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$300+ Cheap flights from Panama City (PTY) to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — BUF
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from Panama City to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$548
(United Airlines)

One-way from

$300
(Delta)

Popular in

October

Cheapest in

June

Average price

$480
From Panama City Tocumen Intl to Buffalo
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One-way flight from Panama City Tocumen Intl to Buffalo
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Highest demand for flights based on searches. 22% potential increase in price ($172 potential increase over avg. RT price).
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Cheapest flight prices on average. 17% potential price decrease ($90 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Panama City to Buffalo

Cheapest flights from Panama City to Buffalo
Explore the most affordable flight options available from Panama City to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/57:55 amPTY - BUF
2 stops13h 33mUnited Airlines
Mon 7/76:00 amBUF - PTY
1 stop8h 50mUnited Airlines
Deal found 7/1$535
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/192:05 pmPTY - BUF
1 stop8h 52mDelta
Mon 9/86:00 amBUF - PTY
1 stop7h 50mDelta
Deal found 7/3$617
This Mytrip deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/43:25 amPTY - BUF
3 stops30h 19mMultiple Airlines
Mon 7/711:53 amBUF - PTY
3 stops23h 32mMultiple Airlines
Deal found 7/1$2,043

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Panama City to Buffalo that are best for you.

Fly from

Panama City

Fly to

Buffalo

Route

Depart

Return

Price

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Tue 8/19

10:55 pm-9:16 pm

2 stops21h 21m

Buffalo

Mon 9/8

8:00 pm-6:37 pm

2 stops23h 37m

$548

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Tue 8/19

2:05 pm-11:57 pm

1 stop8h 52m

Buffalo

Mon 9/8

6:00 am-12:50 pm

1 stop7h 50m

$617

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Mon 8/18

3:25 am-7:01 pm

2 stops14h 36m

Buffalo

Mon 9/8

8:25 pm-8:55 am

2 stops13h 30m

$2,181

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Wed 10/15

2:12 pm-11:54 pm

1 stop8h 42m

$300

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Wed 10/15

8:40 am-3:44 pm

3 stops30h 04m

$392

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Fri 10/31

3:41 pm-4:38 pm

3 stops23h 57m

$3,883

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from Panama City to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated July 3, 2025.
Peruse reviews from past customers who have flown with Delta and United Airlines from Panama City to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
United Airlines
7.4
Good
8,861 reviews
Delta
8.0
Very good
7,982 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Panama City to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City to Buffalo round-trip?

    Currently priced at $548, United Airlines will fly you from Panama City to Buffalo and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $617. Users have found that United Airlines is 8% cheaper than the other options available to this destination.

  • Can I find deals for flights from Panama City to Buffalo that include hotel bookings?

    Yes. In addition to deals on Panama City to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Buffalo.

  • Can I find deals for business class flights from Panama City to Buffalo?

    Yes. Cheapflights offers flight deals from Panama City to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Buffalo (average of $256). Flying from Panama City to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Williamsville
Orchard Park
Batavia
Eden
Amherst
West Seneca

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