$190+ Cheap flights from Greenville to Panama City, FL (GSP - ECP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — ECP
Oct 19 — Oct 261
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to Panama City
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Cheapest flights from Greenville to Panama CityExplore the most affordable flight options available from Greenville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
Explore the most affordable flight options available from Greenville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:33 pm -
1 stop4h 20m
Sat 10/106:42 pm -
1 stop3h 39m
Deal found 9/15![American Airlines logo]()
$245
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:40 am -
1 stop3h 34m
Sat 11/76:00 am -
1 stop3h 01m
Deal found 9/17![Delta logo]()
$291
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:40 am -
1 stop3h 34m
Mon 11/26:00 am -
1 stop3h 01m
Deal found 9/17![Delta logo]()
$301
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:19 pm -
1 stop5h 05m
Sun 11/156:55 pm -
1 stop3h 58m
Deal found 9/16![Delta logo]()
$328
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:40 am -
1 stop3h 34m
Sun 10/114:30 pm -
1 stop5h 21m
Deal found 9/16![Delta logo]()
$331
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:12 pm -
1 stop5h 24m
Sat 10/319:06 am -
1 stop5h 08m
Deal found 9/16![United Airlines logo]()
$332
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:40 am -
1 stop3h 34m
Sun 11/16:00 am -
1 stop3h 01m
Deal found 9/18![Delta logo]()
$336
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:05 am -
1 stop3h 25m
Sun 11/2210:10 am -
2 stops9h 00m
Deal found 9/16![Southwest logo]()
$346
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:45 am -
1 stop3h 31m
Sun 10/116:20 pm -
1 stop3h 31m
Deal found 9/14![Delta logo]()
$348
Best flights from Greenville to Panama CityDiscover carefully curated flight deals from Greenville to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
Discover carefully curated flight deals from Greenville to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:19 pm -
1 stop5h 05m
Sun 11/156:55 pm -
1 stop3h 58m
Deal found 9/16![Delta logo]()
$328
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:12 pm -
1 stop5h 24m
Sat 10/319:06 am -
1 stop5h 08m
Deal found 9/16![United Airlines logo]()
$332
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1711:20 am -
2 stops10h 15m
Sun 11/2210:10 am -
2 stops9h 00m
Deal found 9/16![Southwest logo]()
$351
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:05 am -
1 stop3h 25m
Sun 11/227:05 am -
1 stop3h 02m
Deal found 9/16![Delta logo]()
$334
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:45 am -
1 stop3h 31m
Sun 10/116:20 pm -
1 stop3h 31m
Deal found 9/14![Delta logo]()
$348
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:20 am -
2 stops9h 30m
Wed 10/78:05 am -
2 stops11h 00m
Deal found 9/19![Southwest logo]()
$421
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/153:42 pm -
1 stop4h 54m
Mon 1/187:05 pm -
1 stop3h 32m
Deal found 9/18![Delta logo]()
$377
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:45 am -
2 stops11h 50m
Sat 11/77:50 am -
1 stop3h 25m
Deal found 9/17![Southwest logo]()
$426
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop3h 18m
Wed 10/75:34 pm -
1 stop4h 17m
Deal found 9/19![Delta logo]()
$379
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:25 am -
2 stops12h 00m
Tue 10/610:05 am -
2 stops10h 00m
Deal found 9/16![Southwest logo]()
$456
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:40 am -
1 stop3h 34m
Sat 10/106:00 am -
1 stop3h 01m
Deal found 9/18![Delta logo]()
$429
Last-minute flights from Greenville to Panama CityDiscover last-minute flight deals from Greenville to Panama City. Data last updated September 19, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to Panama City. Data last updated September 19, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:25 am -
2 stops12h 00m
Tue 10/67:40 am -
1 stop4h 00m
Deal found 9/16![Southwest logo]()
$355
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop3h 18m
Wed 10/75:34 pm -
1 stop4h 17m
Deal found 9/16![Delta logo]()
$379
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:45 am -
1 stop3h 31m
Sun 10/116:20 pm -
1 stop3h 31m
Deal found 9/14![Delta logo]()
$348
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:33 pm -
1 stop4h 20m
Sat 10/106:42 pm -
1 stop3h 39m
Deal found 9/15![American Airlines logo]()
$245
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:40 am -
1 stop3h 34m
Sun 10/114:30 pm -
1 stop5h 21m
Deal found 9/16![Delta logo]()
$331
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:12 pm -
1 stop5h 24m
Sat 10/319:06 am -
1 stop5h 08m
Deal found 9/16![United Airlines logo]()
$332
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:40 am -
1 stop3h 34m
Sun 11/16:00 am -
1 stop3h 01m
Deal found 9/18![Delta logo]()
$336
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:40 am -
1 stop3h 34m
Mon 11/26:00 am -
1 stop3h 01m
Deal found 9/17![Delta logo]()
$301
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:25 am -
2 stops8h 00m
Mon 11/25:55 pm -
1 stop4h 00m
Deal found 9/17![Southwest logo]()
$376
One-way flights from Greenville to Panama CitySearch for one-way flight options from Greenville to Panama City. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
Search for one-way flight options from Greenville to Panama City. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:36 pm -
1 stop4h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$190
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:20 am -
2 stops9h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Southwest logo]()
$195
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:15 am -
2 stops8h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Southwest logo]()
$303
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:28 pm -
1 stop4h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![American Airlines logo]()
$330
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:25 pm -
1 stop6h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Delta logo]()
$334
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:05 pm -
2 stops9h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$339
Find flight deals from Greenville to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $245 (American Airlines) |
One-way from | $190 (American Airlines) |
Popular in | November |
Cheapest in | January |
Average price | $370 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
Use the filters below to find and compare flights from Greenville to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
GreenvillePanama City
GSP Greenville - ECP Panama City NW Florida Beaches
GSPECP
Greenville
Sat 10/3
1:36 pm-5:32 pm
1 stop4h 56m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$190
GreenvillePanama City
GSP Greenville - ECP Panama City NW Florida Beaches
GSPECP
Greenville
Sat 10/3
11:20 am-7:50 pm
2 stops9h 30m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$195
GreenvillePanama City
GSP Greenville - ECP Panama City NW Florida Beaches
GSPECP
Greenville
Sun 10/4
6:15 am-2:05 pm
2 stops8h 50m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$303
GreenvillePanama City
GSP Greenville - ECP Panama City NW Florida Beaches
GSPECP
Greenville
Thu 11/12
7:19 pm-11:24 pm
1 stop5h 05m
Panama City NW Florida Beaches
Sun 11/15
6:55 pm-11:53 pm
1 stop3h 58m
$328
GreenvillePanama City
GSP Greenville - ECP Panama City NW Florida Beaches
GSPECP
Greenville
Tue 10/27
5:12 pm-9:36 pm
1 stop5h 24m
Panama City NW Florida Beaches
Sat 10/31
9:06 am-3:14 pm
1 stop5h 08m
$332
GreenvillePanama City
GSP Greenville - ECP Panama City NW Florida Beaches
GSPECP
Greenville
Fri 9/25
6:25 pm-11:25 pm
1 stop6h 00m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$334
GreenvillePanama City
GSP Greenville - ECP Panama City NW Florida Beaches
GSPECP
Greenville
Wed 9/30
6:32 am-11:32 am
1 stop6h 00m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$334
GreenvillePanama City
GSP Greenville - ECP Panama City NW Florida Beaches
GSPECP
Greenville
Tue 11/17
8:05 am-10:30 am
1 stop3h 25m
Panama City NW Florida Beaches
Sun 11/22
7:05 am-11:07 am
1 stop3h 02m
$334
GreenvillePanama City
GSP Greenville - ECP Panama City NW Florida Beaches
GSPECP
Greenville
Fri 9/25
1:05 pm-9:05 pm
2 stops9h 00m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$339
GreenvillePanama City
GSP Greenville - ECP Panama City NW Florida Beaches
GSPECP
Greenville
Wed 9/30
7:00 am-5:00 pm
2 stops11h 00m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$339
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Greenville to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Greenville with our price prediction graph.
GSP-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to Panama City
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 19, 2026.
Peruse reviews from past customers who have flown with Delta from Greenville to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Greenville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Find flights from Greenville to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Greenville and Panama City flights
Browse other Greenville and Panama City flight options. Last updated on September 19, 2026.
Other flights from Greenville
Browse through other flights departing from Greenville. Flights are based on user searches made on Cheapflights and were last updated on September 19, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Greenville to Panama City
Discover the top airline that operate flights from Greenville to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$272 | Average$395 | FlexibilityNo cancel fee | On-timeN/A |