$277+ Cheap flights from Panama City (PTY) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from Panama City to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Missouri
Keep the following information in mind while searching for Panama City to Missouri flight deals. Data was last updated junio 12, 2025.
Round-trip from | $418 (United Airlines) |
|---|---|
One-way from | $281 (Kiwi.com) |
Popular in | September |
Cheapest in | April |
Average price | $649 |
Find flight deals from Panama City to Missouri
Cheapest flights from Panama City to MissouriExplore the most affordable flight options available from Panama City to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.
Explore the most affordable flight options available from Panama City to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Avianca deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Panama City to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Panama CityKansas City
PTY - MCI
PTYMCI
Panama City Tocumen Intl
mié. 10/1
10:00 am-10:27 pm
1 stop12h 27m
Kansas City
lun. 10/6
6:27 pm-2:14 pm
2 stops19h 47m
Panama CityKansas City
PTY - MCI
PTYMCI
Panama City Tocumen Intl
vie. 8/15
2:05 pm-4:47 pm
1 stop26h 42m
Kansas City
mar. 8/19
4:11 pm-12:50 pm
1 stop20h 39m
Panama CityKansas City
PTY - MCI
PTYMCI
Panama City Tocumen Intl
vie. 9/26
3:34 pm-11:59 pm
1 stop8h 25m
Kansas City
dom. 10/5
5:06 am-2:31 pm
1 stop9h 25m
Panama CitySt. Louis
PTY - STL
PTYSTL
Panama City Tocumen Intl
mié. 8/27
2:05 pm-4:06 pm
1 stop26h 01m
Lambert-St Louis
mié. 9/10
5:11 pm-12:49 pm
1 stop19h 38m
Panama CitySt. Louis
PTY - STL
PTYSTL
Panama City Tocumen Intl
mié. 8/27
3:30 pm-11:59 pm
1 stop8h 29m
Lambert-St Louis
vie. 9/5
5:28 am-2:31 pm
1 stop9h 03m
Panama CitySt. Louis
PTY - STL
PTYSTL
Panama City Tocumen Intl
vie. 8/22
3:30 pm-10:40 am
2 stops19h 10m
Lambert-St Louis
jue. 9/11
6:15 am-2:14 pm
1 stop7h 59m
Panama CitySpringfield
PTY - SGF
PTYSGF
Panama City Tocumen Intl
dom. 8/3
8:10 am-6:11 pm
1 stop10h 01m
Springfield-Branson
mié. 8/13
6:00 am-12:50 pm
1 stop6h 50m
Panama CityKansas City
PTY - MCI
PTYMCI
Panama City Tocumen Intl
mié. 7/16
3:20 am-5:09 pm
3 stops37h 49m
Kansas City
dom. 8/17
6:43 pm-12:45 am
3 stops30h 02m
Panama CitySt. Louis
PTY - STL
PTYSTL
Panama City Tocumen Intl
dom. 8/17
8:10 pm-8:00 pm
3 stops23h 50m
Lambert-St Louis
dom. 12/21
1:00 pm-12:20 am
3 stops34h 20m
Panama CitySt. Louis
PTY - STL
PTYSTL
Panama City Tocumen Intl
mar. 8/26
3:20 am-7:27 pm
2 stops16h 07m
Lambert-St Louis
vie. 9/5
8:15 am-12:45 am
2 stops16h 30m
Best time to book a flight from Panama City to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Panama City with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Missouri
What is the cheapest month to book a flight from Panama City to Missouri?
Currently, August is the cheapest month in which you can book a flight from Panama City to Missouri (average of $311). Flying from Panama City to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PTY to MO?
Find hourly flight availability from Panama City to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Missouri as you normally would.
Rainfall in Missouri by month
Plan your trip to Missouri by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.
Temperature in Missouri by month
Plan your trip to Missouri by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated junio 12, 2025.
To help decide which airline to fly from Panama City to Missouri, see what other customers have to say about Delta, United Airlines and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
Comfort
Food
Overall
Entertainment
Crew
Reviews
Kim,May 2025
PIH - SLC
Boarding
Comfort
Food
Overall
Entertainment
Crew
Reviews
Kim,May 2025
PIH - SLC
Boarding
Comfort
Food
Overall
Entertainment
Crew
Reviews
Kim,May 2025
PIH - SLC
Boarding
Comfort
Food
Overall
Entertainment
Crew
Reviews
Kim,May 2025
PIH - SLC
Boarding
Comfort
Food
Overall
Entertainment
Crew
Reviews
Kim,May 2025
PIH - SLC
Related info for your journey
Find useful and relevant information for your journey from Panama City to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Panama City to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Panama City to Missouri
Discover the top 2 airlines that operate flights from Panama City to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$354 | Average$558 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$420 | Average$556 | FlexibilityNo cancel fee | On-time69% |