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$257+ Cheap flights from Panama City (PTY) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — STL
ago. 4 — ago. 111
lun. 8/4
lun. 8/11
1 adult, Economy
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Cheap flight deals from Panama City to Missouri

Keep the following information in mind while searching for Panama City to Missouri flight deals. Data was last updated julio 30, 2025.

Round-trip from

$418
(United Airlines)

One-way from

$313
(Mytrip)

Popular in

September

Cheapest in

April

Average price

$613
From Panama City Tocumen Intl to Missouri
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One-way flight from Panama City Tocumen Intl to Missouri
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Highest demand for flights based on searches. 1% potential increase in price ($11 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Panama City to Missouri

Cheapest flights from Panama City to Missouri
Explore the most affordable flight options available from Panama City to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 30, 2025.

This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/12:10 pmPTY - MCI
1 stop9h 34mDelta
lun. 10/65:56 amMCI - PTY
1 stop7h 00mDelta
Deal found 7/28$418
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/2510:00 amPTY - MCI
1 stop12h 27mUnited Airlines
lun. 9/296:05 amMCI - PTY
1 stop12h 32mUnited Airlines
Deal found 7/27$427
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/33:31 pmPTY - MCI
1 stop8h 28mAmerican Airlines
mar. 10/75:00 amMCI - PTY
1 stop9h 00mAmerican Airlines
Deal found 7/30$435
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/272:10 pmPTY - STL
1 stop7h 50mDelta
mar. 9/306:01 amSTL - PTY
1 stop6h 54mDelta
Deal found 7/27$546
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/2710:00 amPTY - STL
1 stop11h 58mUnited Airlines
mar. 9/306:30 amSTL - PTY
2 stops12h 07mUnited Airlines
Deal found 7/27$550
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/273:30 pmPTY - STL
1 stop8h 29mAmerican Airlines
vie. 9/55:28 amSTL - PTY
1 stop9h 03mAmerican Airlines
Deal found 7/29$565
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/253:30 pmPTY - SGF
1 stop26h 54mUnited Airlines
lun. 9/293:05 pmSGF - PTY
1 stop27h 32mUnited Airlines
Deal found 7/28$565
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/15:25 pmPTY - MCI
3 stops29h 42mMultiple Airlines
lun. 10/65:15 amMCI - PTY
3 stops27h 40mMultiple Airlines
Deal found 7/30$589
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/253:31 pmPTY - SGF
2 stops25h 29mAmerican Airlines
lun. 9/292:23 pmSGF - PTY
2 stops22h 32mAmerican Airlines
Deal found 7/29$670
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/73:20 amPTY - STL
2 stops30h 20mMultiple Airlines
sáb. 8/233:02 pmSTL - PTY
1 stop28h 31mMultiple Airlines
Deal found 7/27$689

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 30, 2025.
Use the filters below to find and compare flights from Panama City to Missouri that are best for you.

Fly from

Panama City

Fly to

Missouri

Route

Depart

Return

Price

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

mié. 10/1

2:10 pm-11:44 pm

1 stop9h 34m

Kansas City

lun. 10/6

5:56 am-12:56 pm

1 stop7h 00m

$418

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

jue. 9/25

10:00 am-10:27 pm

1 stop12h 27m

Kansas City

lun. 9/29

8:10 am-6:37 pm

1 stop10h 27m

$427

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

vie. 10/3

3:31 pm-11:59 pm

1 stop8h 28m

Kansas City

mar. 10/7

5:00 am-2:00 pm

1 stop9h 00m

$435

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

sáb. 9/27

2:10 pm-10:00 pm

1 stop7h 50m

Lambert-St Louis

mar. 9/30

6:01 am-12:55 pm

1 stop6h 54m

$546

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

sáb. 9/27

10:00 am-9:58 pm

1 stop11h 58m

Lambert-St Louis

mar. 9/30

6:30 am-6:37 pm

2 stops12h 07m

$550

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

mié. 8/27

3:30 pm-11:59 pm

1 stop8h 29m

Lambert-St Louis

vie. 9/5

5:28 am-2:31 pm

1 stop9h 03m

$565

Panama CitySpringfield

PTY - SGF

PTYSGF

Panama City Tocumen Intl

jue. 9/25

3:30 pm-6:24 pm

1 stop26h 54m

Springfield-Branson

lun. 9/29

3:05 pm-6:37 pm

1 stop27h 32m

$565

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

mié. 10/1

5:25 pm-11:07 pm

3 stops29h 42m

Kansas City

lun. 10/6

5:15 am-8:55 am

3 stops27h 40m

$589

Panama CitySpringfield

PTY - SGF

PTYSGF

Panama City Tocumen Intl

jue. 9/25

3:31 pm-5:00 pm

2 stops25h 29m

Springfield-Branson

lun. 9/29

2:23 pm-12:55 pm

2 stops22h 32m

$670

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

sáb. 9/13

3:40 pm-9:40 am

2 stops18h 00m

Lambert-St Louis

sáb. 9/20

1:00 pm-12:10 am

3 stops35h 10m

$912

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Showing 1-10 of 18 results
1
2

Best time to book a flight from Panama City to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Missouri

What is the cheapest month to book a flight from Panama City to Missouri?

Currently, August is the cheapest month in which you can book a flight from Panama City to Missouri (average of $311). Flying from Panama City to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to MO?

Find hourly flight availability from Panama City to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Missouri as you normally would.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated julio 30, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Panama City to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
Avianca
6.7
Okay
2,387 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Missouri?

    For a flight from Panama City to Missouri, you will be flying from Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city.

  • What are the cheapest airlines to fly from Panama City to Missouri one-way?

    $329 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $333 and $345, respectively.

  • What are the most popular routes from Panama City to Missouri?

    The most popular flight routes from Panama City to Missouri are Panama City Tocumen Intl - Lambert-St Louis, Panama City Tocumen Intl - Kansas City and Panama City Tocumen Intl - Springfield-Branson.

  • Can I find deals for flights from Panama City to Missouri that include hotel bookings?

    Yes. In addition to deals on Panama City to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Missouri.

  • Can I find deals for business class flights from Panama City to Missouri?

    Yes. Cheapflights offers flight deals from Panama City to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Panama City to Missouri (average of $311). Flying from Panama City to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Panama City to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama City to Missouri

Discover the top 2 airlines that operate flights from Panama City to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$252Average$630FlexibilityNo cancel feeOn-time69%
DeltaCheapest$354Average$558FlexibilityNo cancel feeOn-timeN/A

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