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$277+ Cheap flights from Panama City (PTY) to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — RDU
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Cheap flight deals from Panama City to North Carolina

Keep the following information in mind while searching for Panama City to North Carolina flight deals. Data was last updated October 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$424
(American Airlines)

One-way from

$277
(Avianca Connect)

Popular in

December

Cheapest in

September

Average price

$464

Good round-trip deal

$494 or less
Provider with most accurate pricing for Panama City Tocumen Intl-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Raleigh-Durham flights.
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From Panama City Tocumen Intl to North Carolina
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One-way flight from Panama City Tocumen Intl to North Carolina
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Highest demand for flights based on searches. 2% potential increase in price ($12 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to North Carolina.
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Find flight deals from Panama City to North Carolina

Cheapest flights from Panama City to North Carolina
Explore the most affordable flight options available from Panama City to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:50 pmPTY - CLT
1 stop17h 17mAmerican Airlines
Wed 12/107:58 pmCLT - PTY
1 stop19h 44mAmerican Airlines
Deal found 10/15$424
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/214:41 pmPTY - CLT
1 stop28h 55mUnited Airlines
Fri 11/286:40 amCLT - PTY
1 stop8h 05mUnited Airlines
Deal found 10/15$451
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/139:33 pmPTY - CLT
1 stop10h 14mMultiple Airlines
Tue 11/187:59 pmCLT - PTY
1 stop12h 07mMultiple Airlines
Deal found 10/15$460
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:50 pmPTY - CLT
1 stop20h 41mAmerican Airlines
Tue 1/136:55 pmCLT - PTY
1 stop18h 32mAmerican Airlines
Deal found 10/15$461
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/212:43 pmPTY - CLT
2 stops15h 52mAmerican Airlines
Fri 11/285:15 amCLT - PTY
1 stop8h 28mAmerican Airlines
Deal found 10/15$467
This Copa Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/178:57 amPTY - RDU
Nonstop4h 28mCopa Airlines
Wed 12/313:11 pmRDU - PTY
Nonstop4h 35mCopa Airlines
Deal found 10/15$495
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/173:46 pmPTY - RDU
1 stop8h 32mDelta
Wed 12/319:58 amRDU - PTY
1 stop10h 02mDelta
Deal found 10/15$501
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/214:41 pmPTY - RDU
1 stop18h 40mUnited Airlines
Wed 12/316:05 amRDU - PTY
1 stop8h 40mUnited Airlines
Deal found 10/16$510
This Copa Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/168:57 amPTY - RDU
Nonstop4h 30mCopa Airlines
Sun 11/303:14 pmRDU - PTY
Nonstop4h 32mCopa Airlines
Deal found 10/16$511
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/242:53 pmPTY - RDU
2 stops20h 02mAmerican Airlines
Mon 1/56:37 amRDU - PTY
2 stops9h 17mAmerican Airlines
Deal found 10/16$514
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/242:55 amPTY - RDU
2 stops17h 55mMultiple Airlines
Mon 12/83:21 pmRDU - PTY
1 stop16h 45mMultiple Airlines
Deal found 10/16$515
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/104:43 pmPTY - RDU
1 stop7h 16mAmerican Airlines
Wed 12/178:36 amRDU - PTY
1 stop7h 06mAmerican Airlines
Deal found 10/15$518

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Panama City to North Carolina that are best for you.

Fly from

Panama City

Fly to

North Carolina

Route

Depart

Return

Price

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Wed 12/3

2:50 pm-8:07 am

1 stop17h 17m

Charlotte Douglas

Wed 12/10

7:58 pm-3:42 pm

1 stop19h 44m

$424

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Fri 11/21

4:41 pm-9:36 pm

1 stop28h 55m

Charlotte Douglas

Fri 11/28

6:40 am-7:38 pm

1 stop12h 58m

$451

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 11/13

9:33 pm-7:47 am

1 stop10h 14m

Charlotte Douglas

Tue 11/18

7:59 pm-8:06 am

1 stop12h 07m

$460

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Fri 11/21

2:43 pm-6:35 am

2 stops15h 52m

Charlotte Douglas

Fri 11/28

5:15 am-1:43 pm

1 stop8h 28m

$460

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Wed 12/3

2:50 pm-11:31 am

1 stop20h 41m

Charlotte Douglas

Tue 1/13

6:55 pm-1:27 pm

1 stop18h 32m

$461

Panama CityRaleigh

PTY - RDU

PTYRDU

Panama City Tocumen Intl

Fri 1/16

8:57 am-1:15 pm

Nonstop4h 18m

Raleigh-Durham

Wed 1/21

3:09 pm-7:46 pm

Nonstop4h 37m

$495

Panama CityRaleigh

PTY - RDU

PTYRDU

Panama City Tocumen Intl

Wed 12/17

8:57 am-1:25 pm

Nonstop4h 28m

Raleigh-Durham

Wed 12/31

3:11 pm-7:46 pm

Nonstop4h 35m

$495

Panama CityRaleigh

PTY - RDU

PTYRDU

Panama City Tocumen Intl

Wed 12/24

8:57 am-1:25 pm

Nonstop4h 28m

Raleigh-Durham

Mon 1/5

3:09 pm-7:46 pm

Nonstop4h 37m

$495

Panama CityRaleigh

PTY - RDU

PTYRDU

Panama City Tocumen Intl

Wed 12/17

3:46 pm-12:18 am

1 stop8h 32m

Raleigh-Durham

Wed 12/31

9:58 am-8:00 pm

1 stop10h 02m

$501

Panama CityRaleigh

PTY - RDU

PTYRDU

Panama City Tocumen Intl

Wed 12/17

4:41 pm-3:46 pm

1 stop23h 05m

Raleigh-Durham

Wed 12/31

6:31 am-5:07 pm

2 stops34h 36m

$501

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

Showing 1-10 of 46 results
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Best time to book a flight from Panama City to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to North Carolina

What is the cheapest month to book a flight from Panama City to North Carolina?

Currently, June is the cheapest month in which you can book a flight from Panama City to North Carolina (average of $273). Flying from Panama City to North Carolina in April is currently the most expensive (average of $394). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to NC?

Find hourly flight availability from Panama City to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

When flying from Panama City to North Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 15% versus a flight in the afternoon.

What is the cheapest day to fly from Panama City to North Carolina?

Use this chart to determine the cheapest time to fly round-trip from Panama City to North Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Panama City to North Carolina flight should consider departing on Tuesday mornings when fares are most often at their lowest. Wednesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Panama City to North Carolina?

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated October 16, 2025.
Read through reviews of airlines operating flights from Panama City to North Carolina, such as Delta, Copa Airlines, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,978 reviews

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!
Delta
7.9
Good
7,978 reviews
Delta
7.9
Good
7,978 reviews

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!
Copa Airlines
7.6
Good
1,551 reviews
Delta
7.9
Good
7,978 reviews

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!
United Airlines
7.4
Good
8,982 reviews
Delta
7.9
Good
7,978 reviews

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
7,978 reviews

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!

Related info for your journey

Find useful and relevant information for your journey from Panama City to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to North Carolina?

    If you book a flight to North Carolina from Panama City, you will be flying from Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City.

  • How popular is this Panama City to North Carolina flight route?

    Within the past month, 1 users have taken a look at flights from Panama City Tocumen Intl to North Carolina.

  • How long is the flight from Panama City to North Carolina?

    Airlines like American Airlines, United Airlines, and Copa Airlines fly from Panama City to North Carolina in about 4h 18m. The time it takes to get you to your destination can typically vary by up to 24h 37m. There are 1851 mi between Panama City and North Carolina. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Panama City to North Carolina one-way?

    One-way options have recently been found by users for as low as $305 on Delta. Other airlines that offer cheap prices include American Airlines from $308 and United Airlines from $317 one-way.

  • What are the most popular routes from Panama City to North Carolina?

    While some choose either Panama City Tocumen Intl - Raleigh-Durham or Panama City Tocumen Intl - Greensboro/H. Point, Panama City Tocumen Intl - Charlotte Douglas is the most popular route from Panama City to North Carolina.

  • What are the cheapest flights from Panama City to North Carolina?

    On average you can expect to pay $510 for a flight from Panama City to North Carolina. The cheapest flight overall is $280 while the most popular route, (Panama City Tocumen Intl - Charlotte Douglas) is currently priced at $409.

  • Can I find deals for flights from Panama City to North Carolina that include hotel bookings?

    Yes. In addition to deals on Panama City to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to North Carolina.

  • Can I find deals for business class flights from Panama City to North Carolina?

    Yes. Cheapflights offers flight deals from Panama City to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to North Carolina?

    Currently, June is the cheapest month in which you can book a flight from Panama City to North Carolina (average of $273). Flying from Panama City to North Carolina in April is currently the most expensive (average of $394). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Panama City to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Panama City to North Carolina

Discover the top 4 airlines that operate flights from Panama City to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$298Average$448FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$312Average$500FlexibilityNo cancel feeOn-time71%
DeltaCheapest$361Average$538FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$436Average$531FlexibilityNo cancel feeOn-time69%

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