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Missouri

$72+ Cheap flights from South Carolina to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — STL
Sep 1 — Sep 81
Mon 9/1
Mon 9/8
1 adult, Economy
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Cheap flight deals from South Carolina to Missouri

Keep the following information in mind while searching for South Carolina to Missouri flight deals. Data was last updated August 27, 2025.

Round-trip from

$203
(FlightHub)

One-way from

$72
(Priceline)

Popular in

June

Cheapest in

February

Average price

$264

Good round-trip deal

$373 or less

Good one-way deal

$178 or less
From South Carolina to Missouri
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One-way flight from South Carolina to Missouri
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Highest demand for flights based on searches. 12% potential increase in price ($49 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a round-trip flight from South Carolina to Missouri.
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Price to beat on a one-way flight from South Carolina to Missouri.
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Find flight deals from South Carolina to Missouri

Cheapest flights from South Carolina to Missouri
Explore the most affordable flight options available from South Carolina to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 27, 2025.

This FlightHub deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/181:48 pmCLT - MCI
1 stop10h 19mSpirit Airlines
Sat 9/205:15 amMCI - CLT
1 stop6h 38mSpirit Airlines
Deal found 8/25$194
This Cheapflightsfares deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/201:53 pmCLT - MCI
1 stop10h 14mSpirit Airlines
Mon 9/225:15 amMCI - CLT
1 stop6h 38mSpirit Airlines
Deal found 8/25$200
This FlightHub deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/275:55 amCLT - MCI
1 stop11h 21mSpirit Airlines
Wed 12/1712:13 pmMCI - CLT
1 stop11h 46mSpirit Airlines
Deal found 8/26$203
This Cheapflightsfares deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/261:48 pmCLT - MCI
1 stop10h 19mSpirit Airlines
Mon 9/2911:13 amMCI - CLT
1 stop10h 46mSpirit Airlines
Deal found 8/27$204
This FlightHub deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/181:48 pmCLT - MCI
1 stop10h 19mSpirit Airlines
Thu 9/255:15 amMCI - CLT
1 stop6h 38mSpirit Airlines
Deal found 8/25$207
This CheapOair deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/191:48 pmCLT - MCI
1 stop10h 19mSpirit Airlines
Mon 9/225:15 amMCI - CLT
1 stop12h 06mSpirit Airlines
Deal found 8/26$209
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/302:52 pmCAE - STL
1 stop5h 07mUnited Airlines
Sun 8/318:15 amSTL - CAE
1 stop5h 00mUnited Airlines
Deal found 8/26$211
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/311:04 amCAE - STL
1 stop5h 40mUnited Airlines
Sat 9/66:35 amSTL - CAE
2 stops6h 40mUnited Airlines
Deal found 8/27$216
This Cheapflightsfares deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/171:53 pmCLT - MCI
1 stop10h 14mSpirit Airlines
Sun 9/215:15 amMCI - CLT
1 stop6h 38mSpirit Airlines
Deal found 8/27$216
This FlightHub deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/21:48 pmCLT - MCI
1 stop10h 19mSpirit Airlines
Mon 10/65:11 pmMCI - CLT
1 stop15h 13mSpirit Airlines
Deal found 8/25$221
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/196:30 pmCLT - STL
1 stop6h 14mUnited Airlines
Mon 9/226:35 amSTL - CLT
2 stops6h 34mUnited Airlines
Deal found 8/26$222
This FlightHub deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/610:11 pmCLT - MCI
1 stop11h 53mSpirit Airlines
Sat 11/81:44 pmMCI - CLT
1 stop21h 50mSpirit Airlines
Deal found 8/27$223

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 27, 2025.
Use the filters below to find and compare flights from South Carolina to Missouri that are best for you.

Fly from

South Carolina

Fly to

Missouri

Route

Depart

Return

Price

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Thu 9/18

1:48 pm-11:07 pm

1 stop10h 19m

Kansas City

Sat 9/20

5:15 am-12:53 pm

1 stop6h 38m

$194

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Sat 9/20

1:53 pm-11:07 pm

1 stop10h 14m

Kansas City

Mon 9/22

5:15 am-12:53 pm

1 stop6h 38m

$200

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Mon 10/27

5:55 am-4:16 pm

1 stop11h 21m

Kansas City

Wed 12/17

12:13 pm-12:59 am

1 stop11h 46m

$203

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Fri 9/26

1:48 pm-11:07 pm

1 stop10h 19m

Kansas City

Mon 9/29

11:13 am-10:59 pm

1 stop10h 46m

$204

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Sat 9/27

1:53 pm-11:07 pm

1 stop10h 14m

Kansas City

Mon 9/29

11:13 am-10:59 pm

1 stop10h 46m

$205

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Thu 11/6

10:11 pm-9:04 am

1 stop11h 53m

Kansas City

Mon 11/10

12:13 pm-12:59 am

1 stop11h 46m

$205

ColumbiaSt. Louis

CAE - STL

CAESTL

Columbia Metropolitan

Wed 2/18

2:59 pm-6:04 pm

1 stop4h 05m

Lambert-St Louis

Sat 2/21

6:00 am-11:20 am

1 stop4h 20m

$217

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Fri 9/19

6:30 pm-11:44 pm

1 stop6h 14m

Lambert-St Louis

Mon 9/22

6:35 am-2:09 pm

2 stops6h 34m

$222

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 9/20

6:55 am-3:44 pm

2 stops9h 49m

Lambert-St Louis

Thu 9/25

5:00 am-10:22 am

1 stop4h 22m

$222

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 10/15

6:30 am-10:49 am

1 stop5h 19m

Lambert-St Louis

Wed 10/22

5:00 am-2:10 pm

2 stops8h 10m

$222

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/25

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Missouri

What is the cheapest month to book a flight from South Carolina to Missouri?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Missouri (average of $311). Flying from South Carolina to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MO?

Find hourly flight availability from South Carolina to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 27, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Missouri as you normally would.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated August 27, 2025.
Read through reviews of airlines operating flights from South Carolina to Missouri, such as Southwest, Delta, and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,977 reviews
Southwest
8.0
Very good
4,241 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,241 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,030 reviews
Southwest
8.0
Very good
4,241 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this South Carolina to Missouri flight route?

    The South Carolina to Missouri flight path was viewed by 6 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from South Carolina to Missouri?

    A quick flight from South Carolina to Missouri can take about 4h 05m. Spirit Airlines provides one of the quickest options available for as low as $217. Airlines will cover a distance of 611 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from South Carolina to Missouri one-way?

    One-way options have recently been found by users for as low as $72 on Frontier. Other airlines that offer cheap prices include Spirit Airlines from $89 and Delta from $126 one-way.

  • Can I find deals for flights from South Carolina to Missouri that include hotel bookings?

    Yes. In addition to deals on South Carolina to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Missouri.

  • Can I find deals for business class flights from South Carolina to Missouri?

    Yes. Cheapflights offers flight deals from South Carolina to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Missouri?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Missouri (average of $311). Flying from South Carolina to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from South Carolina to Missouri

Discover the top 4 airlines that operate flights from South Carolina to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$139Average$353FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$199Average$225FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$204Average$392FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$226Average$392FlexibilityNo cancel feeOn-time63%

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