What are the cheapest airlines flying from Panama City, Florida to Indianapolis round-trip?

Cheapflights users have booked flights from Panama City, Florida to Indianapolis round-trip from $227. Other airlines that can offer you cheap pricing are Delta, from $244, and Southwest, from $379. American Airlines is currently priced 40% below the average price you’ll pay for this route.

What are the cheapest airlines to fly from Panama City, Florida to Indianapolis one-way?

$114 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Southwest and Delta, with prices starting from $124 and $131, respectively.

What is the cheapest day to fly from Panama City, Florida to Indianapolis?

Travelers seeking maximum savings on their Panama City, Florida to Indianapolis flight should consider departing on Monday afternoons when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Indianapolis ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indianapolis when rainfall is around 2.3 in.

If weather is an important factor for your trip to Indianapolis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

What are the cheapest flights from Panama City, Florida to Indianapolis?

On average you can expect to pay $381 for a flight from Panama City, Florida to Indianapolis. The cheapest flight overall is $339 while the most popular route, (Panama City NW Florida Beaches - Indianapolis) is currently priced at $227.

What are the most popular airlines that fly from Panama City, Florida to Indianapolis?

American Airlines, Delta and Southwest are the most popular airlines when flying from Panama City, Florida to Indianapolis.

What is the cheapest day to fly round-trip from Panama City, Florida to Indianapolis?

Users have found that leaving on a Monday can be a cost-effective option. It’s possible to save up to 123% on your flight compared to booking on days when demand is much higher.

What is the cheapest month to fly from Panama City, Florida to Indianapolis?

Due to multiple factors, expect to potentially pay more when booking in March. For low rates, July can be a great choice for travel to Indianapolis. Flights to Indianapolis from Panama City, Florida in July are about $383 on average during July, but can be found for as low as $180.

Can I find deals for flights from Panama City to Indianapolis that include hotel bookings?

Yes. In addition to deals on Panama City to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to Indianapolis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Indianapolis.

Can I find deals for business class flights from Panama City to Indianapolis?

Yes. Cheapflights offers flight deals from Panama City to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$114+ Flights from Panama City, FL to Indianapolis

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1. Tell us where you want to go

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2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheapflights Tip: The best prices from Panama City NW Florida Beaches to Indianapolis are usually found in July or January, booked 31 days in advance, depart on a Tuesday or Wednesday and return on a Tuesday

Cheap flight deals from Panama City to Indianapolis

Round-trip from	$227 (American Airlines)
One-way from	$114 (United Airlines)
Popular in	March
Cheapest in	July
Average price	$292
Good round-trip deal	$377 or less

From Panama City NW Florida Beaches to Indianapolis

Search Deals

One-way flight from Panama City NW Florida Beaches to Indianapolis

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Highest demand for flights based on searches. 22% potential increase in price ($114 potential increase over avg. RT price).

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Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Price to beat on a round-trip flight from Panama City NW Florida Beaches to Indianapolis.

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Find flight deals from Panama City to Indianapolis

Cheapest flights from Panama City to Indianapolis
Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

Wed 10/81:55 pmECP - IND

1 stop7h 01mUnited Airlines

Tue 10/145:24 pmIND - ECP

1 stop5h 24mUnited Airlines

Deal found 7/1

$227

Wed 10/86:44 amECP - IND

2 stops7h 34mAmerican Airlines

Tue 10/142:25 pmIND - ECP

1 stop6h 07mAmerican Airlines

Deal found 7/1

$232

Wed 9/36:00 amECP - IND

1 stop3h 26mDelta

Sat 9/61:55 pmIND - ECP

1 stop5h 03mDelta

Deal found 6/30

$244

Wed 10/84:05 pmECP - IND

2 stops5h 45mSouthwest

Tue 10/146:35 amIND - ECP

2 stops8h 55mSouthwest

Deal found 7/1

$308

Best flights from Panama City to Indianapolis
Discover carefully curated flight deals from Panama City to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 1, 2025.

Wed 8/206:35 amECP - IND

1 stop6h 10mAmerican Airlines

Wed 8/206:37 pmIND - ECP

1 stop4h 32mAmerican Airlines

Deal found 6/30

$227

Wed 9/36:00 amECP - IND

1 stop3h 26mDelta

Sat 9/61:55 pmIND - ECP

1 stop5h 03mDelta

Deal found 6/30

$244

Thu 8/71:30 pmECP - IND

2 stops8h 25mSouthwest

Sun 8/105:35 amIND - ECP

2 stops8h 50mSouthwest

Deal found 6/29

$379

Fri 7/255:02 pmECP - IND

1 stop5h 28mUnited Airlines

Mon 7/287:30 amIND - ECP

2 stops9h 51mUnited Airlines

Deal found 6/30

$432

Last-minute flights from Panama City to Indianapolis
Discover last-minute flight deals from Panama City to Indianapolis. Data last updated July 1, 2025 and is based on user searches.

Wed 7/92:35 pmECP - IND

1 stop6h 47mAmerican Airlines

Sun 7/136:05 amIND - ECP

1 stop5h 08mAmerican Airlines

Deal found 6/30

$452

Wed 7/97:15 amECP - IND

1 stop7h 30mSouthwest

Sun 7/1312:55 pmIND - ECP

Nonstop1h 50mSouthwest

Deal found 6/30

$503

Sun 7/207:38 pmECP - IND

1 stop4h 01mDelta

Sun 8/178:15 amIND - ECP

1 stop3h 19mDelta

Deal found 6/30

$361

Fri 7/255:02 pmECP - IND

1 stop5h 28mUnited Airlines

Mon 7/287:30 amIND - ECP

2 stops9h 51mUnited Airlines

Deal found 6/30

$432

Wed 8/206:35 amECP - IND

1 stop6h 10mAmerican Airlines

Wed 8/206:37 pmIND - ECP

1 stop4h 32mAmerican Airlines

Deal found 6/30

$227

One-way flights from Panama City to Indianapolis
Search for one-way flight options from Panama City to Indianapolis. Find affordable one-way fares based on user searches. Data last updated July 1, 2025.

Mon 9/225:06 pmECP - IND

1 stop5h 21mUnited Airlines

Deal found 6/30

$114

Thu 9/251:35 pmECP - IND

2 stops8h 20mSouthwest

Deal found 6/30

$124

Sat 9/279:13 amECP - IND

1 stop5h 22mDelta

Deal found 7/1

$131

Sat 8/235:30 amECP - IND

2 stops9h 00mAmerican Airlines

Deal found 6/29

$136

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 10/8

1:55 pm-9:56 pm

1 stop7h 01m

Indianapolis

Tue 10/14

5:24 pm-9:48 pm

1 stop5h 24m

$227

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 10/8

6:44 am-3:18 pm

2 stops7h 34m

Indianapolis

Tue 10/14

2:25 pm-7:32 pm

1 stop6h 07m

$232

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 9/3

6:00 am-10:26 am

1 stop3h 26m

Indianapolis

Sat 9/6

1:55 pm-5:58 pm

1 stop5h 03m

$244

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 10/8

4:05 pm-10:50 pm

2 stops5h 45m

Indianapolis

Tue 10/14

6:35 am-2:30 pm

2 stops8h 55m

$308

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Thu 9/4

5:02 pm-12:08 am

1 stop6h 06m

$114

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Tue 9/9

6:30 am-4:32 pm

2 stops9h 02m

$119

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Thu 9/4

1:35 pm-10:55 pm

2 stops8h 20m

$124

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Sat 10/25

6:31 am-1:34 pm

1 stop6h 03m

$130

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Best time to book a flight from Panama City to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Indianapolis

What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Indianapolis (average of $297). Flying from Panama City, Florida to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to IND?

A simple way to save on the total cost of your ticket is to fly from Panama City, Florida to Indianapolis in the evening. If you’re flexible enough to do this you can expect to save up to 37% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Indianapolis

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Panama City to Indianapolis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Southwest

8.0

Very good

4,275 reviews

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Delta

8.0

Very good

7,974 reviews

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

United Airlines

7.4

Good

8,858 reviews

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

What are the cheapest airlines flying from Panama City, Florida to Indianapolis round-trip?
Cheapflights users have booked flights from Panama City, Florida to Indianapolis round-trip from $227. Other airlines that can offer you cheap pricing are Delta, from $244, and Southwest, from $379. American Airlines is currently priced 40% below the average price you’ll pay for this route.
What are the cheapest airlines to fly from Panama City, Florida to Indianapolis one-way?
$114 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Southwest and Delta, with prices starting from $124 and $131, respectively.
What are the cheapest flights from Panama City, Florida to Indianapolis?
On average you can expect to pay $381 for a flight from Panama City, Florida to Indianapolis. The cheapest flight overall is $339 while the most popular route, (Panama City NW Florida Beaches - Indianapolis) is currently priced at $227.
Can I find deals for flights from Panama City to Indianapolis that include hotel bookings?
Yes. In addition to deals on Panama City to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to Indianapolis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Indianapolis.
Can I find deals for business class flights from Panama City to Indianapolis?
Yes. Cheapflights offers flight deals from Panama City to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?
Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Indianapolis (average of $297). Flying from Panama City, Florida to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Other flights to Indianapolis

Top 3 airlines flying from Panama City to Indianapolis

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$162	Average$369	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$238	Average$331	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$333	Average$402	FlexibilityNo cancel fee	On-time63%

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$114+ Cheap flights from Panama City, FL to Indianapolis (ECP - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to Indianapolis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Panama City NW Florida Beaches to Indianapolis are usually found in July or January, booked 31 days in advance, depart on a Tuesday or Wednesday and return on a Tuesday

Cheap flight deals from Panama City to Indianapolis

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Find flight deals from Panama City to Indianapolis

Cheapest flights from Panama City to IndianapolisExplore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Indianapolis that are best for you.

Best time to book a flight from Panama City to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama City with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Indianapolis

What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?

What is the cheapest time of day to fly from ECP to IND?

Find hourly flight availability from Panama City to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 1, 2025.

Reviews of airlines servicing Indianapolis

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Panama City to Indianapolis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Panama City, Florida to Indianapolis round-trip?

What are the cheapest airlines to fly from Panama City, Florida to Indianapolis one-way?

What are the cheapest flights from Panama City, Florida to Indianapolis?

Can I find deals for flights from Panama City to Indianapolis that include hotel bookings?

How can I find direct flights from Panama City to Indianapolis?

Can I find deals for business class flights from Panama City to Indianapolis?

What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?

Traveling to a place near Panama City?

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Top 3 airlines flying from Panama City to Indianapolis

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Cheapest flights from Panama City to Indianapolis
Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.