Missouri

$60+ Cheap flights from San Diego (SAN) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — STL
Mar 13 — Mar 201
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Cheap flight deals from San Diego to Missouri

Cheapest flights from San Diego to Missouri
Explore the most affordable flight options available from San Diego to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:05 am
SAN
-
STL
1 stop10h 07m
Frontier
Sat 5/28:12 pm
STL
-
SAN
1 stop29h 49m
Frontier
Deal found 2/8$128
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1012:36 pm
SAN
-
MCI
1 stop22h 54m
Frontier
Sat 5/162:51 pm
MCI
-
SAN
1 stop7h 13m
Frontier
Deal found 2/11$134
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:05 am
SAN
-
STL
1 stop10h 07m
Frontier
Thu 4/308:12 pm
STL
-
SAN
1 stop14h 22m
Frontier
Deal found 2/8$142
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:05 am
SAN
-
STL
1 stop10h 07m
Frontier
Fri 5/18:12 pm
STL
-
SAN
1 stop25h 52m
Frontier
Deal found 2/8$143
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:54 pm
SAN
-
MCI
1 stop18h 15m
Multiple Airlines
Mon 4/202:15 pm
MCI
-
SAN
1 stop11h 46m
Multiple Airlines
Deal found 2/10$153
This Frontier deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:25 am
SAN
-
MCI
1 stop11h 23m
Frontier
Mon 3/28:33 pm
MCI
-
SAN
1 stop5h 35m
Frontier
Deal found 2/7$169
This Frontier deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:11 am
SAN
-
STL
1 stop6h 42m
Frontier
Sat 2/282:51 pm
STL
-
SAN
1 stop11h 17m
Frontier
Deal found 2/7$169
This Expedia deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:45 am
SAN
-
MCI
1 stop4h 59m
Frontier
Thu 3/56:54 pm
MCI
-
SAN
1 stop5h 25m
Frontier
Deal found 2/10$173
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:54 pm
SAN
-
MCI
1 stop18h 15m
Multiple Airlines
Sat 4/118:43 pm
MCI
-
SAN
1 stop25h 43m
Multiple Airlines
Deal found 2/11$176
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:25 am
SAN
-
MCI
1 stop11h 30m
Multiple Airlines
Wed 3/117:00 am
MCI
-
SAN
1 stop8h 13m
Multiple Airlines
Deal found 2/9$179
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:25 am
SAN
-
MCI
1 stop11h 33m
Frontier
Fri 4/108:43 pm
MCI
-
SAN
1 stop29h 19m
Frontier
Deal found 2/11$180
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/159:18 pm
SAN
-
STL
1 stop10h 31m
Frontier
Fri 3/208:12 pm
STL
-
SAN
1 stop29h 56m
Frontier
Deal found 2/10$189

Find flight deals from San Diego to Missouri

Keep the following information in mind while searching for San Diego to Missouri flight deals. Data was last updated February 11, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$128
(Kiwi.com)

One-way from

$60
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$363

Good round-trip deal

$393 or less

Good one-way deal

$224 or less
Provider with most accurate pricing for San Diego-Lambert-St Louis flight deals.
Provider most trusted by Cheapflights users for San Diego-Lambert-St Louis flights.
From San Diego to Missouri
One-way flight from San Diego to Missouri
Highest demand for flights based on searches. 7% potential increase in price ($33 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Average for round-trip flights in February 2026
Price to beat on a round-trip flight from San Diego to Missouri.
Price to beat on a one-way flight from San Diego to Missouri.

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from San Diego to Missouri that are best for you.

Fly from

San Diego

Fly to

Missouri

Route

Depart

Return

Price

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Sat 4/25

7:05 am-7:12 pm

1 stop10h 07m

Lambert-St Louis

Thu 4/30

8:12 pm-8:34 am

1 stop14h 22m

$142

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Sat 4/25

7:05 am-7:12 pm

1 stop10h 07m

Lambert-St Louis

Fri 5/1

8:12 pm-2:25 pm

2 stops20h 13m

$169

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

Tue 4/7

6:25 am-7:58 pm

1 stop11h 33m

Kansas City

Fri 4/10

8:43 pm-12:02 am

1 stop29h 19m

$180

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Sun 3/15

9:18 pm-9:49 am

1 stop10h 31m

Lambert-St Louis

Fri 3/20

8:12 pm-12:08 am

1 stop29h 56m

$189

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

Fri 2/27

8:35 am-7:48 pm

1 stop9h 13m

Kansas City

Sun 3/1

1:44 pm-12:08 am

1 stop12h 24m

$190

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

Mon 4/6

8:54 pm-5:09 pm

1 stop18h 15m

Kansas City

Sat 4/11

8:43 pm-7:21 am

2 stops12h 38m

$214

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

Sat 5/23

4:07 pm-11:27 pm

1 stop5h 20m

Kansas City

Fri 5/29

6:04 am-9:05 am

1 stop5h 01m

$216

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

Fri 5/22

9:30 pm-9:19 am

1 stop9h 49m

Kansas City

Fri 5/29

5:40 am-11:24 am

1 stop7h 44m

$217

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

Tue 2/24

10:35 pm-8:42 am

1 stop8h 07m

Kansas City

Fri 2/27

2:24 pm-6:52 pm

1 stop6h 28m

$217

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

Thu 5/7

7:35 pm-2:04 pm

1 stop16h 29m

Kansas City

Tue 5/12

7:00 am-3:53 pm

1 stop10h 53m

$217

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/9

Showing 1-10 of 60 results
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Best time to book a flight from San Diego to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Missouri

What is the cheapest month to book a flight from San Diego to Missouri?

Currently, September is the cheapest month in which you can book a flight from San Diego to Missouri (average of $71). Flying from San Diego to Missouri in March is currently the most expensive (average of $192). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to MO?

Find hourly flight availability from San Diego to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 11, 2026.

One of the essential ways to save on airfare from San Diego to Missouri is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 36% on airfare.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 11, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from San Diego to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.6

Food

7.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Crew

8.6

Food

7.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Crew

8.6

Food

7.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Crew

8.6

Food

7.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Crew

8.6

Food

7.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Crew

8.6

Food

7.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Diego to Missouri?

    Most people fly from San Diego (SAN) if they book a flight from San Diego to Missouri. San Diego is conveniently located just 2.6 mi from San Diego’s city center.

  • How popular is this San Diego to Missouri flight route?

  • How long is the flight from San Diego to Missouri?

    A quick flight from San Diego to Missouri can take about 5h 20m. Frontier provides one of the quickest options available for as low as $216. Airlines will cover a distance of 1330 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from San Diego to Missouri one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $73. However, be on the lookout for offers from Frontier and United Airlines, as they are both options that can get you from San Diego to Missouri for a low price.

  • What are the most popular routes from San Diego to Missouri?

  • What are the cheapest flights from San Diego to Missouri?

    The cheapest flight price from San Diego to Missouri is $168. On average you can expect to pay $371. The most popular route, (San Diego - Kansas City), can usually be booked for $179.

  • Can I find deals for flights from San Diego to Missouri that include hotel bookings?

    Yes. In addition to deals on San Diego to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Missouri.

  • Can I find deals for business class flights from San Diego to Missouri?

    Yes. Cheapflights offers flight deals from San Diego to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Missouri?

    Currently, September is the cheapest month in which you can book a flight from San Diego to Missouri (average of $71). Flying from San Diego to Missouri in March is currently the most expensive (average of $192). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for San Diego to Missouri

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from San Diego to Missouri

Discover the top 6 airlines that operate flights from San Diego to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$92Average$216FlexibilityNo cancel feeOn-time65%
FrontierCheapest$104Average$221FlexibilityNo cancel feeOn-time62%
DeltaCheapest$133Average$275FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$218Average$406FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$237Average$357FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$268Average$473FlexibilityNo cancel feeOn-time63%

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