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$58+ Cheap flights from San Diego (SAN) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/20. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — STL
dic. 13 — dic. 201
sáb. 12/13
sáb. 12/20
1 adult, Economy
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Find flight deals from San Diego to Missouri

Cheapest flights from San Diego to Missouri
Explore the most affordable flight options available from San Diego to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/166:34 amSAN - STL
1 stop25h 40mFrontier
mié. 1/77:43 pmSTL - SAN
1 stop25h 32mFrontier
Deal found 11/10$129
This CheapOair deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/116:34 amSAN - STL
1 stop25h 40mFrontier
lun. 12/157:43 pmSTL - SAN
1 stop6h 16mFrontier
Deal found 11/12$130
This Frontier deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/126:34 amSAN - MCI
1 stop5h 19mFrontier
lun. 12/158:45 pmMCI - SAN
1 stop5h 14mFrontier
Deal found 11/12$134
This CheapOair deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/43:47 pmSAN - STL
1 stop18h 25mFrontier
dom. 12/71:16 pmSTL - SAN
1 stop25h 22mFrontier
Deal found 11/11$134
This Expedia deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/156:34 amSAN - MCI
1 stop11h 16mFrontier
sáb. 1/38:45 pmMCI - SAN
1 stop5h 14mFrontier
Deal found 11/13$137
This CheapOair deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/26:25 amSAN - STL
1 stop25h 49mFrontier
mié. 12/107:43 pmSTL - SAN
1 stop25h 32mFrontier
Deal found 11/12$137
This Frontier deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/296:25 amSAN - MCI
1 stop11h 25mFrontier
sáb. 1/38:45 pmMCI - SAN
1 stop5h 14mFrontier
Deal found 11/11$144
This CheapOair deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/184:47 pmSAN - STL
1 stop15h 15mFrontier
dom. 1/410:10 pmSTL - SAN
1 stop16h 28mFrontier
Deal found 11/10$144
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/166:34 amSAN - STL
1 stop25h 40mFrontier
vie. 1/28:42 pmSTL - SAN
1 stop14h 05mFrontier
Deal found 11/10$145
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/166:34 amSAN - STL
1 stop25h 40mFrontier
lun. 1/510:10 pmSTL - SAN
1 stop16h 28mFrontier
Deal found 11/10$146
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/217:31 pmSAN - STL
1 stop12h 31mFrontier
dom. 11/237:57 pmSTL - SAN
1 stop14h 04mFrontier
Deal found 11/12$153
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/184:47 pmSAN - STL
1 stop15h 15mFrontier
mié. 1/77:43 pmSTL - SAN
1 stop25h 32mFrontier
Deal found 11/10$155

Cheap flight deals from San Diego to Missouri

Keep the following information in mind while searching for San Diego to Missouri flight deals. Data was last updated noviembre 13, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$129
(Kiwi.com)

One-way from

$58
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$404

Good round-trip deal

$318 or less

Good one-way deal

$166 or less
Provider with most accurate pricing for San Diego-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Diego-Lambert-St Louis flights.
Search Deals
From San Diego to Missouri
Search Deals
One-way flight from San Diego to Missouri
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($34 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from San Diego to Missouri.
Search Deals
Price to beat on a one-way flight from San Diego to Missouri.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 13, 2025.
Use the filters below to find and compare flights from San Diego to Missouri that are best for you.

Fly from

San Diego

Fly to

Missouri

Route

Depart

Return

Price

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

jue. 12/4

8:10 pm-10:14 am

1 stop12h 04m

Lambert-St Louis

sáb. 12/6

7:43 pm-11:59 pm

1 stop6h 16m

$130

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

vie. 12/12

6:34 am-1:53 pm

1 stop5h 19m

Kansas City

lun. 12/15

8:45 pm-11:59 pm

1 stop5h 14m

$134

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

jue. 1/15

11:50 am-6:32 pm

1 stop28h 42m

Lambert-St Louis

mar. 1/20

4:45 pm-11:31 pm

2 stops32h 46m

$162

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

jue. 12/11

8:10 pm-1:53 pm

1 stop15h 43m

Kansas City

jue. 12/18

7:00 am-12:11 pm

1 stop7h 11m

$166

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

vie. 12/5

4:47 pm-10:14 am

1 stop15h 27m

Lambert-St Louis

lun. 12/8

12:07 pm-11:59 pm

2 stops13h 52m

$176

San DiegoKansas City

SAN - MCI

SANMCI

San Diego

sáb. 12/20

4:47 pm-7:51 pm

1 stop25h 04m

Kansas City

lun. 12/29

8:45 pm-11:59 pm

1 stop29h 14m

$219

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

lun. 12/22

7:21 pm-9:25 pm

1 stop24h 04m

Lambert-St Louis

sáb. 1/3

7:43 pm-10:13 am

2 stops16h 30m

$227

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

mar. 2/24

6:15 am-2:58 pm

1 stop6h 43m

Lambert-St Louis

mié. 2/25

10:18 am-6:18 pm

1 stop10h 00m

$241

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

mié. 12/17

8:00 am-6:33 pm

1 stop8h 33m

Lambert-St Louis

mié. 1/7

6:10 am-10:48 am

1 stop6h 38m

$241

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

mié. 12/17

7:50 am-4:49 pm

1 stop6h 59m

Lambert-St Louis

mar. 1/6

5:00 pm-10:47 pm

1 stop7h 47m

$241

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Showing 1-10 of 60 results
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Best time to book a flight from San Diego to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Missouri

What is the cheapest month to book a flight from San Diego to Missouri?

Currently, September is the cheapest month in which you can book a flight from San Diego to Missouri (average of $71). Flying from San Diego to Missouri in March is currently the most expensive (average of $192). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to MO?

Find hourly flight availability from San Diego to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 13, 2025.

One of the essential ways to save on airfare from San Diego to Missouri is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 15% on airfare.

What is the cheapest day to fly from San Diego to Missouri?

Use this chart to determine the cheapest time to fly round-trip from San Diego to Missouri. Price data was last updated on December 8, 2024.

Travelers seeking maximum savings on their San Diego to Missouri flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated noviembre 13, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from San Diego to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
7.9
Good
8,007 reviews
Southwest
8.0
Very good
4,242 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
9,017 reviews
Southwest
8.0
Very good
4,242 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,051 reviews
Southwest
8.0
Very good
4,242 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Frontier
5.8
Fair
3,109 reviews
Southwest
8.0
Very good
4,242 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Diego to Missouri?

    Most people fly from San Diego (SAN) if they book a flight from San Diego to Missouri. San Diego is conveniently located just 2.6 mi from San Diego’s city center.

  • How popular is this San Diego to Missouri flight route?

    Within the past month, 1 users have taken a look at flights from San Diego to Missouri.

  • How long is the flight from San Diego to Missouri?

    A quick flight from San Diego to Missouri can take about 5h 42m. Frontier provides one of the quickest options available for as low as $269. Airlines will cover a distance of 1378 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from San Diego to Missouri one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $121. However, be on the lookout for offers from Southwest and United Airlines, as they are both options that can get you from San Diego to Missouri for a low price.

  • What are the most popular routes from San Diego to Missouri?

    The most popular flight routes from San Diego to Missouri are San Diego - Lambert-St Louis, San Diego - Kansas City and San Diego - Springfield-Branson.

  • What are the cheapest flights from San Diego to Missouri?

    The cheapest flight price from San Diego to Missouri is $113. On average you can expect to pay $314. The most popular route, (San Diego - Lambert-St Louis), can usually be booked for $199.

  • Can I find deals for flights from San Diego to Missouri that include hotel bookings?

    Yes. In addition to deals on San Diego to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Missouri.

  • Can I find deals for business class flights from San Diego to Missouri?

    Yes. Cheapflights offers flight deals from San Diego to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Missouri?

    Currently, September is the cheapest month in which you can book a flight from San Diego to Missouri (average of $71). Flying from San Diego to Missouri in March is currently the most expensive (average of $192). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Diego to Missouri

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Top 6 airlines flying from San Diego to Missouri

Discover the top 6 airlines that operate flights from San Diego to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$105Average$230FlexibilityNo cancel feeOn-time65%
FrontierCheapest$117Average$261FlexibilityNo cancel feeOn-time62%
DeltaCheapest$138Average$282FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$225Average$405FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$236Average$382FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$272Average$480FlexibilityNo cancel feeOn-time63%

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