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$277+ Cheap flights from Panama City (PTY) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/24. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — STL
oct. 17 — oct. 241
vie. 10/17
vie. 10/24
1 adult, Economy
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Cheap flight deals from Panama City to Missouri

Keep the following information in mind while searching for Panama City to Missouri flight deals. Data was last updated septiembre 17, 2025.

Round-trip from

$418
(United Airlines)

One-way from

$277
(United Airlines)

Popular in

July

Cheapest in

April

Average price

$662
From Panama City Tocumen Intl to Missouri
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One-way flight from Panama City Tocumen Intl to Missouri
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Highest demand for flights based on searches. 3% potential increase in price ($18 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Panama City to Missouri

Cheapest flights from Panama City to Missouri
Explore the most affordable flight options available from Panama City to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 17, 2025.

This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/1010:00 amPTY - MCI
1 stop12h 10mUnited Airlines
mar. 11/256:15 amMCI - PTY
1 stop12h 23mUnited Airlines
Deal found 9/16$418
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/98:55 amPTY - MCI
1 stop14h 33mUnited Airlines
mié. 11/268:10 amMCI - PTY
1 stop10h 28mUnited Airlines
Deal found 9/16$437
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/113:37 pmPTY - MCI
1 stop7h 58mDelta
jue. 11/206:38 pmMCI - PTY
1 stop24h 21mDelta
Deal found 9/16$458
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/153:37 pmPTY - MCI
1 stop23h 30mDelta
jue. 11/206:38 pmMCI - PTY
1 stop24h 21mDelta
Deal found 9/16$477
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/128:55 amPTY - MCI
1 stop28h 06mUnited Airlines
dom. 11/236:35 pmMCI - PTY
2 stops19h 10mUnited Airlines
Deal found 9/16$484
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/94:41 pmPTY - MCI
2 stops17h 15mUnited Airlines
jue. 11/208:10 amMCI - PTY
1 stop10h 28mUnited Airlines
Deal found 9/16$504
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/1610:00 amPTY - MCI
1 stop12h 27mUnited Airlines
jue. 10/236:05 amMCI - PTY
1 stop12h 32mUnited Airlines
Deal found 9/16$511
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/153:37 pmPTY - MCI
1 stop23h 30mDelta
lun. 11/246:38 pmMCI - PTY
1 stop18h 34mDelta
Deal found 9/16$515
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/104:41 pmPTY - MCI
2 stops22h 40mUnited Airlines
dom. 11/238:10 amMCI - PTY
1 stop10h 28mUnited Airlines
Deal found 9/16$518
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/710:00 amPTY - MCI
1 stop12h 27mUnited Airlines
jue. 1/88:05 amMCI - PTY
1 stop8h 02mUnited Airlines
Deal found 9/15$531
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/307:55 amPTY - STL
1 stop26h 44mUnited Airlines
mar. 11/118:20 amSTL - PTY
1 stop29h 25mUnited Airlines
Deal found 9/15$537
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/143:30 pmPTY - STL
1 stop27h 27mUnited Airlines
jue. 10/238:25 amSTL - PTY
1 stop10h 12mUnited Airlines
Deal found 9/15$558

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Panama City to Missouri that are best for you.

Fly from

Panama City

Fly to

Missouri

Route

Depart

Return

Price

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

jue. 11/13

4:41 pm-8:56 am

2 stops17h 15m

Kansas City

mié. 11/26

6:15 am-7:38 pm

1 stop12h 23m

$418

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

jue. 11/13

4:41 pm-8:56 am

2 stops17h 15m

Kansas City

mar. 11/25

8:10 am-7:38 pm

1 stop10h 28m

$418

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

mié. 11/12

4:41 pm-10:40 am

2 stops18h 59m

Kansas City

mié. 11/26

6:15 am-7:38 pm

1 stop12h 23m

$418

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

sáb. 11/15

3:37 pm-2:07 pm

1 stop23h 30m

Kansas City

mar. 11/25

6:38 pm-2:12 pm

1 stop18h 34m

$437

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

vie. 11/14

4:41 pm-2:21 pm

2 stops22h 40m

Kansas City

mié. 11/26

6:15 am-7:38 pm

1 stop12h 23m

$437

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

dom. 11/9

4:41 pm-2:21 pm

2 stops22h 40m

Kansas City

mié. 11/26

8:10 am-7:38 pm

1 stop10h 28m

$437

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

vie. 11/14

8:55 am-10:28 pm

1 stop14h 33m

Kansas City

mar. 11/25

6:15 am-7:38 pm

1 stop12h 23m

$437

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

sáb. 11/15

4:41 pm-9:29 am

1 stop17h 48m

Kansas City

mié. 11/26

6:15 am-7:38 pm

1 stop12h 23m

$437

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

dom. 11/9

8:55 am-10:28 pm

1 stop14h 33m

Kansas City

mar. 11/25

8:10 am-7:38 pm

1 stop10h 28m

$437

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

mar. 2/3

8:55 am-3:52 pm

1 stop7h 57m

Lambert-St Louis

mar. 3/3

6:45 pm-5:07 pm

2 stops21h 22m

$515

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 27 results
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Best time to book a flight from Panama City to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Missouri

What is the cheapest month to book a flight from Panama City to Missouri?

Currently, August is the cheapest month in which you can book a flight from Panama City to Missouri (average of $311). Flying from Panama City to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to MO?

Find hourly flight availability from Panama City to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Missouri as you normally would.

How much does it cost to fly round-trip from Panama City to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated septiembre 17, 2025.
Read reviews from past customers who have flown Delta and United Airlines from Panama City to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Related info for your journey

Find useful and relevant information for your journey from Panama City to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Missouri?

    For a flight from Panama City to Missouri, you will be flying from Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city.

  • How long is the flight from Panama City to Missouri?

    United Airlines and Delta can get you from Panama City to Missouri in just under 17h 15m. Your travel time can differ by up to 6h 15m. Panama City and Missouri are separated by a distance of 2292 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Panama City to Missouri one-way?

    $277 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $277 and $338, respectively.

  • What are the most popular routes from Panama City to Missouri?

    The most popular flight routes from Panama City to Missouri are Panama City Tocumen Intl - Kansas City, Panama City Tocumen Intl - Lambert-St Louis and Panama City Tocumen Intl - Springfield-Branson.

  • Can I find deals for flights from Panama City to Missouri that include hotel bookings?

    Yes. In addition to deals on Panama City to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Missouri.

  • Can I find deals for business class flights from Panama City to Missouri?

    Yes. Cheapflights offers flight deals from Panama City to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Panama City to Missouri (average of $311). Flying from Panama City to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama City to Missouri

Discover the top 2 airlines that operate flights from Panama City to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$252Average$626FlexibilityNo cancel feeOn-time69%
DeltaCheapest$354Average$558FlexibilityNo cancel feeOn-timeN/A

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