$67+ Cheap flights from San Diego (SAN) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — STL
May 5 — May 121
1 adult, Economy
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Find cheap flights from San Diego to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Missouri
Keep the following information in mind while searching for San Diego to Missouri flight deals. Data was last updated April 30, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $221 (CheapOair) |
One-way from | $67 (Cheapflightsfares) |
Popular in | March |
Cheapest in | August |
Average price | $333 |
Good round-trip deal | $411 or less |
Good one-way deal | $238 or less |
Find flight deals from San Diego to Missouri
Cheapest flights from San Diego to MissouriExplore the most affordable flight options available from San Diego to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.
Explore the most affordable flight options available from San Diego to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.
This CheapOair deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/118:54 pmSAN - MCI
1 stop20h 57mFrontier
Thu 5/158:51 pmMCI - SAN
1 stop14h 47mFrontier
Deal found 4/29![Frontier logo]()
$221
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/296:15 amSAN - MCI
2 stops11h 57mSpirit Airlines
Sun 6/110:15 amMCI - SAN
2 stops22h 58mSpirit Airlines
Deal found 4/29![Spirit Airlines logo]()
$237
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/116:20 amSAN - MCI
1 stop7h 01mDelta
Fri 6/134:12 pmMCI - SAN
1 stop9h 08mDelta
Deal found 4/29![Delta logo]()
$249
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/273:10 pmSAN - SGF
1 stop6h 44mAmerican Airlines
Mon 6/97:27 pmSGF - SAN
1 stop5h 30mAmerican Airlines
Deal found 4/29![American Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/711:08 amSAN - SGF
2 stops8h 49mUnited Airlines
Tue 10/146:00 amSGF - SAN
1 stop5h 09mUnited Airlines
Deal found 4/29![United Airlines logo]()
$274
This Trip.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/158:54 pmSAN - STL
1 stop10h 15mFrontier
Mon 5/196:53 pmSTL - SAN
2 stops30h 26mFrontier
Deal found 4/29![Frontier logo]()
$277
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/139:40 pmSAN - STL
1 stop9h 24mDelta
Mon 6/163:42 pmSTL - SAN
1 stop9h 47mDelta
Deal found 4/28![Delta logo]()
$278
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/36:15 amSAN - STL
2 stops8h 16mUnited Airlines
Thu 6/51:42 pmSTL - SAN
1 stop5h 32mUnited Airlines
Deal found 4/29![United Airlines logo]()
$284
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/2010:45 pmSAN - MCI
1 stop7h 49mAmerican Airlines
Sat 8/22:28 pmMCI - SAN
1 stop6h 50mAmerican Airlines
Deal found 4/28![American Airlines logo]()
$304
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/38:48 pmSAN - STL
2 stops34h 27mMultiple Airlines
Thu 6/55:15 pmSTL - SAN
3 stops26h 48mMultiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$311
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/195:50 pmSAN - STL
2 stops14h 43mSpirit Airlines
Sun 6/226:12 pmSTL - SAN
2 stops26h 14mSpirit Airlines
Deal found 4/29![Spirit Airlines logo]()
$321
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/284:30 pmSAN - MCI
Nonstop3h 10mSouthwest
Sun 8/316:40 amMCI - SAN
1 stop5h 00mSouthwest
Deal found 4/29![Southwest logo]()
$324
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from San Diego to Missouri that are best for you.
Fly from
San Diego
Fly to
Missouri
Route
Depart
Return
Price
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Sun 5/11
8:54 pm-7:51 pm
1 stop20h 57m
Kansas City
Thu 5/15
8:51 pm-9:38 am
1 stop14h 47m
$221
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Thu 5/29
6:15 am-8:12 pm
2 stops11h 57m
Kansas City
Sun 6/1
10:15 am-7:13 am
2 stops22h 58m
$237
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Wed 6/11
6:20 am-3:21 pm
1 stop7h 01m
Kansas City
Fri 6/13
4:12 pm-11:20 pm
1 stop9h 08m
$249
San DiegoSpringfield
SAN - SGF
SANSGF
San Diego
Tue 5/27
3:10 pm-11:54 pm
1 stop6h 44m
Springfield-Branson
Mon 6/9
7:27 pm-10:57 pm
1 stop5h 30m
$269
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Thu 5/15
8:54 pm-9:09 am
1 stop10h 15m
Lambert-St Louis
Mon 5/19
6:53 pm-11:19 pm
2 stops30h 26m
$277
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Fri 6/13
9:40 pm-9:04 am
1 stop9h 24m
Lambert-St Louis
Mon 6/16
3:42 pm-11:29 pm
1 stop9h 47m
$278
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Tue 6/3
6:15 am-4:31 pm
2 stops8h 16m
Lambert-St Louis
Thu 6/5
1:42 pm-5:14 pm
1 stop5h 32m
$284
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Sun 7/20
10:45 pm-8:34 am
1 stop7h 49m
Kansas City
Sat 8/2
2:28 pm-7:18 pm
1 stop6h 50m
$304
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Tue 6/3
8:48 pm-9:15 am
2 stops34h 27m
Lambert-St Louis
Thu 6/5
5:15 pm-6:03 pm
3 stops26h 48m
$311
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Thu 6/19
5:50 pm-10:33 am
2 stops14h 43m
Lambert-St Louis
Sun 6/22
6:12 pm-6:26 pm
2 stops26h 14m
$321
Showing 1-10 of 39 results
Best time to book a flight from San Diego to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Missouri
What is the cheapest month to book a flight from San Diego to Missouri?
Currently, August is the cheapest month in which you can book a flight from San Diego to Missouri (average of $311). Flying from San Diego to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to MO?
Find hourly flight availability from San Diego to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.
When flying from San Diego to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Rainfall in Missouri by month
Plan your trip to Missouri by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.
Temperature in Missouri by month
Plan your trip to Missouri by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 30, 2025.
To help decide which airline to fly from San Diego to Missouri, see what other customers have to say about Alaska Airlines, Southwest and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.2
Comfort
7.9
Entertainment
7.1
Food
7.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentJames,Apr 2025
LAX - SFO
Crew
8.5
Boarding
8.2
Comfort
7.9
Entertainment
7.1
Food
7.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentJames,Apr 2025
LAX - SFO
Crew
8.5
Boarding
8.2
Comfort
7.9
Entertainment
7.1
Food
7.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentJames,Apr 2025
LAX - SFO
Crew
8.5
Boarding
8.2
Comfort
7.9
Entertainment
7.1
Food
7.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentJames,Apr 2025
LAX - SFO
Crew
8.5
Boarding
8.2
Comfort
7.9
Entertainment
7.1
Food
7.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentJames,Apr 2025
LAX - SFO
Crew
8.5
Boarding
8.2
Comfort
7.9
Entertainment
7.1
Food
7.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentJames,Apr 2025
LAX - SFO
Related info for your journey
Find useful and relevant information for your journey from San Diego to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Top 7 airlines flying from San Diego to Missouri
Discover the top 7 airlines that operate flights from San Diego to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$116 | Average$252 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$133 | Average$237 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$190 | Average$314 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$218 | Average$442 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$233 | Average$388 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$273 | Average$713 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$275 | Average$483 | FlexibilityNo cancel fee | On-time63% |