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$154+ Cheap flights from Panama City, FL to Greenville (ECP - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/23. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — GSP
May 26 — Jun 21
Mon 5/26
Mon 6/2
1 adult, Economy
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Cheap flight deals from Panama City to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 21, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$255
(Delta)

One-way from

$154
(Delta)

Popular in

April

Cheapest in

June

Average price

$382
Provider with most accurate pricing for Panama City NW Florida Beaches-Greenville flight deals.
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Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Greenville flights.
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From Panama City NW Florida Beaches to Greenville
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One-way flight from Panama City NW Florida Beaches to Greenville
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Highest demand for flights based on searches. 21% potential increase in price ($121 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($34 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Panama City to Greenville

Cheapest flights from Panama City to Greenville
Explore the most affordable flight options available from Panama City to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 21, 2025.

This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/127:00 amECP - GSP
1 stop5h 14mDelta
Tue 8/195:25 amGSP - ECP
1 stop3h 54mDelta
Deal found 5/20$255
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/137:00 amECP - GSP
1 stop6h 40mSouthwest
Mon 8/187:40 amGSP - ECP
2 stops10h 15mSouthwest
Deal found 5/20$306
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/135:02 pmECP - GSP
3 stops18h 02mUnited Airlines
Mon 8/187:45 pmGSP - ECP
2 stops18h 20mUnited Airlines
Deal found 5/20$593
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2112:25 pmECP - GSP
2 stops9h 53mAmerican Airlines
Thu 5/226:26 amGSP - ECP
1 stop6h 29mAmerican Airlines
Deal found 5/20$672

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 21, 2025.
Use the filters below to find and compare flights from Panama City to Greenville that are best for you.

Fly from

Panama City

Fly to

Greenville

Route

Depart

Return

Price

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Tue 8/12

7:00 am-1:14 pm

1 stop5h 14m

Greenville

Tue 8/19

5:25 am-8:19 am

1 stop3h 54m

$255

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Wed 8/13

7:00 am-2:40 pm

1 stop6h 40m

Greenville

Mon 8/18

7:40 am-4:55 pm

2 stops10h 15m

$306

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Wed 8/13

5:02 pm-12:04 pm

3 stops18h 02m

Greenville

Mon 8/18

7:45 pm-1:05 pm

2 stops18h 20m

$593

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Mon 6/23

7:25 am-2:14 pm

1 stop5h 49m

$154

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Mon 6/23

10:00 am-10:00 pm

2 stops11h 00m

$204

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/21

Compare providers for flights from Panama City to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Greenville in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Greenville

What is the cheapest month to book a flight from Panama City, Florida to Greenville?

Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Greenville (average of $329). Flying from Panama City, Florida to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to GSP?

Find hourly flight availability from Panama City to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 21, 2025.

When flying from Panama City, Florida to Greenville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 39% versus a flight in the morning.

Rainfall in Greenville by month

Plan your trip to Greenville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Greenville ranges from 3.6 - 5.1 inches per month. March is typically the wettest month, when rainfall can reach 5.1 in. November is typically the driest time to visit Greenville when rainfall is around 3.6 in.

Temperature in Greenville by month

Plan your trip to Greenville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Greenville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated May 21, 2025.
Southwest
8.0
Very good
4,289 reviews

Overall

8.0

Food

7.1

Boarding

8.2

Crew

8.6

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,289 reviews
Southwest
8.0
Very good
4,289 reviews

Overall

8.0

Food

7.1

Boarding

8.2

Crew

8.6

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,951 reviews
Southwest
8.0
Very good
4,289 reviews

Overall

8.0

Food

7.1

Boarding

8.2

Crew

8.6

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,745 reviews
Southwest
8.0
Very good
4,289 reviews

Overall

8.0

Food

7.1

Boarding

8.2

Crew

8.6

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Panama City to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City, Florida to Greenville round-trip?

    Currently priced at $255, Delta will fly you from Panama City, Florida to Greenville and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Southwest and United Airlines - these airlines can fly you to your destination from $306 and $593, respectively. You may be able to fly from Panama City, Florida to Greenville for 42% less than the average price by searching for these airlines.

  • Can I find deals for flights from Panama City to Greenville that include hotel bookings?

    Yes. In addition to deals on Panama City to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Greenville.

  • Can I find deals for business class flights from Panama City to Greenville?

    Yes. Cheapflights offers flight deals from Panama City to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Greenville (average of $329). Flying from Panama City, Florida to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Simpsonville
Duncan
Anderson
Seneca

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Top 2 airlines flying from Panama City to Greenville

Discover the top 2 airlines that operate flights from Panama City to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$242Average$486FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$256Average$476FlexibilityNo cancel feeOn-time71%

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