HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$152+ Cheap flights from Indianapolis to Panama City, FL (IND - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/14. Fares are subject to change and may not be available on all flights or dates of travel.
IND — ECP
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Indianapolis to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Indianapolis to Panama City NW Florida Beaches are usually found in August or November, booked 58 days in advance, depart on a Tuesday or Wednesday and return on a Tuesday

Cheap flight deals from Indianapolis to Panama City

Cheapest flights from Indianapolis to Panama City
Explore the most affordable flight options available from Indianapolis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:20 pmIND - ECP
1 stop6h 42mDelta
Sun 1/47:02 pmECP - IND
1 stop4h 10mDelta
Deal found 12/16$558
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/171:05 pmIND - ECP
1 stop4h 42mAmerican Airlines
Thu 1/17:15 amECP - IND
2 stops7h 17mAmerican Airlines
Deal found 12/15$565
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1710:09 amIND - ECP
1 stop3h 38mDelta
Thu 1/18:02 amECP - IND
1 stop4h 09mDelta
Deal found 12/15$576
This Southwest deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2010:20 amIND - ECP
1 stop7h 30mSouthwest
Tue 12/235:55 pmECP - IND
1 stop5h 00mSouthwest
Deal found 12/15$578
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:26 amIND - ECP
1 stop7h 55mAmerican Airlines
Wed 12/171:23 pmECP - IND
1 stop4h 51mAmerican Airlines
Deal found 12/16$587
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:11 pmIND - ECP
1 stop4h 42mAmerican Airlines
Mon 1/54:09 pmECP - IND
1 stop7h 11mAmerican Airlines
Deal found 12/15$589
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:42 pmIND - ECP
1 stop5h 15mDelta
Mon 12/228:02 amECP - IND
1 stop4h 29mDelta
Deal found 12/17$593
This Southwest deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1611:05 amIND - ECP
2 stops9h 00mSouthwest
Wed 12/173:15 pmECP - IND
1 stop5h 45mSouthwest
Deal found 12/16$598

Find flight deals from Indianapolis to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Indianapolis (IND) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$313
(Delta)

One-way from

$152
(Delta)

Popular in

April

Cheapest in

August

Average price

$443
Provider with most accurate pricing for Indianapolis-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Panama City NW Florida Beaches flights.
Search Deals
From Indianapolis to Panama City NW Florida Beaches
Search Deals
One-way flight from Indianapolis to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($57 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama City that are best for you.

Fly from

Indianapolis

Fly to

Panama City

Route

Depart

Return

Price

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Sun 3/1

5:08 pm-9:56 pm

1 stop5h 48m

Panama City NW Florida Beaches

Tue 3/10

2:10 pm-8:05 pm

1 stop4h 55m

$336

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Wed 3/4

8:05 am-2:55 pm

1 stop7h 50m

Panama City NW Florida Beaches

Sun 3/8

6:40 am-11:50 am

1 stop4h 10m

$341

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Sun 3/1

10:23 am-3:57 pm

1 stop6h 34m

Panama City NW Florida Beaches

Tue 3/10

8:20 am-4:57 pm

2 stops7h 37m

$346

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Tue 2/10

7:01 am-5:33 pm

2 stops11h 32m

Panama City NW Florida Beaches

Sun 2/15

1:15 pm-9:00 pm

1 stop6h 45m

$346

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Sun 2/1

6:55 pm-10:40 pm

1 stop4h 45m

Panama City NW Florida Beaches

Sat 2/7

1:10 pm-5:23 pm

1 stop3h 13m

$351

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Tue 2/3

9:00 am-4:13 pm

1 stop8h 13m

Panama City NW Florida Beaches

Wed 2/4

1:10 pm-8:07 pm

1 stop5h 57m

$373

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Tue 1/27

9:00 am-4:12 pm

1 stop8h 12m

Panama City NW Florida Beaches

Wed 1/28

6:30 am-3:52 pm

1 stop8h 22m

$373

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Thu 5/28

4:15 pm-7:36 pm

1 stop4h 21m

Panama City NW Florida Beaches

Sun 5/31

6:00 am-10:31 am

1 stop3h 31m

$379

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Sun 1/25

9:00 am-4:12 pm

1 stop8h 12m

Panama City NW Florida Beaches

Fri 1/30

1:10 pm-8:07 pm

1 stop5h 57m

$379

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Tue 1/13

11:11 am-3:46 pm

1 stop5h 35m

$152

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 17 results
1
2

Compare providers for flights from Indianapolis to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to Panama City in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Indianapolis-Panama City, Florida flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Indianapolis-Panama City, Florida flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Indianapolis-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Indianapolis-Panama City, Florida flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Indianapolis to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Panama City

How far ahead should I book a flight from Indianapolis to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from Indianapolis to Panama City. Price data was last updated on December 12, 2025.

The best time to book flights from Indianapolis to Panama City, Florida is 58 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Indianapolis to Panama City, Florida?

Currently, April is the cheapest month in which you can book a flight from Indianapolis to Panama City, Florida (average of $52). Flying from Indianapolis to Panama City, Florida in December is currently the most expensive (average of $117). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to ECP?

Find hourly flight availability from Indianapolis to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 18% on flights from Indianapolis to Panama City, Florida by exploring options for tickets in the evening.

What is the cheapest day to fly from Indianapolis to Panama City, Florida?

Use this chart to determine the cheapest time to fly round-trip from Indianapolis to Panama City. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Indianapolis to Panama City, Florida flight should consider departing on Wednesday evenings when fares are most often at their lowest. Thursday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated December 18, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Indianapolis to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,250 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,250 reviews
Southwest
7.9
Good
4,250 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,005 reviews
Southwest
7.9
Good
4,250 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,091 reviews
Southwest
7.9
Good
4,250 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,054 reviews
Southwest
7.9
Good
4,250 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Indianapolis to Panama City, Florida flight route?

    The Indianapolis to Panama City NW Florida Beaches flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Indianapolis to Panama City, Florida?

    A quick flight from Indianapolis to Panama City, Florida can take about 5h 48m. United Airlines provides one of the quickest options available for as low as $336. There are 647 mi between Indianapolis and Panama City, Florida. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Indianapolis to Panama City, Florida round-trip?

    Delta, at $226, was found to be the cheapest airline from Indianapolis to Panama City, Florida.Alternate airlines to your destination round-trip include American Airlines and United Airlines. You may be able to fly from Indianapolis to Panama City, Florida for 42% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Indianapolis to Panama City, Florida one-way?

    $117 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and Southwest, with prices starting from $127 and $179, respectively.

  • Can I find deals for flights from Indianapolis to Panama City that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Panama City.

  • Can I find deals for business class flights from Indianapolis to Panama City?

    Yes. Cheapflights offers flight deals from Indianapolis to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Panama City, Florida?

    Currently, April is the cheapest month in which you can book a flight from Indianapolis to Panama City, Florida (average of $52). Flying from Indianapolis to Panama City, Florida in December is currently the most expensive (average of $117). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Indianapolis to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Fort Lauderdale flights
O'Hare Intl to Orlando flights
O'Hare Intl to Miami flights
O'Hare Intl to Tampa flights
Cincinnati to Orlando flights
Midway to Orlando flights
Midway to Fort Lauderdale flights
Cincinnati to Fort Lauderdale flights
O'Hare Intl to Fort Myers flights
Midway to Miami flights
Indianapolis to Orlando flights
Midway to Tampa flights
O'Hare Intl to West Palm Beach flights
O'Hare Intl to Sarasota flights
O'Hare Intl to Key West flights
Midway to Fort Myers flights
Cincinnati to Fort Myers flights
Indianapolis to Fort Lauderdale flights
Cincinnati to Tampa flights
Indianapolis to Miami flights
Cincinnati to Miami flights
O'Hare Intl to Jacksonville flights
O'Hare Intl to Pensacola flights
Indianapolis to Tampa flights
Louisville to Miami flights
Indianapolis to Fort Myers flights
O'Hare Intl to Panama City flights
Louisville to Fort Lauderdale flights
Midway to West Palm Beach flights
Dayton to Orlando flights
Cincinnati to Orlando Sanford Intl flights
Louisville to Orlando flights
Midway to Key West flights
Louisville to Tampa flights
Indianapolis to Orlando Sanford Intl flights
Dayton to Tampa flights
Indianapolis to West Palm Beach flights
Cincinnati to Sarasota flights
Louisville to Fort Myers flights
Midway to Jacksonville flights
Cincinnati to St Petersburg flights
Rockford to Orlando Sanford Intl flights
Midway to Pensacola flights
Dayton to Fort Myers flights
Cincinnati to West Palm Beach flights
Dayton to Sarasota flights
Dayton to Fort Lauderdale flights
Fort Wayne to Orlando flights
Indianapolis to Sarasota flights
Midway to Panama City flights

Top 4 airlines flying from Indianapolis to Panama City

Discover the top 4 airlines that operate flights from Indianapolis to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$233Average$369FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$377FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$253Average$378FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$307Average$442FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.