HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$108+ Cheap flights from Indianapolis to Panama City, FL (IND - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel.
IND — ECP
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Indianapolis to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Indianapolis to Panama City NW Florida Beaches are usually found in January or August, booked 58 days in advance, depart on a Tuesday or Wednesday and return on a Tuesday

Cheap flight deals from Indianapolis to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Indianapolis (IND) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$215
(Delta)

One-way from

$108
(Delta)

Popular in

March

Cheapest in

January

Average price

$355
From Indianapolis to Panama City NW Florida Beaches
Search Deals
One-way flight from Indianapolis to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($62 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Indianapolis to Panama City

Cheapest flights from Indianapolis to Panama City
Explore the most affordable flight options available from Indianapolis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:10 amIND - ECP
1 stop8h 29mDelta
Wed 10/86:00 amECP - IND
1 stop6h 06mDelta
Deal found 9/12$215
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/147:00 amIND - ECP
1 stop8h 30mDelta
Wed 10/155:32 pmECP - IND
1 stop5h 50mDelta
Deal found 9/15$267
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/147:00 amIND - ECP
1 stop8h 30mDelta
Thu 10/166:17 pmECP - IND
1 stop5h 05mDelta
Deal found 9/15$281
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/147:00 amIND - ECP
1 stop8h 30mDelta
Fri 10/173:33 pmECP - IND
1 stop6h 27mDelta
Deal found 9/15$288
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/252:25 pmIND - ECP
2 stops8h 23mUnited Airlines
Wed 10/296:30 amECP - IND
1 stop7h 59mUnited Airlines
Deal found 9/14$291
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/411:27 amIND - ECP
2 stops11h 21mUnited Airlines
Wed 10/85:08 pmECP - IND
1 stop5h 22mUnited Airlines
Deal found 9/13$293
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/247:15 amIND - ECP
1 stop6h 55mUnited Airlines
Wed 10/296:30 amECP - IND
2 stops8h 13mUnited Airlines
Deal found 9/14$298
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:00 amIND - ECP
1 stop7h 00mDelta
Mon 11/171:45 pmECP - IND
1 stop8h 15mDelta
Deal found 9/14$302
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/242:00 pmIND - ECP
2 stops9h 35mSouthwest
Wed 10/291:45 pmECP - IND
1 stop7h 10mSouthwest
Deal found 9/15$303
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/711:18 amIND - ECP
1 stop6h 57mAmerican Airlines
Mon 11/105:55 pmECP - IND
1 stop4h 31mAmerican Airlines
Deal found 9/13$307

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama City that are best for you.

Fly from

Indianapolis

Fly to

Panama City

Route

Depart

Return

Price

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Sat 10/25

6:51 pm-10:41 pm

1 stop4h 50m

Panama City NW Florida Beaches

Wed 10/29

5:00 pm-9:43 pm

1 stop3h 43m

$281

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Tue 10/14

7:00 am-2:30 pm

1 stop8h 30m

Panama City NW Florida Beaches

Fri 10/17

3:33 pm-11:00 pm

1 stop6h 27m

$288

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Sat 10/25

2:25 pm-9:48 pm

2 stops8h 23m

Panama City NW Florida Beaches

Wed 10/29

6:30 am-3:29 pm

1 stop7h 59m

$291

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Sat 10/4

11:27 am-9:48 pm

2 stops11h 21m

Panama City NW Florida Beaches

Wed 10/8

5:08 pm-11:30 pm

1 stop5h 22m

$293

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Fri 10/24

7:15 am-1:10 pm

1 stop6h 55m

Panama City NW Florida Beaches

Wed 10/29

6:30 am-3:43 pm

2 stops8h 13m

$298

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Fri 11/14

6:00 am-10:26 am

1 stop5h 26m

Panama City NW Florida Beaches

Mon 11/17

1:45 pm-11:00 pm

1 stop8h 15m

$302

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Fri 11/14

5:22 pm-9:49 pm

1 stop5h 27m

Panama City NW Florida Beaches

Mon 11/17

5:00 pm-11:44 pm

1 stop5h 44m

$302

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Sun 11/2

7:00 am-2:30 pm

1 stop8h 30m

Panama City NW Florida Beaches

Wed 11/5

3:33 pm-11:00 pm

1 stop6h 27m

$323

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Wed 10/8

7:00 am-2:30 pm

1 stop8h 30m

Panama City NW Florida Beaches

Wed 10/15

3:33 pm-11:00 pm

1 stop6h 27m

$323

IndianapolisPanama City

IND - ECP

INDECP

Indianapolis

Sat 10/4

7:10 am-11:38 am

1 stop5h 28m

Panama City NW Florida Beaches

Wed 10/8

6:00 am-10:33 am

1 stop3h 33m

$328

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/12

Showing 1-10 of 19 results
1
2

Best time to book a flight from Indianapolis to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Panama City

How far ahead should I book a flight from Indianapolis to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from Indianapolis to Panama City. Price data was last updated on September 12, 2025.

The best time to book flights from Indianapolis to Panama City, Florida is 58 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Indianapolis to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Indianapolis to Panama City, Florida (average of $346). Flying from Indianapolis to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to ECP?

Find hourly flight availability from Indianapolis to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 20% on flights from Indianapolis to Panama City, Florida by exploring options for tickets in the evening.

What is the cheapest day to fly from Indianapolis to Panama City, Florida?

Use this chart to determine the cheapest time to fly round-trip from Indianapolis to Panama City. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Indianapolis to Panama City, Florida flight should consider departing on Tuesday at noon when fares are most often at their lowest. Thursday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 15, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Indianapolis to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,954 reviews
Southwest
8.0
Very good
4,242 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,929 reviews
Southwest
8.0
Very good
4,242 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Indianapolis to Panama City, Florida flight route?

    The Indianapolis to Panama City NW Florida Beaches flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Indianapolis to Panama City, Florida?

    A quick flight from Indianapolis to Panama City, Florida can take about 4h 50m. Delta provides one of the quickest options available for as low as $281. There are 647 mi between Indianapolis and Panama City, Florida. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Indianapolis to Panama City, Florida round-trip?

    Delta, at $244, was found to be the cheapest airline from Indianapolis to Panama City, Florida.Alternate airlines to your destination round-trip include American Airlines and United Airlines. You may be able to fly from Indianapolis to Panama City, Florida for 36% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Indianapolis to Panama City, Florida one-way?

    $113 is the cheapest one-way deal found within the past few days, from Southwest. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $134 and $134, respectively.

  • Where are the most common layover locations when flying from Indianapolis to Panama City, Florida?

    Most of the time, Indianapolis to Panama City, Florida flights that have layovers will stop in Atlanta.

  • What are some popular things to do or see while on a layover in Atlanta?

    Georgia Aquarium, Tabernacle, and Fox Theatre are currently the most popular points of interest in Atlanta at the moment. Those on a layover in Atlanta interested in visiting Georgia Aquarium, Tabernacle, or Fox Theatre can do so by traveling 8.6 mi, 8.3 mi, and 9.3 mi, respectively from Atlanta Hartsfield-Jackson. Travelers can rent a car at Atlanta Hartsfield-Jackson for an average daily rate of $53 to make sightseeing during their layover a little easier.

  • Where are the least popular layover locations for Indianapolis to Panama City, Florida flights?

    Flights departing from Indianapolis and landing in Panama City, Florida layover in Charlotte least frequently.

  • Can I find deals for flights from Indianapolis to Panama City that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Panama City.

  • Can I find deals for business class flights from Indianapolis to Panama City?

    Yes. Cheapflights offers flight deals from Indianapolis to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Indianapolis to Panama City, Florida (average of $346). Flying from Indianapolis to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Indianapolis to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Orlando flights
O'Hare Intl to Fort Lauderdale flights
O'Hare Intl to Miami flights
Cincinnati to Orlando flights
O'Hare Intl to Tampa flights
O'Hare Intl to Fort Myers flights
Midway to Miami flights
Indianapolis to Orlando flights
Midway to Orlando flights
Cincinnati to Tampa flights
Midway to Fort Lauderdale flights
O'Hare Intl to Jacksonville flights
Cincinnati to Fort Lauderdale flights
Indianapolis to Miami flights
O'Hare Intl to Sarasota flights
Cincinnati to Miami flights
O'Hare Intl to West Palm Beach flights
Midway to Tampa flights
Indianapolis to Fort Lauderdale flights
O'Hare Intl to Key West flights
Midway to Fort Myers flights
Cincinnati to Fort Myers flights
O'Hare Intl to Pensacola flights
Indianapolis to Tampa flights
Louisville to Orlando flights
Louisville to Miami flights
Cincinnati to Orlando Sanford Intl flights
Indianapolis to Orlando Sanford Intl flights
Midway to Jacksonville flights
Indianapolis to Fort Myers flights
O'Hare Intl to Panama City flights
Louisville to Tampa flights
Dayton to Orlando flights
Louisville to Fort Lauderdale flights
Midway to West Palm Beach flights
Dayton to Tampa flights
Cincinnati to St Petersburg flights
Midway to Sarasota flights
Fort Wayne to Orlando flights
Cincinnati to Key West flights
Dayton to Miami flights
Midway to Key West flights
Cincinnati to Sarasota flights
Indianapolis to St Petersburg flights
Dayton to Fort Lauderdale flights
Indianapolis to West Palm Beach flights
Indianapolis to Sarasota flights
Cincinnati to Pensacola flights
Indianapolis to Key West flights
Midway to Pensacola flights

Top 4 airlines flying from Indianapolis to Panama City

Discover the top 4 airlines that operate flights from Indianapolis to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$244Average$367FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$442FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$376FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$307Average$443FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.