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Missouri

$90+ Cheap flights from South Carolina to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/24. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — STL
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from South Carolina to Missouri

Keep the following information in mind while searching for South Carolina to Missouri flight deals. Data was last updated junio 12, 2025.

Round-trip from

$155
(Southwest)

One-way from

$90
(Mytrip)

Popular in

June

Cheapest in

February

Average price

$417

Good round-trip deal

$314 or less

Good one-way deal

$271 or less
From South Carolina to Missouri
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One-way flight from South Carolina to Missouri
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Highest demand for flights based on searches. 7% potential increase in price ($30 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Price to beat on a round-trip flight from South Carolina to Missouri.
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Price to beat on a one-way flight from South Carolina to Missouri.
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Find flight deals from South Carolina to Missouri

Cheapest flights from South Carolina to Missouri
Explore the most affordable flight options available from South Carolina to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/279:30 amCLT - MCI
2 stops10h 35mSouthwest
lun. 9/297:25 amMCI - CLT
1 stop10h 35mSouthwest
Deal found 6/12$155
This FlightHub deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/115:04 pmCLT - STL
1 stop15h 45mSpirit Airlines
dom. 9/148:44 amSTL - CLT
1 stop6h 15mSpirit Airlines
Deal found 6/11$187
This FlightHub deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/182:16 pmCLT - STL
1 stop10h 31mFrontier
sáb. 8/237:54 pmSTL - CLT
1 stop19h 43mFrontier
Deal found 6/9$193
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/1010:53 amCHS - STL
1 stop23h 59mSpirit Airlines
jue. 7/1710:47 amSTL - CHS
1 stop22h 06mSpirit Airlines
Deal found 6/11$194
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/77:13 amCLT - STL
Nonstop1h 51mAmerican Airlines
lun. 8/116:26 amSTL - CLT
Nonstop1h 58mAmerican Airlines
Deal found 6/10$197
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/2611:28 amCLT - MCI
2 stops23h 32mSpirit Airlines
lun. 6/3011:00 amMCI - CLT
1 stop7h 01mSpirit Airlines
Deal found 6/10$208
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/257:50 pmCLT - STL
Nonstop2h 00mSouthwest
sáb. 8/301:45 pmSTL - CLT
Nonstop1h 50mSouthwest
Deal found 6/11$209
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/274:03 pmCAE - STL
1 stop6h 01mAmerican Airlines
mié. 9/36:02 amSTL - CAE
1 stop6h 22mAmerican Airlines
Deal found 6/10$211
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/235:30 amCLT - STL
1 stop6h 10mDelta
lun. 9/295:40 pmSTL - CLT
1 stop5h 14mDelta
Deal found 6/11$217
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/265:25 pmSAV - STL
1 stop3h 40mSouthwest
mié. 8/272:15 pmSTL - SAV
1 stop5h 10mSouthwest
Deal found 6/10$217
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/2611:10 amCAE - STL
1 stop5h 56mDelta
sáb. 9/67:00 amSTL - CAE
1 stop4h 19mDelta
Deal found 6/10$217
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/182:00 pmCLT - MCI
1 stop4h 37mDelta
jue. 8/218:00 amMCI - CLT
1 stop5h 58mDelta
Deal found 6/11$217

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from South Carolina to Missouri that are best for you.

Fly from

South Carolina

Fly to

Missouri

Route

Depart

Return

Price

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

sáb. 9/27

9:30 am-7:05 pm

2 stops10h 35m

Kansas City

lun. 9/29

7:25 am-7:00 pm

1 stop10h 35m

$155

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

jue. 9/11

5:04 pm-7:49 am

1 stop15h 45m

Lambert-St Louis

dom. 9/14

8:44 am-3:59 pm

1 stop6h 15m

$187

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

lun. 8/18

2:16 pm-11:47 pm

1 stop10h 31m

Lambert-St Louis

sáb. 8/23

7:54 pm-4:37 pm

1 stop19h 43m

$193

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

jue. 7/10

10:53 am-9:52 am

1 stop23h 59m

Lambert-St Louis

jue. 7/17

10:47 am-9:53 am

1 stop22h 06m

$194

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

jue. 8/7

7:13 am-8:04 am

Nonstop1h 51m

Lambert-St Louis

lun. 8/11

6:26 am-9:24 am

Nonstop1h 58m

$197

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

jue. 6/26

11:28 am-10:00 am

2 stops23h 32m

Kansas City

lun. 6/30

11:00 am-7:01 pm

1 stop7h 01m

$208

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

lun. 8/25

7:50 pm-8:50 pm

Nonstop2h 00m

Lambert-St Louis

sáb. 8/30

1:45 pm-4:35 pm

Nonstop1h 50m

$209

ColumbiaSt. Louis

CAE - STL

CAESTL

Columbia Metropolitan

mié. 8/27

4:03 pm-9:04 pm

1 stop6h 01m

Lambert-St Louis

mié. 9/3

6:02 am-1:24 pm

1 stop6h 22m

$211

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

mar. 9/23

5:30 am-10:40 am

1 stop6h 10m

Lambert-St Louis

lun. 9/29

5:40 pm-11:54 pm

1 stop5h 14m

$217

ColumbiaSt. Louis

CAE - STL

CAESTL

Columbia Metropolitan

mar. 8/26

11:10 am-4:06 pm

1 stop5h 56m

Lambert-St Louis

sáb. 9/6

7:00 am-12:19 pm

1 stop4h 19m

$217

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Missouri

What is the cheapest month to book a flight from South Carolina to Missouri?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Missouri (average of $311). Flying from South Carolina to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MO?

Find hourly flight availability from South Carolina to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Missouri as you normally would.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated junio 12, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest and Delta from South Carolina to Missouri to help guide your decision. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,287 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,946 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,790 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this South Carolina to Missouri flight route?

    The South Carolina to Missouri flight path was viewed by 5 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from South Carolina to Missouri one-way?

    One-way options have recently been found by users for as low as $90 on Spirit Airlines. Other airlines that offer cheap prices include Southwest from $97 and American Airlines from $105 one-way.

  • Can I find deals for flights from South Carolina to Missouri that include hotel bookings?

    Yes. In addition to deals on South Carolina to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Missouri.

  • Can I find deals for business class flights from South Carolina to Missouri?

    Yes. Cheapflights offers flight deals from South Carolina to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Missouri?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Missouri (average of $311). Flying from South Carolina to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to Missouri

Discover the top 5 airlines that operate flights from South Carolina to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$139Average$354FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$170Average$381FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$174Average$366FlexibilityNo cancel feeOn-time69%
Spirit AirlinesCheapest$199Average$243FlexibilityNo cancel feeOn-time65%
SouthwestCheapest$286Average$391FlexibilityNo cancel feeOn-time63%

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