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$87+ Cheap flights from Panama City, FL to Indianapolis (ECP - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/3. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — IND
janv. 3 — janv. 101
sam. 1/3
sam. 1/10
1 adult, Economy
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Cheap flight deals from Panama City to Indianapolis

Cheapest flights from Panama City to Indianapolis
Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on décembre 4, 2025.

This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 12/2611:11 amECP - IND
1 stop4h 25mAmerican Airlines
mar. 1/611:30 amIND - ECP
1 stop7h 03mAmerican Airlines
Deal found 12/4$294
This Delta deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 12/286:00 amECP - IND
1 stop6h 31mDelta
mar. 1/66:00 amIND - ECP
1 stop4h 12mDelta
Deal found 12/4$296
This United Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 12/282:55 pmECP - IND
1 stop7h 49mUnited Airlines
jeu. 1/85:05 pmIND - ECP
1 stop5h 54mUnited Airlines
Deal found 12/4$318
This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 12/2811:11 amECP - IND
2 stops10h 18mAmerican Airlines
mar. 1/69:08 amIND - ECP
2 stops9h 25mAmerican Airlines
Deal found 12/4$324
This Southwest deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 12/287:30 amECP - IND
2 stops8h 30mSouthwest
mar. 1/68:05 amIND - ECP
1 stop7h 50mSouthwest
Deal found 12/4$348
This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 12/2811:11 amECP - IND
2 stops10h 18mAmerican Airlines
jeu. 1/87:01 amIND - ECP
2 stops11h 32mAmerican Airlines
Deal found 12/4$359
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 12/175:00 pmECP - IND
1 stop6h 26mDelta
dim. 12/217:38 pmIND - ECP
1 stop4h 06mDelta
Deal found 12/2$383
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 12/178:30 amECP - IND
2 stops11h 30mAmerican Airlines
dim. 12/218:11 pmIND - ECP
1 stop4h 42mAmerican Airlines
Deal found 12/2$388
This Delta deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 12/256:00 amECP - IND
1 stop6h 11mDelta
mar. 12/305:20 pmIND - ECP
1 stop3h 36mDelta
Deal found 12/3$415

Find flight deals from Panama City to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated décembre 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$197
(American Airlines)

One-way from

$87
(American Airlines)

Popular in

March

Cheapest in

September

Average price

$337
Provider with most accurate pricing for Panama City NW Florida Beaches-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Indianapolis flights.
Search Deals
From Panama City NW Florida Beaches to Indianapolis
Search Deals
One-way flight from Panama City NW Florida Beaches to Indianapolis
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($98 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated décembre 4, 2025.
Use the filters below to find and compare flights from Panama City to Indianapolis that are best for you.

Fly from

Panama City

Fly to

Indianapolis

Route

Depart

Return

Price

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

sam. 2/14

1:06 pm-9:43 pm

1 stop7h 37m

Indianapolis

mer. 2/18

6:00 am-12:47 pm

1 stop7h 47m

$197

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

mar. 1/13

10:01 am-3:14 pm

1 stop4h 13m

Indianapolis

jeu. 1/15

6:00 am-9:12 am

1 stop4h 12m

$199

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

sam. 2/14

6:00 am-12:37 pm

1 stop5h 37m

Indianapolis

mer. 2/18

6:00 am-8:41 am

1 stop3h 41m

$199

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

sam. 1/10

6:00 am-11:14 am

1 stop4h 14m

Indianapolis

lun. 1/12

4:20 pm-7:50 pm

1 stop4h 30m

$221

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

jeu. 1/15

6:03 pm-11:27 pm

1 stop4h 24m

Indianapolis

lun. 1/19

6:00 am-11:33 am

1 stop6h 33m

$268

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

sam. 12/27

4:09 pm-12:38 am

1 stop7h 29m

Indianapolis

mar. 1/6

11:30 am-5:33 pm

1 stop7h 03m

$294

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

ven. 12/26

11:11 am-10:29 pm

2 stops10h 18m

Indianapolis

mar. 1/6

10:53 am-5:33 pm

2 stops7h 40m

$304

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

dim. 12/28

2:55 pm-11:44 pm

1 stop7h 49m

Indianapolis

jeu. 1/8

5:05 pm-9:59 pm

1 stop5h 54m

$318

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

mar. 1/13

12:03 pm-10:28 pm

2 stops9h 25m

Indianapolis

jeu. 1/15

9:08 am-5:33 pm

2 stops9h 25m

$323

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

mar. 2/3

3:27 pm-10:54 pm

1 stop6h 27m

$87

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/4

Showing 1-10 of 15 results
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Compare providers for flights from Panama City to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Indianapolis in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Indianapolis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City, Florida-Indianapolis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Indianapolis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Indianapolis

What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?

Currently, June is the cheapest month in which you can book a flight from Panama City, Florida to Indianapolis (average of $60). Flying from Panama City, Florida to Indianapolis in December is currently the most expensive (average of $137). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to IND?

Find hourly flight availability from Panama City to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated décembre 4, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama City, Florida to Indianapolis in the evening. If you’re flexible enough to do this you can expect to save up to 36% on your trip compared to booking a flight in the afternoon.

How much does it cost to fly round-trip from Panama City, Florida to Indianapolis?

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated décembre 4, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Panama City to Indianapolis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,250 reviews

Crew

8.6

Food

7.0

Comfort

8.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,250 reviews
Southwest
8.0
Very good
4,250 reviews

Crew

8.6

Food

7.0

Comfort

8.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,011 reviews
Southwest
8.0
Very good
4,250 reviews

Crew

8.6

Food

7.0

Comfort

8.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,047 reviews
Southwest
8.0
Very good
4,250 reviews

Crew

8.6

Food

7.0

Comfort

8.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Panama City to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Indianapolis?

    A quick flight from Panama City, Florida to Indianapolis can take about 4h 13m. American Airlines provides one of the quickest options available for as low as $199. There are 647 mi between Panama City, Florida and Indianapolis. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Panama City, Florida to Indianapolis round-trip?

    Cheapflights users have booked flights from Panama City, Florida to Indianapolis round-trip from $226. Other airlines that can offer you cheap pricing are American Airlines, from $286, and Southwest, from $333. Delta is currently priced 42% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Panama City, Florida to Indianapolis one-way?

    $113 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on United Airlines and Delta, with prices starting from $127 and $127, respectively.

  • Can I find deals for flights from Panama City to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Panama City to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Indianapolis.

  • Can I find deals for business class flights from Panama City to Indianapolis?

    Yes. Cheapflights offers flight deals from Panama City to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?

    Currently, June is the cheapest month in which you can book a flight from Panama City, Florida to Indianapolis (average of $60). Flying from Panama City, Florida to Indianapolis in December is currently the most expensive (average of $137). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Noblesville
Fishers
Greenwood
Anderson
Kokomo
Plainfield
Franklin
Carmel
Crawfordsville
Bloomington
Speedway

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Alternative routes for Panama City to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Panama City to Indianapolis

Discover the top 3 airlines that operate flights from Panama City to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated décembre 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$226Average$358FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$286Average$406FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$333Average$409FlexibilityNo cancel feeOn-time63%

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