$179+ Cheap flights from Myrtle Beach to Panama City, FL (MYR - ECP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — ECP
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Myrtle Beach to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Panama City
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Cheapest flights from Myrtle Beach to Panama CityExplore the most affordable flight options available from Myrtle Beach to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Myrtle Beach to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:58 pm -
1 stop5h 20m
Mon 11/26:00 am -
1 stop3h 07m
Deal found 9/9![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:15 am -
2 stops10h 10m
Mon 11/27:55 am -
1 stop4h 05m
Deal found 9/9![Southwest logo]()
$304
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:29 pm -
1 stop4h 11m
Tue 10/208:05 am -
1 stop4h 33m
Deal found 9/6![American Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:25 am -
2 stops11h 20m
Tue 10/207:40 am -
1 stop4h 50m
Deal found 9/6![Southwest logo]()
$360
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:58 pm -
1 stop5h 20m
Fri 10/164:30 pm -
1 stop5h 27m
Deal found 9/9![Delta logo]()
$472
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:00 am -
1 stop3h 16m
Sat 9/266:00 am -
1 stop3h 13m
Deal found 9/7![Delta logo]()
$489
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:50 am -
2 stops11h 25m
Sat 9/267:45 am -
1 stop4h 00m
Deal found 9/7![Southwest logo]()
$517
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:12 pm -
1 stop4h 41m
Fri 10/166:42 pm -
2 stops14h 51m
Deal found 9/9![American Airlines logo]()
$563
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:55 pm -
1 stop6h 00m
Mon 10/126:25 am -
2 stops14h 05m
Deal found 9/5![Southwest logo]()
$584
Best flights from Myrtle Beach to Panama CityDiscover carefully curated flight deals from Myrtle Beach to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Myrtle Beach to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:58 pm -
1 stop5h 20m
Mon 11/26:00 am -
1 stop3h 07m
Deal found 9/9![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:15 am -
2 stops10h 10m
Mon 11/27:00 am -
2 stops12h 00m
Deal found 9/9![Southwest logo]()
$325
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:44 pm -
1 stop4h 03m
Sat 11/287:25 am -
1 stop3h 52m
Deal found 9/5![American Airlines logo]()
$632
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:25 am -
2 stops11h 20m
Tue 10/207:40 am -
2 stops9h 20m
Deal found 9/6![Southwest logo]()
$365
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:58 pm -
1 stop5h 20m
Fri 10/164:30 pm -
1 stop5h 27m
Deal found 9/9![Delta logo]()
$472
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:56 pm -
1 stop3h 07m
Mon 10/126:00 am -
1 stop3h 07m
Deal found 9/5![Delta logo]()
$489
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:50 am -
2 stops11h 25m
Sat 9/267:15 am -
2 stops10h 50m
Deal found 9/7![Southwest logo]()
$522
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:00 am -
1 stop3h 16m
Sat 9/266:00 am -
1 stop3h 13m
Deal found 9/7![Delta logo]()
$489
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:55 pm -
1 stop6h 00m
Mon 10/126:25 am -
2 stops14h 05m
Deal found 9/5![Southwest logo]()
$584
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/283:39 pm -
1 stop3h 26m
Fri 1/11:59 pm -
1 stop6h 23m
Deal found 9/8![Delta logo]()
$599
Last-minute flights from Myrtle Beach to Panama CityDiscover last-minute flight deals from Myrtle Beach to Panama City. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Panama City. Data last updated September 10, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:00 am -
1 stop3h 16m
Sat 9/266:00 am -
1 stop3h 13m
Deal found 9/7![Delta logo]()
$489
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:50 am -
2 stops11h 25m
Sat 9/267:45 am -
1 stop4h 00m
Deal found 9/7![Southwest logo]()
$517
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:55 pm -
1 stop6h 00m
Mon 10/126:25 am -
2 stops14h 05m
Deal found 9/5![Southwest logo]()
$584
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:58 pm -
1 stop5h 20m
Fri 10/164:30 pm -
1 stop5h 27m
Deal found 9/9![Delta logo]()
$472
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:12 pm -
1 stop4h 41m
Fri 10/166:42 pm -
2 stops14h 51m
Deal found 9/9![American Airlines logo]()
$563
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:29 pm -
1 stop4h 11m
Tue 10/208:05 am -
1 stop4h 33m
Deal found 9/6![American Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:25 am -
2 stops11h 20m
Tue 10/207:40 am -
1 stop4h 50m
Deal found 9/6![Southwest logo]()
$360
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:58 pm -
1 stop5h 20m
Mon 11/26:00 am -
1 stop3h 07m
Deal found 9/9![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:15 am -
2 stops10h 10m
Mon 11/27:55 am -
1 stop4h 05m
Deal found 9/9![Southwest logo]()
$304
One-way flights from Myrtle Beach to Panama CitySearch for one-way flight options from Myrtle Beach to Panama City. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Myrtle Beach to Panama City. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:12 pm -
1 stop4h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![American Airlines logo]()
$179
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/98:00 am -
2 stops11h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Southwest logo]()
$260
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:40 am -
2 stops9h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Southwest logo]()
$283
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/95:25 pm -
3 stops41h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![United Airlines logo]()
$790
Find flight deals from Myrtle Beach to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $279 (Delta) |
One-way from | $179 (American Airlines) |
Popular in | March |
Cheapest in | June |
Average price | $345 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Sat 10/17
8:12 pm-11:53 pm
1 stop4h 41m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$179
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Tue 3/9
6:24 pm-11:49 pm
1 stop6h 25m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$179
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Tue 3/9
8:00 am-6:10 pm
2 stops11h 10m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$260
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Thu 10/29
6:58 pm-11:18 pm
1 stop5h 20m
Panama City NW Florida Beaches
Mon 11/2
6:00 am-10:07 am
1 stop3h 07m
$279
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Sat 10/17
11:40 am-7:55 pm
2 stops9h 15m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$283
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Thu 10/29
6:15 am-3:25 pm
2 stops10h 10m
Panama City NW Florida Beaches
Mon 11/2
7:00 am-8:00 pm
2 stops12h 00m
$325
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Tue 10/13
10:25 am-8:45 pm
2 stops11h 20m
Panama City NW Florida Beaches
Tue 10/20
7:40 am-6:00 pm
2 stops9h 20m
$365
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Fri 10/9
6:58 pm-11:18 pm
1 stop5h 20m
Panama City NW Florida Beaches
Fri 10/16
4:30 pm-10:57 pm
1 stop5h 27m
$472
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Mon 10/5
6:56 pm-9:03 pm
1 stop3h 07m
Panama City NW Florida Beaches
Mon 10/12
6:00 am-10:07 am
1 stop3h 07m
$489
Myrtle BeachPanama City
MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches
MYRECP
Myrtle Beach Intl
Tue 9/22
6:00 am-8:16 am
1 stop3h 16m
Panama City NW Florida Beaches
Sat 9/26
6:00 am-10:13 am
1 stop3h 13m
$489
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Myrtle Beach with our price prediction graph.
MYR-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Panama City
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 10, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Myrtle Beach to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Entertainment
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Comfort
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Overall
7.8
Entertainment
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Comfort
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Overall
7.8
Entertainment
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Comfort
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsMexico Beach
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Myrtle Beach and Panama City flights
Browse other Myrtle Beach and Panama City flight options. Last updated on September 10, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
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Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Myrtle Beach to Panama City
Discover the top 2 airlines that operate flights from Myrtle Beach to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$264 | Average$432 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$286 | Average$346 | FlexibilityNo cancel fee | On-timeN/A |