$257+ Cheap flights from Myrtle Beach to Panama City, FL (MYR - ECP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — ECP
Nov 23 — Nov 301
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Myrtle Beach to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Myrtle Beach to Panama CityExplore the most affordable flight options available from Myrtle Beach to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 24, 2026.
Explore the most affordable flight options available from Myrtle Beach to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 24, 2026.
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:58 pm -
1 stop5h 26m
Thu 11/196:00 am -
1 stop3h 07m
Deal found 10/23![Delta logo]()
$257
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:51 pm -
1 stop5h 33m
Fri 11/276:00 am -
1 stop3h 07m
Deal found 10/20![Delta logo]()
$430
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:58 pm -
1 stop5h 26m
Fri 11/276:00 am -
1 stop3h 07m
Deal found 10/20![Delta logo]()
$498
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:58 pm -
1 stop5h 26m
Sat 11/286:00 am -
1 stop3h 29m
Deal found 10/20![Delta logo]()
$598
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am -
1 stop3h 14m
Sun 11/86:00 am -
1 stop3h 07m
Deal found 10/24![Delta logo]()
$663
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:05 am -
2 stops15h 35m
Fri 11/277:55 am -
1 stop4h 05m
Deal found 10/20![Southwest logo]()
$698
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:55 pm -
1 stop6h 00m
Thu 10/2910:55 am -
1 stop9h 55m
Deal found 10/21![Southwest logo]()
$701
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:20 am -
2 stops13h 15m
Fri 11/277:55 am -
1 stop4h 05m
Deal found 10/20![Southwest logo]()
$723
Best flights from Myrtle Beach to Panama CityDiscover carefully curated flight deals from Myrtle Beach to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 24, 2026.
Discover carefully curated flight deals from Myrtle Beach to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 24, 2026.
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:58 pm -
1 stop5h 26m
Thu 11/196:00 am -
1 stop3h 07m
Deal found 10/23![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:20 am -
2 stops13h 15m
Fri 11/277:55 am -
1 stop4h 05m
Deal found 10/20![Southwest logo]()
$723
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:51 pm -
1 stop5h 33m
Fri 11/276:00 am -
1 stop3h 07m
Deal found 10/20![Delta logo]()
$430
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:58 pm -
1 stop5h 26m
Sat 11/286:00 am -
1 stop3h 29m
Deal found 10/20![Delta logo]()
$598
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:05 am -
2 stops15h 35m
Fri 11/2711:25 am -
2 stops6h 30m
Deal found 10/20![Southwest logo]()
$822
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:45 am -
1 stop10h 50m
Sun 11/87:55 am -
1 stop4h 05m
Deal found 10/24![Southwest logo]()
$847
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:45 am -
1 stop10h 50m
Sun 11/87:55 am -
1 stop4h 05m
Deal found 10/24![Southwest logo]()
$946
Last-minute flights from Myrtle Beach to Panama CityDiscover last-minute flight deals from Myrtle Beach to Panama City. Data last updated October 24, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Panama City. Data last updated October 24, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:25 am -
1 stop3h 45m
Thu 10/2910:55 am -
2 stops9h 35m
Deal found 10/21![Southwest logo]()
$701
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am -
1 stop3h 14m
Sun 11/86:00 am -
1 stop3h 07m
Deal found 10/24![Delta logo]()
$663
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:58 pm -
1 stop5h 26m
Thu 11/196:00 am -
1 stop3h 07m
Deal found 10/23![Delta logo]()
$257
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:51 pm -
1 stop5h 33m
Fri 11/276:00 am -
1 stop3h 07m
Deal found 10/20![Delta logo]()
$430
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:20 am -
2 stops13h 15m
Fri 11/277:55 am -
1 stop4h 05m
Deal found 10/20![Southwest logo]()
$723
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:58 pm -
1 stop5h 26m
Fri 11/276:00 am -
1 stop3h 07m
Deal found 10/20![Delta logo]()
$498
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:58 pm -
1 stop5h 26m
Sat 11/286:00 am -
1 stop3h 29m
Deal found 10/20![Delta logo]()
$598
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:05 am -
2 stops15h 35m
Fri 11/277:55 am -
1 stop4h 05m
Deal found 10/20![Southwest logo]()
$698
One-way flights from Myrtle Beach to Panama CitySearch for one-way flight options from Myrtle Beach to Panama City. Find affordable one-way fares based on user searches. Data last updated October 24, 2026.
Search for one-way flight options from Myrtle Beach to Panama City. Find affordable one-way fares based on user searches. Data last updated October 24, 2026.
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:55 pm -
1 stop6h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Southwest logo]()
$336
Find flight deals from Myrtle Beach to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $257 (Delta) |
Popular in | March |
Cheapest in | June |
Average price | $411 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 24, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Tue 11/17
6:58 pm-11:24 pm
1 stop5h 26m
Panama City NW Florida Beaches
Thu 11/19
6:00 am-10:07 am
1 stop3h 07m
$257
Quickest round-trip
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Fri 10/30
3:55 pm-8:55 pm
1 stop6h 00m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$336
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Mon 11/23
6:51 pm-11:24 pm
1 stop5h 33m
Panama City NW Florida Beaches
Fri 11/27
6:00 am-10:07 am
1 stop3h 07m
$430
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Tue 11/24
6:58 pm-11:24 pm
1 stop5h 26m
Panama City NW Florida Beaches
Sat 11/28
6:00 am-10:29 am
1 stop3h 29m
$598
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Mon 11/23
8:20 am-8:35 pm
2 stops13h 15m
Panama City NW Florida Beaches
Fri 11/27
7:55 am-1:00 pm
1 stop4h 05m
$723
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Tue 11/24
8:05 am-10:40 pm
2 stops15h 35m
Panama City NW Florida Beaches
Fri 11/27
11:25 am-6:55 pm
2 stops6h 30m
$822
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Fri 11/6
10:45 am-8:35 pm
1 stop10h 50m
Panama City NW Florida Beaches
Sun 11/8
7:55 am-1:00 pm
1 stop4h 05m
$847
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Thu 11/5
10:45 am-8:35 pm
1 stop10h 50m
Panama City NW Florida Beaches
Sun 11/8
7:55 am-1:00 pm
1 stop4h 05m
$946
Sorted by cheapest first
Compare providers for flights from Myrtle Beach to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Panama City in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Myrtle Beach with our price prediction graph.
MYR-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Panama City
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 24, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Myrtle Beach to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Comfort
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Comfort
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Myrtle Beach
Panama City flight routes
Popular flights
Alternative routes for Myrtle Beach to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Myrtle Beach to Panama City by cabin class
Find flights from Myrtle Beach to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Myrtle Beach and Panama City flights
Browse other Myrtle Beach and Panama City flight options. Last updated on October 24, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on October 24, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Myrtle Beach to Panama City
Discover the top 2 airlines that operate flights from Myrtle Beach to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$264 | Average$432 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$286 | Average$346 | FlexibilityNo cancel fee | On-timeN/A |