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Panama City

$140+ Cheap flights from Myrtle Beach to Panama City, FL (MYR - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — ECP
Aug 28 — Sep 41
Fri 8/28
Fri 9/4
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Panama City

Cheapest flights from Myrtle Beach to Panama City
Explore the most affordable flight options available from Myrtle Beach to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.

This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:56 pm
MYR
-
ECP
1 stop5h 29m
Delta
Thu 9/246:00 am
ECP
-
MYR
1 stop3h 07m
Delta
Deal found 7/28$279
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:43 am
MYR
-
ECP
1 stop4h 56m
American Airlines
Fri 9/111:32 pm
ECP
-
MYR
1 stop4h 13m
American Airlines
Deal found 7/27$283
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:14 pm
MYR
-
ECP
1 stop4h 39m
American Airlines
Sat 10/176:43 pm
ECP
-
MYR
1 stop4h 15m
American Airlines
Deal found 7/28$289
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:56 pm
MYR
-
ECP
1 stop3h 07m
Delta
Thu 9/246:00 am
ECP
-
MYR
1 stop3h 07m
Delta
Deal found 7/28$304
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:33 pm
MYR
-
ECP
1 stop4h 07m
American Airlines
Sat 8/295:48 pm
ECP
-
MYR
1 stop3h 50m
American Airlines
Deal found 7/26$314
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/69:20 am
MYR
-
ECP
2 stops12h 05m
Southwest
Fri 9/117:05 am
ECP
-
MYR
1 stop6h 40m
Southwest
Deal found 7/27$316
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:56 pm
MYR
-
ECP
1 stop5h 29m
Delta
Sat 9/266:00 am
ECP
-
MYR
1 stop3h 13m
Delta
Deal found 7/28$318
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:40 am
MYR
-
ECP
2 stops9h 10m
Southwest
Sat 10/175:55 am
ECP
-
MYR
2 stops10h 20m
Southwest
Deal found 7/28$324
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:56 pm
MYR
-
ECP
1 stop5h 29m
Delta
Tue 9/225:30 pm
ECP
-
MYR
1 stop4h 58m
Delta
Deal found 7/26$325
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:56 pm
MYR
-
ECP
1 stop3h 07m
Delta
Fri 9/254:33 pm
ECP
-
MYR
1 stop5h 55m
Delta
Deal found 7/28$329
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:15 pm
MYR
-
ECP
1 stop6h 25m
American Airlines
Sun 8/236:57 pm
ECP
-
MYR
1 stop3h 53m
American Airlines
Deal found 7/28$338

Find flight deals from Myrtle Beach to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$279
(Delta)

One-way from

$140
(American Airlines)

Popular in

September

Cheapest in

June

Average price

$346
Provider with most accurate pricing for Myrtle Beach Intl-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Panama City NW Florida Beaches flights.
Search Deals
From Myrtle Beach Intl to Panama City NW Florida Beaches
Search Deals
One-way flight from Myrtle Beach Intl to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sun 9/6

6:43 am-10:39 am

1 stop4h 56m

Panama City NW Florida Beaches

Fri 9/11

1:32 pm-6:45 pm

1 stop4h 13m

$283

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Mon 9/21

6:56 pm-11:25 pm

1 stop5h 29m

Panama City NW Florida Beaches

Thu 9/24

6:00 am-10:07 am

1 stop3h 07m

$305

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sun 9/6

9:20 am-8:25 pm

2 stops12h 05m

Panama City NW Florida Beaches

Fri 9/11

7:05 am-2:45 pm

1 stop6h 40m

$316

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sat 10/10

11:40 am-7:50 pm

2 stops9h 10m

Panama City NW Florida Beaches

Sat 10/17

5:55 am-5:15 pm

2 stops10h 20m

$324

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Thu 9/17

6:56 pm-11:25 pm

1 stop5h 29m

Panama City NW Florida Beaches

Thu 9/24

6:20 pm-11:28 pm

1 stop4h 08m

$329

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sat 8/15

11:55 am-6:05 pm

1 stop7h 10m

Panama City NW Florida Beaches

Wed 8/19

11:30 am-7:20 pm

1 stop6h 50m

$345
Quickest round-trip

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Wed 9/16

6:58 pm-11:05 pm

1 stop5h 07m

Panama City NW Florida Beaches

Mon 9/21

6:00 am-10:07 am

1 stop3h 07m

$384

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sun 8/9

7:02 pm-11:30 pm

1 stop5h 28m

Panama City NW Florida Beaches

Thu 8/13

6:51 pm-11:30 pm

1 stop3h 39m

$469
Cheapest one-way

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Thu 10/15

8:14 pm-11:53 pm

1 stop4h 39m

$140
Quickest one-way

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Thu 10/15

6:00 am-8:14 am

1 stop3h 14m

$153

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/24

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

Compare providers for flights from Myrtle Beach to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Panama City in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 29, 2026.
Get a feel of what it's like to fly with Delta from Myrtle Beach to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,482 reviews

Boarding

8.1

Comfort

7.8

Food

7.2

Overall

7.8

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
4.0
Okay

Joel,May 2026

ATL - JAX

The flight was delivered 50 minutes and taxing took what felt like 20 minutes to takeoff.
Delta
7.8
Good
8,482 reviews
Delta
7.8
Good
8,482 reviews

Boarding

8.1

Comfort

7.8

Food

7.2

Overall

7.8

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
4.0
Okay

Joel,May 2026

ATL - JAX

The flight was delivered 50 minutes and taxing took what felt like 20 minutes to takeoff.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to Panama City, Florida?

    A quick flight from Myrtle Beach to Panama City, Florida can take about 4h 56m. American Airlines provides one of the quickest options available for as low as $283. Myrtle Beach and Panama City, Florida are separated by a distance of 463 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Myrtle Beach to Panama City, Florida round-trip?

    Delta, at $286, was found to be the cheapest airline from Myrtle Beach to Panama City, Florida.. Delta is priced at 28% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Myrtle Beach to Panama City that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Panama City.

  • Can I find deals for business class flights from Myrtle Beach to Panama City?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
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Alternative routes for Myrtle Beach to Panama City

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Top airline flying from Myrtle Beach to Panama City

Discover the top airline that operate flights from Myrtle Beach to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$286Average$346FlexibilityNo cancel feeOn-timeN/A

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