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$72+ Cheap flights from San Diego (SAN) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — STL
Oct 29 — Nov 51
Wed 10/29
Wed 11/5
1 adult, Economy
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Cheap flight deals from San Diego to Missouri

Keep the following information in mind while searching for San Diego to Missouri flight deals. Data was last updated September 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$144
(Gotogate)

One-way from

$72
(Trip.com)

Popular in

March

Cheapest in

August

Average price

$360

Good round-trip deal

$327 or less

Good one-way deal

$218 or less
Provider with most accurate pricing for San Diego-Kansas City flight deals.
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Provider most trusted by Cheapflights users for San Diego-Kansas City flights.
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From San Diego to Missouri
Search Deals
One-way flight from San Diego to Missouri
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($15 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from San Diego to Missouri.
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Price to beat on a one-way flight from San Diego to Missouri.
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Find flight deals from San Diego to Missouri

Cheapest flights from San Diego to Missouri
Explore the most affordable flight options available from San Diego to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2025.

This Gotogate deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/133:59 pmSAN - STL
1 stop19h 58mFrontier
Wed 11/197:45 pmSTL - SAN
1 stop18h 25mFrontier
Deal found 9/28$144
This Booking.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:41 amSAN - STL
1 stop24h 26mFrontier
Fri 10/247:52 pmSTL - SAN
1 stop19h 36mFrontier
Deal found 9/27$145
This Booking.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:41 amSAN - STL
1 stop24h 26mFrontier
Mon 10/207:52 pmSTL - SAN
1 stop5h 58mFrontier
Deal found 9/27$146
This Priceline deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/138:11 amSAN - STL
1 stop9h 15mFrontier
Fri 10/177:52 pmSTL - SAN
1 stop5h 58mFrontier
Deal found 9/28$157
This Booking.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:41 amSAN - STL
1 stop24h 26mFrontier
Sun 11/912:10 pmSTL - SAN
1 stop9h 04mFrontier
Deal found 9/28$159
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/257:00 amSAN - MCI
1 stop8h 55mFrontier
Sat 11/18:28 pmMCI - SAN
1 stop17h 49mFrontier
Deal found 9/27$177
This Frontier deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/108:11 amSAN - STL
1 stop12h 03mFrontier
Sun 10/1210:17 amSTL - SAN
1 stop10h 11mFrontier
Deal found 9/28$177
This Frontier deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:41 amSAN - MCI
1 stop9h 14mFrontier
Mon 10/278:38 pmMCI - SAN
1 stop5h 12mFrontier
Deal found 9/28$190
This Gotogate deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:41 amSAN - STL
1 stop24h 26mFrontier
Sun 10/1910:17 amSTL - SAN
1 stop10h 11mFrontier
Deal found 9/28$190
This Booking.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:15 amSAN - STL
1 stop23h 51mFrontier
Mon 10/139:59 pmSTL - SAN
1 stop25h 21mFrontier
Deal found 9/27$192
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/139:14 amSAN - MCI
2 stops8h 19mFrontier
Mon 11/178:28 pmMCI - SAN
1 stop27h 11mFrontier
Deal found 9/27$193
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:00 pmSAN - MCI
1 stop23h 33mFrontier
Sat 11/18:28 pmMCI - SAN
1 stop17h 49mFrontier
Deal found 9/27$194

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 29, 2025.
Use the filters below to find and compare flights from San Diego to Missouri that are best for you.

Fly from

San Diego

Fly to

Missouri

Route

Depart

Return

Price

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Fri 10/17

9:03 pm-9:07 am

1 stop10h 04m

Lambert-St Louis

Tue 10/21

7:52 pm-11:50 pm

1 stop5h 58m

$144

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Sat 11/1

6:41 am-10:07 am

1 stop25h 26m

Lambert-St Louis

Sun 11/2

7:45 pm-11:50 pm

1 stop6h 05m

$145

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Sat 11/1

6:41 am-10:07 am

1 stop25h 26m

Lambert-St Louis

Tue 11/4

7:45 pm-9:39 pm

1 stop27h 54m

$145

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Fri 10/10

8:11 am-10:14 pm

1 stop12h 03m

Lambert-St Louis

Mon 10/13

9:59 pm-9:20 pm

1 stop25h 21m

$145

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Wed 11/5

6:41 am-9:07 am

1 stop24h 26m

Lambert-St Louis

Sun 11/9

12:10 pm-7:14 pm

1 stop9h 04m

$159

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

Sat 11/1

6:41 am-7:38 pm

1 stop10h 57m

Kansas City

Tue 11/4

6:49 pm-11:52 am

1 stop19h 03m

$196

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

Fri 10/17

8:11 am-5:55 pm

2 stops31h 44m

Kansas City

Fri 10/31

8:28 pm-9:27 am

1 stop14h 59m

$203

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Sun 10/12

6:41 am-9:07 am

1 stop24h 26m

Lambert-St Louis

Thu 10/16

10:17 am-6:28 pm

1 stop10h 11m

$205

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

Thu 10/30

3:59 pm-10:17 am

2 stops16h 18m

Kansas City

Sun 11/2

12:31 pm-4:40 pm

1 stop6h 09m

$221

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Sun 11/2

5:41 am-8:07 am

1 stop24h 26m

Lambert-St Louis

Wed 11/5

7:45 pm-12:35 pm

2 stops18h 50m

$223

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/28

Showing 1-10 of 55 results
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Best time to book a flight from San Diego to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Missouri

What is the cheapest month to book a flight from San Diego to Missouri?

Currently, August is the cheapest month in which you can book a flight from San Diego to Missouri (average of $311). Flying from San Diego to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to MO?

Find hourly flight availability from San Diego to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 29, 2025.

When flying from San Diego to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated September 29, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from San Diego to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Food

7.0

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Food

7.0

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,964 reviews
Southwest
8.0
Very good
4,246 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Food

7.0

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
8,924 reviews
Southwest
8.0
Very good
4,246 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Food

7.0

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Food

7.0

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Frontier
5.8
Fair
3,158 reviews
Southwest
8.0
Very good
4,246 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Food

7.0

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Diego to Missouri?

    Most people fly from San Diego (SAN) if they book a flight from San Diego to Missouri. San Diego is conveniently located just 2.6 mi from San Diego’s city center.

  • How popular is this San Diego to Missouri flight route?

    Within the past month, 8 users have taken a look at flights from San Diego to Missouri.

  • How long is the flight from San Diego to Missouri?

    A quick flight from San Diego to Missouri can take about 6h 58m. Frontier provides one of the quickest options available for as low as $269. Airlines will cover a distance of 1330 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from San Diego to Missouri one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $135. However, be on the lookout for offers from Southwest and United Airlines, as they are both options that can get you from San Diego to Missouri for a low price.

  • What are the most popular routes from San Diego to Missouri?

    The most popular flight routes from San Diego to Missouri are San Diego - Kansas City, San Diego - Lambert-St Louis and San Diego - Springfield-Branson.

  • What are the cheapest flights from San Diego to Missouri?

    The cheapest flight price from San Diego to Missouri is $166. On average you can expect to pay $343. The most popular route, (San Diego - Kansas City), can usually be booked for $204.

  • Can I find deals for flights from San Diego to Missouri that include hotel bookings?

    Yes. In addition to deals on San Diego to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Missouri.

  • Can I find deals for business class flights from San Diego to Missouri?

    Yes. Cheapflights offers flight deals from San Diego to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Missouri?

    Currently, August is the cheapest month in which you can book a flight from San Diego to Missouri (average of $311). Flying from San Diego to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for San Diego to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from San Diego to Missouri

Discover the top 7 airlines that operate flights from San Diego to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$105Average$230FlexibilityNo cancel feeOn-time65%
FrontierCheapest$117Average$284FlexibilityNo cancel feeOn-time62%
DeltaCheapest$138Average$283FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$221Average$414FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$236Average$392FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$262Average$478FlexibilityNo cancel feeOn-time63%
Alaska AirlinesCheapest$372Average$713FlexibilityNo cancel feeOn-time75%

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