stop6h 10m

Panama City NW Florida Beaches

Sat 6/13

8:30 am-4:10 pm

1 stop6h 40m

$359

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sun 6/21

8:41 pm-11:40 pm

1 stop3h 59m

Panama City NW Florida Beaches

Sat 6/27

6:45 pm-11:50 pm

1 stop4h 05m

$371

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Tue 9/8

11:00 am-8:30 pm

2 stops10h 30m

Panama City NW Florida Beaches

Tue 9/15

7:45 am-5:40 pm

2 stops8h 55m

$374

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Tue 5/12

4:05 pm-6:55 pm

1 stop3h 50m

Panama City NW Florida Beaches

Tue 5/19

7:55 am-8:30 pm

2 stops11h 35m

$413

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Wed 5/13

7:55 pm-11:01 pm

1 stop4h 06m

Panama City NW Florida Beaches

Sun 5/17

6:45 pm-11:58 pm

1 stop4h 13m

$459
Quickest round-trip

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Fri 5/29

6:00 am-8:30 am

1 stop3h 30m

Panama City NW Florida Beaches

Mon 6/1

7:41 am-12:40 pm

1 stop3h 59m

$461

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Mon 5/11

10:55 am-3:35 pm

1 stop5h 40m

Panama City NW Florida Beaches

Fri 5/15

6:40 am-6:45 pm

2 stops11h 05m

$468
Cheapest one-way

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sat 8/1

3:00 pm-10:55 pm

2 stops8h 55m

$220
Quickest one-way

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Fri 5/15

11:43 am-2:04 pm

1 stop3h 21m

$230

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Fri 5/15

10:55 am-9:40 pm

2 stops11h 45m

$245

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/27

Sorted by cheapest first

Compare providers for flights from Myrtle Beach to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Panama City in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Panama City

How much does it cost to fly round-trip from Myrtle Beach to Panama City, Florida?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated April 30, 2026.
Get a feel of what it's like to fly with Delta from Myrtle Beach to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,464 reviews

Crew

8.5

Food

7.2

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
8,464 reviews
Delta
7.9
Good
8,464 reviews

Crew

8.5

Food

7.2

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to Panama City, Florida?

    A quick flight from Myrtle Beach to Panama City, Florida can take about 3h 59m. Southwest provides one of the quickest options available for as low as $371. Myrtle Beach and Panama City, Florida are separated by a distance of 463 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Myrtle Beach to Panama City, Florida round-trip?

    Delta, at $207, was found to be the cheapest airline from Myrtle Beach to Panama City, Florida.. Delta is priced at 37% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Myrtle Beach to Panama City that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Panama City.

  • Can I find deals for business class flights from Myrtle Beach to Panama City?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Panama City?

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Top airline flying from Myrtle Beach to Panama City

Discover the top airline that operate flights from Myrtle Beach to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$207Average$306FlexibilityNo cancel feeOn-timeN/A

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