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$375+ Cheap flights from Panama City (PTY) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JAN
Sep 9 — Sep 161
Wed 9/9
Wed 9/16
1 adult, Economy
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Cheap flight deals from Panama City to Mississippi

Cheapest flights from Panama City to Mississippi
Explore the most affordable flight options available from Panama City to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.

This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:30 pm -
1 stop21h 55m
Mon 10/264:55 pm -
1 stop20h 50m
Deal found 8/7$673
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:30 pm -
1 stop28h 30m
Tue 10/276:50 am -
1 stop6h 55m
Deal found 8/7$673
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:02 pm -
2 stops21h 11m
Mon 10/266:02 pm -
2 stops19h 00m
Deal found 8/5$698
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:02 pm -
2 stops20h 24m
Tue 11/105:34 pm -
2 stops19h 39m
Deal found 8/7$700
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:00 am -
1 stop11h 56m
Thu 9/1011:44 am -
1 stop26h 30m
Deal found 8/5$705
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/231:16 pm -
2 stops19h 26m
Wed 9/3012:21 pm -
2 stops23h 55m
Deal found 8/9$708
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/31:39 pm -
1 stop9h 10m
Thu 9/105:10 am -
1 stop7h 06m
Deal found 8/5$714
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:30 pm -
1 stop28h 50m
Sat 9/269:20 am -
1 stop9h 17m
Deal found 8/6$726
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:30 pm -
2 stops19h 33m
Sun 8/306:31 pm -
2 stops24h 06m
Deal found 8/6$746
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/221:16 pm -
2 stops27h 09m
Sat 9/2612:14 pm -
2 stops24h 02m
Deal found 8/6$754
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:24 pm -
1 stop8h 45m
Tue 11/105:30 am -
1 stop7h 35m
Deal found 8/7$756
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/211:16 pm -
2 stops25h 36m
Sat 9/263:27 pm -
2 stops20h 49m
Deal found 8/6$787

Find flight deals from Panama City to Mississippi

Keep the following information in mind while searching for Panama City to Mississippi flight deals. Data was last updated August 10, 2026.

Round-trip from

$673
(United Airlines)

One-way from

$375
(United Airlines)
From Panama City Tocumen Intl to Mississippi
Search Deals
One-way flight from Panama City Tocumen Intl to Mississippi
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Panama City to Mississippi that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityGulfport

PTY Panama City Tocumen Intl - GPT Gulfport Biloxi Regional

PTYGPT

Panama City Tocumen Intl

Wed 10/21

3:30 pm-1:25 pm

1 stop21h 55m

Gulfport Biloxi Regional

Mon 10/26

4:55 pm-1:45 pm

1 stop20h 50m

$673

Panama CityJackson

PTY Panama City Tocumen Intl - JAN Jackson-Evers Intl

PTYJAN

Panama City Tocumen Intl

Mon 1/25

4:41 pm-9:18 pm

1 stop29h 37m

Jackson-Evers Intl

Mon 2/1

5:20 pm-5:12 pm

1 stop22h 52m

$673

Panama CityJackson

PTY Panama City Tocumen Intl - JAN Jackson-Evers Intl

PTYJAN

Panama City Tocumen Intl

Tue 10/20

3:30 pm-8:00 pm

1 stop28h 30m

Jackson-Evers Intl

Tue 10/27

6:50 am-1:45 pm

1 stop6h 55m

$673

Panama CityJackson

PTY Panama City Tocumen Intl - JAN Jackson-Evers Intl

PTYJAN

Panama City Tocumen Intl

Tue 1/19

4:41 pm-1:23 pm

1 stop21h 42m

Jackson-Evers Intl

Tue 1/26

12:00 pm-2:45 pm

1 stop25h 45m

$673

Panama CityGulfport

PTY Panama City Tocumen Intl - GPT Gulfport Biloxi Regional

PTYGPT

Panama City Tocumen Intl

Wed 10/21

2:02 pm-11:13 am

2 stops21h 11m

Gulfport Biloxi Regional

Mon 10/26

6:02 pm-1:02 pm

2 stops19h 00m

$698

Panama CityJackson

PTY Panama City Tocumen Intl - JAN Jackson-Evers Intl

PTYJAN

Panama City Tocumen Intl

Wed 2/3

8:55 am-1:23 pm

1 stop29h 28m

Jackson-Evers Intl

Sun 2/7

5:20 pm-5:12 pm

1 stop22h 52m

$699

Panama CityJackson

PTY Panama City Tocumen Intl - JAN Jackson-Evers Intl

PTYJAN

Panama City Tocumen Intl

Mon 1/25

8:55 am-11:13 am

1 stop27h 18m

Jackson-Evers Intl

Sat 1/30

5:20 pm-5:12 pm

1 stop22h 52m

$705

Panama CityMemphis

PTY Panama City Tocumen Intl - MEM Memphis

PTYMEM

Panama City Tocumen Intl

Thu 9/3

9:45 am-11:29 pm

1 stop13h 44m

Memphis

Thu 9/10

7:15 am-6:37 pm

2 stops11h 22m

$705

Panama CityJackson

PTY Panama City Tocumen Intl - JAN Jackson-Evers Intl

PTYJAN

Panama City Tocumen Intl

Wed 9/23

1:16 pm-8:42 am

2 stops19h 26m

Jackson-Evers Intl

Wed 9/30

12:21 pm-12:16 pm

2 stops23h 55m

$708

Panama CityMemphis

PTY Panama City Tocumen Intl - MEM Memphis

PTYMEM

Panama City Tocumen Intl

Thu 8/27

3:30 pm-11:03 am

2 stops19h 33m

Memphis

Sun 8/30

6:31 pm-6:37 pm

2 stops24h 06m

$746

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/5

Showing 1-10 of 23 resultsSorted by cheapest first
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Best time to book a flight from Panama City to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Mississippi

No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Mississippi?

    Most people fly from Panama City Tocumen Intl (PTY) if they book a flight from Panama City to Mississippi. Panama City Tocumen Intl is conveniently located just 11.4 mi from Panama City’s city center.

  • How long is the flight from Panama City to Mississippi?

    Departing from Panama City to Mississippi will take you 21h 11m. Panama City and Mississippi are separated by a distance of 1600 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Panama City to Mississippi?

    The most popular route from Panama City to Mississippi is Panama City Tocumen Intl - Jackson-Evers Intl. You may also consider Panama City Tocumen Intl - Memphis or Panama City Tocumen Intl - Gulfport Biloxi Regional.

  • Can I find deals for flights from Panama City to Mississippi that include hotel bookings?

    Yes. In addition to deals on Panama City to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Mississippi.

  • Can I find deals for business class flights from Panama City to Mississippi?

    Yes. Cheapflights offers flight deals from Panama City to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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