$68+ Cheap flights from San Diego (SAN) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — STL
Apr 25 — May 21
Round-trip
1 adult, Economy
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Cheapest flights from San Diego to MissouriExplore the most affordable flight options available from San Diego to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.
Explore the most affordable flight options available from San Diego to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:25 am
SAN
- STL
1 stop10h 58m
Frontier
Tue 6/28:08 pm
STL
- SAN
1 stop14h 34m
Frontier
Deal found 3/25![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:25 pm
SAN
- STL
1 stop29h 07m
Frontier
Mon 5/48:17 pm
STL
- SAN
1 stop14h 25m
Frontier
Deal found 3/24![Frontier logo]()
$159
This Orbitz deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:25 am
SAN
- STL
1 stop10h 56m
Frontier
Mon 4/278:17 pm
STL
- SAN
1 stop28h 49m
Frontier
Deal found 3/24![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:25 am
SAN
- STL
1 stop11h 07m
Frontier
Thu 5/78:08 pm
STL
- SAN
1 stop14h 34m
Frontier
Deal found 3/25![Frontier logo]()
$169
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:34 pm
SAN
- STL
1 stop20h 32m
Frontier
Fri 5/89:18 pm
STL
- SAN
1 stop25h 54m
Frontier
Deal found 3/25![Frontier logo]()
$171
This Booking.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:12 pm
SAN
- STL
1 stop28h 48m
Frontier
Mon 5/43:21 pm
STL
- SAN
1 stop9h 40m
Frontier
Deal found 3/20![Frontier logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:42 am
SAN
- MCI
1 stop23h 48m
Frontier
Tue 5/52:34 pm
MCI
- SAN
1 stop20h 08m
Frontier
Deal found 3/23![Frontier logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:25 pm
SAN
- STL
1 stop29h 07m
Frontier
Sun 5/38:06 pm
STL
- SAN
1 stop14h 28m
Frontier
Deal found 3/24![Frontier logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:25 am
SAN
- STL
1 stop10h 56m
Frontier
Sat 5/98:08 pm
STL
- SAN
1 stop14h 34m
Frontier
Deal found 3/22![Frontier logo]()
$177
This Expedia deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/109:28 pm
SAN
- MCI
1 stop20h 30m
Frontier
Sat 4/252:51 pm
MCI
- SAN
1 stop10h 15m
Frontier
Deal found 3/21![Frontier logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:25 pm
SAN
- STL
1 stop29h 07m
Frontier
Tue 5/56:51 pm
STL
- SAN
2 stops15h 51m
Frontier
Deal found 3/24![Frontier logo]()
$182
This Frontier deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:25 am
SAN
- MCI
1 stop5h 05m
Frontier
Wed 5/62:34 pm
MCI
- SAN
1 stop11h 16m
Frontier
Deal found 3/24![Frontier logo]()
$185
Best flights from San Diego to MissouriDiscover carefully curated flight deals from San Diego to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2026.
Discover carefully curated flight deals from San Diego to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2026.
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2610:40 pm
SAN
- STL
1 stop7h 05m
Southwest
Tue 6/25:35 am
STL
- SAN
2 stops7h 45m
Southwest
Deal found 3/22![Southwest logo]()
$204
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/410:40 pm
SAN
- MCI
1 stop9h 53m
United Airlines
Wed 5/611:29 am
MCI
- SAN
2 stops10h 34m
United Airlines
Deal found 3/24![United Airlines logo]()
$312
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:15 am
SAN
- MCI
1 stop5h 05m
Delta
Sun 4/267:42 am
MCI
- SAN
1 stop8h 56m
Delta
Deal found 3/22![Delta logo]()
$318
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1810:40 pm
SAN
- COU
1 stop9h 06m
American Airlines
Sat 4/255:21 pm
COU
- SAN
1 stop8h 35m
American Airlines
Deal found 3/23![American Airlines logo]()
$338
This Alaska Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/159:12 am
SAN
- STL
1 stop8h 18m
Alaska Airlines
Sat 4/186:11 pm
STL
- SAN
1 stop7h 45m
Alaska Airlines
Deal found 3/20![Alaska Airlines logo]()
$397
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:15 pm
SAN
- STL
2 stops7h 30m
Southwest
Tue 5/55:35 am
STL
- SAN
2 stops7h 45m
Southwest
Deal found 3/25![Southwest logo]()
$207
This KAYAK deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/59:15 am
SAN
- TBN
1 stop24h 30m
Multiple Airlines
Fri 5/812:15 pm
TBN
- SAN
1 stop25h 15m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$470
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/243:35 pm
SAN
- MCI
1 stop6h 00m
Southwest
Mon 4/278:05 pm
MCI
- SAN
1 stop5h 20m
Southwest
Deal found 3/25![Southwest logo]()
$226
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:50 pm
SAN
- STL
2 stops7h 25m
Southwest
Mon 4/206:00 pm
STL
- SAN
1 stop7h 05m
Southwest
Deal found 3/22![Southwest logo]()
$259
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:00 am
SAN
- COU
1 stop8h 03m
United Airlines
Sat 4/253:23 pm
COU
- SAN
2 stops11h 06m
United Airlines
Deal found 3/21![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2010:40 pm
SAN
- COU
1 stop9h 06m
American Airlines
Tue 4/2812:06 pm
COU
- SAN
2 stops8h 22m
American Airlines
Deal found 3/21![American Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/511:40 am
SAN
- STL
2 stops10h 45m
Delta
Fri 5/88:53 am
STL
- SAN
1 stop6h 24m
Delta
Deal found 3/21![Delta logo]()
$365
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1112:00 pm
SAN
- MCI
1 stop8h 20m
Southwest
Sat 4/1812:35 pm
MCI
- SAN
2 stops7h 15m
Southwest
Deal found 3/21![Southwest logo]()
$282
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:26 pm
SAN
- STL
1 stop9h 21m
United Airlines
Tue 5/511:15 am
STL
- SAN
2 stops10h 59m
United Airlines
Deal found 3/24![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:45 am
SAN
- MCI
Nonstop3h 05m
Southwest
Sat 5/161:10 pm
MCI
- SAN
1 stop6h 45m
Southwest
Deal found 3/23![Southwest logo]()
$294
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:40 pm
SAN
- MCI
2 stops12h 47m
United Airlines
Mon 4/274:06 pm
MCI
- SAN
1 stop6h 06m
United Airlines
Deal found 3/21![United Airlines logo]()
$372
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:55 am
SAN
- MCI
2 stops11h 04m
United Airlines
Tue 5/125:17 pm
MCI
- SAN
1 stop5h 55m
United Airlines
Deal found 3/22![United Airlines logo]()
$372
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/159:40 am
SAN
- MCI
Nonstop3h 10m
Southwest
Fri 4/178:20 pm
MCI
- SAN
1 stop4h 45m
Southwest
Deal found 3/25![Southwest logo]()
$311
This KAYAK deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:03 am
SAN
- TBN
1 stop28h 47m
Multiple Airlines
Fri 5/12:30 pm
TBN
- SAN
1 stop27h 57m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$522
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1510:40 pm
SAN
- COU
1 stop9h 06m
American Airlines
Tue 5/1912:06 pm
COU
- SAN
2 stops8h 22m
American Airlines
Deal found 3/22![American Airlines logo]()
$479
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:40 pm
SAN
- MCI
2 stops12h 47m
United Airlines
Sun 4/264:06 pm
MCI
- SAN
1 stop6h 06m
United Airlines
Deal found 3/22![United Airlines logo]()
$372
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:40 am
SAN
- MCI
1 stop6h 20m
Southwest
Fri 6/56:15 pm
MCI
- SAN
Nonstop3h 20m
Southwest
Deal found 3/21![Southwest logo]()
$319
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:00 am
SAN
- COU
1 stop8h 03m
United Airlines
Mon 4/133:23 pm
COU
- SAN
1 stop9h 36m
United Airlines
Deal found 3/25![United Airlines logo]()
$388
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:45 am
SAN
- TBN
1 stop27h 00m
Multiple Airlines
Thu 4/92:30 pm
TBN
- SAN
2 stops31h 56m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$590
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:35 am
SAN
- SGF
1 stop7h 45m
United Airlines
Wed 8/55:50 am
SGF
- SAN
1 stop5h 15m
United Airlines
Deal found 3/21![United Airlines logo]()
$401
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/132:15 pm
SAN
- MCI
1 stop7h 30m
Southwest
Wed 4/151:35 pm
MCI
- SAN
Nonstop3h 25m
Southwest
Deal found 3/24![Southwest logo]()
$369
This KAYAK deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/41:00 pm
SAN
- TBN
1 stop20h 45m
Multiple Airlines
Fri 5/812:15 pm
TBN
- SAN
1 stop25h 15m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$645
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1011:01 am
SAN
- SGF
2 stops9h 03m
United Airlines
Tue 4/145:07 pm
SGF
- SAN
1 stop6h 23m
United Airlines
Deal found 3/26![United Airlines logo]()
$404
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:35 am
SAN
- STL
1 stop5h 15m
Southwest
Sat 6/68:50 pm
STL
- SAN
Nonstop3h 45m
Southwest
Deal found 3/21![Southwest logo]()
$373
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:20 pm
SAN
- STL
Nonstop3h 35m
Southwest
Sun 5/315:35 am
STL
- SAN
1 stop5h 30m
Southwest
Deal found 3/21![Southwest logo]()
$373
Last-minute flights from San Diego to MissouriDiscover last-minute flight deals from San Diego to Missouri. Data last updated March 26, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Missouri. Data last updated March 26, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/109:28 pm
SAN
- MCI
1 stop20h 30m
Frontier
Sat 4/252:51 pm
MCI
- SAN
1 stop10h 15m
Frontier
Deal found 3/21![Frontier logo]()
$180
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/154:41 pm
SAN
- MCI
1 stop5h 26m
American Airlines
Tue 4/214:17 pm
MCI
- SAN
1 stop9h 16m
American Airlines
Deal found 3/25![American Airlines logo]()
$185
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:30 am
SAN
- MCI
1 stop4h 50m
Southwest
Tue 4/2112:25 pm
MCI
- SAN
2 stops7h 20m
Southwest
Deal found 3/25![Southwest logo]()
$190
This CheapOair deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:12 pm
SAN
- STL
1 stop28h 48m
Frontier
Sat 4/258:17 pm
STL
- SAN
1 stop14h 17m
Frontier
Deal found 3/24![Frontier logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:30 am
SAN
- STL
2 stops22h 00m
Frontier
Thu 4/168:06 pm
STL
- SAN
1 stop29h 53m
Frontier
Deal found 3/24![Frontier logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:42 am
SAN
- MCI
2 stops21h 16m
Frontier
Sat 4/252:51 pm
MCI
- SAN
1 stop10h 15m
Frontier
Deal found 3/22![Frontier logo]()
$193
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/211:03 pm
SAN
- MCI
1 stop8h 56m
American Airlines
Sat 4/252:11 pm
MCI
- SAN
1 stop8h 39m
American Airlines
Deal found 3/23![American Airlines logo]()
$197
This Orbitz deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:25 am
SAN
- STL
1 stop10h 56m
Frontier
Mon 4/278:17 pm
STL
- SAN
1 stop28h 49m
Frontier
Deal found 3/24![Frontier logo]()
$160
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:35 pm
SAN
- STL
1 stop6h 25m
Southwest
Tue 5/55:30 am
STL
- SAN
1 stop5h 25m
Southwest
Deal found 3/25![Southwest logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:30 am
SAN
- STL
2 stops21h 56m
Frontier
Mon 5/48:17 pm
STL
- SAN
1 stop14h 25m
Frontier
Deal found 3/24![Frontier logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:25 am
SAN
- STL
1 stop10h 56m
Frontier
Sat 5/98:08 pm
STL
- SAN
1 stop14h 34m
Frontier
Deal found 3/22![Frontier logo]()
$177
This Expedia deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:25 am
SAN
- STL
1 stop10h 56m
Frontier
Mon 5/43:21 pm
STL
- SAN
1 stop9h 40m
Frontier
Deal found 3/24![Frontier logo]()
$185
One-way flights from San Diego to MissouriSearch for one-way flight options from San Diego to Missouri. Find affordable one-way fares based on user searches. Data last updated March 26, 2026.
Search for one-way flight options from San Diego to Missouri. Find affordable one-way fares based on user searches. Data last updated March 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:25 am
SAN
- MCI
1 stop29h 24m
Frontier
Deal found 3/25![Frontier logo]()
$68
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:25 am
SAN
- STL
1 stop10h 58m
Frontier
Deal found 3/24![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:25 pm
SAN
- STL
1 stop29h 07m
Frontier
Deal found 3/25![Frontier logo]()
$78
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:37 am
SAN
- STL
1 stop7h 46m
Frontier
Deal found 3/25![Frontier logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:25 am
SAN
- MCI
1 stop29h 24m
Frontier
Deal found 3/25![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:15 am
SAN
- STL
1 stop10h 17m
Frontier
Deal found 3/23![Frontier logo]()
$82
This Expedia deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:25 am
SAN
- MCI
1 stop11h 33m
Frontier
Deal found 3/21![Frontier logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:25 pm
SAN
- MCI
1 stop23h 41m
Frontier
Deal found 3/22![Frontier logo]()
$89
This CheapOair deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:12 pm
SAN
- STL
1 stop28h 48m
Frontier
Deal found 3/24![Frontier logo]()
$92
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:09 pm
SAN
- MCI
1 stop6h 50m
American Airlines
Deal found 3/24![American Airlines logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:30 am
SAN
- MCI
1 stop25h 00m
Frontier
Deal found 3/25![Frontier logo]()
$96
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:40 pm
SAN
- STL
1 stop7h 15m
Southwest
Deal found 3/23![Southwest logo]()
$99
Find flight deals from San Diego to Missouri
Keep the following information in mind while searching for San Diego to Missouri flight deals. Data was last updated March 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $156 (Kiwi.com) |
One-way from | $68 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $473 |
Good round-trip deal | $216 or less |
Good one-way deal | $188 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from San Diego to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Tue 5/26
10:40 pm-7:45 am
1 stop7h 05m
Lambert-St Louis
Tue 6/2
5:35 am-11:20 am
2 stops7h 45m
$204
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Tue 4/28
12:15 pm-9:45 pm
2 stops7h 30m
Lambert-St Louis
Tue 5/5
5:35 am-11:20 am
2 stops7h 45m
$207
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Fri 4/24
3:35 pm-11:35 pm
1 stop6h 00m
Kansas City
Mon 4/27
8:05 pm-11:25 pm
1 stop5h 20m
$226
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Fri 4/17
1:50 pm-11:15 pm
2 stops7h 25m
Lambert-St Louis
Mon 4/20
6:00 pm-11:05 pm
1 stop7h 05m
$259
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Sat 4/11
12:00 pm-10:20 pm
1 stop8h 20m
Kansas City
Sat 4/18
12:35 pm-5:50 pm
2 stops7h 15m
$282
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Sat 5/9
6:45 am-11:50 am
Nonstop3h 05m
Kansas City
Sat 5/16
1:10 pm-5:55 pm
1 stop6h 45m
$294
Quickest round-trip
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Wed 4/15
9:40 am-2:50 pm
Nonstop3h 10m
Kansas City
Fri 4/17
8:20 pm-11:05 pm
1 stop4h 45m
$311
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Mon 5/4
10:40 pm-10:33 am
1 stop9h 53m
Kansas City
Wed 5/6
11:29 am-8:03 pm
2 stops10h 34m
$312
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Fri 4/24
6:15 am-1:20 pm
1 stop5h 05m
Kansas City
Sun 4/26
7:42 am-2:38 pm
1 stop8h 56m
$318
San DiegoKansas City
SAN - MCI
SANMCI
San Diego
Fri 6/5
6:40 am-3:00 pm
1 stop6h 20m
Kansas City
Fri 6/5
6:15 pm-7:35 pm
Nonstop3h 20m
$319
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Diego to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from San Diego with our price prediction graph.
SAN-STL
SAN-MCI
SAN-COU
SAN-TBN
SAN-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Missouri
SAN-USMO
SAN-STL
SAN-MCI
SAN-COU
SAN-TBN
What is the cheapest month to book a flight from San Diego to Missouri?
Currently, September is the cheapest month in which you can book a flight from San Diego to Missouri (average of $71). Flying from San Diego to Missouri in March is currently the most expensive (average of $218). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to MO?
Find hourly flight availability from San Diego to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 26, 2026.
One of the essential ways to save on airfare from San Diego to Missouri is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 37% on airfare.
How much does it cost to fly round-trip from San Diego to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 26, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from San Diego to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Missouri by cabin class
Find flights from San Diego to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Missouri flights
Browse other San Diego and Missouri flight options. Last updated on March 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to Missouri flights
Consider these flights traveling from San Diego to Missouri.
Top 7 airlines flying from San Diego to Missouri
Discover the top 7 airlines that operate flights from San Diego to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$92 | Average$216 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$104 | Average$220 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$133 | Average$315 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$209 | Average$386 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$218 | Average$421 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$219 | Average$350 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$266 | Average$463 | FlexibilityNo cancel fee | On-time63% |